BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 36215 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta [154-461] Homo sapiens 12 410 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36216 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta [154-461] Homo sapiens 10 16 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36217 FC(F)(F)c1cccc2c(-c3ccccc3)c(cnc12)C(=O)c1ccccc1 InChI=1S/C23H14F3NO/c24-23(25,26)19-13-7-12-17-20(15-8-3-1-4-9-15)18(14-27-21(17)19)22(28)16-10-5-2-6-11-16/h1-14H VLCMRTMCMQJSKM-UHFFFAOYSA-N 19994 3-benzoyl-4-phenyl-8-(trifluoromethyl)quinoline::Quinoline 4::phenyl-[4-phenyl-8-(trifluoromethyl)quinolin-3-yl]methanone Oxysterols receptor LXR-beta [154-461] Homo sapiens 107 1400 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19994&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 11360909 46519989 ZINC14972465 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36218 OC(=O)c1ccc(COc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C31H20F3NO4/c32-31(33,34)26-11-5-10-24-27(25(17-35-28(24)26)29(36)20-6-2-1-3-7-20)22-8-4-9-23(16-22)39-18-19-12-14-21(15-13-19)30(37)38/h1-17H,18H2,(H,37,38) NDCQPJCNZBQYAO-UHFFFAOYSA-N 19995 4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}benzoic acid::Quinoline 10 Oxysterols receptor LXR-beta [154-461] Homo sapiens 67 186 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19995&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 11261037 46519990 ZINC14972469 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36219 COC(=O)c1ccc(COc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C32H22F3NO4/c1-39-31(38)22-15-13-20(14-16-22)19-40-24-10-5-9-23(17-24)28-25-11-6-12-27(32(33,34)35)29(25)36-18-26(28)30(37)21-7-3-2-4-8-21/h2-18H,19H2,1H3 DYXKUMACGJLDGE-UHFFFAOYSA-N 19996 Quinoline 11::methyl 4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}benzoate Oxysterols receptor LXR-beta [154-461] Homo sapiens >1000 296 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19996&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16090326 46519991 ZINC14972473 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36220 OC(=O)c1cccc(COc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)c1 InChI=1S/C31H20F3NO4/c32-31(33,34)26-14-6-13-24-27(25(17-35-28(24)26)29(36)20-8-2-1-3-9-20)21-10-5-12-23(16-21)39-18-19-7-4-11-22(15-19)30(37)38/h1-17H,18H2,(H,37,38) BXYZFBZFOPCYGD-UHFFFAOYSA-N 19997 3-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}benzoic acid::Quinoline 12 Oxysterols receptor LXR-beta [154-461] Homo sapiens 1033 1500 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19997&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16090327 46519992 ZINC14972477 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36221 OC(=O)c1ccc(COc2ccc(cc2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C31H20F3NO4/c32-31(33,34)26-8-4-7-24-27(25(17-35-28(24)26)29(36)21-5-2-1-3-6-21)20-13-15-23(16-14-20)39-18-19-9-11-22(12-10-19)30(37)38/h1-17H,18H2,(H,37,38) PNGPMNXTYUTTTK-UHFFFAOYSA-N 19998 4-{4-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}benzoic acid::Quinoline 13 Oxysterols receptor LXR-beta [154-461] Homo sapiens 2738 1500 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19998&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16090328 46519993 ZINC14972480 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36222 OC(=O)Cc1ccc(COc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C32H22F3NO4/c33-32(34,35)27-11-5-10-25-29(26(18-36-30(25)27)31(39)22-6-2-1-3-7-22)23-8-4-9-24(17-23)40-19-21-14-12-20(13-15-21)16-28(37)38/h1-15,17-18H,16,19H2,(H,37,38) YAKODSHNCZYDPB-UHFFFAOYSA-N 19999 2-(4-{3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid::Quinoline 14 Oxysterols receptor LXR-beta [154-461] Homo sapiens 5 143 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19999&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16090329 46519994 C03768 ZINC14972484 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36223 OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H24F3NO3/c33-32(34,35)28-11-5-10-27-30(25(19-36-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)39-20-23-14-12-22(13-15-23)17-29(37)38/h1-15,18-19H,16-17,20H2,(H,37,38) VXHRQVMQVYQGQG-UHFFFAOYSA-N 20000 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid::CHEMBL214719::JMC496151 Compound 15::WAY-254011 Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.1 71 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20000&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search KVB 6S4T 11627859 46519995 CHEMBL214719 C03768 ZINC14972488 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36224 OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-27-30(25(20-37-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)36-19-23-14-12-22(13-15-23)17-29(38)39/h1-15,18,20,36H,16-17,19H2,(H,38,39) AVHJCISEWCJAIL-UHFFFAOYSA-N 20001 2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid::BMC153321 Compound 4::JMC517161 Compound 4::Quinoline 16 Oxysterols receptor LXR-beta [154-461] Homo sapiens 1.9 33 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20001&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16090330 46519996 C03768 ZINC14972492 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36225 OC(=O)Cc1ccc(NCc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-27-30(25(20-37-31(27)28)16-21-6-2-1-3-7-21)24-9-4-8-23(17-24)19-36-26-14-12-22(13-15-26)18-29(38)39/h1-15,17,20,36H,16,18-19H2,(H,38,39) SENBJMMSGVHUDH-UHFFFAOYSA-N 20002 2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}methyl)amino]phenyl}acetic acid::CHEMBL216645::Quinoline 17 Oxysterols receptor LXR-beta [154-461] Homo sapiens 7 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20002&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16090331 46519997 CHEMBL216645 C03768 ZINC14972496 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36226 CN(Cc1ccc(CC(O)=O)cc1)c1cccc(c1)-c1c(Cc2ccccc2)cnc2c(cccc12)C(F)(F)F InChI=1S/C33H27F3N2O2/c1-38(21-24-15-13-23(14-16-24)18-30(39)40)27-10-5-9-25(19-27)31-26(17-22-7-3-2-4-8-22)20-37-32-28(31)11-6-12-29(32)33(34,35)36/h2-16,19-20H,17-18,21H2,1H3,(H,39,40) TZRCVICHXMBFCB-UHFFFAOYSA-N 20003 2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}(methyl)amino)methyl]phenyl}acetic acid::Quinoline 18 Oxysterols receptor LXR-beta [154-461] Homo sapiens 115 374 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm0609566 10.7270/Q20863KH 17034119 aid1797933 Hu, B; Collini, M; Unwalla, R; Miller, C; Singhaus, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Resmini, C; Liu, QY; Feingold, I; Huselton, C; Azam, F; Farnegardh, M; Enroth, C; Bonn, T; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20003&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16090332 46519998 C03768 ZINC14972500 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36254 OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-27-30(25(20-37-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)36-19-23-14-12-22(13-15-23)17-29(38)39/h1-15,18,20,36H,16-17,19H2,(H,38,39) AVHJCISEWCJAIL-UHFFFAOYSA-N 20001 2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid::BMC153321 Compound 4::JMC517161 Compound 4::Quinoline 16 Oxysterols receptor LXR-beta [154-461] Homo sapiens 1.9 33 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20001&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16090330 46519996 C03768 ZINC14972492 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36255 OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C32H23F3N2O3/c33-32(34,35)27-11-5-10-25-29(26(19-37-30(25)27)31(40)22-6-2-1-3-7-22)23-8-4-9-24(17-23)36-18-21-14-12-20(13-15-21)16-28(38)39/h1-15,17,19,36H,16,18H2,(H,38,39) QMAWFUWIOSWDJM-UHFFFAOYSA-N 20004 2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid::phenyl acetic acid based quinoline, 16 Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.4 29 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20004&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 11191949 46519999 C03768 ZINC14972504 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36256 Cc1cnc2c(cccc2c1-c1cccc(NCc2ccc(CC(O)=O)cc2)c1)C(F)(F)F InChI=1S/C26H21F3N2O2/c1-16-14-31-25-21(6-3-7-22(25)26(27,28)29)24(16)19-4-2-5-20(13-19)30-15-18-10-8-17(9-11-18)12-23(32)33/h2-11,13-14,30H,12,15H2,1H3,(H,32,33) OEDBWXLEGYGITE-UHFFFAOYSA-N 20005 2-{4-[({3-[3-methyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid::phenyl acetic acid based quinoline, 17 Oxysterols receptor LXR-beta [154-461] Homo sapiens 4.3 100 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20005&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648467 46520000 C03768 ZINC14972508 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36257 OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)-c2ccccc2)cc1 InChI=1S/C31H23F3N2O2/c32-31(33,34)27-11-5-10-25-29(26(19-36-30(25)27)22-6-2-1-3-7-22)23-8-4-9-24(17-23)35-18-21-14-12-20(13-15-21)16-28(37)38/h1-15,17,19,35H,16,18H2,(H,37,38) FWTLKBYOKWCAEO-UHFFFAOYSA-N 20006 2-{4-[({3-[3-phenyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid::phenyl acetic acid based quinoline, 18 Oxysterols receptor LXR-beta [154-461] Homo sapiens 3.7 44 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20006&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648468 46520001 C03768 ZINC14972512 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36258 OC(c1ccccc1)c1cnc2c(cccc2c1-c1cccc(NCc2ccc(CC(O)=O)cc2)c1)C(F)(F)F InChI=1S/C32H25F3N2O3/c33-32(34,35)27-11-5-10-25-29(26(19-37-30(25)27)31(40)22-6-2-1-3-7-22)23-8-4-9-24(17-23)36-18-21-14-12-20(13-15-21)16-28(38)39/h1-15,17,19,31,36,40H,16,18H2,(H,38,39) FLJYMVVOBYULHJ-UHFFFAOYSA-N 20007 2-(4-{[(3-{3-[hydroxy(phenyl)methyl]-8-(trifluoromethyl)quinolin-4-yl}phenyl)amino]methyl}phenyl)acetic acid::phenyl acetic acid based quinoline, 19 Oxysterols receptor LXR-beta [154-461] Homo sapiens 56.4 812 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20007&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648469 46520002 C03768 ZINC14972521 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36259 OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C#N)cc1 InChI=1S/C26H18F3N3O2/c27-26(28,29)22-6-2-5-21-24(19(13-30)15-32-25(21)22)18-3-1-4-20(12-18)31-14-17-9-7-16(8-10-17)11-23(33)34/h1-10,12,15,31H,11,14H2,(H,33,34) YNYIBKWUFCUQQY-UHFFFAOYSA-N 20008 2-{4-[({3-[3-cyano-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid::phenyl acetic acid based quinoline, 20 Oxysterols receptor LXR-beta [154-461] Homo sapiens 33.8 450 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20008&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648470 46520003 C03768 ZINC14972525 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36260 NC(=O)c1cnc2c(cccc2c1-c1cccc(NCc2ccc(CC(O)=O)cc2)c1)C(F)(F)F InChI=1S/C26H20F3N3O3/c27-26(28,29)21-6-2-5-19-23(20(25(30)35)14-32-24(19)21)17-3-1-4-18(12-17)31-13-16-9-7-15(8-10-16)11-22(33)34/h1-10,12,14,31H,11,13H2,(H2,30,35)(H,33,34) WYSNMXQODNGIQW-UHFFFAOYSA-N 20009 2-{4-[({3-[3-carbamoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid::phenyl acetic acid based quinoline, 21 Oxysterols receptor LXR-beta [154-461] Homo sapiens >10000 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20009&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648471 46520004 C03768 ZINC14972529 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36261 Cc1cccc2c(-c3cccc(NCc4ccc(CC(O)=O)cc4)c3)c(cnc12)C(=O)c1ccccc1 InChI=1S/C32H26N2O3/c1-21-7-5-12-27-30(28(20-34-31(21)27)32(37)24-8-3-2-4-9-24)25-10-6-11-26(18-25)33-19-23-15-13-22(14-16-23)17-29(35)36/h2-16,18,20,33H,17,19H2,1H3,(H,35,36) AJSJAQQMFKYODQ-UHFFFAOYSA-N 20010 2-[4-({[3-(3-benzoyl-8-methylquinolin-4-yl)phenyl]amino}methyl)phenyl]acetic acid::phenyl acetic acid based quinoline, 22 Oxysterols receptor LXR-beta [154-461] Homo sapiens 5.5 61 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20010&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648472 46520005 C03768 ZINC14972533 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36262 Cc1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(NCc2ccc(CC(O)=O)cc2)c1 InChI=1S/C32H28N2O2/c1-22-7-5-12-29-31(27(21-34-32(22)29)17-23-8-3-2-4-9-23)26-10-6-11-28(19-26)33-20-25-15-13-24(14-16-25)18-30(35)36/h2-16,19,21,33H,17-18,20H2,1H3,(H,35,36) FVKYONNSLLCHIF-UHFFFAOYSA-N 20011 2-[4-({[3-(3-benzyl-8-methylquinolin-4-yl)phenyl]amino}methyl)phenyl]acetic acid::phenyl acetic acid based quinoline, 23 Oxysterols receptor LXR-beta [154-461] Homo sapiens 5.0 90 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20011&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16739344 46520006 C03768 ZINC14972537 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36263 OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(F)cccc23)C(=O)c2ccccc2)cc1 InChI=1S/C31H23FN2O3/c32-27-11-5-10-25-29(26(19-34-30(25)27)31(37)22-6-2-1-3-7-22)23-8-4-9-24(17-23)33-18-21-14-12-20(13-15-21)16-28(35)36/h1-15,17,19,33H,16,18H2,(H,35,36) XUAMCPQLEJKSQK-UHFFFAOYSA-N 20012 2-[4-({[3-(3-benzoyl-8-fluoroquinolin-4-yl)phenyl]amino}methyl)phenyl]acetic acid::phenyl acetic acid based quinoline, 24 Oxysterols receptor LXR-beta [154-461] Homo sapiens 17.0 700 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20012&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648473 46520007 C03768 ZINC14972541 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36264 OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3ccccc23)C(=O)c2ccccc2)cc1 InChI=1S/C31H24N2O3/c34-29(35)17-21-13-15-22(16-14-21)19-32-25-10-6-9-24(18-25)30-26-11-4-5-12-28(26)33-20-27(30)31(36)23-7-2-1-3-8-23/h1-16,18,20,32H,17,19H2,(H,34,35) CHCCPPPOKAASRP-UHFFFAOYSA-N 20013 2-[4-({[3-(3-benzoylquinolin-4-yl)phenyl]amino}methyl)phenyl]acetic acid::phenyl acetic acid based quinoline, 25 Oxysterols receptor LXR-beta [154-461] Homo sapiens 154 1650 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20013&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648474 46520008 C03768 ZINC14972545 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36265 OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(Cl)cccc23)C(=O)c2ccccc2)cc1 InChI=1S/C31H23ClN2O3/c32-27-11-5-10-25-29(26(19-34-30(25)27)31(37)22-6-2-1-3-7-22)23-8-4-9-24(17-23)33-18-21-14-12-20(13-15-21)16-28(35)36/h1-15,17,19,33H,16,18H2,(H,35,36) DIEQFJUHAMDHJZ-UHFFFAOYSA-N 20014 2-[4-({[3-(3-benzoyl-8-chloroquinolin-4-yl)phenyl]amino}methyl)phenyl]acetic acid::phenyl acetic acid based quinoline, 26 Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.7 39 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20014&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648475 46520009 C03768 ZINC14972549 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36266 OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(Cl)cccc23)cc1 InChI=1S/C31H25ClN2O2/c32-28-11-5-10-27-30(25(20-34-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)33-19-23-14-12-22(13-15-23)17-29(35)36/h1-15,18,20,33H,16-17,19H2,(H,35,36) MFLGRDLZNMSORM-UHFFFAOYSA-N 20015 2-[4-({[3-(3-benzyl-8-chloroquinolin-4-yl)phenyl]amino}methyl)phenyl]acetic acid::phenyl acetic acid based quinoline, 27 Oxysterols receptor LXR-beta [154-461] Homo sapiens 1.4 23 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20015&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648476 46520010 C03768 ZINC14972553 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36267 OC(=O)Cc1cccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)c1 InChI=1S/C32H23F3N2O3/c33-32(34,35)27-14-6-13-25-29(26(19-37-30(25)27)31(40)22-9-2-1-3-10-22)23-11-5-12-24(17-23)36-18-21-8-4-7-20(15-21)16-28(38)39/h1-15,17,19,36H,16,18H2,(H,38,39) TUYZXSLKXBNYSH-UHFFFAOYSA-N 20016 2-{3-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid::phenyl acetic acid based quinoline, 28 Oxysterols receptor LXR-beta [154-461] Homo sapiens 6.0 141 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20016&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648477 46520011 ZINC14972557 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36268 OC(=O)COc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C32H23F3N2O4/c33-32(34,35)27-11-5-10-25-29(26(18-37-30(25)27)31(40)21-6-2-1-3-7-21)22-8-4-9-23(16-22)36-17-20-12-14-24(15-13-20)41-19-28(38)39/h1-16,18,36H,17,19H2,(H,38,39) NXWUKMWXYWOKJK-UHFFFAOYSA-N 20017 2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenoxy}acetic acid::phenyl acetic acid based quinoline, 29 Oxysterols receptor LXR-beta [154-461] Homo sapiens 12 1271 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20017&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648478 46520012 ZINC14972560 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36269 OC(=O)\C=C\c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C33H23F3N2O3/c34-33(35,36)28-11-5-10-26-30(27(20-38-31(26)28)32(41)23-6-2-1-3-7-23)24-8-4-9-25(18-24)37-19-22-14-12-21(13-15-22)16-17-29(39)40/h1-18,20,37H,19H2,(H,39,40)/b17-16+ LNTBWVXFQSTLPE-WUKNDPDISA-N 20018 (2E)-3-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}prop-2-enoic acid::phenyl acetic acid based quinoline, 30 Oxysterols receptor LXR-beta [154-461] Homo sapiens >10000 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20018&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648479 46520013 ZINC14972564 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36270 OC(=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C31H21F3N2O3/c32-31(33,34)26-11-5-10-24-27(25(18-36-28(24)26)29(37)20-6-2-1-3-7-20)22-8-4-9-23(16-22)35-17-19-12-14-21(15-13-19)30(38)39/h1-16,18,35H,17H2,(H,38,39) WPUHRYSDQSXTGR-UHFFFAOYSA-N 20019 4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]benzoic acid::phenyl acetic acid based quinoline, 31 Oxysterols receptor LXR-beta [154-461] Homo sapiens 138 365 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20019&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648480 46520014 ZINC14972568 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36271 CC(C(O)=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C33H25F3N2O3/c1-20(32(40)41)22-15-13-21(14-16-22)18-37-25-10-5-9-24(17-25)29-26-11-6-12-28(33(34,35)36)30(26)38-19-27(29)31(39)23-7-3-2-4-8-23/h2-17,19-20,37H,18H2,1H3,(H,40,41) SQHRBEDYCPJCNA-UHFFFAOYSA-N 20020 2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}propanoic acid::phenyl acetic acid based quinoline, 32 Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.6 58 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20020&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648481 46520015 ZINC14972576 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36272 CC(C)(C(O)=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C34H27F3N2O3/c1-33(2,32(41)42)24-16-14-21(15-17-24)19-38-25-11-6-10-23(18-25)29-26-12-7-13-28(34(35,36)37)30(26)39-20-27(29)31(40)22-8-4-3-5-9-22/h3-18,20,38H,19H2,1-2H3,(H,41,42) CHDZBJMLJJYFFA-UHFFFAOYSA-N 20021 2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}-2-methylpropanoic acid::phenyl acetic acid based quinoline, 33 Oxysterols receptor LXR-beta [154-461] Homo sapiens 3.8 78 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20021&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648482 46520016 ZINC14972580 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36273 OC(C(O)=O)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C32H23F3N2O4/c33-32(34,35)26-11-5-10-24-27(25(18-37-28(24)26)29(38)20-6-2-1-3-7-20)22-8-4-9-23(16-22)36-17-19-12-14-21(15-13-19)30(39)31(40)41/h1-16,18,30,36,39H,17H2,(H,40,41) JLWYCHMJOLWTSZ-UHFFFAOYSA-N 20022 2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}-2-hydroxyacetic acid::phenyl acetic acid based quinoline, 34 Oxysterols receptor LXR-beta [154-461] Homo sapiens 8.5 4003 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20022&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648483 46520017 C02929 ZINC14972588 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36274 OC(=O)C(F)(F)c1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C32H21F5N2O3/c33-31(34,30(41)42)22-14-12-19(13-15-22)17-38-23-9-4-8-21(16-23)27-24-10-5-11-26(32(35,36)37)28(24)39-18-25(27)29(40)20-6-2-1-3-7-20/h1-16,18,38H,17H2,(H,41,42) DUOZJJLSLMAQCI-UHFFFAOYSA-N 20023 2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}-2,2-difluoroacetic acid::phenyl acetic acid based quinoline, 35 Oxysterols receptor LXR-beta [154-461] Homo sapiens 7.8 2395 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20023&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 11169139 46520018 ZINC14972592 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36275 NC(=O)Cc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C32H24F3N3O2/c33-32(34,35)27-11-5-10-25-29(26(19-38-30(25)27)31(40)22-6-2-1-3-7-22)23-8-4-9-24(17-23)37-18-21-14-12-20(13-15-21)16-28(36)39/h1-15,17,19,37H,16,18H2,(H2,36,39) JQOOZVXMCPGTNO-UHFFFAOYSA-N 20024 2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetamide::primary amide, 36 Oxysterols receptor LXR-beta [154-461] Homo sapiens 1.4 316 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20024&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648484 46520019 ZINC14972596 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36276 OCCc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-26-29(27(20-37-30(26)28)31(39)23-6-2-1-3-7-23)24-8-4-9-25(18-24)36-19-22-14-12-21(13-15-22)16-17-38/h1-15,18,20,36,38H,16-17,19H2 JNGMQNSQSCYLSD-UHFFFAOYSA-N 20025 2-{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}ethan-1-ol::ethanol analogue, 37 Oxysterols receptor LXR-beta [154-461] Homo sapiens 5.4 795 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20025&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648485 46520020 ZINC14972599 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36277 FC(F)(F)c1cccc2c(-c3cccc(NCc4ccccc4)c3)c(cnc12)C(=O)c1ccccc1 InChI=1S/C30H21F3N2O/c31-30(32,33)26-16-8-15-24-27(25(19-35-28(24)26)29(36)21-11-5-2-6-12-21)22-13-7-14-23(17-22)34-18-20-9-3-1-4-10-20/h1-17,19,34H,18H2 CUPCXDRVHZGUGE-UHFFFAOYSA-N 20026 3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]-N-benzylaniline::Quinoline 38 Oxysterols receptor LXR-beta [154-461] Homo sapiens 45 770 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20026&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648486 46520021 ZINC14972603 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36278 OCc1ccc(CNc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)C(=O)c2ccccc2)cc1 InChI=1S/C31H23F3N2O2/c32-31(33,34)27-11-5-10-25-28(26(18-36-29(25)27)30(38)22-6-2-1-3-7-22)23-8-4-9-24(16-23)35-17-20-12-14-21(19-37)15-13-20/h1-16,18,35,37H,17,19H2 QPTHELRQXXXGIF-UHFFFAOYSA-N 20027 methyl alcohol analogue,39::{4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}methanol Oxysterols receptor LXR-beta [154-461] Homo sapiens 12.8 2304 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20027&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648487 46520022 ZINC14972607 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36279 FC(F)(F)c1cccc2c(-c3cccc(NCc4ccc(\C=C5/SC(=O)NC5=O)cc4)c3)c(cnc12)C(=O)c1ccccc1 InChI=1S/C34H22F3N3O3S/c35-34(36,37)27-11-5-10-25-29(26(19-39-30(25)27)31(41)22-6-2-1-3-7-22)23-8-4-9-24(17-23)38-18-21-14-12-20(13-15-21)16-28-32(42)40-33(43)44-28/h1-17,19,38H,18H2,(H,40,42,43)/b28-16- JPIHSYRXQLKCID-NTFVMDSBSA-N 20028 (5Z)-5-({4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}methylidene)-1,3-thiazolidine-2,4-dione::(5Z)-5-{4-[({3-[3-Benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl} amino)methyl] benzylidene}-1,3-thiazolidine-2,4-dione::thiazolidine-2,4-dione, 40 Oxysterols receptor LXR-beta [154-461] Homo sapiens 276 369 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20028&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648488 46520023 ZINC14972611 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 36280 FC(F)(F)c1cccc2c(-c3cccc(NCc4ccc(\C=C5/SC(=S)NC5=O)cc4)c3)c(cnc12)C(=O)c1ccccc1 InChI=1S/C34H22F3N3O2S2/c35-34(36,37)27-11-5-10-25-29(26(19-39-30(25)27)31(41)22-6-2-1-3-7-22)23-8-4-9-24(17-23)38-18-21-14-12-20(13-15-21)16-28-32(42)40-33(43)44-28/h1-17,19,38H,18H2,(H,40,42,43)/b28-16- WXKZUGIMAGOYQL-NTFVMDSBSA-N 20029 (5Z)-5-({4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}methylidene)-2-sulfanylidene-1,3-thiazolidin-4-one::rhodanine, 41 Oxysterols receptor LXR-beta [154-461] Homo sapiens 310 286 Curated from the literature by BindingDB 10.1016/j.bmc.2007.03.013 10.7270/Q2VH5M37 17391964 aid1797934 Hu, B; Jetter, J; Kaufman, D; Singhaus, R; Bernotas, R; Unwalla, R; Quinet, E; Savio, D; Halpern, A; Basso, M; Keith, J; Clerin, V; Chen, L; Liu, QY; Feingold, I; Huselton, C; Azam, F; Goos-Nilsson, A; Wilhelmsson, A; Nambi, P; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20029&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 23648489 46520024 ZINC38377611 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47361 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta [154-461] Homo sapiens 9 170 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47362 OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40) NAXSRXHZFIBFMI-UHFFFAOYSA-N 19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2 Oxysterols receptor LXR-beta [154-461] Homo sapiens 12 310 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19992&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 965 3IPQ,1PQ6,4NQA 447905 46519987 CHEMBL59030 2754 C15631 ZINC24780352 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47363 OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H24F3NO3/c33-32(34,35)28-11-5-10-27-30(25(19-36-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)39-20-23-14-12-22(13-15-23)17-29(37)38/h1-15,18-19H,16-17,20H2,(H,37,38) VXHRQVMQVYQGQG-UHFFFAOYSA-N 20000 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid::CHEMBL214719::JMC496151 Compound 15::WAY-254011 Oxysterols receptor LXR-beta [154-461] Homo sapiens 2 90 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20000&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search KVB 6S4T 11627859 46519995 CHEMBL214719 C03768 ZINC14972488 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47364 OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-27-30(25(20-37-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)36-19-23-14-12-22(13-15-23)17-29(38)39/h1-15,18,20,36H,16-17,19H2,(H,38,39) AVHJCISEWCJAIL-UHFFFAOYSA-N 20001 2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}acetic acid::BMC153321 Compound 4::JMC517161 Compound 4::Quinoline 16 Oxysterols receptor LXR-beta [154-461] Homo sapiens 2 90 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20001&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16090330 46519996 C03768 ZINC14972492 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47365 FC(F)(F)c1cccc2c(-c3ccccc3)n(Cc3ccccc3)nc12 InChI=1S/C21H15F3N2/c22-21(23,24)18-13-7-12-17-19(18)25-26(14-15-8-3-1-4-9-15)20(17)16-10-5-2-6-11-16/h1-13H,14H2 LGRUCHCYEMOENE-UHFFFAOYSA-N 26064 2-benzyl-3-aryl-7-trifluoromethylindazole, 5::2-benzyl-3-phenyl-7-(trifluoromethyl)-2H-indazole Oxysterols receptor LXR-beta [154-461] Homo sapiens 41 3260 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26064&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137977 56464501 ZINC40874008 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47366 Cc1ccc(Cn2nc3c(cccc3c2-c2ccc(F)cc2)C(F)(F)F)c(C)c1 InChI=1S/C23H18F4N2/c1-14-6-7-17(15(2)12-14)13-29-22(16-8-10-18(24)11-9-16)19-4-3-5-20(21(19)28-29)23(25,26)27/h3-12H,13H2,1-2H3 XSNDTQOGMFODQY-UHFFFAOYSA-N 26065 2-[(2,4-dimethylphenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::2-benzyl-3-aryl-7-trifluoromethylindazole, 11 Oxysterols receptor LXR-beta [154-461] Homo sapiens 10 990 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26065&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137978 56464502 ZINC40391431 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47367 Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F InChI=1S/C21H12ClF5N2/c22-18-10-15(24)9-6-13(18)11-29-20(12-4-7-14(23)8-5-12)16-2-1-3-17(19(16)28-29)21(25,26)27/h1-10H,11H2 KYWWJENKIMRJBI-UHFFFAOYSA-N 26066 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::JMC517161 Compound 12::US10543183, Compound LXR-623::US10669296, Compound LXR-623::US10945978, Compound 3::WAY-252623 Oxysterols receptor LXR-beta [154-461] Homo sapiens 24 3670 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26066&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16734800 56464503 ZINC40379749 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47368 Fc1ccc(cc1)-c1n(Cc2ccccc2F)nc2c(cccc12)C(F)(F)F InChI=1S/C21H13F5N2/c22-15-10-8-13(9-11-15)20-16-5-3-6-17(21(24,25)26)19(16)27-28(20)12-14-4-1-2-7-18(14)23/h1-11H,12H2 NHSFDMDEDPAKNH-UHFFFAOYSA-N 26067 3-(4-fluorophenyl)-2-[(2-fluorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole::JMC517161 Compound 13::WAY-214950 Oxysterols receptor LXR-beta [154-461] Homo sapiens 33 4150 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26067&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25113722 56464504 ZINC40393236 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47369 Fc1ccc(cc1)-c1n(Cc2ccccc2Cl)nc2c(cccc12)C(F)(F)F InChI=1S/C21H13ClF4N2/c22-18-7-2-1-4-14(18)12-28-20(13-8-10-15(23)11-9-13)16-5-3-6-17(19(16)27-28)21(24,25)26/h1-11H,12H2 RGQJDOMXMZANLJ-UHFFFAOYSA-N 26068 2-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::2-benzyl-3-aryl-7-trifluoromethylindazole, 14 Oxysterols receptor LXR-beta [154-461] Homo sapiens 32 2890 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26068&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137979 56464505 ZINC40861331 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47370 Fc1ccc(Cn2nc3c(cccc3c2-c2ccc(F)cc2)C(F)(F)F)cc1 InChI=1S/C21H13F5N2/c22-15-8-4-13(5-9-15)12-28-20(14-6-10-16(23)11-7-14)17-2-1-3-18(19(17)27-28)21(24,25)26/h1-11H,12H2 BKPFNLPLHXLDDZ-UHFFFAOYSA-N 26069 2-benzyl-3-aryl-7-trifluoromethylindazole, 15::3-(4-fluorophenyl)-2-[(4-fluorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole Oxysterols receptor LXR-beta [154-461] Homo sapiens 49 5720 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26069&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137980 56464506 ZINC40393418 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47371 Fc1ccc(cc1)-c1n(Cc2ccc(Cl)cc2)nc2c(cccc12)C(F)(F)F InChI=1S/C21H13ClF4N2/c22-15-8-4-13(5-9-15)12-28-20(14-6-10-16(23)11-7-14)17-2-1-3-18(19(17)27-28)21(24,25)26/h1-11H,12H2 IOUQCKSTQUVCIP-UHFFFAOYSA-N 26070 2-[(4-chlorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole::2-benzyl-3-aryl-7-trifluoromethylindazole, 16 Oxysterols receptor LXR-beta [154-461] Homo sapiens 58 9050 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26070&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137981 56464507 ZINC40865176 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47372 Fc1cc(Cl)ccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F InChI=1S/C21H12Cl2F4N2/c22-14-7-4-12(5-8-14)20-16-2-1-3-17(21(25,26)27)19(16)28-29(20)11-13-6-9-15(23)10-18(13)24/h1-10H,11H2 KXXPROPFBQVDKT-UHFFFAOYSA-N 26071 2-[(4-chloro-2-fluorophenyl)methyl]-3-(4-chlorophenyl)-7-(trifluoromethyl)-2H-indazole::2-benzyl-3-aryl-7-trifluoromethylindazole, 17 Oxysterols receptor LXR-beta [154-461] Homo sapiens 38 9800 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26071&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137982 56464508 ZINC40423905 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47373 Fc1ccc(Cn2nc3c(cccc3c2-c2ccc(Cl)cc2)C(F)(F)F)c(Cl)c1 InChI=1S/C21H12Cl2F4N2/c22-14-7-4-12(5-8-14)20-16-2-1-3-17(21(25,26)27)19(16)28-29(20)11-13-6-9-15(24)10-18(13)23/h1-10H,11H2 IQTBHLOUVIJISQ-UHFFFAOYSA-N 26072 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-chlorophenyl)-7-(trifluoromethyl)-2H-indazole::2-benzyl-3-aryl-7-trifluoromethylindazole, 18 Oxysterols receptor LXR-beta [154-461] Homo sapiens 30 11220 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26072&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137983 56464509 ZINC42888320 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47374 FC(F)(F)c1cccc2c(-c3ccc(Cl)cc3)n(Cc3ccccc3Cl)nc12 InChI=1S/C21H13Cl2F3N2/c22-15-10-8-13(9-11-15)20-16-5-3-6-17(21(24,25)26)19(16)27-28(20)12-14-4-1-2-7-18(14)23/h1-11H,12H2 DTDVBYRJYQLMSF-UHFFFAOYSA-N 26073 2-benzyl-3-aryl-7-trifluoromethylindazole, 19::3-(4-chlorophenyl)-2-[(2-chlorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole Oxysterols receptor LXR-beta [154-461] Homo sapiens 40 10200 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26073&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137984 56464510 ZINC45497635 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47375 Fc1ccccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F InChI=1S/C21H13ClF4N2/c22-15-10-8-13(9-11-15)20-16-5-3-6-17(21(24,25)26)19(16)27-28(20)12-14-4-1-2-7-18(14)23/h1-11H,12H2 LMEZNWUTYWBWHN-UHFFFAOYSA-N 26074 2-benzyl-3-aryl-7-trifluoromethylindazole, 20::3-(4-chlorophenyl)-2-[(2-fluorophenyl)methyl]-7-(trifluoromethyl)-2H-indazole Oxysterols receptor LXR-beta [154-461] Homo sapiens 38 7440 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26074&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137985 56464511 ZINC40422553 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47376 FC(F)(F)c1ccccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F InChI=1S/C22H13ClF6N2/c23-15-10-8-13(9-11-15)20-16-5-3-7-18(22(27,28)29)19(16)30-31(20)12-14-4-1-2-6-17(14)21(24,25)26/h1-11H,12H2 CDLBQZJYZMCUBN-UHFFFAOYSA-N 26075 2-benzyl-3-aryl-7-trifluoromethylindazole, 21::3-(4-chlorophenyl)-7-(trifluoromethyl)-2-{[2-(trifluoromethyl)phenyl]methyl}-2H-indazole Oxysterols receptor LXR-beta [154-461] Homo sapiens 48 15460 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26075&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137986 56464512 ZINC40422862 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 47377 FC(F)(F)c1ccc(Cn2nc3c(cccc3c2-c2ccc(Cl)cc2)C(F)(F)F)cc1 InChI=1S/C22H13ClF6N2/c23-16-10-6-14(7-11-16)20-17-2-1-3-18(22(27,28)29)19(17)30-31(20)12-13-4-8-15(9-5-13)21(24,25)26/h1-11H,12H2 QHHCUPZYBPJZNN-UHFFFAOYSA-N 26076 2-benzyl-3-aryl-7-trifluoromethylindazole, 22::3-(4-chlorophenyl)-7-(trifluoromethyl)-2-{[4-(trifluoromethyl)phenyl]methyl}-2H-indazole Oxysterols receptor LXR-beta [154-461] Homo sapiens 1853 7.4 4.00 C Curated from the literature by BindingDB 10.1021/jm800799q 10.7270/Q2XW4H4G 18973288 aid1798629 Wrobel, J; Steffan†, R; Bowen, SM; Magolda, R; Matelan†, E; Unwalla†, R; Basso, M; Clerin, V; Gardell, SJ; Nambi, P; Quinet, E; Reminick, JI; Vlasuk, GP; Wang, S; Feingold, I; Huselton, C; Bonn, T Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26076&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 25137987 56464513 ZINC40423246 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62125 OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 SGIWFELWJPNFDH-UHFFFAOYSA-N 19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317 Oxysterols receptor LXR-beta [154-461] Homo sapiens 9 16 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19993&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 444 1UPV,1UPW,1PQC,5NTQ,4NB6,5K3L,1UHL,5EJV,2O9I 447912 46519988 CHEMBL62136 DB07080 2755 C15630 ZINC01550221 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62126 OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H24F3NO3/c33-32(34,35)28-11-5-10-27-30(25(19-36-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)39-20-23-14-12-22(13-15-23)17-29(37)38/h1-15,18-19H,16-17,20H2,(H,37,38) VXHRQVMQVYQGQG-UHFFFAOYSA-N 20000 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid::CHEMBL214719::JMC496151 Compound 15::WAY-254011 Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.1 71 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20000&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search KVB 6S4T 11627859 46519995 CHEMBL214719 C03768 ZINC14972488 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62127 COC(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C31H22F3NO3/c1-37-30(36)22-11-6-13-25(18-22)38-24-12-5-10-21(17-24)28-23(16-20-8-3-2-4-9-20)19-35-29-26(28)14-7-15-27(29)31(32,33)34/h2-15,17-19H,16H2,1H3 LJUJGMRQOWUZEL-UHFFFAOYSA-N 35087 BMC171663 Compound 4a::Benzylquinoline, 8a Oxysterols receptor LXR-beta [154-461] Homo sapiens 53 895 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35087&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472980 85753167 ZINC40401563 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62128 OCc1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C30H22F3NO2/c31-30(32,33)27-14-6-13-26-28(23(18-34-29(26)27)15-20-7-2-1-3-8-20)22-10-5-12-25(17-22)36-24-11-4-9-21(16-24)19-35/h1-14,16-18,35H,15,19H2 JZHGBILVGRSOHN-UHFFFAOYSA-N 35088 biarylether alcohol quinoline, 5a Oxysterols receptor LXR-beta [154-461] Homo sapiens 11.7 1030 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35088&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472981 85753168 ZINC45390969 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62129 CC(C)(O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C32H26F3NO2/c1-31(2,37)24-12-7-14-26(19-24)38-25-13-6-11-22(18-25)29-23(17-21-9-4-3-5-10-21)20-36-30-27(29)15-8-16-28(30)32(33,34)35/h3-16,18-20,37H,17H2,1-2H3 AIZFRFCHCJRXFS-UHFFFAOYSA-N 35089 biarylether alcohol quinoline, 5b Oxysterols receptor LXR-beta [154-461] Homo sapiens 3.3 31 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35089&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16727104 85753169 ZINC43168922 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62130 OCc1cccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)-c2ccccc2)c1 InChI=1S/C29H20F3NO2/c30-29(31,32)26-14-6-13-24-27(25(17-33-28(24)26)20-8-2-1-3-9-20)21-10-5-12-23(16-21)35-22-11-4-7-19(15-22)18-34/h1-17,34H,18H2 UMPNKZORJDFNCA-UHFFFAOYSA-N 35090 biarylether alcohol quinoline, 5c Oxysterols receptor LXR-beta [154-461] Homo sapiens 14 210 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35090&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472982 85753170 ZINC45388570 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62131 OCc1ccc(Oc2cccc(c2)-c2c(cnc3c(cccc23)C(F)(F)F)-c2ccccc2)cc1 InChI=1S/C29H20F3NO2/c30-29(31,32)26-11-5-10-24-27(25(17-33-28(24)26)20-6-2-1-3-7-20)21-8-4-9-23(16-21)35-22-14-12-19(18-34)13-15-22/h1-17,34H,18H2 KKPXMFGSPSGBQW-UHFFFAOYSA-N 35091 biarylether alcohol quinoline, 5d Oxysterols receptor LXR-beta [154-461] Homo sapiens 10 646 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35091&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472983 85753171 ZINC45353497 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62132 OCc1ccc(Oc2cccc(c2)-c2c(cnc3c(Cl)cccc23)-c2ccccc2)cc1 InChI=1S/C28H20ClNO2/c29-26-11-5-10-24-27(25(17-30-28(24)26)20-6-2-1-3-7-20)21-8-4-9-23(16-21)32-22-14-12-19(18-31)13-15-22/h1-17,31H,18H2 YRWXCMJJJAVQPM-UHFFFAOYSA-N 35092 biarylether alcohol quinoline, 5e Oxysterols receptor LXR-beta [154-461] Homo sapiens 8.3 1010 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35092&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472984 85753172 ZINC45366884 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62133 COC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C25H18F3NO3/c1-15-14-29-23-20(10-5-11-21(23)25(26,27)28)22(15)16-6-3-8-18(12-16)32-19-9-4-7-17(13-19)24(30)31-2/h3-14H,1-2H3 IRYOLFKGTYJEPS-UHFFFAOYSA-N 35093 3-methyl quinoline, 8b Oxysterols receptor LXR-beta [154-461] Homo sapiens 435 3400 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35093&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472985 85753173 ZINC45353652 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62134 Cc1cnc2c(cccc2c1-c1cccc(Oc2cccc(CO)c2)c1)C(F)(F)F InChI=1S/C24H18F3NO2/c1-15-13-28-23-20(9-4-10-21(23)24(25,26)27)22(15)17-6-3-8-19(12-17)30-18-7-2-5-16(11-18)14-29/h2-13,29H,14H2,1H3 CQEKMSRTDPXHST-UHFFFAOYSA-N 35094 biarylether alcohol quinoline, 5f Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.1 233 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35094&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16727105 85753174 ZINC45352446 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62135 COC(=O)c1ccc(Oc2cccc(c2)-c2c(C)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C25H18F3NO3/c1-15-14-29-23-20(7-4-8-21(23)25(26,27)28)22(15)17-5-3-6-19(13-17)32-18-11-9-16(10-12-18)24(30)31-2/h3-14H,1-2H3 JAPARGDNOJYVRR-UHFFFAOYSA-N 35095 3-methyl quinoline, 8c Oxysterols receptor LXR-beta [154-461] Homo sapiens >1000 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35095&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472986 85753175 ZINC45352450 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62136 Cc1cnc2c(cccc2c1-c1cccc(Oc2ccc(CO)cc2)c1)C(F)(F)F InChI=1S/C24H18F3NO2/c1-15-13-28-23-20(6-3-7-21(23)24(25,26)27)22(15)17-4-2-5-19(12-17)30-18-10-8-16(14-29)9-11-18/h2-13,29H,14H2,1H3 PPAHYKJOKMIXNQ-UHFFFAOYSA-N 35096 biarylether alcohol quinoline, 5g Oxysterols receptor LXR-beta [154-461] Homo sapiens 31 1370 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35096&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472987 85753176 ZINC45353696 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62137 COC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 InChI=1S/C24H18ClNO3/c1-15-14-26-23-20(10-5-11-21(23)25)22(15)16-6-3-8-18(12-16)29-19-9-4-7-17(13-19)24(27)28-2/h3-14H,1-2H3 DUSQUBZCYLLKHT-UHFFFAOYSA-N 35097 3-methyl quinoline, 8d::BMC171663 Compound 4h Oxysterols receptor LXR-beta [154-461] Homo sapiens 231 1810 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35097&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472988 85753177 ZINC40835965 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62138 Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(CO)c2)c1 InChI=1S/C23H18ClNO2/c1-15-13-25-23-20(9-4-10-21(23)24)22(15)17-6-3-8-19(12-17)27-18-7-2-5-16(11-18)14-26/h2-13,26H,14H2,1H3 GPEAKTSELXSASN-UHFFFAOYSA-N 35098 biarylether alcohol quinoline, 5h Oxysterols receptor LXR-beta [154-461] Homo sapiens 12 938 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35098&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472989 85753178 ZINC45354364 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62139 Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(c2)C(C)(C)O)c1 InChI=1S/C25H22ClNO2/c1-16-15-27-24-21(11-6-12-22(24)26)23(16)17-7-4-9-19(13-17)29-20-10-5-8-18(14-20)25(2,3)28/h4-15,28H,1-3H3 MMQLCGFOEBSWCN-UHFFFAOYSA-N 35099 biarylether alcohol quinoline, 5i Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.5 108 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35099&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472990 85753179 ZINC45388319 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62140 COc1ccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C30H22F3NO2/c1-35-23-13-15-24(16-14-23)36-25-10-5-9-21(18-25)28-22(17-20-7-3-2-4-8-20)19-34-29-26(28)11-6-12-27(29)30(31,32)33/h2-16,18-19H,17H2,1H3 RLNMZAJKGCKXRV-UHFFFAOYSA-N 35100 biarylether methoxy quinoline, 9a Oxysterols receptor LXR-beta [154-461] Homo sapiens 287 612 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35100&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472991 85753180 ZINC45358076 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62141 Oc1ccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C29H20F3NO2/c30-29(31,32)26-11-5-10-25-27(21(18-33-28(25)26)16-19-6-2-1-3-7-19)20-8-4-9-24(17-20)35-23-14-12-22(34)13-15-23/h1-15,17-18,34H,16H2 UKWXHXYFJQOHLJ-UHFFFAOYSA-N 35101 biarylether alcohol quinoline, 9b Oxysterols receptor LXR-beta [154-461] Homo sapiens 28 406 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2009.10.001 10.7270/Q2VH5M54 19853462 aid1799289 Bernotas, RC; Kaufman, DH; Singhaus, RR; Ullrich, J; Unwalla, R; Quinet, E; Nambi, P; Wilhelmsson, A; Goos-Nilsson, A; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35101&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 16718799 85753181 ZINC45349763 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62159 OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 InChI=1S/C32H24F3NO3/c33-32(34,35)28-11-5-10-27-30(25(19-36-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)39-20-23-14-12-22(13-15-23)17-29(37)38/h1-15,18-19H,16-17,20H2,(H,37,38) VXHRQVMQVYQGQG-UHFFFAOYSA-N 20000 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid::CHEMBL214719::JMC496151 Compound 15::WAY-254011 Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.1 93 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=20000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=20000&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search KVB 6S4T 11627859 46519995 CHEMBL214719 C03768 ZINC14972488 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62160 COC(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C31H22F3NO3/c1-37-30(36)22-11-6-13-25(18-22)38-24-12-5-10-21(17-24)28-23(16-20-8-3-2-4-9-20)19-35-29-26(28)14-7-15-27(29)31(32,33)34/h2-15,17-19H,16H2,1H3 LJUJGMRQOWUZEL-UHFFFAOYSA-N 35087 BMC171663 Compound 4a::Benzylquinoline, 8a Oxysterols receptor LXR-beta [154-461] Homo sapiens 53 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35087&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472980 85753167 ZINC40401563 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62161 CCCNC(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C33H27F3N2O2/c1-2-17-37-32(39)24-12-7-14-27(20-24)40-26-13-6-11-23(19-26)30-25(18-22-9-4-3-5-10-22)21-38-31-28(30)15-8-16-29(31)33(34,35)36/h3-16,19-21H,2,17-18H2,1H3,(H,37,39) AJAGFKNPKFWBMC-UHFFFAOYSA-N 35102 biarylether amide quinoline, 4b Oxysterols receptor LXR-beta [154-461] Homo sapiens 8.5 1525 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35102&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472992 85753182 ZINC49867472 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62162 CC(C)NC(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C33H27F3N2O2/c1-21(2)38-32(39)24-12-7-14-27(19-24)40-26-13-6-11-23(18-26)30-25(17-22-9-4-3-5-10-22)20-37-31-28(30)15-8-16-29(31)33(34,35)36/h3-16,18-21H,17H2,1-2H3,(H,38,39) UAHUOJIWTDTEMT-UHFFFAOYSA-N 35103 biarylether amide quinoline, 4c Oxysterols receptor LXR-beta [154-461] Homo sapiens 10 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35103&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472993 85753183 ZINC44359809 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62163 CCN(CC)C(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 InChI=1S/C34H29F3N2O2/c1-3-39(4-2)33(40)25-14-9-16-28(21-25)41-27-15-8-13-24(20-27)31-26(19-23-11-6-5-7-12-23)22-38-32-29(31)17-10-18-30(32)34(35,36)37/h5-18,20-22H,3-4,19H2,1-2H3 GEDMLXRPUQZAAS-UHFFFAOYSA-N 35104 biarylether amide quinoline, 4d Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.8 144 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35104&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472994 85753184 ZINC42835605 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62164 FC(F)(F)c1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(Oc2cccc(c2)C(=O)N2CCCC2)c1 InChI=1S/C34H27F3N2O2/c35-34(36,37)30-16-8-15-29-31(26(22-38-32(29)30)19-23-9-2-1-3-10-23)24-11-6-13-27(20-24)41-28-14-7-12-25(21-28)33(40)39-17-4-5-18-39/h1-3,6-16,20-22H,4-5,17-19H2 QQNXCYFWSCPJOI-UHFFFAOYSA-N 35105 biarylether amide quinoline, 4e Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.6 98 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35105&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472995 85753185 ZINC42805278 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62165 FC(F)(F)c1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(Oc2cccc(c2)C(=O)N2CCCCC2)c1 InChI=1S/C35H29F3N2O2/c36-35(37,38)31-17-9-16-30-32(27(23-39-33(30)31)20-24-10-3-1-4-11-24)25-12-7-14-28(21-25)42-29-15-8-13-26(22-29)34(41)40-18-5-2-6-19-40/h1,3-4,7-17,21-23H,2,5-6,18-20H2 DDVQRICMCZPTNJ-UHFFFAOYSA-N 35106 biarylether amide quinoline, 4f Oxysterols receptor LXR-beta [154-461] Homo sapiens 2.9 170 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35106&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472996 85753186 ZINC44352491 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62166 FC(F)(F)c1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(Oc2cccc(c2)C(=O)N2CCOCC2)c1 InChI=1S/C34H27F3N2O3/c35-34(36,37)30-14-6-13-29-31(26(22-38-32(29)30)19-23-7-2-1-3-8-23)24-9-4-11-27(20-24)42-28-12-5-10-25(21-28)33(40)39-15-17-41-18-16-39/h1-14,20-22H,15-19H2 USWOEXHVBVCJOR-UHFFFAOYSA-N 35107 biarylether amide quinoline, 4g Oxysterols receptor LXR-beta [154-461] Homo sapiens 1.9 138 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35107&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44123769 85753187 ZINC44307886 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62167 COC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 InChI=1S/C24H18ClNO3/c1-15-14-26-23-20(10-5-11-21(23)25)22(15)16-6-3-8-18(12-16)29-19-9-4-7-17(13-19)24(27)28-2/h3-14H,1-2H3 DUSQUBZCYLLKHT-UHFFFAOYSA-N 35097 3-methyl quinoline, 8d::BMC171663 Compound 4h Oxysterols receptor LXR-beta [154-461] Homo sapiens 230 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35097&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472988 85753177 ZINC40835965 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62168 CNC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 InChI=1S/C24H19ClN2O2/c1-15-14-27-23-20(10-5-11-21(23)25)22(15)16-6-3-8-18(12-16)29-19-9-4-7-17(13-19)24(28)26-2/h3-14H,1-2H3,(H,26,28) CGUCJIOARZYDCJ-UHFFFAOYSA-N 35108 biarylether amide quinoline, 4i Oxysterols receptor LXR-beta [154-461] Homo sapiens 9 800 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35108&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472997 85753188 ZINC40866537 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62169 CCNC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 InChI=1S/C25H21ClN2O2/c1-3-27-25(29)18-8-5-10-20(14-18)30-19-9-4-7-17(13-19)23-16(2)15-28-24-21(23)11-6-12-22(24)26/h4-15H,3H2,1-2H3,(H,27,29) DFAPREYFHSKSRA-UHFFFAOYSA-N 35109 biarylether amide quinoline, 4j Oxysterols receptor LXR-beta [154-461] Homo sapiens 20 1272 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35109&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472998 85753189 ZINC40391294 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62170 CCCNC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 InChI=1S/C26H23ClN2O2/c1-3-13-28-26(30)19-8-5-10-21(15-19)31-20-9-4-7-18(14-20)24-17(2)16-29-25-22(24)11-6-12-23(25)27/h4-12,14-16H,3,13H2,1-2H3,(H,28,30) MEBPCMPPKTYENX-UHFFFAOYSA-N 35110 biarylether amide quinoline, 4k Oxysterols receptor LXR-beta [154-461] Homo sapiens 25 1180 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35110&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44472999 85753190 ZINC40393008 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62171 CC(C)NC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 InChI=1S/C26H23ClN2O2/c1-16(2)29-26(30)19-8-5-10-21(14-19)31-20-9-4-7-18(13-20)24-17(3)15-28-25-22(24)11-6-12-23(25)27/h4-16H,1-3H3,(H,29,30) QGOMJEFGXRFUAA-UHFFFAOYSA-N 35111 biarylether amide quinoline, 4l Oxysterols receptor LXR-beta [154-461] Homo sapiens 100 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35111&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44473000 85753191 ZINC40391957 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62172 CCN(CC)C(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 InChI=1S/C27H25ClN2O2/c1-4-30(5-2)27(31)20-10-7-12-22(16-20)32-21-11-6-9-19(15-21)25-18(3)17-29-26-23(25)13-8-14-24(26)28/h6-17H,4-5H2,1-3H3 KWHJGYSZNVMWPZ-UHFFFAOYSA-N 35112 biarylether amide quinoline, 4m Oxysterols receptor LXR-beta [154-461] Homo sapiens 12 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35112&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44473001 85753192 ZINC40865301 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62173 Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(c2)C(=O)N2CCCC2)c1 InChI=1S/C27H23ClN2O2/c1-18-17-29-26-23(11-6-12-24(26)28)25(18)19-7-4-9-21(15-19)32-22-10-5-8-20(16-22)27(31)30-13-2-3-14-30/h4-12,15-17H,2-3,13-14H2,1H3 ITROVDJOIPDCOB-UHFFFAOYSA-N 35113 biarylether amide quinoline, 4n Oxysterols receptor LXR-beta [154-461] Homo sapiens 3 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35113&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44473002 85753193 ZINC40391982 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62174 Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(c2)C(=O)N2CCCCC2)c1 InChI=1S/C28H25ClN2O2/c1-19-18-30-27-24(12-7-13-25(27)29)26(19)20-8-5-10-22(16-20)33-23-11-6-9-21(17-23)28(32)31-14-3-2-4-15-31/h5-13,16-18H,2-4,14-15H2,1H3 PWFODDIPAXPLMJ-UHFFFAOYSA-N 35114 biarylether amide quinoline, 4o Oxysterols receptor LXR-beta [154-461] Homo sapiens 6 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35114&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44473003 85753194 ZINC40860925 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1 62175 Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(c2)C(=O)N2CCOCC2)c1 InChI=1S/C27H23ClN2O3/c1-18-17-29-26-23(9-4-10-24(26)28)25(18)19-5-2-7-21(15-19)33-22-8-3-6-20(16-22)27(31)30-11-13-32-14-12-30/h2-10,15-17H,11-14H2,1H3 IDKRBDPKBAQNEZ-UHFFFAOYSA-N 35115 biarylether amide quinoline, 4p Oxysterols receptor LXR-beta [154-461] Homo sapiens 7 572 7.4 4.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2008.12.048 10.7270/Q2QR4VGV 19162487 aid1799291 Bernotas, RC; Singhaus, RR; Kaufman, DH; Ullrich, J; Fletcher, H; Quinet, E; Nambi, P; Unwalla, R; Wilhelmsson, A; Goos-Nilsson, A; Farnegardh, M; Wrobel, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=35115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2042&target=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=35115&enzyme=Oxysterols+receptor+LXR-beta+%5B154-461%5D&column=ki&startPg=0&Increment=50&submit=Search 44473004 85753195 ZINC40393473 1 MREQCVLSEEQIRKKKIRKQQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVH 1PQ6,1PQ9,1PQC,1UPV,1UPW,3KFC,3L0E,4NQA,4RAK,5JY3,6S4N,6S4T,6S4U,6S5K Oxysterols receptor LXR-beta NR1H2_HUMAN P55055 A8K490 B4DNM6 E7EWA6 Q12970 Q5I0Y1