BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
51035019	CC(C)n1c(\C=C\C(O)C[C@@H](O)CC([O-])=O)c(-c2ccc(F)cc2)c2ccccc12	InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/p-1/b12-11+/t18?,19-/m1/s1	FJLGEFLZQAZZCD-GDOBVAKGSA-M	50007276	Sodium; 7-[3-(4-fluoro-phenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 21210							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007276	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007276&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928767	103920556					C03834	ZINC03830864	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32851	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O	InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1	BPRHUIZQVSMCRT-VEUZHWNKSA-N	18372	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::CHEMBL1496::Ros::Rosuvastatin::US9102656, Rosuvastatin ::ZD4522	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.6					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18372&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search		1HWL	446157	46518448	38545	CHEMBL1496	DB01098	2989	C03834	ZINC01535101	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32852	CC(C)n1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(c1C(=O)Nc1ccccc1)-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C33H35FN2O5/c1-21(2)36-28(18-17-26(37)19-27(38)20-29(39)40)30(23-13-15-24(34)16-14-23)31(22-9-5-3-6-10-22)32(36)33(41)35-25-11-7-4-8-12-25/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/p-1/t26-,27-/m1/s1	PNRWKVJLHGHICL-KAYWLYCHSA-M	18374	CHEMBL394937::Pyrrole-based compound, 30::sodium (3R,5R)-7-[3-(4-fluorophenyl)-4-phenyl-5-(phenylcarbamoyl)-1-(propan-2-yl)-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18374&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			60021371	46518449		CHEMBL394937			C03834	ZINC14967803	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32853	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12	InChI=1S/C25H40O6/c1-6-25(4,5)24(30)31-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-18(26)13-19(27)14-22(28)29/h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29)/t15-,16-,18+,19+,20-,21-,23-/m0/s1	XWLXKKNPFMNSFA-HGQWONQESA-N	18375	(3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid::Simvastatin::Simvastatin acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 18					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18375&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	SIM	4XW2,1HW9,6KJF,3HLF	64718	46518450					C03834	ZINC03833877	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32854	COCc1c(nc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)c1-c1ccc(F)cc1)C(C)C	InChI=1S/C26H34FNO5/c1-15(2)25-21(11-10-19(29)12-20(30)13-23(31)32)24(17-6-8-18(27)9-7-17)22(14-33-5)26(28-25)16(3)4/h6-11,15-16,19-20,29-30H,12-14H2,1-5H3,(H,31,32)/b11-10+/t19-,20-/m1/s1	SEERZIQQUAZTOL-ANMDKAQQSA-N	18376	(3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid::Cerivastatin::cid_446156	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.8					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18376&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search		1HWJ	446156	46518451	3558		DB00439	2950	C03834	ZINC11330186	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32855	CC(C)n1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(c1C(N)=O)-c1ccccn1)-c1ccc(F)cc1	InChI=1S/C26H30FN3O5/c1-15(2)30-21(11-10-18(31)13-19(32)14-22(33)34)23(16-6-8-17(27)9-7-16)24(25(30)26(28)35)20-5-3-4-12-29-20/h3-9,12,15,18-19,31-32H,10-11,13-14H2,1-2H3,(H2,28,35)(H,33,34)/p-1/t18-,19-/m1/s1	WLAYEDHSMAATOA-RTBURBONSA-M	18377	Pyridyl substituted pyrrole compound, 12::sodium (3R,5R)-7-[5-carbamoyl-3-(4-fluorophenyl)-1-(propan-2-yl)-4-(pyridin-2-yl)-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5.3					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18377&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			60021456	46518452					C03834	ZINC14967807	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32856	CCNC(=O)c1c(c(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n1C(C)C)-c1ccc(F)cc1)-c1ccccn1	InChI=1S/C28H34FN3O5/c1-4-30-28(37)27-26(22-7-5-6-14-31-22)25(18-8-10-19(29)11-9-18)23(32(27)17(2)3)13-12-20(33)15-21(34)16-24(35)36/h5-11,14,17,20-21,33-34H,4,12-13,15-16H2,1-3H3,(H,30,37)(H,35,36)/p-1/t20-,21-/m1/s1	RZGLXXTZOCSIRX-NHCUHLMSSA-M	18378	Pyridyl substituted pyrrole compound, 13::sodium (3R,5R)-7-[5-(ethylcarbamoyl)-3-(4-fluorophenyl)-1-(propan-2-yl)-4-(pyridin-2-yl)-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 21					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18378&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			60021425	46518453					C03834	ZINC14967811	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32857	CC(C)n1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(c1C#N)-c1ccccn1)-c1ccc(F)cc1	InChI=1S/C26H28FN3O4/c1-16(2)30-22(11-10-19(31)13-20(32)14-24(33)34)25(17-6-8-18(27)9-7-17)26(23(30)15-28)21-5-3-4-12-29-21/h3-9,12,16,19-20,31-32H,10-11,13-14H2,1-2H3,(H,33,34)/p-1/t19-,20-/m1/s1	SROAHSZUIFXTRD-WOJBJXKFSA-M	18379	Pyridyl substituted pyrrole compound, 11::sodium (3R,5R)-7-[5-cyano-3-(4-fluorophenyl)-1-(propan-2-yl)-4-(pyridin-2-yl)-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.8					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18379&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91895921	46518454					C03834	ZINC14967815	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32858	CC(C)n1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(c1C(=O)NCc1ccccc1)-c1ccccn1)-c1ccc(F)cc1	InChI=1S/C33H36FN3O5/c1-21(2)37-28(16-15-25(38)18-26(39)19-29(40)41)30(23-11-13-24(34)14-12-23)31(27-10-6-7-17-35-27)32(37)33(42)36-20-22-8-4-3-5-9-22/h3-14,17,21,25-26,38-39H,15-16,18-20H2,1-2H3,(H,36,42)(H,40,41)/p-1/t25-,26-/m1/s1	NSBZOVKKHKKXHM-CLJLJLNGSA-M	18380	Pyridyl substituted pyrrole compound, 15::sodium (3R,5R)-7-[5-(benzylcarbamoyl)-3-(4-fluorophenyl)-1-(propan-2-yl)-4-(pyridin-2-yl)-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.7					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18380&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			60021533	46518455					C03834	ZINC14967820	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32859	CC(C)n1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(c1C(=O)Nc1ccccc1)-c1ccccn1)-c1ccc(F)cc1	InChI=1S/C32H34FN3O5/c1-20(2)36-27(16-15-24(37)18-25(38)19-28(39)40)29(21-11-13-22(33)14-12-21)30(26-10-6-7-17-34-26)31(36)32(41)35-23-8-4-3-5-9-23/h3-14,17,20,24-25,37-38H,15-16,18-19H2,1-2H3,(H,35,41)(H,39,40)/p-1/t24-,25-/m1/s1	MTWLPOUAURCCNI-JWQCQUIFSA-M	18381	Pyridyl substituted pyrrole compound, 14::sodium (3R,5R)-7-[3-(4-fluorophenyl)-5-(phenylcarbamoyl)-1-(propan-2-yl)-4-(pyridin-2-yl)-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.4					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18381&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			60021401	46518456					C03834	ZINC14967824	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32860	CCn1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)c1C(=O)NCc1ccc(cc1)C([O-])=O)-c1ccc(F)cc1	InChI=1S/C29H33FN2O7/c1-3-32-24(13-12-22(33)14-23(34)15-25(35)36)26(19-8-10-21(30)11-9-19)17(2)27(32)28(37)31-16-18-4-6-20(7-5-18)29(38)39/h4-11,22-23,33-34H,3,12-16H2,1-2H3,(H,31,37)(H,35,36)(H,38,39)/p-2/t22-,23-/m1/s1	MFLMXRSHJVIMRF-DHIUTWEWSA-L	18382	Alkyl substituted pyrrole compound, 29f::disodium 4-[({5-[(3R,5R)-6-carboxylato-3,5-dihydroxyhexyl]-1-ethyl-4-(4-fluorophenyl)-3-methyl-1H-pyrrol-2-yl}formamido)methyl]benzoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 0.85					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18382&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947057	46518457					C03834	ZINC14967828	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32861	CCn1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)c1C(=O)NCc1cnc(C)cn1)-c1ccc(F)cc1	InChI=1S/C27H33FN4O5/c1-4-32-23(10-9-21(33)11-22(34)12-24(35)36)25(18-5-7-19(28)8-6-18)17(3)26(32)27(37)31-15-20-14-29-16(2)13-30-20/h5-8,13-14,21-22,33-34H,4,9-12,15H2,1-3H3,(H,31,37)(H,35,36)/p-1/t21-,22-/m1/s1	XOXXJOLIUVJJAA-FGZHOGPDSA-M	18383	Alkyl substituted pyrrole compound, 29e::sodium (3R,5R)-7-[1-ethyl-3-(4-fluorophenyl)-4-methyl-5-{[(5-methylpyrazin-2-yl)methyl]carbamoyl}-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.7					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18383&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			60021317	46518458					C03834	ZINC14967832	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32862	CCn1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)c1C(=O)NCc1ccc(OC)cc1)-c1ccc(F)cc1	InChI=1S/C29H35FN2O6/c1-4-32-25(14-11-22(33)15-23(34)16-26(35)36)27(20-7-9-21(30)10-8-20)18(2)28(32)29(37)31-17-19-5-12-24(38-3)13-6-19/h5-10,12-13,22-23,33-34H,4,11,14-17H2,1-3H3,(H,31,37)(H,35,36)/p-1/t22-,23-/m1/s1	SNPGLSNUWCOZAS-DHIUTWEWSA-M	18384	Alkyl substituted pyrrole compound, 29c::sodium (3R,5R)-7-[1-ethyl-3-(4-fluorophenyl)-5-{[(4-methoxyphenyl)methyl]carbamoyl}-4-methyl-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.6					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18384&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			60021532	46518459					C03834	ZINC14967836	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32864	CCn1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)c1C(=O)Nc1ccccc1)-c1ccc(F)cc1	InChI=1S/C27H31FN2O5/c1-3-30-23(14-13-21(31)15-22(32)16-24(33)34)25(18-9-11-19(28)12-10-18)17(2)26(30)27(35)29-20-7-5-4-6-8-20/h4-12,21-22,31-32H,3,13-16H2,1-2H3,(H,29,35)(H,33,34)/p-1/t21-,22-/m1/s1	WZLAXTSLBYIWOK-FGZHOGPDSA-M	18386	Alkyl substituted pyrrole compound, 29b::sodium (3R,5R)-7-[1-ethyl-3-(4-fluorophenyl)-4-methyl-5-(phenylcarbamoyl)-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.8					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18386&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			60021662	46518461					C03834	ZINC14967843	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32865	CCn1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)c1C(=O)NCc1ccc(cc1)C(=O)OC)-c1ccc(F)cc1	InChI=1S/C30H35FN2O7/c1-4-33-25(14-13-23(34)15-24(35)16-26(36)37)27(20-9-11-22(31)12-10-20)18(2)28(33)29(38)32-17-19-5-7-21(8-6-19)30(39)40-3/h5-12,23-24,34-35H,4,13-17H2,1-3H3,(H,32,38)(H,36,37)/p-1/t23-,24-/m1/s1	PQMAYIKJNUIXMQ-DNQXCXABSA-M	18387	Alkyl substituted pyrrole compound, 29d::sodium (3R,5R)-7-[1-ethyl-3-(4-fluorophenyl)-5-({[4-(methoxycarbonyl)phenyl]methyl}carbamoyl)-4-methyl-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.6					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18387&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91895923	46518462					C03834	ZINC14967847	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32866	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1ccccc1)-c1ccc(F)cc1	InChI=1S/C26H30FN3O6/c1-16(2)23-24(25(35)28-14-17-6-4-3-5-7-17)29-30(19-10-8-18(27)9-11-19)26(23)36-15-21(32)12-20(31)13-22(33)34/h3-11,16,20-21,31-32H,12-15H2,1-2H3,(H,28,35)(H,33,34)/t20-,21+/m1/s1	GJYSGJITZCUKRD-RTWAWAEBSA-N	18388	(3R,5S)-6-{[3-(benzylcarbamoyl)-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4a	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.8					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18388&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996370	46518463					C03834	ZINC14967851	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32867	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1ccccc1)-c1ccc(F)cc1	InChI=1S/C27H32FN3O6/c1-17(2)24-25(26(36)30(3)15-18-7-5-4-6-8-18)29-31(20-11-9-19(28)10-12-20)27(24)37-16-22(33)13-21(32)14-23(34)35/h4-12,17,21-22,32-33H,13-16H2,1-3H3,(H,34,35)/t21-,22+/m1/s1	ZWAXQNCNRHKSOI-YADHBBJMSA-N	18389	(3R,5S)-6-({3-[benzyl(methyl)carbamoyl]-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl}oxy)-3,5-dihydroxyhexanoic acid::oxypyrazole, 4b	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5.2					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18389&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997301	46518464					C03834	ZINC14967855	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32868	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1cccc(F)c1F)-c1ccc(F)cc1	InChI=1S/C26H28F3N3O6/c1-14(2)22-24(25(37)30-12-15-4-3-5-20(28)23(15)29)31-32(17-8-6-16(27)7-9-17)26(22)38-13-19(34)10-18(33)11-21(35)36/h3-9,14,18-19,33-34H,10-13H2,1-2H3,(H,30,37)(H,35,36)/t18-,19+/m1/s1	FDLHNOWKQMFSQT-MOPGFXCFSA-N	18390	(3R,5S)-6-[(3-{[(2,3-difluorophenyl)methyl]carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)oxy]-3,5-dihydroxyhexanoic acid::oxypyrazole, 4c	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.0					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18390&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996995	46518465					C03834	ZINC14967859	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32869	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1cccc(F)c1F)-c1ccc(F)cc1	InChI=1S/C27H30F3N3O6/c1-15(2)23-25(26(38)32(3)13-16-5-4-6-21(29)24(16)30)31-33(18-9-7-17(28)8-10-18)27(23)39-14-20(35)11-19(34)12-22(36)37/h4-10,15,19-20,34-35H,11-14H2,1-3H3,(H,36,37)/t19-,20+/m1/s1	FAVJTEGZSHCVRL-UXHICEINSA-N	18391	(3R,5S)-6-[(3-{[(2,3-difluorophenyl)methyl](methyl)carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)oxy]-3,5-dihydroxyhexanoic acid::oxypyrazole, 4d	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 14					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18391&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997588	46518466					C03834	ZINC14967863	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32870	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1ccc(C)cc1)-c1ccc(F)cc1	InChI=1S/C28H34FN3O6/c1-17(2)25-26(27(37)31(4)15-19-7-5-18(3)6-8-19)30-32(21-11-9-20(29)10-12-21)28(25)38-16-23(34)13-22(33)14-24(35)36/h5-12,17,22-23,33-34H,13-16H2,1-4H3,(H,35,36)/t22-,23+/m1/s1	JNCIACHLMHSYJU-PKTZIBPZSA-N	18392	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{methyl[(4-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4e	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 37					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18392&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997442	46518467					C03834	ZINC14967867	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32871	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1ccc(C)cc1)-c1ccc(F)cc1	InChI=1S/C27H32FN3O6/c1-16(2)24-25(26(36)29-14-18-6-4-17(3)5-7-18)30-31(20-10-8-19(28)9-11-20)27(24)37-15-22(33)12-21(32)13-23(34)35/h4-11,16,21-22,32-33H,12-15H2,1-3H3,(H,29,36)(H,34,35)/t21-,22+/m1/s1	NUJQNVHXBHEJJD-YADHBBJMSA-N	18393	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(4-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4f	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18393&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996371	46518468					C03834	ZINC14967871	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32872	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1cccc(C)c1)-c1ccc(F)cc1	InChI=1S/C27H32FN3O6/c1-16(2)24-25(26(36)29-14-18-6-4-5-17(3)11-18)30-31(20-9-7-19(28)8-10-20)27(24)37-15-22(33)12-21(32)13-23(34)35/h4-11,16,21-22,32-33H,12-15H2,1-3H3,(H,29,36)(H,34,35)/t21-,22+/m1/s1	KJCQIVZEEFILIS-YADHBBJMSA-N	18394	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(3-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4g	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.9					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18394&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996993	46518469					C03834	ZINC14967874	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32873	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1ccccc1C)-c1ccc(F)cc1	InChI=1S/C27H32FN3O6/c1-16(2)24-25(26(36)29-14-18-7-5-4-6-17(18)3)30-31(20-10-8-19(28)9-11-20)27(24)37-15-22(33)12-21(32)13-23(34)35/h4-11,16,21-22,32-33H,12-15H2,1-3H3,(H,29,36)(H,34,35)/t21-,22+/m1/s1	ZAHAKGSYZSHOLX-YADHBBJMSA-N	18395	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(2-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4h	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 17					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18395&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23648003	46518470					C03834	ZINC14967878	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32874	COc1ccc(CNC(=O)c2nn(c(OC[C@@H](O)C[C@@H](O)CC(O)=O)c2C(C)C)-c2ccc(F)cc2)cc1	InChI=1S/C27H32FN3O7/c1-16(2)24-25(26(36)29-14-17-4-10-22(37-3)11-5-17)30-31(19-8-6-18(28)7-9-19)27(24)38-15-21(33)12-20(32)13-23(34)35/h4-11,16,20-21,32-33H,12-15H2,1-3H3,(H,29,36)(H,34,35)/t20-,21+/m1/s1	IZGVKPJGRQWQJR-RTWAWAEBSA-N	18396	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(4-methoxyphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4i	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18396&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996842	46518471					C03834	ZINC14967882	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32875	COc1cccc(CNC(=O)c2nn(c(OC[C@@H](O)C[C@@H](O)CC(O)=O)c2C(C)C)-c2ccc(F)cc2)c1	InChI=1S/C27H32FN3O7/c1-16(2)24-25(26(36)29-14-17-5-4-6-22(11-17)37-3)30-31(19-9-7-18(28)8-10-19)27(24)38-15-21(33)12-20(32)13-23(34)35/h4-11,16,20-21,32-33H,12-15H2,1-3H3,(H,29,36)(H,34,35)/t20-,21+/m1/s1	SBGJIKSFKHFLEJ-RTWAWAEBSA-N	18397	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(3-methoxyphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4j	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 16					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18397&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996369	46518472					C03834	ZINC14967886	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32876	COc1ccccc1CNC(=O)c1nn(c(OC[C@@H](O)C[C@@H](O)CC(O)=O)c1C(C)C)-c1ccc(F)cc1	InChI=1S/C27H32FN3O7/c1-16(2)24-25(26(36)29-14-17-6-4-5-7-22(17)37-3)30-31(19-10-8-18(28)9-11-19)27(24)38-15-21(33)12-20(32)13-23(34)35/h4-11,16,20-21,32-33H,12-15H2,1-3H3,(H,29,36)(H,34,35)/t20-,21+/m1/s1	OVDLOXJEUYZUIU-RTWAWAEBSA-N	18398	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(2-methoxyphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4k	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 22					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18398&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996839	46518473					C03834	ZINC14967890	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32877	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1ccc(Cl)cc1)-c1ccc(F)cc1	InChI=1S/C26H29ClFN3O6/c1-15(2)23-24(25(36)29-13-16-3-5-17(27)6-4-16)30-31(19-9-7-18(28)8-10-19)26(23)37-14-21(33)11-20(32)12-22(34)35/h3-10,15,20-21,32-33H,11-14H2,1-2H3,(H,29,36)(H,34,35)/t20-,21+/m1/s1	ASGGBKLLSUVRRU-RTWAWAEBSA-N	18399	(3R,5S)-6-[(3-{[(4-chlorophenyl)methyl]carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)oxy]-3,5-dihydroxyhexanoic acid::oxypyrazole, 4l	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.7					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18399&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996374	46518474					C03834	ZINC14967894	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32878	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1cccc(Cl)c1)-c1ccc(F)cc1	InChI=1S/C26H29ClFN3O6/c1-15(2)23-24(25(36)29-13-16-4-3-5-17(27)10-16)30-31(19-8-6-18(28)7-9-19)26(23)37-14-21(33)11-20(32)12-22(34)35/h3-10,15,20-21,32-33H,11-14H2,1-2H3,(H,29,36)(H,34,35)/t20-,21+/m1/s1	PUALIFUATFGGNY-RTWAWAEBSA-N	18400	(3R,5S)-6-[(3-{[(3-chlorophenyl)methyl]carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)oxy]-3,5-dihydroxyhexanoic acid::oxypyrazole, 4m	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5.4					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18400&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996372	46518475					C03834	ZINC14967898	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32879	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1ccccc1Cl)-c1ccc(F)cc1	InChI=1S/C26H29ClFN3O6/c1-15(2)23-24(25(36)29-13-16-5-3-4-6-21(16)27)30-31(18-9-7-17(28)8-10-18)26(23)37-14-20(33)11-19(32)12-22(34)35/h3-10,15,19-20,32-33H,11-14H2,1-2H3,(H,29,36)(H,34,35)/t19-,20+/m1/s1	AXWOBMBZJFXJAC-UXHICEINSA-N	18401	(3R,5S)-6-[(3-{[(2-chlorophenyl)methyl]carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)oxy]-3,5-dihydroxyhexanoic acid::oxypyrazole, 4n	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9.5					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18401&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997154	46518476					C03834	ZINC14967902	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32880	CCOc1cccc(CN(C)C(=O)c2nn(c(OC[C@@H](O)C[C@@H](O)CC(O)=O)c2C(C)C)-c2ccc(F)cc2)c1	InChI=1S/C29H36FN3O7/c1-5-39-24-8-6-7-19(13-24)16-32(4)28(38)27-26(18(2)3)29(33(31-27)21-11-9-20(30)10-12-21)40-17-23(35)14-22(34)15-25(36)37/h6-13,18,22-23,34-35H,5,14-17H2,1-4H3,(H,36,37)/t22-,23+/m1/s1	SFOKJHOOHWHHIX-PKTZIBPZSA-N	18402	(3R,5S)-6-[(3-{[(3-ethoxyphenyl)methyl](methyl)carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)oxy]-3,5-dihydroxyhexanoic acid::oxypyrazole, 4o	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 16					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18402&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11995667	46518477					C03834	ZINC14967906	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32881	COc1cc(CN(C)C(=O)c2nn(c(OC[C@@H](O)C[C@@H](O)CC(O)=O)c2C(C)C)-c2ccc(F)cc2)cc(OC)c1	InChI=1S/C29H36FN3O8/c1-17(2)26-27(28(38)32(3)15-18-10-23(39-4)14-24(11-18)40-5)31-33(20-8-6-19(30)7-9-20)29(26)41-16-22(35)12-21(34)13-25(36)37/h6-11,14,17,21-22,34-35H,12-13,15-16H2,1-5H3,(H,36,37)/t21-,22+/m1/s1	ZNAJCIKMRLEKAA-YADHBBJMSA-N	18403	(3R,5S)-6-[(3-{[(3,5-dimethoxyphenyl)methyl](methyl)carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)oxy]-3,5-dihydroxyhexanoic acid::oxypyrazole, 4p	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 43					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18403&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11995666	46518478					C03834	ZINC14967910	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32882	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1cccc(F)c1)-c1ccc(F)cc1	InChI=1S/C27H31F2N3O6/c1-16(2)24-25(26(37)31(3)14-17-5-4-6-19(29)11-17)30-32(20-9-7-18(28)8-10-20)27(24)38-15-22(34)12-21(33)13-23(35)36/h4-11,16,21-22,33-34H,12-15H2,1-3H3,(H,35,36)/t21-,22+/m1/s1	BNRHLGGVKRLQEG-YADHBBJMSA-N	18404	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(3-fluorophenyl)methyl](methyl)carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4q	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 14					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18404&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997440	46518479					C03834	ZINC14967914	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32883	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1cccc(Cl)c1)-c1ccc(F)cc1	InChI=1S/C27H31ClFN3O6/c1-16(2)24-25(26(37)31(3)14-17-5-4-6-18(28)11-17)30-32(20-9-7-19(29)8-10-20)27(24)38-15-22(34)12-21(33)13-23(35)36/h4-11,16,21-22,33-34H,12-15H2,1-3H3,(H,35,36)/t21-,22+/m1/s1	QPHWZVSPNVFKJH-YADHBBJMSA-N	18405	(3R,5S)-6-[(3-{[(3-chlorophenyl)methyl](methyl)carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)oxy]-3,5-dihydroxyhexanoic acid::oxypyrazole, 4r	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8.3					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18405&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997880	46518480					C03834	ZINC14967917	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32884	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1cccc(C)c1)-c1ccc(F)cc1	InChI=1S/C28H34FN3O6/c1-17(2)25-26(27(37)31(4)15-19-7-5-6-18(3)12-19)30-32(21-10-8-20(29)9-11-21)28(25)38-16-23(34)13-22(33)14-24(35)36/h5-12,17,22-23,33-34H,13-16H2,1-4H3,(H,35,36)/t22-,23+/m1/s1	RHTZNQGDXQSHKZ-PKTZIBPZSA-N	18406	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{methyl[(3-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4s	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 37					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18406&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11995665	46518481					C03834	ZINC14967922	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32885	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1cccc(c1)C(F)(F)F)-c1ccc(F)cc1	InChI=1S/C28H31F4N3O6/c1-16(2)24-25(26(40)34(3)14-17-5-4-6-18(11-17)28(30,31)32)33-35(20-9-7-19(29)8-10-20)27(24)41-15-22(37)12-21(36)13-23(38)39/h4-11,16,21-22,36-37H,12-15H2,1-3H3,(H,38,39)/t21-,22+/m1/s1	SLNMZDOWFGQVRY-YADHBBJMSA-N	18407	(3R,5S)-6-{[1-(4-fluorophenyl)-3-[methyl({[3-(trifluoromethyl)phenyl]methyl})carbamoyl]-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4t	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 31					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18407&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11995664	46518482					C03834	ZINC14967926	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32886	COc1cccc(CN(C)C(=O)c2nn(c(OC[C@@H](O)C[C@@H](O)CC(O)=O)c2C(C)C)-c2ccc(F)cc2)c1	InChI=1S/C28H34FN3O7/c1-17(2)25-26(27(37)31(3)15-18-6-5-7-23(12-18)38-4)30-32(20-10-8-19(29)9-11-20)28(25)39-16-22(34)13-21(33)14-24(35)36/h5-12,17,21-22,33-34H,13-16H2,1-4H3,(H,35,36)/t21-,22+/m1/s1	GGHHUYDMLMMLKD-YADHBBJMSA-N	18408	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(3-methoxyphenyl)methyl](methyl)carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4u	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 21					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18408&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997443	46518483					C03834	ZINC14967930	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32887	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1ccc(F)c(F)c1)-c1ccc(F)cc1	InChI=1S/C27H30F3N3O6/c1-15(2)24-25(26(38)32(3)13-16-4-9-21(29)22(30)10-16)31-33(18-7-5-17(28)6-8-18)27(24)39-14-20(35)11-19(34)12-23(36)37/h4-10,15,19-20,34-35H,11-14H2,1-3H3,(H,36,37)/t19-,20+/m1/s1	YQOFXCGHHBKOJH-UXHICEINSA-N	18409	(3R,5S)-6-[(3-{[(3,4-difluorophenyl)methyl](methyl)carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)oxy]-3,5-dihydroxyhexanoic acid::oxypyrazole, 4v	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5.7							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18409&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997881	46518484					C03834	ZINC14967934	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32888	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1ccccc1F)-c1ccc(F)cc1	InChI=1S/C27H31F2N3O6/c1-16(2)24-25(26(37)31(3)14-17-6-4-5-7-22(17)29)30-32(19-10-8-18(28)9-11-19)27(24)38-15-21(34)12-20(33)13-23(35)36/h4-11,16,20-21,33-34H,12-15H2,1-3H3,(H,35,36)/t20-,21+/m1/s1	HQTDHJQRDITCKI-RTWAWAEBSA-N	18410	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(2-fluorophenyl)methyl](methyl)carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4w	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8.7							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18410&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997303	46518485					C03834	ZINC14967938	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32889	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1ccc(F)cc1)-c1ccc(F)cc1	InChI=1S/C27H31F2N3O6/c1-16(2)24-25(26(37)31(3)14-17-4-6-18(28)7-5-17)30-32(20-10-8-19(29)9-11-20)27(24)38-15-22(34)12-21(33)13-23(35)36/h4-11,16,21-22,33-34H,12-15H2,1-3H3,(H,35,36)/t21-,22+/m1/s1	WTJOYWFUYQGCLE-YADHBBJMSA-N	18411	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(4-fluorophenyl)methyl](methyl)carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4x	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 18							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18411&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997441	46518486					C03834	ZINC14967943	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32890	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)[C@H](C)c1ccccc1)-c1ccc(F)cc1	InChI=1S/C28H34FN3O6/c1-17(2)25-26(27(37)31(4)18(3)19-8-6-5-7-9-19)30-32(21-12-10-20(29)11-13-21)28(25)38-16-23(34)14-22(33)15-24(35)36/h5-13,17-18,22-23,33-34H,14-16H2,1-4H3,(H,35,36)/t18-,22-,23+/m1/s1	RLLOSQNXGYIGTB-YSZBQJHXSA-N	18412	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{methyl[(1R)-1-phenylethyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4y	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 21							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18412&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997445	46518487					C03834	ZINC14967947	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32891	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCCc1ccccc1)-c1ccc(F)cc1	InChI=1S/C27H32FN3O6/c1-17(2)24-25(26(36)29-13-12-18-6-4-3-5-7-18)30-31(20-10-8-19(28)9-11-20)27(24)37-16-22(33)14-21(32)15-23(34)35/h3-11,17,21-22,32-33H,12-16H2,1-2H3,(H,29,36)(H,34,35)/t21-,22+/m1/s1	YIUGYUCTBRGVMO-YADHBBJMSA-N	18413	(3R,5S)-6-{[1-(4-fluorophenyl)-3-[(2-phenylethyl)carbamoyl]-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4z	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18413&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996683	46518488					C03834	ZINC14967951	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32892	CCN(Cc1ccccc1)C(=O)c1nn(c(OC[C@@H](O)C[C@@H](O)CC(O)=O)c1C(C)C)-c1ccc(F)cc1	InChI=1S/C28H34FN3O6/c1-4-31(16-19-8-6-5-7-9-19)27(37)26-25(18(2)3)28(32(30-26)21-12-10-20(29)11-13-21)38-17-23(34)14-22(33)15-24(35)36/h5-13,18,22-23,33-34H,4,14-17H2,1-3H3,(H,35,36)/t22-,23+/m1/s1	DTJSSFGAPFKCJU-PKTZIBPZSA-N	18414	(3R,5S)-6-({3-[benzyl(ethyl)carbamoyl]-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl}oxy)-3,5-dihydroxyhexanoic acid::oxypyrazole, 4aa	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 14							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18414&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997302	46518489					C03834	ZINC14967955	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32893	CC(C)c1c(nn(c1OC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccc(F)cc1)C(=O)NCC1CCCCC1	InChI=1S/C26H36FN3O6/c1-16(2)23-24(25(35)28-14-17-6-4-3-5-7-17)29-30(19-10-8-18(27)9-11-19)26(23)36-15-21(32)12-20(31)13-22(33)34/h8-11,16-17,20-21,31-32H,3-7,12-15H2,1-2H3,(H,28,35)(H,33,34)/t20-,21+/m1/s1	WGQVBDKLKFLECV-RTWAWAEBSA-N	18415	(3R,5S)-6-({3-[(cyclohexylmethyl)carbamoyl]-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl}oxy)-3,5-dihydroxyhexanoic acid::oxypyrazole, 4bb	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 17							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18415&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23648004	46518490					C03834	ZINC14967959	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32894	CCCCNC(=O)c1nn(c(OC[C@@H](O)C[C@@H](O)CC(O)=O)c1C(C)C)-c1ccc(F)cc1	InChI=1S/C23H32FN3O6/c1-4-5-10-25-22(32)21-20(14(2)3)23(27(26-21)16-8-6-15(24)7-9-16)33-13-18(29)11-17(28)12-19(30)31/h6-9,14,17-18,28-29H,4-5,10-13H2,1-3H3,(H,25,32)(H,30,31)/t17-,18+/m1/s1	XOBBTLVBHHPPRH-MSOLQXFVSA-N	18416	(3R,5S)-6-{[3-(butylcarbamoyl)-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4cc	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 76							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18416&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997155	46518491					C03834	ZINC14967962	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32895	CC(C)c1c(nn(c1OC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccc(F)cc1)C(=O)N(C)CC1CCCCC1	InChI=1S/C27H38FN3O6/c1-17(2)24-25(26(36)30(3)15-18-7-5-4-6-8-18)29-31(20-11-9-19(28)10-12-20)27(24)37-16-22(33)13-21(32)14-23(34)35/h9-12,17-18,21-22,32-33H,4-8,13-16H2,1-3H3,(H,34,35)/t21-,22+/m1/s1	LEEKGUHBAWHKQS-YADHBBJMSA-N	18417	(3R,5S)-6-({3-[(cyclohexylmethyl)(methyl)carbamoyl]-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl}oxy)-3,5-dihydroxyhexanoic acid::oxypyrazole, 4dd	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.2							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18417&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11995663	46518492					C03834	ZINC14967966	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32896	CC(C)c1c(nn(c1OC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccc(F)cc1)C(=O)N1CCCC1c1ccccc1	InChI=1S/C29H34FN3O6/c1-18(2)26-27(28(38)32-14-6-9-24(32)19-7-4-3-5-8-19)31-33(21-12-10-20(30)11-13-21)29(26)39-17-23(35)15-22(34)16-25(36)37/h3-5,7-8,10-13,18,22-24,34-35H,6,9,14-17H2,1-2H3,(H,36,37)/t22-,23+,24?/m1/s1	VSKOZURXNCTEIB-NHIDMIJISA-N	18418	(3R,5S)-6-{[1-(4-fluorophenyl)-3-[(2-phenylpyrrolidin-1-yl)carbonyl]-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4ee	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 14							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18418&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23648005	46518493					C03834	ZINC14967973	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32897	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N1CCc2ccccc2C1)-c1ccc(F)cc1	InChI=1S/C28H32FN3O6/c1-17(2)25-26(27(37)31-12-11-18-5-3-4-6-19(18)15-31)30-32(21-9-7-20(29)8-10-21)28(25)38-16-23(34)13-22(33)14-24(35)36/h3-10,17,22-23,33-34H,11-16H2,1-2H3,(H,35,36)/t22-,23+/m1/s1	KKERRCWFTMXHDI-PKTZIBPZSA-N	18419	(3R,5S)-6-{[1-(4-fluorophenyl)-4-(propan-2-yl)-3-(1,2,3,4-tetrahydroisoquinolin-2-ylcarbonyl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4ff	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18419&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997589	46518494					C03834	ZINC14967982	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32898	CC(C)c1c(nn(c1OC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccc(F)cc1)C(=O)N1CCC[C@@H](C1)c1ccccc1	InChI=1S/C30H36FN3O6/c1-19(2)27-28(29(39)33-14-6-9-21(17-33)20-7-4-3-5-8-20)32-34(23-12-10-22(31)11-13-23)30(27)40-18-25(36)15-24(35)16-26(37)38/h3-5,7-8,10-13,19,21,24-25,35-36H,6,9,14-18H2,1-2H3,(H,37,38)/t21-,24+,25-/m0/s1	IOHTZUKUZYDMQM-GPUOULLFSA-N	18420	(3R,5S)-6-{[1-(4-fluorophenyl)-3-{[(3R)-3-phenylpiperidin-1-yl]carbonyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4gg	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.8							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18420&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23648006	46518495					C03834	ZINC14967988	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32899	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N1CCCCC1)-c1ccc(F)cc1	InChI=1S/C24H32FN3O6/c1-15(2)21-22(23(33)27-10-4-3-5-11-27)26-28(17-8-6-16(25)7-9-17)24(21)34-14-19(30)12-18(29)13-20(31)32/h6-9,15,18-19,29-30H,3-5,10-14H2,1-2H3,(H,31,32)/t18-,19+/m1/s1	AMPPAPYNHBKNHM-MOPGFXCFSA-N	18421	(3R,5S)-6-{[1-(4-fluorophenyl)-3-(piperidin-1-ylcarbonyl)-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4hh	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 47							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18421&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11997735	46518496					C03834	ZINC14967992	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32900	CC(C)c1c(OC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1ccccn1)-c1ccc(F)cc1	InChI=1S/C25H29FN4O6/c1-15(2)22-23(24(35)28-13-17-5-3-4-10-27-17)29-30(18-8-6-16(26)7-9-18)25(22)36-14-20(32)11-19(31)12-21(33)34/h3-10,15,19-20,31-32H,11-14H2,1-2H3,(H,28,35)(H,33,34)/t19-,20+/m1/s1	SAGUSTWFTAGTFV-UXHICEINSA-N	18422	(3R,5S)-6-{[1-(4-fluorophenyl)-4-(propan-2-yl)-3-[(pyridin-2-ylmethyl)carbamoyl]-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4ii	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18422&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23648007	46518497					C03834	ZINC14967996	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32901	COCc1cccc(CNC(=O)c2nn(c(OC[C@@H](O)C[C@@H](O)CC(O)=O)c2C(C)C)-c2ccc(F)cc2)c1	InChI=1S/C28H34FN3O7/c1-17(2)25-26(27(37)30-14-18-5-4-6-19(11-18)15-38-3)31-32(21-9-7-20(29)8-10-21)28(25)39-16-23(34)12-22(33)13-24(35)36/h4-11,17,22-23,33-34H,12-16H2,1-3H3,(H,30,37)(H,35,36)/t22-,23+/m1/s1	HRMPDLKLCHFEFH-PKTZIBPZSA-N	18423	(3R,5S)-6-{[1-(4-fluorophenyl)-3-({[3-(methoxymethyl)phenyl]methyl}carbamoyl)-4-(propan-2-yl)-1H-pyrazol-5-yl]oxy}-3,5-dihydroxyhexanoic acid::oxypyrazole, 4jj	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 31							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18423&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11996524	46518498					C03834	ZINC14967999	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32902	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1ccccc1)-c1ccc(F)cc1	InChI=1S/C28H34FN3O5/c1-18(2)26-24(14-13-22(33)15-23(34)16-25(35)36)32(21-11-9-20(29)10-12-21)30-27(26)28(37)31(3)17-19-7-5-4-6-8-19/h4-12,18,22-23,33-34H,13-17H2,1-3H3,(H,35,36)/t22-,23-/m1/s1	NKXSDKKNJJYOFA-DHIUTWEWSA-N	18424	(3R,5R)-7-{3-[benzyl(methyl)carbamoyl]-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl}-3,5-dihydroxyheptanoic acid::pyrazole, 3b	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.2							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18424&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11540777	46518499					C03834	ZINC14968003	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32903	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1ccc(C)cc1)-c1ccc(F)cc1	InChI=1S/C28H34FN3O5/c1-17(2)26-24(13-12-22(33)14-23(34)15-25(35)36)32(21-10-8-20(29)9-11-21)31-27(26)28(37)30-16-19-6-4-18(3)5-7-19/h4-11,17,22-23,33-34H,12-16H2,1-3H3,(H,30,37)(H,35,36)/t22-,23-/m1/s1	LRVVTOGAGAXSRZ-DHIUTWEWSA-N	18425	(3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid::pyrazole, 3f	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.5							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18425&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11562549	46518500					C03834	ZINC14968008	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32904	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N(C)Cc1cccc(F)c1)-c1ccc(F)cc1	InChI=1S/C28H33F2N3O5/c1-17(2)26-24(12-11-22(34)14-23(35)15-25(36)37)33(21-9-7-19(29)8-10-21)31-27(26)28(38)32(3)16-18-5-4-6-20(30)13-18/h4-10,13,17,22-23,34-35H,11-12,14-16H2,1-3H3,(H,36,37)/t22-,23-/m1/s1	OQAJLGZZINRLJK-DHIUTWEWSA-N	18426	(3R,5R)-7-[1-(4-fluorophenyl)-3-{[(3-fluorophenyl)methyl](methyl)carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid::pyrazole, 3q	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.1							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18426&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11570032	46518501					C03834	ZINC14968012	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32905	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)N1CCC[C@@H](C1)c1ccccc1)-c1ccc(F)cc1	InChI=1S/C31H38FN3O5/c1-20(2)29-27(15-14-25(36)17-26(37)18-28(38)39)35(24-12-10-23(32)11-13-24)33-30(29)31(40)34-16-6-9-22(19-34)21-7-4-3-5-8-21/h3-5,7-8,10-13,20,22,25-26,36-37H,6,9,14-19H2,1-2H3,(H,38,39)/t22-,25+,26+/m0/s1	YLAVHPQPEFUCRY-HDYLNDSGSA-N	18427	(3R,5R)-7-[1-(4-fluorophenyl)-3-{[(3R)-3-phenylpiperidin-1-yl]carbonyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid::pyrazole, 3gg	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.1							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18427&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23648008	46518502					C03834	ZINC14968016	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32906	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O	InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1	BPRHUIZQVSMCRT-VEUZHWNKSA-N	18372	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::CHEMBL1496::Ros::Rosuvastatin::US9102656, Rosuvastatin ::ZD4522	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.1							Curated from the literature by BindingDB	10.1016/j.bmcl.2007.08.004	10.7270/Q2ZS2TS7	17764936	aid1797731		Larsen, SD; Poel, TJ; Filipski, KJ; Kohrt, JT; Pfefferkorn, JA; Sorenson, RJ; Tait, BD; Askew, V; Dillon, L; Hanselman, JC; Lu, GH; Robertson, A; Sekerke, C; Kowala, MC; Auerbach, BJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18372&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search		1HWL	446157	46518448	38545	CHEMBL1496	DB01098	2989	C03834	ZINC01535101	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
32863	CCn1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)c1C(N)=O)-c1ccc(F)cc1	InChI=1S/C21H27FN2O5/c1-3-24-17(9-8-15(25)10-16(26)11-18(27)28)19(12(2)20(24)21(23)29)13-4-6-14(22)7-5-13/h4-7,15-16,25-26H,3,8-11H2,1-2H3,(H2,23,29)(H,27,28)/p-1/t15-,16-/m1/s1	IQPSYQCIJNTPBS-HZPDHXFCSA-M	18385	Alkyl substituted pyrrole compound, 29a::sodium (3R,5R)-7-[5-carbamoyl-1-ethyl-3-(4-fluorophenyl)-4-methyl-1H-pyrrol-2-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30					7.2	37.00 C	Curated from the literature by BindingDB	10.1016/j.bmc.2007.05.031	10.7270/Q23J3B7G	17560788	aid1797730		Bratton, LD; Auerbach, B; Choi, C; Dillon, L; Hanselman, JC; Larsen, SD; Lu, G; Olsen, K; Pfefferkorn, JA; Robertson, A; Sekerke, C; Trivedi, BK; Unangst, PC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18385&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91895922	46518460					C03834	ZINC14967840	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40091	CC(C)c1nc(Nc2nsc(n2)-c2ccccc2)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O	InChI=1S/C28H28FN5O4S/c1-16(2)24-22(13-12-20(35)14-21(36)15-23(37)38)25(17-8-10-19(29)11-9-17)31-27(30-24)33-28-32-26(39-34-28)18-6-4-3-5-7-18/h3-13,16,20-21,35-36H,14-15H2,1-2H3,(H,37,38)(H,30,31,33,34)/b13-12+/t20-,21-/m1/s1	MHPTUGAUOGKAGG-DDVDASKDSA-N	22146	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(5-phenyl-1,2,4-thiadiazol-3-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[(5-phenyl-1,2,4-thiadiazol-3-yl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid::thiadiazole compound, 8a	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.9		 7.7			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22146&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825301	49845961					C03834	ZINC14978005	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40092	CC(C)c1nc(Nc2ccon2)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O	InChI=1S/C23H25FN4O5/c1-13(2)21-18(8-7-16(29)11-17(30)12-20(31)32)22(14-3-5-15(24)6-4-14)27-23(26-21)25-19-9-10-33-28-19/h3-10,13,16-17,29-30H,11-12H2,1-2H3,(H,31,32)(H,25,26,27,28)/b8-7+/t16-,17-/m1/s1	KTZCMSGWDSHEMY-NXVGNOFTSA-N	22147	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(1,2-oxazol-3-ylamino)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(isoxazol-3-ylamino)-6-(1-methylethyl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::isoxazole compound, 9a	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.3		 1.4			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22147&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825302	49845962					C03834	ZINC14978008	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40093	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)c1ccon1	InChI=1S/C24H27FN4O5/c1-14(2)22-19(9-8-17(30)12-18(31)13-21(32)33)23(15-4-6-16(25)7-5-15)27-24(26-22)29(3)20-10-11-34-28-20/h4-11,14,17-18,30-31H,12-13H2,1-3H3,(H,32,33)/b9-8+/t17-,18-/m1/s1	LFEYVBFPQIDHLO-RKQNLGICSA-N	22148	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1,2-oxazol-3-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::isoxazole compound, 9b	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.0		 9			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22148&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825303	49845963					C03834	ZINC14978011	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40094	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(c1ccon1)S(C)(=O)=O	InChI=1S/C24H27FN4O7S/c1-14(2)22-19(9-8-17(30)12-18(31)13-21(32)33)23(15-4-6-16(25)7-5-15)27-24(26-22)29(37(3,34)35)20-10-11-36-28-20/h4-11,14,17-18,30-31H,12-13H2,1-3H3,(H,32,33)/b9-8+/t17-,18-/m1/s1	UWDARGZAWVSXKW-RKQNLGICSA-N	22149	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(1,2-oxazol-3-yl)methanesulfonamido]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::isoxazole compound, 9c	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 33		 5.5			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22149	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22149&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825304	49845964					C03834	ZINC14978013	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40095	CC(C)c1nc(Nc2ccnn2C)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O	InChI=1S/C24H28FN5O4/c1-14(2)22-19(9-8-17(31)12-18(32)13-21(33)34)23(15-4-6-16(25)7-5-15)29-24(28-22)27-20-10-11-26-30(20)3/h4-11,14,17-18,31-32H,12-13H2,1-3H3,(H,33,34)(H,27,28,29)/b9-8+/t17-,18-/m1/s1	HTZWJTVTVPEQRH-RKQNLGICSA-N	22150	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(1-methyl-1H-pyrazol-5-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::pyrazole compound, 10a	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.4		 1.3			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22150&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825305	49845965					C03834	ZINC14978016	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40096	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)c1ccnn1C	InChI=1S/C25H30FN5O4/c1-15(2)23-20(10-9-18(32)13-19(33)14-22(34)35)24(16-5-7-17(26)8-6-16)29-25(28-23)30(3)21-11-12-27-31(21)4/h5-12,15,18-19,32-33H,13-14H2,1-4H3,(H,34,35)/b10-9+/t18-,19-/m1/s1	ZKWRHEKGCMPVDD-BGGMYYEUSA-N	22151	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1-methyl-1H-pyrazol-5-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::pyrazole compound, 10b	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.5		 2.5			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22151	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22151&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825306	49845966					C03834	ZINC14978019	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40097	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(c1ccnn1C)S(C)(=O)=O	InChI=1S/C25H30FN5O6S/c1-15(2)23-20(10-9-18(32)13-19(33)14-22(34)35)24(16-5-7-17(26)8-6-16)29-25(28-23)31(38(4,36)37)21-11-12-27-30(21)3/h5-12,15,18-19,32-33H,13-14H2,1-4H3,(H,34,35)/b10-9+/t18-,19-/m1/s1	OSFSOCAXXXFKCI-BGGMYYEUSA-N	22152	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(1-methyl-1H-pyrazol-5-yl)methanesulfonamido]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[(1-methyl-1H-pyrazol-5-yl)(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid::pyrazole compound, 10c	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.2		 5.4			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22152&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825307	49845967					C03834	ZINC14978022	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40098	CC(C)c1nc(Nc2cc(nn2C)C(C)(C)C)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O	InChI=1S/C28H36FN5O4/c1-16(2)25-21(12-11-19(35)13-20(36)14-24(37)38)26(17-7-9-18(29)10-8-17)32-27(31-25)30-23-15-22(28(3,4)5)33-34(23)6/h7-12,15-16,19-20,35-36H,13-14H2,1-6H3,(H,37,38)(H,30,31,32)/b12-11+/t19-,20-/m1/s1	OHTJDABXTNGMCT-XICOBVEKSA-N	22153	(3R,5S,6E)-7-{2-[(3-tert-butyl-1-methyl-1H-pyrazol-5-yl)amino]-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid::pyrazole compound, 11a	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12.4		 1.9			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22153	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22153&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825308	49845968					C03834	ZINC14978025	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40099	CC(C)c1nc(Nc2ccn(C)n2)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O	InChI=1S/C24H28FN5O4/c1-14(2)22-19(9-8-17(31)12-18(32)13-21(33)34)23(15-4-6-16(25)7-5-15)28-24(27-22)26-20-10-11-30(3)29-20/h4-11,14,17-18,31-32H,12-13H2,1-3H3,(H,33,34)(H,26,27,28,29)/b9-8+/t17-,18-/m1/s1	WJKPEOOFIOXKEA-RKQNLGICSA-N	22154	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(1-methyl-1H-pyrazol-3-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::pyrazole compound, 12a	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.8		 3.7			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22154&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825309	49845969					C03834	ZINC14978028	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40100	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)c1ccn(C)n1	InChI=1S/C25H30FN5O4/c1-15(2)23-20(10-9-18(32)13-19(33)14-22(34)35)24(16-5-7-17(26)8-6-16)28-25(27-23)31(4)21-11-12-30(3)29-21/h5-12,15,18-19,32-33H,13-14H2,1-4H3,(H,34,35)/b10-9+/t18-,19-/m1/s1	MWAAOCBADJGDMI-BGGMYYEUSA-N	22155	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1-methyl-1H-pyrazol-3-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::pyrazole compound, 12b	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.5		 1.2			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22155	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22155&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825310	49845970					C03834	ZINC14978031	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40101	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(c1ccn(C)n1)S(C)(=O)=O	InChI=1S/C25H30FN5O6S/c1-15(2)23-20(10-9-18(32)13-19(33)14-22(34)35)24(16-5-7-17(26)8-6-16)28-25(27-23)31(38(4,36)37)21-11-12-30(3)29-21/h5-12,15,18-19,32-33H,13-14H2,1-4H3,(H,34,35)/b10-9+/t18-,19-/m1/s1	CQQSHHILLHFILU-BGGMYYEUSA-N	22156	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(1-methyl-1H-pyrazol-3-yl)methanesulfonamido]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::pyrazole compound, 12c	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.7		 7.7			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22156	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22156&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825311	49845971					C03834	ZINC14978033	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40102	CC(C)c1nc(Nc2nnnn2C)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O	InChI=1S/C22H26FN7O4/c1-12(2)19-17(9-8-15(31)10-16(32)11-18(33)34)20(13-4-6-14(23)7-5-13)25-21(24-19)26-22-27-28-29-30(22)3/h4-9,12,15-16,31-32H,10-11H2,1-3H3,(H,33,34)(H,24,25,26,27,29)/b9-8+/t15-,16-/m1/s1	OWGDGUYWLUBIIC-GUFYHEMZSA-N	22157	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::tetrazole compound, 13a	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 0.9		 1.5			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22157	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22157&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825312	49845972					C03834	ZINC14978036	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40103	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)c1nnnn1C	InChI=1S/C23H28FN7O4/c1-13(2)20-18(10-9-16(32)11-17(33)12-19(34)35)21(14-5-7-15(24)8-6-14)26-22(25-20)30(3)23-27-28-29-31(23)4/h5-10,13,16-17,32-33H,11-12H2,1-4H3,(H,34,35)/b10-9+/t16-,17-/m1/s1	KOTLFRFIWUOROR-VEUZHWNKSA-N	22158	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1-methyl-1H-1,2,3,4-tetrazol-5-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::tetrazole compound, 13b	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 0.5		 1.4			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22158	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22158&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825313	49845973					C03834	ZINC14978039	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40104	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(c1nnnn1C)S(C)(=O)=O	InChI=1S/C23H28FN7O6S/c1-13(2)20-18(10-9-16(32)11-17(33)12-19(34)35)21(14-5-7-15(24)8-6-14)26-22(25-20)31(38(4,36)37)23-27-28-29-30(23)3/h5-10,13,16-17,32-33H,11-12H2,1-4H3,(H,34,35)/b10-9+/t16-,17-/m1/s1	UJHJIOUQRVUYNN-VEUZHWNKSA-N	22159	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(1-methyl-1H-1,2,3,4-tetrazol-5-yl)methanesulfonamido]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::(3R,5S,6E)-7-{4-(4-fluorophenyl)-6-(1-methylethyl)-2-[(methylsulfonyl)(1-methyl-1H-tetrazol-5-yl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid::tetrazole compound, 13c	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.2		 1.0			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22159	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22159&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825314	49845974					C03834	ZINC14978042	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40105	CC(C)c1nc(Nc2cc(nn2C)C(O)=O)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O	InChI=1S/C25H28FN5O6/c1-13(2)22-18(9-8-16(32)10-17(33)11-21(34)35)23(14-4-6-15(26)7-5-14)29-25(28-22)27-20-12-19(24(36)37)30-31(20)3/h4-9,12-13,16-17,32-33H,10-11H2,1-3H3,(H,34,35)(H,36,37)(H,27,28,29)/b9-8+/t16-,17-/m1/s1	FHALQUHVYPUUQM-PIIXRYACSA-N	22160	pyrazole compound, 14a::sodium 5-({5-[(1E,3S,5R)-6-carboxy-3,5-dihydroxyhex-1-en-1-yl]-4-(4-fluorophenyl)-6-(1-methylethyl)pyrimidin-2-yl}amino)-1-methyl-1H-pyrazole-3-carboxylate::sodium 5-({5-[(1E,3S,5R)-6-carboxy-3,5-dihydroxyhex-1-en-1-yl]-4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-2-yl}amino)-1-methyl-1H-pyrazole-3-carboxylate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 0.9		 13.7			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22160	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22160&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825315	49845975					C03834	ZINC14978044	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40106	CC(C)c1nc(Nc2ncnn2C)nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O	InChI=1S/C23H27FN6O4/c1-13(2)20-18(9-8-16(31)10-17(32)11-19(33)34)21(14-4-6-15(24)7-5-14)28-22(27-20)29-23-25-12-26-30(23)3/h4-9,12-13,16-17,31-32H,10-11H2,1-3H3,(H,33,34)(H,25,26,27,28,29)/b9-8+/t16-,17-/m1/s1	NZKSPBPEBDVMFK-PIIXRYACSA-N	22161	sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[(1-methyl-1H-1,2,4-triazol-5-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate::triazole compound, 1a	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3		 3.7			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22161	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22161&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825316	49845976					C03834	ZINC14978047	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40107	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(c1ncnn1C)S(C)(=O)=O	InChI=1S/C24H29FN6O6S/c1-14(2)21-19(10-9-17(32)11-18(33)12-20(34)35)22(15-5-7-16(25)8-6-15)29-23(28-21)31(38(4,36)37)24-26-13-27-30(24)3/h5-10,13-14,17-18,32-33H,11-12H2,1-4H3,(H,34,35)/b10-9+/t17-,18-/m1/s1	XDXJFEXLMAVNBO-AQRBRUGDSA-N	22162	sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[N-(1-methyl-1H-1,2,4-triazol-5-yl)methanesulfonamido]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate::triazole compound, 1c	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.9		 7.5			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22162&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24825317	49845977					C03834	ZINC14978050	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40108	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)c1ncnn1C	InChI=1S/C24H29FN6O4/c1-14(2)21-19(10-9-17(32)11-18(33)12-20(34)35)22(15-5-7-16(25)8-6-15)29-23(28-21)30(3)24-26-13-27-31(24)4/h5-10,13-14,17-18,32-33H,11-12H2,1-4H3,(H,34,35)/b10-9+/t17-,18-/m1/s1	QAMJBKXUQQOLPQ-AQRBRUGDSA-N	22163	BMS-644950::sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(1-methyl-1H-1,2,4-triazol-5-yl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate::triazole compound, 1b	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.4		 3.95			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22163&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24809501	49845978					C03834	ZINC14978053	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40109	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccccc1	InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1	XUKUURHRXDUEBC-KAYWLYCHSA-N	22164	(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid::(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid::Atorvastatin::CHEMBL1487::CI 981::Lipitor::US9353061, Atorvastatina	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.2		 2.5			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22164&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	117	1HWK	60823	49845979	39548	CHEMBL1487		2949	C06834	ZINC03920719	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40110	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O	InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1	BPRHUIZQVSMCRT-VEUZHWNKSA-N	18372	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::CHEMBL1496::Ros::Rosuvastatin::US9102656, Rosuvastatin ::ZD4522	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.1		 0.6			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18372&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search		1HWL	446157	46518448	38545	CHEMBL1496	DB01098	2989	C03834	ZINC01535101	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40111	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12	InChI=1S/C25H40O6/c1-6-25(4,5)24(30)31-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-18(26)13-19(27)14-22(28)29/h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29)/t15-,16-,18+,19+,20-,21-,23-/m0/s1	XWLXKKNPFMNSFA-HGQWONQESA-N	18375	(3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid::Simvastatin::Simvastatin acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.3		 6.2			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18375&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	SIM	4XW2,1HW9,6KJF,3HLF	64718	46518450					C03834	ZINC03833877	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40112	COCc1c(nc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)c1-c1ccc(F)cc1)C(C)C	InChI=1S/C26H34FNO5/c1-15(2)25-21(11-10-19(29)12-20(30)13-23(31)32)24(17-6-8-18(27)9-7-17)22(14-33-5)26(28-25)16(3)4/h6-11,15-16,19-20,29-30H,12-14H2,1-5H3,(H,31,32)/b11-10+/t19-,20-/m1/s1	SEERZIQQUAZTOL-ANMDKAQQSA-N	18376	(3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid::Cerivastatin::cid_446156	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9.8		 2.3			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18376&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search		1HWJ	446156	46518451	3558		DB00439	2950	C03834	ZINC11330186	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
40113	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12	InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1	TUZYXOIXSAXUGO-PZAWKZKUSA-N	20688	(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid::CHEMBL1144::Pravastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 31.6		 29			7	37.00 C	Curated from the literature by BindingDB	10.1021/jm800001n	10.7270/Q2FT8JB2	18412317	aid1798163		Ahmad, S; Madsen, CS; Stein, PD; Janovitz, E; Huang, C; Ngu, K; Bisaha, S; Kennedy, LJ; Chen, BC; Zhao, R; Sitkoff, D; Monshizadegan, H; Yin, X; Ryan, CS; Zhang, R; Giancarli, M; Bird, E; Chang, M; Chen, X; Setters, R; Search, D; Zhuang, S; Nguyen-Tran, V; Cuff, CA; Harrity, T; Darienzo, CJ; Li, T; Reeves, RA; Blanar, MA; Barrish, JC; Zahler, R; Robl, JA	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20688&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			54687	49688762	63618	CHEMBL1144	DB00175	2953	C01844	ZINC03798763	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37435	COCc1c(nc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)c1-c1ccc(F)cc1)C(C)C	InChI=1S/C26H34FNO5/c1-15(2)25-21(11-10-19(29)12-20(30)13-23(31)32)24(17-6-8-18(27)9-7-17)22(14-33-5)26(28-25)16(3)4/h6-11,15-16,19-20,29-30H,12-14H2,1-5H3,(H,31,32)/b11-10+/t19-,20-/m1/s1	SEERZIQQUAZTOL-ANMDKAQQSA-N	18376	(3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-bis(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoic acid::Cerivastatin::cid_446156	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.8		 1.7			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18376&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search		1HWJ	446156	46518451	3558		DB00439	2950	C03834	ZINC11330186	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37436	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12	InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1	TUZYXOIXSAXUGO-PZAWKZKUSA-N	20688	(3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid::CHEMBL1144::Pravastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13		 17			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20688&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			54687	49688762	63618	CHEMBL1144	DB00175	2953	C01844	ZINC03798763	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37437	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O	InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1	BPRHUIZQVSMCRT-VEUZHWNKSA-N	18372	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::CHEMBL1496::Ros::Rosuvastatin::US9102656, Rosuvastatin ::ZD4522	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.1		 0.3			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18372&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search		1HWL	446157	46518448	38545	CHEMBL1496	DB01098	2989	C03834	ZINC01535101	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37438	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1ccccc1)-c1ccc(F)cc1	InChI=1S/C27H32FN3O5/c1-17(2)25-23(13-12-21(32)14-22(33)15-24(34)35)31(20-10-8-19(28)9-11-20)30-26(25)27(36)29-16-18-6-4-3-5-7-18/h3-11,17,21-22,32-33H,12-16H2,1-2H3,(H,29,36)(H,34,35)/t21-,22-/m1/s1	DEJDBOMWUVPBEO-FGZHOGPDSA-N	20689	(3R,5R)-7-[3-(benzylcarbamoyl)-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid::pyrazole-based inhibitor, 2	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.7		 0.3			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20689&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11612974	49688763					C03834	ZINC14974326	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37439	COc1ccc(CNC(=O)c2nn(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C(C)C)-c2ccc(F)cc2)cc1	InChI=1S/C28H34FN3O6/c1-17(2)26-24(13-10-21(33)14-22(34)15-25(35)36)32(20-8-6-19(29)7-9-20)31-27(26)28(37)30-16-18-4-11-23(38-3)12-5-18/h4-9,11-12,17,21-22,33-34H,10,13-16H2,1-3H3,(H,30,37)(H,35,36)/p-1/t21-,22-/m1/s1	VWXFVVDQBRERFE-FGZHOGPDSA-M	20690	pyrazole-based inhibitor, 33::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-methoxyphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.8		 0.4			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20690&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831933	49688764					C03834	ZINC14974329	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37440	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)NCc1ccc(F)cc1)-c1ccc(F)cc1	InChI=1S/C27H31F2N3O5/c1-16(2)25-23(12-11-21(33)13-22(34)14-24(35)36)32(20-9-7-19(29)8-10-20)31-26(25)27(37)30-15-17-3-5-18(28)6-4-17/h3-10,16,21-22,33-34H,11-15H2,1-2H3,(H,30,37)(H,35,36)/p-1/t21-,22-/m1/s1	RGTFLCOJZZNQIJ-FGZHOGPDSA-M	20691	pyrazole-based inhibitor, 34::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-fluorophenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.8		 0.7			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20691&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59832007	49688765					C03834	ZINC14974332	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37441	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)NCc1ccc(C)cc1)-c1ccc(F)cc1	InChI=1S/C28H34FN3O5/c1-17(2)26-24(13-12-22(33)14-23(34)15-25(35)36)32(21-10-8-20(29)9-11-21)31-27(26)28(37)30-16-19-6-4-18(3)5-7-19/h4-11,17,22-23,33-34H,12-16H2,1-3H3,(H,30,37)(H,35,36)/p-1/t22-,23-/m1/s1	LRVVTOGAGAXSRZ-DHIUTWEWSA-M	20692	PF-3052334::pyrazole-based inhibitor, 35::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.9		 0.9			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20692&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59832001	49688766					C03834	ZINC14968008	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37442	COCc1cccc(CNC(=O)c2nn(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C(C)C)-c2ccc(F)cc2)c1	InChI=1S/C29H36FN3O6/c1-18(2)27-25(12-11-23(34)14-24(35)15-26(36)37)33(22-9-7-21(30)8-10-22)32-28(27)29(38)31-16-19-5-4-6-20(13-19)17-39-3/h4-10,13,18,23-24,34-35H,11-12,14-17H2,1-3H3,(H,31,38)(H,36,37)/p-1/t23-,24-/m1/s1	WQAAILYANIAJRP-DNQXCXABSA-M	20693	pyrazole-based inhibitor, 36::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-({[3-(methoxymethyl)phenyl]methyl}carbamoyl)-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.0		 0.7			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20693&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59832050	49688767					C03834	ZINC14974335	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37443	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)NCc1cccc(c1)C#N)-c1ccc(F)cc1	InChI=1S/C28H31FN4O5/c1-17(2)26-24(11-10-22(34)13-23(35)14-25(36)37)33(21-8-6-20(29)7-9-21)32-27(26)28(38)31-16-19-5-3-4-18(12-19)15-30/h3-9,12,17,22-23,34-35H,10-11,13-14,16H2,1-2H3,(H,31,38)(H,36,37)/p-1/t22-,23-/m1/s1	YJOXUBMEMQKAPY-DHIUTWEWSA-M	20694	pyrazole-based inhibitor, 37::sodium (3R,5R)-7-(3-{[(3-cyanophenyl)methyl]carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.2		 1.4			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20694&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91895932	49688768					C03834	ZINC14974338	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37444	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)NCc1ccc(cc1)C(=O)N(C)C)-c1ccc(F)cc1	InChI=1S/C30H37FN4O6/c1-18(2)27-25(14-13-23(36)15-24(37)16-26(38)39)35(22-11-9-21(31)10-12-22)33-28(27)29(40)32-17-19-5-7-20(8-6-19)30(41)34(3)4/h5-12,18,23-24,36-37H,13-17H2,1-4H3,(H,32,40)(H,38,39)/p-1/t23-,24-/m1/s1	NRHMUVWUITXZFM-DNQXCXABSA-M	20695	pyrazole-based inhibitor, 38::sodium (3R,5R)-7-[3-({[4-(dimethylcarbamoyl)phenyl]methyl}carbamoyl)-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25		 23			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20695&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831937	49688769					C03834	ZINC14974341	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37445	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)Cc1ccccc1)-c1ccc(F)cc1	InChI=1S/C28H34FN3O5/c1-18(2)26-24(14-13-22(33)15-23(34)16-25(35)36)32(21-11-9-20(29)10-12-21)30-27(26)28(37)31(3)17-19-7-5-4-6-8-19/h4-12,18,22-23,33-34H,13-17H2,1-3H3,(H,35,36)/p-1/t22-,23-/m1/s1	NKXSDKKNJJYOFA-DHIUTWEWSA-M	20696	Tertiary Amide Analog, 39::sodium (3R,5R)-7-{3-[benzyl(methyl)carbamoyl]-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl}-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5.9		 0.2			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20696&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59832008	49688770					C03834	ZINC14968003	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37446	CCN(Cc1ccccc1)C(=O)c1nn(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1C(C)C)-c1ccc(F)cc1	InChI=1S/C29H36FN3O5/c1-4-32(18-20-8-6-5-7-9-20)29(38)28-27(19(2)3)25(15-14-23(34)16-24(35)17-26(36)37)33(31-28)22-12-10-21(30)11-13-22/h5-13,19,23-24,34-35H,4,14-18H2,1-3H3,(H,36,37)/p-1/t23-,24-/m1/s1	OTMXXXNXTHWXTC-DNQXCXABSA-M	20697	Tertiary Amide Analog, 40::sodium (3R,5R)-7-{3-[benzyl(ethyl)carbamoyl]-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl}-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.8		 5.5			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20697&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831927	49688771					C03834	ZINC14974344	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37447	CC(C)N(Cc1ccccc1)C(=O)c1nn(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1C(C)C)-c1ccc(F)cc1	InChI=1S/C30H38FN3O5/c1-19(2)28-26(15-14-24(35)16-25(36)17-27(37)38)34(23-12-10-22(31)11-13-23)32-29(28)30(39)33(20(3)4)18-21-8-6-5-7-9-21/h5-13,19-20,24-25,35-36H,14-18H2,1-4H3,(H,37,38)/p-1/t24-,25-/m1/s1	RUTQTRSUIHEZES-JWQCQUIFSA-M	20698	Tertiary Amide Analog, 41::sodium (3R,5R)-7-{3-[benzyl(propan-2-yl)carbamoyl]-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl}-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9.8		 10			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20698&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831948	49688772					C03834	ZINC14974347	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37448	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)Cc1ccccc1C)-c1ccc(F)cc1	InChI=1S/C29H36FN3O5/c1-18(2)27-25(14-13-23(34)15-24(35)16-26(36)37)33(22-11-9-21(30)10-12-22)31-28(27)29(38)32(4)17-20-8-6-5-7-19(20)3/h5-12,18,23-24,34-35H,13-17H2,1-4H3,(H,36,37)/p-1/t23-,24-/m1/s1	MPCLUTMSVJUDGE-DNQXCXABSA-M	20699	Tertiary Amide Analog, 32::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{methyl[(2-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 16		 2.1			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20699&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59832009	49688773					C03834	ZINC14974350	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37449	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)Cc1cccc(C)c1)-c1ccc(F)cc1	InChI=1S/C29H36FN3O5/c1-18(2)27-25(13-12-23(34)15-24(35)16-26(36)37)33(22-10-8-21(30)9-11-22)31-28(27)29(38)32(4)17-20-7-5-6-19(3)14-20/h5-11,14,18,23-24,34-35H,12-13,15-17H2,1-4H3,(H,36,37)/p-1/t23-,24-/m1/s1	GIAAXDOFERLIMT-DNQXCXABSA-M	20700	Tertiary Amide Analog, 42::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{methyl[(3-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.1		 0.6			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20700&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831961	49688774					C03834	ZINC14974353	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37450	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)Cc1ccc(C)cc1)-c1ccc(F)cc1	InChI=1S/C29H36FN3O5/c1-18(2)27-25(14-13-23(34)15-24(35)16-26(36)37)33(22-11-9-21(30)10-12-22)31-28(27)29(38)32(4)17-20-7-5-19(3)6-8-20/h5-12,18,23-24,34-35H,13-17H2,1-4H3,(H,36,37)/p-1/t23-,24-/m1/s1	AALVMKWOJQCVKH-DNQXCXABSA-M	20701	Tertiary Amide Analog, 43::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{methyl[(4-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9.9		 1.8			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20701&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831964	49688775					C03834	ZINC14974356	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37451	COc1ccc(CN(C)C(=O)c2nn(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C(C)C)-c2ccc(F)cc2)cc1	InChI=1S/C29H36FN3O6/c1-18(2)27-25(14-11-22(34)15-23(35)16-26(36)37)33(21-9-7-20(30)8-10-21)31-28(27)29(38)32(3)17-19-5-12-24(39-4)13-6-19/h5-10,12-13,18,22-23,34-35H,11,14-17H2,1-4H3,(H,36,37)/p-1/t22-,23-/m1/s1	AEYTZQNRVNCKDQ-DHIUTWEWSA-M	20702	Tertiary Amide Analog, 44::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-methoxyphenyl)methyl](methyl)carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12		 0.3			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20702&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831965	49688776					C03834	ZINC14974360	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37452	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)Cc1ccccc1F)-c1ccc(F)cc1	InChI=1S/C28H33F2N3O5/c1-17(2)26-24(13-12-21(34)14-22(35)15-25(36)37)33(20-10-8-19(29)9-11-20)31-27(26)28(38)32(3)16-18-6-4-5-7-23(18)30/h4-11,17,21-22,34-35H,12-16H2,1-3H3,(H,36,37)/p-1/t21-,22-/m1/s1	CWNFWNFUXTYABU-FGZHOGPDSA-M	20703	Tertiary Amide Analog, 45::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(2-fluorophenyl)methyl](methyl)carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.8		 0.5			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20703&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831966	49688777					C03834	ZINC14974363	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37453	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)Cc1cccc(F)c1)-c1ccc(F)cc1	InChI=1S/C28H33F2N3O5/c1-17(2)26-24(12-11-22(34)14-23(35)15-25(36)37)33(21-9-7-19(29)8-10-21)31-27(26)28(38)32(3)16-18-5-4-6-20(30)13-18/h4-10,13,17,22-23,34-35H,11-12,14-16H2,1-3H3,(H,36,37)/p-1/t22-,23-/m1/s1	OQAJLGZZINRLJK-DHIUTWEWSA-M	20704	Tertiary Amide Analog, 46::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(3-fluorophenyl)methyl](methyl)carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.9		 0.2			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20704&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59832060	49688778					C03834	ZINC14968012	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37454	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)Cc1ccc(F)cc1)-c1ccc(F)cc1	InChI=1S/C28H33F2N3O5/c1-17(2)26-24(13-12-22(34)14-23(35)15-25(36)37)33(21-10-8-20(30)9-11-21)31-27(26)28(38)32(3)16-18-4-6-19(29)7-5-18/h4-11,17,22-23,34-35H,12-16H2,1-3H3,(H,36,37)/p-1/t22-,23-/m1/s1	DBVKNXVHMHULLN-DHIUTWEWSA-M	20705	Tertiary Amide Analog, 47::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-fluorophenyl)methyl](methyl)carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.6		 0.5			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20705&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831977	49688779					C03834	ZINC14974365	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37455	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)Cc1ccc(F)cc1F)-c1ccc(F)cc1	InChI=1S/C28H32F3N3O5/c1-16(2)26-24(11-10-21(35)13-22(36)14-25(37)38)34(20-8-6-18(29)7-9-20)32-27(26)28(39)33(3)15-17-4-5-19(30)12-23(17)31/h4-9,12,16,21-22,35-36H,10-11,13-15H2,1-3H3,(H,37,38)/p-1/t21-,22-/m1/s1	RPWLMFICBLJVLA-FGZHOGPDSA-M	20706	Tertiary Amide Analog, 48::sodium (3R,5R)-7-(3-{[(2,4-difluorophenyl)methyl](methyl)carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.0		 2.1			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20706	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20706&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831987	49688780					C03834	ZINC14974368	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37456	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)Cc1cccc(F)c1F)-c1ccc(F)cc1	InChI=1S/C28H32F3N3O5/c1-16(2)25-23(12-11-20(35)13-21(36)14-24(37)38)34(19-9-7-18(29)8-10-19)32-27(25)28(39)33(3)15-17-5-4-6-22(30)26(17)31/h4-10,16,20-21,35-36H,11-15H2,1-3H3,(H,37,38)/p-1/t20-,21-/m1/s1	ZPCFNXVGMRHCCF-NHCUHLMSSA-M	20707	Tertiary Amide Analog, 49::sodium (3R,5R)-7-(3-{[(2,3-difluorophenyl)methyl](methyl)carbamoyl}-1-(4-fluorophenyl)-4-(propan-2-yl)-1H-pyrazol-5-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9.0		 0.6			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20707&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59832042	49688781					C03834	ZINC14974370	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37457	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)[C@H](C)c1ccccc1)-c1ccc(F)cc1	InChI=1S/C29H36FN3O5/c1-18(2)27-25(15-14-23(34)16-24(35)17-26(36)37)33(22-12-10-21(30)11-13-22)31-28(27)29(38)32(4)19(3)20-8-6-5-7-9-20/h5-13,18-19,23-24,34-35H,14-17H2,1-4H3,(H,36,37)/p-1/t19-,23-,24-/m1/s1	MPDDTAJMJCESGV-CTUHWIOQSA-M	20708	Tertiary Amide Analog, 50::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{methyl[(1R)-1-phenylethyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.5		 0.3			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20708&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44629556	49688782					C03834	ZINC14974373	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37458	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N(C)[C@@H](C)c1ccccc1)-c1ccc(F)cc1	InChI=1S/C29H36FN3O5/c1-18(2)27-25(15-14-23(34)16-24(35)17-26(36)37)33(22-12-10-21(30)11-13-22)31-28(27)29(38)32(4)19(3)20-8-6-5-7-9-20/h5-13,18-19,23-24,34-35H,14-17H2,1-4H3,(H,36,37)/p-1/t19-,23+,24+/m0/s1	MPDDTAJMJCESGV-WUMKDDEVSA-M	20709	Tertiary Amide Analog, 51::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{methyl[(1S)-1-phenylethyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 45		 3.5			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20709&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59832006	49688783					C03834	ZINC14974376	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37459	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N1CCCC1c1ccccc1)-c1ccc(F)cc1	InChI=1S/C30H36FN3O5/c1-19(2)28-26(15-14-23(35)17-24(36)18-27(37)38)34(22-12-10-21(31)11-13-22)32-29(28)30(39)33-16-6-9-25(33)20-7-4-3-5-8-20/h3-5,7-8,10-13,19,23-25,35-36H,6,9,14-18H2,1-2H3,(H,37,38)/p-1/t23-,24-,25?/m1/s1	JDNNJMMIANDJER-AEAWWFNXSA-M	20710	Tertiary Amide Analog, 52::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-[(2-phenylpyrrolidin-1-yl)carbonyl]-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.3		 4.0			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20710&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59831934	49688784					C03834	ZINC14974383	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37460	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N1CCCCC1c1ccccc1)-c1ccc(F)cc1	InChI=1S/C31H38FN3O5/c1-20(2)29-27(16-15-24(36)18-25(37)19-28(38)39)35(23-13-11-22(32)12-14-23)33-30(29)31(40)34-17-7-6-10-26(34)21-8-4-3-5-9-21/h3-5,8-9,11-14,20,24-26,36-37H,6-7,10,15-19H2,1-2H3,(H,38,39)/p-1/t24-,25-,26?/m1/s1	DGPVRQDECQBJDH-YFHSQZFMSA-M	20711	Tertiary Amide Analog, 53::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-[(2-phenylpiperidin-1-yl)carbonyl]-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.1		 1.1			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20711&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59832053	49688785					C03834	ZINC14974388	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37461	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N1CCCC(C1)c1ccccc1)-c1ccc(F)cc1	InChI=1S/C31H38FN3O5/c1-20(2)29-27(15-14-25(36)17-26(37)18-28(38)39)35(24-12-10-23(32)11-13-24)33-30(29)31(40)34-16-6-9-22(19-34)21-7-4-3-5-8-21/h3-5,7-8,10-13,20,22,25-26,36-37H,6,9,14-19H2,1-2H3,(H,38,39)/p-1/t22?,25-,26-/m1/s1	YLAVHPQPEFUCRY-FLZRTACHSA-M	20712	Tertiary Amide Analog, 54::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-[(3-phenylpiperidin-1-yl)carbonyl]-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.5		 0.4			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20712&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91895933	49688786					C03834	ZINC14974390	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
37462	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)n(nc1C(=O)N1CCC[C@@H](C1)c1ccccc1)-c1ccc(F)cc1	InChI=1S/C31H38FN3O5/c1-20(2)29-27(15-14-25(36)17-26(37)18-28(38)39)35(24-12-10-23(32)11-13-24)33-30(29)31(40)34-16-6-9-22(19-34)21-7-4-3-5-8-21/h3-5,7-8,10-13,20,22,25-26,36-37H,6,9,14-19H2,1-2H3,(H,38,39)/p-1/t22-,25+,26+/m0/s1	YLAVHPQPEFUCRY-HDYLNDSGSA-M	20713	Tertiary Amide Analog, 55::sodium (3R,5R)-7-[1-(4-fluorophenyl)-3-{[(3R)-3-phenylpiperidin-1-yl]carbonyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.0		 0.3			7.2	37.00 C	Curated from the literature by BindingDB	10.1021/jm070849r	10.7270/Q2VD6WRD	18072721	aid1798004		Pfefferkorn, JA; Choi, C; Larsen, SD; Auerbach, B; Hutchings, R; Park, W; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C; Harris, MS; Pavlovsky, A; Bainbridge, G; Caspers, N; Kowala, M; Tait, BD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20713	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20713&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			59832049	49688787					C03834		1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297715	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)N(C)S(C)(=O)=O	InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/p-1/b10-9+/t16-,17-/m1/s1	BPRHUIZQVSMCRT-VEUZHWNKSA-M	50371228	Crestor::ROSUVASTATIN CALCIUM::Rosuvastatin::US9006282, Rosuvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50371228	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50371228&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			9869776	160850329					C03834	ZINC01535101	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297716	COC1C[C@@H](C[C@H](O1)\C=C\c1c(nc(nc1-c1ccc(F)cc1)N(C)S(C)(=O)=O)C(C)C)OC(=O)c1cccnc1	InChI=1S/C29H33FN4O6S/c1-18(2)26-24(27(19-8-10-21(30)11-9-19)33-29(32-26)34(3)41(5,36)37)13-12-22-15-23(16-25(38-4)39-22)40-28(35)20-7-6-14-31-17-20/h6-14,17-18,22-23,25H,15-16H2,1-5H3/b13-12+/t22-,23-,25?/m1/s1	WBBZMHQYYBMWIC-OETWXICISA-N	155374	US9006282, Example 2, Compound 2::US9102656, Example 2, Compound 1	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		<1					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155374&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46894122	253658312							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297717	CCCOC1C[C@@H](C[C@H](O1)\C=C\c1c(nc(nc1-c1ccc(F)cc1)N(C)S(C)(=O)=O)C(C)C)OC(=O)c1cccnc1	InChI=1S/C31H37FN4O6S/c1-6-16-40-27-18-25(42-30(37)22-8-7-15-33-19-22)17-24(41-27)13-14-26-28(20(2)3)34-31(36(4)43(5,38)39)35-29(26)21-9-11-23(32)12-10-21/h7-15,19-20,24-25,27H,6,16-18H2,1-5H3/b14-13+/t24-,25-,27?/m1/s1	OFSINOWHTJMWNB-DQLLTYADSA-N	155375	US9006282, Example 2, Compound 3::US9102656, Example 2, Compound 2	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155375&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46932557	253658313							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297718	CC(C)OC1C[C@@H](C[C@H](O1)\C=C\c1c(nc(nc1-c1ccc(F)cc1)N(C)S(C)(=O)=O)C(C)C)OCc1ccccc1	InChI=1S/C32H40FN3O5S/c1-21(2)30-28(31(24-12-14-25(33)15-13-24)35-32(34-30)36(5)42(6,37)38)17-16-26-18-27(19-29(41-26)40-22(3)4)39-20-23-10-8-7-9-11-23/h7-17,21-22,26-27,29H,18-20H2,1-6H3/b17-16+/t26-,27-,29?/m1/s1	HPMKWIWLIPTFQV-FJAMEXCJSA-N	155376	US9006282, Example 2, Compound 4::US9102656, Example 2, Compound 3	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155376&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46928592	253658314							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297719	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@H](CC(OC(C)(C)C)O1)OCc1ccccc1)N(C)S(C)(=O)=O	InChI=1S/C33H42FN3O5S/c1-22(2)30-28(31(24-13-15-25(34)16-14-24)36-32(35-30)37(6)43(7,38)39)18-17-26-19-27(20-29(41-26)42-33(3,4)5)40-21-23-11-9-8-10-12-23/h8-18,22,26-27,29H,19-21H2,1-7H3/b18-17+/t26-,27-,29?/m1/s1	COCIHEXJGZOSOJ-MXUUAITNSA-N	155377	US9006282, Example 2, Compound 5::US9102656, Example 2, Compound 5	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155377&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46932648	253658315							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297720	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@H](CC(OCC=C)O1)OCc1ccccc1)N(C)S(C)(=O)=O	InChI=1S/C32H38FN3O5S/c1-6-18-39-29-20-27(40-21-23-10-8-7-9-11-23)19-26(41-29)16-17-28-30(22(2)3)34-32(36(4)42(5,37)38)35-31(28)24-12-14-25(33)15-13-24/h6-17,22,26-27,29H,1,18-21H2,2-5H3/b17-16+/t26-,27-,29?/m1/s1	OMFUKTXBDFLJRM-FJAMEXCJSA-N	155378	US9006282, Example 2, Compound 6::US9102656, Example 2, Compound 6	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155378&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46932647	253658316							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297721	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@H](CC(OCC(Cl)(Cl)Cl)O1)OCc1ccccc1)N(C)S(C)(=O)=O	InChI=1S/C31H35Cl3FN3O5S/c1-20(2)28-26(29(22-10-12-23(35)13-11-22)37-30(36-28)38(3)44(4,39)40)15-14-24-16-25(41-18-21-8-6-5-7-9-21)17-27(43-24)42-19-31(32,33)34/h5-15,20,24-25,27H,16-19H2,1-4H3/b15-14+/t24-,25-,27?/m1/s1	HFUHFPLGHKFQPB-HQBUWMEKSA-N	155379	US9006282, Example 2, Compound 7::US9102656, Example 2, Compound 7	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155379&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46928486	253658317							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297722	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(Oc2c(F)cc(F)cc2F)O1)N(C)S(C)(=O)=O	InChI=1S/C28H29F4N3O5S/c1-15(2)25-21(26(16-5-7-17(29)8-6-16)34-28(33-25)35(3)41(4,37)38)10-9-20-13-19(36)14-24(39-20)40-27-22(31)11-18(30)12-23(27)32/h5-12,15,19-20,24,36H,13-14H2,1-4H3/b10-9+/t19-,20-,24?/m1/s1	MAPWRPSCIIWUDB-HHFGZVMTSA-N	155380	US9006282, Example 2, Compound 8::US9102656, Example 2, Compound 8	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155380&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46928590	253658318							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297723	COc1ccc(OC2C[C@H](O)C[C@H](O2)\C=C\c2c(nc(nc2-c2ccc(F)cc2)N(C)S(C)(=O)=O)C(C)C)c(OC)c1	InChI=1S/C30H36FN3O7S/c1-18(2)28-24(29(19-7-9-20(31)10-8-19)33-30(32-28)34(3)42(6,36)37)13-11-23-15-21(35)16-27(40-23)41-25-14-12-22(38-4)17-26(25)39-5/h7-14,17-18,21,23,27,35H,15-16H2,1-6H3/b13-11+/t21-,23-,27?/m1/s1	CQYSSVVEFOVLEM-PCMIMOEYSA-N	155381	US9006282, Example 2, Compound 9::US9102656, Example 2, Compound 9	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155381&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46928591	253658319							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297724	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(OCC(Cl)(Cl)Cl)O1)N(C)S(C)(=O)=O	InChI=1S/C24H29Cl3FN3O5S/c1-14(2)21-19(10-9-18-11-17(32)12-20(36-18)35-13-24(25,26)27)22(15-5-7-16(28)8-6-15)30-23(29-21)31(3)37(4,33)34/h5-10,14,17-18,20,32H,11-13H2,1-4H3/b10-9+/t17-,18-,20?/m1/s1	XHZRVKRXKZCVLL-JKHXERJMSA-N	155382	US9006282, Example 2, Compound 10::US9102656, Example 2, Compound 10	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155382&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46928487	253658320							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297725	CCCOC1C[C@H](O)C[C@H](O1)\C=C\c1c(nc(nc1-c1ccc(F)cc1)N(C)S(C)(=O)=O)C(C)C	InChI=1S/C25H34FN3O5S/c1-6-13-33-22-15-19(30)14-20(34-22)11-12-21-23(16(2)3)27-25(29(4)35(5,31)32)28-24(21)17-7-9-18(26)10-8-17/h7-12,16,19-20,22,30H,6,13-15H2,1-5H3/b12-11+/t19-,20-,22?/m1/s1	UCTBEFNFYMBJKW-KKZBYLJVSA-N	155383	US9006282, Example 2, Compound 11::US9102656, Example 2, Compound 11	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155383&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46928593	253658321							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297726	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/p-1/t26-,27-/m1/s1	XUKUURHRXDUEBC-KAYWLYCHSA-M	50221993	CHEMBL393220::Calcium (betaR,deltaR)-2-(p-fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate (1:2)::US9006282, Atorvastatin::atorvastatin calcium::calcium bis{(3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate}	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221993&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			17589822	104094498	50686	CHEMBL393220			C06834	ZINC03920719	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297727	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C33H33FN2O4/c1-21(2)31-30(33(39)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-27-19-26(37)20-28(38)40-27/h3-16,21,26-27,37H,17-20H2,1-2H3,(H,35,39)/t26-,27-/m1/s1	OUCSEDFVYPBLLF-KAYWLYCHSA-N	50011032	5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide::Atorvastatin lactone::CHEMBL333687::US9006282, Example 3, Compound 2	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011032	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011032&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6483036	103923727		CHEMBL333687		2957		ZINC03920720	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297728	COC1C[C@@H](C[C@@H](CCn2c(C(C)C)c(C(=O)Nc3ccccc3)c(c2-c2ccc(F)cc2)-c2ccccc2)O1)OC(=O)c1cccnc1	InChI=1S/C40H40FN3O5/c1-26(2)37-36(39(45)43-31-14-8-5-9-15-31)35(27-11-6-4-7-12-27)38(28-16-18-30(41)19-17-28)44(37)22-20-32-23-33(24-34(47-3)48-32)49-40(46)29-13-10-21-42-25-29/h4-19,21,25-26,32-34H,20,22-24H2,1-3H3,(H,43,45)/t32-,33-,34?/m1/s1	ZFYLYTBCONNVCQ-DOTKWZJKSA-N	155384	US9006282, Example 3, Compound 3	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		<1					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155384&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46893544	253658322							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297729	CCCOC1C[C@H](O)C[C@@H](CCn2c(C(C)C)c(C(=O)Nc3ccccc3)c(c2-c2ccc(F)cc2)-c2ccccc2)O1	InChI=1S/C36H41FN2O4/c1-4-21-42-31-23-29(40)22-30(43-31)19-20-39-34(24(2)3)33(36(41)38-28-13-9-6-10-14-28)32(25-11-7-5-8-12-25)35(39)26-15-17-27(37)18-16-26/h5-18,24,29-31,40H,4,19-23H2,1-3H3,(H,38,41)/t29-,30-,31?/m1/s1	QSPZJDGFFMSQPC-KCUXUGRMSA-N	155385	US9006282, Example 3, Compound 4	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		<1					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155385&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46917282	253658323							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297730	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(OC2CCCCC2)O1)-c1ccccc1	InChI=1S/C39H45FN2O4/c1-26(2)37-36(39(44)41-30-14-8-4-9-15-30)35(27-12-6-3-7-13-27)38(28-18-20-29(40)21-19-28)42(37)23-22-33-24-31(43)25-34(46-33)45-32-16-10-5-11-17-32/h3-4,6-9,12-15,18-21,26,31-34,43H,5,10-11,16-17,22-25H2,1-2H3,(H,41,44)/t31-,33-,34?/m1/s1	YFXXPBMCYVXPEQ-FIDRQUTQSA-N	155386	US9006282, Example 3, Compound 5	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		<1					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155386&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46917350	253658324							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297731	CC(C)OC1C[C@@H](C[C@@H](CCn2c(C(C)C)c(C(=O)Nc3ccccc3)c(c2-c2ccc(F)cc2)-c2ccccc2)O1)OCc1ccccc1	InChI=1S/C43H47FN2O4/c1-29(2)41-40(43(47)45-35-18-12-7-13-19-35)39(32-16-10-6-11-17-32)42(33-20-22-34(44)23-21-33)46(41)25-24-36-26-37(27-38(50-36)49-30(3)4)48-28-31-14-8-5-9-15-31/h5-23,29-30,36-38H,24-28H2,1-4H3,(H,45,47)/t36-,37-,38?/m1/s1	NWLKHHPNBMCPNS-QCUZFKLTSA-N	155387	US9006282, Example 3, Compound 6	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155387&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46917351	253658325							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297732	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@H](CC(OC(C)(C)C)O1)OCc1ccccc1)-c1ccccc1	InChI=1S/C44H49FN2O4/c1-30(2)41-40(43(48)46-35-19-13-8-14-20-35)39(32-17-11-7-12-18-32)42(33-21-23-34(45)24-22-33)47(41)26-25-36-27-37(28-38(50-36)51-44(3,4)5)49-29-31-15-9-6-10-16-31/h6-24,30,36-38H,25-29H2,1-5H3,(H,46,48)/t36-,37-,38?/m1/s1	IIVXJOHFZYFNLK-QCUZFKLTSA-N	155388	US9006282, Example 3, Compound 7	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155388&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46917352	253658326							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297733	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@H](CC(OCC=C)O1)OCc1ccccc1)-c1ccccc1	InChI=1S/C43H45FN2O4/c1-4-26-48-38-28-37(49-29-31-14-8-5-9-15-31)27-36(50-38)24-25-46-41(30(2)3)40(43(47)45-35-18-12-7-13-19-35)39(32-16-10-6-11-17-32)42(46)33-20-22-34(44)23-21-33/h4-23,30,36-38H,1,24-29H2,2-3H3,(H,45,47)/t36-,37-,38?/m1/s1	RFBDJMVSIWLFFC-QCUZFKLTSA-N	155389	US9006282, Example 3, Compound 8	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155389&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46917353	253658327							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
297734	COc1ccc(OC2C[C@H](O)C[C@@H](CCn3c(C(C)C)c(C(=O)Nc4ccccc4)c(c3-c3ccc(F)cc3)-c3ccccc3)O2)c(OC)c1	InChI=1S/C41H43FN2O6/c1-26(2)39-38(41(46)43-30-13-9-6-10-14-30)37(27-11-7-5-8-12-27)40(28-15-17-29(42)18-16-28)44(39)22-21-33-23-31(45)24-36(49-33)50-34-20-19-32(47-3)25-35(34)48-4/h5-20,25-26,31,33,36,45H,21-24H2,1-4H3,(H,43,46)/t31-,33-,36?/m1/s1	GOANSGMMXGHJHV-FOQVLGDDSA-N	155390	US9006282, Example 3, Compound 9	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		<1					7.2		US Patent		10.7270/Q28K77T8		aid1801185	US9006282	Lindsay, D; Jackson, P; Hindley, S; Bhamra, I	RedX Pharma Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=155390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=155390&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			46917421	253658328							1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014071	C[C@@H]1C[C@H](OC(=O)CC=C)[C@@H]2[C@@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C23H32O5/c1-4-5-21(25)28-20-11-14(2)10-16-7-6-15(3)19(23(16)20)9-8-18-12-17(24)13-22(26)27-18/h4,6-7,10,14-15,17-20,23-24H,1,5,8-9,11-13H2,2-3H3/t14-,15-,17+,18?,19-,20-,23-/m0/s1	IKPMDELXWPIPQR-GXPTYBKBSA-N	50009407	But-3-enoic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL311800	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.9							ChEMBL	10.1021/jm00112a024	10.7270/Q29S1Q0D	1875344			Lee, TJ; Holtz, WJ; Smith, RL; Alberts, AW; Gilfillan, JL	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009407&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44461475	103922419		CHEMBL311800				ZINC26492230	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014072	C[C@@H]1C[C@H](OC(C)=O)[C@@H]2[C@@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C21H30O5/c1-12-8-15-5-4-13(2)18(21(15)19(9-12)25-14(3)22)7-6-17-10-16(23)11-20(24)26-17/h4-5,8,12-13,16-19,21,23H,6-7,9-11H2,1-3H3/t12-,13-,16+,17?,18-,19-,21-/m0/s1	ASSFTGNZZQBCNK-FPKFEHKASA-N	50009408	Acetic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL310601	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 269							ChEMBL	10.1021/jm00112a024	10.7270/Q29S1Q0D	1875344			Lee, TJ; Holtz, WJ; Smith, RL; Alberts, AW; Gilfillan, JL	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009408&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44461289	103922420		CHEMBL310601				ZINC26495664	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014073	C[C@@H]1C[C@H](OCc2ccc(Cl)cc2)[C@@H]2[C@@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C26H33ClO4/c1-16-11-19-6-3-17(2)23(10-9-22-13-21(28)14-25(29)31-22)26(19)24(12-16)30-15-18-4-7-20(27)8-5-18/h3-8,11,16-17,21-24,26,28H,9-10,12-15H2,1-2H3/t16-,17-,21+,22?,23-,24-,26-/m0/s1	ADZPEGVGCRMCJB-HFFWVFNMSA-N	50009409	6-{2-[8-(4-Chloro-benzyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL309410	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 170							ChEMBL	10.1021/jm00112a024	10.7270/Q29S1Q0D	1875344			Lee, TJ; Holtz, WJ; Smith, RL; Alberts, AW; Gilfillan, JL	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009409&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44461515	103922421		CHEMBL309410				ZINC26494983	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014074	C[C@@H]1C[C@H](OCC=C)[C@@H]2[C@@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C22H32O4/c1-4-9-25-20-11-14(2)10-16-6-5-15(3)19(22(16)20)8-7-18-12-17(23)13-21(24)26-18/h4-6,10,14-15,17-20,22-23H,1,7-9,11-13H2,2-3H3/t14-,15-,17+,18?,19-,20-,22-/m0/s1	LUWATWUCYPDVDW-BTRBWJCUSA-N	50009410	6-[2-(8-Allyloxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL310877	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 370							ChEMBL	10.1021/jm00112a024	10.7270/Q29S1Q0D	1875344			Lee, TJ; Holtz, WJ; Smith, RL; Alberts, AW; Gilfillan, JL	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009410&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44461516	103922422		CHEMBL310877				ZINC26494988	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014075	C[C@@H]1C[C@H](OCc2ccc(F)cc2)[C@@H]2[C@@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C26H33FO4/c1-16-11-19-6-3-17(2)23(10-9-22-13-21(28)14-25(29)31-22)26(19)24(12-16)30-15-18-4-7-20(27)8-5-18/h3-8,11,16-17,21-24,26,28H,9-10,12-15H2,1-2H3/t16-,17-,21+,22?,23-,24-,26-/m0/s1	BJHHGFRLJBTPMS-HFFWVFNMSA-N	50009411	6-{2-[8-(4-Fluoro-benzyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL312626	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.7							ChEMBL	10.1021/jm00112a024	10.7270/Q29S1Q0D	1875344			Lee, TJ; Holtz, WJ; Smith, RL; Alberts, AW; Gilfillan, JL	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009411&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44461474	103922423		CHEMBL312626				ZINC26491775	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014076	CO[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C20H30O4/c1-12-8-14-5-4-13(2)17(20(14)18(9-12)23-3)7-6-16-10-15(21)11-19(22)24-16/h4-5,8,12-13,15-18,20-21H,6-7,9-11H2,1-3H3/t12-,13-,15+,16?,17-,18-,20-/m0/s1	XKQNSUWUMIUMLV-OWOJFGMGSA-N	50009412	4-Hydroxy-6-[2-(8-methoxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL81138	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2810							ChEMBL	10.1021/jm00112a024	10.7270/Q29S1Q0D	1875344			Lee, TJ; Holtz, WJ; Smith, RL; Alberts, AW; Gilfillan, JL	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009412&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44461272	103922424		CHEMBL81138				ZINC26497377	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014077	C[C@@H]1C[C@H](OC(=O)Cc2ccccc2)[C@@H]2[C@@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C27H34O5/c1-17-12-20-9-8-18(2)23(11-10-22-15-21(28)16-26(30)31-22)27(20)24(13-17)32-25(29)14-19-6-4-3-5-7-19/h3-9,12,17-18,21-24,27-28H,10-11,13-16H2,1-2H3/t17-,18-,21+,22+,23-,24-,27-/m0/s1	QXEJOEBXRQAVIM-KQGSDPMOSA-N	50009413	CHEMBL3085466::Phenyl-acetic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 19							ChEMBL	10.1021/jm00112a024	10.7270/Q29S1Q0D	1875344			Lee, TJ; Holtz, WJ; Smith, RL; Alberts, AW; Gilfillan, JL	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009413&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			12953878	103922425		CHEMBL3085466				ZINC26495661	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014078	C[C@@H]1C[C@H](OCc2ccccc2)[C@@H]2[C@@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C26H34O4/c1-17-12-20-9-8-18(2)23(11-10-22-14-21(27)15-25(28)30-22)26(20)24(13-17)29-16-19-6-4-3-5-7-19/h3-9,12,17-18,21-24,26-27H,10-11,13-16H2,1-2H3/t17-,18-,21+,22?,23-,24-,26-/m0/s1	IGWJXDKXBWRVCJ-AHGFMRBSSA-N	50009414	6-[2-(8-Benzyloxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL311047	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 27							ChEMBL	10.1021/jm00112a024	10.7270/Q29S1Q0D	1875344			Lee, TJ; Holtz, WJ; Smith, RL; Alberts, AW; Gilfillan, JL	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009414&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44461273	103922426		CHEMBL311047				ZINC26497715	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014079	C[C@@H]1C[C@H](OCC(C)=C)[C@@H]2[C@@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C23H34O4/c1-14(2)13-26-21-10-15(3)9-17-6-5-16(4)20(23(17)21)8-7-19-11-18(24)12-22(25)27-19/h5-6,9,15-16,18-21,23-24H,1,7-8,10-13H2,2-4H3/t15-,16-,18+,19?,20-,21-,23-/m0/s1	NHTHXZVTVJEHNY-IIIOEECLSA-N	50009415	6-{2-[2,6-Dimethyl-8-(2-methyl-allyloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL81519	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 360							ChEMBL	10.1021/jm00112a024	10.7270/Q29S1Q0D	1875344			Lee, TJ; Holtz, WJ; Smith, RL; Alberts, AW; Gilfillan, JL	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009415&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44461517	103922427		CHEMBL81519				ZINC26494992	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014082	CCC(C)(C)C(=O)O[C@H]1C[C@H](C)[C@@H](O)[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C25H42O6/c1-6-25(4,5)24(29)31-20-11-15(3)23(28)19-9-7-14(2)18(22(19)20)10-8-17-12-16(26)13-21(27)30-17/h14-20,22-23,26,28H,6-13H2,1-5H3/t14-,15+,16+,17?,18-,19+,20-,22?,23+/m0/s1	SOAAQDRMUAREJG-OAIORBKXSA-N	50009417	2,2-Dimethyl-butyric acid 4-hydroxy-8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-decahydro-naphthalen-1-yl ester::CHEMBL3349546	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 49							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009417&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718432	103922429		CHEMBL3349546CHEMBL431604				ZINC26502492	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014083	CCC(C)(C)C(=O)O[C@H]1CC(C)(C)O[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C25H42O6/c1-7-24(3,4)23(28)30-20-14-25(5,6)31-19-11-8-15(2)18(22(19)20)10-9-17-12-16(26)13-21(27)29-17/h15-20,22,26H,7-14H2,1-6H3/t15-,16+,17?,18-,19+,20-,22?/m0/s1	SCTOXHHZCUZJNZ-ZPIQVHHISA-N	50009418	2,2-Dimethyl-butyric acid 5-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2,2,6-trimethyl-octahydro-chromen-4-yl ester::CHEMBL3349535	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 35							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009418&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718422	103922430		CHEMBL3349535CHEMBL83483				ZINC26502484	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014085	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)[C@@H](O)[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C25H42O6/c1-6-25(4,5)24(29)31-20-11-15(3)23(28)19-9-7-14(2)18(22(19)20)10-8-17-12-16(26)13-21(27)30-17/h14-20,22-23,26,28H,6-13H2,1-5H3/t14-,15-,16+,17?,18-,19+,20-,22?,23+/m0/s1	SOAAQDRMUAREJG-RPBQSKQISA-N	50009419	2,2-Dimethyl-butyric acid 4-hydroxy-8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-decahydro-naphthalen-1-yl ester::CHEMBL3349536	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 41							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009419&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718423	103922431		CHEMBL3349536CHEMBL421717				ZINC26500921	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014086	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)[C@@H](OC(=O)N(Cc2ccccc2)Cc2ccccc2)[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C40H55NO7/c1-6-40(4,5)38(44)47-34-21-27(3)37(33-19-17-26(2)32(36(33)34)20-18-31-22-30(42)23-35(43)46-31)48-39(45)41(24-28-13-9-7-10-14-28)25-29-15-11-8-12-16-29/h7-16,26-27,30-34,36-37,42H,6,17-25H2,1-5H3/t26-,27+,30+,31?,32-,33+,34-,36?,37+/m0/s1	KDQFSEFEJYDHTG-MJAAVMQXSA-N	50009422	2,2-Dimethyl-butyric acid 4-dibenzylcarbamoyloxy-8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-decahydro-naphthalen-1-yl ester::CHEMBL3349539	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 16							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009422&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718426	103922434		CHEMBL3349539CHEMBL81430				ZINC26501988	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014087	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)[C@@H](OCCc2ccccc2)[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C33H50O6/c1-6-33(4,5)32(36)39-28-18-22(3)31(37-17-16-23-10-8-7-9-11-23)27-14-12-21(2)26(30(27)28)15-13-25-19-24(34)20-29(35)38-25/h7-11,21-22,24-28,30-31,34H,6,12-20H2,1-5H3/t21-,22+,24+,25?,26-,27+,28-,30?,31+/m0/s1	WNVWCYXHKNNART-BHMJBRCNSA-N	50009423	2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-4-phenethyloxy-decahydro-naphthalen-1-yl ester::CHEMBL3349542	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009423&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718429	103922435		CHEMBL3349542CHEMBL313129				ZINC26502239	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014088	CCC(C)(C)C(=O)O[C@@H](CC(C)=C)C1[C@H](O)CC[C@H](C)[C@@H]1CC[C@@H]1C[C@H](CC(=O)O1)O[Si](C)(C)C(C)(C)C	InChI=1S/C31H56O6Si/c1-12-31(8,9)29(34)36-26(17-20(2)3)28-24(21(4)13-16-25(28)32)15-14-22-18-23(19-27(33)35-22)37-38(10,11)30(5,6)7/h21-26,28,32H,2,12-19H2,1,3-11H3/t21-,22?,23+,24-,25+,26-,28?/m0/s1	AMEKTZOFUFOJDQ-POFCPJKDSA-N	50009421	2,2-Dimethyl-butyric acid 1-(2-{2-[4-(tert-butyl-dimethyl-silanyloxy)-6-oxo-tetrahydro-pyran-2-yl]-ethyl}-6-hydroxy-3-methyl-cyclohexyl)-3-methyl-but-3-enyl ester::CHEMBL3349540	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1700							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009421&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718427	103922433		CHEMBL3349540CHEMBL82160					1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014089	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)CC2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C25H42O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h15-21,23,26H,6-14H2,1-5H3/t15-,16-,17?,18+,19?,20-,21-,23?/m0/s1	RCXGNJNDQYAWDC-IRCAVXPMSA-N	50009420	2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-decahydro-naphthalen-1-yl ester::CHEMBL3349543	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009420&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718430	103922432		CHEMBL3349543CHEMBL85673				ZINC36242993	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014090	CCC(C)(C)C(=O)O[C@H]1C[C@H](C)[C@H](O)[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C25H42O6/c1-6-25(4,5)24(29)31-20-11-15(3)23(28)19-9-7-14(2)18(22(19)20)10-8-17-12-16(26)13-21(27)30-17/h14-20,22-23,26,28H,6-13H2,1-5H3/t14-,15-,16+,17?,18-,19+,20-,22?,23-/m0/s1	SOAAQDRMUAREJG-KOFLVRCSSA-N	50009424	2,2-Dimethyl-butyric acid 4-hydroxy-8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-decahydro-naphthalen-1-yl ester::CHEMBL3349534	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 289							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009424&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718421	103922436		CHEMBL3349534CHEMBL84524				ZINC26502702	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014091	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C(=O)[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C25H40O6/c1-6-25(4,5)24(29)31-20-11-15(3)23(28)19-9-7-14(2)18(22(19)20)10-8-17-12-16(26)13-21(27)30-17/h14-20,22,26H,6-13H2,1-5H3/t14-,15-,16+,17?,18-,19+,20-,22?/m0/s1	CZHGSNWZXTVGFC-NPFFVRAUSA-N	50009425	2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-4-oxo-decahydro-naphthalen-1-yl ester::CHEMBL3349547	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 34							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009425&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718433	103922437		CHEMBL3349547CHEMBL84006				ZINC26502694	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014092	CCC(C)(C)C(=O)O[C@H]1C[C@H](C)C(=O)[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C25H40O6/c1-6-25(4,5)24(29)31-20-11-15(3)23(28)19-9-7-14(2)18(22(19)20)10-8-17-12-16(26)13-21(27)30-17/h14-20,22,26H,6-13H2,1-5H3/t14-,15+,16+,17?,18-,19+,20-,22?/m0/s1	CZHGSNWZXTVGFC-CARFRKRISA-N	50009427	2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-4-oxo-decahydro-naphthalen-1-yl ester::CHEMBL3349533	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 59							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009427&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718420	103922439		CHEMBL3349533CHEMBL84252				ZINC26501214	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014093	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)[C@@H](OC(=O)NCc2ccccc2)[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C33H49NO7/c1-6-33(4,5)31(37)40-27-16-21(3)30(41-32(38)34-19-22-10-8-7-9-11-22)26-14-12-20(2)25(29(26)27)15-13-24-17-23(35)18-28(36)39-24/h7-11,20-21,23-27,29-30,35H,6,12-19H2,1-5H3,(H,34,38)/t20-,21+,23+,24?,25-,26+,27-,29?,30+/m0/s1	ZUURLVDIZFDZJT-UQLLKHDVSA-N	50009426	2,2-Dimethyl-butyric acid 4-benzylcarbamoyloxy-8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-decahydro-naphthalen-1-yl ester::CHEMBL3349538	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009426&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718425	103922438		CHEMBL3349538CHEMBL310463		3028		ZINC26504413	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014094	CCC(C)(C)C(=O)O[C@@H](C[C@@H](C)CO)C1[C@H](O)CC[C@H](C)[C@@H]1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H44O7/c1-6-25(4,5)24(30)32-21(11-15(2)14-26)23-19(16(3)7-10-20(23)28)9-8-18-12-17(27)13-22(29)31-18/h15-21,23,26-28H,6-14H2,1-5H3/t15-,16+,17-,18?,19+,20-,21+,23?/m1/s1	BBJHGQSAVYWHGJ-XPAGCXAMSA-N	50009428	2,2-Dimethyl-butyric acid 4-hydroxy-1-{6-hydroxy-2-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3-methyl-cyclohexyl}-3-methyl-butyl ester::CHEMBL3349537	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2800							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009428&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718424	103922440		CHEMBL3349537CHEMBL310211				ZINC26502765	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014095	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)[C@@H](OP(=O)(c2ccccc2)c2ccccc2)[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C37H51O7P/c1-6-37(4,5)36(40)43-32-21-25(3)35(44-45(41,28-13-9-7-10-14-28)29-15-11-8-12-16-29)31-19-17-24(2)30(34(31)32)20-18-27-22-26(38)23-33(39)42-27/h7-16,24-27,30-32,34-35,38H,6,17-23H2,1-5H3/t24-,25+,26+,27?,30-,31+,32-,34?,35+/m0/s1	OWEDJIZMZBDWGA-DKXMIXIMSA-N	50009429	2,2-Dimethyl-butyric acid 4-(diphenyl-phosphinoyloxy)-8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-decahydro-naphthalen-1-yl ester::CHEMBL3349541	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009429	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009429&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718428	103922441		CHEMBL3349541CHEMBL312594				ZINC49672554	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016466	CCOC(=O)c1c(C(C)C)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c(c1-c1ccc(cc1)C#N)-c1ccc(F)cc1	InChI=1S/C30H31FN2O5/c1-4-37-30(36)27-26(20-7-5-19(17-32)6-8-20)29(21-9-11-22(31)12-10-21)33(28(27)18(2)3)14-13-24-15-23(34)16-25(35)38-24/h5-12,18,23-24,34H,4,13-16H2,1-3H3/t23-,24-/m1/s1	IYDDXEIYERNMIL-DNQXCXABSA-N	50011016	4-(4-Cyano-phenyl)-5-(4-fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL331411	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 280							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011016	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011016&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757160	103923711		CHEMBL331411				ZINC13861024	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016467	CC(C)c1c(Cl)c(Cl)c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H22Cl2FNO3/c1-11(2)19-17(21)18(22)20(12-3-5-13(23)6-4-12)24(19)8-7-15-9-14(25)10-16(26)27-15/h3-6,11,14-15,25H,7-10H2,1-2H3/t14-,15-/m1/s1	SOWQURNDNUWYOW-HUUCEWRRSA-N	50011018	6-{2-[3,4-Dichloro-2-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL332165	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 28							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011018&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785464	103923713		CHEMBL332165				ZINC13861028	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016468	CC(C)c1cc(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccncc1	InChI=1S/C25H27FN2O3/c1-16(2)23-15-22(17-7-10-27-11-8-17)25(18-3-5-19(26)6-4-18)28(23)12-9-21-13-20(29)14-24(30)31-21/h3-8,10-11,15-16,20-21,29H,9,12-14H2,1-2H3/t20-,21-/m1/s1	NTJKXTRCYCPBHT-NHCUHLMSSA-N	50011017	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-3-pyridin-4-yl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL120897	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 310							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011017&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14100427	103923712		CHEMBL120897				ZINC03776727	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016469	CC(C)c1cc(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C26H28FNO3/c1-17(2)24-16-23(18-6-4-3-5-7-18)26(19-8-10-20(27)11-9-19)28(24)13-12-22-14-21(29)15-25(30)31-22/h3-11,16-17,21-22,29H,12-15H2,1-2H3/t21-,22-/m1/s1	QNMWKGJIZRTANI-FGZHOGPDSA-N	50011019	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL333478	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 347							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011019&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757164	103923714		CHEMBL333478				ZINC13861026	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016470	CC(C)c1c(Br)c(Br)c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H22Br2FNO3/c1-11(2)19-17(21)18(22)20(12-3-5-13(23)6-4-12)24(19)8-7-15-9-14(25)10-16(26)27-15/h3-6,11,14-15,25H,7-10H2,1-2H3/t14-,15-/m1/s1	SEESZUWDWXYFGB-HUUCEWRRSA-N	50011020	6-{2-[3,4-Dibromo-2-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL121658	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 28							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011020	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011020&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785466	103923715		CHEMBL121658				ZINC13861029	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016471	CC(C)c1c(cc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C26H28FNO3/c1-17(2)26-23(18-6-4-3-5-7-18)16-24(19-8-10-20(27)11-9-19)28(26)13-12-22-14-21(29)15-25(30)31-22/h3-11,16-17,21-22,29H,12-15H2,1-2H3/t21-,22-/m1/s1	RACCRJRLIWPIFP-FGZHOGPDSA-N	50011021	6-{2-[5-(4-Fluoro-phenyl)-2-isopropyl-3-phenyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL333361	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 120							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011021&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757166	103923716		CHEMBL333361				ZINC13861027	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016472	CCOC(=O)c1c(C(C)C)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c(c1-c1ccccc1)-c1ccccc1	InChI=1S/C29H33NO5/c1-4-34-29(33)26-25(20-11-7-5-8-12-20)28(21-13-9-6-10-14-21)30(27(26)19(2)3)16-15-23-17-22(31)18-24(32)35-23/h5-14,19,22-23,31H,4,15-18H2,1-3H3/t22-,23-/m1/s1	IIJYSCRXMTUPAN-DHIUTWEWSA-N	50011022	1-[2-(4-Hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4,5-diphenyl-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL330777	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 170							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011022	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011022&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757150	103923717		CHEMBL330777				ZINC13861019	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016473	COC(=O)c1c(C(C)C)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c(c1C(=O)OC)-c1ccc(F)cc1	InChI=1S/C24H28FNO7/c1-13(2)21-19(23(29)31-3)20(24(30)32-4)22(14-5-7-15(25)8-6-14)26(21)10-9-17-11-16(27)12-18(28)33-17/h5-8,13,16-17,27H,9-12H2,1-4H3/t16-,17-/m1/s1	UVRRDSHLWNNMFF-IAGOWNOFSA-N	50011023	2-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-5-isopropyl-1H-pyrrole-3,4-dicarboxylic acid dimethyl ester::CHEMBL123357	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 180							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011023	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011023&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785473	103923718		CHEMBL123357				ZINC13861020	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016474	CC(C)c1cc(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccn1	InChI=1S/C25H27FN2O3/c1-16(2)23-15-21(22-5-3-4-11-27-22)25(17-6-8-18(26)9-7-17)28(23)12-10-20-13-19(29)14-24(30)31-20/h3-9,11,15-16,19-20,29H,10,12-14H2,1-2H3/t19-,20-/m1/s1	CYYFWLRWUQEXDC-WOJBJXKFSA-N	50011025	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-3-pyridin-2-yl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL330753	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 46							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011025	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011025&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14100423	103923720		CHEMBL330753				ZINC03777260	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016475	CCOC(=O)c1c(c(C(C)C)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c1-c1ccc(F)cc1)-c1ccccc1	InChI=1S/C29H32FNO5/c1-4-35-29(34)26-25(19-8-6-5-7-9-19)27(18(2)3)31(28(26)20-10-12-21(30)13-11-20)15-14-23-16-22(32)17-24(33)36-23/h5-13,18,22-23,32H,4,14-17H2,1-3H3/t22-,23-/m1/s1	NKFMECVAIOCUQQ-DHIUTWEWSA-N	50011024	2-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-5-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL122219	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 50							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011024	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011024&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757154	103923719		CHEMBL122219				ZINC13861022	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016476	CCOC(=O)c1c(C(C)C)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c(c1C(=O)OCC)-c1ccc(F)cc1	InChI=1S/C26H32FNO7/c1-5-33-25(31)21-22(26(32)34-6-2)24(16-7-9-17(27)10-8-16)28(23(21)15(3)4)12-11-19-13-18(29)14-20(30)35-19/h7-10,15,18-19,29H,5-6,11-14H2,1-4H3/t18-,19-/m1/s1	GKCRROLRCQXGSL-RTBURBONSA-N	50011026	2-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-5-isopropyl-1H-pyrrole-3,4-dicarboxylic acid diethyl ester::CHEMBL123986	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 350							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011026	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011026&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757152	103923721		CHEMBL123986				ZINC13861021	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016477	CCOC(=O)c1c(C(C)C)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c(c1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C29H32FNO5/c1-4-35-29(34)26-25(19-8-6-5-7-9-19)28(20-10-12-21(30)13-11-20)31(27(26)18(2)3)15-14-23-16-22(32)17-24(33)36-23/h5-13,18,22-23,32H,4,14-17H2,1-3H3/t22-,23-/m1/s1	KPINVWVHJUHETP-DHIUTWEWSA-N	50011028	5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL420354	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 200							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011028&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757156	103923723		CHEMBL420354				ZINC13861023	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016478	CCOC(=O)c1c(CC)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c(c1-c1ccccc1)-c1ccccc1	InChI=1S/C28H31NO5/c1-3-23-26(28(32)33-4-2)25(19-11-7-5-8-12-19)27(20-13-9-6-10-14-20)29(23)16-15-22-17-21(30)18-24(31)34-22/h5-14,21-22,30H,3-4,15-18H2,1-2H3/t21-,22-/m1/s1	NSRNYHXNPLWZPI-FGZHOGPDSA-N	50011027	2-Ethyl-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-4,5-diphenyl-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL420337	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 890							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011027&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757148	103923722		CHEMBL420337				ZINC13861018	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016479	CC(C)c1cc(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1cccnc1	InChI=1S/C25H27FN2O3/c1-16(2)23-14-22(18-4-3-10-27-15-18)25(17-5-7-19(26)8-6-17)28(23)11-9-21-12-20(29)13-24(30)31-21/h3-8,10,14-16,20-21,29H,9,11-13H2,1-2H3/t20-,21-/m1/s1	JTECTVWAYXWKMC-NHCUHLMSSA-N	50011029	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-3-pyridin-3-yl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL120949	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 71.0							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011029	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011029&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14100425	103923724		CHEMBL120949				ZINC03777262	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016480	CC(C)c1cc(C(=O)C(F)(F)F)c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H23F4NO4/c1-12(2)18-11-17(21(30)22(24,25)26)20(13-3-5-14(23)6-4-13)27(18)8-7-16-9-15(28)10-19(29)31-16/h3-6,11-12,15-16,28H,7-10H2,1-2H3/t15-,16-/m1/s1	RKUYYDQPUDHAJE-HZPDHXFCSA-N	50011031	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-3-(2,2,2-trifluoro-acetyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL333206	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 800							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011031&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757168	103923726		CHEMBL333206				ZINC13861030	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016482	CCOC(=O)c1c(C)n(CC[C@@H]2C[C@@H](O)CC(=O)O2)c(c1-c1ccccc1)-c1ccccc1	InChI=1S/C27H29NO5/c1-3-32-27(31)24-18(2)28(15-14-22-16-21(29)17-23(30)33-22)26(20-12-8-5-9-13-20)25(24)19-10-6-4-7-11-19/h4-13,21-22,29H,3,14-17H2,1-2H3/t21-,22-/m1/s1	FOOCNRPUEZUTPF-FGZHOGPDSA-N	50011030	1-[2-(4-Hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-methyl-4,5-diphenyl-1H-pyrrole-3-carboxylic acid ethyl ester::CHEMBL123811	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4000							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011030	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011030&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757146	103923725		CHEMBL123811				ZINC13861017	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016483	CC(C)c1c(C)c(C)c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H28FNO3/c1-13(2)21-14(3)15(4)22(16-5-7-17(23)8-6-16)24(21)10-9-19-11-18(25)12-20(26)27-19/h5-8,13,18-19,25H,9-12H2,1-4H3/t18-,19-/m1/s1	KHNPIGQSDPPQFX-RTBURBONSA-N	50011033	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-3,4-dimethyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL331952	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 140							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011033	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011033&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757162	103923728		CHEMBL331952				ZINC13861025	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016484	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C33H33FN2O4/c1-21(2)31-30(33(39)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-27-19-26(37)20-28(38)40-27/h3-16,21,26-27,37H,17-20H2,1-2H3,(H,35,39)/t26-,27-/m1/s1	OUCSEDFVYPBLLF-KAYWLYCHSA-N	50011032	5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide::Atorvastatin lactone::CHEMBL333687::US9006282, Example 3, Compound 2	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.00							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011032	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011032&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6483036	103923727		CHEMBL333687		2957		ZINC03920720	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016485	CC(C)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-7-8-19(14-3-5-15(21)6-4-14)22(18)10-9-17-11-16(23)12-20(24)25-17/h3-8,13,16-17,23H,9-12H2,1-2H3/t16-,17-/m1/s1	ZYSGPNCFTPUHGN-IAGOWNOFSA-N	50011034	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104044	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 230							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011034	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011034&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785438	103923729		CHEMBL104044				ZINC13861016	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016487	CC(C)c1c(C(=O)OCc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C34H34FNO5/c1-22(2)32-31(34(39)40-21-23-9-5-3-6-10-23)30(24-11-7-4-8-12-24)33(25-13-15-26(35)16-14-25)36(32)18-17-28-19-27(37)20-29(38)41-28/h3-16,22,27-28,37H,17-21H2,1-2H3/t27-,28-/m1/s1	NPHAJEJFRVQYNE-VSGBNLITSA-N	50011035	5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid benzyl ester::CHEMBL331453	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 40							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011035	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011035&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14757158	103923730		CHEMBL331453				ZINC27193497	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016488	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016489	CC(C)c1nc2ccccc2c(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H24FNO3/c1-15(2)25-21(12-11-19-13-18(28)14-23(29)30-19)24(16-7-9-17(26)10-8-16)20-5-3-4-6-22(20)27-25/h3-12,15,18-19,28H,13-14H2,1-2H3/b12-11+/t18-,19-/m1/s1	IOTZDEROGUWISV-MCBHFWOFSA-N	50011037	6-{2-[4-(4-Fluoro-phenyl)-2-isopropyl-quinolin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL333933	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 32							ChEMBL	10.1021/jm00105a057	10.7270/Q2J38RHG	1992138			Sliskovic, DR; Picard, JA; Roark, WH; Roth, BD; Ferguson, E; Krause, BR; Newton, RS; Sekerke, C; Shaw, MK	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011037	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011037&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14229355	103923732		CHEMBL333933				ZINC01488611	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016490	CC(C)c1c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(-c2ccc(F)cc2)c2cc(F)ccc2[n+]1[O-]	InChI=1S/C25H23F2NO4/c1-14(2)25-20(9-8-19-12-18(29)13-23(30)32-19)24(15-3-5-16(26)6-4-15)21-11-17(27)7-10-22(21)28(25)31/h3-11,14,18-19,29H,12-13H2,1-2H3/b9-8+/t18-,19-/m1/s1	FUVIHYPTVRWEBX-TYFAACHXSA-N	50011038	6-{2-[6-Fluoro-4-(4-fluoro-phenyl)-2-isopropyl-1-oxy-quinolin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one(N-Oxide)::CHEMBL122937	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 79							ChEMBL	10.1021/jm00105a057	10.7270/Q2J38RHG	1992138			Sliskovic, DR; Picard, JA; Roark, WH; Roth, BD; Ferguson, E; Krause, BR; Newton, RS; Sekerke, C; Shaw, MK	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011038&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14780572	103923733		CHEMBL122937				ZINC13861032	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016491	CC(C)c1nc2ccc(Cl)cc2c(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H23ClFNO3/c1-14(2)25-20(9-8-19-12-18(29)13-23(30)31-19)24(15-3-6-17(27)7-4-15)21-11-16(26)5-10-22(21)28-25/h3-11,14,18-19,29H,12-13H2,1-2H3/b9-8+/t18-,19-/m1/s1	FRJJJAKBRKABFA-TYFAACHXSA-N	50011041	6-{2-[6-Chloro-4-(4-fluoro-phenyl)-2-isopropyl-quinolin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL333258	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25							ChEMBL	10.1021/jm00105a057	10.7270/Q2J38RHG	1992138			Sliskovic, DR; Picard, JA; Roark, WH; Roth, BD; Ferguson, E; Krause, BR; Newton, RS; Sekerke, C; Shaw, MK	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011041	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011041&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14229352	103923736		CHEMBL333258		2966		ZINC01488612	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016492	CN(C)c1nc2ccccc2c(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C24H23FN2O3/c1-27(2)24-20(12-11-18-13-17(28)14-22(29)30-18)23(15-7-9-16(25)10-8-15)19-5-3-4-6-21(19)26-24/h3-12,17-18,28H,13-14H2,1-2H3/b12-11+/t17-,18-/m1/s1	GXLANZMAZGVTDX-LLSOJIOMSA-N	50011042	6-{2-[2-Dimethylamino-4-(4-fluoro-phenyl)-quinolin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL122947	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 350							ChEMBL	10.1021/jm00105a057	10.7270/Q2J38RHG	1992138			Sliskovic, DR; Picard, JA; Roark, WH; Roth, BD; Ferguson, E; Krause, BR; Newton, RS; Sekerke, C; Shaw, MK	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011042&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14780588	103923737		CHEMBL122947				ZINC13861033	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016493	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19?,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-KVVRZSONSA-N	50004774	(S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-((R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::(lovastatin)2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(mevinolin)::CHEMBL503	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 28							ChEMBL	10.1021/jm00105a057	10.7270/Q2J38RHG	1992138			Sliskovic, DR; Picard, JA; Roark, WH; Roth, BD; Ferguson, E; Krause, BR; Newton, RS; Sekerke, C; Shaw, MK	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004774&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6420024	103918321		CHEMBL503				ZINC04245664	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016494	COc1ccc2nc(C(C)C)c(\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)c(-c3ccc(F)cc3)c2c1	InChI=1S/C26H26FNO4/c1-15(2)26-21(10-8-20-12-18(29)13-24(30)32-20)25(16-4-6-17(27)7-5-16)22-14-19(31-3)9-11-23(22)28-26/h4-11,14-15,18,20,29H,12-13H2,1-3H3/b10-8+/t18-,20-/m1/s1	KCOGCSKFAXCWES-YLJGDWCDSA-N	50011039	6-{2-[4-(4-Fluoro-phenyl)-2-isopropyl-6-methoxy-quinolin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL122112	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 53.0							ChEMBL	10.1021/jm00105a057	10.7270/Q2J38RHG	1992138			Sliskovic, DR; Picard, JA; Roark, WH; Roth, BD; Ferguson, E; Krause, BR; Newton, RS; Sekerke, C; Shaw, MK	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011039&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14780602	103923734		CHEMBL122112				ZINC03797408	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016495	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25							ChEMBL	10.1021/jm00105a057	10.7270/Q2J38RHG	1992138			Sliskovic, DR; Picard, JA; Roark, WH; Roth, BD; Ferguson, E; Krause, BR; Newton, RS; Sekerke, C; Shaw, MK	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016496	Cc1nc2ccc(Cl)cc2c(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C23H19ClFNO3/c1-13-19(8-7-18-11-17(27)12-22(28)29-18)23(14-2-5-16(25)6-3-14)20-10-15(24)4-9-21(20)26-13/h2-10,17-18,27H,11-12H2,1H3/b8-7+/t17-,18-/m1/s1	WRMOSELMQIYDOA-HNGSOEQISA-N	50011045	6-{2-[6-Chloro-4-(4-fluoro-phenyl)-2-methyl-quinolin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL334113	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 720							ChEMBL	10.1021/jm00105a057	10.7270/Q2J38RHG	1992138			Sliskovic, DR; Picard, JA; Roark, WH; Roth, BD; Ferguson, E; Krause, BR; Newton, RS; Sekerke, C; Shaw, MK	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011045	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011045&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14229341	103923738		CHEMBL334113				ZINC03782959	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016497	CC(C)c1nc2ccc(F)cc2c(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H23F2NO3/c1-14(2)25-20(9-8-19-12-18(29)13-23(30)31-19)24(15-3-5-16(26)6-4-15)21-11-17(27)7-10-22(21)28-25/h3-11,14,18-19,29H,12-13H2,1-2H3/b9-8+/t18-,19-/m1/s1	XDKQXVMPRDYWHY-TYFAACHXSA-N	50011040	6-{2-[6-Fluoro-4-(4-fluoro-phenyl)-2-isopropyl-quinolin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL123082	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 200							ChEMBL	10.1021/jm00105a057	10.7270/Q2J38RHG	1992138			Sliskovic, DR; Picard, JA; Roark, WH; Roth, BD; Ferguson, E; Krause, BR; Newton, RS; Sekerke, C; Shaw, MK	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011040	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011040&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14780570	103923735		CHEMBL123082				ZINC03797411	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019365	CC(C)c1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(cn1C(C)C)-c1ccc(F)cc1	InChI=1S/C23H30FNO4/c1-14(2)23-20(10-9-18(26)11-19(27)12-22(28)29)21(13-25(23)15(3)4)16-5-7-17(24)8-6-16/h5-10,13-15,18-19,26-27H,11-12H2,1-4H3,(H,28,29)/p-1/b10-9+/t18-,19-/m1/s1	JNPGUXGVLNJQSQ-BGGMYYEUSA-M	50013212	CHEMBL160102::Sodium salt of7-[4-(4-Fluoro-phenyl)-1,2-diisopropyl-1H-pyrrol-3-yl]-3,5-dihydroxy-hept-6-enoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 117							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013212&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947035	103925427		CHEMBL160102			C03834	ZINC27762184	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019368	CC(C)c1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)n1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C27H30FNO4/c1-17(2)27-24(14-13-22(30)15-23(31)16-25(32)33)26(19-9-11-20(28)12-10-19)18(3)29(27)21-7-5-4-6-8-21/h4-14,17,22-23,30-31H,15-16H2,1-3H3,(H,32,33)/p-1/b14-13+/t22-,23-/m1/s1	IDWYYPAGRYYRQC-OKRGKCMKSA-M	50013213	CHEMBL350103::Sodium salt of7-[4-(4-Fluoro-phenyl)-2-isopropyl-5-methyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-hept-6-enoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013213	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013213&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928863	103925428		CHEMBL350103			C03834	ZINC27747697	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019371	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(cn1C(C)C)-c1ccc(F)cc1	InChI=1S/C23H32FNO4/c1-14(2)23-20(10-9-18(26)11-19(27)12-22(28)29)21(13-25(23)15(3)4)16-5-7-17(24)8-6-16/h5-8,13-15,18-19,26-27H,9-12H2,1-4H3,(H,28,29)/p-1/t18-,19-/m1/s1	VJZPFDQBVJSLEQ-RTBURBONSA-M	50013216	(racemic)Sodium salt of7-[4-(4-Fluoro-phenyl)-1,2-diisopropyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoic acid::CHEMBL348798::Sodium salt of7-[4-(4-Fluoro-phenyl)-1,2-diisopropyl-1H-pyrrol-3-yl]-3R,5R-dihydroxy-heptanoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 18.0							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013216&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928864	103925431		CHEMBL348798			C03834	ZINC13887138	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019372	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)n1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C27H32FNO4/c1-17(2)27-24(14-13-22(30)15-23(31)16-25(32)33)26(19-9-11-20(28)12-10-19)18(3)29(27)21-7-5-4-6-8-21/h4-12,17,22-23,30-31H,13-16H2,1-3H3,(H,32,33)/p-1/t22-,23-/m1/s1	JHURQXGATCGLIV-DHIUTWEWSA-M	50013214	(racemic)Sodium salt of7-[4-(4-Fluoro-phenyl)-2-isopropyl-5-methyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoic acid::CHEMBL436037::Sodium salt of7-[4-(4-Fluoro-phenyl)-2-isopropyl-5-methyl-1-phenyl-1H-pyrrol-3-yl]-3R,5R-dihydroxy-heptanoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013214&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947028	103925429		CHEMBL436037			C03834	ZINC27747847	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019373	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19?,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-KVVRZSONSA-N	50004774	(S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-((R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::(lovastatin)2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(mevinolin)::CHEMBL503	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004774&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6420024	103918321		CHEMBL503				ZINC04245664	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019374	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(cn1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C26H30FNO4/c1-17(2)26-23(13-12-21(29)14-22(30)15-25(31)32)24(18-8-10-19(27)11-9-18)16-28(26)20-6-4-3-5-7-20/h3-11,16-17,21-22,29-30H,12-15H2,1-2H3,(H,31,32)/p-1/t21-,22-/m1/s1	UBFHWBHHCSSZAB-FGZHOGPDSA-M	50013211	(racemic)Sodium salt of7-[4-(4-Fluoro-phenyl)-2-isopropyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoic acid::CHEMBL162125::Sodium salt of7-[4-(4-Fluoro-phenyl)-2-isopropyl-1-phenyl-1H-pyrrol-3-yl]-3R,5R-dihydroxy-heptanoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013211	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013211&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947025	103925426		CHEMBL162125			C03834	ZINC13824755	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019375	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(cn1C1CCCCC1)-c1ccc(F)cc1	InChI=1S/C26H36FNO4/c1-17(2)26-23(13-12-21(29)14-22(30)15-25(31)32)24(18-8-10-19(27)11-9-18)16-28(26)20-6-4-3-5-7-20/h8-11,16-17,20-22,29-30H,3-7,12-15H2,1-2H3,(H,31,32)/p-1/t21-,22-/m1/s1	RODBEKUWCLMBSW-FGZHOGPDSA-M	50013217	CHEMBL159951::Sodium salt of7-[1-Cyclohexyl-4-(4-fluoro-phenyl)-2-isopropyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013217&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947023	103925432		CHEMBL159951			C03834	ZINC13887135	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019376	CC(C)n1cc(c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c1C)-c1ccc(F)cc1	InChI=1S/C21H26FNO4/c1-13(2)23-12-20(15-4-6-16(22)7-5-15)19(14(23)3)9-8-17(24)10-18(25)11-21(26)27/h4-9,12-13,17-18,24-25H,10-11H2,1-3H3,(H,26,27)/p-1/b9-8+/t17-,18-/m1/s1	HXBKHTSJLRQDIB-RKQNLGICSA-M	50013218	CHEMBL345375::Sodium salt of7-[4-(4-Fluoro-phenyl)-1-isopropyl-2-methyl-1H-pyrrol-3-yl]-3,5-dihydroxy-hept-6-enoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 330							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013218	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013218&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928865	103925433		CHEMBL345375			C03834	ZINC27732911	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019378	[Na+].CC(C)c1c(\C=C\[C@H](O)C[C@@H](O)CC([O-])=O)c(cn1C1CCCCC1)-c1ccc(F)cc1	InChI=1S/C26H34FNO4.Na/c1-17(2)26-23(13-12-21(29)14-22(30)15-25(31)32)24(18-8-10-19(27)11-9-18)16-28(26)20-6-4-3-5-7-20;/h8-13,16-17,20-22,29-30H,3-7,14-15H2,1-2H3,(H,31,32);/q;+1/p-1/b13-12+;/t21-,22+;/m0./s1	MEBHTQYJINYGAN-XECPIYGWSA-M	50013219	CHEMBL2375155::Sodium salt of7-[1-Cyclohexyl-4-(4-fluoro-phenyl)-2-isopropyl-1H-pyrrol-3-yl]-3,5-dihydroxy-hept-6-enoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 0.106							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013219	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013219&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73347269	103925434		CHEMBL2375155				ZINC27748657	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019380	[Na+].Cc1c(\C=C\[C@H](O)C[C@@H](O)CC([O-])=O)c(cn1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C24H24FNO4.Na/c1-16-22(12-11-20(27)13-21(28)14-24(29)30)23(17-7-9-18(25)10-8-17)15-26(16)19-5-3-2-4-6-19;/h2-12,15,20-21,27-28H,13-14H2,1H3,(H,29,30);/q;+1/p-1/b12-11+;/t20-,21+;/m0./s1	VFFDESJHNSVRML-DFVOXZGXSA-M	50013215	CHEMBL2375156::Sodium salt of7-[4-(4-Fluoro-phenyl)-2-methyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-hept-6-enoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 65							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013215	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013215&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345785	103925430		CHEMBL2375156				ZINC27760288	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019383	CC(C)n1cc(c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1C)-c1ccc(F)cc1	InChI=1S/C21H28FNO4/c1-13(2)23-12-20(15-4-6-16(22)7-5-15)19(14(23)3)9-8-17(24)10-18(25)11-21(26)27/h4-7,12-13,17-18,24-25H,8-11H2,1-3H3,(H,26,27)/p-1/t17-,18-/m1/s1	LJBGBXVAGFAMLZ-QZTJIDSGSA-M	50013221	CHEMBL163277::Sodium salt of7-[4-(4-Fluoro-phenyl)-1-isopropyl-2-methyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013221	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013221&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947027	103925436		CHEMBL163277			C03834	ZINC27761091	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019384	CC(C)c1c(CCC(O)C[C@@H](O)CC([O-])=O)c(cn1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C26H30FNO4/c1-17(2)26-23(13-12-21(29)14-22(30)15-25(31)32)24(18-8-10-19(27)11-9-18)16-28(26)20-6-4-3-5-7-20/h3-11,16-17,21-22,29-30H,12-15H2,1-2H3,(H,31,32)/p-1/t21?,22-/m1/s1	UBFHWBHHCSSZAB-FOIFJWKZSA-M	50007261	CHEMBL102091::Sodium; 7-[4-(4-fluoro-phenyl)-2-isopropyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007261&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928754	103920541		CHEMBL102091			C03834	ZINC13887133	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019387	Cc1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)n1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C25H28FNO4/c1-16-23(13-12-21(28)14-22(29)15-24(30)31)25(18-8-10-19(26)11-9-18)17(2)27(16)20-6-4-3-5-7-20/h3-11,21-22,28-29H,12-15H2,1-2H3,(H,30,31)/p-1/t21-,22-/m1/s1	QKLXBIHSGMPUQS-FGZHOGPDSA-M	50013220	CHEMBL161829::Sodium salt of7-[4-(4-Fluoro-phenyl)-2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 70							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013220	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013220&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947026	103925435		CHEMBL161829			C03834	ZINC13824753	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019391	Cc1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)n1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C25H26FNO4/c1-16-23(13-12-21(28)14-22(29)15-24(30)31)25(18-8-10-19(26)11-9-18)17(2)27(16)20-6-4-3-5-7-20/h3-13,21-22,28-29H,14-15H2,1-2H3,(H,30,31)/p-1/b13-12+/t21-,22-/m1/s1	WNFLCKCKUBDEAY-ITWZMISCSA-M	50013222	CHEMBL159103::Sodium salt of7-[4-(4-Fluoro-phenyl)-2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-hept-6-enoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 250							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013222	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013222&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928866	103925437		CHEMBL159103			C03834	ZINC27732903	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019392	CC(C)c1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(cn1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C26H28FNO4/c1-17(2)26-23(13-12-21(29)14-22(30)15-25(31)32)24(18-8-10-19(27)11-9-18)16-28(26)20-6-4-3-5-7-20/h3-13,16-17,21-22,29-30H,14-15H2,1-2H3,(H,31,32)/p-1/b13-12+/t21-,22-/m1/s1	VAVHMEQFYYBAPR-ITWZMISCSA-M	50013210	CHEMBL162642::Sodium salt of 7-[4-(4-Fluoro-phenyl)-2-isopropyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-hept-6-enoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013210	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013210&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928862	103925425		CHEMBL162642			C03834	ZINC11688768	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021732	CC(C)c1nn(Cc2ccccc2)c(c1CC[C@H]1C[C@H](O)CC(=O)O1)-c1ccc(F)cc1	InChI=1S/C26H29FN2O3/c1-17(2)25-23(13-12-22-14-21(30)15-24(31)32-22)26(19-8-10-20(27)11-9-19)29(28-25)16-18-6-4-3-5-7-18/h3-11,17,21-22,30H,12-16H2,1-2H3/t21-,22-/m0/s1	SFTVYVGIXNZCEX-VXKWHMMOSA-N	50014719	6-{2-[1-Benzyl-5-(4-fluoro-phenyl)-3-isopropyl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL340848	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 158							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014719&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349330	103926614		CHEMBL340848		2964		ZINC27210964	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021733	CC(C)c1nn(c(c1CC[C@H]1C[C@H](O)CC(=O)O1)-c1ccc(F)cc1)-c1cccc2ccccc12	InChI=1S/C29H29FN2O3/c1-18(2)28-25(15-14-23-16-22(33)17-27(34)35-23)29(20-10-12-21(30)13-11-20)32(31-28)26-9-5-7-19-6-3-4-8-24(19)26/h3-13,18,22-23,33H,14-17H2,1-2H3/t22-,23-/m0/s1	GYYJFSUCOWTMHG-GOTSBHOMSA-N	50014720	6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-naphthalen-1-yl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL340139	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 234							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014720&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349355	103926615		CHEMBL340139				ZINC27216923	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021734	CC(C)c1nn(c(c1C(=C)[C@H]1C[C@H](O)CC(=O)O1)-c1ccc(F)cc1)-c1ccccc1	InChI=1S/C25H25FN2O3/c1-15(2)24-23(16(3)21-13-20(29)14-22(30)31-21)25(17-9-11-18(26)12-10-17)28(27-24)19-7-5-4-6-8-19/h4-12,15,20-21,29H,3,13-14H2,1-2H3/t20-,21+/m0/s1	YQXVZSSJYRTNCJ-LEWJYISDSA-N	50014721	6-{1-[5-(4-Fluoro-phenyl)-3-isopropyl-1-phenyl-1H-pyrazol-4-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL125924	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 17800							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014721&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349331	103926616		CHEMBL125924				ZINC27210967	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021735	COc1ccc(cc1)-n1nc(C(C)C)c(CC[C@H]2C[C@H](O)CC(=O)O2)c1-c1ccc(F)cc1	InChI=1S/C26H29FN2O4/c1-16(2)25-23(13-12-22-14-20(30)15-24(31)33-22)26(17-4-6-18(27)7-5-17)29(28-25)19-8-10-21(32-3)11-9-19/h4-11,16,20,22,30H,12-15H2,1-3H3/t20-,22-/m0/s1	GTYFHOQZYKMYHJ-UNMCSNQZSA-N	50014722	6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-(4-methoxy-phenyl)-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL332057	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 39							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014722&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349253	103926617		CHEMBL332057				ZINC27212148	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021736	CC(C)c1nn(c(c1CC[C@H]1C[C@H](O)CC(=O)O1)-c1ccc(F)cc1)S(=O)(=O)c1ccc(C)cc1	InChI=1S/C26H29FN2O5S/c1-16(2)25-23(13-10-21-14-20(30)15-24(31)34-21)26(18-6-8-19(27)9-7-18)29(28-25)35(32,33)22-11-4-17(3)5-12-22/h4-9,11-12,16,20-21,30H,10,13-15H2,1-3H3/t20-,21-/m0/s1	ZWURXLIJEHYPGT-SFTDATJTSA-N	50014723	6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-(toluene-4-sulfonyl)-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL341284	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 660.0							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014723	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014723&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349320	103926618		CHEMBL341284				ZINC27211434	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021737	CC(C)c1nn(c(c1CC[C@@H]1C[C@H](O)CC(=O)O1)-c1ccc(F)cc1)-c1ccccc1	InChI=1S/C25H27FN2O3/c1-16(2)24-22(13-12-21-14-20(29)15-23(30)31-21)25(17-8-10-18(26)11-9-17)28(27-24)19-6-4-3-5-7-19/h3-11,16,20-21,29H,12-15H2,1-2H3/t20-,21+/m0/s1	GTJZNUCKMJCREJ-LEWJYISDSA-N	50014725	6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-phenyl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL127924	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 700							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014725&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349338	103926620		CHEMBL127924				ZINC27216881	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021738	CO[C@H]1C[C@H](CCc2c(nn(c2-c2ccc(F)cc2)-c2ccccc2)C(C)C)OC(=O)C1	InChI=1S/C26H29FN2O3/c1-17(2)25-23(14-13-21-15-22(31-3)16-24(30)32-21)26(18-9-11-19(27)12-10-18)29(28-25)20-7-5-4-6-8-20/h4-12,17,21-22H,13-16H2,1-3H3/t21-,22-/m0/s1	LTYDXOIVNZIRJH-VXKWHMMOSA-N	50014724	6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-phenyl-1H-pyrazol-4-yl]-ethyl}-4-methoxy-tetrahydro-pyran-2-one::CHEMBL125426	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3160							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014724&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349334	103926619		CHEMBL125426				ZINC27208402	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021739	CC(C)c1nn(c(c1CC[C@H]1C[C@H](O)CC(=O)O1)-c1ccc(F)cc1)-c1ccc(C)cc1	InChI=1S/C26H29FN2O3/c1-16(2)25-23(13-12-22-14-21(30)15-24(31)32-22)26(18-6-8-19(27)9-7-18)29(28-25)20-10-4-17(3)5-11-20/h4-11,16,21-22,30H,12-15H2,1-3H3/t21-,22-/m0/s1	LADHLWZPKSCVFY-VXKWHMMOSA-N	50014727	6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-p-tolyl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL338993	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 40							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014727&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349252	103926622		CHEMBL338993				ZINC27211895	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021740	CC(C)c1nn(c(c1CC[C@H]1C[C@H](O)CC(=O)O1)-c1ccc(F)cc1)-c1ccccc1	InChI=1S/C25H27FN2O3/c1-16(2)24-22(13-12-21-14-20(29)15-23(30)31-21)25(17-8-10-18(26)11-9-17)28(27-24)19-6-4-3-5-7-19/h3-11,16,20-21,29H,12-15H2,1-2H3/t20-,21-/m0/s1	GTJZNUCKMJCREJ-SFTDATJTSA-N	50014726	6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-phenyl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL434433	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 35							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014726&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349176	103926621		CHEMBL434433				ZINC27209760	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021741	CC(C)c1nn(c(c1CCC1CC(=O)CC(=O)O1)-c1ccc(F)cc1)-c1ccccc1	InChI=1S/C25H25FN2O3/c1-16(2)24-22(13-12-21-14-20(29)15-23(30)31-21)25(17-8-10-18(26)11-9-17)28(27-24)19-6-4-3-5-7-19/h3-11,16,21H,12-15H2,1-2H3	FLLTWRLSCMMDTF-UHFFFAOYSA-N	50014728	6-{2-[5-(4-Fluoro-phenyl)-3-isopropyl-1-phenyl-1H-pyrazol-4-yl]-ethyl}-dihydro-pyran-2,4-dione::CHEMBL127836	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10000							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014728&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349339	103926623		CHEMBL127836				ZINC27216888	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021742	CC(C)c1nn(c(c1CC[C@H]1C[C@H](O)CC(=O)O1)-c1ccc(F)cc1)-c1ccc(F)cc1	InChI=1S/C25H26F2N2O3/c1-15(2)24-22(12-11-21-13-20(30)14-23(31)32-21)25(16-3-5-17(26)6-4-16)29(28-24)19-9-7-18(27)8-10-19/h3-10,15,20-21,30H,11-14H2,1-2H3/t20-,21-/m0/s1	CJOOCCJIHMSWOT-SFTDATJTSA-N	50014729	6-{2-[1,5-Bis-(4-fluoro-phenyl)-3-isopropyl-1H-pyrazol-4-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL421614	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 32							ChEMBL	10.1021/jm00163a006	10.7270/Q2B56HQB	2296027			Sliskovic, DR; Roth, BD; Wilson, MW; Hoefle, ML; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014729&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44349317	103926624		CHEMBL421614		2965		ZINC27215919	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021859	CCc1nc(cc(-c2ccc(F)cc2)c1CCC1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C26H26FNO3/c1-2-24-22(13-12-21-14-20(29)15-26(30)31-21)23(17-8-10-19(27)11-9-17)16-25(28-24)18-6-4-3-5-7-18/h3-11,16,20-21,29H,2,12-15H2,1H3/t20-,21?/m1/s1	PNHBRYIAJCYNDA-VQCQRNETSA-N	50014816	6-{2-[2-Ethyl-4-(4-fluoro-phenyl)-6-phenyl-pyridin-3-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL350895	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014816&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370460	103926711		CHEMBL350895		2969		ZINC27710082	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021863	CC(C)c1cc(-c2ccc(F)cc2)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(n1)C(C)C	InChI=1S/C24H28FNO3/c1-14(2)22-13-21(16-5-7-17(25)8-6-16)20(24(26-22)15(3)4)10-9-19-11-18(27)12-23(28)29-19/h5-10,13-15,18-19,27H,11-12H2,1-4H3/b10-9+/t18-,19-/m1/s1	KRMZQAVPDOZLBC-BGGMYYEUSA-N	50014819	(E)-6-{2-[6-tert-Butyl-4-(4-fluoro-phenyl)-2-isopropyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368187	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014819&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14460206	103926714		CHEMBL2368187		2971		ZINC27655217	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021865	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C26H25FN2O3/c1-16(2)24-22(13-12-21-14-20(30)15-23(31)32-21)25(17-8-10-19(27)11-9-17)29-26(28-24)18-6-4-3-5-7-18/h3-13,16,20-21,30H,14-15H2,1-2H3/b13-12+/t20-,21-/m1/s1	BMWVQIDFJPMMIT-DDVDASKDSA-N	50014821	(E)-6-{2-[4-(4-Fluoro-phenyl)-6-isopropyl-2-phenyl-pyrimidin-5-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368188	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5.00							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014821&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14460221	103926716		CHEMBL2368188				ZINC27650595	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021866	COc1ccc(cc1)-c1cc(nc(C(C)C)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C28H29NO4/c1-18(2)28-24(14-13-23-15-21(30)16-27(31)33-23)25(19-9-11-22(32-3)12-10-19)17-26(29-28)20-7-5-4-6-8-20/h4-14,17-18,21,23,30H,15-16H2,1-3H3/b14-13+/t21-,23-/m1/s1	RHFOAKIAPXDZKW-DOZDWOLESA-N	50014822	(E)-4-Hydroxy-6-{2-[2-isopropyl-4-(4-methoxy-phenyl)-6-phenyl-pyridin-3-yl]-vinyl}-tetrahydro-pyran-2-one::CHEMBL2368194	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 150							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014822&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73355938	103926717		CHEMBL2368194				ZINC27657358	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021867	CC(C)c1nc(cc(-c2ccc(cc2)C(F)(F)F)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C28H26F3NO3/c1-17(2)27-23(13-12-22-14-21(33)15-26(34)35-22)24(16-25(32-27)19-6-4-3-5-7-19)18-8-10-20(11-9-18)28(29,30)31/h3-13,16-17,21-22,33H,14-15H2,1-2H3/b13-12+/t21-,22-/m1/s1	PHESDKOISSFXQV-ITWZMISCSA-N	50014823	(E)-4-Hydroxy-6-{2-[2-isopropyl-6-phenyl-4-(4-trifluoromethyl-phenyl)-pyridin-3-yl]-vinyl}-tetrahydro-pyran-2-one::CHEMBL2368193	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 36							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014823&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			67750966	103926718		CHEMBL2368193				ZINC27657354	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021871	Cc1cc(-c2ccc(Cl)cc2)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(C)n1	InChI=1S/C20H20ClNO3/c1-12-9-19(14-3-5-15(21)6-4-14)18(13(2)22-12)8-7-17-10-16(23)11-20(24)25-17/h3-9,16-17,23H,10-11H2,1-2H3/b8-7+/t16-,17-/m1/s1	YUDMEWWJTJHMSU-NXVGNOFTSA-N	50014827	(E)-6-{2-[4-(4-Chloro-phenyl)-2,6-dimethyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368196	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 94							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014827&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73351413	103926722		CHEMBL2368196				ZINC27655212	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021877	CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1cc(C)cc(C)c1	InChI=1S/C29H30FNO3/c1-17(2)29-25(10-9-24-14-23(32)15-28(33)34-24)26(20-5-7-22(30)8-6-20)16-27(31-29)21-12-18(3)11-19(4)13-21/h5-13,16-17,23-24,32H,14-15H2,1-4H3/b10-9+/t23-,24-/m1/s1	DHZUWDJSBKJOGJ-SLUIGLDYSA-N	50014829	(E)-6-{2-[6-(3,5-Dimethyl-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368204	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014829&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			67750911	103926724		CHEMBL2368204				ZINC27655704	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021879	Cc1nc(C)c(CCC2C[C@@H](O)CC(=O)O2)c(n1)-c1ccc(F)cc1	InChI=1S/C19H21FN2O3/c1-11-17(8-7-16-9-15(23)10-18(24)25-16)19(22-12(2)21-11)13-3-5-14(20)6-4-13/h3-6,15-16,23H,7-10H2,1-2H3/t15-,16?/m1/s1	ITYLRAWIKSIRJL-AAFJCEBUSA-N	50014830	6-{2-[4-(4-Fluoro-phenyl)-2,6-dimethyl-pyrimidin-5-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL158323	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1000							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014830&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370458	103926725		CHEMBL158323				ZINC27657968	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021880	CC(C)c1nc(C(C)C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(n1)-c1ccc(F)cc1	InChI=1S/C23H27FN2O3/c1-13(2)21-19(10-9-18-11-17(27)12-20(28)29-18)22(26-23(25-21)14(3)4)15-5-7-16(24)8-6-15/h5-10,13-14,17-18,27H,11-12H2,1-4H3/b10-9+/t17-,18-/m1/s1	UTOIEVWJKDLJGE-AQRBRUGDSA-N	50014837	(E)-6-{2-[4-(4-Fluoro-phenyl)-2,6-diisopropyl-pyrimidin-5-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368190	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.80							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014837&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348335	103926732		CHEMBL2368190		2972		ZINC27636325	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021882	CC(C)c1nc(cc(-c2ccc(F)cc2)c1CCC1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C27H28FNO3/c1-17(2)27-23(13-12-22-14-21(30)15-26(31)32-22)24(18-8-10-20(28)11-9-18)16-25(29-27)19-6-4-3-5-7-19/h3-11,16-17,21-22,30H,12-15H2,1-2H3/t21-,22?/m1/s1	QVBVQHTXLPNXEY-ZMFCMNQTSA-N	50014834	6-{2-[4-(4-Fluoro-phenyl)-2-isopropyl-6-phenyl-pyridin-3-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL156695	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 19							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014834&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370459	103926729		CHEMBL156695		2968		ZINC27710073	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021883	CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccc(F)cc1	InChI=1S/C27H25F2NO3/c1-16(2)27-23(12-11-22-13-21(31)14-26(32)33-22)24(17-3-7-19(28)8-4-17)15-25(30-27)18-5-9-20(29)10-6-18/h3-12,15-16,21-22,31H,13-14H2,1-2H3/b12-11+/t21-,22-/m1/s1	HTIWAOOZGHNHMJ-CXYUPCIPSA-N	50014826	(E)-6-{2-[4,6-Bis-(4-fluoro-phenyl)-2-isopropyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368202	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014826&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			67869344	103926721		CHEMBL2368202				ZINC27703837	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021884	Cc1nc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(n1)-c1ccc(F)cc1	InChI=1S/C19H19FN2O3/c1-11-17(8-7-16-9-15(23)10-18(24)25-16)19(22-12(2)21-11)13-3-5-14(20)6-4-13/h3-8,15-16,23H,9-10H2,1-2H3/b8-7+/t15-,16-/m1/s1	VGFPFOPNPWZGIC-XLBHYRNJSA-N	50014833	(E)-6-{2-[4-(4-Fluoro-phenyl)-2,6-dimethyl-pyrimidin-5-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368203	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 500							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014833&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14460219	103926728		CHEMBL2368203				ZINC27709650	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021887	CCc1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C26H24FNO3/c1-2-24-22(13-12-21-14-20(29)15-26(30)31-21)23(17-8-10-19(27)11-9-17)16-25(28-24)18-6-4-3-5-7-18/h3-13,16,20-21,29H,2,14-15H2,1H3/b13-12+/t20-,21-/m1/s1	JZCAAARUYARJOI-DDVDASKDSA-N	50014832	(E)-6-{2-[2-Ethyl-4-(4-fluoro-phenyl)-6-phenyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368195	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 40							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014832&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345302	103926727		CHEMBL2368195				ZINC27707615	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021889	Cc1nc(cc(-c2ccc(F)cc2)c1\C=C/[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C25H22FNO3/c1-16-22(12-11-21-13-20(28)14-25(29)30-21)23(17-7-9-19(26)10-8-17)15-24(27-16)18-5-3-2-4-6-18/h2-12,15,20-21,28H,13-14H2,1H3/b12-11-/t20-,21-/m1/s1	UHKYOMOXQPXMQY-HTQPURHSSA-N	50406107	CHEMBL2111238	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406107&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14460203	163355131		CHEMBL2111238				ZINC36761410	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021890	CC(C)c1cc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C27H26FNO3/c1-17(2)24-16-25(18-6-4-3-5-7-18)29-27(19-8-10-20(28)11-9-19)23(24)13-12-22-14-21(30)15-26(31)32-22/h3-13,16-17,21-22,30H,14-15H2,1-2H3/b13-12+/t21-,22-/m1/s1	YLQGWEPVRMDOKD-ITWZMISCSA-N	50014839	(E)-6-{2-[2-(4-Fluoro-phenyl)-4-isopropyl-6-phenyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368200	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10.00							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014839&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			67869518	103926734		CHEMBL2368200				ZINC27656995	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021891	Cc1cc(-c2ccc(F)cc2)c(\C=C/[C@@H]2C[C@@H](O)CC(=O)O2)c(C)n1	InChI=1S/C20H20FNO3/c1-12-9-19(14-3-5-15(21)6-4-14)18(13(2)22-12)8-7-17-10-16(23)11-20(24)25-17/h3-9,16-17,23H,10-11H2,1-2H3/b8-7-/t16-,17-/m1/s1	ANOPSFFNQJWFSF-PMKBXARWSA-N	50406103	CHEMBL2111239	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406103	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406103&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14460199	163355127		CHEMBL2111239				ZINC36761404	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021892	CC(C)c1nc(C)cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H24FNO3/c1-13(2)22-19(9-8-18-11-17(25)12-21(26)27-18)20(10-14(3)24-22)15-4-6-16(23)7-5-15/h4-10,13,17-18,25H,11-12H2,1-3H3/b9-8+/t17-,18-/m1/s1	ROSRAJDGGIMAJE-RKQNLGICSA-N	50014836	(E)-6-{2-[4-(4-Fluoro-phenyl)-2-isopropyl-6-methyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368198	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014836&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352867	103926731		CHEMBL2368198				ZINC27656615	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021894	CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)C(C)(C)C	InChI=1S/C25H30FNO3/c1-15(2)24-20(11-10-19-12-18(28)13-23(29)30-19)21(14-22(27-24)25(3,4)5)16-6-8-17(26)9-7-16/h6-11,14-15,18-19,28H,12-13H2,1-5H3/b11-10+/t18-,19-/m1/s1	VPMIAOSOTOODMY-MMKWGKFASA-N	50014840	(E)-6-{2-[4-(4-Fluoro-phenyl)-2,6-diisopropyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368197	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014840	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014840&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14460209	103926735		CHEMBL2368197				ZINC27647540	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021895	CC(C)(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C28H28FNO3/c1-28(2,3)27-23(14-13-22-15-21(31)16-26(32)33-22)24(18-9-11-20(29)12-10-18)17-25(30-27)19-7-5-4-6-8-19/h4-14,17,21-22,31H,15-16H2,1-3H3/b14-13+/t21-,22-/m1/s1	QLFJBQCFNCGPCF-WRBWEIJPSA-N	50014838	(E)-6-{2-[4-(4-Fluoro-phenyl)-2-isopropyl-6-phenyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368192	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 18							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014838&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345301	103926733		CHEMBL2368192				ZINC27656386	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021897	CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1cc(C)ccc1C	InChI=1S/C29H30FNO3/c1-17(2)29-24(12-11-23-14-22(32)15-28(33)34-23)26(20-7-9-21(30)10-8-20)16-27(31-29)25-13-18(3)5-6-19(25)4/h5-13,16-17,22-23,32H,14-15H2,1-4H3/b12-11+/t22-,23-/m1/s1	CEFUFHDOLDUHBA-IJIRNXSHSA-N	50014835	(E)-6-{2-[6-(2,5-Dimethyl-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368205	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014835&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			67869066	103926730		CHEMBL2368205				ZINC27655710	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021898	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccc(F)cc1	InChI=1S/C26H24F2N2O3/c1-15(2)24-22(12-11-21-13-20(31)14-23(32)33-21)25(16-3-7-18(27)8-4-16)30-26(29-24)17-5-9-19(28)10-6-17/h3-12,15,20-21,31H,13-14H2,1-2H3/b12-11+/t20-,21-/m1/s1	HNLJLKKZTYTOJO-LKWCPCFXSA-N	50014828	(E)-6-{2-[2,4-Bis-(4-fluoro-phenyl)-6-isopropyl-pyrimidin-5-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368185	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014828&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354373	103926723		CHEMBL2368185				ZINC27653484	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021901	CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C27H26FNO3/c1-17(2)27-23(13-12-22-14-21(30)15-26(31)32-22)24(18-8-10-20(28)11-9-18)16-25(29-27)19-6-4-3-5-7-19/h3-13,16-17,21-22,30H,14-15H2,1-2H3/b13-12+/t21-,22-/m1/s1	LJIZUXQINHXGAO-ITWZMISCSA-N	50014841	(E)-6-{2-[2-tert-Butyl-4-(4-fluoro-phenyl)-6-phenyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368199	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014841	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014841&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			5281970	103926736		CHEMBL2368199			C11699	ZINC27651811	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021902	CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)C1CCCCC1	InChI=1S/C27H32FNO3/c1-17(2)27-23(13-12-22-14-21(30)15-26(31)32-22)24(18-8-10-20(28)11-9-18)16-25(29-27)19-6-4-3-5-7-19/h8-13,16-17,19,21-22,30H,3-7,14-15H2,1-2H3/b13-12+/t21-,22-/m1/s1	HBGOTWCUTKTDHB-ITWZMISCSA-N	50014831	(E)-6-{2-[6-Cyclohexyl-4-(4-fluoro-phenyl)-2-isopropyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368191	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014831&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14460211	103926726		CHEMBL2368191				ZINC27708142	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021903	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)C1CCCCC1	InChI=1S/C26H31FN2O3/c1-16(2)24-22(13-12-21-14-20(30)15-23(31)32-21)25(17-8-10-19(27)11-9-17)29-26(28-24)18-6-4-3-5-7-18/h8-13,16,18,20-21,30H,3-7,14-15H2,1-2H3/b13-12+/t20-,21-/m1/s1	TUUVFNSQWXOUDX-DDVDASKDSA-N	50014820	(E)-6-{2-[2-Cyclohexyl-4-(4-fluoro-phenyl)-6-isopropyl-pyrimidin-5-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368189	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014820&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352866	103926715		CHEMBL2368189				ZINC27650937	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50021906	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(nc(cc1-c1ccc(F)cc1)-c1ccccc1)C1CCCCC1	InChI=1S/C30H30FNO3/c31-23-13-11-20(12-14-23)27-19-28(21-7-3-1-4-8-21)32-30(22-9-5-2-6-10-22)26(27)16-15-25-17-24(33)18-29(34)35-25/h1,3-4,7-8,11-16,19,22,24-25,33H,2,5-6,9-10,17-18H2/b16-15+/t24-,25-/m1/s1	RLORTZFLTXGQMX-MOCODALISA-N	50014818	(E)-6-{2-[2-Cyclohexyl-4-(4-fluoro-phenyl)-6-phenyl-pyridin-3-yl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368201	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014818&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14460213	103926713		CHEMBL2368201				ZINC27656999	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022079	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccc(Br)c2ccccc12	InChI=1S/C17H15BrO3/c18-16-8-6-11(14-3-1-2-4-15(14)16)5-7-13-9-12(19)10-17(20)21-13/h1-8,12-13,19H,9-10H2/b7-5+/t12-,13-/m1/s1	ZBMMHOBZFMPSQP-MVTQWGDUSA-N	50014947	6-[2-(4-Bromo-naphthalen-1-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368309	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4000							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014947	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014947&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354380	103926821		CHEMBL2368309				ZINC27878318	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022080	Cc1cc(C)c2ccc(Cl)cc2c1CCC1C[C@@H](O)CC(=O)O1	InChI=1S/C19H21ClO3/c1-11-7-12(2)17(18-8-13(20)3-5-16(11)18)6-4-15-9-14(21)10-19(22)23-15/h3,5,7-8,14-15,21H,4,6,9-10H2,1-2H3/t14-,15?/m1/s1	FUQMTWMTRYCUOK-GICMACPYSA-N	50014948	6-[2-(7-Chloro-2,4-dimethyl-naphthalen-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL164761	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 200							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014948	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014948&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44377977	103926822		CHEMBL164761				ZINC27869469	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022081	O[C@@H]1CC(CCc2c(Cl)cc(Cl)c3cc(Cl)ccc23)OC(=O)C1	InChI=1S/C17H15Cl3O3/c18-9-1-3-12-13(15(19)8-16(20)14(12)5-9)4-2-11-6-10(21)7-17(22)23-11/h1,3,5,8,10-11,21H,2,4,6-7H2/t10-,11?/m1/s1	ZWTXDHXYESDLCS-NFJWQWPMSA-N	50014949	4-Hydroxy-6-[2-(2,4,6-trichloro-naphthalen-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL424166	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 33							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014949	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014949&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44378355	103926823		CHEMBL424166				ZINC27872975	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022082	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)ccc2ccccc12	InChI=1S/C17H15ClO3/c18-16-8-5-11-3-1-2-4-14(11)15(16)7-6-13-9-12(19)10-17(20)21-13/h1-8,12-13,19H,9-10H2/b7-6+/t12-,13-/m1/s1	DVUKAFYKBOGQDC-AMRKSYTLSA-N	50014950	6-[2-(2-Chloro-naphthalen-1-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368308	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1510							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014950	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014950&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354379	103926824		CHEMBL2368308				ZINC27865177	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022083	O[C@@H]1CC(CCc2ccc(Br)c3ccccc23)OC(=O)C1	InChI=1S/C17H17BrO3/c18-16-8-6-11(14-3-1-2-4-15(14)16)5-7-13-9-12(19)10-17(20)21-13/h1-4,6,8,12-13,19H,5,7,9-10H2/t12-,13?/m1/s1	PUSPAFQBBUKRQF-PZORYLMUSA-N	50014951	6-[2-(4-Bromo-naphthalen-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL353120	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 23300							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014951	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014951&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44377902	103926825		CHEMBL353120				ZINC27868579	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022084	O[C@@H]1CC(CCc2cccc3ccccc23)OC(=O)C1	InChI=1S/C17H18O3/c18-14-10-15(20-17(19)11-14)9-8-13-6-3-5-12-4-1-2-7-16(12)13/h1-7,14-15,18H,8-11H2/t14-,15?/m1/s1	APQYISHFWANGRJ-GICMACPYSA-N	50014952	4-Hydroxy-6-(2-naphthalen-1-yl-ethyl)-tetrahydro-pyran-2-one::CHEMBL118866	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 81000							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014952	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014952&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44345838	103926826		CHEMBL118866				ZINC27107527	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022085	O[C@@H]1CC(CCc2ccc(Cl)c3cc(Cl)ccc23)OC(=O)C1	InChI=1S/C17H16Cl2O3/c18-11-3-5-14-10(2-6-16(19)15(14)7-11)1-4-13-8-12(20)9-17(21)22-13/h2-3,5-7,12-13,20H,1,4,8-9H2/t12-,13?/m1/s1	CFDKIOXRIIIRNK-PZORYLMUSA-N	50014953	6-[2-(4,6-Dichloro-naphthalen-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL164056	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7000							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014953	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014953&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44377963	103926827		CHEMBL164056				ZINC27871028	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022086	Cc1cc(Cl)c(CCC2C[C@@H](O)CC(=O)O2)c2cc(Cl)ccc12	InChI=1S/C18H18Cl2O3/c1-10-6-17(20)15(16-7-11(19)2-4-14(10)16)5-3-13-8-12(21)9-18(22)23-13/h2,4,6-7,12-13,21H,3,5,8-9H2,1H3/t12-,13?/m1/s1	SRYPHCHHXWZMKS-PZORYLMUSA-N	50014954	6-[2-(2,7-Dichloro-4-methyl-naphthalen-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL350733	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 130							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014954	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014954&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44377964	103926828		CHEMBL350733				ZINC27871041	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022087	O[C@@H]1CC(CCc2c(Cl)cc(Cl)c3ccc(Cl)cc23)OC(=O)C1	InChI=1S/C17H15Cl3O3/c18-9-1-3-12-14(5-9)13(16(20)8-15(12)19)4-2-11-6-10(21)7-17(22)23-11/h1,3,5,8,10-11,21H,2,4,6-7H2/t10-,11?/m1/s1	FBQKLQQRNHLVNX-NFJWQWPMSA-N	50014955	4-Hydroxy-6-[2-(2,4,7-trichloro-naphthalen-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL350272	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 32							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014955	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014955&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44377995	103926829		CHEMBL350272				ZINC27863752	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022088	Cc1cc(Cl)c2ccc(Cl)cc2c1CCC1C[C@@H](O)CC(=O)O1	InChI=1S/C18H18Cl2O3/c1-10-6-17(20)15-4-2-11(19)7-16(15)14(10)5-3-13-8-12(21)9-18(22)23-13/h2,4,6-7,12-13,21H,3,5,8-9H2,1H3/t12-,13?/m1/s1	DDRAMGUROMYXMD-PZORYLMUSA-N	50014956	6-[2-(4,7-Dichloro-2-methyl-naphthalen-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL444604	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 60							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014956	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014956&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44378368	103926830		CHEMBL444604				ZINC27876026	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022089	Cc1ccc2c(C)cc(C)c(CCC3C[C@@H](O)CC(=O)O3)c2c1	InChI=1S/C20H24O3/c1-12-4-6-17-13(2)9-14(3)18(19(17)8-12)7-5-16-10-15(21)11-20(22)23-16/h4,6,8-9,15-16,21H,5,7,10-11H2,1-3H3/t15-,16?/m1/s1	IPXWDPHSKPNCLL-AAFJCEBUSA-N	50014957	4-Hydroxy-6-[2-(2,4,7-trimethyl-naphthalen-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL163734	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 360							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014957&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44378354	103926831		CHEMBL163734				ZINC27872959	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50022090	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cccc2cccc(Br)c12	InChI=1S/C17H15BrO3/c18-15-6-2-5-11-3-1-4-12(17(11)15)7-8-14-9-13(19)10-16(20)21-14/h1-8,13-14,19H,9-10H2/b8-7+/t13-,14-/m1/s1	DXIFCCAKJPUXII-GODNBWANSA-N	50014958	6-[2-(8-Bromo-naphthalen-1-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368310	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4120.0							ChEMBL	10.1021/jm00164a047	10.7270/Q2JQ1006	2299642			Prugh, JD; Alberts, AW; Deana, AA; Gilfillian, JL; Huff, JW; Smith, RL; Wiggins, JM	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014958	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014958&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73351422	103926832		CHEMBL2368310				ZINC27863738	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030061	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccc(Cl)cc1Cl	InChI=1S/C13H12Cl2O3/c14-9-3-1-8(12(15)5-9)2-4-11-6-10(16)7-13(17)18-11/h1-5,10-11,16H,6-7H2/b4-2+/t10-,11-/m1/s1	BGASINALMIKBMK-JTNORFRNSA-N	50026112	6-[2-(2,4-Dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368928	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 22000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026112&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			22822816	103935846		CHEMBL2368928				ZINC29409500	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030062	O[C@@H]1C[C@@H](CCc2c(Cl)cc(Cl)cc2OCc2ccccc2)OC(=O)C1	InChI=1S/C20H20Cl2O4/c21-14-8-18(22)17(7-6-16-10-15(23)11-20(24)26-16)19(9-14)25-12-13-4-2-1-3-5-13/h1-5,8-9,15-16,23H,6-7,10-12H2/t15-,16-/m1/s1	GMFRNTNFNHPQRE-HZPDHXFCSA-N	50405308	CHEMBL2115421	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5200							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405308&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13186026	163354332		CHEMBL2115421				ZINC29410867	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030063	O[C@@H]1C[C@@H](CCCc2c(Cl)cc(Cl)cc2COc2ccc(F)cc2)OC(=O)C1	InChI=1S/C21H21Cl2FO4/c22-14-8-13(12-27-17-6-4-15(24)5-7-17)19(20(23)9-14)3-1-2-18-10-16(25)11-21(26)28-18/h4-9,16,18,25H,1-3,10-12H2/t16-,18-/m1/s1	LWSQFTPUGSICLX-SJLPKXTDSA-N	50405307	CHEMBL2115420	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 170							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405307&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			71451000	163354331		CHEMBL2115420				ZINC95555868	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030064	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccccc1-c1ccccc1	InChI=1S/C19H18O3/c20-16-12-17(22-19(21)13-16)11-10-15-8-4-5-9-18(15)14-6-2-1-3-7-14/h1-11,16-17,20H,12-13H2/b11-10+/t16-,17-/m1/s1	YBRPATLKZYVIDP-XXRWXEQKSA-N	50024976	6-(2-Biphenyl-2-yl-vinyl)-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368911	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024976&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345350	103934946		CHEMBL2368911				ZINC29409116	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030065	O[C@@H]1C[C@@H](CCc2c(Cl)cc(Cl)cc2OCc2ccc(F)cc2)OC(=O)C1	InChI=1S/C20H19Cl2FO4/c21-13-7-18(22)17(6-5-16-9-15(24)10-20(25)27-16)19(8-13)26-11-12-1-3-14(23)4-2-12/h1-4,7-8,15-16,24H,5-6,9-11H2/t15-,16-/m1/s1	YOFPIUPACOQONI-HZPDHXFCSA-N	50405306	CHEMBL2114971	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 76							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405306&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13186038	163354330		CHEMBL2114971				ZINC29409173	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030066	O[C@@H]1C[C@@H](CCc2c(Cl)cc(Cl)cc2COc2ccccc2)OC(=O)C1	InChI=1S/C20H20Cl2O4/c21-14-8-13(12-25-16-4-2-1-3-5-16)18(19(22)9-14)7-6-17-10-15(23)11-20(24)26-17/h1-5,8-9,15,17,23H,6-7,10-12H2/t15-,17-/m1/s1	XPZIXVLKBLQPGX-NVXWUHKLSA-N	50405305	CHEMBL2114972	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 390							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405305&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13553219	163354329		CHEMBL2114972				ZINC95542503	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030067	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1ccc(F)cc1	InChI=1S/C19H15Cl2FO3/c20-12-7-17(11-1-3-13(22)4-2-11)16(18(21)8-12)6-5-15-9-14(23)10-19(24)25-15/h1-8,14-15,23H,9-10H2/b6-5+/t14-,15-/m1/s1	VMMVXGKAALDTIC-XEVLESSRSA-N	50024972	(+) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::(-) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368970	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 260							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024972&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			12802879	103934942		CHEMBL2368970				ZINC29480073	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030068	Cc1cc(C)cc(c1)-c1cc(C)cc(C)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C23H26O3/c1-14-7-15(2)10-18(9-14)22-11-16(3)8-17(4)21(22)6-5-20-12-19(24)13-23(25)26-20/h5-11,19-20,24H,12-13H2,1-4H3/b6-5+/t19-,20-/m1/s1	KNMFROHCOSXVOB-BGEOSOQGSA-N	50024974	4-Hydroxy-6-[2-(3,5,3'',5''-tetramethyl-biphenyl-2-yl)-vinyl]-tetrahydro-pyran-2-one::CHEMBL2368982	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024974	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024974&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352930	103934944		CHEMBL2368982				ZINC29482126	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030069	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1ccccc1	InChI=1S/C19H16Cl2O3/c20-13-8-17(12-4-2-1-3-5-12)16(18(21)9-13)7-6-15-10-14(22)11-19(23)24-15/h1-9,14-15,22H,10-11H2/b7-6+/t14-,15-/m1/s1	YUDDKXRBCZPNFK-WLBISTCBSA-N	50024973	6-[2-(3,5-Dichloro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368975	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 80							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024973	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024973&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354434	103934943		CHEMBL2368975				ZINC29480419	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030071	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccccc1-c1ccccc1	InChI=1S/C19H18O3/c20-16-12-17(22-19(21)13-16)11-10-15-8-4-5-9-18(15)14-6-2-1-3-7-14/h1-11,16-17,20H,12-13H2/b11-10+/t16-,17-/m1/s1	YBRPATLKZYVIDP-XXRWXEQKSA-N	50024976	6-(2-Biphenyl-2-yl-vinyl)-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368911	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3000							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024976&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345350	103934946		CHEMBL2368911				ZINC29409116	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030486	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C[C@@H]2C=C[C@H](C)[C@H](CCC(=O)C[C@@H](O)CC(O)=O)C12	InChI=1S/C24H38O6/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28/h6-7,14-17,19-21,23,26H,5,8-13H2,1-4H3,(H,27,28)/t14-,15-,16-,17-,19+,20-,21-,23?/m0/s1	OOKAZRDERJMRCJ-KOUAFAAESA-N	50020287	7-[2,6-Dimethyl-8-(2-methyl-butyryloxy)-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl]-3-hydroxy-5-oxo-heptanoic acid::7-[2,6-Dimethyl-8-(2-methyl-butyryloxy)-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl]-3-hydroxy-5-oxo-heptanoic acid(5-ketodihydromevinolin)::CHEMBL293944	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1							ChEMBL	10.1021/jm00121a036	10.7270/Q24T6HB3	2909732			Heathcock, CH; Davis, BR; Hadley, CR	University of California	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020287&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44298287	103931201		CHEMBL293944		3013	C03834	ZINC29551902	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030487	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CCC(O)C[C@@H](O)CC(O)=O)C12	InChI=1S/C23H36O6/c1-4-14(2)23(28)29-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-17(24)12-18(25)13-21(26)27/h6,8-9,14-15,17-20,22,24-25H,4-5,7,10-13H2,1-3H3,(H,26,27)/t14-,15-,17?,18+,19-,20-,22?/m0/s1	BOZILQFLQYBIIY-SSWMONTKSA-N	50020288	3,5-Dihydroxy-7-[6-hydroxy-2-methyl-8-(2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-heptanoic acid::CHEMBL58289	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1021/jm00121a036	10.7270/Q24T6HB3	2909732			Heathcock, CH; Davis, BR; Hadley, CR	University of California	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020288&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44303221	103931202		CHEMBL58289			C03834	ZINC29571159	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030488	OC(CCc1ccccc1)CC(O)CC(O)=O	InChI=1S/C13H18O4/c14-11(8-12(15)9-13(16)17)7-6-10-4-2-1-3-5-10/h1-5,11-12,14-15H,6-9H2,(H,16,17)	RHVDBYDDYIUVKS-UHFFFAOYSA-N	50020289	3,5-Dihydroxy-7-phenyl-heptanoic acid::CHEMBL59411	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 600000							ChEMBL	10.1021/jm00121a036	10.7270/Q24T6HB3	2909732			Heathcock, CH; Davis, BR; Hadley, CR	University of California	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020289&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			20293721	103931203		CHEMBL59411			C03834	ZINC29571395	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030489	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C[C@@H]2C=C[C@H](C)[C@H](CCC(O)C[C@@H](O)CC(O)=O)C12	InChI=1S/C24H40O6/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28/h6-7,14-21,23,25-26H,5,8-13H2,1-4H3,(H,27,28)/t14-,15-,16-,17-,18?,19+,20-,21-,23?/m0/s1	ROBLJKDXALYRTO-BBLPIHAXSA-N	50020290	7-[2,6-Dimethyl-8-(2-methyl-butyryloxy)-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl]-3,5-dihydroxy-heptanoic acid::CHEMBL59166	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.6							ChEMBL	10.1021/jm00121a036	10.7270/Q24T6HB3	2909732			Heathcock, CH; Davis, BR; Hadley, CR	University of California	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020290&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44303222	103931204		CHEMBL59166			C03834	ZINC29571378	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030490	O[C@@H](CC(O)=O)CC(=O)CCc1ccccc1	InChI=1S/C13H16O4/c14-11(8-12(15)9-13(16)17)7-6-10-4-2-1-3-5-10/h1-5,12,15H,6-9H2,(H,16,17)/t12-/m1/s1	AOBNEADIHQEJLV-GFCCVEGCSA-N	50020291	3-Hydroxy-5-oxo-7-phenyl-heptanoic acid::CHEMBL60053	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.3							ChEMBL	10.1021/jm00121a036	10.7270/Q24T6HB3	2909732			Heathcock, CH; Davis, BR; Hadley, CR	University of California	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020291&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44303431	103931205		CHEMBL60053		3020	C03834	ZINC26157359	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030491	CC[C@H](C)C(=O)OCc1ccccc1CCC(=O)C[C@@H](O)CC(O)=O	InChI=1S/C19H26O6/c1-3-13(2)19(24)25-12-15-7-5-4-6-14(15)8-9-16(20)10-17(21)11-18(22)23/h4-7,13,17,21H,3,8-12H2,1-2H3,(H,22,23)/t13-,17+/m0/s1	GQDBBROKVSIBNZ-SUMWQHHRSA-N	50020292	3-Hydroxy-7-[2-(2-methyl-butyryloxymethyl)-phenyl]-5-oxo-heptanoic acid::CHEMBL434604	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 320000							ChEMBL	10.1021/jm00121a036	10.7270/Q24T6HB3	2909732			Heathcock, CH; Davis, BR; Hadley, CR	University of California	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020292&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44303177	103931206		CHEMBL434604			C03834	ZINC26165136	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030492	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CCC(=O)C[C@@H](O)CC(O)=O)C12	InChI=1S/C23H34O6/c1-4-14(2)23(28)29-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-17(24)12-18(25)13-21(26)27/h6,8-9,14-15,18-20,22,25H,4-5,7,10-13H2,1-3H3,(H,26,27)/t14-,15-,18+,19-,20-,22?/m0/s1	ZXAJNDWFQLRHQS-ADNHDOAISA-N	50020293	3-Hydroxy-7-[6-hydroxy-2-methyl-8-(2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-5-oxo-heptanoic acid::CHEMBL61702	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 32							ChEMBL	10.1021/jm00121a036	10.7270/Q24T6HB3	2909732			Heathcock, CH; Davis, BR; Hadley, CR	University of California	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50020293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50020293&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44303231	103931207		CHEMBL61702			C03834	ZINC26153302	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50029775	O[C@@H]1C[C@H](OC(=O)C1)C=C1c2ccccc2-c2ccccc12	InChI=1S/C19H16O3/c20-12-9-13(22-19(21)10-12)11-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,11-13,20H,9-10H2/t12-,13+/m1/s1	CQRTWQUVDHQCCK-OLZOCXBDSA-N	50024971	6-Fluoren-9-ylidenemethyl-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2367922	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 890							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024971	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024971&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73351395	103934941		CHEMBL2367922				ZINC27182644	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50029776	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccc(Cl)cc1Cl	InChI=1S/C13H12Cl2O3/c14-9-3-1-8(12(15)5-9)2-4-11-6-10(16)7-13(17)18-11/h1-5,10-11,16H,6-7H2/b4-2+/t10-,11-/m1/s1	BGASINALMIKBMK-JTNORFRNSA-N	50026112	6-[2-(2,4-Dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368928	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 22000							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026112&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			22822816	103935846		CHEMBL2368928				ZINC29409500	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032422	COc1ccc(cc1)-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-3-8-18(14-4-6-16(23-2)7-5-14)20(13)10-9-17-11-15(21)12-19(22)24-17/h3-8,15,17,21H,9-12H2,1-2H3/t15-,17-/m1/s1	ZQIWXGRLHMBHIH-NVXWUHKLSA-N	50014665	4-Hydroxy-6-{2-[2-(4-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL319905	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014665&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785446	103926560		CHEMBL319905				ZINC26835340	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032423	Cc1ccc(-c2ccc(F)cc2)n1-c1ccccc1[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H20FNO3/c1-14-6-11-19(15-7-9-16(23)10-8-15)24(14)20-5-3-2-4-18(20)21-12-17(25)13-22(26)27-21/h2-11,17,21,25H,12-13H2,1H3/t17-,21+/m1/s1	KHSMWSDWTINZRY-UTKZUKDTSA-N	50014685	6-{2-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL317403	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014685&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335521	103926580		CHEMBL317403				ZINC26831212	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032424	CC(C)c1ccc(-c2ccc(F)cc2F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H23F2NO3/c1-12(2)18-5-6-19(16-4-3-13(21)9-17(16)22)23(18)8-7-15-10-14(24)11-20(25)26-15/h3-6,9,12,14-15,24H,7-8,10-11H2,1-2H3/t14-,15-/m1/s1	FZPCAVZWUCPNEC-HUUCEWRRSA-N	50014680	6-{2-[2-(2,4-Difluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL430472	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1600							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014680&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335523	103926575		CHEMBL430472				ZINC26835346	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032425	COc1ccccc1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H27NO4/c1-14(2)18-8-9-19(17-6-4-5-7-20(17)25-3)22(18)11-10-16-12-15(23)13-21(24)26-16/h4-9,14-16,23H,10-13H2,1-3H3/t15-,16-/m1/s1	NYSJCZLVRXRHGX-HZPDHXFCSA-N	50014693	4-Hydroxy-6-{2-[2-isopropyl-5-(2-methoxy-phenyl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104031	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2200							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014693&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335522	103926588		CHEMBL104031				ZINC26835344	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032428	CC(C)c1ccc(-c2ccccc2F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-7-8-19(16-5-3-4-6-17(16)21)22(18)10-9-15-11-14(23)12-20(24)25-15/h3-8,13-15,23H,9-12H2,1-2H3/t14-,15-/m1/s1	KSMFJPWAYPAKQZ-HUUCEWRRSA-N	50014684	6-{2-[2-(2-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104595	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1585							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014684&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335602	103926579		CHEMBL104595				ZINC26834201	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032431	CC(C)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-7-8-19(14-3-5-15(21)6-4-14)22(18)10-9-17-11-16(23)12-20(24)25-17/h3-8,13,16-17,23H,9-12H2,1-2H3/t16-,17-/m1/s1	ZYSGPNCFTPUHGN-IAGOWNOFSA-N	50011034	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104044	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 398							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011034	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011034&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785438	103923729		CHEMBL104044				ZINC13861016	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032433	CC(C)c1ccc(-c2ccc(F)cc2)n1CC(C)[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H26FNO3/c1-13(2)18-8-9-19(15-4-6-16(22)7-5-15)23(18)12-14(3)20-10-17(24)11-21(25)26-20/h4-9,13-14,17,20,24H,10-12H2,1-3H3/t14?,17-,20+/m1/s1	OMUIQGPGHFNSLA-SBCCGAISSA-N	50014691	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-1-methyl-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL318596	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014691&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335922	103926586		CHEMBL318596				ZINC26835130	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032438	COc1ccc2ccccc2c1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H29NO4/c1-16(2)21-9-10-22(26(21)13-12-19-14-18(27)15-24(28)30-19)25-20-7-5-4-6-17(20)8-11-23(25)29-3/h4-11,16,18-19,27H,12-15H2,1-3H3/t18-,19-/m1/s1	WFMHEDHHCWBSIB-RTBURBONSA-N	50014699	4-Hydroxy-6-{2-[2-isopropyl-5-(2-methoxy-naphthalen-1-yl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104639	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25119							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014699&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335605	103926594		CHEMBL104639				ZINC26834871	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032442	O[C@@H]1C[C@@H](CCn2c(ccc2-c2ccc(F)cc2)C2CCCCC2)OC(=O)C1	InChI=1S/C23H28FNO3/c24-18-8-6-17(7-9-18)22-11-10-21(16-4-2-1-3-5-16)25(22)13-12-20-14-19(26)15-23(27)28-20/h6-11,16,19-20,26H,1-5,12-15H2/t19-,20-/m1/s1	CQLCSKXQNGSOLY-WOJBJXKFSA-N	50014681	6-{2-[2-Cyclohexyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322367	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014681&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335592	103926576		CHEMBL322367				ZINC26836770	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032447	Cc1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H20FNO3/c1-12-2-7-17(13-3-5-14(19)6-4-13)20(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,21H,8-11H2,1H3/t15-,16-/m1/s1	QNKLRMPQOSICFR-HZPDHXFCSA-N	50014683	CHEMBL104660::i6-{2-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 501							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014683&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18606835	103926578		CHEMBL104660				ZINC26838114	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032448	Cc1ccc(-c2ccc(cc2)-c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C24H25NO3/c1-17-7-12-23(25(17)14-13-22-15-21(26)16-24(27)28-22)20-10-8-19(9-11-20)18-5-3-2-4-6-18/h2-12,21-22,26H,13-16H2,1H3/t21-,22-/m1/s1	NSUYYCLWHSMXLG-FGZHOGPDSA-N	50014675	6-[2-(2-Biphenyl-4-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL107995	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25119							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014675&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785450	103926570		CHEMBL107995				ZINC26839318	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032449	Cc1ccc(-c2cccc3ccccc23)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H23NO3/c1-15-9-10-21(20-8-4-6-16-5-2-3-7-19(16)20)23(15)12-11-18-13-17(24)14-22(25)26-18/h2-10,17-18,24H,11-14H2,1H3/t17-,18-/m1/s1	MVCRJKMSDFMOAD-QZTJIDSGSA-N	50014690	4-Hydroxy-6-[2-(2-methyl-5-naphthalen-1-yl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL320352	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014690&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785452	103926585		CHEMBL320352				ZINC26839364	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032451	CC(C)c1ccc(-c2cccc(F)c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-6-7-19(14-4-3-5-15(21)10-14)22(18)9-8-17-11-16(23)12-20(24)25-17/h3-7,10,13,16-17,23H,8-9,11-12H2,1-2H3/t16-,17-/m1/s1	AHVDPZLQANCRDN-IAGOWNOFSA-N	50014671	6-{2-[2-(3-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104295	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1300							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014671&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335590	103926566		CHEMBL104295				ZINC26836762	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032455	COc1ccccc1-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-7-8-17(16-5-3-4-6-18(16)23-2)20(13)10-9-15-11-14(21)12-19(22)24-15/h3-8,14-15,21H,9-12H2,1-2H3/t14-,15-/m1/s1	WQWAGILDBLSBQH-HUUCEWRRSA-N	50014694	4-Hydroxy-6-{2-[2-(2-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL317854	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014694&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785444	103926589		CHEMBL317854				ZINC26835406	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032457	Cc1ccc(C2CCCCC2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H27NO3/c1-13-7-8-17(14-5-3-2-4-6-14)19(13)10-9-16-11-15(20)12-18(21)22-16/h7-8,14-16,20H,2-6,9-12H2,1H3/t15-,16-/m1/s1	PLAOFIRLJLTRNR-HZPDHXFCSA-N	50014701	6-[2-(2-Cyclohexyl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL107753	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2200							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014701&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785448	103926596		CHEMBL107753				ZINC26839065	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032458	Cc1ccc(C(c2ccccc2)c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H27NO3/c1-18-12-13-23(26(18)15-14-22-16-21(27)17-24(28)29-22)25(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-13,21-22,25,27H,14-17H2,1H3/t21-,22-/m1/s1	ZYOUITAWBXBZCC-FGZHOGPDSA-N	50014689	6-[2-(2-Benzhydryl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104703	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8900							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014689&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785458	103926584		CHEMBL104703				ZINC26837186	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032462	COc1cccc(c1)-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-6-7-18(14-4-3-5-16(10-14)23-2)20(13)9-8-17-11-15(21)12-19(22)24-17/h3-7,10,15,17,21H,8-9,11-12H2,1-2H3/t15-,17-/m1/s1	ZUJYBBIDWOTFNW-NVXWUHKLSA-N	50014678	CHEMBL104866::i4-Hydroxy-6-{2-[2-(3-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2512							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014678&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335855	103926573		CHEMBL104866				ZINC26835999	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032467	CC(C)c1ccc(-c2ccccc2Cl)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24ClNO3/c1-13(2)18-7-8-19(16-5-3-4-6-17(16)21)22(18)10-9-15-11-14(23)12-20(24)25-15/h3-8,13-15,23H,9-12H2,1-2H3/t14-,15-/m1/s1	HKCTYZKXOAMQGS-HUUCEWRRSA-N	50014670	6-{2-[2-(2-Chloro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322724	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014670&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335617	103926565		CHEMBL322724				ZINC26839399	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032470	Cc1ccc(-c2ccccc2O)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-6-7-16(15-4-2-3-5-17(15)21)19(12)9-8-14-10-13(20)11-18(22)23-14/h2-7,13-14,20-21H,8-11H2,1H3/t13-,14-/m1/s1	HRJNORMWLOECJJ-ZIAGYGMSSA-N	50014673	4-Hydroxy-6-{2-[2-(2-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104405	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014673&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335883	103926568		CHEMBL104405				ZINC26835403	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032473	Cc1ccc(-c2ccc(F)cc2)n1-c1cccc(c1)[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H20FNO3/c1-14-5-10-20(15-6-8-17(23)9-7-15)24(14)18-4-2-3-16(11-18)21-12-19(25)13-22(26)27-21/h2-11,19,21,25H,12-13H2,1H3/t19-,21+/m1/s1	NRTHZCAQMYJGGO-CTNGQTDRSA-N	50014692	6-{3-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL105511	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25100							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014692&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335495	103926587		CHEMBL105511				ZINC26836203	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032474	CC(C)c1ccc(-c2cc(C)ccc2C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H29NO3/c1-14(2)20-7-8-21(19-11-15(3)5-6-16(19)4)23(20)10-9-18-12-17(24)13-22(25)26-18/h5-8,11,14,17-18,24H,9-10,12-13H2,1-4H3/t17-,18-/m1/s1	WEXBLGVLOVZWCC-QZTJIDSGSA-N	50014687	6-{2-[2-(2,5-Dimethyl-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL280437	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014687&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335612	103926582		CHEMBL280437				ZINC26830938	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032476	COc1cccc(OC)c1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H29NO5/c1-14(2)17-8-9-18(22-19(26-3)6-5-7-20(22)27-4)23(17)11-10-16-12-15(24)13-21(25)28-16/h5-9,14-16,24H,10-13H2,1-4H3/t15-,16-/m1/s1	VGXGUJPBOIYJRO-HZPDHXFCSA-N	50014672	6-{2-[2-(2,6-Dimethoxy-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL323256	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 19953							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014672&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335570	103926567		CHEMBL323256				ZINC26849023	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032478	O[C@@H]1C[C@@H](CCn2c(ccc2-c2ccc(F)cc2)C2CC2)OC(=O)C1	InChI=1S/C20H22FNO3/c21-15-5-3-14(4-6-15)19-8-7-18(13-1-2-13)22(19)10-9-17-11-16(23)12-20(24)25-17/h3-8,13,16-17,23H,1-2,9-12H2/t16-,17-/m1/s1	YXISEZLIKDLBHD-IAGOWNOFSA-N	50014695	6-{2-[2-Cyclopropyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL106062	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2200							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014695&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335566	103926590		CHEMBL106062				ZINC26832445	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032479	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 26							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032482	Cc1ccc(-c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO3/c1-13-7-8-17(14-5-3-2-4-6-14)19(13)10-9-16-11-15(20)12-18(21)22-16/h2-8,15-16,20H,9-12H2,1H3/t15-,16-/m1/s1	GRYRYCIEQRBDRS-HZPDHXFCSA-N	50014676	4-Hydroxy-6-[2-(2-methyl-5-phenyl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL106720	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12589							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014676&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785440	103926571		CHEMBL106720				ZINC26836779	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032485	CCC(CC)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H28FNO3/c1-3-15(4-2)20-9-10-21(16-5-7-17(23)8-6-16)24(20)12-11-19-13-18(25)14-22(26)27-19/h5-10,15,18-19,25H,3-4,11-14H2,1-2H3/t18-,19-/m1/s1	OOANXJFGKWCWIB-RTBURBONSA-N	50014697	6-{2-[2-(1-Ethyl-propyl)-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL321930	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014697&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335567	103926592		CHEMBL321930				ZINC26832449	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032657	Cn1nnnc1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H22F2N4O4/c1-29-23(26-27-28-29)20(11-10-18(30)12-19(31)13-21(32)33)22(14-2-6-16(24)7-3-14)15-4-8-17(25)9-5-15/h2-11,18-19,30-31H,12-13H2,1H3,(H,32,33)/p-1/b11-10+/t18-,19-/m1/s1	HPFIYXJJZZWEPC-MMKWGKFASA-M	50014345	CHEMBL11804::Sodium; (E)-(3R,5S)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>300000							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014345&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18647991	103926367		CHEMBL11804			C03834	ZINC03782329	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032659	CC(C)(C)n1nnc(n1)C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C26H28F2N4O4/c1-26(2,3)32-30-25(29-31-32)22(13-12-20(33)14-21(34)15-23(35)36)24(16-4-8-18(27)9-5-16)17-6-10-19(28)11-7-17/h4-13,20-21,33-34H,14-15H2,1-3H3,(H,35,36)/p-1/b13-12+/t20-,21-/m1/s1	VTYNAOFVUPXGON-DDVDASKDSA-M	50014351	CHEMBL323373::Sodium; 8-(2-tert-butyl-2H-tetrazol-5-yl)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3700							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014351&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928894	103926373		CHEMBL323373			C03834	ZINC26820011	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50631137	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-BXMDZJJMSA-N	34168	LOVASTATIN::MLS000069585::SMR000058779::US9115116, lovastatin::US9353061, Lovastatina::cid_53232	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 32							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34168&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	803	1CQP,7KC6	53232	252616855	40303		DB00227	2739	C07074	ZINC03812841	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032521	Cc1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C25H22FNO3/c1-16-22(12-11-21-13-20(28)14-25(29)30-21)23(17-7-9-19(26)10-8-17)15-24(27-16)18-5-3-2-4-6-18/h2-12,15,20-21,28H,13-14H2,1H3/b12-11+/t20-,21-/m1/s1	UHKYOMOXQPXMQY-LKWCPCFXSA-N	50406102	CHEMBL2111268	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 38							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406102&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14460204	163355126		CHEMBL2111268				ZINC27653721	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032522	Cc1nc(C)c(\C=C/[C@@H]2C[C@@H](O)CC(=O)O2)c(n1)-c1ccc(Cl)cc1	InChI=1S/C19H19ClN2O3/c1-11-17(8-7-16-9-15(23)10-18(24)25-16)19(22-12(2)21-11)13-3-5-14(20)6-4-13/h3-8,15-16,23H,9-10H2,1-2H3/b8-7-/t15-,16-/m1/s1	TZJHSQWXRDXDCN-ZJBFNYKTSA-N	50406104	CHEMBL2111237	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406104	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406104&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			70693572	163355128		CHEMBL2111237				ZINC38148819	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032525	Cc1nc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(n1)-c1ccc(Cl)cc1	InChI=1S/C19H19ClN2O3/c1-11-17(8-7-16-9-15(23)10-18(24)25-16)19(22-12(2)21-11)13-3-5-14(20)6-4-13/h3-8,15-16,23H,9-10H2,1-2H3/b8-7+/t15-,16-/m1/s1	TZJHSQWXRDXDCN-XLBHYRNJSA-N	50406105	CHEMBL2111270	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 600							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406105&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			70695696	163355129		CHEMBL2111270				ZINC27655486	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032526	Cc1cc(-c2ccc(F)cc2)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(C)n1	InChI=1S/C20H20FNO3/c1-12-9-19(14-3-5-15(21)6-4-14)18(13(2)22-12)8-7-17-10-16(23)11-20(24)25-17/h3-9,16-17,23H,10-11H2,1-2H3/b8-7+/t16-,17-/m1/s1	ANOPSFFNQJWFSF-NXVGNOFTSA-N	50406106	CHEMBL2111271	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 260							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406106&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14460200	163355130		CHEMBL2111271				ZINC27655492	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032527	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-BXMDZJJMSA-N	34168	LOVASTATIN::MLS000069585::SMR000058779::US9115116, lovastatin::US9353061, Lovastatina::cid_53232	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8							ChEMBL	10.1021/jm00163a010	10.7270/Q22N5177	2296036			Beck, G; Kesseler, K; Baader, E; Bartmann, W; Bergmann, A; Granzer, E; Jendralla, H; von Kerekjarto, B; Krause, R; Paulus, E	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34168&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	803	1CQP,7KC6	53232	252616855	40303		DB00227	2739	C07074	ZINC03812841	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032656	CC(C)n1nnnc1C(C=C=C[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C26H26F2N4O4/c1-16(2)32-26(29-30-31-32)23(5-3-4-21(33)14-22(34)15-24(35)36)25(17-6-10-19(27)11-7-17)18-8-12-20(28)13-9-18/h4-13,16,21-22,33-34H,14-15H2,1-2H3,(H,35,36)/p-1/t3?,21?,22-/m1/s1	XJYKQLOZROGRRD-OTUYVNSBSA-M	50014367	CHEMBL103792::Sodium; 10,10-bis-(4-fluoro-phenyl)-3,5-dihydroxy-9-(1-isopropyl-1H-tetrazol-5-yl)-deca-6,7,9-trienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 130000							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014367	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014367&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928908	103926389		CHEMBL103792			C03834	ZINC26818262	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032658	CC(C)(C)n1nnc(n1)C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C26H28F2N4O4/c1-26(2,3)32-30-25(29-31-32)22(13-12-20(33)14-21(34)15-23(35)36)24(16-4-8-18(27)9-5-16)17-6-10-19(28)11-7-17/h4-13,20-21,33-34H,14-15H2,1-3H3,(H,35,36)/p-1/b13-12+/t20-,21-/m1/s1	VTYNAOFVUPXGON-DDVDASKDSA-M	50014351	CHEMBL323373::Sodium; 8-(2-tert-butyl-2H-tetrazol-5-yl)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3700							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014351&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928894	103926373		CHEMBL323373			C03834	ZINC26820011	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032660	Cn1nnnc1C(C=C=C[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C24H22F2N4O4/c1-30-24(27-28-29-30)21(4-2-3-19(31)13-20(32)14-22(33)34)23(15-5-9-17(25)10-6-15)16-7-11-18(26)12-8-16/h3-12,19-20,31-32H,13-14H2,1H3,(H,33,34)/p-1/t2?,19-,20-/m1/s1	SOQGKEBESUFIIN-KRMGUPMMSA-M	50421879	CHEMBL2304072	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5700							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50421879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50421879&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91900170	164150754		CHEMBL2304072			C03834	ZINC36242995	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50033902	CCC(C)(C)C(=O)O[C@H]1C[C@](C)(CSc2ccccc2)O[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C31H46O6S/c1-6-30(3,4)29(34)36-26-18-31(5,19-38-23-10-8-7-9-11-23)37-25-15-12-20(2)24(28(25)26)14-13-22-16-21(32)17-27(33)35-22/h7-11,20-22,24-26,28,32H,6,12-19H2,1-5H3/t20-,21+,22?,24-,25+,26-,28-,31?/m0/s1	JVCPPJZJTBTKEY-PRFHOCJISA-N	50406550	CHEMBL2114188::CHEMBL3349570	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406550&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718445	163355574		CHEMBL3349570CHEMBL2114188				ZINC26504030	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50033903	CCC(C)(C)C(=O)O[C@H]1C[C@@](C)(CSc2ccccc2)O[C@@H]2CC[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C31H46O6S/c1-6-30(3,4)29(34)36-26-18-31(5,19-38-23-10-8-7-9-11-23)37-25-15-12-20(2)24(28(25)26)14-13-22-16-21(32)17-27(33)35-22/h7-11,20-22,24-26,28,32H,6,12-19H2,1-5H3/t20-,21+,22?,24-,25+,26-,28+,31?/m0/s1	JVCPPJZJTBTKEY-AUSQDNQYSA-N	50406549	CHEMBL2115196::CHEMBL3349562	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.6							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406549&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718440	163355573		CHEMBL3349562CHEMBL2115196				ZINC95556568	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50033240	[Na+].CC(C)c1nn(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1cnccn1	InChI=1S/C23H25FN4O4.Na/c1-14(2)22-19(8-7-17(29)11-18(30)12-21(31)32)23(15-3-5-16(24)6-4-15)28(27-22)20-13-25-9-10-26-20;/h3-10,13-14,17-18,29-30H,11-12H2,1-2H3,(H,31,32);/q;+1/p-1/b8-7+;/t17-,18-;/m1./s1	TVZACJNNVHKXCP-LFXPJKTASA-M	50006407	CHEMBL2367472::Sodium; 7-[5-(4-fluoro-phenyl)-3-isopropyl-1-pyrazin-2-yl-1H-pyrazol-4-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.6							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006407&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23695881	103919827		CHEMBL2367472				ZINC26182747	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50033242	Cn1nnnc1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H22F2N4O4/c1-29-23(26-27-28-29)20(11-10-18(30)12-19(31)13-21(32)33)22(14-2-6-16(24)7-3-14)15-4-8-17(25)9-5-15/h2-11,18-19,30-31H,12-13H2,1H3,(H,32,33)/p-1/b11-10+/t18-,19-/m1/s1	HPFIYXJJZZWEPC-MMKWGKFASA-M	50014345	CHEMBL11804::Sodium; (E)-(3R,5S)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014345&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18647991	103926367		CHEMBL11804			C03834	ZINC03782329	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50033243	[Na+].CC(C)c1nn(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1ccccc1	InChI=1S/C25H27FN2O4.Na/c1-16(2)24-22(13-12-20(29)14-21(30)15-23(31)32)25(17-8-10-18(26)11-9-17)28(27-24)19-6-4-3-5-7-19;/h3-13,16,20-21,29-30H,14-15H2,1-2H3,(H,31,32);/q;+1/p-1/b13-12+;/t20-,21-;/m1./s1	ABNXPCBQPDGROH-VRHXWEEISA-M	50006409	CHEMBL2367478::Sodium; 7-[5-(4-fluoro-phenyl)-3-isopropyl-1-phenyl-1H-pyrazol-4-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.2							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006409&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23695889	103919829		CHEMBL2367478				ZINC26190087	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50033244	[Na+].CC(C)c1nn(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1ccccn1	InChI=1S/C24H26FN3O4.Na/c1-15(2)23-20(11-10-18(29)13-19(30)14-22(31)32)24(16-6-8-17(25)9-7-16)28(27-23)21-5-3-4-12-26-21;/h3-12,15,18-19,29-30H,13-14H2,1-2H3,(H,31,32);/q;+1/p-1/b11-10+;/t18-,19-;/m1./s1	PIABXITYZIUXBZ-QKPRLWPNSA-M	50006410	CHEMBL2367477::Sodium; 7-[5-(4-fluoro-phenyl)-3-isopropyl-1-pyridin-2-yl-1H-pyrazol-4-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006410&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23695878	103919830		CHEMBL2367477				ZINC26183512	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50033245	OC(COc1c(Cl)cc(Cl)cc1C(c1ccc(F)cc1)c1ccc(F)cc1)C[C@@H](O)CC([O-])=O	InChI=1S/C25H22Cl2F2O5/c26-16-9-21(25(22(27)10-16)34-13-20(31)11-19(30)12-23(32)33)24(14-1-5-17(28)6-2-14)15-3-7-18(29)8-4-15/h1-10,19-20,24,30-31H,11-13H2,(H,32,33)/p-1/t19-,20?/m1/s1	VQWSITRBHPOQTC-FIWHBWSRSA-M	50007289	CHEMBL100721::Sodium; 6-{2-[bis-(4-fluoro-phenyl)-methyl]-4,6-dichloro-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 950							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007289&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928775	103920567		CHEMBL100721			C03834	ZINC26747375	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50033249	CCC(C)(C)C(=O)NC(C1CCCCC1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C27H43NO6/c1-6-27(4,5)26(33)28-24(19-10-8-7-9-11-19)22-13-17(2)12-18(3)25(22)34-16-21(30)14-20(29)15-23(31)32/h12-13,19-21,24,29-30H,6-11,14-16H2,1-5H3,(H,28,33)(H,31,32)/p-1/t20-,21?,24?/m1/s1	XAFSODPXPFYGDP-UZGSZPBKSA-M	50007284	CHEMBL101600::Sodium; 6-{2-[cyclohexyl-(2,2-dimethyl-butyrylamino)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 320							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007284&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928773	103920563		CHEMBL101600			C03834	ZINC26744177	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039061	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cccc2ccc3ccccc3c12	InChI=1S/C21H18O3/c22-17-12-18(24-20(23)13-17)11-10-16-6-3-5-15-9-8-14-4-1-2-7-19(14)21(15)16/h1-11,17-18,22H,12-13H2/b11-10+/t17-,18-/m1/s1	BRQUCHLWPZMOAV-NDZBKKTDSA-N	50026319	4-Hydroxy-6-(2-phenanthren-4-yl-vinyl)-tetrahydro-pyran-2-one::CHEMBL118592	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1900							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026319&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44345850	103936029		CHEMBL118592				ZINC27107050	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039062	O[C@@H]1C[C@@H](CCc2ccc(Cl)cc2Cl)OC(=O)C1	InChI=1S/C13H14Cl2O3/c14-9-3-1-8(12(15)5-9)2-4-11-6-10(16)7-13(17)18-11/h1,3,5,10-11,16H,2,4,6-7H2/t10-,11-/m1/s1	CEXNFLNQAGNWPV-GHMZBOCLSA-N	50026320	6-[2-(2,4-Dichloro-phenyl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL120354	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15200							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026320	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026320&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13186031	103936030		CHEMBL120354				ZINC06091932	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039063	O[C@@H]1CC(CCc2cccc3ccccc23)OC(=O)C1	InChI=1S/C17H18O3/c18-14-10-15(20-17(19)11-14)9-8-13-6-3-5-12-4-1-2-7-16(12)13/h1-7,14-15,18H,8-11H2/t14-,15?/m1/s1	APQYISHFWANGRJ-GICMACPYSA-N	50014952	4-Hydroxy-6-(2-naphthalen-1-yl-ethyl)-tetrahydro-pyran-2-one::CHEMBL118866	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 129000							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014952	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014952&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44345838	103926826		CHEMBL118866				ZINC27107527	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039064	C[C@@]1(O)C[C@@H](CCc2ccc(Cl)cc2Cl)OC(=O)C1	InChI=1S/C14H16Cl2O3/c1-14(18)7-11(19-13(17)8-14)5-3-9-2-4-10(15)6-12(9)16/h2,4,6,11,18H,3,5,7-8H2,1H3/t11-,14-/m1/s1	YHUAWSMWEWKJFW-BXUZGUMPSA-N	50026321	6-[2-(2,4-Dichloro-phenyl)-ethyl]-4-hydroxy-4-methyl-tetrahydro-pyran-2-one::CHEMBL332558	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 19800							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026321	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026321&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44345518	103936031		CHEMBL332558				ZINC27181682	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039065	C[C@@]1(O)C[C@H](OC(=O)C1)\C=C\c1ccc(Cl)cc1Cl	InChI=1S/C14H14Cl2O3/c1-14(18)7-11(19-13(17)8-14)5-3-9-2-4-10(15)6-12(9)16/h2-6,11,18H,7-8H2,1H3/b5-3+/t11-,14-/m1/s1	KVMVGKRXAFJMEV-UOLJMSNASA-N	50026322	6-[2-(2,4-Dichloro-phenyl)-vinyl]-4-hydroxy-4-methyl-tetrahydro-pyran-2-one::CHEMBL2367920	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20000							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026322	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026322&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73351394	103936032		CHEMBL2367920				ZINC27180704	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039066	O[C@@H]1C[C@@H](CC[C@@H]2CCC[C@@H]3CCCC[C@H]23)OC(=O)C1	InChI=1S/C17H28O3/c18-14-10-15(20-17(19)11-14)9-8-13-6-3-5-12-4-1-2-7-16(12)13/h12-16,18H,1-11H2/t12-,13-,14+,15+,16-/m0/s1	YDLCQOCHJQIQPB-RBZJEDDUSA-N	50026323	6-[2-(Decahydro-naphthalen-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL120403	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 107000							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026323&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44345564	103936033		CHEMBL120403				ZINC27109924	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039067	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039069	O[C@@H]1CC(CC[C@@H]2CC[C@H]3CCCC[C@@H]3C2)OC(=O)C1	InChI=1S/C17H28O3/c18-15-10-16(20-17(19)11-15)8-6-12-5-7-13-3-1-2-4-14(13)9-12/h12-16,18H,1-11H2/t12-,13+,14+,15+,16?/m0/s1	REOFYIFLGXWQNX-OWVXKZQJSA-N	50026325	6-[2-(Decahydro-naphthalen-2-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL120524	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 90000							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026325&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44345563	103936035		CHEMBL120524				ZINC27179798	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039070	O[C@@H]1C[C@H](OC(=O)C1)C=C1c2ccccc2C=Cc2ccccc12	InChI=1S/C21H18O3/c22-16-11-17(24-21(23)12-16)13-20-18-7-3-1-5-14(18)9-10-15-6-2-4-8-19(15)20/h1-10,13,16-17,22H,11-12H2/t16-,17+/m1/s1	VNEIWOVPLCNDAZ-SJORKVTESA-N	50026324	6-Dibenzo[a,d]cyclohepten-5-ylidenemethyl-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL118591	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1600							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026324	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026324&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44345849	103936034		CHEMBL118591				ZINC27107047	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036965	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19?,20-,21-,23?/m0/s1	RYMZZMVNJRMUDD-RJDSDMDFSA-N	50003240	2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::BDBM50024625::CHEMBL3349544	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 0.900000							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003240&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13298846	103917220		CHEMBL3349544CHEMBL309552				ZINC26504557	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036966	CC(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C26H40O5/c1-6-26(5,7-2)25(29)31-22-13-16(3)12-18-9-8-17(4)21(24(18)22)11-10-20-14-19(27)15-23(28)30-20/h8-9,12,16-17,19-22,24,27H,6-7,10-11,13-15H2,1-5H3/t16-,17-,19+,20?,21-,22-,24?/m0/s1	OKOKBYYKKPVXFH-BVKPCACGSA-N	50024627	2-Ethyl-2-methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL3349960	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.7							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024627&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718668	103934732		CHEMBL3349960CHEMBL167141				ZINC27895273	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036967	C[C@@H]1C[C@H](OC(C)=O)C2[C@@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C24H36O5/c1-4-5-6-22(26)29-21-12-15(2)11-17-8-7-16(3)20(24(17)21)10-9-19-13-18(25)14-23(27)28-19/h7-8,11,15-16,18-21,24-25H,4-6,9-10,12-14H2,1-3H3/t15-,16-,18+,19?,20-,21-,24?/m0/s1	DFJYFYDMJKZJIN-YXUFBLGQSA-N	50024626	CHEMBL3349957::Pentanoic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 269							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024626&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718665	103934731		CHEMBL3349957CHEMBL168768				ZINC27981075	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036968	CC[C@@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15+,16-,18+,19?,20-,21-,23?/m0/s1	PCZOHLXUXFIOCF-MPLNJFINSA-N	50024628	2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL3349951	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.2							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024628&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718659	103934733		CHEMBL3349951CHEMBL167159				ZINC27899846	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036969	CC(C)CC(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C24H36O5/c1-14(2)9-22(26)29-21-11-15(3)10-17-6-5-16(4)20(24(17)21)8-7-19-12-18(25)13-23(27)28-19/h5-6,10,14-16,18-21,24-25H,7-9,11-13H2,1-4H3/t15-,16-,18+,19?,20-,21-,24?/m0/s1	ACBUMLHZTSHRKJ-YXUFBLGQSA-N	50024629	3-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL3349949	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5.4							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024629&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718657	103934734		CHEMBL3349949CHEMBL352791				ZINC27981366	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036970	CC(CC(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12)C(F)(F)F	InChI=1S/C24H33F3O5/c1-13-8-16-5-4-14(2)19(7-6-18-11-17(28)12-22(30)31-18)23(16)20(9-13)32-21(29)10-15(3)24(25,26)27/h4-5,8,13-15,17-20,23,28H,6-7,9-12H2,1-3H3/t13-,14-,15?,17+,18?,19-,20-,23?/m0/s1	DDZBRJBYGLTADL-TZFBGDORSA-N	50024630	4,4,4-Trifluoro-3-methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL3349952	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.5							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024630&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718660	103934735		CHEMBL3349952CHEMBL352956				ZINC36243024	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036972	C[C@@H]1C[C@H](OC(=O)Oc2ccccc2)C2[C@@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C26H32O6/c1-16-12-18-9-8-17(2)22(11-10-21-14-19(27)15-24(28)30-21)25(18)23(13-16)32-26(29)31-20-6-4-3-5-7-20/h3-9,12,16-17,19,21-23,25,27H,10-11,13-15H2,1-2H3/t16-,17-,19+,21?,22-,23-,25?/m0/s1	VQBJRQBKKILJEP-WTHGXFPZSA-N	50024631	CHEMBL3349947::Carbonic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester phenyl ester: 1/4 C4H9Cl	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 83							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024631&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718655	103934736		CHEMBL3349947CHEMBL355889				ZINC27902069	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036973	C[C@@H]1C[C@H](OC(=O)c2ccc(F)cc2)C2[C@@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C26H31FO5/c1-15-11-18-4-3-16(2)22(10-9-21-13-20(28)14-24(29)31-21)25(18)23(12-15)32-26(30)17-5-7-19(27)8-6-17/h3-8,11,15-16,20-23,25,28H,9-10,12-14H2,1-2H3/t15-,16-,20+,21?,22-,23-,25?/m0/s1	STTLOPOWBJDUQC-YEDSVQHBSA-N	50024635	4-Fluoro-benzoic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL3349948	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 37							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024635&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718656	103934740		CHEMBL3349948CHEMBL352790				ZINC27981345	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036974	CCCCC(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C29H46O5/c1-4-5-6-7-8-9-10-11-27(31)34-26-17-20(2)16-22-13-12-21(3)25(29(22)26)15-14-24-18-23(30)19-28(32)33-24/h12-13,16,20-21,23-26,29-30H,4-11,14-15,17-19H2,1-3H3/t20-,21-,23+,24?,25-,26-,29?/m0/s1	PJPGFHPNQKOIFU-GZJDGNINSA-N	50024633	CHEMBL3349958::Decanoic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8.7							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024633&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718666	103934738		CHEMBL3349958CHEMBL168368				ZINC36243033	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036975	C[C@@H]1C[C@H](OC(=O)Cc2ccccc2)[C@@H]2[C@@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C27H34O5/c1-17-12-20-9-8-18(2)23(11-10-22-15-21(28)16-26(30)31-22)27(20)24(13-17)32-25(29)14-19-6-4-3-5-7-19/h3-9,12,17-18,21-24,27-28H,10-11,13-16H2,1-2H3/t17-,18-,21+,22+,23-,24-,27-/m0/s1	QXEJOEBXRQAVIM-KQGSDPMOSA-N	50009413	CHEMBL3085466::Phenyl-acetic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 19							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009413&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			12953878	103922425		CHEMBL3085466				ZINC26495661	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036976	CCCCCCCCCC(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C21H30O5/c1-12-8-15-5-4-13(2)18(21(15)19(9-12)25-14(3)22)7-6-17-10-16(23)11-20(24)26-17/h4-5,8,12-13,16-19,21,23H,6-7,9-11H2,1-3H3/t12-,13-,16+,17?,18-,19-,21?/m0/s1	ASSFTGNZZQBCNK-ZJLZVMLISA-N	50024634	Acetic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL3349959	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 295							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024634&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718667	103934739		CHEMBL3349959CHEMBL353049				ZINC27981186	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036977	C[C@@H]1C[C@H](OC(=O)C2CC2)C2[C@@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C23H32O5/c1-13-9-16-4-3-14(2)19(8-7-18-11-17(24)12-21(25)27-18)22(16)20(10-13)28-23(26)15-5-6-15/h3-4,9,13-15,17-20,22,24H,5-8,10-12H2,1-2H3/t13-,14-,17+,18?,19-,20-,22?/m0/s1	DHTCRYGDMZYDPH-VXBAJEPYSA-N	50024636	CHEMBL3349953::Cyclopropanecarboxylic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 39							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024636&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718661	103934741		CHEMBL3349953CHEMBL170906				ZINC27981951	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036978	C[C@@H]1C[C@H](OC(=O)C(C)(C)C)C2[C@@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C27H42O5/c1-6-27(7-2,8-3)26(30)32-23-14-17(4)13-19-10-9-18(5)22(25(19)23)12-11-21-15-20(28)16-24(29)31-21/h9-10,13,17-18,20-23,25,28H,6-8,11-12,14-16H2,1-5H3/t17-,18-,20+,21?,22-,23-,25?/m0/s1	YNAMVFSBFMILIU-OZSAVBCCSA-N	50024637	2,2-Diethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL3349950	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.7							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024637&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718658	103934742		CHEMBL3349950CHEMBL165524				ZINC27899046	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036982	C[C@@H]1C[C@H](OC(=O)C23CC4CC(CC(C4)C2)C3)C2[C@@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C30H42O5/c1-17-7-22-4-3-18(2)25(6-5-24-12-23(31)13-27(32)34-24)28(22)26(8-17)35-29(33)30-14-19-9-20(15-30)11-21(10-19)16-30/h3-4,7,17-21,23-26,28,31H,5-6,8-16H2,1-2H3/t17-,18-,19?,20?,21?,23+,24?,25-,26-,28?,30?/m0/s1	JXVOMXGNOYNHJJ-PVKFUUDVSA-N	50024638	Adamantane-1-carboxylic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester: 1/20 C6H12::CHEMBL3349946	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.8							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024638&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718654	103934743		CHEMBL3349946CHEMBL352558				ZINC27982057	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036983	C[C@@H]1C[C@H](OC(=O)C=C(C)C)C2[C@@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C24H34O5/c1-14(2)9-22(26)29-21-11-15(3)10-17-6-5-16(4)20(24(17)21)8-7-19-12-18(25)13-23(27)28-19/h5-6,9-10,15-16,18-21,24-25H,7-8,11-13H2,1-4H3/t15-,16-,18+,19?,20-,21-,24?/m0/s1	IPTAYEGJXGBMNA-YXUFBLGQSA-N	50024639	3-Methyl-but-2-enoic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL3349945	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 27							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024639&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718653	103934744		CHEMBL3349945CHEMBL423272				ZINC27984940	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50036984	C[C@@H]1C[C@H](OC(=O)CC(C)=C)C2[C@@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H](C)C=CC2=C1	InChI=1S/C24H34O5/c1-14(2)9-22(26)29-21-11-15(3)10-17-6-5-16(4)20(24(17)21)8-7-19-12-18(25)13-23(27)28-19/h5-6,10,15-16,18-21,24-25H,1,7-9,11-13H2,2-4H3/t15-,16-,18+,19?,20-,21-,24?/m0/s1	BNRLDMPZMGTURX-YXUFBLGQSA-N	50024642	3-Methyl-but-3-enoic acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL3349954	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.9							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024642	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024642&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718662	103934747		CHEMBL3349954CHEMBL168884				ZINC27983343	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039115	CCCCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O	InChI=1S/C20H38O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(25,16-18(21)22)17-19(23)24/h25H,2-17H2,1H3,(H,21,22)(H,23,24)	XIMVZSLUNQIRJQ-UHFFFAOYSA-N	50026334	3-Hydroxy-3-pentadecyl-pentanedioic acid::CHEMBL156576	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 50000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026334	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026334&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370337	103936044		CHEMBL156576				ZINC43422619	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039116	CCCCCCCCCCCCCCCC1(O)CCOC(O)C1	InChI=1S/C20H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(22)16-17-23-19(21)18-20/h19,21-22H,2-18H2,1H3	KYMFODLUDGMRFR-UHFFFAOYSA-N	50026335	4-Pentadecyl-tetrahydro-pyran-2,4-diol::CHEMBL154775	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1000000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026335&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370937	103936045		CHEMBL154775				ZINC43411787	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039117	CCCCCCCCCCCCCCCC(O)(CC(=O)OCC)CC(=O)OCC	InChI=1S/C24H46O5/c1-4-7-8-9-10-11-12-13-14-15-16-17-18-19-24(27,20-22(25)28-5-2)21-23(26)29-6-3/h27H,4-21H2,1-3H3	HRVMNSGMXRHSGM-UHFFFAOYSA-N	50026336	3-Hydroxy-3-pentadecyl-pentanedioic acid diethyl ester::CHEMBL156008	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026336&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370740	103936046		CHEMBL156008				ZINC43411904	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039118	CCCCCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O	InChI=1S/C21H40O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21(26,17-19(22)23)18-20(24)25/h26H,2-18H2,1H3,(H,22,23)(H,24,25)	QOHXHBONYSQTOT-UHFFFAOYSA-N	50026337	3-Hexadecyl-3-hydroxy-pentanedioic acid::CHEMBL155977	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026337	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026337&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370339	103936047		CHEMBL155977				ZINC43422556	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039119	CCCCCCCCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O	InChI=1S/C24H46O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24(29,20-22(25)26)21-23(27)28/h29H,2-21H2,1H3,(H,25,26)(H,27,28)	KSLRSQJENOPVQK-UHFFFAOYSA-N	50026338	3-Hydroxy-3-nonadecyl-pentanedioic acid::CHEMBL158184	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 350000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026338&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370921	103936048		CHEMBL158184				ZINC43422707	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039120	CCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O	InChI=1S/C18H34O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-18(23,14-16(19)20)15-17(21)22/h23H,2-15H2,1H3,(H,19,20)(H,21,22)	WDULOWKEKKMRTQ-UHFFFAOYSA-N	50026339	3-Hydroxy-3-tridecyl-pentanedioic acid::CHEMBL155789	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 50000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026339&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370507	103936049		CHEMBL155789				ZINC43411926	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039121	CCCCCCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O	InChI=1S/C22H42O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(27,18-20(23)24)19-21(25)26/h27H,2-19H2,1H3,(H,23,24)(H,25,26)	YMEXRAQNYJEAME-UHFFFAOYSA-N	50026340	3-Heptadecyl-3-hydroxy-pentanedioic acid::CHEMBL156577	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026340&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370338	103936050		CHEMBL156577				ZINC43422620	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039122	CCCCCCCCCCCCCCCC(O)(CC(O)=O)CC(=O)OCC	InChI=1S/C22H42O5/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-22(26,18-20(23)24)19-21(25)27-4-2/h26H,3-19H2,1-2H3,(H,23,24)	DTOFHRLUBVJPQF-UHFFFAOYSA-N	50026341	3-Hydroxy-3-pentadecyl-pentanedioic acid monoethyl ester::CHEMBL157719	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 900000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026341&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370739	103936051		CHEMBL157719				ZINC43422663	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039123	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039124	CCCCCCCCCCCCCCCC1(O)CC(=O)OC(=O)C1	InChI=1S/C20H36O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(23)16-18(21)24-19(22)17-20/h23H,2-17H2,1H3	IVSLDVWBHLLTCI-UHFFFAOYSA-N	50026342	4-Hydroxy-4-pentadecyl-dihydro-pyran-2,6-dione::CHEMBL155172	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 250000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026342&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370486	103936052		CHEMBL155172				ZINC43422591	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039125	CCCCCCCCCCCCCCC(O)(CC(O)=O)CC(O)=O	InChI=1S/C19H36O5/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-19(24,15-17(20)21)16-18(22)23/h24H,2-16H2,1H3,(H,20,21)(H,22,23)	HXVIICSLOWEDCX-UHFFFAOYSA-N	50026343	3-Hydroxy-3-tetradecyl-pentanedioic acid::CHEMBL157896	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 130000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026343&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370336	103936053		CHEMBL157896				ZINC43422676	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039126	CCCCCCCCCCC(O)(CC(O)=O)CC(O)=O	InChI=1S/C15H28O5/c1-2-3-4-5-6-7-8-9-10-15(20,11-13(16)17)12-14(18)19/h20H,2-12H2,1H3,(H,16,17)(H,18,19)	NPQGZHYAXAOWQE-UHFFFAOYSA-N	50026344	3-Decyl-3-hydroxy-pentanedioic acid::CHEMBL154728	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026344&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370363	103936054		CHEMBL154728				ZINC43411822	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50039127	CCCCCCCCCCCCCCCC1(O)CCOC(=O)C1	InChI=1S/C20H38O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(22)16-17-23-19(21)18-20/h22H,2-18H2,1H3	DIDBIIFLZIVTON-UHFFFAOYSA-N	50026345	4-Hydroxy-4-pentadecyl-tetrahydro-pyran-2-one::CHEMBL155612	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 750000							ChEMBL	10.1021/jm50001a011	10.7270/Q2QV3KHN	3989819			Baran, JS; Laos, I; Langford, DD; Miller, JE; Jett, C; Taite, B; Rohrbacher, E	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026345&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44370938	103936055		CHEMBL155612				ZINC43411948	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50037238	O[C@@H]1C[C@H](OC(=O)C1)C=C1c2ccccc2-c2ccccc12	InChI=1S/C19H16O3/c20-12-9-13(22-19(21)10-12)11-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,11-13,20H,9-10H2/t12-,13+/m1/s1	CQRTWQUVDHQCCK-OLZOCXBDSA-N	50024971	6-Fluoren-9-ylidenemethyl-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2367922	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 890							ChEMBL	10.1021/jm00155a041	10.7270/Q22F7MFN	3701793			Stokker, GE; Alberts, AW; Gilfillan, JL; Huff, JW; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024971	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024971&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73351395	103934941		CHEMBL2367922				ZINC27182644	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50037239	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1ccc(F)cc1	InChI=1S/C19H15Cl2FO3/c20-12-7-17(11-1-3-13(22)4-2-11)16(18(21)8-12)6-5-15-9-14(23)10-19(24)25-15/h1-8,14-15,23H,9-10H2/b6-5+/t14-,15-/m1/s1	VMMVXGKAALDTIC-XEVLESSRSA-N	50024972	(+) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::(-) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368970	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 24							ChEMBL	10.1021/jm00155a041	10.7270/Q22F7MFN	3701793			Stokker, GE; Alberts, AW; Gilfillan, JL; Huff, JW; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024972&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			12802879	103934942		CHEMBL2368970				ZINC29480073	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50037240	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1ccccc1	InChI=1S/C19H16Cl2O3/c20-13-8-17(12-4-2-1-3-5-12)16(18(21)9-13)7-6-15-10-14(22)11-19(23)24-15/h1-9,14-15,22H,10-11H2/b7-6+/t14-,15-/m1/s1	YUDDKXRBCZPNFK-WLBISTCBSA-N	50024973	6-[2-(3,5-Dichloro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368975	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 80							ChEMBL	10.1021/jm00155a041	10.7270/Q22F7MFN	3701793			Stokker, GE; Alberts, AW; Gilfillan, JL; Huff, JW; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024973	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024973&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354434	103934943		CHEMBL2368975				ZINC29480419	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50037241	Cc1cc(C)cc(c1)-c1cc(C)cc(C)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C23H26O3/c1-14-7-15(2)10-18(9-14)22-11-16(3)8-17(4)21(22)6-5-20-12-19(24)13-23(25)26-20/h5-11,19-20,24H,12-13H2,1-4H3/b6-5+/t19-,20-/m1/s1	KNMFROHCOSXVOB-BGEOSOQGSA-N	50024974	4-Hydroxy-6-[2-(3,5,3'',5''-tetramethyl-biphenyl-2-yl)-vinyl]-tetrahydro-pyran-2-one::CHEMBL2368982	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15							ChEMBL	10.1021/jm00155a041	10.7270/Q22F7MFN	3701793			Stokker, GE; Alberts, AW; Gilfillan, JL; Huff, JW; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024974	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024974&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352930	103934944		CHEMBL2368982				ZINC29482126	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50037242	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccccc1-c1ccccc1	InChI=1S/C19H18O3/c20-16-12-17(22-19(21)13-16)11-10-15-8-4-5-9-18(15)14-6-2-1-3-7-14/h1-11,16-17,20H,12-13H2/b11-10+/t16-,17-/m1/s1	YBRPATLKZYVIDP-XXRWXEQKSA-N	50024976	6-(2-Biphenyl-2-yl-vinyl)-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368911	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3000							ChEMBL	10.1021/jm00155a041	10.7270/Q22F7MFN	3701793			Stokker, GE; Alberts, AW; Gilfillan, JL; Huff, JW; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024976&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345350	103934946		CHEMBL2368911				ZINC29409116	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50037243	Cc1cc2-c3ccccc3\C(=C/[C@@H]3C[C@@H](O)CC(=O)O3)c2c(C)c1	InChI=1S/C21H20O3/c1-12-7-13(2)21-18(8-12)16-5-3-4-6-17(16)19(21)11-15-9-14(22)10-20(23)24-15/h3-8,11,14-15,22H,9-10H2,1-2H3/b19-11+/t14-,15+/m1/s1	GLYCFAPDFGJCMI-UALMWKMKSA-N	50024975	6-(1,3-Dimethyl-fluoren-9-ylidenemethyl)-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368316	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 750							ChEMBL	10.1021/jm00155a041	10.7270/Q22F7MFN	3701793			Stokker, GE; Alberts, AW; Gilfillan, JL; Huff, JW; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024975&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73351423	103934945		CHEMBL2368316				ZINC27978610	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50037244	Cc1cc2\C(=C/[C@@H]3C[C@@H](O)CC(=O)O3)c3c(cc(C)cc3C)-c2c(C)c1	InChI=1S/C23H24O3/c1-12-5-14(3)22-18(7-12)19(11-17-9-16(24)10-21(25)26-17)23-15(4)6-13(2)8-20(22)23/h5-8,11,16-17,24H,9-10H2,1-4H3/b19-11+/t16-,17+/m1/s1	YJDJAAUKUBEUGL-SGNWVPJISA-N	50024978	4-Hydroxy-6-(1,3,5,7-tetramethyl-fluoren-9-ylidenemethyl)-tetrahydro-pyran-2-one::CHEMBL2368319	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 830.0							ChEMBL	10.1021/jm00155a041	10.7270/Q22F7MFN	3701793			Stokker, GE; Alberts, AW; Gilfillan, JL; Huff, JW; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024978	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024978&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345309	103934948		CHEMBL2368319				ZINC27993333	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50037245	O[C@@H]1CC(CC2c3ccc(F)cc3-c3cc(Cl)cc(Cl)c23)OC(=O)C1	InChI=1S/C19H15Cl2FO3/c20-9-3-15-14-5-10(22)1-2-13(14)16(19(15)17(21)4-9)8-12-6-11(23)7-18(24)25-12/h1-5,11-12,16,23H,6-8H2/t11-,12?,16?/m1/s1	YUWQCFRCQVGNKQ-OPGSHWCFSA-N	50024977	6-(1,3-Dichloro-6-fluoro-9H-fluoren-9-ylmethyl)-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL424546	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 85.0							ChEMBL	10.1021/jm00155a041	10.7270/Q22F7MFN	3701793			Stokker, GE; Alberts, AW; Gilfillan, JL; Huff, JW; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024977	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024977&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44381199	103934947		CHEMBL424546		2974		ZINC27981303	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038798	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1ccco1	InChI=1S/C18H16Cl2O5/c19-11-6-16(20)15(4-3-13-8-12(21)9-18(22)25-13)17(7-11)24-10-14-2-1-5-23-14/h1-7,12-13,21H,8-10H2/b4-3+/t12-,13-/m1/s1	XOAHTMYZYSBTNJ-CDJBXZAQSA-N	50026090	6-{2-[2,4-Dichloro-6-(furan-2-ylmethoxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368890	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 600							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026090&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354431	103935824		CHEMBL2368890				ZINC29411161	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038800	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1cccc(F)c1	InChI=1S/C20H17Cl2FO4/c21-13-7-18(22)17(5-4-16-9-15(24)10-20(25)27-16)19(8-13)26-11-12-2-1-3-14(23)6-12/h1-8,15-16,24H,9-11H2/b5-4+/t15-,16-/m1/s1	WZOSJIRHTJHMGO-FZZYSBJUSA-N	50026094	6-{2-[2,4-Dichloro-6-(3-fluoro-benzyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368889	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 580							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026094&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345347	103935828		CHEMBL2368889				ZINC29413140	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038801	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCCCc1ccccc1	InChI=1S/C22H22Cl2O4/c23-16-11-20(24)19(9-8-18-13-17(25)14-22(26)28-18)21(12-16)27-10-4-7-15-5-2-1-3-6-15/h1-3,5-6,8-9,11-12,17-18,25H,4,7,10,13-14H2/b9-8+/t17-,18-/m1/s1	IONSZDAOHHEDNZ-RKQNLGICSA-N	50026092	6-{2-[2,4-Dichloro-6-(3-phenyl-propoxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368922	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1450							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026092	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026092&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356007	103935826		CHEMBL2368922				ZINC29412643	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038802	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1ccc(cc1)C#N	InChI=1S/C21H17Cl2NO4/c22-15-7-19(23)18(6-5-17-9-16(25)10-21(26)28-17)20(8-15)27-12-14-3-1-13(11-24)2-4-14/h1-8,16-17,25H,9-10,12H2/b6-5+/t16-,17-/m1/s1	JUNJVPLXYNEFDV-SDKBWNRFSA-N	50026093	4-{3,5-Dichloro-2-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-vinyl]-phenoxymethyl}-benzonitrile::CHEMBL2368875	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026093	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026093&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354429	103935827		CHEMBL2368875				ZINC29410880	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038803	COCCOCOc1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C17H20Cl2O6/c1-22-4-5-23-10-24-16-7-11(18)6-15(19)14(16)3-2-13-8-12(20)9-17(21)25-13/h2-3,6-7,12-13,20H,4-5,8-10H2,1H3/b3-2+/t12-,13-/m1/s1	FNRPSMYZZQFSQR-XCUNLHGCSA-N	50026096	6-{2-[2,4-Dichloro-6-(2-methoxy-ethoxymethoxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368901	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 11000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026096&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352923	103935830		CHEMBL2368901				ZINC29408681	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038804	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(OCc2ccccc2)cc1Cl	InChI=1S/C20H18Cl2O4/c21-18-10-16(25-12-13-4-2-1-3-5-13)11-19(22)17(18)7-6-15-8-14(23)9-20(24)26-15/h1-7,10-11,14-15,23H,8-9,12H2/b7-6+/t14-,15-/m1/s1	DXBBUPDMVFEJNJ-WLBISTCBSA-N	50026095	6-[2-(4-Benzyloxy-2,6-dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368894	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 450							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026095	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026095&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73351456	103935829		CHEMBL2368894				ZINC29409240	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038805	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccccc1Cl	InChI=1S/C13H13ClO3/c14-12-4-2-1-3-9(12)5-6-11-7-10(15)8-13(16)17-11/h1-6,10-11,15H,7-8H2/b6-5+/t10-,11-/m1/s1	MWTMHMDSZNWXEW-XIJCSBCJSA-N	50026097	6-[2-(2-Chloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368900	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7400							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026097&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73349957	103935831		CHEMBL2368900				ZINC29408675	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038806	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1ccccc1F	InChI=1S/C20H17Cl2FO4/c21-13-7-17(22)16(6-5-15-9-14(24)10-20(25)27-15)19(8-13)26-11-12-3-1-2-4-18(12)23/h1-8,14-15,24H,9-11H2/b6-5+/t14-,15-/m1/s1	JOCPRPQYCUGFGM-XEVLESSRSA-N	50026098	6-{2-[2,4-Dichloro-6-(2-fluoro-benzyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368910	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 510							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026098	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026098&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356004	103935832		CHEMBL2368910				ZINC29413934	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038807	O[C@@H]1CC(CCc2c(Cl)cc(Cl)cc2Oc2ccccc2)OC(=O)C1	InChI=1S/C19H18Cl2O4/c20-12-8-17(21)16(7-6-15-10-13(22)11-19(23)25-15)18(9-12)24-14-4-2-1-3-5-14/h1-5,8-9,13,15,22H,6-7,10-11H2/t13-,15?/m1/s1	ZBNAMUVLVVWNNE-AFYYWNPRSA-N	50026099	6-[2-(2,4-Dichloro-6-phenoxy-phenyl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL47537	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 330							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026099	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026099&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44291741	103935833		CHEMBL47537				ZINC29409006	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038808	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1ccc(Cl)cc1	InChI=1S/C20H17Cl3O4/c21-13-3-1-12(2-4-13)11-26-19-8-14(22)7-18(23)17(19)6-5-16-9-15(24)10-20(25)27-16/h1-8,15-16,24H,9-11H2/b6-5+/t15-,16-/m1/s1	MSLQYFMUGCNWOJ-DOOVEFGSSA-N	50026100	6-{2-[2,4-Dichloro-6-(4-chloro-benzyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368876	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2500							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026100	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026100&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73355997	103935834		CHEMBL2368876				ZINC29411167	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038809	Cc1ccc(COc2cc(Cl)cc(Cl)c2\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)cc1	InChI=1S/C21H20Cl2O4/c1-13-2-4-14(5-3-13)12-26-20-9-15(22)8-19(23)18(20)7-6-17-10-16(24)11-21(25)27-17/h2-9,16-17,24H,10-12H2,1H3/b7-6+/t16-,17-/m1/s1	PDTMNWKGLJLBSQ-KGVXHEBISA-N	50026101	6-{2-[2,4-Dichloro-6-(4-methyl-benzyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368920	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4900							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026101&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73346876	103935835		CHEMBL2368920				ZINC29413798	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038810	CCCCCOc1c(Cl)cc(Cl)cc1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H22Cl2O4/c1-2-3-4-7-23-18-12(8-13(19)9-16(18)20)5-6-15-10-14(21)11-17(22)24-15/h5-6,8-9,14-15,21H,2-4,7,10-11H2,1H3/b6-5+/t14-,15-/m1/s1	QSIRJZYRKYCFTN-XEVLESSRSA-N	50026102	6-[2-(3,5-Dichloro-2-pentyloxy-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368914	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026102&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356006	103935836		CHEMBL2368914				ZINC29410426	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038813	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1cccc2ccccc12	InChI=1S/C24H20Cl2O4/c25-17-10-22(26)21(9-8-19-12-18(27)13-24(28)30-19)23(11-17)29-14-16-6-3-5-15-4-1-2-7-20(15)16/h1-11,18-19,27H,12-14H2/b9-8+/t18-,19-/m1/s1	STTWYTZBAZKFCT-TYFAACHXSA-N	50026104	6-{2-[2,4-Dichloro-6-(naphthalen-1-ylmethoxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368917	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4400							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026104	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026104&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348381	103935838		CHEMBL2368917				ZINC29412153	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038814	O[C@@H]1CC(CCc2c(O)cc(Cl)cc2Cl)OC(=O)C1	InChI=1S/C13H14Cl2O4/c14-7-3-11(15)10(12(17)4-7)2-1-9-5-8(16)6-13(18)19-9/h3-4,8-9,16-17H,1-2,5-6H2/t8-,9?/m1/s1	OJDJKUIUYOLVND-VEDVMXKPSA-N	50026103	6-[2-(2,4-Dichloro-6-hydroxy-phenyl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL46049	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7900							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026103	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026103&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44291937	103935837		CHEMBL46049				ZINC29413716	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038815	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCCc1ccccc1	InChI=1S/C21H20Cl2O4/c22-15-10-19(23)18(7-6-17-12-16(24)13-21(25)27-17)20(11-15)26-9-8-14-4-2-1-3-5-14/h1-7,10-11,16-17,24H,8-9,12-13H2/b7-6+/t16-,17-/m1/s1	CXWIRFKDKJUFDY-KGVXHEBISA-N	50026105	6-[2-(2,4-Dichloro-6-phenethyloxy-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368919	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 480							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026105&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348383	103935839		CHEMBL2368919				ZINC29408070	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038816	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccccc1	InChI=1S/C13H14O3/c14-11-8-12(16-13(15)9-11)7-6-10-4-2-1-3-5-10/h1-7,11-12,14H,8-9H2/b7-6+/t11-,12-/m1/s1	LATSAVAHDMSYNE-BYAJROORSA-N	50026106	4-Hydroxy-6-styryl-tetrahydro-pyran-2-one::CHEMBL2368867	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 284000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026106&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11106830	103935840		CHEMBL2368867				ZINC29405629	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038817	O[C@@H]1CC(CCc2c(Cl)cc(Cl)cc2OCc2ccc(cc2)C(F)(F)F)OC(=O)C1	InChI=1S/C21H19Cl2F3O4/c22-14-7-18(23)17(6-5-16-9-15(27)10-20(28)30-16)19(8-14)29-11-12-1-3-13(4-2-12)21(24,25)26/h1-4,7-8,15-16,27H,5-6,9-11H2/t15-,16?/m1/s1	IIIZYAPPZAOYNH-AAFJCEBUSA-N	50026108	6-{2-[2,4-Dichloro-6-(4-trifluoromethyl-benzyloxy)-phenyl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL298223	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026108&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44291835	103935842		CHEMBL298223				ZINC29413130	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038818	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccc(OCc2ccc(F)cc2)c(Cl)c1Cl	InChI=1S/C20H17Cl2FO4/c21-19-13(3-7-16-9-15(24)10-18(25)27-16)4-8-17(20(19)22)26-11-12-1-5-14(23)6-2-12/h1-8,15-16,24H,9-11H2/b7-3+/t15-,16-/m1/s1	WFNUYWHHWZXZKY-SULOOQPXSA-N	50026107	6-{2-[2,3-Dichloro-4-(4-fluoro-benzyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368916	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 17000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026107&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73346875	103935841		CHEMBL2368916				ZINC29410448	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038819	O[C@@H]1CC(CCc2c(Cl)cc(Cl)cc2OCc2ccccc2F)OC(=O)C1	InChI=1S/C20H19Cl2FO4/c21-13-7-17(22)16(6-5-15-9-14(24)10-20(25)27-15)19(8-13)26-11-12-3-1-2-4-18(12)23/h1-4,7-8,14-15,24H,5-6,9-11H2/t14-,15?/m1/s1	KBXLOWLAFZODNL-GICMACPYSA-N	50026111	6-{2-[2,4-Dichloro-6-(2-fluoro-benzyloxy)-phenyl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL295300	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 150							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026111&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44292103	103935845		CHEMBL295300				ZINC29408814	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038820	CCCCCOc1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H22Cl2O4/c1-2-3-4-7-23-17-9-12(19)8-16(20)15(17)6-5-14-10-13(21)11-18(22)24-14/h5-6,8-9,13-14,21H,2-4,7,10-11H2,1H3/b6-5+/t13-,14-/m1/s1	QJGVCXKYRJLREB-QAMKJQMISA-N	50026110	6-[2-(2,4-Dichloro-6-pentyloxy-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368918	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026110&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348382	103935844		CHEMBL2368918				ZINC29409419	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038822	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCCOc1ccc(Cl)cc1	InChI=1S/C21H19Cl3O5/c22-13-1-3-16(4-2-13)27-7-8-28-20-10-14(23)9-19(24)18(20)6-5-17-11-15(25)12-21(26)29-17/h1-6,9-10,15,17,25H,7-8,11-12H2/b6-5+/t15-,17-/m1/s1	FXHBEJHKCYJEJO-AMFYOEQGSA-N	50026109	6-(2-{2,4-Dichloro-6-[2-(4-chloro-phenoxy)-ethoxy]-phenyl}-vinyl)-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368921	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026109&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73349959	103935843		CHEMBL2368921				ZINC29412619	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038823	COc1ccc(COc2cc(Cl)cc(Cl)c2\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)cc1	InChI=1S/C21H20Cl2O5/c1-26-16-4-2-13(3-5-16)12-27-20-9-14(22)8-19(23)18(20)7-6-17-10-15(24)11-21(25)28-17/h2-9,15,17,24H,10-12H2,1H3/b7-6+/t15-,17-/m1/s1	KNXFUSHXTLKHKG-RUBBHVMPSA-N	50026115	6-{2-[2,4-Dichloro-6-(4-methoxy-benzyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368908	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2600							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026115&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73349958	103935849		CHEMBL2368908				ZINC29412241	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038824	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OC\C=C\c1ccccc1	InChI=1S/C22H20Cl2O4/c23-16-11-20(24)19(9-8-18-13-17(25)14-22(26)28-18)21(12-16)27-10-4-7-15-5-2-1-3-6-15/h1-9,11-12,17-18,25H,10,13-14H2/b7-4+,9-8+/t17-,18-/m1/s1	XDMKMXBHKVLFCC-FTAQYQEZSA-N	50026114	6-{2-[2,4-Dichloro-6-(3-phenyl-allyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368886	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1900							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026114&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345346	103935848		CHEMBL2368886				ZINC29409170	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038825	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1ccc[n+]([O-])c1	InChI=1S/C19H17Cl2NO5/c20-13-6-17(21)16(4-3-15-8-14(23)9-19(24)27-15)18(7-13)26-11-12-2-1-5-22(25)10-12/h1-7,10,14-15,23H,8-9,11H2/b4-3+/t14-,15-/m1/s1	OBNTUDXSGCFKRT-LRPXVYOUSA-N	50026113	6-{2-[2,4-Dichloro-6-(1-oxy-pyridin-3-ylmethoxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368892	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 122000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026113&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345348	103935847		CHEMBL2368892				ZINC29407949	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038826	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1cc[n+]([O-])cc1	InChI=1S/C19H17Cl2NO5/c20-13-7-17(21)16(2-1-15-9-14(23)10-19(24)27-15)18(8-13)26-11-12-3-5-22(25)6-4-12/h1-8,14-15,23H,9-11H2/b2-1+/t14-,15-/m1/s1	QOYQLVUXKAMVFE-RIVGAVQESA-N	50026124	6-{2-[2,4-Dichloro-6-(1-oxy-pyridin-4-ylmethoxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368933	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 117000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026124&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352925	103935858		CHEMBL2368933				ZINC29405741	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038828	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(OCc2ccc(F)cc2)cc1Cl	InChI=1S/C20H17Cl2FO4/c21-18-9-16(26-11-12-1-3-13(23)4-2-12)10-19(22)17(18)6-5-15-7-14(24)8-20(25)27-15/h1-6,9-10,14-15,24H,7-8,11H2/b6-5+/t14-,15-/m1/s1	BMVBROIFZTXUMR-XEVLESSRSA-N	50026117	6-{2-[2,6-Dichloro-4-(4-fluoro-benzyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368915	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 670.0							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026117&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345351	103935851		CHEMBL2368915				ZINC29410431	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038829	CC(CCOc1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)CC(C)(C)C	InChI=1S/C22H30Cl2O4/c1-14(13-22(2,3)4)7-8-27-20-10-15(23)9-19(24)18(20)6-5-17-11-16(25)12-21(26)28-17/h5-6,9-10,14,16-17,25H,7-8,11-13H2,1-4H3/b6-5+/t14?,16-,17-/m1/s1	JRHOEVICMIEMKV-YBHNTFMPSA-N	50026118	6-{2-[2,4-Dichloro-6-(3,5,5-trimethyl-hexyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368912	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 38000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026118&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73346874	103935852		CHEMBL2368912				ZINC29404779	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038830	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCCC12CC3CC(CC(C3)C1)C2	InChI=1S/C25H30Cl2O4/c26-18-8-22(27)21(2-1-20-10-19(28)11-24(29)31-20)23(9-18)30-4-3-25-12-15-5-16(13-25)7-17(6-15)14-25/h1-2,8-9,15-17,19-20,28H,3-7,10-14H2/b2-1+/t15?,16?,17?,19-,20-,25?/m1/s1	WQYSNIBXUZOHPM-OACVEHTFSA-N	50026119	6-{2-[2-(2-Adamantan-1-yl-ethoxy)-4,6-dichloro-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368907	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026119&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356003	103935853		CHEMBL2368907				ZINC29411780	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038831	O[C@@H]1CC(CCc2c(Cl)cc(Cl)cc2OCC2CCCCC2)OC(=O)C1	InChI=1S/C20H26Cl2O4/c21-14-8-18(22)17(7-6-16-10-15(23)11-20(24)26-16)19(9-14)25-12-13-4-2-1-3-5-13/h8-9,13,15-16,23H,1-7,10-12H2/t15-,16?/m1/s1	FYDXWMWLCSEPLS-AAFJCEBUSA-N	50026125	6-[2-(2,4-Dichloro-6-cyclohexylmethoxy-phenyl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL296915	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 750							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026125&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44291743	103935859		CHEMBL296915				ZINC29411773	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038832	Cc1cc(OCc2ccccc2)cc(C)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H24O4/c1-15-10-20(25-14-17-6-4-3-5-7-17)11-16(2)21(15)9-8-19-12-18(23)13-22(24)26-19/h3-11,18-19,23H,12-14H2,1-2H3/b9-8+/t18-,19-/m1/s1	ZDJABRMTSSZJFJ-TYFAACHXSA-N	50026123	6-[2-(4-Benzyloxy-2,6-dimethyl-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368905	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 620							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026123&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348380	103935857		CHEMBL2368905				ZINC29406068	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038833	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccc(Cl)c(Cl)c1	InChI=1S/C13H12Cl2O3/c14-11-4-2-8(5-12(11)15)1-3-10-6-9(16)7-13(17)18-10/h1-5,9-10,16H,6-7H2/b3-1+/t9-,10-/m1/s1	YFRVJUKVERVYCL-XTYQLPPYSA-N	50026116	6-[2-(3,4-Dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368904	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 35000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026116&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356002	103935850		CHEMBL2368904				ZINC29410778	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038834	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1ccncc1	InChI=1S/C19H17Cl2NO4/c20-13-7-17(21)16(2-1-15-9-14(23)10-19(24)26-15)18(8-13)25-11-12-3-5-22-6-4-12/h1-8,14-15,23H,9-11H2/b2-1+/t14-,15-/m1/s1	VBBMZLUDKPUZEJ-RIVGAVQESA-N	50026120	6-{2-[2,4-Dichloro-6-(pyridin-4-ylmethoxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368938	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3700							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026120&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345355	103935854		CHEMBL2368938				ZINC29410089	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038835	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccc(cc1)-c1ccccc1	InChI=1S/C19H18O3/c20-17-12-18(22-19(21)13-17)11-8-14-6-9-16(10-7-14)15-4-2-1-3-5-15/h1-11,17-18,20H,12-13H2/b11-8+/t17-,18-/m1/s1	BVPUXTZTKVLZNE-BBUPJTBGSA-N	50026121	6-(2-Biphenyl-4-yl-vinyl)-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368868	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 55000							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026121&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73349956	103935855		CHEMBL2368868				ZINC29405634	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038836	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cccc(Cl)c1Cl	InChI=1S/C13H12Cl2O3/c14-11-3-1-2-8(13(11)15)4-5-10-6-9(16)7-12(17)18-10/h1-5,9-10,16H,6-7H2/b5-4+/t9-,10-/m1/s1	HWKVNKAHWCZZNW-NUNSBDKSSA-N	50026126	6-[2-(2,3-Dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368893	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 64400.0							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026126&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352921	103935860		CHEMBL2368893				ZINC29410773	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038837	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1cccs1	InChI=1S/C18H16Cl2O4S/c19-11-6-16(20)15(4-3-13-8-12(21)9-18(22)24-13)17(7-11)23-10-14-2-1-5-25-14/h1-7,12-13,21H,8-10H2/b4-3+/t12-,13-/m1/s1	LPIRQOXRYHKRGR-CDJBXZAQSA-N	50026132	6-{2-[2,4-Dichloro-6-(thiophen-2-ylmethoxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368887	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 600							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026132	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026132&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354430	103935866		CHEMBL2368887				ZINC29413473	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038838	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1ccccn1	InChI=1S/C19H17Cl2NO4/c20-12-7-17(21)16(5-4-15-9-14(23)10-19(24)26-15)18(8-12)25-11-13-3-1-2-6-22-13/h1-8,14-15,23H,9-11H2/b5-4+/t14-,15-/m1/s1	WXHWCSHUPWJHQF-DPOFCPOHSA-N	50026122	6-{2-[2,4-Dichloro-6-(pyridin-2-ylmethoxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368939	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1200							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026122&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348384	103935856		CHEMBL2368939				ZINC29416629	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038839	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1c(F)c(F)c(F)c(F)c1F	InChI=1S/C20H13Cl2F5O4/c21-8-3-13(22)11(2-1-10-5-9(28)6-15(29)31-10)14(4-8)30-7-12-16(23)18(25)20(27)19(26)17(12)24/h1-4,9-10,28H,5-7H2/b2-1+/t9-,10-/m1/s1	PYNMVVVSTSOYAC-UFLMBTITSA-N	50026134	6-[2-(2,4-Dichloro-6-pentafluorophenylmethoxy-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368923	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 700							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026134	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026134&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356008	103935868		CHEMBL2368923				ZINC29408513	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038840	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1Oc1ccccc1	InChI=1S/C19H16Cl2O4/c20-12-8-17(21)16(7-6-15-10-13(22)11-19(23)25-15)18(9-12)24-14-4-2-1-3-5-14/h1-9,13,15,22H,10-11H2/b7-6+/t13-,15-/m1/s1	OJTHMHWHGOIVPG-ZNTRNPIHSA-N	50026130	6-[2-(2,4-Dichloro-6-phenoxy-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368906	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1100							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026130&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			70431729	103935864		CHEMBL2368906				ZINC29409011	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038841	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1ccccc1	InChI=1S/C20H18Cl2O4/c21-14-8-18(22)17(7-6-16-10-15(23)11-20(24)26-16)19(9-14)25-12-13-4-2-1-3-5-13/h1-9,15-16,23H,10-12H2/b7-6+/t15-,16-/m1/s1	YTUFBVSBCXFOAL-YCZSJOHXSA-N	50026131	6-[2-(2-Benzyloxy-4,6-dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368903	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 430.0							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026131	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026131&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			70431406	103935865		CHEMBL2368903				ZINC29411247	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038842	Cc1ccc(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(C)c1	InChI=1S/C15H18O3/c1-10-3-4-12(11(2)7-10)5-6-14-8-13(16)9-15(17)18-14/h3-7,13-14,16H,8-9H2,1-2H3/b6-5+/t13-,14-/m1/s1	NPZQWMBYGQRCHL-QAMKJQMISA-N	50026129	6-[2-(2,4-Dimethyl-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368897	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 29900							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026129&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356001	103935863		CHEMBL2368897				ZINC29403860	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038844	O[C@@H]1CC(CCc2c(Cl)cc(Cl)cc2OCc2cccc(F)c2)OC(=O)C1	InChI=1S/C20H19Cl2FO4/c21-13-7-18(22)17(5-4-16-9-15(24)10-20(25)27-16)19(8-13)26-11-12-2-1-3-14(23)6-12/h1-3,6-8,15-16,24H,4-5,9-11H2/t15-,16?/m1/s1	LESQYFONTGYRRR-AAFJCEBUSA-N	50026127	6-{2-[2,4-Dichloro-6-(3-fluoro-benzyloxy)-phenyl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL47378	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 210							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026127	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026127&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44291874	103935861		CHEMBL47378				ZINC29411556	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038845	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCC=C	InChI=1S/C16H16Cl2O4/c1-2-5-21-15-7-10(17)6-14(18)13(15)4-3-12-8-11(19)9-16(20)22-12/h2-4,6-7,11-12,19H,1,5,8-9H2/b4-3+/t11-,12-/m1/s1	ZYWWNHFTLVSKRP-BLDJZWNYSA-N	50026128	6-[2-(2-Allyloxy-4,6-dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368913	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 760							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026128&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356005	103935862		CHEMBL2368913				ZINC29408690	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038846	CSCOc1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C15H16Cl2O4S/c1-22-8-20-14-5-9(16)4-13(17)12(14)3-2-11-6-10(18)7-15(19)21-11/h2-5,10-11,18H,6-8H2,1H3/b3-2+/t10-,11-/m1/s1	UWMWVRDALNVQGU-WUNPDAOYSA-N	50026138	6-[2-(2,4-Dichloro-6-methylsulfanylmethoxy-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368895	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 760							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026138&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352922	103935872		CHEMBL2368895				ZINC29413852	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038848	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1cccnc1	InChI=1S/C19H17Cl2NO4/c20-13-6-17(21)16(4-3-15-8-14(23)9-19(24)26-15)18(7-13)25-11-12-2-1-5-22-10-12/h1-7,10,14-15,23H,8-9,11H2/b4-3+/t14-,15-/m1/s1	CPFXMGGSQKZGCE-LRPXVYOUSA-N	50026136	6-{2-[2,4-Dichloro-6-(pyridin-3-ylmethoxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368932	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3400							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026136&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354433	103935870		CHEMBL2368932				ZINC29413704	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038849	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cccc1Cl	InChI=1S/C13H12Cl2O3/c14-11-2-1-3-12(15)10(11)5-4-9-6-8(16)7-13(17)18-9/h1-5,8-9,16H,6-7H2/b5-4+/t8-,9-/m1/s1	JKLKMTBSXMRORM-HOMPQPGZSA-N	50026133	6-[2-(2,6-Dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368896	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7900							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026133	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026133&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345349	103935867		CHEMBL2368896				ZINC29408906	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038850	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1ccc(F)cc1F	InChI=1S/C20H16Cl2F2O4/c21-12-5-17(22)16(4-3-15-8-14(25)9-20(26)28-15)19(6-12)27-10-11-1-2-13(23)7-18(11)24/h1-7,14-15,25H,8-10H2/b4-3+/t14-,15-/m1/s1	MPJXGJJRCNOWNK-LRPXVYOUSA-N	50026135	6-{2-[2,4-Dichloro-6-(2,4-difluoro-benzyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368926	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 200							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026135	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026135&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356009	103935869		CHEMBL2368926				ZINC29408802	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038851	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OC(c1ccccc1)c1ccccc1	InChI=1S/C26H22Cl2O4/c27-19-13-23(28)22(12-11-21-15-20(29)16-25(30)31-21)24(14-19)32-26(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-14,20-21,26,29H,15-16H2/b12-11+/t20-,21-/m1/s1	UJUPQVJWWVQLAM-LKWCPCFXSA-N	50026139	6-[2-(2-Benzhydryloxy-4,6-dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368888	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6300							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026139&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73346872	103935873		CHEMBL2368888				ZINC29410154	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038852	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1OCc1ccc(F)cc1	InChI=1S/C20H17Cl2FO4/c21-13-7-18(22)17(6-5-16-9-15(24)10-20(25)27-16)19(8-13)26-11-12-1-3-14(23)4-2-12/h1-8,15-16,24H,9-11H2/b6-5+/t15-,16-/m1/s1	FQZXNMTTYNRQMB-DOOVEFGSSA-N	50026137	6-{2-[2,4-Dichloro-6-(4-fluoro-benzyloxy)-phenyl]-vinyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368891	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 200							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026137&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356000	103935871		CHEMBL2368891				ZINC29407943	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038854	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1cc(Cl)cc(Cl)c1	InChI=1S/C19H14Cl4O3/c20-11-3-10(4-12(21)5-11)17-6-13(22)7-18(23)16(17)2-1-15-8-14(24)9-19(25)26-15/h1-7,14-15,24H,8-9H2/b2-1+/t14-,15-/m1/s1	RHYLLCHYGSNOCD-RIVGAVQESA-N	50026141	4-Hydroxy-6-[2-(3,5,3',5'-tetrachloro-biphenyl-2-yl)-vinyl]-tetrahydro-pyran-2-one::CHEMBL2368989	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 37							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026141&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348390	103935875		CHEMBL2368989				ZINC29484420	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038855	O[C@@H]1CC(CCc2ccccc2-c2ccccc2)OC(=O)C1	InChI=1S/C19H20O3/c20-16-12-17(22-19(21)13-16)11-10-15-8-4-5-9-18(15)14-6-2-1-3-7-14/h1-9,16-17,20H,10-13H2/t16-,17?/m1/s1	VMACCCPBJYNCSA-TZHYSIJRSA-N	50026140	6-(2-Biphenyl-2-yl-ethyl)-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL50348	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 44000							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026140&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44296421	103935874		CHEMBL50348				ZINC29480413	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038856	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1ccc(Cl)c(Cl)c1	InChI=1S/C19H14Cl4O3/c20-11-6-15(10-1-4-16(21)18(23)5-10)14(17(22)7-11)3-2-13-8-12(24)9-19(25)26-13/h1-7,12-13,24H,8-9H2/b3-2+/t12-,13-/m1/s1	VRXHJOZTXMVLIU-XCUNLHGCSA-N	50026142	4-Hydroxy-6-[2-(3,5,3',4'-tetrachloro-biphenyl-2-yl)-vinyl]-tetrahydro-pyran-2-one::CHEMBL2368986	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026142	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026142&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354438	103935876		CHEMBL2368986				ZINC29480398	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038857	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1cccc(F)c1	InChI=1S/C19H15Cl2FO3/c20-12-7-17(11-2-1-3-13(22)6-11)16(18(21)8-12)5-4-15-9-14(23)10-19(24)25-15/h1-8,14-15,23H,9-10H2/b5-4+/t14-,15-/m1/s1	GFOPFSAUKIXHDS-DPOFCPOHSA-N	50026143	6-[2-(3,5-Dichloro-3'-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368978	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 70.0							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026143	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026143&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73349966	103935877		CHEMBL2368978				ZINC29482513	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038858	Cc1cc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(\C=C\c2ccc(Cl)cc2)c1	InChI=1S/C23H23ClO3/c1-15-11-16(2)22(10-9-21-13-20(25)14-23(26)27-21)18(12-15)6-3-17-4-7-19(24)8-5-17/h3-12,20-21,25H,13-14H2,1-2H3/b6-3+,10-9+/t20-,21-/m1/s1	KEVGEZYCEMHVMX-YYWGIEMPSA-N	50026145	6-(2-{2-[2-(4-Chloro-phenyl)-vinyl]-4,6-dimethyl-phenyl}-vinyl)-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368981	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 630							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026145	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026145&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354436	103935879		CHEMBL2368981				ZINC29484033	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038859	Cc1cc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(F)cc1	InChI=1S/C21H21FO3/c1-13-9-14(2)19(8-7-18-11-17(23)12-21(24)25-18)20(10-13)15-3-5-16(22)6-4-15/h3-10,17-18,23H,11-12H2,1-2H3/b8-7+/t17-,18-/m1/s1	HUGYGHGIFGCECH-HNGSOEQISA-N	50026144	6-[2-(4'-Fluoro-3,5-dimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368984	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026144	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026144&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73351460	103935878		CHEMBL2368984				ZINC29476868	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038860	Cc1cc(C)c(CCC2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(F)c(C)c1	InChI=1S/C22H25FO3/c1-13-8-14(2)19(6-5-18-11-17(24)12-22(25)26-18)20(9-13)16-4-7-21(23)15(3)10-16/h4,7-10,17-18,24H,5-6,11-12H2,1-3H3/t17-,18?/m1/s1	QTBNPOREZABRPH-QNSVNVJESA-N	50026147	6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL50566	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 22							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026147&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44296013	103935881		CHEMBL50566				ZINC29475100	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038861	CCc1cccc(c1)-c1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H20Cl2O3/c1-2-13-4-3-5-14(8-13)19-9-15(22)10-20(23)18(19)7-6-17-11-16(24)12-21(25)26-17/h3-10,16-17,24H,2,11-12H2,1H3/b7-6+/t16-,17-/m1/s1	IFCIKZUATCFKIX-KGVXHEBISA-N	50026146	6-[2-(3,5-Dichloro-3'-ethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368966	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 44							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026146&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345357	103935880		CHEMBL2368966				ZINC29483708	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038863	Cc1cc(Cl)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(F)c(C)c1	InChI=1S/C21H20ClFO3/c1-12-7-18(14-3-6-20(23)13(2)9-14)17(19(22)8-12)5-4-16-10-15(24)11-21(25)26-16/h3-9,15-16,24H,10-11H2,1-2H3/b5-4+/t15-,16-/m1/s1	MXPBKVOBCGEMAO-FZZYSBJUSA-N	50026148	6-[2-(3-Chloro-4'-fluoro-5,3'-dimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368974	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026148&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73346882	103935882		CHEMBL2368974				ZINC29481427	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038865	Cc1cc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(F)c(CO)c1	InChI=1S/C22H23FO4/c1-13-7-14(2)19(5-4-18-10-17(25)11-22(26)27-18)20(8-13)15-3-6-21(23)16(9-15)12-24/h3-9,17-18,24-25H,10-12H2,1-2H3/b5-4+/t17-,18-/m1/s1	QGRZLCDFHATGDQ-UBZMYNMCSA-N	50026150	6-[2-(4'-Fluoro-3'-hydroxymethyl-3,5-dimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368976	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 49							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026150&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13553304	103935884		CHEMBL2368976				ZINC29482120	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038866	Cc1cc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(F)c(C)c1	InChI=1S/C22H23FO3/c1-13-8-14(2)19(6-5-18-11-17(24)12-22(25)26-18)20(9-13)16-4-7-21(23)15(3)10-16/h4-10,17-18,24H,11-12H2,1-3H3/b6-5+/t17-,18-/m1/s1	BNIBDNOALUGLCI-PJHKVULZSA-N	50014669	6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL440891	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014669&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6439709	103926564		CHEMBL440891				ZINC06069734	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038867	Cc1ccc(C)c(-c2ccc(Cl)c(Cl)c2)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H20Cl2O3/c1-12-3-4-13(2)21(14-5-8-18(22)19(23)9-14)17(12)7-6-16-10-15(24)11-20(25)26-16/h3-9,15-16,24H,10-11H2,1-2H3/b7-6+/t15-,16-/m1/s1	JAYQKTKSWAHBPH-YCZSJOHXSA-N	50026152	6-[2-(3',4'-Dichloro-3,6-dimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368971	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026152	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026152&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345358	103935886		CHEMBL2368971				ZINC29483696	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038868	COc1cccc(c1)-c1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H18Cl2O4/c1-25-15-4-2-3-12(7-15)18-8-13(21)9-19(22)17(18)6-5-16-10-14(23)11-20(24)26-16/h2-9,14,16,23H,10-11H2,1H3/b6-5+/t14-,16-/m1/s1	IGUZZQUEDGLAGI-QNQFUXMYSA-N	50026154	6-[2-(3,5-Dichloro-3'-methoxy-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368965	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 50							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026154&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73346880	103935888		CHEMBL2368965				ZINC29483702	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038869	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1CCc1ccccc1	InChI=1S/C21H20Cl2O3/c22-16-10-15(7-6-14-4-2-1-3-5-14)19(20(23)11-16)9-8-18-12-17(24)13-21(25)26-18/h1-5,8-11,17-18,24H,6-7,12-13H2/b9-8+/t17-,18-/m1/s1	YHESAACRTZCEKR-RKQNLGICSA-N	50026153	6-[2-(2,4-Dichloro-6-phenethyl-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368967	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 430.0							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026153	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026153&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73351459	103935887		CHEMBL2368967				ZINC29478483	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038871	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(F)cc(F)cc1-c1ccc(F)cc1	InChI=1S/C19H15F3O3/c20-12-3-1-11(2-4-12)17-7-13(21)8-18(22)16(17)6-5-15-9-14(23)10-19(24)25-15/h1-8,14-15,23H,9-10H2/b6-5+/t14-,15-/m1/s1	GCAHUKVKFOSJJQ-XEVLESSRSA-N	50026155	4-Hydroxy-6-[2-(3,5,4'-trifluoro-biphenyl-2-yl)-vinyl]-tetrahydro-pyran-2-one::CHEMBL2368977	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 860.0							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026155	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026155&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348388	103935889		CHEMBL2368977				ZINC29482507	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038873	Cc1cc(ccc1F)-c1cccc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H18ClFO3/c1-12-9-13(5-8-19(12)22)16-3-2-4-18(21)17(16)7-6-15-10-14(23)11-20(24)25-15/h2-9,14-15,23H,10-11H2,1H3/b7-6+/t14-,15-/m1/s1	YUKSSJOXWUFEPS-WLBISTCBSA-N	50026156	6-[2-(3-Chloro-4'-fluoro-3'-methyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368979	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026156	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026156&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352929	103935890		CHEMBL2368979				ZINC29480210	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038875	Cc1cccc(c1)-c1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H18Cl2O3/c1-12-3-2-4-13(7-12)18-8-14(21)9-19(22)17(18)6-5-16-10-15(23)11-20(24)25-16/h2-9,15-16,23H,10-11H2,1H3/b6-5+/t15-,16-/m1/s1	ZGLHIJHYCDHUDG-DOOVEFGSSA-N	50026158	6-[2-(3,5-Dichloro-3',5'-dimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368964	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 16							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026158	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026158&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352928	103935892		CHEMBL2368964				ZINC29474430	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038877	O[C@@H]1CC(CCc2c(Cl)cc(Cl)cc2-c2ccccc2)OC(=O)C1	InChI=1S/C19H18Cl2O3/c20-13-8-17(12-4-2-1-3-5-12)16(18(21)9-13)7-6-15-10-14(22)11-19(23)24-15/h1-5,8-9,14-15,22H,6-7,10-11H2/t14-,15?/m1/s1	RBPAHNRDPAJTEZ-GICMACPYSA-N	50026157	6-[2-(3,5-Dichloro-biphenyl-2-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL54240	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026157	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026157&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44296185	103935891		CHEMBL54240				ZINC29482236	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038878	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccc(Cl)cc1Cl	InChI=1S/C13H12Cl2O3/c14-9-3-1-8(12(15)5-9)2-4-11-6-10(16)7-13(17)18-11/h1-5,10-11,16H,6-7H2/b4-2+/t10-,11-/m1/s1	BGASINALMIKBMK-JTNORFRNSA-N	50026112	6-[2-(2,4-Dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368928	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 21900							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026112&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			22822816	103935846		CHEMBL2368928				ZINC29409500	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038879	COc1ccc(cc1)-c1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H18Cl2O4/c1-25-15-4-2-12(3-5-15)18-8-13(21)9-19(22)17(18)7-6-16-10-14(23)11-20(24)26-16/h2-9,14,16,23H,10-11H2,1H3/b7-6+/t14-,16-/m1/s1	JKFLOFVMHTYRDG-XMAAMQLLSA-N	50026161	6-[2-(3,5-Dichloro-4'-methoxy-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368972	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 470							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026161	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026161&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73349965	103935895		CHEMBL2368972				ZINC29481715	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038880	Cc1ccccc1-c1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H18Cl2O3/c1-12-4-2-3-5-16(12)18-8-13(21)9-19(22)17(18)7-6-15-10-14(23)11-20(24)25-15/h2-9,14-15,23H,10-11H2,1H3/b7-6+/t14-,15-/m1/s1	KCBPOBJABJQYHI-WLBISTCBSA-N	50026162	6-[2-(3,5-Dichloro-2'-methyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368969	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 370							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026162	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026162&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73346881	103935896		CHEMBL2368969				ZINC29474900	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038881	Cc1ccc(cc1)-c1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H18Cl2O3/c1-12-2-4-13(5-3-12)18-8-14(21)9-19(22)17(18)7-6-16-10-15(23)11-20(24)25-16/h2-9,15-16,23H,10-11H2,1H3/b7-6+/t15-,16-/m1/s1	VCFQIKOGJCUJPG-YCZSJOHXSA-N	50026159	6-[2-(3,5-Dichloro-3'-methyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368963	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 190							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026159	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026159&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73349964	103935893		CHEMBL2368963				ZINC29481259	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038882	Cc1cc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(c1)-c1cc(C)c(F)c(C)c1	InChI=1S/C23H25FO3/c1-13-7-14(2)20(6-5-19-11-18(25)12-22(26)27-19)21(8-13)17-9-15(3)23(24)16(4)10-17/h5-10,18-19,25H,11-12H2,1-4H3/b6-5+/t18-,19-/m1/s1	ZVQCWCXKCFTMCM-ASIGSXEYSA-N	50026149	6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368968	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026149	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026149&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356011	103935883		CHEMBL2368968				ZINC29476566	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038883	O[C@@H]1CC(CCc2c(Cl)cc(Cl)cc2Cc2ccccc2)OC(=O)C1	InChI=1S/C20H20Cl2O3/c21-15-9-14(8-13-4-2-1-3-5-13)18(19(22)10-15)7-6-17-11-16(23)12-20(24)25-17/h1-5,9-10,16-17,23H,6-8,11-12H2/t16-,17?/m1/s1	DHNDRUZIHILXFQ-TZHYSIJRSA-N	50026160	6-[2-(2-Benzyl-4,6-dichloro-phenyl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL300495	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 530							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026160	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026160&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44296420	103935894		CHEMBL300495				ZINC29480407	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038884	Cc1cc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(Cl)c(Cl)c1	InChI=1S/C21H20Cl2O3/c1-12-7-13(2)17(5-4-16-10-15(24)11-21(25)26-16)18(8-12)14-3-6-19(22)20(23)9-14/h3-9,15-16,24H,10-11H2,1-2H3/b5-4+/t15-,16-/m1/s1	CFGOOJVHXZNZTH-FZZYSBJUSA-N	50026164	6-[2-(3',4'-Dichloro-3,5-dimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368988	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026164&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354441	103935898		CHEMBL2368988				ZINC29475895	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038885	Cc1cc(ccc1F)-c1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H17Cl2FO3/c1-11-6-12(2-5-19(11)23)17-7-13(21)8-18(22)16(17)4-3-15-9-14(24)10-20(25)26-15/h2-8,14-15,24H,9-10H2,1H3/b4-3+/t14-,15-/m1/s1	RAJPKMBITNCHGY-LRPXVYOUSA-N	50026163	6-[2-(3,5-Dichloro-4'-fluoro-3'-methyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368962	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 29							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026163&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73346879	103935897		CHEMBL2368962				ZINC29479079	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038886	CO[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(C)cc(C)cc1-c1ccc(F)c(C)c1	InChI=1S/C23H25FO3/c1-14-9-15(2)20(7-6-18-12-19(26-4)13-23(25)27-18)21(10-14)17-5-8-22(24)16(3)11-17/h5-11,18-19H,12-13H2,1-4H3/b7-6+/t18-,19-/m1/s1	PSZKUPIEYIROBL-LXORQPIJSA-N	50026166	6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vinyl]-4-methoxy-tetrahydro-pyran-2-one::CHEMBL2368983	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 106							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026166	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026166&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354437	103935900		CHEMBL2368983				ZINC29479018	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038887	Cc1cc(C)cc(c1)-c1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H20Cl2O3/c1-12-5-13(2)7-14(6-12)19-8-15(22)9-20(23)18(19)4-3-17-10-16(24)11-21(25)26-17/h3-9,16-17,24H,10-11H2,1-2H3/b4-3+/t16-,17-/m1/s1	LSLFRLOUXYMRHW-MULDZMIYSA-N	50026167	6-[2-(3,5-Dichloro-3'-methyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368985	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026167	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026167&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348389	103935901		CHEMBL2368985				ZINC29481265	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038889	Cc1cc(F)ccc1-c1cc(Cl)cc(Cl)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H17Cl2FO3/c1-11-6-13(23)2-4-16(11)18-7-12(21)8-19(22)17(18)5-3-15-9-14(24)10-20(25)26-15/h2-8,14-15,24H,9-10H2,1H3/b5-3+/t14-,15-/m1/s1	PCXIQBFRUSXXSI-UJOCRUBTSA-N	50026165	6-[2-(3,5-Dichloro-4'-fluoro-2'-methyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368980	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 36							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026165	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026165&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354435	103935899		CHEMBL2368980				ZINC29484229	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038890	Cc1cc(ccc1F)-c1cc(Cl)cc(C)c1\C=C\[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H20ClFO3/c1-12-8-15(22)9-19(14-3-6-20(23)13(2)7-14)18(12)5-4-17-10-16(24)11-21(25)26-17/h3-9,16-17,24H,10-11H2,1-2H3/b5-4+/t16-,17-/m1/s1	VVRWMJVGSUCUFZ-ADDHZHGLSA-N	50026169	6-[2-(5-Chloro-4'-fluoro-3,3'-dimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368973	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026169&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348387	103935903		CHEMBL2368973				ZINC29483234	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50038891	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1ccc(Cl)cc1	InChI=1S/C19H15Cl3O3/c20-12-3-1-11(2-4-12)17-7-13(21)8-18(22)16(17)6-5-15-9-14(23)10-19(24)25-15/h1-8,14-15,23H,9-10H2/b6-5+/t14-,15-/m1/s1	HJPDVBXXDZUBDN-XEVLESSRSA-N	50026168	4-Hydroxy-6-[2-(3,5,4'-trichloro-biphenyl-2-yl)-vinyl]-tetrahydro-pyran-2-one::CHEMBL2368990	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 36							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026168&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73356012	103935902		CHEMBL2368990				ZINC29484047	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50057277	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC([O-])=O)[C@@H]12	InChI=1S/C24H38O6/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28/h6-7,10,14-16,18-21,23,25-26H,5,8-9,11-13H2,1-4H3,(H,27,28)/p-1/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1	QLJODMDSTUBWDW-BXMDZJJMSA-M	50406129	CHEMBL175236	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1021/jm00096a015	10.7270/Q2HD7W9V	1527791			Bone, EA; Davidson, AH; Lewis, CN; Todd, RS	British Bio-technology Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50406129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50406129&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			40474546	163355153		CHEMBL175236			C03834	ZINC04134473	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50057278	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC([O-])=O)[C@@H]12	InChI=1S/C25H40O6.Na/c1-6-25(4,5)24(30)31-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-18(26)13-19(27)14-22(28)29;/h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29);/q;+1/p-1/t15-,16-,18+,19+,20-,21-,23-;/m0./s1	RLWRROYWKHUVKF-OKDJMAGBSA-M	50455629	CHEMBL487720	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00096a015	10.7270/Q2HD7W9V	1527791			Bone, EA; Davidson, AH; Lewis, CN; Todd, RS	British Bio-technology Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50455629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50455629&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			16760655	225146545		CHEMBL487720					1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50058086	CC[C@H](C)C(=O)O[C@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@H](O)CC[C@]23C)[C@@H]2CCC(CC[C@H]3C[C@@H](O)CC(=O)O3)[C@@]12C	InChI=1S/C31H50O6/c1-5-18(2)29(35)37-27-17-26-24(10-7-20-14-21(32)12-13-30(20,26)3)25-11-8-19(31(25,27)4)6-9-23-15-22(33)16-28(34)36-23/h18-27,32-33H,5-17H2,1-4H3/t18-,19?,20+,21+,22+,23-,24-,25-,26-,27-,30-,31+/m0/s1	CFMOEGAYJQXZMT-CPRASWMJSA-N	50037254	(S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R,14S)-3-hydroxy-17-[2-((2S,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-12-yl ester::CHEMBL321906	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1000							ChEMBL	10.1021/jm00046a007	10.7270/Q25H7F9D	7932551			Wess, G; Kramer, W; Han, XB; Bock, K; Enhsen, A; Glombik, H; Baringhaus, KH; Boger, G; Urmann, M; Hoffmann, A	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037254&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			10414283	103944804		CHEMBL321906				ZINC36243014	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50058087	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19?,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-KVVRZSONSA-N	50004774	(S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-((R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::(lovastatin)2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(mevinolin)::CHEMBL503	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.0							ChEMBL	10.1021/jm00046a007	10.7270/Q25H7F9D	7932551			Wess, G; Kramer, W; Han, XB; Bock, K; Enhsen, A; Glombik, H; Baringhaus, KH; Boger, G; Urmann, M; Hoffmann, A	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004774&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6420024	103918321		CHEMBL503				ZINC04245664	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50058088	CC[C@H](C)C(=O)O[C@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@H](O)CC[C@]23C)[C@@H]2CCC([C@H](C)C[C@H]3C[C@@H](O)CC(=O)O3)[C@@]12C	InChI=1S/C32H52O6/c1-6-18(2)30(36)38-28-17-27-24(8-7-20-14-21(33)11-12-31(20,27)4)26-10-9-25(32(26,28)5)19(3)13-23-15-22(34)16-29(35)37-23/h18-28,33-34H,6-17H2,1-5H3/t18-,19+,20+,21+,22+,23-,24-,25?,26-,27-,28-,31-,32+/m0/s1	UEMHFBBEKZCMAP-MXSVZMNGSA-N	50037256	(S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R,14S)-3-hydroxy-17-[(R)-2-((2S,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-1-methyl-ethyl]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-12-yl ester::CHEMBL322338	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7000							ChEMBL	10.1021/jm00046a007	10.7270/Q25H7F9D	7932551			Wess, G; Kramer, W; Han, XB; Bock, K; Enhsen, A; Glombik, H; Baringhaus, KH; Boger, G; Urmann, M; Hoffmann, A	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037256&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44339335	103944806		CHEMBL322338				ZINC36243005	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50058089	CC[C@H](C)C(=O)O[C@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@H](O)CC[C@]23C)[C@@H]2CCC(CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@]12C	InChI=1S/C31H50O6/c1-5-18(2)29(35)37-27-17-26-24(10-7-20-14-21(32)12-13-30(20,26)3)25-11-8-19(31(25,27)4)6-9-23-15-22(33)16-28(34)36-23/h18-27,32-33H,5-17H2,1-4H3/t18-,19?,20+,21+,22+,23+,24-,25-,26-,27-,30-,31+/m0/s1	CFMOEGAYJQXZMT-UQTJVAAQSA-N	50037255	(S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R,14S)-3-hydroxy-17-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-12-yl ester::CHEMBL320943	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 200							ChEMBL	10.1021/jm00046a007	10.7270/Q25H7F9D	7932551			Wess, G; Kramer, W; Han, XB; Bock, K; Enhsen, A; Glombik, H; Baringhaus, KH; Boger, G; Urmann, M; Hoffmann, A	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037255&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11756374	103944805		CHEMBL320943		3030		ZINC36243009	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50058090	CC[C@H](C)C(=O)O[C@H]1C[C@H]2[C@@H](CC[C@@H]3C[C@H](O)CC[C@]23C)[C@@H]2CCC([C@H](C)C[C@@H]3C[C@@H](O)CC(=O)O3)[C@@]12C	InChI=1S/C32H52O6/c1-6-18(2)30(36)38-28-17-27-24(8-7-20-14-21(33)11-12-31(20,27)4)26-10-9-25(32(26,28)5)19(3)13-23-15-22(34)16-29(35)37-23/h18-28,33-34H,6-17H2,1-5H3/t18-,19+,20+,21+,22+,23+,24-,25?,26-,27-,28-,31-,32+/m0/s1	UEMHFBBEKZCMAP-NJQIKHQVSA-N	50037257	(S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R,14S)-3-hydroxy-17-[(R)-2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-1-methyl-ethyl]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-12-yl ester::CHEMBL326894	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 650							ChEMBL	10.1021/jm00046a007	10.7270/Q25H7F9D	7932551			Wess, G; Kramer, W; Han, XB; Bock, K; Enhsen, A; Glombik, H; Baringhaus, KH; Boger, G; Urmann, M; Hoffmann, A	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50037257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50037257&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44339378	103944807		CHEMBL326894				ZINC36243001	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50061794	CC(C)c1nc(c(-c2ccc(F)cc2)n1\C=C\[C@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C25H26F2N2O4/c1-15(2)25-28-23(16-3-7-18(26)8-4-16)24(17-5-9-19(27)10-6-17)29(25)12-11-20(30)13-21(31)14-22(32)33/h3-12,15,20-21,30-31H,13-14H2,1-2H3,(H,32,33)/p-1/b12-11+/t20-,21+/m0/s1	GQOQQDINYJTQDY-LBNTZDJNSA-M	50160770	(E)-(3R,5R)-7-[4,5-Bis-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2000							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160770	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160770&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392530	104047230	29067				C03834	ZINC13833968	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50061795	CC(C)c1nc(c(-c2ccc(F)cc2)n1\C=C\[C@H](O)C[C@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C25H26F2N2O4/c1-15(2)25-28-23(16-3-7-18(26)8-4-16)24(17-5-9-19(27)10-6-17)29(25)12-11-20(30)13-21(31)14-22(32)33/h3-12,15,20-21,30-31H,13-14H2,1-2H3,(H,32,33)/p-1/b12-11+/t20-,21-/m0/s1	GQOQQDINYJTQDY-GOHIESPPSA-M	50160782	(E)-(3S,5R)-7-[4,5-Bis-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 700							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160782	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160782&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392520	104047242	29067				C03834	ZINC13833967	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067887	COc1ccc(cc1)-c1nc(n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1)C(F)(F)F	InChI=1S/C24H24F4N2O5/c1-35-19-8-4-14(5-9-19)21-22(15-2-6-16(25)7-3-15)30(23(29-21)24(26,27)28)11-10-17(31)12-18(32)13-20(33)34/h2-9,17-18,31-32H,10-13H2,1H3,(H,33,34)/p-1/t17-,18-/m1/s1	FZKWMBYWWWNHAU-QZTJIDSGSA-M	50042602	CHEMBL120869::Sodium; 7-[5-(4-fluoro-phenyl)-4-(4-methoxy-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 68							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042602&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929224	103974191		CHEMBL120869			C03834	ZINC13833938	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067888	CC(C)c1nc(c(-c2cc(Cl)cc(Cl)c2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C25H25Cl2FN2O4/c1-14(2)25-29-23(15-3-5-19(28)6-4-15)24(16-9-17(26)11-18(27)10-16)30(25)8-7-20(31)12-21(32)13-22(33)34/h3-11,14,20-21,31-32H,12-13H2,1-2H3,(H,33,34)/p-1/b8-7+/t20-,21-/m1/s1	VQTQMORSAWEUGO-DVFFMCNPSA-M	50042603	(E)-(3R,5S)-7-[5-(3,5-Dichloro-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL332912::Sodium; 7-[5-(3,5-dichloro-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 22							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042603&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392531	103974192		CHEMBL332912			C03834	ZINC13833959	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067889	COc1ccc(cc1)-c1c(nc(n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(F)(F)F)-c1ccc(F)cc1	InChI=1S/C24H24F4N2O5/c1-35-19-8-4-15(5-9-19)22-21(14-2-6-16(25)7-3-14)29-23(24(26,27)28)30(22)11-10-17(31)12-18(32)13-20(33)34/h2-9,17-18,31-32H,10-13H2,1H3,(H,33,34)/p-1/t17-,18-/m1/s1	VCIUTFYLSDZDIB-QZTJIDSGSA-M	50042606	CHEMBL120971::Sodium; 7-[4-(4-fluoro-phenyl)-5-(4-methoxy-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 418							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042606&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929227	103974195		CHEMBL120971			C03834	ZINC13833948	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067890	Cc1cccc(c1)-c1nc(n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1)C(F)(F)F	InChI=1S/C24H24F4N2O4/c1-14-3-2-4-16(11-14)21-22(15-5-7-17(25)8-6-15)30(23(29-21)24(26,27)28)10-9-18(31)12-19(32)13-20(33)34/h2-8,11,18-19,31-32H,9-10,12-13H2,1H3,(H,33,34)/p-1/t18-,19-/m1/s1	AHWZEKXSJHDUBC-RTBURBONSA-M	50042604	CHEMBL120860::Sodium; 7-[5-(4-fluoro-phenyl)-4-m-tolyl-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 29							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042604	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042604&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929225	103974193		CHEMBL120860			C03834	ZINC13833934	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067891	O[C@H](CCn1c(nc(c1-c1ccc(F)cc1)-c1ccc(F)cc1)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C23H21F5N2O4/c24-15-5-1-13(2-6-15)20-21(14-3-7-16(25)8-4-14)30(22(29-20)23(26,27)28)10-9-17(31)11-18(32)12-19(33)34/h1-8,17-18,31-32H,9-12H2,(H,33,34)/p-1/t17-,18-/m1/s1	DVCRZEAXIZYEGO-QZTJIDSGSA-M	50042605	CHEMBL120908::Sodium; 7-[4,5-bis-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 38							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042605&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929226	103974194		CHEMBL120908			C03834	ZINC13833936	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067893	COc1cccc(c1)-c1nc(n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1)C(F)(F)F	InChI=1S/C24H24F4N2O5/c1-35-19-4-2-3-15(11-19)21-22(14-5-7-16(25)8-6-14)30(23(29-21)24(26,27)28)10-9-17(31)12-18(32)13-20(33)34/h2-8,11,17-18,31-32H,9-10,12-13H2,1H3,(H,33,34)/p-1/t17-,18-/m1/s1	NOZNYDCUAHKTNY-QZTJIDSGSA-M	50042608	CHEMBL431842::Sodium; 7-[5-(4-fluoro-phenyl)-4-(3-methoxy-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042608	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042608&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929228	103974197		CHEMBL431842			C03834	ZINC13833935	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067894	Cc1cc(cc(C)c1F)-c1nc(n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1)C(F)(F)F	InChI=1S/C25H25F5N2O4/c1-13-9-16(10-14(2)21(13)27)22-23(15-3-5-17(26)6-4-15)32(24(31-22)25(28,29)30)8-7-18(33)11-19(34)12-20(35)36/h3-6,9-10,18-19,33-34H,7-8,11-12H2,1-2H3,(H,35,36)/p-1/t18-,19-/m1/s1	BNJTUCRVQVPSJG-RTBURBONSA-M	50042610	CHEMBL332202::Sodium; 7-[4-(4-fluoro-3,5-dimethyl-phenyl)-5-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 32							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042610&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929230	103974199		CHEMBL332202			C03834	ZINC13833940	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067895	O[C@H](CCn1c(nc(c1-c1ccccc1)-c1ccc(F)cc1)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C23H22F4N2O4/c24-16-8-6-14(7-9-16)20-21(15-4-2-1-3-5-15)29(22(28-20)23(25,26)27)11-10-17(30)12-18(31)13-19(32)33/h1-9,17-18,30-31H,10-13H2,(H,32,33)/p-1/t17-,18-/m1/s1	UOJCQSIIQDWZRB-QZTJIDSGSA-M	50042609	CHEMBL331923::Sodium; 7-[4-(4-fluoro-phenyl)-5-phenyl-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 201							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042609	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042609&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929229	103974198		CHEMBL331923			C03834	ZINC13833943	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067896	CC(C)c1nc(c(-c2ccc(F)cc2C)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C26H28F2N2O4/c1-15(2)26-29-24(17-4-6-18(27)7-5-17)25(22-9-8-19(28)12-16(22)3)30(26)11-10-20(31)13-21(32)14-23(33)34/h4-12,15,20-21,31-32H,13-14H2,1-3H3,(H,33,34)/p-1/b11-10+/t20-,21-/m1/s1	OFLGDXCJEMRJRI-VRDGUJSXSA-M	50042612	CHEMBL121610::Sodium; 7-[5-(4-fluoro-2-methyl-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042612&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392478	103974201		CHEMBL121610			C03834	ZINC13833961	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067897	CC(C)c1nc(c(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccc(F)cc1	InChI=1S/C25H26F2N2O4/c1-15(2)25-28-23(16-3-7-18(26)8-4-16)24(17-5-9-19(27)10-6-17)29(25)12-11-20(30)13-21(31)14-22(32)33/h3-12,15,20-21,30-31H,13-14H2,1-2H3,(H,32,33)/b12-11+/t20-,21-/m1/s1	GQOQQDINYJTQDY-LKWCPCFXSA-N	50042607	(E)-(3R,5S)-7-[4,5-Bis-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::7-[4,5-Bis-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid::CHEMBL333760	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042607&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14849847	103974196		CHEMBL333760			C03834	ZINC01915719	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067898	O[C@H](CCn1c(nc(c1-c1ccc(cc1)C(F)(F)F)-c1ccc(F)cc1)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C24H21F7N2O4/c25-16-7-3-13(4-8-16)20-21(14-1-5-15(6-2-14)23(26,27)28)33(22(32-20)24(29,30)31)10-9-17(34)11-18(35)12-19(36)37/h1-8,17-18,34-35H,9-12H2,(H,36,37)/p-1/t17-,18-/m1/s1	WTYSQQGWHXWTHO-QZTJIDSGSA-M	50042613	CHEMBL333437::Sodium; 7-[4-(4-fluoro-phenyl)-2-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042613&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929232	103974202		CHEMBL333437			C03834	ZINC27189483	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067899	CC(C)c1nc(c(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1cc(C)c(Cl)c(C)c1	InChI=1S/C27H30ClFN2O4/c1-15(2)27-30-25(19-11-16(3)24(28)17(4)12-19)26(18-5-7-20(29)8-6-18)31(27)10-9-21(32)13-22(33)14-23(34)35/h5-12,15,21-22,32-33H,13-14H2,1-4H3,(H,34,35)/p-1/b10-9+/t21-,22-/m1/s1	JHWFCZWVPHDZDN-CXNSYNGHSA-M	50042615	(E)-(3R,5S)-7-[4-(4-Chloro-3,5-dimethyl-phenyl)-5-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL332201::Sodium; 7-[4-(4-chloro-3,5-dimethyl-phenyl)-5-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042615&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392513	103974204		CHEMBL332201			C03834	ZINC13833964	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067900	CC(C)(C)c1nc(c(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C26H28F2N2O4/c1-26(2,3)25-29-23(16-4-8-18(27)9-5-16)24(17-6-10-19(28)11-7-17)30(25)13-12-20(31)14-21(32)15-22(33)34/h4-13,20-21,31-32H,14-15H2,1-3H3,(H,33,34)/p-1/b13-12+/t20-,21-/m1/s1	FQBVOLSVMZUCCC-DDVDASKDSA-M	50042616	(E)-(3R,5S)-7-[2-tert-Butyl-4,5-bis-(4-fluoro-phenyl)-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL122957::Sodium; 7-[2-tert-butyl-4,5-bis-(4-fluoro-phenyl)-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042616&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392489	103974205		CHEMBL122957			C03834	ZINC13833955	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067901	CC(C)c1nc(c(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C25H26F2N2O4/c1-15(2)25-28-23(16-3-7-18(26)8-4-16)24(17-5-9-19(27)10-6-17)29(25)12-11-20(30)13-21(31)14-22(32)33/h3-12,15,20-21,30-31H,13-14H2,1-2H3,(H,32,33)/p-1/b12-11+/t20-,21-/m1/s1	GQOQQDINYJTQDY-LKWCPCFXSA-M	50042614	CHEMBL120932::Sodium; 7-[4,5-bis-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042614&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392458	103974203		CHEMBL120932			C03834		1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067902	O[C@H](CCn1c(nc(-c2cccs2)c1-c1ccc(F)cc1)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C21H20F4N2O4S/c22-13-5-3-12(4-6-13)19-18(16-2-1-9-32-16)26-20(21(23,24)25)27(19)8-7-14(28)10-15(29)11-17(30)31/h1-6,9,14-15,28-29H,7-8,10-11H2,(H,30,31)/p-1/t14-,15-/m1/s1	XEKOTAWIVRWWCM-HUUCEWRRSA-M	50042617	CHEMBL330995::Sodium; 7-[5-(4-fluoro-phenyl)-4-thiophen-2-yl-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 64							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042617&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929233	103974206		CHEMBL330995			C03834	ZINC13833941	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067903	O[C@H](CCn1c(nc(c1-c1ccc(F)cc1)-c1cccnc1)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C22H21F4N3O4/c23-15-5-3-13(4-6-15)20-19(14-2-1-8-27-12-14)28-21(22(24,25)26)29(20)9-7-16(30)10-17(31)11-18(32)33/h1-6,8,12,16-17,30-31H,7,9-11H2,(H,32,33)/p-1/t16-,17-/m1/s1	CWAJYFDESKFQJM-IAGOWNOFSA-M	50042619	CHEMBL420899::Sodium; 7-[5-(4-fluoro-phenyl)-4-pyridin-3-yl-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 66							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042619&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929235	103974208		CHEMBL420899			C03834	ZINC13833942	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067904	O[C@H](CCn1c(nc(c1-c1ccc(F)cc1)-c1ccccc1)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C23H22F4N2O4/c24-16-8-6-15(7-9-16)21-20(14-4-2-1-3-5-14)28-22(23(25,26)27)29(21)11-10-17(30)12-18(31)13-19(32)33/h1-9,17-18,30-31H,10-13H2,(H,32,33)/p-1/t17-,18-/m1/s1	XEOBJYNXZGKYDN-QZTJIDSGSA-M	50042618	CHEMBL121122::Sodium; 7-[5-(4-fluoro-phenyl)-4-phenyl-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 31							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042618&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929234	103974207		CHEMBL121122			C03834	ZINC13833932	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067905	CC(C)c1nc(c(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1cccc(c1)S(C)(=O)=O	InChI=1S/C26H29FN2O6S/c1-16(2)26-28-24(18-5-4-6-22(13-18)36(3,34)35)25(17-7-9-19(27)10-8-17)29(26)12-11-20(30)14-21(31)15-23(32)33/h4-13,16,20-21,30-31H,14-15H2,1-3H3,(H,32,33)/p-1/b12-11+/t20-,21-/m1/s1	VCWDRTWXFLVEDT-LKWCPCFXSA-M	50042620	(E)-(3R,5S)-7-[5-(4-Fluoro-phenyl)-2-isopropyl-4-(3-methanesulfonyl-phenyl)-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL331899::Sodium; 7-[5-(4-fluoro-phenyl)-2-isopropyl-4-(3-methanesulfonyl-phenyl)-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042620&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392462	103974209		CHEMBL331899			C03834	ZINC13833966	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067906	O[C@H](CCn1c(nc(c1-c1cccc(Cl)c1)-c1ccc(F)cc1)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C23H21ClF4N2O4/c24-15-3-1-2-14(10-15)21-20(13-4-6-16(25)7-5-13)29-22(23(26,27)28)30(21)9-8-17(31)11-18(32)12-19(33)34/h1-7,10,17-18,31-32H,8-9,11-12H2,(H,33,34)/p-1/t17-,18-/m1/s1	LBYCJGVDQHYTSA-QZTJIDSGSA-M	50042621	CHEMBL123253::Sodium; 7-[5-(3-chloro-phenyl)-4-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 41							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042621&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929236	103974210		CHEMBL123253			C03834	ZINC13833944	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067908	O[C@H](CCn1c(nc(c1-c1cccs1)-c1ccc(F)cc1)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C21H20F4N2O4S/c22-13-5-3-12(4-6-13)18-19(16-2-1-9-32-16)27(20(26-18)21(23,24)25)8-7-14(28)10-15(29)11-17(30)31/h1-6,9,14-15,28-29H,7-8,10-11H2,(H,30,31)/p-1/t14-,15-/m1/s1	AGSJSKWODIKPDY-HUUCEWRRSA-M	50042623	CHEMBL121052::Sodium; 7-[4-(4-fluoro-phenyl)-5-thiophen-2-yl-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 215							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042623&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929237	103974212		CHEMBL121052			C03834	ZINC13833951	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067909	CC(C)c1nc(c(-c2cc(C)c(F)c(C)c2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C27H30F2N2O4/c1-15(2)27-30-25(18-5-7-20(28)8-6-18)26(19-11-16(3)24(29)17(4)12-19)31(27)10-9-21(32)13-22(33)14-23(34)35/h5-12,15,21-22,32-33H,13-14H2,1-4H3,(H,34,35)/p-1/b10-9+/t21-,22-/m1/s1	LGOOFKNTNWQRMK-CXNSYNGHSA-M	50042624	(E)-(3R,5S)-7-[5-(4-Fluoro-3,5-dimethyl-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL121602::Sodium; 7-[5-(4-fluoro-3,5-dimethyl-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042624&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392494	103974213		CHEMBL121602			C03834	ZINC13833962	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067910	CNc1cccc(c1)-c1nc(C(C)C)n(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1	InChI=1S/C26H30FN3O4/c1-16(2)26-29-24(18-5-4-6-20(13-18)28-3)25(17-7-9-19(27)10-8-17)30(26)12-11-21(31)14-22(32)15-23(33)34/h4-13,16,21-22,28,31-32H,14-15H2,1-3H3,(H,33,34)/p-1/b12-11+/t21-,22-/m1/s1	ZPONNDMYVQEZAQ-CXYUPCIPSA-M	50042622	(E)-(3R,5S)-7-[5-(4-Fluoro-phenyl)-2-isopropyl-4-(3-methylamino-phenyl)-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL431659::Sodium; 7-[5-(4-fluoro-phenyl)-2-isopropyl-4-(3-methylamino-phenyl)-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042622&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392486	103974211		CHEMBL431659			C03834	ZINC34717643	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067911	O[C@H](CCn1c(nc(c1-c1cccnc1)-c1ccc(F)cc1)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C22H21F4N3O4/c23-15-5-3-13(4-6-15)19-20(14-2-1-8-27-12-14)29(21(28-19)22(24,25)26)9-7-16(30)10-17(31)11-18(32)33/h1-6,8,12,16-17,30-31H,7,9-11H2,(H,32,33)/p-1/t16-,17-/m1/s1	YLIOTEUATHEBPA-IAGOWNOFSA-M	50042627	CHEMBL123417::Sodium; 7-[4-(4-fluoro-phenyl)-5-pyridin-3-yl-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042627&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929238	103974216		CHEMBL123417			C03834	ZINC13833952	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067912	CC(C)c1c(nc(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C25H26F2N2O4/c1-15(2)24-23(16-3-7-18(26)8-4-16)28-25(17-5-9-19(27)10-6-17)29(24)12-11-20(30)13-21(31)14-22(32)33/h3-12,15,20-21,30-31H,13-14H2,1-2H3,(H,32,33)/p-1/b12-11+/t20-,21-/m1/s1	TVIKMEWXHYDWEQ-LKWCPCFXSA-M	50042625	(E)-(3R,5S)-7-[2,4-Bis-(4-fluoro-phenyl)-5-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL331048::Sodium; 7-[2,4-bis-(4-fluoro-phenyl)-5-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042625	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042625&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392511	103974214		CHEMBL331048			C03834	ZINC13833957	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067913	Cc1nc(c(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C23H22F2N2O4/c1-14-26-22(15-2-6-17(24)7-3-15)23(16-4-8-18(25)9-5-16)27(14)11-10-19(28)12-20(29)13-21(30)31/h2-11,19-20,28-29H,12-13H2,1H3,(H,30,31)/p-1/b11-10+/t19-,20-/m1/s1	BEKYROJJVQTUPM-ANMDKAQQSA-M	50042626	CHEMBL434224::Sodium; 7-[4,5-bis-(4-fluoro-phenyl)-2-methyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>100							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042626&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392474	103974215		CHEMBL434224			C03834	ZINC13833954	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067914	CC(C)c1nc(-c2ccccc2)n(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C25H27FN2O4/c1-16(2)24-22(13-12-20(29)14-21(30)15-23(31)32)28(19-10-8-18(26)9-11-19)25(27-24)17-6-4-3-5-7-17/h3-13,16,20-21,29-30H,14-15H2,1-2H3,(H,31,32)/p-1/b13-12+/t20-,21-/m1/s1	ZYZCALPXKGUGJI-DDVDASKDSA-M	50042629	CHEMBL121309::Sodium; 7-[3-(4-fluoro-phenyl)-5-isopropyl-2-phenyl-3H-imidazol-4-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.6							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042629&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947031	103974218		CHEMBL121309			C03834	ZINC13833970	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067915	CC(C)c1nc(c(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1cccnc1	InChI=1S/C24H26FN3O4/c1-15(2)24-27-22(17-4-3-10-26-14-17)23(16-5-7-18(25)8-6-16)28(24)11-9-19(29)12-20(30)13-21(31)32/h3-11,14-15,19-20,29-30H,12-13H2,1-2H3,(H,31,32)/p-1/b11-9+/t19-,20-/m1/s1	ALLUALRNIBGJAM-MBUYQLGJSA-M	50042631	(E)-(3R,5S)-7-[5-(4-Fluoro-phenyl)-2-isopropyl-4-pyridin-3-yl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL121727::Sodium; 7-[5-(4-fluoro-phenyl)-2-isopropyl-4-pyridin-3-yl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042631&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392528	103974220		CHEMBL121727			C03834	ZINC13833965	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067916	Cc1cccc(c1)-c1c(nc(n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(F)(F)F)-c1ccc(F)cc1	InChI=1S/C24H24F4N2O4/c1-14-3-2-4-16(11-14)22-21(15-5-7-17(25)8-6-15)29-23(24(26,27)28)30(22)10-9-18(31)12-19(32)13-20(33)34/h2-8,11,18-19,31-32H,9-10,12-13H2,1H3,(H,33,34)/p-1/t18-,19-/m1/s1	YFVBHTWNOFCOCY-RTBURBONSA-M	50042630	CHEMBL123487::Sodium; 7-[4-(4-fluoro-phenyl)-5-m-tolyl-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 74							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042630&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929239	103974219		CHEMBL123487			C03834	ZINC13833945	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067917	Cc1ccc(cc1)-c1nc(n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1)C(F)(F)F	InChI=1S/C24H24F4N2O4/c1-14-2-4-15(5-3-14)21-22(16-6-8-17(25)9-7-16)30(23(29-21)24(26,27)28)11-10-18(31)12-19(32)13-20(33)34/h2-9,18-19,31-32H,10-13H2,1H3,(H,33,34)/p-1/t18-,19-/m1/s1	SZDMFWDZIPEBPI-RTBURBONSA-M	50042635	CHEMBL123354::Sodium; 7-[5-(4-fluoro-phenyl)-4-p-tolyl-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 43							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042635&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929241	103974224		CHEMBL123354			C03834	ZINC13833937	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067918	COc1cccc(c1)-c1c(nc(n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(F)(F)F)-c1ccc(F)cc1	InChI=1S/C24H24F4N2O5/c1-35-19-4-2-3-15(11-19)22-21(14-5-7-16(25)8-6-14)29-23(24(26,27)28)30(22)10-9-17(31)12-18(32)13-20(33)34/h2-8,11,17-18,31-32H,9-10,12-13H2,1H3,(H,33,34)/p-1/t17-,18-/m1/s1	FTSUKTUNZNZOER-QZTJIDSGSA-M	50042632	CHEMBL332125::Sodium; 7-[4-(4-fluoro-phenyl)-5-(3-methoxy-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 135							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042632&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929240	103974221		CHEMBL332125			C03834	ZINC13833946	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067919	O[C@H](C[C@H](O)\C=C\n1c(nc(c1-c1ccc(F)cc1)-c1ccc(F)cc1)C(F)(F)F)CC([O-])=O	InChI=1S/C23H19F5N2O4/c24-15-5-1-13(2-6-15)20-21(14-3-7-16(25)8-4-14)30(22(29-20)23(26,27)28)10-9-17(31)11-18(32)12-19(33)34/h1-10,17-18,31-32H,11-12H2,(H,33,34)/p-1/b10-9+/t17-,18-/m1/s1	WQXDCZIGRVCRLY-AQRBRUGDSA-M	50042628	(E)-(3R,5S)-7-[4,5-Bis-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL333307::Sodium; 7-[4,5-bis-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042628&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392454	103974217		CHEMBL333307			C03834	ZINC13833953	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067920	Cc1ccc(cc1)-c1c(nc(n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(F)(F)F)-c1ccc(F)cc1	InChI=1S/C24H24F4N2O4/c1-14-2-4-16(5-3-14)22-21(15-6-8-17(25)9-7-15)29-23(24(26,27)28)30(22)11-10-18(31)12-19(32)13-20(33)34/h2-9,18-19,31-32H,10-13H2,1H3,(H,33,34)/p-1/t18-,19-/m1/s1	UEOJDEPGERHOSQ-RTBURBONSA-M	50042637	CHEMBL122713::Sodium; 7-[4-(4-fluoro-phenyl)-5-p-tolyl-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 750							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042637&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929243	103974226		CHEMBL122713			C03834	ZINC13833947	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067921	Cc1cc(C)cc(c1)-c1c(nc(n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(F)(F)F)-c1ccc(F)cc1	InChI=1S/C25H26F4N2O4/c1-14-9-15(2)11-17(10-14)23-22(16-3-5-18(26)6-4-16)30-24(25(27,28)29)31(23)8-7-19(32)12-20(33)13-21(34)35/h3-6,9-11,19-20,32-33H,7-8,12-13H2,1-2H3,(H,34,35)/p-1/t19-,20-/m1/s1	WNUNYQNGIDTXFY-WOJBJXKFSA-M	50042636	CHEMBL121230::Sodium; 7-[5-(3,5-dimethyl-phenyl)-4-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 38							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042636&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929242	103974225		CHEMBL121230			C03834	ZINC13833949	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067922	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@]12C	InChI=1S/C25H38O5/c1-6-16(3)24(28)30-22-12-15(2)11-18-8-7-17(4)21(25(18,22)5)10-9-20-13-19(26)14-23(27)29-20/h7-8,11,15-17,19-22,26H,6,9-10,12-14H2,1-5H3/t15-,16-,17-,19+,20+,21-,22-,25-/m0/s1	XVJCULXGMUEAHM-NBRVLZGDSA-N	50042601	2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7,8a-trimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL121756	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042601&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			7076302	103974190		CHEMBL121756				ZINC04026151	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067923	CC(C)c1nc(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C25H28F2N2O4/c1-15(2)25-28-23(16-3-7-18(26)8-4-16)24(17-5-9-19(27)10-6-17)29(25)12-11-20(30)13-21(31)14-22(32)33/h3-10,15,20-21,30-31H,11-14H2,1-2H3,(H,32,33)/p-1/t20-,21-/m1/s1	QTQCFDBJFMITBE-NHCUHLMSSA-M	50042639	CHEMBL331675::Sodium; 7-[4,5-bis-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 316							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042639&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929244	103974228		CHEMBL331675			C03834	ZINC11687392	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067924	CC(C)c1nc(c(-c2cc(C)cc(C)c2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C27H31FN2O4/c1-16(2)27-29-25(19-5-7-21(28)8-6-19)26(20-12-17(3)11-18(4)13-20)30(27)10-9-22(31)14-23(32)15-24(33)34/h5-13,16,22-23,31-32H,14-15H2,1-4H3,(H,33,34)/p-1/b10-9+/t22-,23-/m1/s1	LYUVRKOESGKHFS-GZURJRJYSA-M	50042638	(E)-(3R,5S)-7-[5-(3,5-Dimethyl-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL122725::Sodium; 7-[5-(3,5-dimethyl-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 56							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042638&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392461	103974227		CHEMBL122725			C03834	ZINC13833960	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067925	CN(C)c1nc(c(-c2ccc(F)cc2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C24H25F2N3O4/c1-28(2)24-27-22(15-3-7-17(25)8-4-15)23(16-5-9-18(26)10-6-16)29(24)12-11-19(30)13-20(31)14-21(32)33/h3-12,19-20,30-31H,13-14H2,1-2H3,(H,32,33)/p-1/b12-11+/t19-,20-/m1/s1	GVZUOJWJKSNJNR-XICOBVEKSA-M	50042634	(E)-(3R,5S)-7-[2-Dimethylamino-4,5-bis-(4-fluoro-phenyl)-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL123127::Sodium; 7-[2-dimethylamino-4,5-bis-(4-fluoro-phenyl)-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042634&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392501	103974223		CHEMBL123127			C03834	ZINC13833956	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067926	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CCC(O)C[C@H](O)CC([O-])=O)[C@@]12C	InChI=1S/C24H38O7/c1-5-14(2)23(30)31-21-12-18(26)10-16-7-6-15(3)20(24(16,21)4)9-8-17(25)11-19(27)13-22(28)29/h6-7,10,14-15,17-21,25-27H,5,8-9,11-13H2,1-4H3,(H,28,29)/p-1/t14-,15-,17?,18+,19-,20-,21-,24-/m0/s1	QJQBZYLPTCSSKN-HVYLIOLISA-M	50042611	CHEMBL333003::Sodium; 3,5-dihydroxy-7-[6-hydroxy-2,8a-dimethyl-8-(2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042611	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042611&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929231	103974200		CHEMBL333003			C03834	ZINC27186872	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067927	CCc1cc(cc(CC)c1F)-c1c(nc(C(C)C)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C29H34F2N2O4/c1-5-18-13-21(14-19(6-2)26(18)31)28-27(20-7-9-22(30)10-8-20)32-29(17(3)4)33(28)12-11-23(34)15-24(35)16-25(36)37/h7-14,17,23-24,34-35H,5-6,15-16H2,1-4H3,(H,36,37)/p-1/b12-11+/t23-,24-/m1/s1	SKSTXAOPQPZAAH-DLFHSDBESA-M	50042633	(E)-(3R,5S)-7-[5-(3,5-Diethyl-4-fluoro-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL330981::Sodium; 7-[5-(3,5-diethyl-4-fluoro-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042633&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392502	103974222		CHEMBL330981			C03834	ZINC13833963	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067928	O[C@H](CCn1c(nc(c1-c1ccc(F)cc1)-c1ccc(cc1)C(F)(F)F)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C24H21F7N2O4/c25-16-7-3-14(4-8-16)21-20(13-1-5-15(6-2-13)23(26,27)28)32-22(24(29,30)31)33(21)10-9-17(34)11-18(35)12-19(36)37/h1-8,17-18,34-35H,9-12H2,(H,36,37)/p-1/t17-,18-/m1/s1	NJYMJORRPOFUIH-QZTJIDSGSA-M	50042642	CHEMBL332244::Sodium; 7-[5-(4-fluoro-phenyl)-2-trifluoromethyl-4-(4-trifluoromethyl-phenyl)-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 200							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042642	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042642&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929247	103974231		CHEMBL332244			C03834	ZINC27198120	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067929	Cc1cc(C)cc(c1)-c1nc(n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1)C(F)(F)F	InChI=1S/C25H26F4N2O4/c1-14-9-15(2)11-17(10-14)22-23(16-3-5-18(26)6-4-16)31(24(30-22)25(27,28)29)8-7-19(32)12-20(33)13-21(34)35/h3-6,9-11,19-20,32-33H,7-8,12-13H2,1-2H3,(H,34,35)/p-1/t19-,20-/m1/s1	HQPXQLIRVAMCMS-WOJBJXKFSA-M	50042641	CHEMBL333479::Sodium; 7-[4-(3,5-dimethyl-phenyl)-5-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 24							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042641&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929246	103974230		CHEMBL333479			C03834	ZINC13833939	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067930	O[C@H](CCn1c(nc(c1-c1ccc(F)cc1)-c1cccc(Cl)c1)C(F)(F)F)C[C@@H](O)CC([O-])=O	InChI=1S/C23H21ClF4N2O4/c24-15-3-1-2-14(10-15)20-21(13-4-6-16(25)7-5-13)30(22(29-20)23(26,27)28)9-8-17(31)11-18(32)12-19(33)34/h1-7,10,17-18,31-32H,8-9,11-12H2,(H,33,34)/p-1/t17-,18-/m1/s1	CDOIXCGFLXAART-QZTJIDSGSA-M	50042640	CHEMBL332580::Sodium; 7-[4-(3-chloro-phenyl)-5-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 17							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042640	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042640&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929245	103974229		CHEMBL332580			C03834	ZINC13833933	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067931	Cc1cc(cc(C)c1F)-c1c(nc(n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(F)(F)F)-c1ccc(F)cc1	InChI=1S/C25H25F5N2O4/c1-13-9-16(10-14(2)21(13)27)23-22(15-3-5-17(26)6-4-15)31-24(25(28,29)30)32(23)8-7-18(33)11-19(34)12-20(35)36/h3-6,9-10,18-19,33-34H,7-8,11-12H2,1-2H3,(H,35,36)/p-1/t18-,19-/m1/s1	LTDYROUQOKRSJZ-RTBURBONSA-M	50042644	CHEMBL333717::Sodium; 7-[5-(4-fluoro-3,5-dimethyl-phenyl)-4-(4-fluoro-phenyl)-2-trifluoromethyl-imidazol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 31							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042644&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929248	103974233		CHEMBL333717			C03834	ZINC13833950	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067932	CC(C)c1nc(c(-c2cccc(Cl)c2)n1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C25H26ClFN2O4/c1-15(2)25-28-23(16-6-8-19(27)9-7-16)24(17-4-3-5-18(26)12-17)29(25)11-10-20(30)13-21(31)14-22(32)33/h3-12,15,20-21,30-31H,13-14H2,1-2H3,(H,32,33)/p-1/b11-10+/t20-,21-/m1/s1	FRHFGOPVPWQXEF-VRDGUJSXSA-M	50042643	(E)-(3R,5S)-7-[5-(3-Chloro-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL332797::Sodium; 7-[5-(3-chloro-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-imidazol-1-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8							ChEMBL	10.1021/jm00075a020	10.7270/Q2X929CH	8246233			Chan, C; Bailey, EJ; Hartley, CD; Hayman, DF; Hutson, JL; Inglis, GG; Jones, PS; Keeling, SE; Kirk, BE; Lamont, RB	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042643	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042643&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44392521	103974232		CHEMBL332797			C03834	ZINC13833958	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067933	COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(cc(c1-c1ccccc1)-c1ccc(F)cc1)C(C)C	InChI=1S/C27H30FNO4/c1-18(2)25-17-24(19-9-11-21(28)12-10-19)27(20-7-5-4-6-8-20)29(25)14-13-22(30)15-23(31)16-26(32)33-3/h4-14,17-18,22-23,30-31H,15-16H2,1-3H3/b14-13+/t22-,23-/m1/s1	AJOXEQVJSPASSZ-OKRGKCMKSA-N	50042645	7-[3-(4-Fluoro-phenyl)-5-isopropyl-2-phenyl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL332735	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042645	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042645&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44347242	103974234		CHEMBL332735				ZINC13833976	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067934	COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(cc(c1-c1ccc(F)cc1)-c1cccc(Cl)c1)C(C)C	InChI=1S/C27H29ClFNO4/c1-17(2)25-16-24(19-5-4-6-20(28)13-19)27(18-7-9-21(29)10-8-18)30(25)12-11-22(31)14-23(32)15-26(33)34-3/h4-13,16-17,22-23,31-32H,14-15H2,1-3H3/b12-11+/t22-,23-/m1/s1	XJJSLIQTCQSYFK-IJIRNXSHSA-N	50042646	7-[3-(3-Chloro-phenyl)-2-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL120922	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042646&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44347268	103974235		CHEMBL120922				ZINC13833973	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067935	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19?,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-KVVRZSONSA-N	50004774	(S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-((R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::(lovastatin)2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(mevinolin)::CHEMBL503	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004774&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6420024	103918321		CHEMBL503				ZINC04245664	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067936	COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(cc(c1-c1ccc(F)cc1)-c1ccncc1)C(C)C	InChI=1S/C26H29FN2O4/c1-17(2)24-16-23(18-8-11-28-12-9-18)26(19-4-6-20(27)7-5-19)29(24)13-10-21(30)14-22(31)15-25(32)33-3/h4-13,16-17,21-22,30-31H,14-15H2,1-3H3/b13-10+/t21-,22-/m1/s1	LJSUJSMDBKUUDU-SELKBFNUSA-N	50042647	7-[2-(4-Fluoro-phenyl)-5-isopropyl-3-pyridin-4-yl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL333904	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042647&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44347155	103974236		CHEMBL333904				ZINC13833974	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067937	COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(cc(c1-c1cccc(Br)c1)-c1ccc(F)cc1)C(C)C	InChI=1S/C27H29BrFNO4/c1-17(2)25-16-24(18-7-9-21(29)10-8-18)27(19-5-4-6-20(28)13-19)30(25)12-11-22(31)14-23(32)15-26(33)34-3/h4-13,16-17,22-23,31-32H,14-15H2,1-3H3/b12-11+/t22-,23-/m1/s1	XHNMVNVYJRNSAX-IJIRNXSHSA-N	50042649	7-[2-(3-Bromo-phenyl)-3-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL332205	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 69							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042649	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042649&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44347241	103974238		CHEMBL332205				ZINC27189752	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067938	CC[C@H](C)C(=O)O[C@H]1C[C@@H](O)C=C2C=C[C@H](C)[C@H](CCC(O)C[C@@H](O)CC([O-])=O)[C@@H]12	InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/p-1/t13-,14-,16?,17-,18+,19-,20-,22-/m0/s1	TUZYXOIXSAXUGO-IRJWOIIVSA-M	50006412	(3R,5R)-3,5-dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-((S)-2-methylbutanoyloxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoate sodium::3,5-dihydroxy-7-[8-hydroxy-3-methyl-10-[1-methyl-(1S)-propylcarbonyloxy]-(1R,2S,3S,8S,10S)-bicyclo[4.4.0]deca-4,6-dien-2-yl]-(3R,5R)-sodium heptanoate::CHEMBL690::CS-514::Eptastatin Sodium::PRAVASTATIN SODIUM::Pravachol::Pravastatin::SQ-31000::Sodium; (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-((S)-2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-heptanoate::Sodium; 3,5-dihydroxy-7-[6-hydroxy-2-methyl-8-(2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006412&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928735	103919832		CHEMBL690			C03834	ZINC26185904	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067939	COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(cc(c1-c1ccc(F)cc1)-c1ccccc1)C(C)C	InChI=1S/C27H30FNO4/c1-18(2)25-17-24(19-7-5-4-6-8-19)27(20-9-11-21(28)12-10-20)29(25)14-13-22(30)15-23(31)16-26(32)33-3/h4-14,17-18,22-23,30-31H,15-16H2,1-3H3/b14-13+/t22-,23-/m1/s1	VRAWTYAHHFBMEC-OKRGKCMKSA-N	50042650	7-[2-(4-Fluoro-phenyl)-5-isopropyl-3-phenyl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL121451	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042650&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44347269	103974239		CHEMBL121451				ZINC13833972	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067940	COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(cc(c1-c1cccc(Cl)c1)-c1ccc(F)cc1)C(C)C	InChI=1S/C27H29ClFNO4/c1-17(2)25-16-24(18-7-9-21(29)10-8-18)27(19-5-4-6-20(28)13-19)30(25)12-11-22(31)14-23(32)15-26(33)34-3/h4-13,16-17,22-23,31-32H,14-15H2,1-3H3/b12-11+/t22-,23-/m1/s1	RLGRHOYDEKEIMU-IJIRNXSHSA-N	50042651	7-[2-(3-Chloro-phenyl)-3-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL420893	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 71							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042651&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44347175	103974240		CHEMBL420893				ZINC13833977	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067941	COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(cc(c1-c1ccc(F)cc1)-c1cccc(Br)c1)C(C)C	InChI=1S/C27H29BrFNO4/c1-17(2)25-16-24(19-5-4-6-20(28)13-19)27(18-7-9-21(29)10-8-18)30(25)12-11-22(31)14-23(32)15-26(33)34-3/h4-13,16-17,22-23,31-32H,14-15H2,1-3H3/b12-11+/t22-,23-/m1/s1	DBEXGLZBTDQPGD-IJIRNXSHSA-N	50042654	7-[3-(3-Bromo-phenyl)-2-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL119609	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 0.500000							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042654&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44347267	103974243		CHEMBL119609				ZINC27186622	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067942	COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(cc(c1-c1ccc(F)cc1)-c1ccccn1)C(C)C	InChI=1S/C26H29FN2O4/c1-17(2)24-16-22(23-6-4-5-12-28-23)26(18-7-9-19(27)10-8-18)29(24)13-11-20(30)14-21(31)15-25(32)33-3/h4-13,16-17,20-21,30-31H,14-15H2,1-3H3/b13-11+/t20-,21-/m1/s1	WDSUHJDFSGRQSL-NGSBPTJYSA-N	50042652	7-[2-(4-Fluoro-phenyl)-5-isopropyl-3-pyridin-2-yl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL331680	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042652	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042652&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44347253	103974241		CHEMBL331680				ZINC13833975	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067943	COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(C(C)C)c(Br)c(c1-c1ccc(F)cc1)-c1ccc(F)cc1	InChI=1S/C27H28BrF2NO4/c1-16(2)26-25(28)24(17-4-8-19(29)9-5-17)27(18-6-10-20(30)11-7-18)31(26)13-12-21(32)14-22(33)15-23(34)35-3/h4-13,16,21-22,32-33H,14-15H2,1-3H3/b13-12+/t21-,22-/m1/s1	MUTCAPXLKRYEPR-ITWZMISCSA-N	50042653	7-[3-Bromo-4,5-bis-(4-fluoro-phenyl)-2-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL445123	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 0.300000							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042653&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			9937377	103974242		CHEMBL445123		2956		ZINC01537859	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067944	COC(=O)C[C@H](O)C[C@H](O)CCn1c(cc(c1-c1ccc(F)cc1)-c1ccc(F)cc1)C(C)C	InChI=1S/C27H31F2NO4/c1-17(2)25-16-24(18-4-8-20(28)9-5-18)27(19-6-10-21(29)11-7-19)30(25)13-12-22(31)14-23(32)15-26(33)34-3/h4-11,16-17,22-23,31-32H,12-15H2,1-3H3/t22-,23-/m1/s1	IKPHYCNGCCFKRG-DHIUTWEWSA-N	50042655	7-[2,3-Bis-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid methyl ester::CHEMBL121541	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 105							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042655&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			14968187	103974244		CHEMBL121541				ZINC13833978	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50067945	COC(=O)C[C@H](O)C[C@H](O)\C=C\n1c(cc(c1-c1ccc(F)cc1)-c1ccc(F)cc1)C(C)C	InChI=1S/C27H29F2NO4/c1-17(2)25-16-24(18-4-8-20(28)9-5-18)27(19-6-10-21(29)11-7-19)30(25)13-12-22(31)14-23(32)15-26(33)34-3/h4-13,16-17,22-23,31-32H,14-15H2,1-3H3/b13-12+/t22-,23-/m1/s1	WCGVTMHGMJNURR-GOHHFNLLSA-N	50042656	7-[2,3-Bis-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-hept-6-enoic acid methyl ester::CHEMBL333642	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2							ChEMBL	10.1021/jm00075a021	10.7270/Q2SJ1JP7	8246234			Procopiou, PA; Draper, CD; Hutson, JL; Inglis, GG; Ross, BC; Watson, NS	Glaxo Group Research Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042656	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042656&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44347189	103974245		CHEMBL333642				ZINC13833971	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089152	CC(CCc1ccc(cc1)-c1ccccc1)CC(O)=O	InChI=1S/C18H20O2/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	MDEHFNXAMDVESV-UHFFFAOYSA-N	50009725	CHEMBL3246892	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009725&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			151102	103922707		CHEMBL3246892				ZINC43307888	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089153	CC(CCc1ccc(cc1)-c1ccccc1)CC(O)=O	InChI=1S/C18H20O2/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	MDEHFNXAMDVESV-UHFFFAOYSA-N	50009725	CHEMBL3246892	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009725&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			151102	103922707		CHEMBL3246892				ZINC43307888	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089156	CC(CCc1ccc(cc1)-c1ccccc1)CC(O)=O	InChI=1S/C18H20O2/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	MDEHFNXAMDVESV-UHFFFAOYSA-N	50009725	CHEMBL3246892	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 80000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009725&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			151102	103922707		CHEMBL3246892				ZINC43307888	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089158	CC(CC(O)=O)CC(=O)c1ccc(cc1)-c1ccccc1	InChI=1S/C18H18O3/c1-13(12-18(20)21)11-17(19)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10,13H,11-12H2,1H3,(H,20,21)	AFGNBPYPCPUOEN-UHFFFAOYSA-N	50009726	CHEMBL3246893	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 70000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009726&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13695064	103922708		CHEMBL3246893				ZINC43308024	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089159	CC(CC(O)=O)CC(=O)c1ccc(cc1)-c1ccccc1	InChI=1S/C18H18O3/c1-13(12-18(20)21)11-17(19)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10,13H,11-12H2,1H3,(H,20,21)	AFGNBPYPCPUOEN-UHFFFAOYSA-N	50009726	CHEMBL3246893	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 180000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009726&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13695064	103922708		CHEMBL3246893				ZINC43308024	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089161	CC(CC(O)=O)CC(=O)c1ccc(cc1)-c1ccccc1	InChI=1S/C18H18O3/c1-13(12-18(20)21)11-17(19)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10,13H,11-12H2,1H3,(H,20,21)	AFGNBPYPCPUOEN-UHFFFAOYSA-N	50009726	CHEMBL3246893	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1200000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009726&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13695064	103922708		CHEMBL3246893				ZINC43308024	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089164	CC(CC(O)=O)CC(=O)c1ccc(Oc2ccccc2)cc1	InChI=1S/C18H18O4/c1-13(12-18(20)21)11-17(19)14-7-9-16(10-8-14)22-15-5-3-2-4-6-15/h2-10,13H,11-12H2,1H3,(H,20,21)	BYAXTGWBVNYXRF-UHFFFAOYSA-N	50009727	CHEMBL3246894	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 290000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009727&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24727209	103922709		CHEMBL3246894				ZINC43307818	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089166	CC(CC(O)=O)CC(=O)c1ccc(Oc2ccccc2)cc1	InChI=1S/C18H18O4/c1-13(12-18(20)21)11-17(19)14-7-9-16(10-8-14)22-15-5-3-2-4-6-15/h2-10,13H,11-12H2,1H3,(H,20,21)	BYAXTGWBVNYXRF-UHFFFAOYSA-N	50009727	CHEMBL3246894	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 850000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009727&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24727209	103922709		CHEMBL3246894				ZINC43307818	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089168	CC(CC(O)=O)CC(=O)c1ccc(Oc2ccccc2)cc1	InChI=1S/C18H18O4/c1-13(12-18(20)21)11-17(19)14-7-9-16(10-8-14)22-15-5-3-2-4-6-15/h2-10,13H,11-12H2,1H3,(H,20,21)	BYAXTGWBVNYXRF-UHFFFAOYSA-N	50009727	CHEMBL3246894	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2100000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009727&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24727209	103922709		CHEMBL3246894				ZINC43307818	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089170	CC(CC(O)=O)CC(=O)c1ccc(Sc2ccccc2)cc1	InChI=1S/C18H18O3S/c1-13(12-18(20)21)11-17(19)14-7-9-16(10-8-14)22-15-5-3-2-4-6-15/h2-10,13H,11-12H2,1H3,(H,20,21)	BEGXNYDLAPCBGR-UHFFFAOYSA-N	50009728	CHEMBL3246895	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 240000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009728&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655689	103922710		CHEMBL3246895				ZINC44247212	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089172	CC(CC(O)=O)CC(=O)c1ccc(Sc2ccccc2)cc1	InChI=1S/C18H18O3S/c1-13(12-18(20)21)11-17(19)14-7-9-16(10-8-14)22-15-5-3-2-4-6-15/h2-10,13H,11-12H2,1H3,(H,20,21)	BEGXNYDLAPCBGR-UHFFFAOYSA-N	50009728	CHEMBL3246895	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 570000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009728&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655689	103922710		CHEMBL3246895				ZINC44247212	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089175	CC(CC(O)=O)CC(=O)c1ccc(Sc2ccccc2)cc1	InChI=1S/C18H18O3S/c1-13(12-18(20)21)11-17(19)14-7-9-16(10-8-14)22-15-5-3-2-4-6-15/h2-10,13H,11-12H2,1H3,(H,20,21)	BEGXNYDLAPCBGR-UHFFFAOYSA-N	50009728	CHEMBL3246895	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 780000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009728&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655689	103922710		CHEMBL3246895				ZINC44247212	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089183	CC(CC(O)=O)CC(=O)c1ccc2oc3ccccc3c2c1	InChI=1S/C18H16O4/c1-11(9-18(20)21)8-15(19)12-6-7-17-14(10-12)13-4-2-3-5-16(13)22-17/h2-7,10-11H,8-9H2,1H3,(H,20,21)	SHTVYDGUNFONHA-UHFFFAOYSA-N	50009729	CHEMBL3246896	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 110000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009729&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655690	103922711		CHEMBL3246896				ZINC43307698	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089186	CC(CC(O)=O)CC(=O)c1ccc2oc3ccccc3c2c1	InChI=1S/C18H16O4/c1-11(9-18(20)21)8-15(19)12-6-7-17-14(10-12)13-4-2-3-5-16(13)22-17/h2-7,10-11H,8-9H2,1H3,(H,20,21)	SHTVYDGUNFONHA-UHFFFAOYSA-N	50009729	CHEMBL3246896	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 260000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009729&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655690	103922711		CHEMBL3246896				ZINC43307698	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089191	CC(CC(O)=O)CC(=O)c1ccc2oc3ccccc3c2c1	InChI=1S/C18H16O4/c1-11(9-18(20)21)8-15(19)12-6-7-17-14(10-12)13-4-2-3-5-16(13)22-17/h2-7,10-11H,8-9H2,1H3,(H,20,21)	SHTVYDGUNFONHA-UHFFFAOYSA-N	50009729	CHEMBL3246896	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 430000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009729&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655690	103922711		CHEMBL3246896				ZINC43307698	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089193	CC(CC(O)=O)CC(=O)c1ccc2sc3ccccc3c2c1	InChI=1S/C18H16O3S/c1-11(9-18(20)21)8-15(19)12-6-7-17-14(10-12)13-4-2-3-5-16(13)22-17/h2-7,10-11H,8-9H2,1H3,(H,20,21)	PEMQXYUJEQLZMT-UHFFFAOYSA-N	50009731	CHEMBL3246897	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 160000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009731&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655691	103922713		CHEMBL3246897				ZINC43328048	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089197	CC(CC(O)=O)CC(=O)c1ccc2sc3ccccc3c2c1	InChI=1S/C18H16O3S/c1-11(9-18(20)21)8-15(19)12-6-7-17-14(10-12)13-4-2-3-5-16(13)22-17/h2-7,10-11H,8-9H2,1H3,(H,20,21)	PEMQXYUJEQLZMT-UHFFFAOYSA-N	50009731	CHEMBL3246897	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 310000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009731&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655691	103922713		CHEMBL3246897				ZINC43328048	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089198	CC(CC(O)=O)CC(=O)c1ccc2sc3ccccc3c2c1	InChI=1S/C18H16O3S/c1-11(9-18(20)21)8-15(19)12-6-7-17-14(10-12)13-4-2-3-5-16(13)22-17/h2-7,10-11H,8-9H2,1H3,(H,20,21)	PEMQXYUJEQLZMT-UHFFFAOYSA-N	50009731	CHEMBL3246897	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 930000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009731&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655691	103922713		CHEMBL3246897				ZINC43328048	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089199	CC(CC(O)=O)CC(=O)c1ccc2CCc3ccccc3-c2c1	InChI=1S/C20H20O3/c1-13(11-20(22)23)10-19(21)16-9-8-15-7-6-14-4-2-3-5-17(14)18(15)12-16/h2-5,8-9,12-13H,6-7,10-11H2,1H3,(H,22,23)	JRLIQKXFWMIXKO-UHFFFAOYSA-N	50009732	CHEMBL3246898	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009732&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655692	103922714		CHEMBL3246898				ZINC14243638	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089200	CC(CC(O)=O)CC(=O)c1ccc2CCc3ccccc3-c2c1	InChI=1S/C20H20O3/c1-13(11-20(22)23)10-19(21)16-9-8-15-7-6-14-4-2-3-5-17(14)18(15)12-16/h2-5,8-9,12-13H,6-7,10-11H2,1H3,(H,22,23)	JRLIQKXFWMIXKO-UHFFFAOYSA-N	50009732	CHEMBL3246898	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 60000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009732&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655692	103922714		CHEMBL3246898				ZINC14243638	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089202	CC(CC(O)=O)CC(=O)c1ccc2CCc3ccccc3-c2c1	InChI=1S/C20H20O3/c1-13(11-20(22)23)10-19(21)16-9-8-15-7-6-14-4-2-3-5-17(14)18(15)12-16/h2-5,8-9,12-13H,6-7,10-11H2,1H3,(H,22,23)	JRLIQKXFWMIXKO-UHFFFAOYSA-N	50009732	CHEMBL3246898	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 90000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009732&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655692	103922714		CHEMBL3246898				ZINC14243638	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089203	CC(CCc1ccc(Oc2ccccc2)cc1)CC(O)=O	InChI=1S/C18H20O3/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)21-16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	QWUMUTSCDRSNSH-UHFFFAOYSA-N	50009733	CHEMBL3246899	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009733	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009733&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			63534640	103922715		CHEMBL3246899				ZINC43834838	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089206	CC(CCc1ccc(Oc2ccccc2)cc1)CC(O)=O	InChI=1S/C18H20O3/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)21-16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	QWUMUTSCDRSNSH-UHFFFAOYSA-N	50009733	CHEMBL3246899	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009733	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009733&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			63534640	103922715		CHEMBL3246899				ZINC43834838	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089214	CC(CCc1ccc(Oc2ccccc2)cc1)CC(O)=O	InChI=1S/C18H20O3/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)21-16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	QWUMUTSCDRSNSH-UHFFFAOYSA-N	50009733	CHEMBL3246899	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 80000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009733	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009733&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			63534640	103922715		CHEMBL3246899				ZINC43834838	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089216	CC(CCc1ccc(Sc2ccccc2)cc1)CC(O)=O	InChI=1S/C18H20O2S/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)21-16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	UOKIBTZACZPMEH-UHFFFAOYSA-N	50009734	CHEMBL3246900	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009734&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655693	103922716		CHEMBL3246900				ZINC43327997	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089220	CC(CCc1ccc(Sc2ccccc2)cc1)CC(O)=O	InChI=1S/C18H20O2S/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)21-16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	UOKIBTZACZPMEH-UHFFFAOYSA-N	50009734	CHEMBL3246900	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 40000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009734&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655693	103922716		CHEMBL3246900				ZINC43327997	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089222	CC(CCc1ccc(Sc2ccccc2)cc1)CC(O)=O	InChI=1S/C18H20O2S/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)21-16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	UOKIBTZACZPMEH-UHFFFAOYSA-N	50009734	CHEMBL3246900	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009734&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655693	103922716		CHEMBL3246900				ZINC43327997	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089225	CC(CCc1ccc(cc1)S(=O)(=O)c1ccccc1)CC(O)=O	InChI=1S/C18H20O4S/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)23(21,22)16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	CEMQIVCALCGZGZ-UHFFFAOYSA-N	50009735	CHEMBL3246901	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 40000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009735&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			53716947	103922717		CHEMBL3246901				ZINC43307658	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089227	CC(CCc1ccc(cc1)S(=O)(=O)c1ccccc1)CC(O)=O	InChI=1S/C18H20O4S/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)23(21,22)16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	CEMQIVCALCGZGZ-UHFFFAOYSA-N	50009735	CHEMBL3246901	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 70000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009735&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			53716947	103922717		CHEMBL3246901				ZINC43307658	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089228	CC(CCc1ccc(cc1)S(=O)(=O)c1ccccc1)CC(O)=O	InChI=1S/C18H20O4S/c1-14(13-18(19)20)7-8-15-9-11-17(12-10-15)23(21,22)16-5-3-2-4-6-16/h2-6,9-12,14H,7-8,13H2,1H3,(H,19,20)	CEMQIVCALCGZGZ-UHFFFAOYSA-N	50009735	CHEMBL3246901	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 80000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009735&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			53716947	103922717		CHEMBL3246901				ZINC43307658	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089229	CC(CCc1ccc2oc3ccccc3c2c1)CC(O)=O	InChI=1S/C18H18O3/c1-12(10-18(19)20)6-7-13-8-9-17-15(11-13)14-4-2-3-5-16(14)21-17/h2-5,8-9,11-12H,6-7,10H2,1H3,(H,19,20)	IQIKCWCRXUZOGZ-UHFFFAOYSA-N	50009736	CHEMBL3246902	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 360000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009736	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009736&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			63535490	103922718		CHEMBL3246902				ZINC43328015	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089231	CC(CCc1ccc2oc3ccccc3c2c1)CC(O)=O	InChI=1S/C18H18O3/c1-12(10-18(19)20)6-7-13-8-9-17-15(11-13)14-4-2-3-5-16(14)21-17/h2-5,8-9,11-12H,6-7,10H2,1H3,(H,19,20)	IQIKCWCRXUZOGZ-UHFFFAOYSA-N	50009736	CHEMBL3246902	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 810000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009736	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009736&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			63535490	103922718		CHEMBL3246902				ZINC43328015	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089232	CC(CCc1ccc2oc3ccccc3c2c1)CC(O)=O	InChI=1S/C18H18O3/c1-12(10-18(19)20)6-7-13-8-9-17-15(11-13)14-4-2-3-5-16(14)21-17/h2-5,8-9,11-12H,6-7,10H2,1H3,(H,19,20)	IQIKCWCRXUZOGZ-UHFFFAOYSA-N	50009736	CHEMBL3246902	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1600000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009736	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009736&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			63535490	103922718		CHEMBL3246902				ZINC43328015	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089234	CC(CCc1ccc2sc3ccccc3c2c1)CC(O)=O	InChI=1S/C18H18O2S/c1-12(10-18(19)20)6-7-13-8-9-17-15(11-13)14-4-2-3-5-16(14)21-17/h2-5,8-9,11-12H,6-7,10H2,1H3,(H,19,20)	DLFAAEWKWPAVLO-UHFFFAOYSA-N	50009737	CHEMBL3246903	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 70000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009737&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655694	103922719		CHEMBL3246903				ZINC43834310	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089236	CC(CCc1ccc2sc3ccccc3c2c1)CC(O)=O	InChI=1S/C18H18O2S/c1-12(10-18(19)20)6-7-13-8-9-17-15(11-13)14-4-2-3-5-16(14)21-17/h2-5,8-9,11-12H,6-7,10H2,1H3,(H,19,20)	DLFAAEWKWPAVLO-UHFFFAOYSA-N	50009737	CHEMBL3246903	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 190000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009737&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655694	103922719		CHEMBL3246903				ZINC43834310	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089238	CC(CCc1ccc2sc3ccccc3c2c1)CC(O)=O	InChI=1S/C18H18O2S/c1-12(10-18(19)20)6-7-13-8-9-17-15(11-13)14-4-2-3-5-16(14)21-17/h2-5,8-9,11-12H,6-7,10H2,1H3,(H,19,20)	DLFAAEWKWPAVLO-UHFFFAOYSA-N	50009737	CHEMBL3246903	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 860000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009737&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655694	103922719		CHEMBL3246903				ZINC43834310	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089240	CC(CCc1ccc2c(c1)-c1ccccc1S2(=O)=O)CC(O)=O	InChI=1S/C18H18O4S/c1-12(10-18(19)20)6-7-13-8-9-17-15(11-13)14-4-2-3-5-16(14)23(17,21)22/h2-5,8-9,11-12H,6-7,10H2,1H3,(H,19,20)	ZTYCTUXGWFRNDY-UHFFFAOYSA-N	50009738	CHEMBL3246904	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009738&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655695	103922720		CHEMBL3246904				ZINC43307694	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089248	CC(CCc1ccc2c(c1)-c1ccccc1S2(=O)=O)CC(O)=O	InChI=1S/C18H18O4S/c1-12(10-18(19)20)6-7-13-8-9-17-15(11-13)14-4-2-3-5-16(14)23(17,21)22/h2-5,8-9,11-12H,6-7,10H2,1H3,(H,19,20)	ZTYCTUXGWFRNDY-UHFFFAOYSA-N	50009738	CHEMBL3246904	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 50000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009738&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655695	103922720		CHEMBL3246904				ZINC43307694	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089275	CC(CCc1ccc2CCc3ccccc3-c2c1)CC(O)=O	InChI=1S/C20H22O2/c1-14(12-20(21)22)6-7-15-8-9-17-11-10-16-4-2-3-5-18(16)19(17)13-15/h2-5,8-9,13-14H,6-7,10-12H2,1H3,(H,21,22)	LWHYQVFAHZASJH-UHFFFAOYSA-N	50009739	CHEMBL3246905	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009739&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655696	103922721		CHEMBL3246905				ZINC43307739	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089276	CC(CCc1ccc2CCc3ccccc3-c2c1)CC(O)=O	InChI=1S/C20H22O2/c1-14(12-20(21)22)6-7-15-8-9-17-11-10-16-4-2-3-5-18(16)19(17)13-15/h2-5,8-9,13-14H,6-7,10-12H2,1H3,(H,21,22)	LWHYQVFAHZASJH-UHFFFAOYSA-N	50009739	CHEMBL3246905	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009739&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655696	103922721		CHEMBL3246905				ZINC43307739	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089277	CC(CCc1ccc2CCc3ccccc3-c2c1)CC(O)=O	InChI=1S/C20H22O2/c1-14(12-20(21)22)6-7-15-8-9-17-11-10-16-4-2-3-5-18(16)19(17)13-15/h2-5,8-9,13-14H,6-7,10-12H2,1H3,(H,21,22)	LWHYQVFAHZASJH-UHFFFAOYSA-N	50009739	CHEMBL3246905	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 270000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009739&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655696	103922721		CHEMBL3246905				ZINC43307739	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089278	CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1	InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3	KNHUKKLJHYUCFP-UHFFFAOYSA-N	50085047	2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester::2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester::CHEMBL565::Clofibrate::EPIB::ETHYL CLOFIBRATE::Ethyl 2-(p-chlorophenoxy)isobutyrate::Ethyl chlorophenoxyisobutyrate::Liprin::alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester::alpha-p-Chlorophenoxyisobutyryl ethyl ester::ethyl 2-(4-chlorophenoxy)-2-methylpropanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 440000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085047&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			2796	103984530	3750	CHEMBL565	DB00636	2667	C06916	ZINC00056648	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089279	CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1	InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3	KNHUKKLJHYUCFP-UHFFFAOYSA-N	50085047	2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester::2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester::CHEMBL565::Clofibrate::EPIB::ETHYL CLOFIBRATE::Ethyl 2-(p-chlorophenoxy)isobutyrate::Ethyl chlorophenoxyisobutyrate::Liprin::alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester::alpha-p-Chlorophenoxyisobutyryl ethyl ester::ethyl 2-(4-chlorophenoxy)-2-methylpropanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 630000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085047&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			2796	103984530	3750	CHEMBL565	DB00636	2667	C06916	ZINC00056648	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089280	CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1	InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3	KNHUKKLJHYUCFP-UHFFFAOYSA-N	50085047	2-(4-Chlorophenoxy)-2-methylpropanoic acid ethyl ester::2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester::CHEMBL565::Clofibrate::EPIB::ETHYL CLOFIBRATE::Ethyl 2-(p-chlorophenoxy)isobutyrate::Ethyl chlorophenoxyisobutyrate::Liprin::alpha-(p-Chlorophenoxy)isobutyric acid, ethyl ester::alpha-p-Chlorophenoxyisobutyryl ethyl ester::ethyl 2-(4-chlorophenoxy)-2-methylpropanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 860000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085047&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			2796	103984530	3750	CHEMBL565	DB00636	2667	C06916	ZINC00056648	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50089256	CC(CCc1ccc2c(c1)-c1ccccc1S2(=O)=O)CC(O)=O	InChI=1S/C18H18O4S/c1-12(10-18(19)20)6-7-13-8-9-17-15(11-13)14-4-2-3-5-16(14)23(17,21)22/h2-5,8-9,11-12H,6-7,10H2,1H3,(H,19,20)	ZTYCTUXGWFRNDY-UHFFFAOYSA-N	50009738	CHEMBL3246904	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 80000							ChEMBL	10.1021/jm00222a039	10.7270/Q2GH9KGV	592342			Dygos, JH; Jett, CM; Chinn, LJ; Miller, JE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50009738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50009738&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			90655695	103922720		CHEMBL3246904				ZINC43307694	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50181018	CC[C@H](C)C(=O)O[C@H]1C[C@@H](O)C=C2C=C[C@H](C)[C@H](CCC(O)C[C@@H](O)CC([O-])=O)[C@@H]12	InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/p-1/t13-,14-,16?,17-,18+,19-,20-,22-/m0/s1	TUZYXOIXSAXUGO-IRJWOIIVSA-M	50006412	(3R,5R)-3,5-dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-((S)-2-methylbutanoyloxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoate sodium::3,5-dihydroxy-7-[8-hydroxy-3-methyl-10-[1-methyl-(1S)-propylcarbonyloxy]-(1R,2S,3S,8S,10S)-bicyclo[4.4.0]deca-4,6-dien-2-yl]-(3R,5R)-sodium heptanoate::CHEMBL690::CS-514::Eptastatin Sodium::PRAVASTATIN SODIUM::Pravachol::Pravastatin::SQ-31000::Sodium; (3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-((S)-2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-heptanoate::Sodium; 3,5-dihydroxy-7-[6-hydroxy-2-methyl-8-(2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.2							ChEMBL	10.1016/s0960-894x(01)00203-7	10.7270/Q26D5S8M	11392538			Suzuki, M; Iwasaki, H; Fujikawa, Y; Sakashita, M; Kitahara, M; Sakoda, R	Central Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50006412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50006412&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928735	103919832		CHEMBL690			C03834	ZINC26185904	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50034864	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus	 1.4								ChEMBL	10.1021/jm00393a030	10.7270/Q2TX3DCD	3656359			Heathcock, CH; Hadley, CR; Rosen, T; Theisen, PD; Hecker, SJ	University of California	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408609	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)N(C)Cc1ccccc1	InChI=1S/C34H39FN2O6S/c1-23(2)32-34(44(42,43)36(3)22-24-10-6-4-7-11-24)31(25-12-8-5-9-13-25)33(26-14-16-27(35)17-15-26)37(32)19-18-28(38)20-29(39)21-30(40)41/h4-17,23,28-29,38-39H,18-22H2,1-3H3,(H,40,41)/p-1/t28-,29-/m1/s1	AQOMJINFEWKPKT-FQLXRVMXSA-M	50231023	CHEMBL403430::sodium; (3R,5R)-7-[3-(benzyl-methyl-sulfamoyl)-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8.5							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231023	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231023&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			58914831	104054952		CHEMBL403430			C03834	ZINC29037740	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408610	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)N1CCN(C)CC1	InChI=1S/C31H40FN3O6S/c1-21(2)29-31(42(40,41)34-17-15-33(3)16-18-34)28(22-7-5-4-6-8-22)30(23-9-11-24(32)12-10-23)35(29)14-13-25(36)19-26(37)20-27(38)39/h4-12,21,25-26,36-37H,13-20H2,1-3H3,(H,38,39)/p-1/t25-,26-/m1/s1	NQPKWFHCRRXCBX-CLJLJLNGSA-M	50231019	CHEMBL402622::sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-(4-methylpiperazin-1-ylsulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.7							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231019&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935515	104054948		CHEMBL402622			C03834	ZINC29037723	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408611	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)N1CCc2ccccc2C1	InChI=1S/C35H38F2N2O6S/c1-22(2)33-35(46(44,45)38-17-15-23-5-3-4-6-26(23)21-38)32(24-7-11-27(36)12-8-24)34(25-9-13-28(37)14-10-25)39(33)18-16-29(40)19-30(41)20-31(42)43/h3-14,22,29-30,40-41H,15-21H2,1-2H3,(H,42,43)/p-1/t29-,30-/m1/s1	STBNWPSJTYYOOA-LOYHVIPDSA-M	50231025	CHEMBL251863::sodium (3R,5R)-7-(3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)-4,5-bis(4-fluorophenyl)-2-isopropyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8.4							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231025	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231025&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935518	104054954		CHEMBL251863			C03834	ZINC29037737	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408612	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC(O)=O)-c1ccccc1	InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1	XUKUURHRXDUEBC-KAYWLYCHSA-N	22164	(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid::(3R,5R)-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid::Atorvastatin::CHEMBL1487::CI 981::Lipitor::US9353061, Atorvastatina	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.8							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=22164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=22164&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	117	1HWK	60823	49845979	39548	CHEMBL1487		2949	C06834	ZINC03920719	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408613	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)Nc1ccc(cc1)S(N)(=O)=O	InChI=1S/C32H35F2N3O8S2/c1-19(2)30-32(47(44,45)36-24-11-13-27(14-12-24)46(35,42)43)29(20-3-7-22(33)8-4-20)31(21-5-9-23(34)10-6-21)37(30)16-15-25(38)17-26(39)18-28(40)41/h3-14,19,25-26,36,38-39H,15-18H2,1-2H3,(H,40,41)(H2,35,42,43)/p-1/t25-,26-/m1/s1	XVDTXKNUSWJVBR-CLJLJLNGSA-M	50231026	CHEMBL253258::sodium; (3R,5R)-7-[2,3-bis-(4-fluoro-phenyl)-5-isopropyl-4-(4-sulfamoyl-phenylsulfamoyl)-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.9							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231026	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231026&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935519	104054955		CHEMBL253258			C03834	ZINC29037733	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408614	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)N1CCCC1	InChI=1S/C30H37FN2O6S/c1-20(2)28-30(40(38,39)32-15-6-7-16-32)27(21-8-4-3-5-9-21)29(22-10-12-23(31)13-11-22)33(28)17-14-24(34)18-25(35)19-26(36)37/h3-5,8-13,20,24-25,34-35H,6-7,14-19H2,1-2H3,(H,36,37)/p-1/t24-,25-/m1/s1	BSBVKEVELKNWKN-JWQCQUIFSA-M	50231028	CHEMBL429487::sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(pyrrolidin-1-ylsulfonyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.6							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231028&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935521	104054957		CHEMBL429487			C03834	ZINC29037711	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408615	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)Nc1cccc(O)c1	InChI=1S/C32H34F2N2O7S/c1-19(2)30-32(44(42,43)35-24-4-3-5-25(37)16-24)29(20-6-10-22(33)11-7-20)31(21-8-12-23(34)13-9-21)36(30)15-14-26(38)17-27(39)18-28(40)41/h3-13,16,19,26-27,35,37-39H,14-15,17-18H2,1-2H3,(H,40,41)/p-1/t26-,27-/m1/s1	LAGMRFZEFTXAGD-KAYWLYCHSA-M	50231031	CHEMBL252854::sodium; (3R,5R)-7-[2,3-bis-(4-fluoro-phenyl)-4-(3-hydroxy-phenylsulfamoyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9.4							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231031&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935523	104054960		CHEMBL252854			C03834	ZINC29037720	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408616	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)N1CCCCC1	InChI=1S/C31H39FN2O6S/c1-21(2)29-31(41(39,40)33-16-7-4-8-17-33)28(22-9-5-3-6-10-22)30(23-11-13-24(32)14-12-23)34(29)18-15-25(35)19-26(36)20-27(37)38/h3,5-6,9-14,21,25-26,35-36H,4,7-8,15-20H2,1-2H3,(H,37,38)/p-1/t25-,26-/m1/s1	LXVJYAUJKJERKM-CLJLJLNGSA-M	50231020	CHEMBL437783::sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(piperidin-1-ylsulfonyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.9							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231020	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231020&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935516	104054949		CHEMBL437783			C03834	ZINC29037709	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408617	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)Nc1cccc(c1)C(N)=O	InChI=1S/C33H35F2N3O7S/c1-19(2)30-32(46(44,45)37-25-5-3-4-22(16-25)33(36)43)29(20-6-10-23(34)11-7-20)31(21-8-12-24(35)13-9-21)38(30)15-14-26(39)17-27(40)18-28(41)42/h3-13,16,19,26-27,37,39-40H,14-15,17-18H2,1-2H3,(H2,36,43)(H,41,42)/p-1/t26-,27-/m1/s1	ISGYEZYSDGYQME-KAYWLYCHSA-M	50231030	CHEMBL265899::sodium; (3R,5R)-7-[3-(3-carbamoyl-phenylsulfamoyl)-4,5-bis-(4-fluoro-phenyl)-2-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 18							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231030	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231030&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935522	104054959		CHEMBL265899			C03834	ZINC29037715	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408618	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)NCc1ccccc1	InChI=1S/C33H36F2N2O6S/c1-21(2)31-33(44(42,43)36-20-22-6-4-3-5-7-22)30(23-8-12-25(34)13-9-23)32(24-10-14-26(35)15-11-24)37(31)17-16-27(38)18-28(39)19-29(40)41/h3-15,21,27-28,36,38-39H,16-20H2,1-2H3,(H,40,41)/p-1/t27-,28-/m1/s1	HSCBDNLELBVHGZ-VSGBNLITSA-M	50231032	CHEMBL252855::sodium; (3R,5R)-7-[3-benzylsulfamoyl-4,5-bis-(4-fluoro-phenyl)-2-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231032	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231032&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935524	104054961		CHEMBL252855			C03834	ZINC29037722	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408619	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)Nc1ccccc1	InChI=1S/C32H35FN2O6S/c1-21(2)30-32(42(40,41)34-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)31(23-13-15-24(33)16-14-23)35(30)18-17-26(36)19-27(37)20-28(38)39/h3-16,21,26-27,34,36-37H,17-20H2,1-2H3,(H,38,39)/p-1/t26-,27-/m1/s1	HLYOYBVEFIOLMM-KAYWLYCHSA-M	50231034	CHEMBL403646::sodium; (3R,5R)-7-[2-(4-fluoro-phenyl)-5-isopropyl-3-phenyl-4-phenylsulfamoyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231034	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231034&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935526	104054963		CHEMBL403646			C03834	ZINC29037744	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408620	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)N1CCSCC1	InChI=1S/C30H36F2N2O6S2/c1-19(2)28-30(42(39,40)33-13-15-41-16-14-33)27(20-3-7-22(31)8-4-20)29(21-5-9-23(32)10-6-21)34(28)12-11-24(35)17-25(36)18-26(37)38/h3-10,19,24-25,35-36H,11-18H2,1-2H3,(H,37,38)/p-1/t24-,25-/m1/s1	IKPHTPMSGDEMSI-JWQCQUIFSA-M	50231027	CHEMBL253053::sodium (3R,5R)-7-(2,3-bis(4-fluorophenyl)-5-isopropyl-4-(thiomorpholinosulfonyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9.7							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231027&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935520	104054956		CHEMBL253053			C03834	ZINC29037731	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408621	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)N1CCC1	InChI=1S/C29H35FN2O6S/c1-19(2)27-29(39(37,38)31-14-6-15-31)26(20-7-4-3-5-8-20)28(21-9-11-22(30)12-10-21)32(27)16-13-23(33)17-24(34)18-25(35)36/h3-5,7-12,19,23-24,33-34H,6,13-18H2,1-2H3,(H,35,36)/p-1/t23-,24-/m1/s1	BQXHXGRMRBSNNL-DNQXCXABSA-M	50231037	CHEMBL253054::sodium (3R,5R)-7-(3-(azetidin-1-ylsulfonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.8							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231037	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231037&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935529	104054966		CHEMBL253054			C03834	ZINC29037727	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408622	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)Nc1ccc(cc1)C(N)=O	InChI=1S/C33H35F2N3O7S/c1-19(2)30-32(46(44,45)37-25-13-7-22(8-14-25)33(36)43)29(20-3-9-23(34)10-4-20)31(21-5-11-24(35)12-6-21)38(30)16-15-26(39)17-27(40)18-28(41)42/h3-14,19,26-27,37,39-40H,15-18H2,1-2H3,(H2,36,43)(H,41,42)/p-1/t26-,27-/m1/s1	IYYNBGFAAGBIAX-KAYWLYCHSA-M	50231029	CHEMBL404671::sodium; (3R,5R)-7-[3-(4-carbamoyl-phenylsulfamoyl)-4,5-bis-(4-fluoro-phenyl)-2-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5.8							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231029	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231029&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44629675	104054958		CHEMBL404671			C03834	ZINC24974037	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408623	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)N(C)C	InChI=1S/C28H34F2N2O6S/c1-17(2)26-28(39(37,38)31(3)4)25(18-5-9-20(29)10-6-18)27(19-7-11-21(30)12-8-19)32(26)14-13-22(33)15-23(34)16-24(35)36/h5-12,17,22-23,33-34H,13-16H2,1-4H3,(H,35,36)/p-1/t22-,23-/m1/s1	CLOMKGVJEPOUAM-DHIUTWEWSA-M	50231038	CHEMBL253055::sodium; (3R,5R)-7-[3-dimethylsulfamoyl-4,5-bis-(4-fluoro-phenyl)-2-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.1							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231038&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935530	104054967		CHEMBL253055			C03834	ZINC29037729	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408624	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)Nc1ccc(F)cc1	InChI=1S/C32H33F3N2O6S/c1-19(2)30-32(44(42,43)36-25-13-11-24(35)12-14-25)29(20-3-7-22(33)8-4-20)31(21-5-9-23(34)10-6-21)37(30)16-15-26(38)17-27(39)18-28(40)41/h3-14,19,26-27,36,38-39H,15-18H2,1-2H3,(H,40,41)/p-1/t26-,27-/m1/s1	ZQHHYYLDSUBJLW-KAYWLYCHSA-M	50231022	CHEMBL437795::sodium; (3R,5R)-7-[2,3-bis-(4-fluoro-phenyl)-4-(4-fluoro-phenylsulfamoyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231022	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231022&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935517	104054951		CHEMBL437795			C03834	ZINC29037742	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408625	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)Nc1ccccc1	InChI=1S/C32H34F2N2O6S/c1-20(2)30-32(43(41,42)35-25-6-4-3-5-7-25)29(21-8-12-23(33)13-9-21)31(22-10-14-24(34)15-11-22)36(30)17-16-26(37)18-27(38)19-28(39)40/h3-15,20,26-27,35,37-38H,16-19H2,1-2H3,(H,39,40)/p-1/t26-,27-/m1/s1	GGTAZNWAYMFTSE-KAYWLYCHSA-M	50231039	CHEMBL252657::sodium; (3R,5R)-7-[2,3-bis-(4-fluoro-phenyl)-5-isopropyl-4-phenylsulfamoyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231039&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			58914909	104054968		CHEMBL252657			C03834	ZINC14208917	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408626	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)N(C)C	InChI=1S/C28H35FN2O6S/c1-18(2)26-28(38(36,37)30(3)4)25(19-8-6-5-7-9-19)27(20-10-12-21(29)13-11-20)31(26)15-14-22(32)16-23(33)17-24(34)35/h5-13,18,22-23,32-33H,14-17H2,1-4H3,(H,34,35)/p-1/t22-,23-/m1/s1	KDCOGIHYRPHRST-DHIUTWEWSA-M	50231036	CHEMBL437790::sodium; (3R,5R)-7-[3-dimethylsulfamoyl-5-(4-fluoro-phenyl)-2-isopropyl-4-phenyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.5							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935528	104054965		CHEMBL437790			C03834	ZINC29037725	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408627	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)N(C)Cc1ccccc1	InChI=1S/C34H38F2N2O6S/c1-22(2)32-34(45(43,44)37(3)21-23-7-5-4-6-8-23)31(24-9-13-26(35)14-10-24)33(25-11-15-27(36)16-12-25)38(32)18-17-28(39)19-29(40)20-30(41)42/h4-16,22,28-29,39-40H,17-21H2,1-3H3,(H,41,42)/p-1/t28-,29-/m1/s1	WOVMFAYOKUVUBG-FQLXRVMXSA-M	50231021	CHEMBL404672::sodium; (3R,5R)-7-[3-(benzyl-methyl-sulfamoyl)-4,5-bis-(4-fluoro-phenyl)-2-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231021&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			58914809	104054950		CHEMBL404672			C03834	ZINC29037739	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408628	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)S(=O)(=O)Nc1cccc(CC(N)=O)c1	InChI=1S/C34H37F2N3O7S/c1-20(2)32-34(47(45,46)38-26-5-3-4-21(16-26)17-29(37)42)31(22-6-10-24(35)11-7-22)33(23-8-12-25(36)13-9-23)39(32)15-14-27(40)18-28(41)19-30(43)44/h3-13,16,20,27-28,38,40-41H,14-15,17-19H2,1-2H3,(H2,37,42)(H,43,44)/p-1/t27-,28-/m1/s1	ZXGVFUKWWWNTTQ-VSGBNLITSA-M	50231035	CHEMBL401950::sodium; (3R,5R)-7-[3-(3-carbamoylmethyl-phenylsulfamoyl)-4,5-bis-(4-fluoro-phenyl)-2-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231035	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231035&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935527	104054964		CHEMBL401950			C03834	ZINC29037716	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408629	CC(C)c1c(c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)S(=O)(=O)N1CCOCC1	InChI=1S/C30H37FN2O7S/c1-20(2)28-30(41(38,39)32-14-16-40-17-15-32)27(21-6-4-3-5-7-21)29(22-8-10-23(31)11-9-22)33(28)13-12-24(34)18-25(35)19-26(36)37/h3-11,20,24-25,34-35H,12-19H2,1-2H3,(H,36,37)/p-1/t24-,25-/m1/s1	XLVZRBHNHHAPDT-JWQCQUIFSA-M	50231024	CHEMBL401949::sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-(morpholinosulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.5							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231024	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231024&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44629638	104054953		CHEMBL401949			C03834	ZINC24963177	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408630	CNS(=O)(=O)c1c(C(C)C)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1-c1ccc(F)cc1)-c1ccc(F)cc1	InChI=1S/C27H32F2N2O6S/c1-16(2)25-27(38(36,37)30-3)24(17-4-8-19(28)9-5-17)26(18-6-10-20(29)11-7-18)31(25)13-12-21(32)14-22(33)15-23(34)35/h4-11,16,21-22,30,32-33H,12-15H2,1-3H3,(H,34,35)/p-1/t21-,22-/m1/s1	IBOSEKWSKZSPPO-FGZHOGPDSA-M	50231033	CHEMBL438884::sodium; (3R,5R)-7-[2,3-bis-(4-fluoro-phenyl)-5-isopropyl-4-methylsulfamoyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 27							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50231033	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50231033&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935525	104054962		CHEMBL438884			C03834	ZINC14208925	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50408631	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O	InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1	BPRHUIZQVSMCRT-VEUZHWNKSA-N	18372	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::CHEMBL1496::Ros::Rosuvastatin::US9102656, Rosuvastatin ::ZD4522	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.7							ChEMBL	10.1016/j.bmcl.2007.11.124	10.7270/Q2TQ6191	18155906			Park, WK; Kennedy, RM; Larsen, SD; Miller, S; Roth, BD; Song, Y; Steinbaugh, BA; Sun, K; Tait, BD; Kowala, MC; Trivedi, BK; Auerbach, B; Askew, V; Dillon, L; Hanselman, JC; Lin, Z; Lu, GH; Robertson, A; Sekerke, C	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18372&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search		1HWL	446157	46518448	38545	CHEMBL1496	DB01098	2989	C03834	ZINC01535101	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463014	Cn1nnnc1C(CCC(O)CC(O)CC([O-])=O)Cc1ccc(F)cc1	InChI=1S/C17H23FN4O4/c1-22-17(19-20-21-22)12(8-11-2-5-13(18)6-3-11)4-7-14(23)9-15(24)10-16(25)26/h2-3,5-6,12,14-15,23-24H,4,7-10H2,1H3,(H,25,26)/p-1	AIRBQNIXTNNMBM-UHFFFAOYSA-M	50280058	CHEMBL8948::Sodium; 9-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nonanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>250000							ChEMBL	10.1016/S0960-894X(00)80665-4	10.7270/Q2X92B57				Balasubramanian, N; Brown, PJ; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280058&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935016	104121762		CHEMBL8948			C03834	ZINC40368700	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463015	Cn1nnnc1C(\C=C\C(O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H22F2N4O4/c1-29-23(26-27-28-29)20(11-10-18(30)12-19(31)13-21(32)33)22(14-2-6-16(24)7-3-14)15-4-8-17(25)9-5-15/h2-11,18-19,30-31H,12-13H2,1H3,(H,32,33)/p-1/b11-10+/t18?,19-/m1/s1	HPFIYXJJZZWEPC-GVAVTCRGSA-M	50011210	CHEMBL342422::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 43							ChEMBL	10.1016/S0960-894X(00)80665-4	10.7270/Q2X92B57				Balasubramanian, N; Brown, PJ; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011210	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011210&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947045	103923845		CHEMBL342422			C03834	ZINC25984555	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463016	Cn1nnnc1\C(\C=C\C(O)CC(O)CC([O-])=O)=C/c1ccc(F)cc1	InChI=1S/C17H19FN4O4/c1-22-17(19-20-21-22)12(8-11-2-5-13(18)6-3-11)4-7-14(23)9-15(24)10-16(25)26/h2-8,14-15,23-24H,9-10H2,1H3,(H,25,26)/p-1/b7-4+,12-8-	MFAXZXMXAKHTBS-JHLWKMQHSA-M	50280059	CHEMBL8800::Sodium; (6E,8Z)-9-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 210000							ChEMBL	10.1016/S0960-894X(00)80665-4	10.7270/Q2X92B57				Balasubramanian, N; Brown, PJ; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280059	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280059&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935017	104121763		CHEMBL8800			C03834	ZINC25985954	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463017	OC(CC(O)\C=C\c1c(-c2ccc(F)cc2)c2ccccc2n2nnnc12)CC([O-])=O	InChI=1S/C22H19FN4O4/c23-14-7-5-13(6-8-14)21-17-3-1-2-4-19(17)27-22(24-25-26-27)18(21)10-9-15(28)11-16(29)12-20(30)31/h1-10,15-16,28-29H,11-12H2,(H,30,31)/p-1/b10-9+	FBAGFKRGNNZVRT-MDZDMXLPSA-M	50280060	CHEMBL8746::Sodium; (E)-7-[5-(4-fluoro-phenyl)-1,2,3,9b-tetraaza-cyclopenta[a]naphthalen-4-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4600							ChEMBL	10.1016/S0960-894X(00)80665-4	10.7270/Q2X92B57				Balasubramanian, N; Brown, PJ; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280060&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935018	104121764		CHEMBL8746			C03834	ZINC25985524	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463018	Cn1nnnc1C(\C=C\C(O)CC(O)CC([O-])=O)=C1c2ccc(F)cc2-c2cc(F)ccc12	InChI=1S/C23H20F2N4O4/c1-29-23(26-27-28-29)18(7-4-14(30)10-15(31)11-21(32)33)22-16-5-2-12(24)8-19(16)20-9-13(25)3-6-17(20)22/h2-9,14-15,30-31H,10-11H2,1H3,(H,32,33)/p-1/b7-4+	FKJZGUOTNGCEHQ-QPJJXVBHSA-M	50280061	CHEMBL8633::Sodium; (E)-8-(3,6-difluoro-fluoren-9-ylidene)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-oct-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>4100							ChEMBL	10.1016/S0960-894X(00)80665-4	10.7270/Q2X92B57				Balasubramanian, N; Brown, PJ; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280061	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280061&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73755029	104121765		CHEMBL8633			C03834	ZINC25986121	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463019	Cn1nnnc1\C(\C=C\C(O)CC(O)CC([O-])=O)=C\c1ccc(F)cc1	InChI=1S/C17H19FN4O4/c1-22-17(19-20-21-22)12(8-11-2-5-13(18)6-3-11)4-7-14(23)9-15(24)10-16(25)26/h2-8,14-15,23-24H,9-10H2,1H3,(H,25,26)/p-1/b7-4+,12-8+	MFAXZXMXAKHTBS-HCFISPQYSA-M	50280062	CHEMBL8886::Sodium; (6E,8E)-9-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>250000							ChEMBL	10.1016/S0960-894X(00)80665-4	10.7270/Q2X92B57				Balasubramanian, N; Brown, PJ; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280062	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280062&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91935019	104121766		CHEMBL8886			C03834	ZINC25990839	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50464416	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19?,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-KVVRZSONSA-N	50004774	(S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-((R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::(lovastatin)2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(mevinolin)::CHEMBL503	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 32							ChEMBL	10.1016/S0960-894X(00)80623-X	10.7270/Q2NG4QJQ				Sit, SY; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004774&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6420024	103918321		CHEMBL503				ZINC04245664	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50464418	O[C@H](C[C@H](O)\C=C\C(=C(c1ccc(F)cc1)c1ccc(F)cc1)n1cnnn1)CC([O-])=O	InChI=1S/C22H20F2N4O4/c23-16-5-1-14(2-6-16)22(15-3-7-17(24)8-4-15)20(28-13-25-26-27-28)10-9-18(29)11-19(30)12-21(31)32/h1-10,13,18-19,29-30H,11-12H2,(H,31,32)/p-1/b10-9+/t18-,19-/m1/s1	XVOGPTRLJJHROM-BGGMYYEUSA-M	50280660	CHEMBL11891::Sodium; (E)-(3R,5S)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-tetrazol-1-yl-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20							ChEMBL	10.1016/S0960-894X(00)80623-X	10.7270/Q2NG4QJQ				Sit, SY; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280660&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934663	104122364		CHEMBL11891			C03834	ZINC03801965	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50464424	Cc1nnnn1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H22F2N4O4/c1-14-26-27-28-29(14)21(11-10-19(30)12-20(31)13-22(32)33)23(15-2-6-17(24)7-3-15)16-4-8-18(25)9-5-16/h2-11,19-20,30-31H,12-13H2,1H3,(H,32,33)/p-1/b11-10+/t19-,20-/m1/s1	JEUHSCHPIVRSFO-ANMDKAQQSA-M	50280661	CHEMBL276717::Sodium; (E)-(3R,5S)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(5-methyl-tetrazol-1-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100							ChEMBL	10.1016/S0960-894X(00)80623-X	10.7270/Q2NG4QJQ				Sit, SY; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280661	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280661&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934664	104122365		CHEMBL276717			C03834	ZINC13888340	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50464427	Cn1nnnc1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H22F2N4O4/c1-29-23(26-27-28-29)20(11-10-18(30)12-19(31)13-21(32)33)22(14-2-6-16(24)7-3-14)15-4-8-17(25)9-5-15/h2-11,18-19,30-31H,12-13H2,1H3,(H,32,33)/p-1/b11-10+/t18-,19-/m1/s1	HPFIYXJJZZWEPC-MMKWGKFASA-M	50014345	CHEMBL11804::Sodium; (E)-(3R,5S)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3200							ChEMBL	10.1016/S0960-894X(00)80623-X	10.7270/Q2NG4QJQ				Sit, SY; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014345&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18647991	103926367		CHEMBL11804			C03834	ZINC03782329	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463589	CCC(C)C(=O)O[C@H]1C[C@@H](C)C[C@@H]2C=C[C@H](C(C)C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C26H42O5/c1-6-17(5)26(29)31-23-12-16(4)11-18-7-9-21(15(2)3)22(25(18)23)10-8-20-13-19(27)14-24(28)30-20/h7,9,15-23,25,27H,6,8,10-14H2,1-5H3/t16-,17?,18-,19+,20+,21+,22-,23-,25-/m0/s1	DGUFEUXWCGWGJS-WBJXLNGTSA-N	50280347	2-Methyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-isopropyl-3-methyl-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL73641	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1000							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280347&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312652	104122051		CHEMBL73641				ZINC26379869	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463590	CCC(C)C(=O)O[C@H]1C[C@@H](C)C[C@@H]2C=C[C@H](C)[C@H](CCC(=O)C[C@@H](O)CC(=O)OC)[C@@H]12	InChI=1S/C25H40O6/c1-6-16(3)25(29)31-22-12-15(2)11-18-8-7-17(4)21(24(18)22)10-9-19(26)13-20(27)14-23(28)30-5/h7-8,15-18,20-22,24,27H,6,9-14H2,1-5H3/t15-,16?,17-,18-,20+,21-,22-,24-/m0/s1	TYBWDBSIVBOJJP-NTDSCLFKSA-N	50280348	(R)-7-[(1S,2S,4aR,6S,8S,8aS)-2,6-Dimethyl-8-(2-methyl-butyryloxy)-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl]-3-hydroxy-5-oxo-heptanoic acid methyl ester::CHEMBL76113	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 80							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280348&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312979	104122052		CHEMBL76113				ZINC26383566	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463591	CCC(C)(C)C(=O)O[C@H]1C[C@H](C[C@@H]2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12)\C=C\Cc1ccccc1	InChI=1S/C33H46O5/c1-5-33(3,4)32(36)38-29-19-24(13-9-12-23-10-7-6-8-11-23)18-25-15-14-22(2)28(31(25)29)17-16-27-20-26(34)21-30(35)37-27/h6-11,13-15,22,24-29,31,34H,5,12,16-21H2,1-4H3/b13-9+/t22-,24-,25-,26+,27+,28-,29-,31-/m0/s1	NXQINZKEHMOHBO-CUUGDKJGSA-N	50280349	2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-((E)-3-phenyl-propenyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL310922	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280349&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44313278	104122053		CHEMBL310922				ZINC03925419	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463592	CC[C@H](C)C(=O)O[C@H]1C[C@H](C[C@@H]2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12)\C=C\Cc1ccccc1	InChI=1S/C32H44O5/c1-4-21(2)32(35)37-29-18-24(12-8-11-23-9-6-5-7-10-23)17-25-14-13-22(3)28(31(25)29)16-15-27-19-26(33)20-30(34)36-27/h5-10,12-14,21-22,24-29,31,33H,4,11,15-20H2,1-3H3/b12-8+/t21-,22-,24-,25-,26+,27+,28-,29-,31-/m0/s1	HAUZUJHNCKBVKD-UPMVUGGKSA-N	50280350	(S)-2-Methyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-((E)-3-phenyl-propenyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL77486	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280350&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44313279	104122054		CHEMBL77486				ZINC03925417	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463593	CCC(C)(C)C(=O)O[C@H]1C[C@H](C[C@@H]2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12)\C=C\C(C)C	InChI=1S/C29H46O5/c1-7-29(5,6)28(32)34-25-15-20(10-8-18(2)3)14-21-11-9-19(4)24(27(21)25)13-12-23-16-22(30)17-26(31)33-23/h8-11,18-25,27,30H,7,12-17H2,1-6H3/b10-8+/t19-,20-,21-,22+,23+,24-,25-,27-/m0/s1	BVAPITSIAAZGKC-JKLUYXJFSA-N	50280351	2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-((E)-3-methyl-but-1-enyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL431580	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1200							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280351&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44313306	104122055		CHEMBL431580				ZINC26382916	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463594	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19?,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-KVVRZSONSA-N	50004774	(S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-((R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::(lovastatin)2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(mevinolin)::CHEMBL503	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 11							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004774&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6420024	103918321		CHEMBL503				ZINC04245664	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463595	CCC\C(C)=C\[C@@H]1C[C@H](OC(=O)[C@@H](C)CC)[C@H]2[C@H](C1)C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C29H46O5/c1-6-8-18(3)13-21-14-22-10-9-20(5)25(12-11-24-16-23(30)17-27(31)33-24)28(22)26(15-21)34-29(32)19(4)7-2/h9-10,13,19-26,28,30H,6-8,11-12,14-17H2,1-5H3/b18-13+/t19-,20-,21-,22-,23+,24+,25-,26-,28-/m0/s1	RUUJXRLFCRZHNV-HTMOGKDHSA-N	50280352	(S)-2-Methyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-((E)-2-methyl-pent-1-enyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL309095	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280352&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312986	104122056		CHEMBL309095				ZINC26376828	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463596	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C[C@@H]2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H38O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,14-21,23,25H,5,8-13H2,1-4H3/t14-,15-,16-,17-,18+,19+,20-,21-,23-/m0/s1	IFIFFBWHLKGTMO-SJIDJMGWSA-N	50280353	(S)-2-Methyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL76114	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280353&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11080021	104122057		CHEMBL76114				ZINC26383570	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463597	CCC(C)C(=O)O[C@H]1C[C@@H](C)C[C@@H]2C=C[C@H](C(C)C)[C@H](CCC(=O)C[C@@H](O)CC(=O)OC)[C@@H]12	InChI=1S/C27H44O6/c1-7-18(5)27(31)33-24-13-17(4)12-19-8-10-22(16(2)3)23(26(19)24)11-9-20(28)14-21(29)15-25(30)32-6/h8,10,16-19,21-24,26,29H,7,9,11-15H2,1-6H3/t17-,18?,19-,21+,22+,23-,24-,26-/m0/s1	FPDPJFFHQHKQBE-QCBSSCQQSA-N	50280354	(R)-3-Hydroxy-7-[(1S,2S,4aR,6S,8S,8aS)-2-isopropyl-6-methyl-8-(2-methyl-butyryloxy)-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl]-5-oxo-heptanoic acid methyl ester::CHEMBL305874	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6000							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280354&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312690	104122058		CHEMBL305874				ZINC26376651	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463598	CCC(C)(C)C(=O)O[C@H]1C[C@H](C[C@@H]2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12)\C=C\C	InChI=1S/C27H42O5/c1-6-8-18-13-19-10-9-17(3)22(12-11-21-15-20(28)16-24(29)31-21)25(19)23(14-18)32-26(30)27(4,5)7-2/h6,8-10,17-23,25,28H,7,11-16H2,1-5H3/b8-6+/t17-,18-,19-,20+,21+,22-,23-,25-/m0/s1	FPFKPDQXLUTVQE-XNFUBWTISA-N	50280355	2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-((E)-propenyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL306113	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280355&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			9803625	104122059		CHEMBL306113				ZINC03925404	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463599	CCC(C)(C)C(=O)O[C@H]1C[C@](C)(C[C@@H]2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12)\C=C\C	InChI=1S/C28H44O5/c1-7-13-28(6)16-19-10-9-18(3)22(12-11-21-14-20(29)15-24(30)32-21)25(19)23(17-28)33-26(31)27(4,5)8-2/h7,9-10,13,18-23,25,29H,8,11-12,14-17H2,1-6H3/b13-7+/t18-,19-,20+,21+,22-,23-,25-,28-/m0/s1	ULLNOURAZVAUBJ-ZCMVFQNISA-N	50280356	2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-3-((E)-propenyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL73298	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280356&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44313297	104122060		CHEMBL73298				ZINC03915377	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463600	CC\C=C\[C@@H]1C[C@H](OC(=O)C(C)(C)CC)[C@H]2[C@H](C1)C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C28H44O5/c1-6-8-9-19-14-20-11-10-18(3)23(13-12-22-16-21(29)17-25(30)32-22)26(20)24(15-19)33-27(31)28(4,5)7-2/h8-11,18-24,26,29H,6-7,12-17H2,1-5H3/b9-8+/t18-,19-,20-,21+,22+,23-,24-,26-/m0/s1	YELWPEUCSMCSPZ-NCZQOOMNSA-N	50280357	2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-3-((E)-but-1-enyl)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL72799	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280357&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312998	104122061		CHEMBL72799				ZINC03925405	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463601	CCC(C)C(=O)O[C@H]1C[C@@H](C)C[C@@H]2C=CC[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H36O5/c1-4-15(3)23(26)28-20-11-14(2)10-17-7-5-6-16(22(17)20)8-9-19-12-18(24)13-21(25)27-19/h5,7,14-20,22,24H,4,6,8-13H2,1-3H3/t14-,15?,16+,17-,18+,19+,20-,22+/m0/s1	WHOSSWGCARIJDM-FKNYLGRYSA-N	50280358	2-Methyl-butyric acid (1S,3S,4aR,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3-methyl-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL430427	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1500							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280358	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280358&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312658	104122062		CHEMBL430427				ZINC26378297	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463602	CC[C@H](C)C(=O)O[C@H]1C[C@H](C[C@@H]2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12)\C=C/C	InChI=1S/C26H40O5/c1-5-7-18-12-19-9-8-17(4)22(11-10-21-14-20(27)15-24(28)30-21)25(19)23(13-18)31-26(29)16(3)6-2/h5,7-9,16-23,25,27H,6,10-15H2,1-4H3/b7-5-/t16-,17-,18-,19-,20+,21+,22-,23-,25-/m0/s1	CUCZESZCSRJKHQ-PKDMDHCWSA-N	50280359	(S)-2-Methyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-((Z)-propenyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL305676	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280359&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312680	104122063		CHEMBL305676				ZINC13890999	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463603	CCC(C)(C)C(=O)O[C@H]1C[C@H](C[C@@H]2C=C[C@H](C)[C@H](\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12)\C=C\C	InChI=1S/C27H40O5/c1-6-8-18-13-19-10-9-17(3)22(12-11-21-15-20(28)16-24(29)31-21)25(19)23(14-18)32-26(30)27(4,5)7-2/h6,8-12,17-23,25,28H,7,13-16H2,1-5H3/b8-6+,12-11+/t17-,18-,19-,20+,21+,22-,23-,25-/m0/s1	WELJUFAEWJIDMN-NHGLKZNXSA-N	50280360	2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[(E)-2-((2S,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-vinyl]-7-methyl-3-((E)-propenyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL76073	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280360&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44313015	104122064		CHEMBL76073				ZINC26385385	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463604	C\C=C/[C@@H]1C[C@H](OC(C)=O)[C@H]2[C@H](C1)C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C23H34O5/c1-4-5-16-10-17-7-6-14(2)20(23(17)21(11-16)27-15(3)24)9-8-19-12-18(25)13-22(26)28-19/h4-7,14,16-21,23,25H,8-13H2,1-3H3/b5-4-/t14-,16-,17-,18+,19+,20-,21-,23-/m0/s1	USQIRGUWDVHVHW-KLYIYTIGSA-N	50280361	Acetic acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-((Z)-propenyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL423674	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1500							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280361&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312640	104122065		CHEMBL423674				ZINC26379716	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463605	CC[C@H](C)C(=O)O[C@H]1C[C@H](C[C@@H]2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12)\C=C\C	InChI=1S/C26H40O5/c1-5-7-18-12-19-9-8-17(4)22(11-10-21-14-20(27)15-24(28)30-21)25(19)23(13-18)31-26(29)16(3)6-2/h5,7-9,16-23,25,27H,6,10-15H2,1-4H3/b7-5+/t16-,17-,18-,19-,20+,21+,22-,23-,25-/m0/s1	CUCZESZCSRJKHQ-ZQLHKXBASA-N	50280362	(S)-2-Methyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-((E)-propenyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL305949	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280362&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312637	104122066		CHEMBL305949				ZINC03925402	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463606	CCCC(C)(C)C(=O)O[C@H]1C[C@H](C[C@@H]2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12)\C=C/C	InChI=1S/C28H44O5/c1-6-8-19-14-20-10-9-18(3)23(12-11-22-16-21(29)17-25(30)32-22)26(20)24(15-19)33-27(31)28(4,5)13-7-2/h6,8-10,18-24,26,29H,7,11-17H2,1-5H3/b8-6-/t18-,19-,20-,21+,22+,23-,24-,26-/m0/s1	LXCWFROQZQLQQQ-HXYZHAITSA-N	50280363	2,2-Dimethyl-pentanoic acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-((Z)-propenyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL75832	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280363&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312638	104122067		CHEMBL75832				ZINC26385405	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463607	CCC\C(C)=C\[C@@H]1C[C@H](OC(=O)C(C)(C)CC)[C@H]2[C@H](C1)C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C30H48O5/c1-7-9-19(3)14-21-15-22-11-10-20(4)25(13-12-24-17-23(31)18-27(32)34-24)28(22)26(16-21)35-29(33)30(5,6)8-2/h10-11,14,20-26,28,31H,7-9,12-13,15-18H2,1-6H3/b19-14+/t20-,21-,22-,23+,24+,25-,26-,28-/m0/s1	IEAZBAXMXAEWIL-FDAOGXNOSA-N	50280364	2,2-Dimethyl-butyric acid (1S,3S,4aR,7S,8S,8aS)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-3-((E)-2-methyl-pent-1-enyl)-1,2,3,4,4a,7,8,8a-octahydro-naphthalen-1-yl ester::CHEMBL72806	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8							ChEMBL	10.1016/S0960-894X(01)81069-6	10.7270/Q28C9W59				Bone, EA; Cunningham, EM; Davidson, AH; Galloway, WA; Lewis, CN; Morrice, EM; Reeve, MM; Todd, RS; White, IM	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280364&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44312985	104122068		CHEMBL72806				ZINC26376644	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463679	[Na+].C[C@H](CC(O)CC(O)CC([O-])=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](OC(=O)C(C)(C)C)[C@]12C	InChI=1S/C32H54O8.Na/c1-17(11-20(34)14-21(35)15-27(37)38)22-7-8-23-28-24(16-26(32(22,23)6)40-29(39)30(2,3)4)31(5)10-9-19(33)12-18(31)13-25(28)36;/h17-26,28,33-36H,7-16H2,1-6H3,(H,37,38);/q;+1/p-1/t17-,18+,19-,20?,21?,22-,23+,24+,25-,26+,28+,31+,32-;/m1./s1	KPBHQDPBKPRQHK-UQXDZCGUSA-M	50280408	CHEMBL3138233::Sodium; (R)-7-[(3R,5S,7R,10S,12S,13R,17R)-12-(2,2-dimethyl-propionyloxy)-3,7-dihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-3,5-dihydroxy-octanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12300							ChEMBL	10.1016/S0960-894X(01)80201-8	10.7270/Q24Q7TWB				Menear, KA; Patel, D; Clay, V; Howes, C; Taylor, PW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280408&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			76333138	104122112		CHEMBL3138233				ZINC43845631	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463680	CC[C@@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12	InChI=1S/C24H38O6/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28/h6-7,10,14-16,18-21,23,25-26H,5,8-9,11-13H2,1-4H3,(H,27,28)/t14-,15+,16-,18+,19+,20-,21-,23-/m0/s1	QLJODMDSTUBWDW-YPQFMRJXSA-N	50280409	(3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-Dimethyl-8-((R)-2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-3,5-dihydroxy-heptanoic acid::CHEMBL330439	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3690							ChEMBL	10.1016/S0960-894X(01)80201-8	10.7270/Q24Q7TWB				Menear, KA; Patel, D; Clay, V; Howes, C; Taylor, PW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280409&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			29982785	104122113		CHEMBL330439			C03834	ZINC22061901	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50463681	[Na+].C[C@H](CC(O)CC(O)CC([O-])=O)[C@H]1CC[C@H]2[C@@H]3[C@@H](C[C@@H]4C[C@@H](CC[C@]4(C)[C@H]3C[C@H](OC(C)=O)[C@]12C)OC(C)=O)OC(C)=O	InChI=1S/C33H52O10.Na/c1-17(11-22(37)14-23(38)15-30(39)40)25-7-8-26-31-27(16-29(33(25,26)6)43-20(4)36)32(5)10-9-24(41-18(2)34)12-21(32)13-28(31)42-19(3)35;/h17,21-29,31,37-38H,7-16H2,1-6H3,(H,39,40);/q;+1/p-1/t17-,21+,22?,23?,24-,25-,26+,27+,28-,29+,31+,32+,33-;/m1./s1	OHNKBJBXCWURLQ-WXDRIHQVSA-M	50280410	CHEMBL3138409::Sodium; (R)-3,5-dihydroxy-7-((3R,5S,7R,10S,12S,13R,17R)-3,7,12-triacetoxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-octanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 39200							ChEMBL	10.1016/S0960-894X(01)80201-8	10.7270/Q24Q7TWB				Menear, KA; Patel, D; Clay, V; Howes, C; Taylor, PW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50280410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50280410&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			76322301	104122114		CHEMBL3138409				ZINC44247060	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486318	CC(C)c1sc(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1ccccc1	InChI=1S/C26H27FO4S/c1-16(2)25-22(13-12-20(28)14-21(29)15-23(30)31)24(17-8-10-19(27)11-9-17)26(32-25)18-6-4-3-5-7-18/h3-13,16,20-21,28-29H,14-15H2,1-2H3,(H,30,31)/p-1/b13-12+/t20-,21-/m1/s1	JINWNWAVDADLDL-DDVDASKDSA-M	50291237	CHEMBL153492::Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-phenyl)-2-isopropyl-5-phenyl-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.4							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291237	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291237&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934587	104132789		CHEMBL153492			C03834	ZINC27637928	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486319	CC(C)c1sc(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1F)-c1ccccc1	InChI=1S/C26H27FO4S/c1-16(2)25-21(13-12-18(28)14-19(29)15-23(30)31)24(20-10-6-7-11-22(20)27)26(32-25)17-8-4-3-5-9-17/h3-13,16,18-19,28-29H,14-15H2,1-2H3,(H,30,31)/p-1/b13-12+/t18-,19-/m1/s1	HXUYZSBLSLAWGI-WTWCKAPFSA-M	50291238	CHEMBL434313::Sodium; (E)-(3R,5S)-7-[4-(2-fluoro-phenyl)-2-isopropyl-5-phenyl-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 233							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291238	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291238&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934588	104132790		CHEMBL434313			C03834	ZINC27637940	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486320	CC(C)c1sc(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1)-c1ccccc1	InChI=1S/C26H28O4S/c1-17(2)25-22(14-13-20(27)15-21(28)16-23(29)30)24(18-9-5-3-6-10-18)26(31-25)19-11-7-4-8-12-19/h3-14,17,20-21,27-28H,15-16H2,1-2H3,(H,29,30)/p-1/b14-13+/t20-,21-/m1/s1	JUWLWTYHUUUWJC-SVKRATOZSA-M	50291239	CHEMBL151961::Sodium; (E)-(3R,5S)-3,5-dihydroxy-7-(2-isopropyl-4,5-diphenyl-thiophen-3-yl)-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 26							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291239&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934589	104132791		CHEMBL151961			C03834	ZINC27638999	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486321	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCCC[C@@H](O)CC([O-])=O)[C@@H]12	InChI=1S/C24H38O5/c1-5-16(3)24(28)29-21-13-15(2)12-18-11-10-17(4)20(23(18)21)9-7-6-8-19(25)14-22(26)27/h10-12,15-17,19-21,23,25H,5-9,13-14H2,1-4H3,(H,26,27)/p-1/t15-,16-,17-,19+,20-,21-,23-/m0/s1	KMKJGDLERVBTLL-PUKJOLFJSA-M	50291240	CHEMBL152032::Sodium; (R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-((S)-2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-3-hydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 160							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291240&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934590	104132792		CHEMBL152032			C03834	ZINC13834024	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486322	COc1ccc(cc1)-c1sc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1	InChI=1S/C27H29FO5S/c1-16(2)26-23(13-10-20(29)14-21(30)15-24(31)32)25(17-4-8-19(28)9-5-17)27(34-26)18-6-11-22(33-3)12-7-18/h4-13,16,20-21,29-30H,14-15H2,1-3H3,(H,31,32)/p-1/b13-10+/t20-,21-/m1/s1	RGKGLDUORXLGSC-PKGLBKFNSA-M	50291241	CHEMBL153021::Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-phenyl)-2-isopropyl-5-(4-methoxy-phenyl)-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6.3							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291241	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291241&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934591	104132793		CHEMBL153021			C03834	ZINC27634328	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486323	CCCCCCCCc1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(sc1-c1ccccc1)C(C)C	InChI=1S/C28H40O4S/c1-4-5-6-7-8-12-15-24-25(17-16-22(29)18-23(30)19-26(31)32)27(20(2)3)33-28(24)21-13-10-9-11-14-21/h9-11,13-14,16-17,20,22-23,29-30H,4-8,12,15,18-19H2,1-3H3,(H,31,32)/p-1/b17-16+/t22-,23-/m1/s1	RAEJMKLYBFNQAL-NHAHDSLOSA-M	50291242	CHEMBL347095::Sodium; (E)-(3R,5S)-3,5-dihydroxy-7-(2-isopropyl-4-octyl-5-phenyl-thiophen-3-yl)-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>10000							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291242	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291242&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934592	104132794		CHEMBL347095			C03834	ZINC43920140	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486324	CC(C)c1sc(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1cccc(F)c1)-c1ccccc1	InChI=1S/C26H27FO4S/c1-16(2)25-22(12-11-20(28)14-21(29)15-23(30)31)24(18-9-6-10-19(27)13-18)26(32-25)17-7-4-3-5-8-17/h3-13,16,20-21,28-29H,14-15H2,1-2H3,(H,30,31)/p-1/b12-11+/t20-,21-/m1/s1	ZVFVFQUUSPECBX-LKWCPCFXSA-M	50291243	CHEMBL152926::Sodium; (E)-(3R,5S)-7-[4-(3-fluoro-phenyl)-2-isopropyl-5-phenyl-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 49							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291243	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291243&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934593	104132795		CHEMBL152926			C03834	ZINC27633020	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486325	CC(C)c1sc(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1cccc(c1)C(F)(F)F)-c1ccccc1	InChI=1S/C27H27F3O4S/c1-16(2)25-22(12-11-20(31)14-21(32)15-23(33)34)24(26(35-25)17-7-4-3-5-8-17)18-9-6-10-19(13-18)27(28,29)30/h3-13,16,20-21,31-32H,14-15H2,1-2H3,(H,33,34)/p-1/b12-11+/t20-,21-/m1/s1	PFAXPTGCEKXRRF-LKWCPCFXSA-M	50291244	CHEMBL150649::Sodium; (E)-(3R,5S)-3,5-dihydroxy-7-[2-isopropyl-5-phenyl-4-(3-trifluoromethyl-phenyl)-thiophen-3-yl]-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2980							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291244&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934594	104132796		CHEMBL150649			C03834	ZINC27628571	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486326	CC(C)c1sc(CO)c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C21H25FO5S/c1-12(2)21-17(8-7-15(24)9-16(25)10-19(26)27)20(18(11-23)28-21)13-3-5-14(22)6-4-13/h3-8,12,15-16,23-25H,9-11H2,1-2H3,(H,26,27)/p-1/b8-7+/t15-,16-/m1/s1	OTSVPKASEZEHDA-XLBHYRNJSA-M	50291245	CHEMBL347277::Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-phenyl)-5-hydroxymethyl-2-isopropyl-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 325							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291245&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934595	104132797		CHEMBL347277			C03834	ZINC27632801	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486327	COc1ccc(cc1)-c1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(sc1-c1ccccc1)C(C)C	InChI=1S/C27H30O5S/c1-17(2)26-23(14-11-20(28)15-21(29)16-24(30)31)25(18-9-12-22(32-3)13-10-18)27(33-26)19-7-5-4-6-8-19/h4-14,17,20-21,28-29H,15-16H2,1-3H3,(H,30,31)/p-1/b14-11+/t20-,21-/m1/s1	KUSQOVJFJSSLFT-OKYCLFFTSA-M	50291246	CHEMBL346635::Sodium; (E)-(3R,5S)-3,5-dihydroxy-7-[2-isopropyl-4-(4-methoxy-phenyl)-5-phenyl-thiophen-3-yl]-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2430							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291246&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934596	104132798		CHEMBL346635			C03834	ZINC27638975	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486328	CC(C)c1sc(C2CCCC2)c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C25H31FO4S/c1-15(2)24-21(12-11-19(27)13-20(28)14-22(29)30)23(16-7-9-18(26)10-8-16)25(31-24)17-5-3-4-6-17/h7-12,15,17,19-20,27-28H,3-6,13-14H2,1-2H3,(H,29,30)/p-1/b12-11+/t19-,20-/m1/s1	XFKYWJPYYRTYBR-XICOBVEKSA-M	50291247	CHEMBL154868::Sodium; (E)-(3R,5S)-7-[5-cyclopentyl-4-(4-fluoro-phenyl)-2-isopropyl-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 570							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291247&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934597	104132799		CHEMBL154868			C03834	ZINC27632302	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486329	COCCOCc1sc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1	InChI=1S/C24H31FO6S/c1-15(2)24-20(9-8-18(26)12-19(27)13-22(28)29)23(16-4-6-17(25)7-5-16)21(32-24)14-31-11-10-30-3/h4-9,15,18-19,26-27H,10-14H2,1-3H3,(H,28,29)/p-1/b9-8+/t18-,19-/m1/s1	RPTBVDQITSDSED-TYFAACHXSA-M	50291248	CHEMBL358245::Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-phenyl)-2-isopropyl-5-(2-methoxy-ethoxymethyl)-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 206							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291248&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934598	104132800		CHEMBL358245			C03834	ZINC27632308	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486330	CC(C)c1sc(c(C2CCCC2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C25H32O4S/c1-16(2)24-21(13-12-19(26)14-20(27)15-22(28)29)23(17-8-6-7-9-17)25(30-24)18-10-4-3-5-11-18/h3-5,10-13,16-17,19-20,26-27H,6-9,14-15H2,1-2H3,(H,28,29)/p-1/b13-12+/t19-,20-/m1/s1	VERCRDKCPMBEFN-OKLSWEBGSA-M	50291249	CHEMBL348225::Sodium; (E)-(3R,5S)-7-(4-cyclopentyl-2-isopropyl-5-phenyl-thiophen-3-yl)-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 417							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291249&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934599	104132801		CHEMBL348225			C03834	ZINC27639610	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486331	CC(C)c1sc(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(cc1)-c1ccccc1)-c1ccccc1	InChI=1S/C32H32O4S/c1-21(2)31-28(18-17-26(33)19-27(34)20-29(35)36)30(32(37-31)25-11-7-4-8-12-25)24-15-13-23(14-16-24)22-9-5-3-6-10-22/h3-18,21,26-27,33-34H,19-20H2,1-2H3,(H,35,36)/p-1/b18-17+/t26-,27-/m1/s1	WVLJHWOGFTYJBU-VTGNGFHBSA-M	50291250	CHEMBL358171::Sodium; (E)-(3R,5S)-7-(4-biphenyl-4-yl-2-isopropyl-5-phenyl-thiophen-3-yl)-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>10000							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291250&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934600	104132802		CHEMBL358171			C03834	ZINC27635925	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486332	CC(C)c1sc(C)c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C21H26O4S/c1-13(2)21-18(10-9-16(22)11-17(23)12-19(24)25)20(14(3)26-21)15-7-5-4-6-8-15/h4-10,13,16-17,22-23H,11-12H2,1-3H3,(H,24,25)/p-1/b10-9+/t16-,17-/m1/s1	WIWLHMZABOLRPC-VEUZHWNKSA-M	50291251	CHEMBL346856::Sodium; (E)-(3R,5S)-3,5-dihydroxy-7-(2-isopropyl-5-methyl-4-phenyl-thiophen-3-yl)-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 94							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291251&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934601	104132803		CHEMBL346856			C03834	ZINC27639160	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486333	CC(C)c1sc(C(C)C)c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C23H29FO4S/c1-13(2)22-19(10-9-17(25)11-18(26)12-20(27)28)21(23(29-22)14(3)4)15-5-7-16(24)8-6-15/h5-10,13-14,17-18,25-26H,11-12H2,1-4H3,(H,27,28)/p-1/b10-9+/t17-,18-/m1/s1	TZFHDGAWYDEWTC-AQRBRUGDSA-M	50291252	CHEMBL152551::Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-phenyl)-2,5-diisopropyl-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 26							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291252&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934602	104132804		CHEMBL152551			C03834	ZINC02002065	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486334	CC(C)c1sc(c(-c2cccs2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C24H26O4S2/c1-15(2)23-19(11-10-17(25)13-18(26)14-21(27)28)22(20-9-6-12-29-20)24(30-23)16-7-4-3-5-8-16/h3-12,15,17-18,25-26H,13-14H2,1-2H3,(H,27,28)/p-1/b11-10+/t17-,18-/m1/s1	SSKPPTWXEIXROR-NDZBKKTDSA-M	50291253	CHEMBL152114::Sodium; (E)-(3R,5S)-3,5-dihydroxy-7-(5'-isopropyl-2'-phenyl-[2,3']bithiophenyl-4'-yl)-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1420							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291253&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934603	104132805		CHEMBL152114			C03834	ZINC27640814	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486335	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CCCC[C@@H](O)CC([O-])=O)[C@@H]12	InChI=1S/C23H36O5/c1-4-15(2)23(27)28-20-11-7-8-17-13-12-16(3)19(22(17)20)10-6-5-9-18(24)14-21(25)26/h8,12-13,15-16,18-20,22,24H,4-7,9-11,14H2,1-3H3,(H,25,26)/p-1/t15-,16-,18+,19-,20-,22-/m0/s1	YISUQKCHRLMYIA-FLNPMPMESA-M	50291254	CHEMBL357515::Sodium; (R)-3-hydroxy-7-[(1S,2S,8S,8aR)-2-methyl-8-((S)-2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 110							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291254&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934604	104132806		CHEMBL357515			C03834	ZINC27634358	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486336	CC(C)c1sc(C=C(C)C)c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C24H29FO4S/c1-14(2)11-21-23(16-5-7-17(25)8-6-16)20(24(30-21)15(3)4)10-9-18(26)12-19(27)13-22(28)29/h5-11,15,18-19,26-27H,12-13H2,1-4H3,(H,28,29)/p-1/b10-9+/t18-,19-/m1/s1	CKBYQGWSLCUVDB-BGGMYYEUSA-M	50291255	CHEMBL358623::Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-phenyl)-2-isopropyl-5-(2-methyl-propenyl)-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291255&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934605	104132807		CHEMBL358623			C03834	ZINC27639165	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486337	CC(C)c1sc(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1ccc(Cl)cc1	InChI=1S/C26H26ClFO4S/c1-15(2)25-22(12-11-20(29)13-21(30)14-23(31)32)24(16-5-9-19(28)10-6-16)26(33-25)17-3-7-18(27)8-4-17/h3-12,15,20-21,29-30H,13-14H2,1-2H3,(H,31,32)/p-1/b12-11+/t20-,21-/m1/s1	RMSXTVRZGZXJKJ-LKWCPCFXSA-M	50291256	CHEMBL152129::Sodium; (E)-(3R,5S)-7-[5-(4-chloro-phenyl)-4-(4-fluoro-phenyl)-2-isopropyl-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 21							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291256&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934606	104132808		CHEMBL152129			C03834	ZINC27643800	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486338	CCCCCCCCc1sc(C(C)C)c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1	InChI=1S/C28H39FO4S/c1-4-5-6-7-8-9-10-25-27(20-11-13-21(29)14-12-20)24(28(34-25)19(2)3)16-15-22(30)17-23(31)18-26(32)33/h11-16,19,22-23,30-31H,4-10,17-18H2,1-3H3,(H,32,33)/p-1/b16-15+/t22-,23-/m1/s1	XAXRDRNCPUESMZ-LBBXHWODSA-M	50291257	CHEMBL152963::Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-phenyl)-2-isopropyl-5-octyl-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>10000							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291257&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934607	104132809		CHEMBL152963			C03834	ZINC43411587	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486339	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1150							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486340	CC(C)c1sc(c(c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1)-c1ccc(C)cc1	InChI=1S/C27H29FO4S/c1-16(2)26-23(13-12-21(29)14-22(30)15-24(31)32)25(18-8-10-20(28)11-9-18)27(33-26)19-6-4-17(3)5-7-19/h4-13,16,21-22,29-30H,14-15H2,1-3H3,(H,31,32)/p-1/b13-12+/t21-,22-/m1/s1	MVSMTXJIJKVMLF-ITWZMISCSA-M	50291258	CHEMBL152366::Sodium; (E)-(3R,5S)-7-[4-(4-fluoro-phenyl)-2-isopropyl-5-p-tolyl-thiophen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9.7							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291258&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934608	104132810		CHEMBL152366			C03834	ZINC27644009	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486341	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CCC3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19?,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-KVVRZSONSA-N	50004774	(S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-((R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::(lovastatin)2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(mevinolin)::CHEMBL503	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 530							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004774&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6420024	103918321		CHEMBL503				ZINC04245664	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486342	CC(C)c1sc(c(C2CCCCC2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C26H34O4S/c1-17(2)25-22(14-13-20(27)15-21(28)16-23(29)30)24(18-9-5-3-6-10-18)26(31-25)19-11-7-4-8-12-19/h4,7-8,11-14,17-18,20-21,27-28H,3,5-6,9-10,15-16H2,1-2H3,(H,29,30)/p-1/b14-13+/t20-,21-/m1/s1	ZTZBCTWWLWASMT-SVKRATOZSA-M	50291259	CHEMBL152893::Sodium; (E)-(3R,5S)-7-(4-cyclohexyl-2-isopropyl-5-phenyl-thiophen-3-yl)-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 202							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291259&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934609	104132811		CHEMBL152893			C03834	ZINC27630612	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50486343	CC(C)c1sc(c(C=C(C)C)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C24H30O4S/c1-15(2)12-21-20(11-10-18(25)13-19(26)14-22(27)28)23(16(3)4)29-24(21)17-8-6-5-7-9-17/h5-12,16,18-19,25-26H,13-14H2,1-4H3,(H,27,28)/p-1/b11-10+/t18-,19-/m1/s1	IOVMFFDXHBYEHC-MMKWGKFASA-M	50291260	CHEMBL154986::Sodium; (E)-(3R,5S)-3,5-dihydroxy-7-[2-isopropyl-4-(2-methyl-propenyl)-5-phenyl-thiophen-3-yl]-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1000							ChEMBL	10.1016/S0960-894X(97)00065-6	10.7270/Q2RB74NQ				Coppola, GM; Damon, RE; Yu, H; Engstrom, RG; Scallen, TJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291260&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934610	104132812		CHEMBL154986			C03834	ZINC27630606	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645031	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC(O)=O)n(nc1C(=O)NCc1ccc(C)cc1)-c1ccc(F)cc1	InChI=1S/C28H34FN3O5/c1-17(2)26-24(13-12-22(33)14-23(34)15-25(35)36)32(21-10-8-20(29)9-11-21)31-27(26)28(37)30-16-19-6-4-18(3)5-7-19/h4-11,17,22-23,33-34H,12-16H2,1-3H3,(H,30,37)(H,35,36)/t22-,23-/m1/s1	LRVVTOGAGAXSRZ-DHIUTWEWSA-N	18425	(3R,5R)-7-[1-(4-fluorophenyl)-3-{[(4-methylphenyl)methyl]carbamoyl}-4-(propan-2-yl)-1H-pyrazol-5-yl]-3,5-dihydroxyheptanoic acid::pyrazole, 3f	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18425&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			11562549	46518500					C03834	ZINC14968008	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645032	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)N(C)S(C)(=O)=O	InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17-/m1/s1	BPRHUIZQVSMCRT-VEUZHWNKSA-N	18372	(3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid::CHEMBL1496::Ros::Rosuvastatin::US9102656, Rosuvastatin ::ZD4522	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.1							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=18372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=18372&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search		1HWL	446157	46518448	38545	CHEMBL1496	DB01098	2989	C03834	ZINC01535101	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645033	Cc1c(nc(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(=O)NCc1ccccc1	InChI=1S/C25H28FN3O5/c1-16-23(25(34)27-15-17-5-3-2-4-6-17)28-24(18-7-9-19(26)10-8-18)29(16)12-11-20(30)13-21(31)14-22(32)33/h2-10,20-21,30-31H,11-15H2,1H3,(H,27,34)(H,32,33)/p-1/t20-,21-/m1/s1	AUUWRGQLAJVLPA-NHCUHLMSSA-M	50346274	CHEMBL1782548::sodium(3R,5R)-7-(4-(benzylcarbamoyl)-2-(4-fluorophenyl)-5-methyl-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 94							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346274&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932238	131349205		CHEMBL1782548			C03834	ZINC71294977	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645034	CCc1c(nc(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(=O)NCc1ccccc1	InChI=1S/C26H30FN3O5/c1-2-22-24(26(35)28-16-17-6-4-3-5-7-17)29-25(18-8-10-19(27)11-9-18)30(22)13-12-20(31)14-21(32)15-23(33)34/h3-11,20-21,31-32H,2,12-16H2,1H3,(H,28,35)(H,33,34)/p-1/t20-,21-/m1/s1	BVUZAZZCCUVFHT-NHCUHLMSSA-M	50346275	CHEMBL1782547::sodium(3R,5R)-7-(4-(benzylcarbamoyl)-5-ethyl-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 123							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346275&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932239	131349206		CHEMBL1782547			C03834	ZINC71295471	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645035	CCCc1c(nc(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(=O)NCc1ccccc1	InChI=1S/C27H32FN3O5/c1-2-6-23-25(27(36)29-17-18-7-4-3-5-8-18)30-26(19-9-11-20(28)12-10-19)31(23)14-13-21(32)15-22(33)16-24(34)35/h3-5,7-12,21-22,32-33H,2,6,13-17H2,1H3,(H,29,36)(H,34,35)/p-1/t21-,22-/m1/s1	JIVQMHYHCHVBAN-FGZHOGPDSA-M	50346276	CHEMBL1782549::sodium(3R,5R)-7-(4-(benzylcarbamoyl)-2-(4-fluorophenyl)-5-propyl-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 26							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346276	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346276&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932240	131349207		CHEMBL1782549			C03834	ZINC35974898	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645036	CC(C)c1c(nc(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(=O)NCc1ccccc1	InChI=1S/C27H32FN3O5/c1-17(2)25-24(27(36)29-16-18-6-4-3-5-7-18)30-26(19-8-10-20(28)11-9-19)31(25)13-12-21(32)14-22(33)15-23(34)35/h3-11,17,21-22,32-33H,12-16H2,1-2H3,(H,29,36)(H,34,35)/p-1/t21-,22-/m1/s1	ATGOOVTXNDYCBK-FGZHOGPDSA-M	50346277	CHEMBL1782550::sodium(3R,5R)-7-(4-(benzylcarbamoyl)-2-(4-fluorophenyl)-5-isopropyl-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.9							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346277&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44629670	131349208		CHEMBL1782550			C03834	ZINC11687503	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645037	O[C@H](CCn1c(nc(C(=O)NCc2ccccc2)c1C1CC1)-c1ccc(F)cc1)C[C@@H](O)CC([O-])=O	InChI=1S/C27H30FN3O5/c28-20-10-8-19(9-11-20)26-30-24(27(36)29-16-17-4-2-1-3-5-17)25(18-6-7-18)31(26)13-12-21(32)14-22(33)15-23(34)35/h1-5,8-11,18,21-22,32-33H,6-7,12-16H2,(H,29,36)(H,34,35)/p-1/t21-,22-/m1/s1	WHZKCTOICUQDKT-FGZHOGPDSA-M	50346278	CHEMBL1782551::sodium(3R,5R)-7-(4-(benzylcarbamoyl)-5-cyclopropyl-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.4							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346278	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346278&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932241	131349209		CHEMBL1782551			C03834	ZINC11686188	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645038	Cc1ccc(CNC(=O)c2nc(-c3ccc(F)cc3)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C2CC2)cc1	InChI=1S/C28H32FN3O5/c1-17-2-4-18(5-3-17)16-30-28(37)25-26(19-6-7-19)32(13-12-22(33)14-23(34)15-24(35)36)27(31-25)20-8-10-21(29)11-9-20/h2-5,8-11,19,22-23,33-34H,6-7,12-16H2,1H3,(H,30,37)(H,35,36)/p-1/t22-,23-/m1/s1	FLDKOBFFVNHKDV-DHIUTWEWSA-M	50346279	CHEMBL1782552::sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-4-(4-methylbenzylcarbamoyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.7							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346279&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932242	131349210		CHEMBL1782552			C03834	ZINC35335288	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645039	Cc1cccc(CNC(=O)c2nc(-c3ccc(F)cc3)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C2CC2)c1	InChI=1S/C28H32FN3O5/c1-17-3-2-4-18(13-17)16-30-28(37)25-26(19-5-6-19)32(12-11-22(33)14-23(34)15-24(35)36)27(31-25)20-7-9-21(29)10-8-20/h2-4,7-10,13,19,22-23,33-34H,5-6,11-12,14-16H2,1H3,(H,30,37)(H,35,36)/p-1/t22-,23-/m1/s1	UQBCYNDLQBAWMG-DHIUTWEWSA-M	50346280	CHEMBL1782553::sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-4-(3-methylbenzylcarbamoyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.2							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346280&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932243	131349211		CHEMBL1782553			C03834	ZINC71295473	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645040	Cc1ccccc1CNC(=O)c1nc(-c2ccc(F)cc2)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1C1CC1	InChI=1S/C28H32FN3O5/c1-17-4-2-3-5-20(17)16-30-28(37)25-26(18-6-7-18)32(13-12-22(33)14-23(34)15-24(35)36)27(31-25)19-8-10-21(29)11-9-19/h2-5,8-11,18,22-23,33-34H,6-7,12-16H2,1H3,(H,30,37)(H,35,36)/p-1/t22-,23-/m1/s1	GWUOIDODGYKLIT-DHIUTWEWSA-M	50346281	CHEMBL1782554::sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-4-(2-methylbenzylcarbamoyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.9							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346281&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932244	131349212		CHEMBL1782554			C03834	ZINC71294210	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645041	COc1ccc(CNC(=O)c2nc(-c3ccc(F)cc3)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C2CC2)cc1	InChI=1S/C28H32FN3O6/c1-38-23-10-2-17(3-11-23)16-30-28(37)25-26(18-4-5-18)32(13-12-21(33)14-22(34)15-24(35)36)27(31-25)19-6-8-20(29)9-7-19/h2-3,6-11,18,21-22,33-34H,4-5,12-16H2,1H3,(H,30,37)(H,35,36)/p-1/t21-,22-/m1/s1	KXFWXSJMVLPHDA-FGZHOGPDSA-M	50346282	CHEMBL1782555::sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-4-(4-methoxybenzylcarbamoyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.2							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346282&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932245	131349213		CHEMBL1782555			C03834	ZINC11687602	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645042	COc1cccc(CNC(=O)c2nc(-c3ccc(F)cc3)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C2CC2)c1	InChI=1S/C28H32FN3O6/c1-38-23-4-2-3-17(13-23)16-30-28(37)25-26(18-5-6-18)32(12-11-21(33)14-22(34)15-24(35)36)27(31-25)19-7-9-20(29)10-8-19/h2-4,7-10,13,18,21-22,33-34H,5-6,11-12,14-16H2,1H3,(H,30,37)(H,35,36)/p-1/t21-,22-/m1/s1	XSSRLMPNWMRVQH-FGZHOGPDSA-M	50346283	CHEMBL1782556::sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-4-(3-methoxybenzylcarbamoyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.2							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346283&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932246	131349214		CHEMBL1782556			C03834	ZINC71295644	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645043	COc1ccccc1CNC(=O)c1nc(-c2ccc(F)cc2)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c1C1CC1	InChI=1S/C28H32FN3O6/c1-38-23-5-3-2-4-19(23)16-30-28(37)25-26(17-6-7-17)32(13-12-21(33)14-22(34)15-24(35)36)27(31-25)18-8-10-20(29)11-9-18/h2-5,8-11,17,21-22,33-34H,6-7,12-16H2,1H3,(H,30,37)(H,35,36)/p-1/t21-,22-/m1/s1	SOEKQCPJQWCKDC-FGZHOGPDSA-M	50346284	CHEMBL1782557::sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-4-(2-methoxybenzylcarbamoyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346284&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932247	131349215		CHEMBL1782557			C03834	ZINC71281342	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645044	O[C@H](CCn1c(nc(C(=O)NCc2ccc(F)cc2)c1C1CC1)-c1ccc(F)cc1)C[C@@H](O)CC([O-])=O	InChI=1S/C27H29F2N3O5/c28-19-7-1-16(2-8-19)15-30-27(37)24-25(17-3-4-17)32(12-11-21(33)13-22(34)14-23(35)36)26(31-24)18-5-9-20(29)10-6-18/h1-2,5-10,17,21-22,33-34H,3-4,11-15H2,(H,30,37)(H,35,36)/p-1/t21-,22-/m1/s1	IXGFWPSQCUETRM-FGZHOGPDSA-M	50346285	CHEMBL1782558::sodium(3R,5R)-7-(5-cyclopropyl-4-(4-fluorobenzylcarbamoyl)-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.4							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346285&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932248	131349216		CHEMBL1782558			C03834	ZINC71295039	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645045	O[C@H](CCn1c(nc(C(=O)NCc2cccc(F)c2)c1C1CC1)-c1ccc(F)cc1)C[C@@H](O)CC([O-])=O	InChI=1S/C27H29F2N3O5/c28-19-8-6-18(7-9-19)26-31-24(27(37)30-15-16-2-1-3-20(29)12-16)25(17-4-5-17)32(26)11-10-21(33)13-22(34)14-23(35)36/h1-3,6-9,12,17,21-22,33-34H,4-5,10-11,13-15H2,(H,30,37)(H,35,36)/p-1/t21-,22-/m1/s1	MTCOKKTVNVFMCS-FGZHOGPDSA-M	50346286	CHEMBL1782559::sodium(3R,5R)-7-(5-cyclopropyl-4-(3-fluorobenzylcarbamoyl)-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.2							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346286&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932249	131349217		CHEMBL1782559			C03834	ZINC71295530	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645046	O[C@H](CCn1c(nc(C(=O)NCc2ccccc2F)c1C1CC1)-c1ccc(F)cc1)C[C@@H](O)CC([O-])=O	InChI=1S/C27H29F2N3O5/c28-19-9-7-17(8-10-19)26-31-24(27(37)30-15-18-3-1-2-4-22(18)29)25(16-5-6-16)32(26)12-11-20(33)13-21(34)14-23(35)36/h1-4,7-10,16,20-21,33-34H,5-6,11-15H2,(H,30,37)(H,35,36)/p-1/t20-,21-/m1/s1	QMFVRHLMRPHFFE-NHCUHLMSSA-M	50346287	CHEMBL1782062::sodium(3R,5R)-7-(5-cyclopropyl-4-(2-fluorobenzylcarbamoyl)-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.5							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346287&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932250	131349218		CHEMBL1782062			C03834	ZINC71281486	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645047	O[C@H](CCn1c(nc(C(=O)NCc2ccc(F)c(F)c2)c1C1CC1)-c1ccc(F)cc1)C[C@@H](O)CC([O-])=O	InChI=1S/C27H28F3N3O5/c28-18-6-4-17(5-7-18)26-32-24(27(38)31-14-15-1-8-21(29)22(30)11-15)25(16-2-3-16)33(26)10-9-19(34)12-20(35)13-23(36)37/h1,4-8,11,16,19-20,34-35H,2-3,9-10,12-14H2,(H,31,38)(H,36,37)/p-1/t19-,20-/m1/s1	WEDGEZDERPWKAN-WOJBJXKFSA-M	50346288	CHEMBL1782560::sodium(3R,5R)-7-(5-cyclopropyl-4-(3,4-difluorobenzylcarbamoyl)-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.2							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346288&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932251	131349219		CHEMBL1782560			C03834	ZINC71295143	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645048	O[C@H](CCn1c(nc(C(=O)NCc2ccc(F)cc2F)c1C1CC1)-c1ccc(F)cc1)C[C@@H](O)CC([O-])=O	InChI=1S/C27H28F3N3O5/c28-18-6-3-16(4-7-18)26-32-24(27(38)31-14-17-5-8-19(29)11-22(17)30)25(15-1-2-15)33(26)10-9-20(34)12-21(35)13-23(36)37/h3-8,11,15,20-21,34-35H,1-2,9-10,12-14H2,(H,31,38)(H,36,37)/p-1/t20-,21-/m1/s1	ALMIEUFUHIWSJC-NHCUHLMSSA-M	50346289	CHEMBL1782561::sodium(3R,5R)-7-(5-cyclopropyl-4-(2,4-difluorobenzylcarbamoyl)-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.2							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346289&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932252	131349220		CHEMBL1782561			C03834	ZINC71294969	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645049	Cc1ccc(CNC(=O)c2nc(-c3ccc(F)cc3)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C2CC2)cc1F	InChI=1S/C28H31F2N3O5/c1-16-2-3-17(12-23(16)30)15-31-28(38)25-26(18-4-5-18)33(11-10-21(34)13-22(35)14-24(36)37)27(32-25)19-6-8-20(29)9-7-19/h2-3,6-9,12,18,21-22,34-35H,4-5,10-11,13-15H2,1H3,(H,31,38)(H,36,37)/p-1/t21-,22-/m1/s1	KHZBSXDYISGQDC-FGZHOGPDSA-M	50346290	CHEMBL1782562::sodium(3R,5R)-7-(5-cyclopropyl-4-(3-fluoro-4-methylbenzylcarbamoyl)-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.1							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346290&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932253	131349221		CHEMBL1782562			C03834	ZINC71281272	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645050	COc1ccc(CNC(=O)c2nc(-c3ccc(F)cc3)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C2CC2)cc1F	InChI=1S/C28H31F2N3O6/c1-39-23-9-2-16(12-22(23)30)15-31-28(38)25-26(17-3-4-17)33(11-10-20(34)13-21(35)14-24(36)37)27(32-25)18-5-7-19(29)8-6-18/h2,5-9,12,17,20-21,34-35H,3-4,10-11,13-15H2,1H3,(H,31,38)(H,36,37)/p-1/t20-,21-/m1/s1	PFQZVZLGFDDIJU-NHCUHLMSSA-M	50346291	CHEMBL1782563::sodium(3R,5R)-7-(5-cyclopropyl-4-(3-fluoro-4-methoxybenzylcarbamoyl)-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3.7							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346291&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932254	131349222		CHEMBL1782563			C03834	ZINC71280723	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645051	NC(=O)c1ccc(CNC(=O)c2nc(-c3ccc(F)cc3)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C2CC2)cc1	InChI=1S/C28H31FN4O6/c29-20-9-7-19(8-10-20)27-32-24(28(39)31-15-16-1-3-18(4-2-16)26(30)38)25(17-5-6-17)33(27)12-11-21(34)13-22(35)14-23(36)37/h1-4,7-10,17,21-22,34-35H,5-6,11-15H2,(H2,30,38)(H,31,39)(H,36,37)/p-1/t21-,22-/m1/s1	CGPOMNYIDPSXAA-FGZHOGPDSA-M	50346292	CHEMBL1782564::sodium(3R,5R)-7-(4-(4-carbamoylbenzylcarbamoyl)-5-cyclopropyl-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.2							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346292&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932255	131349223		CHEMBL1782564			C03834	ZINC71295204	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50645052	CN(C)S(=O)(=O)c1ccc(CNC(=O)c2nc(-c3ccc(F)cc3)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C2CC2)cc1	InChI=1S/C29H35FN4O7S/c1-33(2)42(40,41)24-11-3-18(4-12-24)17-31-29(39)26-27(19-5-6-19)34(14-13-22(35)15-23(36)16-25(37)38)28(32-26)20-7-9-21(30)10-8-20/h3-4,7-12,19,22-23,35-36H,5-6,13-17H2,1-2H3,(H,31,39)(H,37,38)/p-1/t22-,23-/m1/s1	BBKCAKPNCLOJQV-DHIUTWEWSA-M	50346293	CHEMBL1782565::sodium(3R,5R)-7-(5-cyclopropyl-4-(4-(N,N-dimethylsulfamoyl)benzylcarbamoyl)-2-(4-fluorophenyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.9							ChEMBL	10.1016/j.bmcl.2010.11.103	10.7270/Q2H995J1	21183342			Pfefferkorn, JA; Litchfield, J; Hutchings, R; Cheng, XM; Larsen, SD; Auerbach, B; Bush, MR; Lee, C; Erasga, N; Bowles, DM; Boyles, DC; Lu, G; Sekerke, C; Askew, V; Hanselman, JC; Dillon, L; Lin, Z; Robertson, A; Olsen, K; Boustany, C; Atkinson, K; Goosen, TC; Sahasrabudhe, V; Chupka, J; Duignan, DB; Feng, B; Scialis, R; Kimoto, E; Bi, YA; Lai, Y; El-Kattan, A; Bakker-Arkema, R; Barclay, P; Kindt, E; Le, V; Mandema, JW; Milad, M; Tait, BD; Kennedy, R; Trivedi, BK; Kowala, M	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346293&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91932256	131349224		CHEMBL1782565			C03834	ZINC71295006	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756552	[Na+].CC(C)c1c(Br)c(Br)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O	InChI=1S/C20H24Br2FNO4/c1-11(2)19-17(21)18(22)20(12-3-5-13(23)6-4-12)24(19)8-7-14(25)9-15(26)10-16(27)28/h3-6,11,14-15,25-26H,7-10H2,1-2H3,(H,27,28)/p-1/t14?,15-/m1/s1	XKACIQXLWLWJBV-YSSOQSIOSA-M	50011203	CHEMBL3349880::Sodium; 7-[3,4-dibromo-2-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 26							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011203	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011203&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23689273	103923838		CHEMBL3349880CHEMBL143143				ZINC27524066	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756553	[Na+].CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C27H28FNO4.Na/c1-17(2)27-23(13-12-21(30)14-22(31)15-26(32)33)24(18-8-10-20(28)11-9-18)16-25(29-27)19-6-4-3-5-7-19;/h3-13,16-17,21-22,30-31H,14-15H2,1-2H3,(H,32,33);/q;+1/p-1/b13-12+;/t21-,22-;/m1./s1	HKKJZCXEWPOQOG-AJOFXCDPSA-M	50011204	CHEMBL2368094::Sodium; 7-[4-(4-fluoro-phenyl)-2-isopropyl-6-phenyl-pyridin-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011204	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011204&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23662198	103923839		CHEMBL2368094				ZINC27523305	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756554	[Na+].CC(C)c1ccc(-c2ccc(C)cc2)c(-c2ccc(F)cc2)c1OC[C@@H](O)C[C@@H](O)CC([O-])=O	InChI=1S/C28H31FO5/c1-17(2)24-12-13-25(19-6-4-18(3)5-7-19)27(20-8-10-21(29)11-9-20)28(24)34-16-23(31)14-22(30)15-26(32)33/h4-13,17,22-23,30-31H,14-16H2,1-3H3,(H,32,33)/p-1/t22-,23?/m1/s1	XFEHAFSETWBAJC-WTQRLHSKSA-M	50011205	CHEMBL3349882::Sodium; 6-(4''-fluoro-4'-isopropyl-4-methyl-[1,1';2',1'']terphenyl-3'-yloxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011205	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011205&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			101590435	103923840		CHEMBL3349882CHEMBL342975				ZINC27524041	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756557	[Na+].CC(C)c1nc2ccc(Cl)cc2c(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O	InChI=1S/C25H25ClFNO4.Na/c1-14(2)25-20(9-8-18(29)12-19(30)13-23(31)32)24(15-3-6-17(27)7-4-15)21-11-16(26)5-10-22(21)28-25;/h3-11,14,18-19,29-30H,12-13H2,1-2H3,(H,31,32);/q;+1/p-1/b9-8+;/t18-,19-;/m1./s1	MHZYHYSNANGJTA-SEJJVXMHSA-M	50011207	CHEMBL2368093::Sodium; 7-[6-chloro-4-(4-fluoro-phenyl)-2-isopropyl-quinolin-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 480							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011207	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011207&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73354368	103923842		CHEMBL2368093				ZINC27524193	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756558	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC([O-])=O)[C@@H]12	InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/p-1/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1	TUZYXOIXSAXUGO-PZAWKZKUSA-M	50368146	CS-514::Eptastatin Sodium::PRAVASTATIN SODIUM::Pravachol::Pravastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 40							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368146&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24849132	160847248	8361				C01844	ZINC03798763	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756559	CC(C)n1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(-c2ccc(F)cc2)c2ccccc12	InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/p-1/b12-11+/t18-,19-/m1/s1	FJLGEFLZQAZZCD-MCBHFWOFSA-M	50368147	(+)-(3R,5S)-fluvastatin::(3R,5S)-fluvastatin::(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid::(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid::CHEMBL1078::FLUVASTATIN SODIUM::Fluvastatin::cid_23663976	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 32							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368147&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	115	1HWI,6ZU4	37888681	160847249		CHEMBL1078			C03834	ZINC01886617	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756560	CC[C@H](C)C(=O)O[C@H]1C[C@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15+,16+,18-,19?,20+,21+,23+/m1/s1	PCZOHLXUXFIOCF-XXYSXELYSA-N	50011206	2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::CHEMBL3349881	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011206	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011206&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			10644939	103923841		CHEMBL3349881CHEMBL140273				ZINC27523307	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756561	[Na+].CC(C)c1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(cc(C)[n+]1[O-])-c1ccc(F)cc1	InChI=1S/C22H26FNO5.Na/c1-13(2)22-19(9-8-17(25)11-18(26)12-21(27)28)20(10-14(3)24(22)29)15-4-6-16(23)7-5-15;/h4-10,13,17-18,25-26H,11-12H2,1-3H3,(H,27,28);/q;+1/p-1/b9-8+;/t17-,18-;/m1./s1	SSRQHYWAWGARAI-SMUJUYJDSA-M	50011208	7-[4-(4-Fluoro-phenyl)-2-isopropyl-6-methyl-1-oxy-pyridin-3-yl]-3,5-dihydroxy-hept-6-enoic acid anion::CHEMBL2368088	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9.4							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011208&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73355932	103923843		CHEMBL2368088				ZINC27524479	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756562	[Na+].CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/p-1/t26?,27-/m1/s1	XUKUURHRXDUEBC-SSYAZFEXSA-M	50011213	CHEMBL3349878::Sodium; 7-[2-(4-fluoro-phenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.5							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011213	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011213&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			23665101	103923848		CHEMBL3349878CHEMBL356308				ZINC11615926	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756565	[Na+].CC(C)c1nc(C)cc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O	InChI=1S/C22H26FNO4.Na/c1-13(2)22-19(9-8-17(25)11-18(26)12-21(27)28)20(10-14(3)24-22)15-4-6-16(23)7-5-15;/h4-10,13,17-18,25-26H,11-12H2,1-3H3,(H,27,28);/q;+1/p-1/b9-8+;/t17-,18-;/m1./s1	USDSHKXZMLJDKC-SMUJUYJDSA-M	50011211	CHEMBL2368089::Sodium; 7-[4-(4-fluoro-phenyl)-2-isopropyl-6-methyl-pyridin-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.7							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011211	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011211&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348327	103923846		CHEMBL2368089				ZINC27523807	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756566	[Na+].Cc1cc(C)c(OC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)C1CCCCCC1	InChI=1S/C21H32O5/c1-14-9-15(2)21(19(10-14)16-7-5-3-4-6-8-16)26-13-18(23)11-17(22)12-20(24)25/h9-10,16-18,22-23H,3-8,11-13H2,1-2H3,(H,24,25)/p-1/t17-,18?/m1/s1	AMEFGKQQBOIUOK-QNSVNVJESA-M	50011212	CHEMBL3349879::Sodium; 6-(2-cycloheptyl-4,6-dimethyl-phenoxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 141							ChEMBL	10.1021/jm00105a071	10.7270/Q2MS3TC4	1992149			Roth, BD; Bocan, TM; Blankley, CJ; Chucholowski, AW; Creger, PL; Creswell, MW; Ferguson, E; Newton, RS; O'Brien, P; Picard, JA	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011212&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			101590433	103923847		CHEMBL3349879CHEMBL140527				ZINC27523808	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50760780	CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C[C@@H]2C=C[C@H](C)[C@H](CC[C@H](O)C[C@H](O)CC([O-])=O)[C@@H]12	InChI=1S/C23H38O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,13-20,22,24-26H,4,7-12H2,1-3H3,(H,27,28)/p-1/t13-,14-,15-,16-,17+,18-,19-,20-,22-/m0/s1	LBMXASQKAOXFBZ-QBEVQBSPSA-M	50004776	CHEMBL323880::Sodium; 3,5-dihydroxy-7-[6-hydroxy-2-methyl-8-(2-methyl-butyryloxy)-1,2,4a,5,6,7,8,8a-octahydro-naphthalen-1-yl]-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 14							ChEMBL	10.1021/jm00096a015	10.7270/Q2HD7W9V	1527791			Bone, EA; Davidson, AH; Lewis, CN; Todd, RS	British Bio-technology Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50004776	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50004776&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928686	103918323		CHEMBL323880			C03834	ZINC27083798	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754419	Cc1ccc(cc1)C(=C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c1nnnn1C)c1ccc(C)cc1	InChI=1S/C25H28N4O4/c1-16-4-8-18(9-5-16)24(19-10-6-17(2)7-11-19)22(25-26-27-28-29(25)3)13-12-20(30)14-21(31)15-23(32)33/h4-13,20-21,30-31H,14-15H2,1-3H3,(H,32,33)/p-1/b13-12+/t20-,21-/m1/s1	NGRGCMGUZOTSSW-DDVDASKDSA-M	50014346	CHEMBL441642::Sodium; 3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-9,9-di-p-tolyl-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1300							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014346&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928889	103926368		CHEMBL441642			C03834	ZINC26821844	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754420	Cn1nnnc1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H22F2N4O4/c1-29-23(26-27-28-29)20(11-10-18(30)12-19(31)13-21(32)33)22(14-2-6-16(24)7-3-14)15-4-8-17(25)9-5-15/h2-11,18-19,30-31H,12-13H2,1H3,(H,32,33)/p-1/b11-10+/t18-,19-/m1/s1	HPFIYXJJZZWEPC-MMKWGKFASA-M	50014345	CHEMBL11804::Sodium; (E)-(3R,5S)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 43							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014345&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18647991	103926367		CHEMBL11804			C03834	ZINC03782329	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754421	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-BXMDZJJMSA-N	34168	LOVASTATIN::MLS000069585::SMR000058779::US9115116, lovastatin::US9353061, Lovastatina::cid_53232	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 27							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34168&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	803	1CQP,7KC6	53232	252616855	40303		DB00227	2739	C07074	ZINC03812841	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754422	CC(C)n1nnc(n1)C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C25H26F2N4O4/c1-15(2)31-29-25(28-30-31)22(12-11-20(32)13-21(33)14-23(34)35)24(16-3-7-18(26)8-4-16)17-5-9-19(27)10-6-17/h3-12,15,20-21,32-33H,13-14H2,1-2H3,(H,34,35)/p-1/b12-11+/t20-,21-/m1/s1	JGHCOKYARNBRTM-LKWCPCFXSA-M	50014347	CHEMBL321715::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(2-isopropyl-2H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>300000							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014347&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928890	103926369		CHEMBL321715			C03834	ZINC26818288	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754423	Cc1ccc(C(=C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c2nnnn2C)c2ccc(C)cc2C)c(C)c1	InChI=1S/C27H32N4O4/c1-16-6-9-22(18(3)12-16)26(23-10-7-17(2)13-19(23)4)24(27-28-29-30-31(27)5)11-8-20(32)14-21(33)15-25(34)35/h6-13,20-21,32-33H,14-15H2,1-5H3,(H,34,35)/p-1/b11-8+/t20-,21-/m1/s1	UUVPDWUBKWQFOU-AZHXHMFBSA-M	50014348	CHEMBL100188::Sodium; 9,9-bis-(2,4-dimethyl-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1600							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014348&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928891	103926370		CHEMBL100188			C03834	ZINC26815877	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754424	Cc1ccc(C(=C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c2nnnn2C)c2ccc(C)cc2F)c(F)c1	InChI=1S/C25H26F2N4O4/c1-14-4-7-18(21(26)10-14)24(19-8-5-15(2)11-22(19)27)20(25-28-29-30-31(25)3)9-6-16(32)12-17(33)13-23(34)35/h4-11,16-17,32-33H,12-13H2,1-3H3,(H,34,35)/p-1/b9-6+/t16-,17-/m1/s1	BQWLBHDIOOUYSS-QOCAVEGASA-M	50014349	CHEMBL328846::Sodium; 9,9-bis-(2-fluoro-4-methyl-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 580							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014349&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928892	103926371		CHEMBL328846			C03834	ZINC26750096	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754426	COc1ccc(cc1)C(=C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c1nnnn1C)c1ccc(OC)cc1	InChI=1S/C25H28N4O6/c1-29-25(26-27-28-29)22(13-8-18(30)14-19(31)15-23(32)33)24(16-4-9-20(34-2)10-5-16)17-6-11-21(35-3)12-7-17/h4-13,18-19,30-31H,14-15H2,1-3H3,(H,32,33)/p-1/b13-8+/t18-,19-/m1/s1	BOHBWBNLSHJWDA-MGHWBQQZSA-M	50014350	CHEMBL323075::Sodium; 3,5-dihydroxy-9,9-bis-(4-methoxy-phenyl)-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1400							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014350&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928893	103926372		CHEMBL323075			C03834	ZINC26816232	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754427	CC(C)n1nnnc1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C25H26F2N4O4/c1-15(2)31-25(28-29-30-31)22(12-11-20(32)13-21(33)14-23(34)35)24(16-3-7-18(26)8-4-16)17-5-9-19(27)10-6-17/h3-12,15,20-21,32-33H,13-14H2,1-2H3,(H,34,35)/p-1/b12-11+/t20-,21-/m1/s1	WQNHXIPREYUODO-LKWCPCFXSA-M	50014353	CHEMBL319739::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-isopropyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 14000							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014353&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928896	103926375		CHEMBL319739			C03834	ZINC26749977	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754429	Cn1nnc(n1)C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H22F2N4O4/c1-29-27-23(26-28-29)20(11-10-18(30)12-19(31)13-21(32)33)22(14-2-6-16(24)7-3-14)15-4-8-17(25)9-5-15/h2-11,18-19,30-31H,12-13H2,1H3,(H,32,33)/p-1/b11-10+/t18-,19-/m1/s1	VJPNGPAOORMBST-MMKWGKFASA-M	50014352	CHEMBL102468::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(2-methyl-2H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30000							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014352&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928895	103926374		CHEMBL102468			C03834	ZINC26824003	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754430	Cc1cc(C)c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)-c1ccc(F)c(C)c1	InChI=1S/C22H25FO4/c1-13-8-14(2)19(6-5-17(24)11-18(25)12-22(26)27)20(9-13)16-4-7-21(23)15(3)10-16/h4-10,17-18,24-25H,11-12H2,1-3H3,(H,26,27)/p-1/b6-5+/t17-,18-/m1/s1	UXVPXZWXYNUYFT-PJHKVULZSA-M	50014355	CHEMBL103585::Sodium; 7-(4'-fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-3,5-dihydroxy-hept-6-enoate (XU-62320)	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 52							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014355&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			22837632	103926377		CHEMBL103585			C03834	ZINC26819827	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754431	Cc1cc(F)ccc1C(=C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c1nnnn1C)c1ccc(F)cc1C	InChI=1S/C25H26F2N4O4/c1-14-10-16(26)4-7-20(14)24(21-8-5-17(27)11-15(21)2)22(25-28-29-30-31(25)3)9-6-18(32)12-19(33)13-23(34)35/h4-11,18-19,32-33H,12-13H2,1-3H3,(H,34,35)/p-1/b9-6+/t18-,19-/m1/s1	MGSJIZDEFXXIQN-DCQHUWKXSA-M	50014356	CHEMBL320666::Sodium; 9,9-bis-(4-fluoro-2-methyl-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 29							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014356&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928897	103926378		CHEMBL320666			C03834	ZINC26820679	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754432	Cn1nnnc1C(\C=C\[C@@H]1C[C@@H](O)CC(=O)O1)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H20F2N4O3/c1-29-23(26-27-28-29)20(11-10-19-12-18(30)13-21(31)32-19)22(14-2-6-16(24)7-3-14)15-4-8-17(25)9-5-15/h2-11,18-19,30H,12-13H2,1H3/b11-10+/t18-,19-/m1/s1	VIMMECPCYZXUCI-MMKWGKFASA-N	50014354	6-[4,4-Bis-(4-fluoro-phenyl)-3-(1-methyl-1H-tetrazol-5-yl)-buta-1,3-dienyl]-4-hydroxy-tetrahydro-pyran-2-one::6-[4,4-Bis-(4-fluoro-phenyl)-3-(1-methyl-1H-tetrazol-5-yl)-buta-1,3-dienyl]-4-hydroxy-tetrahydro-pyran-2-one (BMY 22089)::BMY-22089::CHEMBL60218	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 24							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014354&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			9932838	103926376		CHEMBL60218				ZINC03786396	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754433	CC(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C22H22F2O4/c1-14(2-11-19(25)12-20(26)13-21(27)28)22(15-3-7-17(23)8-4-15)16-5-9-18(24)10-6-16/h2-11,19-20,25-26H,12-13H2,1H3,(H,27,28)/p-1/b11-2+/t19-,20-/m1/s1	HFIHSHWOSGBLEQ-VPBDITOFSA-M	50014357	CHEMBL318256::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-methyl-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7900							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014357&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928898	103926379		CHEMBL318256			C03834	ZINC26752923	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754434	Cn1nnnc1\C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(/c1ccccc1)c1ccc(F)cc1	InChI=1S/C23H23FN4O4/c1-28-23(25-26-27-28)20(12-11-18(29)13-19(30)14-21(31)32)22(15-5-3-2-4-6-15)16-7-9-17(24)10-8-16/h2-12,18-19,29-30H,13-14H2,1H3,(H,31,32)/p-1/b12-11+,22-20+/t18-,19-/m1/s1	DVWJMSNCSNYDDS-HPVXQPOBSA-M	50014358	CHEMBL103192::Sodium; 9-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-9-phenyl-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 44							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014358	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014358&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928899	103926380		CHEMBL103192			C03834	ZINC26816692	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754435	O[C@H](C[C@H](O)\C=C\C(C#N)=C(c1ccc(F)cc1)c1ccc(F)cc1)CC([O-])=O	InChI=1S/C22H19F2NO4/c23-17-6-1-14(2-7-17)22(15-3-8-18(24)9-4-15)16(13-25)5-10-19(26)11-20(27)12-21(28)29/h1-10,19-20,26-27H,11-12H2,(H,28,29)/p-1/b10-5+/t19-,20-/m1/s1	SEFXAYXYMFOTKA-CTRKQEPWSA-M	50014360	CHEMBL322399::Sodium; 8-cyano-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8000							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014360&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928900	103926382		CHEMBL322399			C03834	ZINC36242997	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754438	O[C@H](C[C@H](O)C=CC(=C(c1ccc(F)cc1)c1ccc(F)cc1)c1nnn[nH]1)CC([O-])=O	InChI=1S/C22H20F2N4O4/c23-15-5-1-13(2-6-15)21(14-3-7-16(24)8-4-14)19(22-25-27-28-26-22)10-9-17(29)11-18(30)12-20(31)32/h1-10,17-18,29-30H,11-12H2,(H,31,32)(H,25,26,27,28)/p-1/t17-,18-/m1/s1	GRFDXPZTVIPIIO-QZTJIDSGSA-M	50014363	CHEMBL419542::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(5H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 330							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014363&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928903	103926385		CHEMBL419542			C03834	ZINC26818921	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754439	CCn1nnnc1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C24H24F2N4O4/c1-2-30-24(27-28-29-30)21(12-11-19(31)13-20(32)14-22(33)34)23(15-3-7-17(25)8-4-15)16-5-9-18(26)10-6-16/h3-12,19-20,31-32H,2,13-14H2,1H3,(H,33,34)/p-1/b12-11+/t19-,20-/m1/s1	XMERFHFYRWAKEF-XICOBVEKSA-M	50014362	CHEMBL103661::Sodium; 8-(1-ethyl-1H-tetrazol-5-yl)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1100							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014362&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928902	103926384		CHEMBL103661			C03834	ZINC26816875	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754440	Cn1nnnc1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccccc1)c1ccccc1	InChI=1S/C23H24N4O4/c1-27-23(24-25-26-27)20(13-12-18(28)14-19(29)15-21(30)31)22(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-13,18-19,28-29H,14-15H2,1H3,(H,30,31)/p-1/b13-12+/t18-,19-/m1/s1	FAQRMZMWVOGCTE-WTWCKAPFSA-M	50014361	CHEMBL318754::Sodium; 3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-9,9-diphenyl-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 190							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014361&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928901	103926383		CHEMBL318754			C03834	ZINC26817658	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754441	CCn1nnc(n1)C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C24H24F2N4O4/c1-2-30-28-24(27-29-30)21(12-11-19(31)13-20(32)14-22(33)34)23(15-3-7-17(25)8-4-15)16-5-9-18(26)10-6-16/h3-12,19-20,31-32H,2,13-14H2,1H3,(H,33,34)/p-1/b12-11+/t19-,20-/m1/s1	NEAHCMMTZXVNNI-XICOBVEKSA-M	50014366	CHEMBL102484::Sodium; 8-(2-ethyl-2H-tetrazol-5-yl)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 200000							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014366&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928907	103926388		CHEMBL102484			C03834	ZINC26823476	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754442	CC(C)C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C24H26F2O4/c1-15(2)22(12-11-20(27)13-21(28)14-23(29)30)24(16-3-7-18(25)8-4-16)17-5-9-19(26)10-6-17/h3-12,15,20-21,27-28H,13-14H2,1-2H3,(H,29,30)/p-1/b12-11+/t20-,21-/m1/s1	DYRNBJYPPUSCSO-LKWCPCFXSA-M	50014364	CHEMBL318102::Sodium; 8-[bis-(4-fluoro-phenyl)-methylene]-3,5-dihydroxy-9-methyl-dec-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 230							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014364&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928905	103926386		CHEMBL318102			C03834	ZINC01915959	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50754443	Cc1cc(ccc1F)C(=C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c1nnnn1C)c1ccc(F)c(C)c1	InChI=1S/C25H26F2N4O4/c1-14-10-16(4-8-21(14)26)24(17-5-9-22(27)15(2)11-17)20(25-28-29-30-31(25)3)7-6-18(32)12-19(33)13-23(34)35/h4-11,18-19,32-33H,12-13H2,1-3H3,(H,34,35)/p-1/b7-6+/t18-,19-/m1/s1	LZRZADKQIIVKBB-LXORQPIJSA-M	50014365	CHEMBL103547::Sodium; 9,9-bis-(4-fluoro-3-methyl-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 160							ChEMBL	10.1021/jm00173a013	10.7270/Q26T0N7R	2231596			Sit, SY; Parker, RA; Motoc, I; Han, W; Balasubramanian, N; Catt, JD; Brown, PJ; Harte, WE; Thompson, MD; Wright, JJ	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014365	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014365&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928906	103926387		CHEMBL103547			C03834	ZINC26816871	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756644	OC(COc1c(CCCOc2ccc(F)cc2)cc(Cl)cc1C1CCCC1)C[C@@H](O)CC([O-])=O	InChI=1S/C26H32ClFO6/c27-19-12-18(6-3-11-33-23-9-7-20(28)8-10-23)26(24(13-19)17-4-1-2-5-17)34-16-22(30)14-21(29)15-25(31)32/h7-10,12-13,17,21-22,29-30H,1-6,11,14-16H2,(H,31,32)/p-1/t21-,22?/m1/s1	SGKRQHZSMMVREF-ZMFCMNQTSA-M	50007252	CHEMBL100884::Sodium; 6-{4-chloro-2-cyclopentyl-6-[3-(4-fluoro-phenoxy)-propyl]-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007252&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928748	103920532		CHEMBL100884			C03834	ZINC26748538	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756645	OC(COc1c(Cl)cc(Cl)cc1C(F)=C1CCCCC1)C[C@@H](O)CC([O-])=O	InChI=1S/C19H23Cl2FO5/c20-12-6-15(18(22)11-4-2-1-3-5-11)19(16(21)7-12)27-10-14(24)8-13(23)9-17(25)26/h6-7,13-14,23-24H,1-5,8-10H2,(H,25,26)/p-1/t13-,14?/m1/s1	CPGOAJGOPMOMRT-KWCCSABGSA-M	50007253	CHEMBL101512::Sodium; 6-[2,4-dichloro-6-(cyclohexylidene-fluoro-methyl)-phenoxy]-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 95							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007253&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928749	103920533		CHEMBL101512			C03834	ZINC26743754	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756647	CC(C)c1cc(C(C)C)c(OCC(O)C[C@@H](O)CC([O-])=O)c(c1)-c1ccc(F)cc1	InChI=1S/C24H31FO5/c1-14(2)17-9-21(15(3)4)24(22(10-17)16-5-7-18(25)8-6-16)30-13-20(27)11-19(26)12-23(28)29/h5-10,14-15,19-20,26-27H,11-13H2,1-4H3,(H,28,29)/p-1/t19-,20?/m1/s1	GWJDCGLHTDEKGT-FIWHBWSRSA-M	50007255	CHEMBL100165::Sodium; 6-(4'-fluoro-3,5-diisopropyl-biphenyl-2-yloxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.7							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007255&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947039	103920535		CHEMBL100165			C03834	ZINC26749372	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756648	Cc1cc(C)c(OCC(O)C[C@@H](O)CC([O-])=O)c(c1)C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C27H28F2O5/c1-16-11-17(2)27(34-15-23(31)13-22(30)14-25(32)33)24(12-16)26(18-3-7-20(28)8-4-18)19-5-9-21(29)10-6-19/h3-12,22-23,26,30-31H,13-15H2,1-2H3,(H,32,33)/p-1/t22-,23?/m1/s1	RZFGGGCCEIXACO-WTQRLHSKSA-M	50007256	CHEMBL420646::Sodium; 6-{2-[bis-(4-fluoro-phenyl)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 70							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007256&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928751	103920536		CHEMBL420646			C03834	ZINC26752986	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756651	Cc1cccc(CCCOc2ccc(F)cc2)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C22H27FO6/c1-15-4-2-5-16(6-3-11-28-20-9-7-17(23)8-10-20)22(15)29-14-19(25)12-18(24)13-21(26)27/h2,4-5,7-10,18-19,24-25H,3,6,11-14H2,1H3,(H,26,27)/p-1/t18-,19?/m1/s1	ZGPUBVJGIDZISK-MRTLOADZSA-M	50007259	CHEMBL316899::Sodium; 6-{2-[3-(4-fluoro-phenoxy)-propyl]-6-methyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 250							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007259&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928753	103920539		CHEMBL316899			C03834	ZINC26748843	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756652	CC(C)c1c(CCC(O)C[C@@H](O)CC([O-])=O)c(cn1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C26H30FNO4/c1-17(2)26-23(13-12-21(29)14-22(30)15-25(31)32)24(18-8-10-19(27)11-9-18)16-28(26)20-6-4-3-5-7-20/h3-11,16-17,21-22,29-30H,12-15H2,1-2H3,(H,31,32)/p-1/t21?,22-/m1/s1	UBFHWBHHCSSZAB-FOIFJWKZSA-M	50007261	CHEMBL102091::Sodium; 7-[4-(4-fluoro-phenyl)-2-isopropyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007261&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928754	103920541		CHEMBL102091			C03834	ZINC13887133	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756654	OC(COc1cc(OCc2ccc(F)cc2)c(Cl)cc1Cl)C[C@@H](O)CC([O-])=O	InChI=1S/C19H19Cl2FO6/c20-15-7-16(21)18(28-10-14(24)5-13(23)6-19(25)26)8-17(15)27-9-11-1-3-12(22)4-2-11/h1-4,7-8,13-14,23-24H,5-6,9-10H2,(H,25,26)/p-1/t13-,14?/m1/s1	FBQYTAFBJJNRNA-KWCCSABGSA-M	50007262	CHEMBL330662::Sodium; 6-[2,4-dichloro-5-(4-fluoro-benzyloxy)-phenoxy]-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 260							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007262&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928755	103920542		CHEMBL330662			C03834	ZINC26745002	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756655	OC(COc1c(Cl)cc(Cl)cc1C(CCOc1ccc(F)cc1)c1ccc(F)cc1)C[C@@H](O)CC([O-])=O	InChI=1S/C27H26Cl2F2O6/c28-17-11-24(27(25(29)12-17)37-15-21(33)13-20(32)14-26(34)35)23(16-1-3-18(30)4-2-16)9-10-36-22-7-5-19(31)6-8-22/h1-8,11-12,20-21,23,32-33H,9-10,13-15H2,(H,34,35)/p-1/t20-,21?,23?/m1/s1	ZAZHQOBUAOBXJC-HVIUMASTSA-M	50007263	CHEMBL317576::Sodium; 6-{2,4-dichloro-6-[3-(4-fluoro-phenoxy)-1-(4-fluoro-phenyl)-propyl]-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 150							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007263&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928756	103920543		CHEMBL317576			C03834	ZINC26749149	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756656	Cc1nc2ccccc2c(-c2ccccc2)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C22H23NO5/c1-14-22(28-13-17(25)11-16(24)12-20(26)27)21(15-7-3-2-4-8-15)18-9-5-6-10-19(18)23-14/h2-10,16-17,24-25H,11-13H2,1H3,(H,26,27)/p-1/t16-,17?/m1/s1	IAIQZRIQFGXCEB-TZHYSIJRSA-M	50007265	CHEMBL102112::Sodium; 3,5-dihydroxy-6-(2-methyl-4-phenyl-quinolin-3-yloxy)-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007265&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928758	103920545		CHEMBL102112			C03834	ZINC26744850	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756657	Cc1c(OCC(O)C[C@@H](O)CC([O-])=O)c(nc2ccccc12)-c1ccc(F)cc1	InChI=1S/C22H22FNO5/c1-13-18-4-2-3-5-19(18)24-21(14-6-8-15(23)9-7-14)22(13)29-12-17(26)10-16(25)11-20(27)28/h2-9,16-17,25-26H,10-12H2,1H3,(H,27,28)/p-1/t16-,17?/m1/s1	CCRSFINJHYPQQP-TZHYSIJRSA-M	50007254	CHEMBL103139::Sodium; 6-[2-(4-fluoro-phenyl)-4-methyl-quinolin-3-yloxy]-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1000							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007254&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928750	103920534		CHEMBL103139			C03834	ZINC26817131	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756658	Cc1cc(C)c(OCC(O)C[C@@H](O)CC([O-])=O)c(c1)C(c1ccc(F)cc1)c1cccc(c1)C(F)(F)F	InChI=1S/C28H28F4O5/c1-16-10-17(2)27(37-15-23(34)13-22(33)14-25(35)36)24(11-16)26(18-6-8-21(29)9-7-18)19-4-3-5-20(12-19)28(30,31)32/h3-12,22-23,26,33-34H,13-15H2,1-2H3,(H,35,36)/p-1/t22-,23?,26?/m1/s1	HITATFSDGIRUCG-SVRAFRINSA-M	50007266	CHEMBL100694::Sodium; 6-{2-[(4-fluoro-phenyl)-(3-trifluoromethyl-phenyl)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 90							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007266&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928759	103920546		CHEMBL100694			C03834	ZINC26750448	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756661	OC(COc1c(Cl)cc(Cl)cc1-c1ccccc1)C[C@@H](O)CC([O-])=O	InChI=1S/C18H18Cl2O5/c19-12-6-15(11-4-2-1-3-5-11)18(16(20)7-12)25-10-14(22)8-13(21)9-17(23)24/h1-7,13-14,21-22H,8-10H2,(H,23,24)/p-1/t13-,14?/m1/s1	OJDAHSKQFOREMJ-KWCCSABGSA-M	50007270	CHEMBL101718::Sodium; 6-(3,5-dichloro-biphenyl-2-yloxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 190							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007270&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928763	103920550		CHEMBL101718			C03834	ZINC26745015	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756662	CC(C)c1c(OCC(O)C[C@@H](O)CC([O-])=O)c(nc2ccccc12)-c1ccc(F)cc1	InChI=1S/C24H26FNO5/c1-14(2)22-19-5-3-4-6-20(19)26-23(15-7-9-16(25)10-8-15)24(22)31-13-18(28)11-17(27)12-21(29)30/h3-10,14,17-18,27-28H,11-13H2,1-2H3,(H,29,30)/p-1/t17-,18?/m1/s1	WFJBUGLKYOMEIA-QNSVNVJESA-M	50007271	CHEMBL101497::Sodium; 6-[2-(4-fluoro-phenyl)-4-isopropyl-quinolin-3-yloxy]-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 50							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007271	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007271&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947040	103920551		CHEMBL101497			C03834	ZINC26747972	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756663	CC(C)c1cc(Sc2ccc(F)cc2)cc(-c2ccc(F)cc2)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C27H28F2O5S/c1-16(2)24-13-23(35-22-9-7-19(29)8-10-22)14-25(17-3-5-18(28)6-4-17)27(24)34-15-21(31)11-20(30)12-26(32)33/h3-10,13-14,16,20-21,30-31H,11-12,15H2,1-2H3,(H,32,33)/p-1/t20-,21?/m1/s1	UFSXOKMGOHBXIH-VQCQRNETSA-M	50007272	CHEMBL102168::Sodium; 6-[4'-fluoro-5-(4-fluoro-phenylsulfanyl)-3-isopropyl-biphenyl-2-yloxy]-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007272&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947038	103920552		CHEMBL102168			C03834	ZINC26746037	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756664	CC(C)c1cc(SC(C)(C)Sc2cc(C(C)C)c(OC[C@H](O)C[C@@H](O)CC([O-])=O)c(c2)-c2ccc(F)cc2)cc(-c2ccc(F)cc2)c1OC[C@H](O)C[C@@H](O)CC([O-])=O	InChI=1S/C45H54F2O10S2/c1-25(2)37-19-35(21-39(27-7-11-29(46)12-8-27)43(37)56-23-33(50)15-31(48)17-41(52)53)58-45(5,6)59-36-20-38(26(3)4)44(40(22-36)28-9-13-30(47)14-10-28)57-24-34(51)16-32(49)18-42(54)55/h7-14,19-22,25-26,31-34,48-51H,15-18,23-24H2,1-6H3,(H,52,53)(H,54,55)/p-2/t31-,32-,33-,34-/m1/s1	LTNUGPYCJBEGLM-YFRBGRBWSA-L	50007268	6-[4-{1-[4-[5-carboxylato-2,4-dihydroxy-(2R,4R)-pentyloxy]-3-(4-fluorophenyl)-5-isopropylphenylsulfanyl]-1-methylethylsulfanyl}-2-(4-fluorophenyl)-6-isopropylphenoxy]-3,5-dihydroxy-(3R,5R)-hexanoate;2Sodium ion::CHEMBL321076	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007268&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928761	103920548		CHEMBL321076			C03834		1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756665	Cc1cc(Cl)cc(CCCOc2ccc(Cl)cc2)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C22H26Cl2O6/c1-14-9-17(24)10-15(3-2-8-29-20-6-4-16(23)5-7-20)22(14)30-13-19(26)11-18(25)12-21(27)28/h4-7,9-10,18-19,25-26H,2-3,8,11-13H2,1H3,(H,27,28)/p-1/t18-,19?/m1/s1	CIDBDXUSGKOYRA-MRTLOADZSA-M	50007269	CHEMBL316712::Sodium; 6-{4-chloro-2-[3-(4-chloro-phenoxy)-propyl]-6-methyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 50							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007269&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928762	103920549		CHEMBL316712			C03834	ZINC26745681	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756668	CC(C)n1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(-c2ccc(F)cc2)c2ccccc12	InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/p-1/b12-11+/t18-,19-/m1/s1	FJLGEFLZQAZZCD-MCBHFWOFSA-M	50368147	(+)-(3R,5S)-fluvastatin::(3R,5S)-fluvastatin::(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid::(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid::CHEMBL1078::FLUVASTATIN SODIUM::Fluvastatin::cid_23663976	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.5							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368147&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	115	1HWI,6ZU4	37888681	160847249		CHEMBL1078			C03834	ZINC01886617	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756669	Cc1cc(C)c(OCC(O)C[C@@H](O)CC([O-])=O)c(CC2CCCCC2)c1	InChI=1S/C21H32O5/c1-14-8-15(2)21(17(9-14)10-16-6-4-3-5-7-16)26-13-19(23)11-18(22)12-20(24)25/h8-9,16,18-19,22-23H,3-7,10-13H2,1-2H3,(H,24,25)/p-1/t18-,19?/m1/s1	WFHBTYFDIZWFDG-MRTLOADZSA-M	50007273	CHEMBL99834::Sodium; 6-(2-cyclohexylmethyl-4,6-dimethyl-phenoxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007273&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928764	103920553		CHEMBL99834			C03834	ZINC26751134	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756670	CC(C)c1c(O)c(-c2ccc(F)cc2)c(C(C)C)c(OC[C@@H](O)C[C@@H](O)CC([O-])=O)c1C(C)C	InChI=1S/C27H37FO6/c1-14(2)22-23(15(3)4)27(34-13-20(30)11-19(29)12-21(31)32)24(16(5)6)25(26(22)33)17-7-9-18(28)10-8-17/h7-10,14-16,19-20,29-30,33H,11-13H2,1-6H3,(H,31,32)/p-1/t19-,20+/m1/s1	KFESYODZAQTVOQ-UXHICEINSA-M	50007277	CHEMBL177545::Sodium;6-(4'-Fluoro-6-hydroxy-2,4,5-triisopropyl-biphenyl-3-yloxy)-3,5-dihydroxy-hexanoic acid anion;Sodium acetyl	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007277&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928768	103920557		CHEMBL177545			C03834	ZINC13824735	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756672	Cc1cc(Cl)c(OCC(O)C[C@@H](O)CC([O-])=O)c(c1)C(c1ccc(F)c(C)c1)c1ccc(F)c(C)c1	InChI=1S/C28H29ClF2O5/c1-15-8-22(28(23(29)9-15)36-14-21(33)12-20(32)13-26(34)35)27(18-4-6-24(30)16(2)10-18)19-5-7-25(31)17(3)11-19/h4-11,20-21,27,32-33H,12-14H2,1-3H3,(H,34,35)/p-1/t20-,21?/m1/s1	KIFDBWNUTUGZID-VQCQRNETSA-M	50007278	CHEMBL103712::Sodium; 6-{2-[bis-(4-fluoro-3-methyl-phenyl)-methyl]-6-chloro-4-methyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 270							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007278	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007278&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928769	103920558		CHEMBL103712			C03834	ZINC26753162	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756674	Cc1cc(C)c(OCC(O)C[C@@H](O)CC([O-])=O)c(c1)C(C1CCCCC1)c1ccc(F)cc1	InChI=1S/C27H35FO5/c1-17-12-18(2)27(33-16-23(30)14-22(29)15-25(31)32)24(13-17)26(19-6-4-3-5-7-19)20-8-10-21(28)11-9-20/h8-13,19,22-23,26,29-30H,3-7,14-16H2,1-2H3,(H,31,32)/p-1/t22-,23?,26?/m1/s1	GVKPCBGAXFCUON-SVRAFRINSA-M	50007279	CHEMBL443275::Sodium; 6-{2-[cyclohexyl-(4-fluoro-phenyl)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 95							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007279&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928770	103920559		CHEMBL443275			C03834	ZINC26743748	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756675	Cc1cc(Cl)cc(CC2CCCCC2)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C20H29ClO5/c1-13-7-16(21)9-15(8-14-5-3-2-4-6-14)20(13)26-12-18(23)10-17(22)11-19(24)25/h7,9,14,17-18,22-23H,2-6,8,10-12H2,1H3,(H,24,25)/p-1/t17-,18?/m1/s1	RMWBEXIGBOJQMW-QNSVNVJESA-M	50007282	CHEMBL101662::Sodium; 6-(4-chloro-2-cyclohexylmethyl-6-methyl-phenoxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 75							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007282&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928772	103920562		CHEMBL101662			C03834	ZINC26745395	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756676	[Na+].CC(C)c1cc(-c2ccc(F)cc2)c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(n1)C(C)C	InChI=1S/C24H30FNO4.Na/c1-14(2)22-13-21(16-5-7-17(25)8-6-16)20(24(26-22)15(3)4)10-9-18(27)11-19(28)12-23(29)30;/h5-10,13-15,18-19,27-28H,11-12H2,1-4H3,(H,29,30);/q;+1/p-1/b10-9+;/t18-,19-;/m1./s1	QSBNHDKUOUVPNF-OSWQSNKQSA-M	50007281	CHEMBL2367819::Sodium; 7-[6-tert-butyl-4-(4-fluoro-phenyl)-2-isopropyl-pyridin-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007281&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73352843	103920561		CHEMBL2367819				ZINC26745360	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756677	CC(C)c1cc(SC(C)(C)Sc2cc(C(C)C)c(OCC(O)C[C@@H](O)CC([O-])=O)c(c2)-c2ccc(F)cc2)cc(c1[O-])-c1ccc(F)cc1	InChI=1S/C39H44F2O6S2/c1-22(2)32-17-30(19-34(37(32)46)24-7-11-26(40)12-8-24)48-39(5,6)49-31-18-33(23(3)4)38(35(20-31)25-9-13-27(41)14-10-25)47-21-29(43)15-28(42)16-36(44)45/h7-14,17-20,22-23,28-29,42-43,46H,15-16,21H2,1-6H3,(H,44,45)/p-2/t28-,29?/m1/s1	VDPZSEASYIIOOX-FICMROCWSA-L	50007274	CHEMBL101831::Disodiumsalt;6-{4'-Fluoro-5-[1-(4'-fluoro-6-hydroxy-5-isopropyl-biphenyl-3-ylsulfanyl)-1-methyl-ethylsulfanyl]-3-isopropyl-biphenyl-2-yloxy}-3,5-dihydroxy-hexanoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 30							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007274&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928765	103920554		CHEMBL101831			C03834	ZINC26745583	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756678	CC(c1ccc(F)cc1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C22H27FO5/c1-13-8-14(2)22(28-12-19(25)10-18(24)11-21(26)27)20(9-13)15(3)16-4-6-17(23)7-5-16/h4-9,15,18-19,24-25H,10-12H2,1-3H3,(H,26,27)/p-1/t15?,18-,19?/m1/s1	SWECUWNSOHJHCX-ZCDLSOSASA-M	50007280	CHEMBL100560::Sodium; 6-{2-[1-(4-fluoro-phenyl)-ethyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 160							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007280&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928771	103920560		CHEMBL100560			C03834	ZINC26747067	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756679	OC(COc1c(CCCOc2ccc(F)cc2)cccc1C1CCCC1)C[C@@H](O)CC([O-])=O	InChI=1S/C26H33FO6/c27-20-10-12-23(13-11-20)32-14-4-8-19-7-3-9-24(18-5-1-2-6-18)26(19)33-17-22(29)15-21(28)16-25(30)31/h3,7,9-13,18,21-22,28-29H,1-2,4-6,8,14-17H2,(H,30,31)/p-1/t21-,22?/m1/s1	YFQZTQGQVGCBDI-ZMFCMNQTSA-M	50007287	CHEMBL317726::Sodium; 6-{2-cyclopentyl-6-[3-(4-fluoro-phenoxy)-propyl]-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007287&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928774	103920566		CHEMBL317726			C03834	ZINC26748717	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756680	CC(C)c1c(O)c(C(C)C)c(-c2ccc(F)cc2)c(OCC(O)C[C@@H](O)CC([O-])=O)c1C(C)C	InChI=1S/C27H37FO6/c1-14(2)22-24(16(5)6)27(34-13-20(30)11-19(29)12-21(31)32)25(23(15(3)4)26(22)33)17-7-9-18(28)10-8-17/h7-10,14-16,19-20,29-30,33H,11-13H2,1-6H3,(H,31,32)/p-1/t19-,20?/m1/s1	CJLNTHWSOLNMNY-FIWHBWSRSA-M	50007267	CHEMBL321768::Sodium; 6-(4'-fluoro-5-hydroxy-3,4,6-triisopropyl-biphenyl-2-yloxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007267&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928760	103920547		CHEMBL321768			C03834	ZINC26817136	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756685	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-BXMDZJJMSA-N	34168	LOVASTATIN::MLS000069585::SMR000058779::US9115116, lovastatin::US9353061, Lovastatina::cid_53232	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34168&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	803	1CQP,7KC6	53232	252616855	40303		DB00227	2739	C07074	ZINC03812841	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756687	Cc1cc(Cl)cc(C(c2ccc(F)cc2)c2ccc(F)cc2)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C26H25ClF2O5/c1-15-10-18(27)11-23(26(15)34-14-22(31)12-21(30)13-24(32)33)25(16-2-6-19(28)7-3-16)17-4-8-20(29)9-5-17/h2-11,21-22,25,30-31H,12-14H2,1H3,(H,32,33)/p-1/t21-,22?/m1/s1	RGJLCDJTSHNOSR-ZMFCMNQTSA-M	50007290	CHEMBL100357::Sodium; 6-{2-[bis-(4-fluoro-phenyl)-methyl]-4-chloro-6-methyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 70							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007290&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928776	103920568		CHEMBL100357			C03834	ZINC26750438	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756688	OC(COc1c(Cl)cc(Cl)cc1C(F)(F)C1CCCCC1)C[C@@H](O)CC([O-])=O	InChI=1S/C19H24Cl2F2O5/c20-12-6-15(19(22,23)11-4-2-1-3-5-11)18(16(21)7-12)28-10-14(25)8-13(24)9-17(26)27/h6-7,11,13-14,24-25H,1-5,8-10H2,(H,26,27)/p-1/t13-,14?/m1/s1	HBEFJWHMKNJWPE-KWCCSABGSA-M	50007291	CHEMBL321713::Sodium; 6-[2,4-dichloro-6-(cyclohexyl-difluoro-methyl)-phenoxy]-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 85							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007291&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928777	103920569		CHEMBL321713			C03834	ZINC26746669	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756689	Cc1cc(C)c(OCC2C[C@@H](O)CC(=O)O2)c(c1)C(Cl)C1CCCCC1	InChI=1S/C21H29ClO4/c1-13-8-14(2)21(25-12-17-10-16(23)11-19(24)26-17)18(9-13)20(22)15-6-4-3-5-7-15/h8-9,15-17,20,23H,3-7,10-12H2,1-2H3/t16-,17?,20?/m1/s1	JEIUHLQCZMJKSE-ZRZPHAQCSA-N	50007258	6-[2-(Chloro-cyclohexyl-methyl)-4,6-dimethyl-phenoxymethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL101824	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007258&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44331886	103920538		CHEMBL101824		2967		ZINC26746663	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756692	[Na+].CC(C)c1cc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C27H28FNO4.Na/c1-17(2)24-16-25(18-6-4-3-5-7-18)29-27(19-8-10-20(28)11-9-19)23(24)13-12-21(30)14-22(31)15-26(32)33;/h3-13,16-17,21-22,30-31H,14-15H2,1-2H3,(H,32,33);/q;+1/p-1/b13-12+;/t21-,22-;/m1./s1	HDWLTLFPXAQSHX-AJOFXCDPSA-M	50007293	CHEMBL2367826::Sodium; 7-[2-(4-fluoro-phenyl)-4-isopropyl-6-phenyl-pyridin-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007293&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73351382	103920571		CHEMBL2367826				ZINC26815579	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756694	CC(C)CC(c1ccc(F)cc1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C25H33FO5/c1-15(2)9-22(18-5-7-19(26)8-6-18)23-11-16(3)10-17(4)25(23)31-14-21(28)12-20(27)13-24(29)30/h5-8,10-11,15,20-22,27-28H,9,12-14H2,1-4H3,(H,29,30)/p-1/t20-,21?,22?/m1/s1	YXCVOFSBSRBCGH-ITAUSPCMSA-M	50007292	CHEMBL101774::Sodium; 6-{2-[1-(4-fluoro-phenyl)-3-methyl-butyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 140							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007292&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928778	103920570		CHEMBL101774			C03834	ZINC26747055	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756695	Cc1cc(ccc1F)C(c1ccc(F)c(C)c1)c1cc(Cl)cc(Cl)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C27H26Cl2F2O5/c1-14-7-16(3-5-23(14)30)26(17-4-6-24(31)15(2)8-17)21-9-18(28)10-22(29)27(21)36-13-20(33)11-19(32)12-25(34)35/h3-10,19-20,26,32-33H,11-13H2,1-2H3,(H,34,35)/p-1/t19-,20?/m1/s1	VRUKSNBTMNSBFT-FIWHBWSRSA-M	50007298	CHEMBL101097::Sodium; 6-{2-[bis-(4-fluoro-3-methyl-phenyl)-methyl]-4,6-dichloro-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1000							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007298&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928780	103920575		CHEMBL101097			C03834	ZINC26745691	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756697	[Na+].O[C@H](C[C@H](O)\C=C\c1c(Cl)cc(Cl)cc1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C19H17Cl2FO4.Na/c20-12-7-17(11-1-3-13(22)4-2-11)16(18(21)8-12)6-5-14(23)9-15(24)10-19(25)26;/h1-8,14-15,23-24H,9-10H2,(H,25,26);/q;+1/p-1/b6-5+;/t14-,15-;/m1./s1	YNSCOIWHLKTBIE-IYUPQLJSSA-M	50007297	CHEMBL2367825::Sodium; 7-(3,5-dichloro-4'-fluoro-biphenyl-2-yl)-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.5							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007297	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007297&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73348310	103920574		CHEMBL2367825				ZINC26816265	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756699	CC(C)c1c(OCC(O)C[C@@H](O)CC([O-])=O)c(cc2ccccc12)C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C32H32F2O5/c1-19(2)30-27-6-4-3-5-22(27)15-28(32(30)39-18-26(36)16-25(35)17-29(37)38)31(20-7-11-23(33)12-8-20)21-9-13-24(34)14-10-21/h3-15,19,25-26,31,35-36H,16-18H2,1-2H3,(H,37,38)/p-1/t25-,26?/m1/s1	KMUHRPGZKRKKCZ-DCWQJPKNSA-M	50007285	CHEMBL317142::Sodium; 6-{3-[bis-(4-fluoro-phenyl)-methyl]-1-isopropyl-naphthalen-2-yloxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 380							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007285&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947041	103920564		CHEMBL317142			C03834	ZINC26745119	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756700	[Na+].CC(C)c1nc(cc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)C(C)(C)C	InChI=1S/C25H32FNO4.Na/c1-15(2)24-20(11-10-18(28)12-19(29)13-23(30)31)21(14-22(27-24)25(3,4)5)16-6-8-17(26)9-7-16;/h6-11,14-15,18-19,28-29H,12-13H2,1-5H3,(H,30,31);/q;+1/p-1/b11-10+;/t18-,19-;/m1./s1	UXSWIBHKASKNFS-QKPRLWPNSA-M	50007295	CHEMBL2367823::Sodium; 7-[4-(4-fluoro-phenyl)-2,6-diisopropyl-pyridin-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007295&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345273	103920573		CHEMBL2367823				ZINC26746674	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756702	Cc1c(CCC(O)C[C@@H](O)CC([O-])=O)c(cn1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C24H26FNO4/c1-16-22(12-11-20(27)13-21(28)14-24(29)30)23(17-7-9-18(25)10-8-17)15-26(16)19-5-3-2-4-6-19/h2-10,15,20-21,27-28H,11-14H2,1H3,(H,29,30)/p-1/t20?,21-/m1/s1	VEWGDVSTEWFLQL-BPGUCPLFSA-M	50007294	CHEMBL101203::Sodium; 7-[4-(4-fluoro-phenyl)-2-methyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 35							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007294&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928779	103920572		CHEMBL101203			C03834	ZINC26745840	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756705	[Na+].Cc1cc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C25H24FNO4.Na/c1-16-13-23(17-5-3-2-4-6-17)27-25(18-7-9-19(26)10-8-18)22(16)12-11-20(28)14-21(29)15-24(30)31;/h2-13,20-21,28-29H,14-15H2,1H3,(H,30,31);/q;+1/p-1/b12-11+;/t20-,21-;/m1./s1	YNQVGZUDNRAWKS-JUGDMTMFSA-M	50007300	CHEMBL2367827::Sodium; 7-[2-(4-fluoro-phenyl)-4-methyl-6-phenyl-pyridin-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 38							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007300&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			73345275	103920577		CHEMBL2367827				ZINC26750988	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756706	CC(C)c1cc(cc(-c2ccc(F)cc2)c1OCC(O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C27H28F2O5/c1-16(2)24-11-19(17-3-7-20(28)8-4-17)12-25(18-5-9-21(29)10-6-18)27(24)34-15-23(31)13-22(30)14-26(32)33/h3-12,16,22-23,30-31H,13-15H2,1-2H3,(H,32,33)/p-1/t22-,23?/m1/s1	YCVXSUKICGGQBP-WTQRLHSKSA-M	50007299	CHEMBL329307::Sodium; 6-(4,4''-difluoro-5'-isopropyl-[1,1';3',1'']terphenyl-4'-yloxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 17							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007299&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928781	103920576		CHEMBL329307			C03834	ZINC26743713	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756707	CC(C)c1cc(cc(CC2CCCCC2)c1OCC(O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C28H38O5/c1-19(2)26-15-22(21-11-7-4-8-12-21)14-23(13-20-9-5-3-6-10-20)28(26)33-18-25(30)16-24(29)17-27(31)32/h4,7-8,11-12,14-15,19-20,24-25,29-30H,3,5-6,9-10,13,16-18H2,1-2H3,(H,31,32)/p-1/t24-,25?/m1/s1	KPUVGZRDNIMEGL-IKOFQBKESA-M	50007264	CHEMBL99838::Sodium; 6-(5-cyclohexylmethyl-3-isopropyl-biphenyl-4-yloxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 400							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007264&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928757	103920544		CHEMBL99838			C03834	ZINC26751712	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756709	OC(COc1c(Cl)cc(Cl)cc1CC1CCCCC1)C[C@@H](O)CC([O-])=O	InChI=1S/C19H26Cl2O5/c20-14-7-13(6-12-4-2-1-3-5-12)19(17(21)8-14)26-11-16(23)9-15(22)10-18(24)25/h7-8,12,15-16,22-23H,1-6,9-11H2,(H,24,25)/p-1/t15-,16?/m1/s1	JFBQKTMQLRVNBD-AAFJCEBUSA-M	50007302	CHEMBL101633::Sodium; 6-(2,4-dichloro-6-cyclohexylmethyl-phenoxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 27							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007302&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928783	103920579		CHEMBL101633			C03834	ZINC26747324	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756710	CCC(C)(C)OC(=O)C(C1CCCCC1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C27H42O7/c1-6-27(4,5)34-26(32)24(19-10-8-7-9-11-19)22-13-17(2)12-18(3)25(22)33-16-21(29)14-20(28)15-23(30)31/h12-13,19-21,24,28-29H,6-11,14-16H2,1-5H3,(H,30,31)/p-1/t20-,21?,24?/m1/s1	RMQCSWXMHKVTBQ-UZGSZPBKSA-M	50007257	CHEMBL323344::Sodium; 6-{2-[cyclohexyl-(1,1-dimethyl-propoxycarbonyl)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 500							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007257&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928752	103920537		CHEMBL323344			C03834	ZINC26745157	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756712	Cc1cc(Cl)cc(CCCOc2ccc(F)cc2)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C22H26ClFO6/c1-14-9-16(23)10-15(3-2-8-29-20-6-4-17(24)5-7-20)22(14)30-13-19(26)11-18(25)12-21(27)28/h4-7,9-10,18-19,25-26H,2-3,8,11-13H2,1H3,(H,27,28)/p-1/t18-,19?/m1/s1	HOJUELIUZSUFTD-MRTLOADZSA-M	50007305	CHEMBL319983::Sodium; 6-{4-chloro-2-[3-(4-fluoro-phenoxy)-propyl]-6-methyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 80							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007305&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928784	103920581		CHEMBL319983			C03834	ZINC26752981	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756713	Cc1c(OCC(O)C[C@@H](O)CC([O-])=O)c(cc2ccccc12)C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C30H28F2O5/c1-18-26-5-3-2-4-21(26)14-27(30(18)37-17-25(34)15-24(33)16-28(35)36)29(19-6-10-22(31)11-7-19)20-8-12-23(32)13-9-20/h2-14,24-25,29,33-34H,15-17H2,1H3,(H,35,36)/p-1/t24-,25?/m1/s1	ICEDGHZZGCMRPD-IKOFQBKESA-M	50007301	CHEMBL102199::Sodium; 6-{3-[bis-(4-fluoro-phenyl)-methyl]-1-methyl-naphthalen-2-yloxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 900							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007301&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928782	103920578		CHEMBL102199			C03834	ZINC26745345	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756714	COc1ccc(cc1)C(c1ccc(F)cc1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C28H31FO6/c1-17-12-18(2)28(35-16-23(31)14-22(30)15-26(32)33)25(13-17)27(19-4-8-21(29)9-5-19)20-6-10-24(34-3)11-7-20/h4-13,22-23,27,30-31H,14-16H2,1-3H3,(H,32,33)/p-1/t22-,23?,27?/m1/s1	IEMSSGCNYIGNPI-WXFIPNSDSA-M	50007306	CHEMBL316938::Sodium; 6-{2-[(4-fluoro-phenyl)-(4-methoxy-phenyl)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007306&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928785	103920582		CHEMBL316938			C03834	ZINC26744648	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756715	CC(C)c1cc(cc(-c2ccc(F)cc2)c1OCC(O)C[C@@H](O)CC([O-])=O)C(C)(C)C	InChI=1S/C25H33FO5/c1-15(2)21-10-17(25(3,4)5)11-22(16-6-8-18(26)9-7-16)24(21)31-14-20(28)12-19(27)13-23(29)30/h6-11,15,19-20,27-28H,12-14H2,1-5H3,(H,29,30)/p-1/t19-,20?/m1/s1	VESATANJIWURSD-FIWHBWSRSA-M	50007275	CHEMBL317777::Sodium; 6-(5-tert-butyl-4'-fluoro-3-isopropyl-biphenyl-2-yloxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 400							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007275&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928766	103920555		CHEMBL317777			C03834	ZINC26743718	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50756718	OC(COc1c(Cl)cc(Cl)cc1C(=O)C1CCCCC1)C[C@@H](O)CC([O-])=O	InChI=1S/C19H24Cl2O6/c20-12-6-15(18(26)11-4-2-1-3-5-11)19(16(21)7-12)27-10-14(23)8-13(22)9-17(24)25/h6-7,11,13-14,22-23H,1-5,8-10H2,(H,24,25)/p-1/t13-,14?/m1/s1	PEXIVRSEMGWJFU-KWCCSABGSA-M	50007307	CHEMBL101806::Sodium; 6-(2,4-dichloro-6-cyclohexanecarbonyl-phenoxy)-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 190							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007307&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928786	103920583		CHEMBL101806			C03834	ZINC26745875	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50753566	O[C@@H]1C[C@@H](CCn2c(ccc2C(F)(F)F)-c2ccc(F)cc2)OC(=O)C1	InChI=1S/C18H17F4NO3/c19-12-3-1-11(2-4-12)15-5-6-16(18(20,21)22)23(15)8-7-14-9-13(24)10-17(25)26-14/h1-6,13-14,24H,7-10H2/t13-,14-/m1/s1	WWKQYHAFGOBLDP-ZIAGYGMSSA-N	50014667	6-{2-[2-(4-Fluoro-phenyl)-5-trifluoromethyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322366	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 630							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014667&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335591	103926562		CHEMBL322366				ZINC26836766	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50753569	CCC(CC)c1ccc(C(CC)CC)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H35NO3/c1-5-15(6-2)19-9-10-20(16(7-3)8-4)22(19)12-11-18-13-17(23)14-21(24)25-18/h9-10,15-18,23H,5-8,11-14H2,1-4H3/t17-,18-/m1/s1	OKNAQZCHMPMIGW-QZTJIDSGSA-N	50014666	6-{2-[2,5-Bis-(1-ethyl-propyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104221	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014666&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335627	103926561		CHEMBL104221				ZINC26837797	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50753570	Cc1cc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(F)c(C)c1	InChI=1S/C22H23FO3/c1-13-8-14(2)19(6-5-18-11-17(24)12-22(25)26-18)20(9-13)16-4-7-21(23)15(3)10-16/h4-10,17-18,24H,11-12H2,1-3H3/b6-5+/t17-,18-/m1/s1	BNIBDNOALUGLCI-PJHKVULZSA-N	50014669	6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL440891	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014669&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6439709	103926564		CHEMBL440891				ZINC06069734	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50753607	Cc1ccc(C2CC3CC2C=C3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H25NO3/c1-12-2-5-18(17-9-13-3-4-14(17)8-13)20(12)7-6-16-10-15(21)11-19(22)23-16/h2-5,13-17,21H,6-11H2,1H3/t13?,14?,15-,16-,17?/m1/s1	IHNCWQSEFKFQIZ-VHUWHVEYSA-N	50014688	6-[2-(2-Bicyclo[2.2.1]hept-5-en-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL321914	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5800							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014688&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785456	103926583		CHEMBL321914				ZINC26839261	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50753611	CC(C)(C)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H26FNO3/c1-21(2,3)19-9-8-18(14-4-6-15(22)7-5-14)23(19)11-10-17-12-16(24)13-20(25)26-17/h4-9,16-17,24H,10-13H2,1-3H3/t16-,17-/m1/s1	PMSBINLIZBHCDF-IAGOWNOFSA-N	50014686	6-{2-[2-tert-Butyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL319870	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1800							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014686&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785442	103926581		CHEMBL319870				ZINC26833587	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50753627	Cc1ccc(-c2cccc(c2)C(F)(F)F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H20F3NO3/c1-12-5-6-17(13-3-2-4-14(9-13)19(20,21)22)23(12)8-7-16-10-15(24)11-18(25)26-16/h2-6,9,15-16,24H,7-8,10-11H2,1H3/t15-,16-/m1/s1	FDQMBHADFAULHR-HZPDHXFCSA-N	50014674	4-Hydroxy-6-{2-[2-methyl-5-(3-trifluoromethyl-phenyl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL321564	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5400							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014674&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335890	103926569		CHEMBL321564				ZINC26835097	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50753636	O[C@@H]1C[C@@H](CCn2c(ccc2-c2ccc(F)cc2)C2CCC2)OC(=O)C1	InChI=1S/C21H24FNO3/c22-16-6-4-15(5-7-16)20-9-8-19(14-2-1-3-14)23(20)11-10-18-12-17(24)13-21(25)26-18/h4-9,14,17-18,24H,1-3,10-13H2/t17-,18-/m1/s1	FPDGWLPNKJTZQU-QZTJIDSGSA-N	50014704	6-{2-[2-Cyclobutyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL107746	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 17000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014704&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335584	103926599		CHEMBL107746				ZINC26837520	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50753639	Cc1ccc(-c2ccc(O)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-2-7-17(13-3-5-14(20)6-4-13)19(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,20-21H,8-11H2,1H3/t15-,16-/m1/s1	NWLCBPATGSGBMW-HZPDHXFCSA-N	50014703	4-Hydroxy-6-{2-[2-(4-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL106167	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6300							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014703&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335903	103926598		CHEMBL106167				ZINC26831868	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50753642	Cc1ccc(-c2ccc(F)cc2)n1CCC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H22FNO3/c1-13-4-9-18(14-5-7-15(20)8-6-14)21(13)10-2-3-17-11-16(22)12-19(23)24-17/h4-9,16-17,22H,2-3,10-12H2,1H3/t16-,17-/m1/s1	SNRLXLKLVVFAQQ-IAGOWNOFSA-N	50014702	6-{3-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-propyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104038	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 53000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014702&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335692	103926597		CHEMBL104038				ZINC26835884	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765835	O[C@H](C[C@H](O)\C=C\c1c2CCCC(Cc3ccc4ccccc4c3)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C31H31FN2O4/c32-24-10-12-25(13-11-24)34-29(15-14-26(35)18-27(36)19-30(37)38)28-7-3-6-23(31(28)33-34)17-20-8-9-21-4-1-2-5-22(21)16-20/h1-2,4-5,8-16,23,26-27,35-36H,3,6-7,17-19H2,(H,37,38)/p-1/b15-14+/t23?,26-,27-/m1/s1	IVTABRHLUIMRSQ-BFCSZKAISA-M	50042665	CHEMBL332812::Sodium; 7-[2-(4-fluoro-phenyl)-7-naphthalen-2-ylmethyl-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042665&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929251	103974251		CHEMBL332812			C03834	ZINC03915626	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765836	CC(C)n1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(-c2ccc(F)cc2)c2ccccc12	InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/p-1/b12-11+/t18-,19-/m1/s1	FJLGEFLZQAZZCD-MCBHFWOFSA-M	50368147	(+)-(3R,5S)-fluvastatin::(3R,5S)-fluvastatin::(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid::(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid::CHEMBL1078::FLUVASTATIN SODIUM::Fluvastatin::cid_23663976	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.5							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368147&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	115	1HWI,6ZU4	37888681	160847249		CHEMBL1078			C03834	ZINC01886617	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765837	CCC1CCCc2c1nn(c2\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C22H27FN2O4/c1-2-14-4-3-5-19-20(11-10-17(26)12-18(27)13-21(28)29)25(24-22(14)19)16-8-6-15(23)7-9-16/h6-11,14,17-18,26-27H,2-5,12-13H2,1H3,(H,28,29)/p-1/b11-10+/t14?,17-,18-/m1/s1	JBNRVGDHOGMECT-MQZAERKXSA-M	50042669	CHEMBL123601::Sodium; 7-[7-ethyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2000							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042669&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929254	103974255		CHEMBL123601			C03834	ZINC13833985	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765838	COc1ccc(CC2CCCc3c2nn(c3\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c2ccc(F)cc2)cc1	InChI=1S/C28H31FN2O5/c1-36-24-12-5-18(6-13-24)15-19-3-2-4-25-26(14-11-22(32)16-23(33)17-27(34)35)31(30-28(19)25)21-9-7-20(29)8-10-21/h5-14,19,22-23,32-33H,2-4,15-17H2,1H3,(H,34,35)/p-1/b14-11+/t19?,22-,23-/m1/s1	HWJUINLUJXIHMD-QECCAXNHSA-M	50042670	CHEMBL421080::Sodium; 7-[2-(4-fluoro-phenyl)-7-(4-methoxy-benzyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 28							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042670&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929255	103974256		CHEMBL421080			C03834	ZINC13834007	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765839	O[C@H](C[C@H](O)\C=C\c1c2CCCC(Cc3ccccc3Cl)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C27H28ClFN2O4/c28-24-7-2-1-4-17(24)14-18-5-3-6-23-25(13-12-21(32)15-22(33)16-26(34)35)31(30-27(18)23)20-10-8-19(29)9-11-20/h1-2,4,7-13,18,21-22,32-33H,3,5-6,14-16H2,(H,34,35)/p-1/b13-12+/t18?,21-,22-/m1/s1	GCJYXMHGXUDKEX-BSIBPBDJSA-M	50042671	CHEMBL332353::Sodium; 7-[7-(2-chloro-benzyl)-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 95							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042671&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929256	103974257		CHEMBL332353			C03834	ZINC13833999	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765840	COc1cccc(CC2CCCc3c2nn(c3\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c2ccc(F)cc2)c1	InChI=1S/C28H31FN2O5/c1-36-24-6-2-4-18(15-24)14-19-5-3-7-25-26(13-12-22(32)16-23(33)17-27(34)35)31(30-28(19)25)21-10-8-20(29)9-11-21/h2,4,6,8-13,15,19,22-23,32-33H,3,5,7,14,16-17H2,1H3,(H,34,35)/p-1/b13-12+/t19?,22-,23-/m1/s1	AHVBWBZOHHMLNP-LXEXWIJZSA-M	50042672	CHEMBL122815::Sodium; 7-[2-(4-fluoro-phenyl)-7-(3-methoxy-benzyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 35							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042672&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929257	103974258		CHEMBL122815			C03834	ZINC13834005	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765841	Cc1ccc(CC2CCCc3c2nn(c3\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c2ccc(F)cc2)cc1	InChI=1S/C28H31FN2O4/c1-18-5-7-19(8-6-18)15-20-3-2-4-25-26(14-13-23(32)16-24(33)17-27(34)35)31(30-28(20)25)22-11-9-21(29)10-12-22/h5-14,20,23-24,32-33H,2-4,15-17H2,1H3,(H,34,35)/p-1/b14-13+/t20?,23-,24-/m1/s1	QCQWYTORWOYABP-ZGOFBEKFSA-M	50042673	CHEMBL124354::Sodium; 7-[2-(4-fluoro-phenyl)-7-(4-methyl-benzyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 28							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042673&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929258	103974259		CHEMBL124354			C03834	ZINC13834011	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765842	O[C@H](C[C@H](O)\C=C\c1c2CCCC(Cc3ccccc3)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C27H29FN2O4/c28-20-9-11-21(12-10-20)30-25(14-13-22(31)16-23(32)17-26(33)34)24-8-4-7-19(27(24)29-30)15-18-5-2-1-3-6-18/h1-3,5-6,9-14,19,22-23,31-32H,4,7-8,15-17H2,(H,33,34)/p-1/b14-13+/t19?,22-,23-/m1/s1	PEJOOMQGCINCRC-UNKINFRTSA-M	50042674	CHEMBL331770::Sodium; 7-[7-benzyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 68							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042674&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929259	103974260		CHEMBL331770			C03834	ZINC13833997	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765843	O[C@H](C[C@H](O)\C=C\c1c2CCCC(CCc3ccccc3)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C28H31FN2O4/c29-21-11-13-22(14-12-21)31-26(16-15-23(32)17-24(33)18-27(34)35)25-8-4-7-20(28(25)30-31)10-9-19-5-2-1-3-6-19/h1-3,5-6,11-16,20,23-24,32-33H,4,7-10,17-18H2,(H,34,35)/p-1/b16-15+/t20?,23-,24-/m1/s1	IDDSQNCCGHUHHL-AJTVCJCLSA-M	50042666	CHEMBL121965::Sodium; 7-[2-(4-fluoro-phenyl)-7-phenethyl-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 540							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042666&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929252	103974252		CHEMBL121965			C03834	ZINC13834017	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765844	O[C@H](C[C@H](O)\C=C\c1c2CCCC(Cc3ccc(Cl)cc3)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C27H28ClFN2O4/c28-19-6-4-17(5-7-19)14-18-2-1-3-24-25(13-12-22(32)15-23(33)16-26(34)35)31(30-27(18)24)21-10-8-20(29)9-11-21/h4-13,18,22-23,32-33H,1-3,14-16H2,(H,34,35)/p-1/b13-12+/t18?,22-,23-/m1/s1	JUBBDBNKYZUIMU-SPQVNVBDSA-M	50042667	CHEMBL120102::Sodium; 7-[7-(4-chloro-benzyl)-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 140							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042667&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929253	103974253		CHEMBL120102			C03834	ZINC13834001	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765845	O[C@H](C[C@H](O)\C=C\c1c2CCCC(Cc3ccc(F)cc3)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C27H28F2N2O4/c28-19-6-4-17(5-7-19)14-18-2-1-3-24-25(13-12-22(32)15-23(33)16-26(34)35)31(30-27(18)24)21-10-8-20(29)9-11-21/h4-13,18,22-23,32-33H,1-3,14-16H2,(H,34,35)/p-1/b13-12+/t18?,22-,23-/m1/s1	KKLFMCMEERQJRK-SPQVNVBDSA-M	50042676	CHEMBL122607::Sodium; 7-[7-(4-fluoro-benzyl)-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 200							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042676&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929261	103974262		CHEMBL122607			C03834	ZINC13834003	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765846	O[C@H](C[C@H](O)\C=C\c1c2CCCC(Cc3cccc4ccccc34)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C31H31FN2O4/c32-23-11-13-24(14-12-23)34-29(16-15-25(35)18-26(36)19-30(37)38)28-10-4-8-22(31(28)33-34)17-21-7-3-6-20-5-1-2-9-27(20)21/h1-3,5-7,9,11-16,22,25-26,35-36H,4,8,10,17-19H2,(H,37,38)/p-1/b16-15+/t22?,25-,26-/m1/s1	OMVGOHWOVIXDSC-UMBXIZDQSA-M	50042678	CHEMBL331900::Sodium; 7-[2-(4-fluoro-phenyl)-7-naphthalen-1-ylmethyl-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 28							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042678&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929263	103974264		CHEMBL331900			C03834	ZINC13834015	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765847	O[C@H](C[C@H](O)\C=C\c1c2CCc3ccccc3-c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C24H23FN2O4/c25-16-6-8-17(9-7-16)27-22(12-10-18(28)13-19(29)14-23(30)31)21-11-5-15-3-1-2-4-20(15)24(21)26-27/h1-4,6-10,12,18-19,28-29H,5,11,13-14H2,(H,30,31)/p-1/b12-10+/t18-,19-/m1/s1	LFGIWIWBFJSKAN-KZSBCKHLSA-M	50042679	CHEMBL332243::Sodium; 7-[2-(4-fluoro-phenyl)-4,5-dihydro-2H-benzo[g]indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9400							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042679&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929264	103974265		CHEMBL332243			C03834	ZINC13834022	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765848	O[C@H](C[C@H](O)\C=C\c1c2CCCc3ccccc3-c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C25H25FN2O4/c26-17-8-10-18(11-9-17)28-23(13-12-19(29)14-20(30)15-24(31)32)22-7-3-5-16-4-1-2-6-21(16)25(22)27-28/h1-2,4,6,8-13,19-20,29-30H,3,5,7,14-15H2,(H,31,32)/p-1/b13-12+/t19-,20-/m1/s1	CCMPOFFYOLOKIE-OKLSWEBGSA-M	50042680	CHEMBL333895::Sodium; 7-[2-(4-fluoro-phenyl)-2,4,5,6-tetrahydro-1,2-diaza-benzo[e]azulen-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2600							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042680&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929265	103974266		CHEMBL333895			C03834	ZINC13834023	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765849	O[C@H](C[C@H](O)\C=C\c1c2CCCC(C\C=C\c3ccccc3)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C29H31FN2O4/c30-22-12-14-23(15-13-22)32-27(17-16-24(33)18-25(34)19-28(35)36)26-11-5-10-21(29(26)31-32)9-4-8-20-6-2-1-3-7-20/h1-4,6-8,12-17,21,24-25,33-34H,5,9-11,18-19H2,(H,35,36)/p-1/b8-4+,17-16+/t21?,24-,25-/m1/s1	QZJVEPQVGOLRDL-SJBNBVFNSA-M	50042677	CHEMBL124769::Sodium; 7-[2-(4-fluoro-phenyl)-7-(3-phenyl-allyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 82							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042677&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929262	103974263		CHEMBL124769			C03834	ZINC13834021	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765850	O[C@H](C[C@H](O)\C=C\c1c2CCCC(c2nn1-c1ccc(F)cc1)c1ccccc1)CC([O-])=O	InChI=1S/C26H27FN2O4/c27-18-9-11-19(12-10-18)29-24(14-13-20(30)15-21(31)16-25(32)33)23-8-4-7-22(26(23)28-29)17-5-2-1-3-6-17/h1-3,5-6,9-14,20-22,30-31H,4,7-8,15-16H2,(H,32,33)/p-1/b14-13+/t20-,21-,22?/m1/s1	RKYYITMQMOSWKZ-FOAMHNGPSA-M	50042663	CHEMBL339423::Sodium; 7-[2-(4-fluoro-phenyl)-7-phenyl-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2800							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042663&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929249	103974249		CHEMBL339423			C03834	ZINC13833995	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765851	COc1ccc(CC2CCCc3c2nn(c3\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c2ccc(F)cc2)cc1OC	InChI=1S/C29H33FN2O6/c1-37-26-13-6-18(15-27(26)38-2)14-19-4-3-5-24-25(12-11-22(33)16-23(34)17-28(35)36)32(31-29(19)24)21-9-7-20(30)8-10-21/h6-13,15,19,22-23,33-34H,3-5,14,16-17H2,1-2H3,(H,35,36)/p-1/b12-11+/t19?,22-,23-/m1/s1	HLXREABKMCZJRD-XFYZOEIRSA-M	50042683	CHEMBL332548::Sodium; 7-[7-(3,4-dimethoxy-benzyl)-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 320							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042683&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929267	103974269		CHEMBL332548			C03834	ZINC13834009	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765852	O[C@H](C[C@H](O)\C=C\c1c2CCCC(Cc3ccc(cc3)-c3ccccc3)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C33H33FN2O4/c34-26-13-15-27(16-14-26)36-31(18-17-28(37)20-29(38)21-32(39)40)30-8-4-7-25(33(30)35-36)19-22-9-11-24(12-10-22)23-5-2-1-3-6-23/h1-3,5-6,9-18,25,28-29,37-38H,4,7-8,19-21H2,(H,39,40)/p-1/b18-17+/t25?,28-,29-/m1/s1	LRLBHWLNEJHHLJ-CDTDMYBXSA-M	50042682	CHEMBL122674::Sodium; 7-[7-biphenyl-4-ylmethyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042682&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947034	103974268		CHEMBL122674			C03834	ZINC03915625	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765854	CC(C)(C)c1ccc(CC2CCCc3c2nn(c3\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c2ccc(F)cc2)cc1	InChI=1S/C31H37FN2O4/c1-31(2,3)22-9-7-20(8-10-22)17-21-5-4-6-27-28(16-15-25(35)18-26(36)19-29(37)38)34(33-30(21)27)24-13-11-23(32)12-14-24/h7-16,21,25-26,35-36H,4-6,17-19H2,1-3H3,(H,37,38)/p-1/b16-15+/t21?,25-,26-/m1/s1	YDUWEPGUGRYRGM-FYHGJQMBSA-M	50042681	CHEMBL123826::Sodium; 7-[7-(4-tert-butyl-benzyl)-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 14							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042681&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929266	103974267		CHEMBL123826			C03834	ZINC03915627	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765855	O[C@H](C[C@H](O)\C=C\c1c2CCCC(CCCc3ccccc3)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C29H33FN2O4/c30-22-12-14-23(15-13-22)32-27(17-16-24(33)18-25(34)19-28(35)36)26-11-5-10-21(29(26)31-32)9-4-8-20-6-2-1-3-7-20/h1-3,6-7,12-17,21,24-25,33-34H,4-5,8-11,18-19H2,(H,35,36)/p-1/b17-16+/t21?,24-,25-/m1/s1	FAHQKCBPYZOYKG-BOYIUTJOSA-M	50042664	CHEMBL121014::Sodium; 7-[2-(4-fluoro-phenyl)-7-(3-phenyl-propyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 160							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042664&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929250	103974250		CHEMBL121014			C03834	ZINC13834019	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765856	O[C@H](C[C@H](O)\C=C\c1c2CCCc2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C19H21FN2O4/c20-12-4-6-13(7-5-12)22-18(16-2-1-3-17(16)21-22)9-8-14(23)10-15(24)11-19(25)26/h4-9,14-15,23-24H,1-3,10-11H2,(H,25,26)/p-1/b9-8+/t14-,15-/m1/s1	AGKRUDSWCIOZGR-VMFRVMOISA-M	50042686	CHEMBL121601::Sodium; 7-[2-(4-fluoro-phenyl)-2,4,5,6-tetrahydro-cyclopentapyrazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 11000							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042686&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929269	103974272		CHEMBL121601			C03834	ZINC13833979	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765857	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-BXMDZJJMSA-N	34168	LOVASTATIN::MLS000069585::SMR000058779::US9115116, lovastatin::US9353061, Lovastatina::cid_53232	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 400							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34168&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	803	1CQP,7KC6	53232	252616855	40303		DB00227	2739	C07074	ZINC03812841	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765858	O[C@H](C[C@H](O)\C=C\c1c2CCCCc2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C20H23FN2O4/c21-13-5-7-14(8-6-13)23-19(17-3-1-2-4-18(17)22-23)10-9-15(24)11-16(25)12-20(26)27/h5-10,15-16,24-25H,1-4,11-12H2,(H,26,27)/p-1/b10-9+/t15-,16-/m1/s1	PNXQUTZZXAYUOU-UETGSQEOSA-M	50042687	CHEMBL331698::Sodium; 7-[2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5300							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042687&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929270	103974273		CHEMBL331698			C03834	ZINC13833980	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765859	CC1CCCc2c1nn(c2\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C21H25FN2O4/c1-13-3-2-4-18-19(10-9-16(25)11-17(26)12-20(27)28)24(23-21(13)18)15-7-5-14(22)6-8-15/h5-10,13,16-17,25-26H,2-4,11-12H2,1H3,(H,27,28)/p-1/b10-9+/t13?,16-,17-/m1/s1	UQXRYRQZJFRMCV-KGCNZDHFSA-M	50042689	CHEMBL332108::Sodium; 7-[2-(4-fluoro-phenyl)-7-methyl-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2100							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042689&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929272	103974275		CHEMBL332108			C03834	ZINC13833983	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765860	CCCC1CCCc2c1nn(c2\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C23H29FN2O4/c1-2-4-15-5-3-6-20-21(12-11-18(27)13-19(28)14-22(29)30)26(25-23(15)20)17-9-7-16(24)8-10-17/h7-12,15,18-19,27-28H,2-6,13-14H2,1H3,(H,29,30)/p-1/b12-11+/t15?,18-,19-/m1/s1	RUFXULFIYWUOIR-JRCDRRGDSA-M	50042690	CHEMBL330953::Sodium; 7-[2-(4-fluoro-phenyl)-7-propyl-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3400							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042690&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929273	103974276		CHEMBL330953			C03834	ZINC13833987	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765861	O[C@H](C[C@H](O)\C=C\c1c2CCCCCc2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C21H25FN2O4/c22-14-6-8-15(9-7-14)24-20(18-4-2-1-3-5-19(18)23-24)11-10-16(25)12-17(26)13-21(27)28/h6-11,16-17,25-26H,1-5,12-13H2,(H,27,28)/p-1/b11-10+/t16-,17-/m1/s1	JSHPIPDFHHZPRW-XXRWXEQKSA-M	50042688	CHEMBL123245::Sodium; 7-[2-(4-fluoro-phenyl)-2,4,5,6,7,8-hexahydro-cycloheptapyrazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3600							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042688&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929271	103974274		CHEMBL123245			C03834	ZINC13833981	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765862	CC(C)c1ccc(CC2CCCc3c2nn(c3\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c2ccc(F)cc2)cc1	InChI=1S/C30H35FN2O4/c1-19(2)21-8-6-20(7-9-21)16-22-4-3-5-27-28(15-14-25(34)17-26(35)18-29(36)37)33(32-30(22)27)24-12-10-23(31)11-13-24/h6-15,19,22,25-26,34-35H,3-5,16-18H2,1-2H3,(H,36,37)/p-1/b15-14+/t22?,25-,26-/m1/s1	HKYVZEXRHSHVEW-XEXQUGQRSA-M	50042684	CHEMBL122605::Sodium; 7-[2-(4-fluoro-phenyl)-7-(4-isopropyl-benzyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 40							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042684&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929268	103974270		CHEMBL122605			C03834	ZINC13834013	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765863	CCC(C)C1CCCc2c1nn(c2\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccc(F)cc1	InChI=1S/C24H31FN2O4/c1-3-15(2)20-5-4-6-21-22(12-11-18(28)13-19(29)14-23(30)31)27(26-24(20)21)17-9-7-16(25)8-10-17/h7-12,15,18-20,28-29H,3-6,13-14H2,1-2H3,(H,30,31)/p-1/b12-11+/t15?,18-,19-,20?/m1/s1	DAFUDGKDVLOKKI-QLKLSRLDSA-M	50042691	CHEMBL331524::Sodium; 7-[7-sec-butyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3200							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042691&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929274	103974277		CHEMBL331524			C03834	ZINC13833991	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50765864	O[C@H](C[C@H](O)\C=C\c1c2CCCC(C3CCCCC3)c2nn1-c1ccc(F)cc1)CC([O-])=O	InChI=1S/C26H33FN2O4/c27-18-9-11-19(12-10-18)29-24(14-13-20(30)15-21(31)16-25(32)33)23-8-4-7-22(26(23)28-29)17-5-2-1-3-6-17/h9-14,17,20-22,30-31H,1-8,15-16H2,(H,32,33)/p-1/b14-13+/t20-,21-,22?/m1/s1	ZFYPCJNNCKLVNC-FOAMHNGPSA-M	50042692	CHEMBL331989::Sodium; 7-[7-cyclohexyl-2-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-indazol-3-yl]-3,5-dihydroxy-hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 8500							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042692&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929275	103974278		CHEMBL331989			C03834	ZINC13833993	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851293	COc1cccc(Sc2cc3ncc(\C=C\[C@@H]4C[C@@H](O)CC(=O)O4)c(Sc4cccc(OC)c4)c3cc2Sc2cccc(OC)c2)c1	InChI=1S/C37H33NO6S3/c1-41-25-7-4-10-29(17-25)45-34-20-32-33(21-35(34)46-30-11-5-8-26(18-30)42-2)38-22-23(13-14-28-15-24(39)16-36(40)44-28)37(32)47-31-12-6-9-27(19-31)43-3/h4-14,17-22,24,28,39H,15-16H2,1-3H3/b14-13+/t24-,28-/m1/s1	CUPGDCFLOTUZQT-XHYPSFNUSA-N	50221987	(4R,6S,E)-6-(2-(4,6,7-tris(3-methoxyphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239240	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15370							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221987&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437837	104094492		CHEMBL239240				ZINC28876064	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851294	CC(C)c1nc(nc(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)N(C)S(C)(=O)=O	InChI=1S/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/p-1/b10-9+/t16-,17-/m1/s1	BPRHUIZQVSMCRT-VEUZHWNKSA-M	50371228	Crestor::ROSUVASTATIN CALCIUM::Rosuvastatin::US9006282, Rosuvastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9030							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50371228	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50371228&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			9869776	160850329					C03834	ZINC01535101	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851295	COc1cccc(Sc2cc3ncc(\C=C\[C@@H]4C[C@@H](O)CC(=O)O4)c(Sc4cccc(OC)c4)c3cc2F)c1	InChI=1S/C30H26FNO5S2/c1-35-20-5-3-7-23(13-20)38-28-16-27-25(15-26(28)31)30(39-24-8-4-6-21(14-24)36-2)18(17-32-27)9-10-22-11-19(33)12-29(34)37-22/h3-10,13-17,19,22,33H,11-12H2,1-2H3/b10-9+/t19-,22-/m1/s1	VOXIBBRZAQRJDC-RFJNECMKSA-N	50221989	(4R,6S,E)-6-(2-(6-fluoro-4,7-bis(3-methoxyphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239881	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3640							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221989	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221989&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437833	104094494		CHEMBL239881				ZINC28876043	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851296	CC(C)c1ccc(Sc2ccc3c(Sc4ccc(cc4)C(C)C)c(\C=C\[C@@H]4C[C@@H](O)CC(=O)O4)cnc3c2)cc1	InChI=1S/C34H35NO3S2/c1-21(2)23-6-11-28(12-7-23)39-30-15-16-31-32(19-30)35-20-25(5-10-27-17-26(36)18-33(37)38-27)34(31)40-29-13-8-24(9-14-29)22(3)4/h5-16,19-22,26-27,36H,17-18H2,1-4H3/b10-5+/t26-,27-/m1/s1	RQLCBRLXFIHJBW-QTKLUSHHSA-N	50221990	(4R,6S,E)-6-(2-(4,7-bis(4-isopropylphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL391080	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15750							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221990	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221990&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437826	104094495		CHEMBL391080				ZINC28876005	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851297	O[C@H](C[C@H](O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O	InChI=1S/C25H24FNO4/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31)/p-1/b12-11+/t18-,19-/m1/s1	VGYFMXBACGZSIL-MCBHFWOFSA-M	50371229	Livalo::PITAVASTATIN CALCIUM::cid_24848419	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10550							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50371229	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50371229&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24848419	160850330	71258				C03834	ZINC01534965	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851298	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cnc2c(F)c(F)c(F)cc2c1Sc1ccc(F)cc1	InChI=1S/C22H15F4NO3S/c23-12-2-5-15(6-3-12)31-22-11(1-4-14-7-13(28)8-18(29)30-14)10-27-21-16(22)9-17(24)19(25)20(21)26/h1-6,9-10,13-14,28H,7-8H2/b4-1+/t13-,14-/m1/s1	UTEHRFLKVCTLLD-NYPSOXPFSA-N	50221992	(4R,6S,E)-4-hydroxy-6-(2-(6,7,8-trifluoro-4-(4-fluorophenylthio)quinolin-3-yl)vinyl)-tetrahydropyran-2-one::CHEMBL391280	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7930							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221992	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221992&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437830	104094497		CHEMBL391280				ZINC28876024	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851299	CC(C)c1ccc(Sc2c(\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)cnc3cc(Cl)c(F)cc23)cc1	InChI=1S/C25H23ClFNO3S/c1-14(2)15-4-7-19(8-5-15)32-25-16(3-6-18-9-17(29)10-24(30)31-18)13-28-23-12-21(26)22(27)11-20(23)25/h3-8,11-14,17-18,29H,9-10H2,1-2H3/b6-3+/t17-,18-/m1/s1	PYIOSNBMOACZFE-YNDRMARASA-N	50221994	(4R,6S,E)-6-(2-(7-chloro-6-fluoro-4-(4-isopropylphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239449	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 22050							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221994&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437828	104094499		CHEMBL239449				ZINC28876015	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851300	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O)-c1ccccc1	InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/p-1/t26-,27-/m1/s1	XUKUURHRXDUEBC-KAYWLYCHSA-M	50221993	CHEMBL393220::Calcium (betaR,deltaR)-2-(p-fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoate (1:2)::US9006282, Atorvastatin::atorvastatin calcium::calcium bis{(3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate}	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13220							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221993&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			17589822	104094498	50686	CHEMBL393220			C06834	ZINC03920719	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851301	COc1cccc(Sc2c(F)cc3c(Sc4cccc(OC)c4)c(\C=C\[C@@H]4C[C@@H](O)CC(=O)O4)cnc3c2Sc2cccc(OC)c2)c1	InChI=1S/C37H32FNO6S3/c1-42-24-7-4-10-28(17-24)46-35-22(13-14-27-15-23(40)16-33(41)45-27)21-39-34-31(35)20-32(38)36(47-29-11-5-8-25(18-29)43-2)37(34)48-30-12-6-9-26(19-30)44-3/h4-14,17-21,23,27,40H,15-16H2,1-3H3/b14-13+/t23-,27-/m1/s1	YQHJBKXOYYXRIM-ICIUZPRVSA-N	50221995	(4R,6S,E)-6-(2-(6-fluoro-4,7,8-tris(3-methoxyphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL269527	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 74550							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221995&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437840	104094500		CHEMBL269527				ZINC28876081	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851302	CC(C)c1ccc(Sc2c(\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)cnc3ccccc23)cc1	InChI=1S/C25H25NO3S/c1-16(2)17-8-11-21(12-9-17)30-25-18(15-26-23-6-4-3-5-22(23)25)7-10-20-13-19(27)14-24(28)29-20/h3-12,15-16,19-20,27H,13-14H2,1-2H3/b10-7+/t19-,20-/m1/s1	BXEXFNXNQJTATD-DSJULSIBSA-N	50221996	(4R,6S,E)-4-hydroxy-6-(2-(4-(4-isopropylphenylthio)quinolin-3-yl)vinyl)-tetrahydropyran-2-one::CHEMBL239242	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12650							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221996&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437825	104094501		CHEMBL239242				ZINC28876001	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851304	CC(C)c1ccc(Sc2cc3ncc(\C=C\[C@@H]4C[C@@H](O)CC(=O)O4)c(Sc4ccc(cc4)C(C)C)c3cc2F)cc1	InChI=1S/C34H34FNO3S2/c1-20(2)22-6-11-27(12-7-22)40-32-18-31-29(17-30(32)35)34(41-28-13-8-23(9-14-28)21(3)4)24(19-36-31)5-10-26-15-25(37)16-33(38)39-26/h5-14,17-21,25-26,37H,15-16H2,1-4H3/b10-5+/t25-,26-/m1/s1	UHVYTWNPUPUQHZ-NUTHWVABSA-N	50221998	(4R,6S,E)-6-(2-(6-fluoro-4,7-bis(4-isopropylphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL428560	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10600							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221998	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221998&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437834	104094503		CHEMBL428560				ZINC28876048	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851305	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cnc2cc(Sc3ccccc3)c(F)cc2c1Sc1ccccc1	InChI=1S/C28H22FNO3S2/c29-24-15-23-25(16-26(24)34-21-7-3-1-4-8-21)30-17-18(28(23)35-22-9-5-2-6-10-22)11-12-20-13-19(31)14-27(32)33-20/h1-12,15-17,19-20,31H,13-14H2/b12-11+/t19-,20-/m1/s1	VCHAKTOMDKELJJ-XICOBVEKSA-N	50222000	(4R,6S,E)-6-(2-(6-fluoro-4,7-bis(phenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239665	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4410							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50222000&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437831	104094505		CHEMBL239665				ZINC28876033	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851306	CC(C)c1ccc(Sc2cc3c(Sc4ccc(cc4)C(C)C)c(\C=C\[C@@H]4C[C@@H](O)CC(=O)O4)cnc3c(Sc3ccc(cc3)C(C)C)c2Sc2ccc(cc2)C(C)C)cc1	InChI=1S/C52H55NO3S4/c1-31(2)35-10-19-42(20-11-35)57-47-29-46-49(52(60-45-25-16-38(17-26-45)34(7)8)51(47)59-44-23-14-37(15-24-44)33(5)6)53-30-39(9-18-41-27-40(54)28-48(55)56-41)50(46)58-43-21-12-36(13-22-43)32(3)4/h9-26,29-34,40-41,54H,27-28H2,1-8H3/b18-9+/t40-,41-/m1/s1	KHMQQEBCBKBVEB-ILMYPJIJSA-N	50221999	(4R,6S,E)-6-(2-(4,6,7,8-tetrakis(4-isopropylphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239241	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4350							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50221999	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50221999&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437841	104094504		CHEMBL239241					1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851307	CC(C)c1ccc(Sc2c(\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)cnc3c(F)c(F)c(F)cc23)cc1	InChI=1S/C25H22F3NO3S/c1-13(2)14-4-7-18(8-5-14)33-25-15(3-6-17-9-16(30)10-21(31)32-17)12-29-24-19(25)11-20(26)22(27)23(24)28/h3-8,11-13,16-17,30H,9-10H2,1-2H3/b6-3+/t16-,17-/m1/s1	YXJISEPFIFCBNN-CTJKTKJGSA-N	50222001	(4R,6S,E)-4-hydroxy-6-(2-(6,7,8-trifluoro-4-(4-isopropylphenylthio)quinolin-3-yl)vinyl)-tetrahydropyran-2-one::CHEMBL239664	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3210							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222001	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50222001&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			24809814	104094506		CHEMBL239664				ZINC28876028	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851308	COc1cccc(Sc2c(F)cc3c(Sc4cccc(OC)c4)c(\C=C\[C@@H]4C[C@@H](O)CC(=O)O4)cnc3c2F)c1	InChI=1S/C30H25F2NO5S2/c1-36-19-5-3-7-22(13-19)39-29-17(9-10-21-11-18(34)12-26(35)38-21)16-33-28-24(29)15-25(31)30(27(28)32)40-23-8-4-6-20(14-23)37-2/h3-10,13-16,18,21,34H,11-12H2,1-2H3/b10-9+/t18-,21-/m1/s1	GPLSFDYCEUJUCJ-JTFJPCCOSA-N	50222002	(4R,6S,E)-6-(2-(6,8-difluoro-4,7-bis(3-methoxyphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL392336	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 49670							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222002	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50222002&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437835	104094507		CHEMBL392336				ZINC28876054	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851309	CC(C)c1ccc(Sc2cc3ncc(\C=C\[C@@H]4C[C@@H](O)CC(=O)O4)c(Sc4ccc(cc4)C(C)C)c3cc2Sc2ccc(cc2)C(C)C)cc1	InChI=1S/C43H45NO3S3/c1-26(2)29-8-15-35(16-9-29)48-40-23-38-39(24-41(40)49-36-17-10-30(11-18-36)27(3)4)44-25-32(7-14-34-21-33(45)22-42(46)47-34)43(38)50-37-19-12-31(13-20-37)28(5)6/h7-20,23-28,33-34,45H,21-22H2,1-6H3/b14-7+/t33-,34-/m1/s1	HESZPUZSUXGERN-RVCFWTDHSA-N	50222003	(4R,6S,E)-6-(2-(4,6,7-tris(4-isopropylphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL269299	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 14150							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222003	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50222003&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437838	104094508		CHEMBL269299				ZINC28876070	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851310	COc1cccc(Sc2c(\C=C\[C@@H]3C[C@@H](O)CC(=O)O3)cnc3cc(Cl)c(F)cc23)c1	InChI=1S/C23H19ClFNO4S/c1-29-15-3-2-4-17(9-15)31-23-13(5-6-16-7-14(27)8-22(28)30-16)12-26-21-11-19(24)20(25)10-18(21)23/h2-6,9-12,14,16,27H,7-8H2,1H3/b6-5+/t14-,16-/m1/s1	XFJAPYVRNNFBBA-QNQFUXMYSA-N	50222007	(4R,6S,E)-6-(2-(7-chloro-6-fluoro-4-(3-methoxyphenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239448	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9240							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50222007&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437827	104094512		CHEMBL239448				ZINC28876010	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851311	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cnc2c(Sc3ccc(F)cc3)c(Sc3ccc(F)cc3)c(F)cc2c1Sc1ccc(F)cc1	InChI=1S/C34H23F4NO3S3/c35-20-2-9-25(10-3-20)43-32-19(1-8-24-15-23(40)16-30(41)42-24)18-39-31-28(32)17-29(38)33(44-26-11-4-21(36)5-12-26)34(31)45-27-13-6-22(37)7-14-27/h1-14,17-18,23-24,40H,15-16H2/b8-1+/t23-,24-/m1/s1	PGIQBNBYVWDSES-OLZAAMFQSA-N	50222005	(4R,6S,E)-6-(2-(6-fluoro-4,7,8-tris(4-fluorophenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL394156	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 11940							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50222005&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437839	104094510		CHEMBL394156				ZINC28876076	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851312	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cnc2ccccc2c1Sc1ccc(F)cc1	InChI=1S/C22H18FNO3S/c23-15-6-9-18(10-7-15)28-22-14(13-24-20-4-2-1-3-19(20)22)5-8-17-11-16(25)12-21(26)27-17/h1-10,13,16-17,25H,11-12H2/b8-5+/t16-,17-/m1/s1	YGIXJECPGCHVGI-QQQVMXRDSA-N	50222006	(4R,6S,E)-6-(2-(4-(4-fluorophenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL394172	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 18560							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222006	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50222006&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437824	104094511		CHEMBL394172				ZINC28875997	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851313	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cnc2cc(Sc3ccc(F)cc3)c(F)cc2c1Sc1ccc(F)cc1	InChI=1S/C28H20F3NO3S2/c29-17-2-7-21(8-3-17)36-26-14-25-23(13-24(26)31)28(37-22-9-4-18(30)5-10-22)16(15-32-25)1-6-20-11-19(33)12-27(34)35-20/h1-10,13-15,19-20,33H,11-12H2/b6-1+/t19-,20-/m1/s1	JBBCVWKOYXNRKG-DGRSYERLSA-N	50222004	(4R,6S,E)-6-(2-(6-fluoro-4,7-bis(4-fluorophenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239666	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 38930							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222004	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50222004&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437832	104094509		CHEMBL239666				ZINC28876038	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851314	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cnc2c(F)c(F)c(F)cc2c1Sc1ccccc1	InChI=1S/C22H16F3NO3S/c23-17-10-16-21(20(25)19(17)24)26-11-12(22(16)30-15-4-2-1-3-5-15)6-7-14-8-13(27)9-18(28)29-14/h1-7,10-11,13-14,27H,8-9H2/b7-6+/t13-,14-/m1/s1	IXRHYCAJKTYFPY-JLVOYYQZSA-N	50222008	(4R,6S,E)-4-hydroxy-6-(2-(6,7,8-trifluoro-4-(phenylthio)quinolin-3-yl)vinyl)-tetrahydropyran-2-one::CHEMBL239450	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10670							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50222008&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437829	104094513		CHEMBL239450				ZINC28876019	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50851315	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1cnc2cc(Sc3ccccc3)c(Sc3ccccc3)cc2c1Sc1ccccc1	InChI=1S/C34H27NO3S3/c36-24-18-25(38-33(37)19-24)17-16-23-22-35-30-21-32(40-27-12-6-2-7-13-27)31(39-26-10-4-1-5-11-26)20-29(30)34(23)41-28-14-8-3-9-15-28/h1-17,20-22,24-25,36H,18-19H2/b17-16+/t24-,25-/m1/s1	XDNBIIPMBIHBGR-BYINGSIPSA-N	50222009	(4R,6S,E)-6-(2-(4,6,7-tris(phenylthio)quinolin-3-yl)vinyl)-4-hydroxy-tetrahydropyran-2-one::CHEMBL239239	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 32550							ChEMBL	10.1016/j.bmc.2007.08.044	10.7270/Q22R3SH6	17851082			Cai, Z; Zhou, W; Sun, L	Institute of Pharmaceutical Industry	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50222009	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50222009&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44437836	104094514		CHEMBL239239				ZINC28876059	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884437	CCC(CC)(c1ccc(F)cc1)c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)C(C)C	InChI=1S/C27H35FO4/c1-5-27(6-2,20-10-12-22(28)13-11-20)21-9-7-19(25(15-21)18(3)4)8-14-23(29)16-24(30)17-26(31)32/h7-15,18,23-24,29-30H,5-6,16-17H2,1-4H3,(H,31,32)/p-1/b14-8+/t23-,24-/m1/s1	PRTAAFRMQSHVEO-GZYSQLKFSA-M	50296073	CHEMBL562883::sodium(3R,5S,E)-7-(4-(3-(4-fluorophenyl)pentan-3-yl)-2-isopropylphenyl)-3,5-dihydroxyhept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 26000							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296073	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296073&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934330	104137604		CHEMBL562883			C03834	ZINC43009314	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884438	CCC(CC)(c1cccc(F)c1)c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)C(C)C	InChI=1S/C27H35FO4/c1-5-27(6-2,20-8-7-9-22(28)14-20)21-12-10-19(25(15-21)18(3)4)11-13-23(29)16-24(30)17-26(31)32/h7-15,18,23-24,29-30H,5-6,16-17H2,1-4H3,(H,31,32)/p-1/b13-11+/t23-,24-/m1/s1	QMPBQMYCTYCWCT-DGTKBQTJSA-M	50296074	CHEMBL557036::sodium(3R,5S,E)-7-(4-(3-(3-fluorophenyl)pentan-3-yl)-2-isopropylphenyl)-3,5-dihydroxyhept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 92000							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296074	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296074&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934331	104137605		CHEMBL557036			C03834	ZINC43021424	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884439	CCC(CC)(c1ccc(F)cc1)c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)C(C)C	InChI=1S/C27H35FO4/c1-5-27(6-2,20-10-12-22(28)13-11-20)21-9-7-19(25(15-21)18(3)4)8-14-23(29)16-24(30)17-26(31)32/h7-15,18,23-24,29-30H,5-6,16-17H2,1-4H3,(H,31,32)/p-1/b14-8+/t23-,24-/m1/s1	PRTAAFRMQSHVEO-GZYSQLKFSA-M	50296073	CHEMBL562883::sodium(3R,5S,E)-7-(4-(3-(4-fluorophenyl)pentan-3-yl)-2-isopropylphenyl)-3,5-dihydroxyhept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2200							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296073	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296073&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934330	104137604		CHEMBL562883			C03834	ZINC43009314	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884440	CCC(CC)(c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)C(C)C)c1ccccc1F	InChI=1S/C27H35FO4/c1-5-27(6-2,24-9-7-8-10-25(24)28)20-13-11-19(23(15-20)18(3)4)12-14-21(29)16-22(30)17-26(31)32/h7-15,18,21-22,29-30H,5-6,16-17H2,1-4H3,(H,31,32)/p-1/b14-12+/t21-,22-/m1/s1	XGHUUHXYQJHQGG-CUHRTYRFSA-M	50296075	CHEMBL564931::sodium(3R,5S,E)-7-(4-(3-(2-fluorophenyl)pentan-3-yl)-2-isopropylphenyl)-3,5-dihydroxyhept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7400							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296075	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296075&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934332	104137606		CHEMBL564931			C03834	ZINC43025063	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884441	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 40							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884442	CC(C)n1c(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(-c2ccc(F)cc2)c2ccccc12	InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/p-1/b12-11+/t18-,19-/m1/s1	FJLGEFLZQAZZCD-MCBHFWOFSA-M	50368147	(+)-(3R,5S)-fluvastatin::(3R,5S)-fluvastatin::(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid::(3R,5S,6E)-7-[3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid::CHEMBL1078::FLUVASTATIN SODIUM::Fluvastatin::cid_23663976	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50368147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50368147&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	115	1HWI,6ZU4	37888681	160847249		CHEMBL1078			C03834	ZINC01886617	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884443	CCC(CC)(c1ccccc1)c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)-c1ccccc1	InChI=1S/C30H34O4/c1-3-30(4-2,24-13-9-6-10-14-24)25-17-15-23(28(19-25)22-11-7-5-8-12-22)16-18-26(31)20-27(32)21-29(33)34/h5-19,26-27,31-32H,3-4,20-21H2,1-2H3,(H,33,34)/p-1/b18-16+/t26-,27-/m1/s1	VJOXGVSUZFQNAP-HNMDSZIPSA-M	50296076	CHEMBL560325::sodium(3R,5S,E)-3,5-dihydroxy-7-(5-(3-phenylpentan-3-yl)biphenyl-2-yl)hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 850							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296076	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296076&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934333	104137607		CHEMBL560325			C03834	ZINC43121671	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884444	CCC(CC)(c1ccccc1)c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)-c1ccccc1F	InChI=1S/C30H33FO4/c1-3-30(4-2,22-10-6-5-7-11-22)23-16-14-21(15-17-24(32)19-25(33)20-29(34)35)27(18-23)26-12-8-9-13-28(26)31/h5-18,24-25,32-33H,3-4,19-20H2,1-2H3,(H,34,35)/p-1/b17-15+/t24-,25-/m1/s1	IVRIJQQMQLAJLV-PJEYCIDESA-M	50296077	CHEMBL560523::sodium(3R,5S,E)-7-(2'-fluoro-5-(3-phenylpentan-3-yl)biphenyl-2-yl)-3,5-dihydroxyhept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 820							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296077	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296077&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934334	104137608		CHEMBL560523			C03834	ZINC43120594	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884445	CCC(CC)(c1ccccc1)c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)-c1cccc(F)c1	InChI=1S/C30H33FO4/c1-3-30(4-2,23-10-6-5-7-11-23)24-15-13-21(14-16-26(32)19-27(33)20-29(34)35)28(18-24)22-9-8-12-25(31)17-22/h5-18,26-27,32-33H,3-4,19-20H2,1-2H3,(H,34,35)/p-1/b16-14+/t26-,27-/m1/s1	WJLHSOZHUQVPDH-FBTBEWQISA-M	50296078	CHEMBL557852::sodium(3R,5S,E)-7-(3'-fluoro-5-(3-phenylpentan-3-yl)biphenyl-2-yl)-3,5-dihydroxyhept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1200							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296078	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296078&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934335	104137609		CHEMBL557852			C03834	ZINC43120731	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884446	CCC(CC)(c1ccccc1)c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)-c1ccc(F)cc1	InChI=1S/C30H33FO4/c1-3-30(4-2,23-8-6-5-7-9-23)24-14-10-21(13-17-26(32)19-27(33)20-29(34)35)28(18-24)22-11-15-25(31)16-12-22/h5-18,26-27,32-33H,3-4,19-20H2,1-2H3,(H,34,35)/p-1/b17-13+/t26-,27-/m1/s1	VICOOSNNZUPVHM-IGPZRPDBSA-M	50296079	CHEMBL562679::sodium(3R,5S,E)-7-(4'-fluoro-5-(3-phenylpentan-3-yl)biphenyl-2-yl)-3,5-dihydroxyhept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 150							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296079	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296079&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947033	104137610		CHEMBL562679			C03834	ZINC43074092	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50884447	CCC(CC)(c1ccccc1)c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)C(C)C	InChI=1S/C27H36O4/c1-5-27(6-2,21-10-8-7-9-11-21)22-14-12-20(25(16-22)19(3)4)13-15-23(28)17-24(29)18-26(30)31/h7-16,19,23-24,28-29H,5-6,17-18H2,1-4H3,(H,30,31)/p-1/b15-13+/t23-,24-/m1/s1	KXGCCVVMZLNEPZ-ZUYUJVNMSA-M	50296080	CHEMBL551868::sodium(3R,5S,E)-3,5-dihydroxy-7-(2-isopropyl-4-(3-phenylpentan-3-yl)phenyl)hept-6-enoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1800							ChEMBL	10.1016/j.bmcl.2009.05.100	10.7270/Q22F7PCK	19502059			Hosoda, S; Matsuda, D; Tomoda, H; Hashimoto, M; Aoyama, H; Hashimoto, Y	The University of Tokyo	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50296080	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50296080&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91934336	104137611		CHEMBL551868			C03834	ZINC43064049	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50983409	CC(C)[C@@H](O)C(=O)NCCC(=O)NCCNCC(O)CC(O)CC(O)=O	InChI=1S/C16H31N3O7/c1-10(2)15(25)16(26)19-4-3-13(22)18-6-5-17-9-12(21)7-11(20)8-14(23)24/h10-12,15,17,20-21,25H,3-9H2,1-2H3,(H,18,22)(H,19,26)(H,23,24)/t11?,12?,15-/m1/s1	WYAUEMSHEPIZPK-KOHJWAIASA-N	50391329	CHEMBL42791	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000000							ChEMBL	10.1016/S0960-894X(01)80791-5	10.7270/Q2RN392R				Gordon, E; Pluscec, J; Ciosek, C	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391329	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391329&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44289362	160870412		CHEMBL42791			C03834	ZINC29391338	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50983410	CC(C)[C@@H](O)C(=O)NCCC(=O)NCCNC(=O)C[C@@H](O)CC(O)=O	InChI=1S/C15H27N3O7/c1-9(2)14(24)15(25)18-4-3-11(20)16-5-6-17-12(21)7-10(19)8-13(22)23/h9-10,14,19,24H,3-8H2,1-2H3,(H,16,20)(H,17,21)(H,18,25)(H,22,23)/t10-,14-/m1/s1	UUMZLCBCDLRHNB-QMTHXVAHSA-N	50391330	CHEMBL42931	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000000							ChEMBL	10.1016/S0960-894X(01)80791-5	10.7270/Q2RN392R				Gordon, E; Pluscec, J; Ciosek, C	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391330&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44289378	160870413		CHEMBL42931			C03834	ZINC29392561	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50983411	CC(C)[C@@H](O)C(=O)NCCC(=O)NCCNC(=O)C[C@@](C)(O)CC(O)=O	InChI=1S/C16H29N3O7/c1-10(2)14(24)15(25)19-5-4-11(20)17-6-7-18-12(21)8-16(3,26)9-13(22)23/h10,14,24,26H,4-9H2,1-3H3,(H,17,20)(H,18,21)(H,19,25)(H,22,23)/t14-,16-/m1/s1	CJLQAUADPQDKOL-GDBMZVCRSA-N	50391331	CHEMBL44196	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>1000000							ChEMBL	10.1016/S0960-894X(01)80791-5	10.7270/Q2RN392R				Gordon, E; Pluscec, J; Ciosek, C	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50391331	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50391331&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44289399	160870414		CHEMBL44196				ZINC29389729	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50990170	Cc1ccc(-c2ccc3ccccc3c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H23NO3/c1-15-6-9-21(18-8-7-16-4-2-3-5-17(16)12-18)23(15)11-10-20-13-19(24)14-22(25)26-20/h2-9,12,19-20,24H,10-11,13-14H2,1H3/t19-,20-/m1/s1	YAGSCRJOPNSMPV-WOJBJXKFSA-N	50014696	4-Hydroxy-6-[2-(2-methyl-5-naphthalen-2-yl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL317885	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15849							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014696&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785454	103926591		CHEMBL317885				ZINC26834167	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50990174	Cc1ccc(-c2cccc(O)c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-5-6-17(13-3-2-4-14(20)9-13)19(12)8-7-16-10-15(21)11-18(22)23-16/h2-6,9,15-16,20-21H,7-8,10-11H2,1H3/t15-,16-/m1/s1	JLJGUVLGBDDOHL-HZPDHXFCSA-N	50014682	CHEMBL105654::i4-Hydroxy-6-{2-[2-(3-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014682&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335679	103926577		CHEMBL105654				ZINC26833226	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50990178	Cc1ccc(-c2ccc(F)cc2)n1-c1ccc(cc1)[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H20FNO3/c1-14-2-11-20(15-3-7-17(23)8-4-15)24(14)18-9-5-16(6-10-18)21-12-19(25)13-22(26)27-21/h2-11,19,21,25H,12-13H2,1H3/t19-,21+/m1/s1	AJEIONSXDYSIJV-CTNGQTDRSA-N	50014705	6-{4-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322874	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 19953							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014705&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335494	103926600		CHEMBL322874				ZINC26836199	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50990198	Cc1ccc(-c2ccc(Cl)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H20ClNO3/c1-12-2-7-17(13-3-5-14(19)6-4-13)20(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,21H,8-11H2,1H3/t15-,16-/m1/s1	GVJDVHXMPCFWFM-HZPDHXFCSA-N	50014677	6-{2-[2-(4-Chloro-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL323019	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3162							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014677&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335689	103926572		CHEMBL323019				ZINC26837126	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50990216	CC(C)Oc1ccccc1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C23H31NO4/c1-15(2)20-9-10-21(19-7-5-6-8-22(19)27-16(3)4)24(20)12-11-18-13-17(25)14-23(26)28-18/h5-10,15-18,25H,11-14H2,1-4H3/t17-,18-/m1/s1	STNUXLZOZDUOQU-QZTJIDSGSA-N	50014700	4-Hydroxy-6-{2-[2-(2-isopropoxy-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104184	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3162							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014700&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335684	103926595		CHEMBL104184				ZINC26834472	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50990218	Cc1ccc(C2CC3CCC2C=C3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H27NO3/c1-13-2-7-19(18-10-14-3-5-15(18)6-4-14)21(13)9-8-17-11-16(22)12-20(23)24-17/h2-3,5,7,14-18,22H,4,6,8-12H2,1H3/t14?,15?,16-,17-,18?/m1/s1	IZGLNLIZJQSJNI-PXUJOYAKSA-N	50014668	6-[2-(2-Bicyclo[2.2.2]oct-5-en-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322656	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3162							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014668&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335641	103926563		CHEMBL322656				ZINC26834181	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50990227	Cc1ccc(C2CC3CCC2CC3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H29NO3/c1-13-2-7-19(18-10-14-3-5-15(18)6-4-14)21(13)9-8-17-11-16(22)12-20(23)24-17/h2,7,14-18,22H,3-6,8-12H2,1H3/t14?,15?,16-,17-,18?/m1/s1	JLQQCFATUIPBTG-PXUJOYAKSA-N	50014698	6-[2-(2-Bicyclo[2.2.2]oct-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL265305	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2512							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014698&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335733	103926593		CHEMBL265305				ZINC26834164	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50520214	CC(C)c1nc2ccccc2c(-c2ccc(F)cc2)c1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O	InChI=1S/C25H26FNO4/c1-15(2)25-21(12-11-18(28)13-19(29)14-23(30)31)24(16-7-9-17(26)10-8-16)20-5-3-4-6-22(20)27-25/h3-12,15,18-19,28-29H,13-14H2,1-2H3,(H,30,31)/b12-11+/t18-,19-/m1/s1	HWEHUXJJTRFUKM-MCBHFWOFSA-N	50193396	CHEMBL3951152	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 19							ChEMBL	10.1021/acs.jmedchem.6b00472	10.7270/Q29G5PR8	27299736			Talele, TT	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193396&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			57494127	375076218		CHEMBL3951152			C03834		1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50520231	O[C@H](C[C@H](O)\C=C\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC(O)=O	InChI=1S/C25H24FNO4/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31)/b12-11+/t18-,19-/m1/s1	VGYFMXBACGZSIL-MCBHFWOFSA-N	86707	CAS_147511-69-1::Pitavastatin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 4.1							ChEMBL	10.1021/acs.jmedchem.6b00472	10.7270/Q29G5PR8	27299736			Talele, TT	St. John's University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=86707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=86707&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	PV9	8ECG	5282452	136352756	32020		DB08860		C03834	ZINC01534965	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
51031771	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H]([O-])CC(=O)O3)C12	InChI=1S/C24H35O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23H,5,8-9,11-13H2,1-4H3/q-1/t14-,15-,16-,18+,19+,20-,21-,23?/m0/s1	SFBIMHCBVWGFOR-YIHZSZSYSA-N	50042675	CHEMBL421436::Sodium;2-{2-[2,6-dimethyl-8-(2-methyl-butyryloxy)-1,2,6,7,8,8a-hexahydro-naphthalen-1-yl]-ethyl}-6-oxo-tetrahydro-pyran-4-olate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9.2							ChEMBL	10.1021/jm00075a024	10.7270/Q2R78FVG	8246237			Connolly, PJ; Westin, CD; Loughney, DA; Minor, LK	R. W. Johnson Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50042675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50042675&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91929260	103974261		CHEMBL421436				ZINC08681778	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50001854	Cn1nnnc1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H22F2N4O4/c1-29-23(26-27-28-29)20(11-10-18(30)12-19(31)13-21(32)33)22(14-2-6-16(24)7-3-14)15-4-8-17(25)9-5-15/h2-11,18-19,30-31H,12-13H2,1H3,(H,32,33)/p-1/b11-10+/t18-,19-/m1/s1	HPFIYXJJZZWEPC-MMKWGKFASA-M	50014345	CHEMBL11804::Sodium; (E)-(3R,5S)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 21							ChEMBL	10.1016/S0960-894X(00)80623-X	10.7270/Q2NG4QJQ				Sit, SY; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014345&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18647991	103926367		CHEMBL11804			C03834	ZINC03782329	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50001856	Cn1nnnc1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H22F2N4O4/c1-29-23(26-27-28-29)20(11-10-18(30)12-19(31)13-21(32)33)22(14-2-6-16(24)7-3-14)15-4-8-17(25)9-5-15/h2-11,18-19,30-31H,12-13H2,1H3,(H,32,33)/p-1/b11-10+/t18-,19-/m1/s1	HPFIYXJJZZWEPC-MMKWGKFASA-M	50014345	CHEMBL11804::Sodium; (E)-(3R,5S)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1800							ChEMBL	10.1016/S0960-894X(00)80623-X	10.7270/Q2NG4QJQ				Sit, SY; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014345&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18647991	103926367		CHEMBL11804			C03834	ZINC03782329	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50464426	Cn1nnnc1C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C(c1ccc(F)cc1)c1ccc(F)cc1	InChI=1S/C23H22F2N4O4/c1-29-23(26-27-28-29)20(11-10-18(30)12-19(31)13-21(32)33)22(14-2-6-16(24)7-3-14)15-4-8-17(25)9-5-15/h2-11,18-19,30-31H,12-13H2,1H3,(H,32,33)/p-1/b11-10+/t18-,19-/m1/s1	HPFIYXJJZZWEPC-MMKWGKFASA-M	50014345	CHEMBL11804::Sodium; (E)-(3R,5S)-9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate::Sodium; 9,9-bis-(4-fluoro-phenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-nona-6,8-dienoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 21							ChEMBL	10.1016/S0960-894X(00)80623-X	10.7270/Q2NG4QJQ				Sit, SY; Parker, RA; Wright, JJ	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014345&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18647991	103926367		CHEMBL11804			C03834	ZINC03782329	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50029746	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1ccc(Cl)cc1Cl	InChI=1S/C13H12Cl2O3/c14-9-3-1-8(12(15)5-9)2-4-11-6-10(16)7-13(17)18-11/h1-5,10-11,16H,6-7H2/b4-2+/t10-,11-/m1/s1	BGASINALMIKBMK-JTNORFRNSA-N	50026112	6-[2-(2,4-Dichloro-phenyl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368928	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 22000							ChEMBL	10.1021/jm00381a014	10.7270/Q2VM4B8T	3973903			Stokker, GE; Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Gilfillan, JL; Huff, JW; Novello, FC; Prugh, JD; Smith, RL	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026112&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			22822816	103935846		CHEMBL2368928				ZINC29409500	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50016481	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C33H33FN2O4/c1-21(2)31-30(33(39)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-27-19-26(37)20-28(38)40-27/h3-16,21,26-27,37H,17-20H2,1-2H3,(H,35,39)/t26-,27-/m1/s1	OUCSEDFVYPBLLF-KAYWLYCHSA-N	50011032	5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide::Atorvastatin lactone::CHEMBL333687::US9006282, Example 3, Compound 2	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011032	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011032&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6483036	103923727		CHEMBL333687		2957		ZINC03920720	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50642306	CC(C)c1c(C(=O)Nc2ccccc2)c(c(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1)-c1ccccc1	InChI=1S/C33H33FN2O4/c1-21(2)31-30(33(39)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-27-19-26(37)20-28(38)40-27/h3-16,21,26-27,37H,17-20H2,1-2H3,(H,35,39)/t26-,27-/m1/s1	OUCSEDFVYPBLLF-KAYWLYCHSA-N	50011032	5-(4-Fluoro-phenyl)-1-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide::Atorvastatin lactone::CHEMBL333687::US9006282, Example 3, Compound 2	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25.0							ChEMBL	10.1021/jm00105a056	10.7270/Q2NV9H6F	1992137			Roth, BD; Blankley, CJ; Chucholowski, AW; Ferguson, E; Hoefle, ML; Ortwine, DF; Newton, RS; Sekerke, CS; Sliskovic, DR; Stratton, CD	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011032	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011032&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6483036	103923727		CHEMBL333687		2957		ZINC03920720	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50033247	CCC(C)(C)OC(=O)C(C1CCCCC1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C27H42O7/c1-6-27(4,5)34-26(32)24(19-10-8-7-9-11-19)22-13-17(2)12-18(3)25(22)33-16-21(29)14-20(28)15-23(30)31/h12-13,19-21,24,28-29H,6-11,14-16H2,1-5H3,(H,30,31)/p-1/t20-,21?,24?/m1/s1	RMQCSWXMHKVTBQ-UZGSZPBKSA-M	50007257	CHEMBL323344::Sodium; 6-{2-[cyclohexyl-(1,1-dimethyl-propoxycarbonyl)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 500							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007257&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928752	103920537		CHEMBL323344			C03834	ZINC26745157	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50643312	OC(COc1c(Cl)cc(Cl)cc1C(c1ccc(F)cc1)c1ccc(F)cc1)C[C@@H](O)CC([O-])=O	InChI=1S/C25H22Cl2F2O5/c26-16-9-21(25(22(27)10-16)34-13-20(31)11-19(30)12-23(32)33)24(14-1-5-17(28)6-2-14)15-3-7-18(29)8-4-15/h1-10,19-20,24,30-31H,11-13H2,(H,32,33)/p-1/t19-,20?/m1/s1	VQWSITRBHPOQTC-FIWHBWSRSA-M	50007289	CHEMBL100721::Sodium; 6-{2-[bis-(4-fluoro-phenyl)-methyl]-4,6-dichloro-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 950							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007289&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928775	103920567		CHEMBL100721			C03834	ZINC26747375	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50643314	CCC(C)(C)C(=O)NC(C1CCCCC1)c1cc(C)cc(C)c1OCC(O)C[C@@H](O)CC([O-])=O	InChI=1S/C27H43NO6/c1-6-27(4,5)26(33)28-24(19-10-8-7-9-11-19)22-13-17(2)12-18(3)25(22)34-16-21(30)14-20(29)15-23(31)32/h12-13,19-21,24,29-30H,6-11,14-16H2,1-5H3,(H,28,33)(H,31,32)/p-1/t20-,21?,24?/m1/s1	XAFSODPXPFYGDP-UZGSZPBKSA-M	50007284	CHEMBL101600::Sodium; 6-{2-[cyclohexyl-(2,2-dimethyl-butyrylamino)-methyl]-4,6-dimethyl-phenoxy}-3,5-dihydroxy-hexanoate	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 320							ChEMBL	10.1021/jm00114a004	10.7270/Q2C829WX	1656041			Jendralla, H; Granzer, E; von Kerekjarto, B; Krause, R; Schacht, U; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Kesseler, K	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50007284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50007284&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928773	103920563		CHEMBL101600			C03834	ZINC26744177	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014080	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19?,20-,21-,23?/m0/s1	PCZOHLXUXFIOCF-QBVZFDLDSA-N	50003235	2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester: 0.1C4H9Cl::BDBM50226269::CHEMBL333443	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 18							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003235&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			9865943	103917215		CHEMBL79583CHEMBL333443				ZINC14984346	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50014096	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19?,20-,21-,23?/m0/s1	RYMZZMVNJRMUDD-RJDSDMDFSA-N	50003240	2,2-Dimethyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::BDBM50024625::CHEMBL3349544	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12							ChEMBL	10.1021/jm00112a027	10.7270/Q2610Z80	1875346			Duggan, ME; Alberts, AW; Bostedor, R; Chao, YS; Germershausen, JI; Gilfillan, JL; Halczenko, W; Hartman, GD; Hunt, V; Imagire, JS	Merck Sharp & Dohme Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003240&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13298846	103917220		CHEMBL3349544CHEMBL309552				ZINC26504557	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032426	Cc1ccc(-c2ccc(cc2)-c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C24H25NO3/c1-17-7-12-23(25(17)14-13-22-15-21(26)16-24(27)28-22)20-10-8-19(9-11-20)18-5-3-2-4-6-18/h2-12,21-22,26H,13-16H2,1H3/t21-,22-/m1/s1	NSUYYCLWHSMXLG-FGZHOGPDSA-N	50014675	6-[2-(2-Biphenyl-4-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL107995	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 23000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014675&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785450	103926570		CHEMBL107995				ZINC26839318	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032427	CC(C)c1ccc(-c2ccccc2Cl)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24ClNO3/c1-13(2)18-7-8-19(16-5-3-4-6-17(16)21)22(18)10-9-15-11-14(23)12-20(24)25-15/h3-8,13-15,23H,9-12H2,1-2H3/t14-,15-/m1/s1	HKCTYZKXOAMQGS-HUUCEWRRSA-N	50014670	6-{2-[2-(2-Chloro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322724	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9100							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014670&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335617	103926565		CHEMBL322724				ZINC26839399	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032429	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032430	Cc1ccc(-c2ccc(F)cc2)n1-c1cccc(c1)[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H20FNO3/c1-14-5-10-20(15-6-8-17(23)9-7-15)24(14)18-4-2-3-16(11-18)21-12-19(25)13-22(26)27-21/h2-11,19,21,25H,12-13H2,1H3/t19-,21+/m1/s1	NRTHZCAQMYJGGO-CTNGQTDRSA-N	50014692	6-{3-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL105511	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 63000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014692&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335495	103926587		CHEMBL105511				ZINC26836203	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032432	Cc1ccc(-c2ccc(F)cc2)n1-c1cccc(c1)[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H20FNO3/c1-14-5-10-20(15-6-8-17(23)9-7-15)24(14)18-4-2-3-16(11-18)21-12-19(25)13-22(26)27-21/h2-11,19,21,25H,12-13H2,1H3/t19-,21+/m1/s1	NRTHZCAQMYJGGO-CTNGQTDRSA-N	50014692	6-{3-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL105511	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 24000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014692&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335495	103926587		CHEMBL105511				ZINC26836203	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032434	COc1cccc(c1)-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-6-7-18(14-4-3-5-16(10-14)23-2)20(13)9-8-17-11-15(21)12-19(22)24-17/h3-7,10,15,17,21H,8-9,11-12H2,1-2H3/t15-,17-/m1/s1	ZUJYBBIDWOTFNW-NVXWUHKLSA-N	50014678	CHEMBL104866::i4-Hydroxy-6-{2-[2-(3-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 11000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014678&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335855	103926573		CHEMBL104866				ZINC26835999	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032435	Cc1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H20FNO3/c1-12-2-7-17(13-3-5-14(19)6-4-13)20(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,21H,8-11H2,1H3/t15-,16-/m1/s1	QNKLRMPQOSICFR-HZPDHXFCSA-N	50014683	CHEMBL104660::i6-{2-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 510							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014683&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18606835	103926578		CHEMBL104660				ZINC26838114	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032436	Cc1ccc(-c2ccc(cc2)-c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C24H25NO3/c1-17-7-12-23(25(17)14-13-22-15-21(26)16-24(27)28-22)20-10-8-19(9-11-20)18-5-3-2-4-6-18/h2-12,21-22,26H,13-16H2,1H3/t21-,22-/m1/s1	NSUYYCLWHSMXLG-FGZHOGPDSA-N	50014675	6-[2-(2-Biphenyl-4-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL107995	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 23000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014675&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785450	103926570		CHEMBL107995				ZINC26839318	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032437	Cc1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H20FNO3/c1-12-2-7-17(13-3-5-14(19)6-4-13)20(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,21H,8-11H2,1H3/t15-,16-/m1/s1	QNKLRMPQOSICFR-HZPDHXFCSA-N	50014683	CHEMBL104660::i6-{2-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2800							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014683&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18606835	103926578		CHEMBL104660				ZINC26838114	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032439	COc1ccc(cc1)-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-3-8-18(14-4-6-16(23-2)7-5-14)20(13)10-9-17-11-15(21)12-19(22)24-17/h3-8,15,17,21H,9-12H2,1-2H3/t15-,17-/m1/s1	ZQIWXGRLHMBHIH-NVXWUHKLSA-N	50014665	4-Hydroxy-6-{2-[2-(4-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL319905	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12589							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014665&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785446	103926560		CHEMBL319905				ZINC26835340	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032440	COc1ccccc1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H27NO4/c1-14(2)18-8-9-19(17-6-4-5-7-20(17)25-3)22(18)11-10-16-12-15(23)13-21(24)26-16/h4-9,14-16,23H,10-13H2,1-3H3/t15-,16-/m1/s1	NYSJCZLVRXRHGX-HZPDHXFCSA-N	50014693	4-Hydroxy-6-{2-[2-isopropyl-5-(2-methoxy-phenyl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104031	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2512							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014693&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335522	103926588		CHEMBL104031				ZINC26835344	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032441	Cc1ccc(-c2cccc(O)c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-5-6-17(13-3-2-4-14(20)9-13)19(12)8-7-16-10-15(21)11-18(22)23-16/h2-6,9,15-16,20-21H,7-8,10-11H2,1H3/t15-,16-/m1/s1	JLJGUVLGBDDOHL-HZPDHXFCSA-N	50014682	CHEMBL105654::i4-Hydroxy-6-{2-[2-(3-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1900							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014682&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335679	103926577		CHEMBL105654				ZINC26833226	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032443	CC(C)c1ccc(-c2ccc(F)cc2F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H23F2NO3/c1-12(2)18-5-6-19(16-4-3-13(21)9-17(16)22)23(18)8-7-15-10-14(24)11-20(25)26-15/h3-6,9,12,14-15,24H,7-8,10-11H2,1-2H3/t14-,15-/m1/s1	FZPCAVZWUCPNEC-HUUCEWRRSA-N	50014680	6-{2-[2-(2,4-Difluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL430472	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1585							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014680&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335523	103926575		CHEMBL430472				ZINC26835346	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032444	CC(C)c1ccc(-c2ccccc2F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-7-8-19(16-5-3-4-6-17(16)21)22(18)10-9-15-11-14(23)12-20(24)25-15/h3-8,13-15,23H,9-12H2,1-2H3/t14-,15-/m1/s1	KSMFJPWAYPAKQZ-HUUCEWRRSA-N	50014684	6-{2-[2-(2-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104595	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1800							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014684&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335602	103926579		CHEMBL104595				ZINC26834201	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032445	CC(C)c1ccc(-c2ccccc2F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-7-8-19(16-5-3-4-6-17(16)21)22(18)10-9-15-11-14(23)12-20(24)25-15/h3-8,13-15,23H,9-12H2,1-2H3/t14-,15-/m1/s1	KSMFJPWAYPAKQZ-HUUCEWRRSA-N	50014684	6-{2-[2-(2-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104595	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3200							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014684&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335602	103926579		CHEMBL104595				ZINC26834201	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032446	CC(C)c1ccc(-c2ccc(F)cc2F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H23F2NO3/c1-12(2)18-5-6-19(16-4-3-13(21)9-17(16)22)23(18)8-7-15-10-14(24)11-20(25)26-15/h3-6,9,12,14-15,24H,7-8,10-11H2,1-2H3/t14-,15-/m1/s1	FZPCAVZWUCPNEC-HUUCEWRRSA-N	50014680	6-{2-[2-(2,4-Difluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL430472	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6310							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014680&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335523	103926575		CHEMBL430472				ZINC26835346	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032450	Cc1ccc(-c2cccc(O)c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-5-6-17(13-3-2-4-14(20)9-13)19(12)8-7-16-10-15(21)11-18(22)23-16/h2-6,9,15-16,20-21H,7-8,10-11H2,1H3/t15-,16-/m1/s1	JLJGUVLGBDDOHL-HZPDHXFCSA-N	50014682	CHEMBL105654::i4-Hydroxy-6-{2-[2-(3-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014682&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335679	103926577		CHEMBL105654				ZINC26833226	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032452	COc1ccccc1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H27NO4/c1-14(2)18-8-9-19(17-6-4-5-7-20(17)25-3)22(18)11-10-16-12-15(23)13-21(24)26-16/h4-9,14-16,23H,10-13H2,1-3H3/t15-,16-/m1/s1	NYSJCZLVRXRHGX-HZPDHXFCSA-N	50014693	4-Hydroxy-6-{2-[2-isopropyl-5-(2-methoxy-phenyl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104031	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6310							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014693&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335522	103926588		CHEMBL104031				ZINC26835344	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032453	COc1ccc(cc1)-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-3-8-18(14-4-6-16(23-2)7-5-14)20(13)10-9-17-11-15(21)12-19(22)24-17/h3-8,15,17,21H,9-12H2,1-2H3/t15-,17-/m1/s1	ZQIWXGRLHMBHIH-NVXWUHKLSA-N	50014665	4-Hydroxy-6-{2-[2-(4-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL319905	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25119							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014665&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785446	103926560		CHEMBL319905				ZINC26835340	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032454	Cc1ccc(-c2ccc(F)cc2)n1-c1ccccc1[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H20FNO3/c1-14-6-11-19(15-7-9-16(23)10-8-15)24(14)20-5-3-2-4-18(20)21-12-17(25)13-22(26)27-21/h2-11,17,21,25H,12-13H2,1H3/t17-,21+/m1/s1	KHSMWSDWTINZRY-UTKZUKDTSA-N	50014685	6-{2-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL317403	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014685&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335521	103926580		CHEMBL317403				ZINC26831212	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032456	Cc1ccc(-c2ccc(F)cc2)n1-c1ccccc1[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H20FNO3/c1-14-6-11-19(15-7-9-16(23)10-8-15)24(14)20-5-3-2-4-18(20)21-12-17(25)13-22(26)27-21/h2-11,17,21,25H,12-13H2,1H3/t17-,21+/m1/s1	KHSMWSDWTINZRY-UTKZUKDTSA-N	50014685	6-{2-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL317403	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014685&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335521	103926580		CHEMBL317403				ZINC26831212	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032459	Cc1ccc(C2CC3CCC2C=C3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H27NO3/c1-13-2-7-19(18-10-14-3-5-15(18)6-4-14)21(13)9-8-17-11-16(22)12-20(23)24-17/h2-3,5,7,14-18,22H,4,6,8-12H2,1H3/t14?,15?,16-,17-,18?/m1/s1	IZGLNLIZJQSJNI-PXUJOYAKSA-N	50014668	6-[2-(2-Bicyclo[2.2.2]oct-5-en-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322656	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1300							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014668&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335641	103926563		CHEMBL322656				ZINC26834181	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032460	Cc1ccc(C2CC3CCC2C=C3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H27NO3/c1-13-2-7-19(18-10-14-3-5-15(18)6-4-14)21(13)9-8-17-11-16(22)12-20(23)24-17/h2-3,5,7,14-18,22H,4,6,8-12H2,1H3/t14?,15?,16-,17-,18?/m1/s1	IZGLNLIZJQSJNI-PXUJOYAKSA-N	50014668	6-[2-(2-Bicyclo[2.2.2]oct-5-en-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322656	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3200							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014668&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335641	103926563		CHEMBL322656				ZINC26834181	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032461	Cc1ccc(C(c2ccccc2)c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H27NO3/c1-18-12-13-23(26(18)15-14-22-16-21(27)17-24(28)29-22)25(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-13,21-22,25,27H,14-17H2,1H3/t21-,22-/m1/s1	ZYOUITAWBXBZCC-FGZHOGPDSA-N	50014689	6-[2-(2-Benzhydryl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104703	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3981							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014689&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785458	103926584		CHEMBL104703				ZINC26837186	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032463	Cc1ccc(-c2cccc(c2)C(F)(F)F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H20F3NO3/c1-12-5-6-17(13-3-2-4-14(9-13)19(20,21)22)23(12)8-7-16-10-15(24)11-18(25)26-16/h2-6,9,15-16,24H,7-8,10-11H2,1H3/t15-,16-/m1/s1	FDQMBHADFAULHR-HZPDHXFCSA-N	50014674	4-Hydroxy-6-{2-[2-methyl-5-(3-trifluoromethyl-phenyl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL321564	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5012							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014674&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335890	103926569		CHEMBL321564				ZINC26835097	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032464	Cc1ccc(-c2cccc(c2)C(F)(F)F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H20F3NO3/c1-12-5-6-17(13-3-2-4-14(9-13)19(20,21)22)23(12)8-7-16-10-15(24)11-18(25)26-16/h2-6,9,15-16,24H,7-8,10-11H2,1H3/t15-,16-/m1/s1	FDQMBHADFAULHR-HZPDHXFCSA-N	50014674	4-Hydroxy-6-{2-[2-methyl-5-(3-trifluoromethyl-phenyl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL321564	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1585							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014674&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335890	103926569		CHEMBL321564				ZINC26835097	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032465	Cc1ccc(C2CC3CCC2C=C3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H27NO3/c1-13-2-7-19(18-10-14-3-5-15(18)6-4-14)21(13)9-8-17-11-16(22)12-20(23)24-17/h2-3,5,7,14-18,22H,4,6,8-12H2,1H3/t14?,15?,16-,17-,18?/m1/s1	IZGLNLIZJQSJNI-PXUJOYAKSA-N	50014668	6-[2-(2-Bicyclo[2.2.2]oct-5-en-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322656	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1259							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014668&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335641	103926563		CHEMBL322656				ZINC26834181	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032466	Cc1ccc(C2CC3CC2C=C3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H25NO3/c1-12-2-5-18(17-9-13-3-4-14(17)8-13)20(12)7-6-16-10-15(21)11-19(22)23-16/h2-5,13-17,21H,6-11H2,1H3/t13?,14?,15-,16-,17?/m1/s1	IHNCWQSEFKFQIZ-VHUWHVEYSA-N	50014688	6-[2-(2-Bicyclo[2.2.1]hept-5-en-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL321914	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6310							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014688&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785456	103926583		CHEMBL321914				ZINC26839261	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032468	Cc1ccc(-c2cccc(O)c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-5-6-17(13-3-2-4-14(20)9-13)19(12)8-7-16-10-15(21)11-18(22)23-16/h2-6,9,15-16,20-21H,7-8,10-11H2,1H3/t15-,16-/m1/s1	JLJGUVLGBDDOHL-HZPDHXFCSA-N	50014682	CHEMBL105654::i4-Hydroxy-6-{2-[2-(3-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1995							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014682&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335679	103926577		CHEMBL105654				ZINC26833226	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032469	O[C@@H]1C[C@@H](CCn2c(ccc2-c2ccc(F)cc2)C2CCCCC2)OC(=O)C1	InChI=1S/C23H28FNO3/c24-18-8-6-17(7-9-18)22-11-10-21(16-4-2-1-3-5-16)25(22)13-12-20-14-19(26)15-23(27)28-20/h6-11,16,19-20,26H,1-5,12-15H2/t19-,20-/m1/s1	CQLCSKXQNGSOLY-WOJBJXKFSA-N	50014681	6-{2-[2-Cyclohexyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322367	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014681&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335592	103926576		CHEMBL322367				ZINC26836770	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032471	O[C@@H]1C[C@@H](CCn2c(ccc2C(F)(F)F)-c2ccc(F)cc2)OC(=O)C1	InChI=1S/C18H17F4NO3/c19-12-3-1-11(2-4-12)15-5-6-16(18(20,21)22)23(15)8-7-14-9-13(24)10-17(25)26-14/h1-6,13-14,24H,7-10H2/t13-,14-/m1/s1	WWKQYHAFGOBLDP-ZIAGYGMSSA-N	50014667	6-{2-[2-(4-Fluoro-phenyl)-5-trifluoromethyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322366	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 631							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014667&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335591	103926562		CHEMBL322366				ZINC26836766	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032472	Cc1ccc(C2CC3CCC2CC3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H29NO3/c1-13-2-7-19(18-10-14-3-5-15(18)6-4-14)21(13)9-8-17-11-16(22)12-20(23)24-17/h2,7,14-18,22H,3-6,8-12H2,1H3/t14?,15?,16-,17-,18?/m1/s1	JLQQCFATUIPBTG-PXUJOYAKSA-N	50014698	6-[2-(2-Bicyclo[2.2.2]oct-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL265305	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2300							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014698&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335733	103926593		CHEMBL265305				ZINC26834164	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032475	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032477	CC(C)c1ccc(-c2cccc(F)c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-6-7-19(14-4-3-5-15(21)10-14)22(18)9-8-17-11-16(23)12-20(24)25-17/h3-7,10,13,16-17,23H,8-9,11-12H2,1-2H3/t16-,17-/m1/s1	AHVDPZLQANCRDN-IAGOWNOFSA-N	50014671	6-{2-[2-(3-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104295	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2512							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014671&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335590	103926566		CHEMBL104295				ZINC26836762	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032480	Cc1ccc(-c2ccc(F)cc2)n1-c1ccccc1[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H20FNO3/c1-14-6-11-19(15-7-9-16(23)10-8-15)24(14)20-5-3-2-4-18(20)21-12-17(25)13-22(26)27-21/h2-11,17,21,25H,12-13H2,1H3/t17-,21+/m1/s1	KHSMWSDWTINZRY-UTKZUKDTSA-N	50014685	6-{2-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL317403	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014685&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335521	103926580		CHEMBL317403				ZINC26831212	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032481	COc1ccc(cc1)-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-3-8-18(14-4-6-16(23-2)7-5-14)20(13)10-9-17-11-15(21)12-19(22)24-17/h3-8,15,17,21H,9-12H2,1-2H3/t15-,17-/m1/s1	ZQIWXGRLHMBHIH-NVXWUHKLSA-N	50014665	4-Hydroxy-6-{2-[2-(4-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL319905	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 28000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014665&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785446	103926560		CHEMBL319905				ZINC26835340	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032483	CCC(CC)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H28FNO3/c1-3-15(4-2)20-9-10-21(16-5-7-17(23)8-6-16)24(20)12-11-19-13-18(25)14-22(26)27-19/h5-10,15,18-19,25H,3-4,11-14H2,1-2H3/t18-,19-/m1/s1	OOANXJFGKWCWIB-RTBURBONSA-N	50014697	6-{2-[2-(1-Ethyl-propyl)-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL321930	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 31623							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014697&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335567	103926592		CHEMBL321930				ZINC26832449	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032484	Cc1ccc(-c2ccc3ccccc3c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H23NO3/c1-15-6-9-21(18-8-7-16-4-2-3-5-17(16)12-18)23(15)11-10-20-13-19(24)14-22(25)26-20/h2-9,12,19-20,24H,10-11,13-14H2,1H3/t19-,20-/m1/s1	YAGSCRJOPNSMPV-WOJBJXKFSA-N	50014696	4-Hydroxy-6-[2-(2-methyl-5-naphthalen-2-yl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL317885	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 16000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014696&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785454	103926591		CHEMBL317885				ZINC26834167	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082307	COc1ccccc1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H27NO4/c1-14(2)18-8-9-19(17-6-4-5-7-20(17)25-3)22(18)11-10-16-12-15(23)13-21(24)26-16/h4-9,14-16,23H,10-13H2,1-3H3/t15-,16-/m1/s1	NYSJCZLVRXRHGX-HZPDHXFCSA-N	50014693	4-Hydroxy-6-{2-[2-isopropyl-5-(2-methoxy-phenyl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104031	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5600							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014693&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335522	103926588		CHEMBL104031				ZINC26835344	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082308	O[C@@H]1C[C@@H](CCn2c(ccc2-c2ccc(F)cc2)C2CC2)OC(=O)C1	InChI=1S/C20H22FNO3/c21-15-5-3-14(4-6-15)19-8-7-18(13-1-2-13)22(19)10-9-17-11-16(23)12-20(24)25-17/h3-8,13,16-17,23H,1-2,9-12H2/t16-,17-/m1/s1	YXISEZLIKDLBHD-IAGOWNOFSA-N	50014695	6-{2-[2-Cyclopropyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL106062	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2512							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014695&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335566	103926590		CHEMBL106062				ZINC26832445	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082309	CC(C)c1ccc(-c2ccccc2F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-7-8-19(16-5-3-4-6-17(16)21)22(18)10-9-15-11-14(23)12-20(24)25-15/h3-8,13-15,23H,9-12H2,1-2H3/t14-,15-/m1/s1	KSMFJPWAYPAKQZ-HUUCEWRRSA-N	50014684	6-{2-[2-(2-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104595	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3162							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014684&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335602	103926579		CHEMBL104595				ZINC26834201	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082310	CC(C)c1ccc(-c2ccc(F)cc2F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H23F2NO3/c1-12(2)18-5-6-19(16-4-3-13(21)9-17(16)22)23(18)8-7-15-10-14(24)11-20(25)26-15/h3-6,9,12,14-15,24H,7-8,10-11H2,1-2H3/t14-,15-/m1/s1	FZPCAVZWUCPNEC-HUUCEWRRSA-N	50014680	6-{2-[2-(2,4-Difluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL430472	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2600							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014680&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335523	103926575		CHEMBL430472				ZINC26835346	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082311	COc1ccccc1-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-7-8-17(16-5-3-4-6-18(16)23-2)20(13)10-9-15-11-14(21)12-19(22)24-15/h3-8,14-15,21H,9-12H2,1-2H3/t14-,15-/m1/s1	WQWAGILDBLSBQH-HUUCEWRRSA-N	50014694	4-Hydroxy-6-{2-[2-(2-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL317854	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25119							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014694&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785444	103926589		CHEMBL317854				ZINC26835406	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082312	COc1ccc2ccccc2c1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H29NO4/c1-16(2)21-9-10-22(26(21)13-12-19-14-18(27)15-24(28)30-19)25-20-7-5-4-6-17(20)8-11-23(25)29-3/h4-11,16,18-19,27H,12-15H2,1-3H3/t18-,19-/m1/s1	WFMHEDHHCWBSIB-RTBURBONSA-N	50014699	4-Hydroxy-6-{2-[2-isopropyl-5-(2-methoxy-naphthalen-1-yl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104639	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 9600							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014699&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335605	103926594		CHEMBL104639				ZINC26834871	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082313	Cc1ccc(-c2ccc(O)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-2-7-17(13-3-5-14(20)6-4-13)19(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,20-21H,8-11H2,1H3/t15-,16-/m1/s1	NWLCBPATGSGBMW-HZPDHXFCSA-N	50014703	4-Hydroxy-6-{2-[2-(4-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL106167	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2600							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014703&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335903	103926598		CHEMBL106167				ZINC26831868	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082314	Cc1ccc(-c2cccc3ccccc23)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H23NO3/c1-15-9-10-21(20-8-4-6-16-5-2-3-7-19(16)20)23(15)12-11-18-13-17(24)14-22(25)26-18/h2-10,17-18,24H,11-14H2,1H3/t17-,18-/m1/s1	MVCRJKMSDFMOAD-QZTJIDSGSA-N	50014690	4-Hydroxy-6-[2-(2-methyl-5-naphthalen-1-yl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL320352	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1800							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014690&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785452	103926585		CHEMBL320352				ZINC26839364	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082315	CC(C)c1ccc(-c2ccc(F)cc2)n1CC(C)[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H26FNO3/c1-13(2)18-8-9-19(15-4-6-16(22)7-5-15)23(18)12-14(3)20-10-17(24)11-21(25)26-20/h4-9,13-14,17,20,24H,10-12H2,1-3H3/t14?,17-,20+/m1/s1	OMUIQGPGHFNSLA-SBCCGAISSA-N	50014691	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-1-methyl-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL318596	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 40000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014691&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335922	103926586		CHEMBL318596				ZINC26835130	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082316	Cc1ccc(C2CCCCC2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H27NO3/c1-13-7-8-17(14-5-3-2-4-6-14)19(13)10-9-16-11-15(20)12-18(21)22-16/h7-8,14-16,20H,2-6,9-12H2,1H3/t15-,16-/m1/s1	PLAOFIRLJLTRNR-HZPDHXFCSA-N	50014701	6-[2-(2-Cyclohexyl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL107753	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 631							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014701&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785448	103926596		CHEMBL107753				ZINC26839065	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082319	CC(C)Oc1ccccc1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C23H31NO4/c1-15(2)20-9-10-21(19-7-5-6-8-22(19)27-16(3)4)24(20)12-11-18-13-17(25)14-23(26)28-18/h5-10,15-18,25H,11-14H2,1-4H3/t17-,18-/m1/s1	STNUXLZOZDUOQU-QZTJIDSGSA-N	50014700	4-Hydroxy-6-{2-[2-(2-isopropoxy-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104184	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3200							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014700&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335684	103926595		CHEMBL104184				ZINC26834472	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082320	Cc1ccc(C2CCCCC2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H27NO3/c1-13-7-8-17(14-5-3-2-4-6-14)19(13)10-9-16-11-15(20)12-18(21)22-16/h7-8,14-16,20H,2-6,9-12H2,1H3/t15-,16-/m1/s1	PLAOFIRLJLTRNR-HZPDHXFCSA-N	50014701	6-[2-(2-Cyclohexyl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL107753	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2512							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014701&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785448	103926596		CHEMBL107753				ZINC26839065	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082321	CC(C)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-7-8-19(14-3-5-15(21)6-4-14)22(18)10-9-17-11-16(23)12-20(24)25-17/h3-8,13,16-17,23H,9-12H2,1-2H3/t16-,17-/m1/s1	ZYSGPNCFTPUHGN-IAGOWNOFSA-N	50011034	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104044	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 230							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011034	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011034&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785438	103923729		CHEMBL104044				ZINC13861016	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082322	CC(C)(C)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H26FNO3/c1-21(2,3)19-9-8-18(14-4-6-15(22)7-5-14)23(19)11-10-17-12-16(24)13-20(25)26-17/h4-9,16-17,24H,10-13H2,1-3H3/t16-,17-/m1/s1	PMSBINLIZBHCDF-IAGOWNOFSA-N	50014686	6-{2-[2-tert-Butyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL319870	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1585							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014686&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785442	103926581		CHEMBL319870				ZINC26833587	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082323	CC(C)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-7-8-19(14-3-5-15(21)6-4-14)22(18)10-9-17-11-16(23)12-20(24)25-17/h3-8,13,16-17,23H,9-12H2,1-2H3/t16-,17-/m1/s1	ZYSGPNCFTPUHGN-IAGOWNOFSA-N	50011034	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104044	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 400							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011034	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011034&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785438	103923729		CHEMBL104044				ZINC13861016	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082324	Cc1ccc(-c2ccccc2O)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-6-7-16(15-4-2-3-5-17(15)21)19(12)9-8-14-10-13(20)11-18(22)23-14/h2-7,13-14,20-21H,8-11H2,1H3/t13-,14-/m1/s1	HRJNORMWLOECJJ-ZIAGYGMSSA-N	50014673	4-Hydroxy-6-{2-[2-(2-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104405	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 31623							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014673&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335883	103926568		CHEMBL104405				ZINC26835403	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082325	Cc1ccc(-c2ccccc2O)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-6-7-16(15-4-2-3-5-17(15)21)19(12)9-8-14-10-13(20)11-18(22)23-14/h2-7,13-14,20-21H,8-11H2,1H3/t13-,14-/m1/s1	HRJNORMWLOECJJ-ZIAGYGMSSA-N	50014673	4-Hydroxy-6-{2-[2-(2-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104405	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2512							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014673&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335883	103926568		CHEMBL104405				ZINC26835403	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082326	CC(C)(C)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H26FNO3/c1-21(2,3)19-9-8-18(14-4-6-15(22)7-5-14)23(19)11-10-17-12-16(24)13-20(25)26-17/h4-9,16-17,24H,10-13H2,1-3H3/t16-,17-/m1/s1	PMSBINLIZBHCDF-IAGOWNOFSA-N	50014686	6-{2-[2-tert-Butyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL319870	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1995							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014686&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785442	103926581		CHEMBL319870				ZINC26833587	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082337	COc1cccc(OC)c1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H29NO5/c1-14(2)17-8-9-18(22-19(26-3)6-5-7-20(22)27-4)23(17)11-10-16-12-15(24)13-21(25)28-16/h5-9,14-16,24H,10-13H2,1-4H3/t15-,16-/m1/s1	VGXGUJPBOIYJRO-HZPDHXFCSA-N	50014672	6-{2-[2-(2,6-Dimethoxy-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL323256	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 87000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014672&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335570	103926567		CHEMBL323256				ZINC26849023	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50082338	COc1cccc(OC)c1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H29NO5/c1-14(2)17-8-9-18(22-19(26-3)6-5-7-20(22)27-4)23(17)11-10-16-12-15(24)13-21(25)28-16/h5-9,14-16,24H,10-13H2,1-4H3/t15-,16-/m1/s1	VGXGUJPBOIYJRO-HZPDHXFCSA-N	50014672	6-{2-[2-(2,6-Dimethoxy-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL323256	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 19000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014672&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335570	103926567		CHEMBL323256				ZINC26849023	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50088143	CC(C)c1ccc(-c2cccc(F)c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-6-7-19(14-4-3-5-15(21)10-14)22(18)9-8-17-11-16(23)12-20(24)25-17/h3-7,10,13,16-17,23H,8-9,11-12H2,1-2H3/t16-,17-/m1/s1	AHVDPZLQANCRDN-IAGOWNOFSA-N	50014671	6-{2-[2-(3-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104295	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1259							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014671&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335590	103926566		CHEMBL104295				ZINC26836762	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50088144	COc1ccc2ccccc2c1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H29NO4/c1-16(2)21-9-10-22(26(21)13-12-19-14-18(27)15-24(28)30-19)25-20-7-5-4-6-17(20)8-11-23(25)29-3/h4-11,16,18-19,27H,12-15H2,1-3H3/t18-,19-/m1/s1	WFMHEDHHCWBSIB-RTBURBONSA-N	50014699	4-Hydroxy-6-{2-[2-isopropyl-5-(2-methoxy-naphthalen-1-yl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104639	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014699&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335605	103926594		CHEMBL104639				ZINC26834871	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50088145	O[C@@H]1C[C@@H](CCn2c(ccc2-c2ccc(F)cc2)C2CC2)OC(=O)C1	InChI=1S/C20H22FNO3/c21-15-5-3-14(4-6-15)19-8-7-18(13-1-2-13)22(19)10-9-17-11-16(23)12-20(24)25-17/h3-8,13,16-17,23H,1-2,9-12H2/t16-,17-/m1/s1	YXISEZLIKDLBHD-IAGOWNOFSA-N	50014695	6-{2-[2-Cyclopropyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL106062	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1995							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014695&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335566	103926590		CHEMBL106062				ZINC26832445	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50088146	CCC(CC)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H28FNO3/c1-3-15(4-2)20-9-10-21(16-5-7-17(23)8-6-16)24(20)12-11-19-13-18(25)14-22(26)27-19/h5-10,15,18-19,25H,3-4,11-14H2,1-2H3/t18-,19-/m1/s1	OOANXJFGKWCWIB-RTBURBONSA-N	50014697	6-{2-[2-(1-Ethyl-propyl)-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL321930	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 19953							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014697&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335567	103926592		CHEMBL321930				ZINC26832449	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50088147	Cc1ccc(C(c2ccccc2)c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H27NO3/c1-18-12-13-23(26(18)15-14-22-16-21(27)17-24(28)29-22)25(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-13,21-22,25,27H,14-17H2,1H3/t21-,22-/m1/s1	ZYOUITAWBXBZCC-FGZHOGPDSA-N	50014689	6-[2-(2-Benzhydryl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104703	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12589							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014689&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785458	103926584		CHEMBL104703				ZINC26837186	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50088148	O[C@@H]1C[C@@H](CCn2c(ccc2-c2ccc(F)cc2)C2CCCCC2)OC(=O)C1	InChI=1S/C23H28FNO3/c24-18-8-6-17(7-9-18)22-11-10-21(16-4-2-1-3-5-16)25(22)13-12-20-14-19(26)15-23(27)28-20/h6-11,16,19-20,26H,1-5,12-15H2/t19-,20-/m1/s1	CQLCSKXQNGSOLY-WOJBJXKFSA-N	50014681	6-{2-[2-Cyclohexyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322367	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014681&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335592	103926576		CHEMBL322367				ZINC26836770	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50088149	Cc1ccc(C2CC3CCC2CC3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H29NO3/c1-13-2-7-19(18-10-14-3-5-15(18)6-4-14)21(13)9-8-17-11-16(22)12-20(23)24-17/h2,7,14-18,22H,3-6,8-12H2,1H3/t14?,15?,16-,17-,18?/m1/s1	JLQQCFATUIPBTG-PXUJOYAKSA-N	50014698	6-[2-(2-Bicyclo[2.2.2]oct-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL265305	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2300							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014698&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335733	103926593		CHEMBL265305				ZINC26834164	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50352201	O[C@@H]1C[C@@H](CCn2c(ccc2C(F)(F)F)-c2ccc(F)cc2)OC(=O)C1	InChI=1S/C18H17F4NO3/c19-12-3-1-11(2-4-12)15-5-6-16(18(20,21)22)23(15)8-7-14-9-13(24)10-17(25)26-14/h1-6,13-14,24H,7-10H2/t13-,14-/m1/s1	WWKQYHAFGOBLDP-ZIAGYGMSSA-N	50014667	6-{2-[2-(4-Fluoro-phenyl)-5-trifluoromethyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322366	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 251							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014667&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335591	103926562		CHEMBL322366				ZINC26836766	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50387698	Cc1ccc(-c2ccc3ccccc3c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H23NO3/c1-15-6-9-21(18-8-7-16-4-2-3-5-17(16)12-18)23(15)11-10-20-13-19(24)14-22(25)26-20/h2-9,12,19-20,24H,10-11,13-14H2,1H3/t19-,20-/m1/s1	YAGSCRJOPNSMPV-WOJBJXKFSA-N	50014696	4-Hydroxy-6-[2-(2-methyl-5-naphthalen-2-yl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL317885	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3600							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014696&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785454	103926591		CHEMBL317885				ZINC26834167	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50501213	Cc1ccc(C2CC3CC2C=C3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H25NO3/c1-12-2-5-18(17-9-13-3-4-14(17)8-13)20(12)7-6-16-10-15(21)11-19(22)23-16/h2-5,13-17,21H,6-11H2,1H3/t13?,14?,15-,16-,17?/m1/s1	IHNCWQSEFKFQIZ-VHUWHVEYSA-N	50014688	6-[2-(2-Bicyclo[2.2.1]hept-5-en-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL321914	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1585							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014688&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785456	103926583		CHEMBL321914				ZINC26839261	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627030	COc1ccccc1-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-7-8-17(16-5-3-4-6-18(16)23-2)20(13)10-9-15-11-14(21)12-19(22)24-15/h3-8,14-15,21H,9-12H2,1-2H3/t14-,15-/m1/s1	WQWAGILDBLSBQH-HUUCEWRRSA-N	50014694	4-Hydroxy-6-{2-[2-(2-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL317854	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1995							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014694&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785444	103926589		CHEMBL317854				ZINC26835406	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627031	CC(C)c1ccc(-c2cc(C)ccc2C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H29NO3/c1-14(2)20-7-8-21(19-11-15(3)5-6-16(19)4)23(20)10-9-18-12-17(24)13-22(25)26-18/h5-8,11,14,17-18,24H,9-10,12-13H2,1-4H3/t17-,18-/m1/s1	WEXBLGVLOVZWCC-QZTJIDSGSA-N	50014687	6-{2-[2-(2,5-Dimethyl-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL280437	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 12589							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014687&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335612	103926582		CHEMBL280437				ZINC26830938	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627032	CCC(CC)c1ccc(C(CC)CC)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H35NO3/c1-5-15(6-2)19-9-10-20(16(7-3)8-4)22(19)12-11-18-13-17(23)14-21(24)25-18/h9-10,15-18,23H,5-8,11-14H2,1-4H3/t17-,18-/m1/s1	OKNAQZCHMPMIGW-QZTJIDSGSA-N	50014666	6-{2-[2,5-Bis-(1-ethyl-propyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104221	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014666&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335627	103926561		CHEMBL104221				ZINC26837797	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627033	CC(C)c1ccc(-c2cc(C)ccc2C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H29NO3/c1-14(2)20-7-8-21(19-11-15(3)5-6-16(19)4)23(20)10-9-18-12-17(24)13-22(25)26-18/h5-8,11,14,17-18,24H,9-10,12-13H2,1-4H3/t17-,18-/m1/s1	WEXBLGVLOVZWCC-QZTJIDSGSA-N	50014687	6-{2-[2-(2,5-Dimethyl-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL280437	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15849							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014687&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335612	103926582		CHEMBL280437				ZINC26830938	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627034	CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1	AJLFOPYRIVGYMJ-INTXDZFKSA-N	50011036	(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate::(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin)::CHEMBL54440::MEVASTATIN::cid_64715::compactin	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011036&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	2UO	4OQR	64715	103923731		CHEMBL54440		3031	C13963	ZINC03833876	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627035	Cc1ccc(-c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO3/c1-13-7-8-17(14-5-3-2-4-6-14)19(13)10-9-16-11-15(20)12-18(21)22-16/h2-8,15-16,20H,9-12H2,1H3/t15-,16-/m1/s1	GRYRYCIEQRBDRS-HZPDHXFCSA-N	50014676	4-Hydroxy-6-[2-(2-methyl-5-phenyl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL106720	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014676&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785440	103926571		CHEMBL106720				ZINC26836779	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627036	Cc1ccc(-c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO3/c1-13-7-8-17(14-5-3-2-4-6-14)19(13)10-9-16-11-15(20)12-18(21)22-16/h2-8,15-16,20H,9-12H2,1H3/t15-,16-/m1/s1	GRYRYCIEQRBDRS-HZPDHXFCSA-N	50014676	4-Hydroxy-6-[2-(2-methyl-5-phenyl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL106720	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1400							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014676&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785440	103926571		CHEMBL106720				ZINC26836779	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627037	CC(C)c1ccc(-c2ccc(F)cc2)n1CC(C)[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H26FNO3/c1-13(2)18-8-9-19(15-4-6-16(22)7-5-15)23(18)12-14(3)20-10-17(24)11-21(25)26-20/h4-9,13-14,17,20,24H,10-12H2,1-3H3/t14?,17-,20+/m1/s1	OMUIQGPGHFNSLA-SBCCGAISSA-N	50014691	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-1-methyl-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL318596	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 39811							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014691&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335922	103926586		CHEMBL318596				ZINC26835130	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627038	CC(C)c1ccc(-c2ccc(F)cc2)n1CC(C)[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H26FNO3/c1-13(2)18-8-9-19(15-4-6-16(22)7-5-15)23(18)12-14(3)20-10-17(24)11-21(25)26-20/h4-9,13-14,17,20,24H,10-12H2,1-3H3/t14?,17-,20+/m1/s1	OMUIQGPGHFNSLA-SBCCGAISSA-N	50014691	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-1-methyl-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL318596	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5012							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014691&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335922	103926586		CHEMBL318596				ZINC26835130	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627039	Cc1ccc(-c2ccc(O)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-2-7-17(13-3-5-14(20)6-4-13)19(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,20-21H,8-11H2,1H3/t15-,16-/m1/s1	NWLCBPATGSGBMW-HZPDHXFCSA-N	50014703	4-Hydroxy-6-{2-[2-(4-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL106167	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2512							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014703&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335903	103926598		CHEMBL106167				ZINC26831868	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627040	Cc1ccc(-c2cccc3ccccc23)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H23NO3/c1-15-9-10-21(20-8-4-6-16-5-2-3-7-19(16)20)23(15)12-11-18-13-17(24)14-22(25)26-18/h2-10,17-18,24H,11-14H2,1H3/t17-,18-/m1/s1	MVCRJKMSDFMOAD-QZTJIDSGSA-N	50014690	4-Hydroxy-6-[2-(2-methyl-5-naphthalen-1-yl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL320352	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1585							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014690&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785452	103926585		CHEMBL320352				ZINC26839364	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627041	Cc1ccc(-c2cccc3ccccc23)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H23NO3/c1-15-9-10-21(20-8-4-6-16-5-2-3-7-19(16)20)23(15)12-11-18-13-17(24)14-22(25)26-18/h2-10,17-18,24H,11-14H2,1H3/t17-,18-/m1/s1	MVCRJKMSDFMOAD-QZTJIDSGSA-N	50014690	4-Hydroxy-6-[2-(2-methyl-5-naphthalen-1-yl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL320352	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014690&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785452	103926585		CHEMBL320352				ZINC26839364	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627058	Cc1ccc(-c2ccc(O)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-2-7-17(13-3-5-14(20)6-4-13)19(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,20-21H,8-11H2,1H3/t15-,16-/m1/s1	NWLCBPATGSGBMW-HZPDHXFCSA-N	50014703	4-Hydroxy-6-{2-[2-(4-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL106167	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 6310							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014703&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335903	103926598		CHEMBL106167				ZINC26831868	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627074	Cc1ccc(-c2ccc(Cl)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H20ClNO3/c1-12-2-7-17(13-3-5-14(19)6-4-13)20(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,21H,8-11H2,1H3/t15-,16-/m1/s1	GVJDVHXMPCFWFM-HZPDHXFCSA-N	50014677	6-{2-[2-(4-Chloro-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL323019	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014677&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335689	103926572		CHEMBL323019				ZINC26837126	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627104	Cc1ccc(-c2ccc(Cl)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H20ClNO3/c1-12-2-7-17(13-3-5-14(19)6-4-13)20(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,21H,8-11H2,1H3/t15-,16-/m1/s1	GVJDVHXMPCFWFM-HZPDHXFCSA-N	50014677	6-{2-[2-(4-Chloro-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL323019	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3200							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014677&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335689	103926572		CHEMBL323019				ZINC26837126	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627125	Cc1ccc(-c2ccc(Cl)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H20ClNO3/c1-12-2-7-17(13-3-5-14(19)6-4-13)20(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,21H,8-11H2,1H3/t15-,16-/m1/s1	GVJDVHXMPCFWFM-HZPDHXFCSA-N	50014677	6-{2-[2-(4-Chloro-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL323019	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014677&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335689	103926572		CHEMBL323019				ZINC26837126	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627146	O[C@@H]1C[C@@H](CCn2c(ccc2-c2ccc(F)cc2)C2CCC2)OC(=O)C1	InChI=1S/C21H24FNO3/c22-16-6-4-15(5-7-16)20-9-8-19(14-2-1-3-14)23(20)11-10-18-12-17(24)13-21(25)26-18/h4-9,14,17-18,24H,1-3,10-13H2/t17-,18-/m1/s1	FPDGWLPNKJTZQU-QZTJIDSGSA-N	50014704	6-{2-[2-Cyclobutyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL107746	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 15849							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014704&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335584	103926599		CHEMBL107746				ZINC26837520	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627147	Cc1ccc(-c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO3/c1-13-7-8-17(14-5-3-2-4-6-14)19(13)10-9-16-11-15(20)12-18(21)22-16/h2-8,15-16,20H,9-12H2,1H3/t15-,16-/m1/s1	GRYRYCIEQRBDRS-HZPDHXFCSA-N	50014676	4-Hydroxy-6-[2-(2-methyl-5-phenyl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL106720	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1259							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014676&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785440	103926571		CHEMBL106720				ZINC26836779	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627148	CC(C)(C)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C21H26FNO3/c1-21(2,3)19-9-8-18(14-4-6-15(22)7-5-14)23(19)11-10-17-12-16(24)13-20(25)26-17/h4-9,16-17,24H,10-13H2,1-3H3/t16-,17-/m1/s1	PMSBINLIZBHCDF-IAGOWNOFSA-N	50014686	6-{2-[2-tert-Butyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL319870	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1600							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014686&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785442	103926581		CHEMBL319870				ZINC26833587	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627149	COc1ccccc1-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-7-8-17(16-5-3-4-6-18(16)23-2)20(13)10-9-15-11-14(21)12-19(22)24-15/h3-8,14-15,21H,9-12H2,1-2H3/t14-,15-/m1/s1	WQWAGILDBLSBQH-HUUCEWRRSA-N	50014694	4-Hydroxy-6-{2-[2-(2-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL317854	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2100							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014694&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785444	103926589		CHEMBL317854				ZINC26835406	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627150	COc1cccc(OC)c1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H29NO5/c1-14(2)17-8-9-18(22-19(26-3)6-5-7-20(22)27-4)23(17)11-10-16-12-15(24)13-21(25)28-16/h5-9,14-16,24H,10-13H2,1-4H3/t15-,16-/m1/s1	VGXGUJPBOIYJRO-HZPDHXFCSA-N	50014672	6-{2-[2-(2,6-Dimethoxy-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL323256	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 79433							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014672&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335570	103926567		CHEMBL323256				ZINC26849023	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627151	Cc1ccc(C2CCCCC2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H27NO3/c1-13-7-8-17(14-5-3-2-4-6-14)19(13)10-9-16-11-15(20)12-18(21)22-16/h7-8,14-16,20H,2-6,9-12H2,1H3/t15-,16-/m1/s1	PLAOFIRLJLTRNR-HZPDHXFCSA-N	50014701	6-[2-(2-Cyclohexyl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL107753	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 690							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014701&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785448	103926596		CHEMBL107753				ZINC26839065	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627152	Cc1ccc(-c2ccccc2O)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H21NO4/c1-12-6-7-16(15-4-2-3-5-17(15)21)19(12)9-8-14-10-13(20)11-18(22)23-14/h2-7,13-14,20-21H,8-11H2,1H3/t13-,14-/m1/s1	HRJNORMWLOECJJ-ZIAGYGMSSA-N	50014673	4-Hydroxy-6-{2-[2-(2-hydroxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104405	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2500							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014673&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335883	103926568		CHEMBL104405				ZINC26835403	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627153	CC(C)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-7-8-19(14-3-5-15(21)6-4-14)22(18)10-9-17-11-16(23)12-20(24)25-17/h3-8,13,16-17,23H,9-12H2,1-2H3/t16-,17-/m1/s1	ZYSGPNCFTPUHGN-IAGOWNOFSA-N	50011034	6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104044	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 251							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50011034	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50011034&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785438	103923729		CHEMBL104044				ZINC13861016	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627154	Cc1ccc(-c2ccc(F)cc2)n1CCC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H22FNO3/c1-13-4-9-18(14-5-7-15(20)8-6-14)21(13)10-2-3-17-11-16(22)12-19(23)24-17/h4-9,16-17,22H,2-3,10-12H2,1H3/t16-,17-/m1/s1	SNRLXLKLVVFAQQ-IAGOWNOFSA-N	50014702	6-{3-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-propyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104038	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 50119							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014702&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335692	103926597		CHEMBL104038				ZINC26835884	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627155	CC(C)c1ccc(-c2cc(C)ccc2C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H29NO3/c1-14(2)20-7-8-21(19-11-15(3)5-6-16(19)4)23(20)10-9-18-12-17(24)13-22(25)26-18/h5-8,11,14,17-18,24H,9-10,12-13H2,1-4H3/t17-,18-/m1/s1	WEXBLGVLOVZWCC-QZTJIDSGSA-N	50014687	6-{2-[2-(2,5-Dimethyl-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL280437	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 16000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014687&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335612	103926582		CHEMBL280437				ZINC26830938	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50612149	O[C@@H]1C[C@@H](CCc2c(Cl)cc(Cl)cc2OCc2ccccc2)OC(=O)C1	InChI=1S/C20H20Cl2O4/c21-14-8-18(22)17(7-6-16-10-15(23)11-20(24)26-16)19(9-14)25-12-13-4-2-1-3-5-13/h1-5,8-9,15-16,23H,6-7,10-12H2/t15-,16-/m1/s1	GMFRNTNFNHPQRE-HZPDHXFCSA-N	50405308	CHEMBL2115421	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 200							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405308&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13186026	163354332		CHEMBL2115421				ZINC29410867	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50612150	O[C@@H]1C[C@@H](CCc2c(Cl)cc(Cl)cc2OCc2ccccc2)OC(=O)C1	InChI=1S/C20H20Cl2O4/c21-14-8-18(22)17(7-6-16-10-15(23)11-20(24)26-16)19(9-14)25-12-13-4-2-1-3-5-13/h1-5,8-9,15-16,23H,6-7,10-12H2/t15-,16-/m1/s1	GMFRNTNFNHPQRE-HZPDHXFCSA-N	50405308	CHEMBL2115421	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5200							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405308&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13186026	163354332		CHEMBL2115421				ZINC29410867	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50612151	O[C@@H]1C[C@@H](CCc2c(Cl)cc(Cl)cc2OCc2ccc(F)cc2)OC(=O)C1	InChI=1S/C20H19Cl2FO4/c21-13-7-18(22)17(6-5-16-9-15(24)10-20(25)27-16)19(8-13)26-11-12-1-3-14(23)4-2-12/h1-4,7-8,15-16,24H,5-6,9-11H2/t15-,16-/m1/s1	YOFPIUPACOQONI-HZPDHXFCSA-N	50405306	CHEMBL2114971	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 76.0							ChEMBL	10.1021/jm00152a001	10.7270/Q2WM1CFN	3950901			Hoffman, WF; Alberts, AW; Cragoe, EJ; Deana, AA; Evans, BE; Gilfillan, JL; Gould, NP; Huff, JW; Novello, FC; Prugh, JD	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50405306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50405306&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13186038	163354330		CHEMBL2114971				ZINC29409173	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030070	Cc1cc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(F)c(C)c1	InChI=1S/C22H23FO3/c1-13-8-14(2)19(6-5-18-11-17(24)12-22(25)26-18)20(9-13)16-4-7-21(23)15(3)10-16/h4-10,17-18,24H,11-12H2,1-3H3/b6-5+/t17-,18-/m1/s1	BNIBDNOALUGLCI-PJHKVULZSA-N	50014669	6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL440891	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.6							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014669&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6439709	103926564		CHEMBL440891				ZINC06069734	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50612152	Cc1cc(C)c(\C=C\[C@@H]2C[C@@H](O)CC(=O)O2)c(c1)-c1ccc(F)c(C)c1	InChI=1S/C22H23FO3/c1-13-8-14(2)19(6-5-18-11-17(24)12-22(25)26-18)20(9-13)16-4-7-21(23)15(3)10-16/h4-10,17-18,24H,11-12H2,1-3H3/b6-5+/t17-,18-/m1/s1	BNIBDNOALUGLCI-PJHKVULZSA-N	50014669	6-[2-(4'-Fluoro-3,5,3'-trimethyl-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL440891	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 7.00							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014669&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			6439709	103926564		CHEMBL440891				ZINC06069734	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50612153	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1ccc(F)cc1	InChI=1S/C19H15Cl2FO3/c20-12-7-17(11-1-3-13(22)4-2-11)16(18(21)8-12)6-5-15-9-14(23)10-19(24)25-15/h1-8,14-15,23H,9-10H2/b6-5+/t14-,15-/m1/s1	VMMVXGKAALDTIC-XEVLESSRSA-N	50024972	(+) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::(-) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368970	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024972&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			12802879	103934942		CHEMBL2368970				ZINC29480073	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50612154	O[C@@H]1C[C@H](OC(=O)C1)\C=C\c1c(Cl)cc(Cl)cc1-c1ccc(F)cc1	InChI=1S/C19H15Cl2FO3/c20-12-7-17(11-1-3-13(22)4-2-11)16(18(21)8-12)6-5-15-9-14(23)10-19(24)25-15/h1-8,14-15,23H,9-10H2/b6-5+/t14-,15-/m1/s1	VMMVXGKAALDTIC-XEVLESSRSA-N	50024972	(+) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::(-) 6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::6-[2-(3,5-Dichloro-4''-fluoro-biphenyl-2-yl)-vinyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL2368970	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5.00							ChEMBL	10.1021/jm00152a002	10.7270/Q2RV0MQX	3950902			Stokker, GE; Alberts, AW; Anderson, PS; Cragoe, EJ; Deana, AA; Gilfillan, JL; Hirshfield, J; Holtz, WJ; Hoffman, WF; Huff, JW	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50024972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50024972&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			12802879	103934942		CHEMBL2368970				ZINC29480073	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030152	CCC(CC)(CC)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C27H42O5/c1-6-27(7-2,8-3)26(30)32-23-14-17(4)13-19-10-9-18(5)22(25(19)23)12-11-21-15-20(28)16-24(29)31-21/h9-10,13,17-18,20-23,25,28H,6-8,11-12,14-16H2,1-5H3/t17-,18-,20+,21+,22-,23-,25?/m0/s1	YNAMVFSBFMILIU-RRGHRAMSSA-N	50226270	CHEMBL3349956	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.4							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226270&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718664	378166747		CHEMBL3349956					1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030153	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19?,20-,21-,23?/m0/s1	PCZOHLXUXFIOCF-QBVZFDLDSA-N	50003235	2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester::2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester: 0.1C4H9Cl::BDBM50226269::CHEMBL333443	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.2							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50003235	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50003235&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			9865943	103917215		CHEMBL79583CHEMBL333443				ZINC14984346	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030154	CCCC(CC)(CC)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C28H44O5/c1-6-13-28(7-2,8-3)27(31)33-24-15-18(4)14-20-10-9-19(5)23(26(20)24)12-11-22-16-21(29)17-25(30)32-22/h9-10,14,18-19,21-24,26,29H,6-8,11-13,15-17H2,1-5H3/t18-,19-,21+,22+,23-,24-,26?/m0/s1	KLHKBEUARNHSAF-JXKGLIOISA-N	50226271	CHEMBL3349955	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.9							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226271	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226271&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718663	378166748		CHEMBL3349955					1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50030155	CCC(C)(CC)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)C12	InChI=1S/C26H40O5/c1-6-26(5,7-2)25(29)31-22-13-16(3)12-18-9-8-17(4)21(24(18)22)11-10-20-14-19(27)15-23(28)30-20/h8-9,12,16-17,19-22,24,27H,6-7,10-11,13-15H2,1-5H3/t16-,17-,19+,20+,21-,22-,24?/m0/s1	OKOKBYYKKPVXFH-UCQOJCJXSA-N	50226272	CHEMBL3349944	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1.4							ChEMBL	10.1021/jm00155a040	10.7270/Q2BZ652M	3634830			Hoffman, WF; Alberts, AW; Anderson, PS; Chen, JS; Smith, RL; Willard, AK	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50226272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50226272&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			118718652	378166749		CHEMBL3349944					1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032391	Cc1ccc(-c2cccc(c2)C(F)(F)F)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H20F3NO3/c1-12-5-6-17(13-3-2-4-14(9-13)19(20,21)22)23(12)8-7-16-10-15(24)11-18(25)26-16/h2-6,9,15-16,24H,7-8,10-11H2,1H3/t15-,16-/m1/s1	FDQMBHADFAULHR-HZPDHXFCSA-N	50014674	4-Hydroxy-6-{2-[2-methyl-5-(3-trifluoromethyl-phenyl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL321564	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 1500							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014674&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335890	103926569		CHEMBL321564				ZINC26835097	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032394	O[C@@H]1C[C@@H](CCn2c(ccc2-c2ccc(F)cc2)C2CCCCC2)OC(=O)C1	InChI=1S/C23H28FNO3/c24-18-8-6-17(7-9-18)22-11-10-21(16-4-2-1-3-5-16)25(22)13-12-20-14-19(26)15-23(27)28-20/h6-11,16,19-20,26H,1-5,12-15H2/t19-,20-/m1/s1	CQLCSKXQNGSOLY-WOJBJXKFSA-N	50014681	6-{2-[2-Cyclohexyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322367	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		>100000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014681&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335592	103926576		CHEMBL322367				ZINC26836770	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032397	Cc1ccc(C2CC3CC2C=C3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H25NO3/c1-12-2-5-18(17-9-13-3-4-14(17)8-13)20(12)7-6-16-10-15(21)11-19(22)23-16/h2-5,13-17,21H,6-11H2,1H3/t13?,14?,15-,16-,17?/m1/s1	IHNCWQSEFKFQIZ-VHUWHVEYSA-N	50014688	6-[2-(2-Bicyclo[2.2.1]hept-5-en-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL321914	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5800							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014688&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785456	103926583		CHEMBL321914				ZINC26839261	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032400	O[C@@H]1C[C@@H](CCn2c(ccc2-c2ccc(F)cc2)C2CC2)OC(=O)C1	InChI=1S/C20H22FNO3/c21-15-5-3-14(4-6-15)19-8-7-18(13-1-2-13)22(19)10-9-17-11-16(23)12-20(24)25-17/h3-8,13,16-17,23H,1-2,9-12H2/t16-,17-/m1/s1	YXISEZLIKDLBHD-IAGOWNOFSA-N	50014695	6-{2-[2-Cyclopropyl-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL106062	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2600							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014695&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335566	103926590		CHEMBL106062				ZINC26832445	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032401	COc1ccc2ccccc2c1-c1ccc(C(C)C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H29NO4/c1-16(2)21-9-10-22(26(21)13-12-19-14-18(27)15-24(28)30-19)25-20-7-5-4-6-17(20)8-11-23(25)29-3/h4-11,16,18-19,27H,12-15H2,1-3H3/t18-,19-/m1/s1	WFMHEDHHCWBSIB-RTBURBONSA-N	50014699	4-Hydroxy-6-{2-[2-isopropyl-5-(2-methoxy-naphthalen-1-yl)-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one::CHEMBL104639	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014699&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335605	103926594		CHEMBL104639				ZINC26834871	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032402	CCC(CC)c1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H28FNO3/c1-3-15(4-2)20-9-10-21(16-5-7-17(23)8-6-16)24(20)12-11-19-13-18(25)14-22(26)27-19/h5-10,15,18-19,25H,3-4,11-14H2,1-2H3/t18-,19-/m1/s1	OOANXJFGKWCWIB-RTBURBONSA-N	50014697	6-{2-[2-(1-Ethyl-propyl)-5-(4-fluoro-phenyl)-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL321930	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 32000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014697&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335567	103926592		CHEMBL321930				ZINC26832449	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032403	Cc1ccc(-c2ccc3ccccc3c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H23NO3/c1-15-6-9-21(18-8-7-16-4-2-3-5-17(16)12-18)23(15)11-10-20-13-19(24)14-22(25)26-20/h2-9,12,19-20,24H,10-11,13-14H2,1H3/t19-,20-/m1/s1	YAGSCRJOPNSMPV-WOJBJXKFSA-N	50014696	4-Hydroxy-6-[2-(2-methyl-5-naphthalen-2-yl-pyrrol-1-yl)-ethyl]-tetrahydro-pyran-2-one::CHEMBL317885	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3981							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014696&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785454	103926591		CHEMBL317885				ZINC26834167	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032408	Cc1ccc(C2CC3CCC2CC3)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H29NO3/c1-13-2-7-19(18-10-14-3-5-15(18)6-4-14)21(13)9-8-17-11-16(22)12-20(23)24-17/h2,7,14-18,22H,3-6,8-12H2,1H3/t14?,15?,16-,17-,18?/m1/s1	JLQQCFATUIPBTG-PXUJOYAKSA-N	50014698	6-[2-(2-Bicyclo[2.2.2]oct-2-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL265305	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2512							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014698&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335733	103926593		CHEMBL265305				ZINC26834164	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032410	Cc1ccc(C(c2ccccc2)c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C25H27NO3/c1-18-12-13-23(26(18)15-14-22-16-21(27)17-24(28)29-22)25(19-8-4-2-5-9-19)20-10-6-3-7-11-20/h2-13,21-22,25,27H,14-17H2,1H3/t21-,22-/m1/s1	ZYOUITAWBXBZCC-FGZHOGPDSA-N	50014689	6-[2-(2-Benzhydryl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104703	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 13000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014689&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785458	103926584		CHEMBL104703				ZINC26837186	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032412	COc1cccc(c1)-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-6-7-18(14-4-3-5-16(10-14)23-2)20(13)9-8-17-11-15(21)12-19(22)24-17/h3-7,10,15,17,21H,8-9,11-12H2,1-2H3/t15-,17-/m1/s1	ZUJYBBIDWOTFNW-NVXWUHKLSA-N	50014678	CHEMBL104866::i4-Hydroxy-6-{2-[2-(3-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 10000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014678&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335855	103926573		CHEMBL104866				ZINC26835999	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032413	Cc1ccc(-c2ccc(F)cc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C18H20FNO3/c1-12-2-7-17(13-3-5-14(19)6-4-13)20(12)9-8-16-10-15(21)11-18(22)23-16/h2-7,15-16,21H,8-11H2,1H3/t15-,16-/m1/s1	QNKLRMPQOSICFR-HZPDHXFCSA-N	50014683	CHEMBL104660::i6-{2-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2512							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014683&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			18606835	103926578		CHEMBL104660				ZINC26838114	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032414	O[C@@H]1C[C@@H](CCn2c(ccc2C(F)(F)F)-c2ccc(F)cc2)OC(=O)C1	InChI=1S/C18H17F4NO3/c19-12-3-1-11(2-4-12)15-5-6-16(18(20,21)22)23(15)8-7-14-9-13(24)10-17(25)26-14/h1-6,13-14,24H,7-10H2/t13-,14-/m1/s1	WWKQYHAFGOBLDP-ZIAGYGMSSA-N	50014667	6-{2-[2-(4-Fluoro-phenyl)-5-trifluoromethyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322366	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 250							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014667&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335591	103926562		CHEMBL322366				ZINC26836766	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032415	Cc1ccc(-c2ccc(cc2)-c2ccccc2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C24H25NO3/c1-17-7-12-23(25(17)14-13-22-15-21(26)16-24(27)28-22)20-10-8-19(9-11-20)18-5-3-2-4-6-18/h2-12,21-22,26H,13-16H2,1H3/t21-,22-/m1/s1	NSUYYCLWHSMXLG-FGZHOGPDSA-N	50014675	6-[2-(2-Biphenyl-4-yl-5-methyl-pyrrol-1-yl)-ethyl]-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL107995	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25119							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014675&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			13785450	103926570		CHEMBL107995				ZINC26839318	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032416	CC(C)c1ccc(-c2cccc(F)c2)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24FNO3/c1-13(2)18-6-7-19(14-4-3-5-15(21)10-14)22(18)9-8-17-11-16(23)12-20(24)25-17/h3-7,10,13,16-17,23H,8-9,11-12H2,1-2H3/t16-,17-/m1/s1	AHVDPZLQANCRDN-IAGOWNOFSA-N	50014671	6-{2-[2-(3-Fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL104295	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2600							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014671&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335590	103926566		CHEMBL104295				ZINC26836762	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032417	CC(C)c1ccc(-c2ccccc2Cl)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24ClNO3/c1-13(2)18-7-8-19(16-5-3-4-6-17(16)21)22(18)10-9-15-11-14(23)12-20(24)25-15/h3-8,13-15,23H,9-12H2,1-2H3/t14-,15-/m1/s1	HKCTYZKXOAMQGS-HUUCEWRRSA-N	50014670	6-{2-[2-(2-Chloro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322724	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3162							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014670&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335617	103926565		CHEMBL322724				ZINC26839399	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032418	Cc1ccc(-c2ccc(F)cc2)n1-c1cccc(c1)[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H20FNO3/c1-14-5-10-20(15-6-8-17(23)9-7-15)24(14)18-4-2-3-16(11-18)21-12-19(25)13-22(26)27-21/h2-11,19,21,25H,12-13H2,1H3/t19-,21+/m1/s1	NRTHZCAQMYJGGO-CTNGQTDRSA-N	50014692	6-{3-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL105511	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 25119							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014692&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335495	103926587		CHEMBL105511				ZINC26836203	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032419	CC(C)c1ccc(-c2ccccc2Cl)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C20H24ClNO3/c1-13(2)18-7-8-19(16-5-3-4-6-17(16)21)22(18)10-9-15-11-14(23)12-20(24)25-15/h3-8,13-15,23H,9-12H2,1-2H3/t14-,15-/m1/s1	HKCTYZKXOAMQGS-HUUCEWRRSA-N	50014670	6-{2-[2-(2-Chloro-phenyl)-5-isopropyl-pyrrol-1-yl]-ethyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322724	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 3200							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014670&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335617	103926565		CHEMBL322724				ZINC26839399	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032420	Cc1ccc(-c2ccc(F)cc2)n1-c1ccc(cc1)[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C22H20FNO3/c1-14-2-11-20(15-3-7-17(23)8-4-15)24(14)18-9-5-16(6-10-18)21-12-19(25)13-22(26)27-21/h2-11,19,21,25H,12-13H2,1H3/t19-,21+/m1/s1	AJEIONSXDYSIJV-CTNGQTDRSA-N	50014705	6-{4-[2-(4-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-4-hydroxy-tetrahydro-pyran-2-one::CHEMBL322874	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 20000							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014705&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335494	103926600		CHEMBL322874				ZINC26836199	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50032421	COc1cccc(c1)-c1ccc(C)n1CC[C@@H]1C[C@@H](O)CC(=O)O1	InChI=1S/C19H23NO4/c1-13-6-7-18(14-4-3-5-16(10-14)23-2)20(13)9-8-17-11-15(21)12-19(22)24-17/h3-7,10,15,17,21H,8-9,11-12H2,1-2H3/t15-,17-/m1/s1	ZUJYBBIDWOTFNW-NVXWUHKLSA-N	50014678	CHEMBL104866::i4-Hydroxy-6-{2-[2-(3-methoxy-phenyl)-5-methyl-pyrrol-1-yl]-ethyl}-tetrahydro-pyran-2-one	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2500							ChEMBL	10.1021/jm00163a005	10.7270/Q2XG9RR6	2296019			Roth, BD; Ortwine, DF; Hoefle, ML; Stratton, CD; Sliskovic, DR; Wilson, MW; Newton, RS	Warner-Lambert Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50014678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50014678&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			44335855	103926573		CHEMBL104866				ZINC26835999	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50019369	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(cn1C(C)C)-c1ccc(F)cc1	InChI=1S/C23H32FNO4/c1-14(2)23-20(10-9-18(26)11-19(27)12-22(28)29)21(13-25(23)15(3)4)16-5-7-17(24)8-6-16/h5-8,13-15,18-19,26-27H,9-12H2,1-4H3,(H,28,29)/p-1/t18-,19-/m1/s1	VJZPFDQBVJSLEQ-RTBURBONSA-M	50013216	(racemic)Sodium salt of7-[4-(4-Fluoro-phenyl)-1,2-diisopropyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoic acid::CHEMBL348798::Sodium salt of7-[4-(4-Fluoro-phenyl)-1,2-diisopropyl-1H-pyrrol-3-yl]-3R,5R-dihydroxy-heptanoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 18							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013216&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			91928864	103925431		CHEMBL348798			C03834	ZINC13887138	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
50627945	CC(C)c1c(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c(c(C)n1-c1ccccc1)-c1ccc(F)cc1	InChI=1S/C27H32FNO4/c1-17(2)27-24(14-13-22(30)15-23(31)16-25(32)33)26(19-9-11-20(28)12-10-19)18(3)29(27)21-7-5-4-6-8-21/h4-12,17,22-23,30-31H,13-16H2,1-3H3,(H,32,33)/p-1/t22-,23-/m1/s1	JHURQXGATCGLIV-DHIUTWEWSA-M	50013214	(racemic)Sodium salt of7-[4-(4-Fluoro-phenyl)-2-isopropyl-5-methyl-1-phenyl-1H-pyrrol-3-yl]-3,5-dihydroxy-heptanoic acid::CHEMBL436037::Sodium salt of7-[4-(4-Fluoro-phenyl)-2-isopropyl-5-methyl-1-phenyl-1H-pyrrol-3-yl]-3R,5R-dihydroxy-heptanoic acid	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 5.00							ChEMBL	10.1021/jm00163a011	10.7270/Q22V2F4S	2153213			Jendralla, H; Baader, E; Bartmann, W; Beck, G; Bergmann, A; Granzer, E; von Kerekjarto, B; Kesseler, K; Krause, R; Schubert, W	Hoechst AG	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50013214	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50013214&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			56947028	103925429		CHEMBL436037			C03834	ZINC27747847	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
51519677	CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1	PCZOHLXUXFIOCF-BXMDZJJMSA-N	34168	LOVASTATIN::MLS000069585::SMR000058779::US9115116, lovastatin::US9353061, Lovastatina::cid_53232	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 2.2							ChEMBL		10.7270/Q2JH3RDC	30243589			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34168	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34168&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	803	1CQP,7KC6	53232	252616855	40303		DB00227	2739	C07074	ZINC03812841	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6						
51519678	CCC(C)(C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12	InChI=1S/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1	RYMZZMVNJRMUDD-HGQWONQESA-N	50139181	(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate::2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one::MK-733::SIMVASTATIN LACTONE::Simvastatin::Zocor::cid_54454	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Rattus norvegicus		 0.900000							ChEMBL		10.7270/Q2JH3RDC	30243589			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2085&target=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139181&enzyme=3-hydroxy-3-methylglutaryl-coenzyme+A+reductase&column=ki&startPg=0&Increment=50&submit=Search			54454	104029076	9150		DB00641	2955		ZINC03780893	1	MLSRLFRMHGLFVASHPWEVIVGTVTLTICMMSMNMFTGNNKICGWNYECPKFEEDVLSSDIIILTITRCIAILYIYFQFQNLRQLGSKYILGIAGLFTIFSSFVFSTVVIHFLDKELTGLNEALPFFLLLIDLSRASALAKFALSSNSQDEVRENIARGMAILGPTFTLDALVECLVIGVGTMSGVRQLEIMCCFGCMSVLANYFVFMTFFPACVSLVLELSRESREGRPIWQLSHFARVLEEEENKPNPVTQRVKMIMSLGLVLVHAHSRWIADPSPQNSTAEQSKVSLGLAEDVSKRIEPSVSLWQFYLSKMISMDIEQVITLSLALLLAVKYIFFEQAETESTLSLKNPITSPVVTPKKAQDNCCRREPLLVRRNQKLSSVEEDPGVNQDRKVEVIKPLVAEAETSGRATFVLGASAASPPLALGAQEPGIELPSEPRPNEECLQILESAEKGAKFLSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSAKLAEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDGKEYQVPMATTEGCLVASTNRGCRAISLGGGASSRVLADGMSRGPVVRLPRACDSAEVKSWLETPEGFAVVKEAFDSTSRFARLQKLHVTLAGRNLYIRLQSKTGDAMGMNMISKGTEKALLKLQEFFPELQILAVSGNYCTDKKPAAINWIEGRGKTVVCEAVIPAKVVREVLKTTTEAMVDVNINKNLVGSAMAGSIGGYNAHAANIVTAIYIACGQDAAQNVGSSNCITLMEASGPTNEDLYISCTMPSIEIGTVGGGTNLLPQQACLQMLGVQGACKDNPGENARQLARIVCGTVMAGELSLMAALAAGHLVRSHMVHNRSKINLQDLQGTCTKKAA		3-hydroxy-3-methylglutaryl-coenzyme A reductase	HMDH_RAT	P51639	Q64601 Q6P2A6