BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
29515	CCCN(CCC)C(=O)c1cccc(c1)C(=O)N[C@@H](CC(C)C)[C@@H](O)C[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCc1ccccc1	InChI=1S/C36H54N4O5/c1-8-18-40(19-9-2)36(45)29-17-13-16-28(22-29)34(43)38-30(20-24(3)4)31(41)21-26(7)33(42)39-32(25(5)6)35(44)37-23-27-14-11-10-12-15-27/h10-17,22,24-26,30-32,41H,8-9,18-21,23H2,1-7H3,(H,37,44)(H,38,43)(H,39,42)/t26-,30+,31+,32+/m1/s1	LUQWTUMHHVQVET-IOUGBZEOSA-N	16286	3-N-[(1R,3S,4S)-1-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-3-hydroxy-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide::Hydroxyethylene (HE) compound 1::N -[(1S,2S,4R)-5-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]amino}-2-hydroxy-4-methyl-1-(2-methylpropyl)-5-oxopentyl]-N,N-dipropylbenzene-1,3-dicarboxamide	Beta-secretase 1 [22-454]	Homo sapiens	 71						4.5	22.00 C	Curated from the literature by BindingDB	10.1021/jm0509142	10.7270/Q2PV6HM0	16451048	aid1797490		Yang, W; Lu, W; Lu, Y; Zhong, M; Sun, J; Thomas, AE; Wilkinson, JM; Fucini, RV; Lam, M; Randal, M; Shi, XP; Jacobs, JW; McDowell, RS; Gordon, EM; Ballinger, MD	Sunesis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1712&target=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16286&enzyme=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search			11549051	46509501						ZINC10339572	1	TQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST	1FKN,1M4H,1SGZ,1W50,1W51,1XN2,1XN3,1XS7,1YM2,1YM4,2F3E,2F3F,2FDP,2G94,2HIZ,2HM1,2IQG,2OF0,2OHK,2OHL,2OHM,2OHN,2OHP,2OHQ,2OHR,2OHS,2OHT,2OHU,2P4J,2P83,2QK5,2QMD,2QMF,2QMG,2QP8,2QU2,2QU3,2VA5,2VA6,2VA7,2VKM,2WJO,2ZDZ,2ZE1,2ZHR,2ZHS,2ZHT,2ZHU,2ZHV,2ZJN,3CIB,3CIC,3CID,3CKP,3CKR,3DM6,3DUY,3DV1,3DV5,3H0B,3HVG,3HW1,3I25,3IGB,3IN3,3IN4,3IND,3INE,3INF,3INH,3IVH,3IVI,3IXJ,3IXK,3K5C,3K5D,3K5F,3K5G,3KMX,3KMY,3KN0,3KYR,3L38,3L3A,3L58,3L59,3L5B,3L5C,3L5D,3L5E,3L5F,3LHG,3LNK,3LPI,3LPJ,3LPK,3MSJ,3MSK,3MSL,3N4L,3NSH,3OHF,3OHH,3OOZ,3PI5,3QBH,3R1G,3R2F,3RSV,3RSX,3RTH,3RTM,3RTN,3RU1,3RVI,3S2O,3S7L,3S7M,3SKF,3SKG,3TPR,3U6A,3UDH,3UDJ,3UDK,3UDM,3UDN,3UDP,3UDQ,3UDR,3UDY,3UFL,3UQR,3VEU,3VF3,3VG1,3VV6,3VV7,3VV8,3WB4,3WB5,4ACU,4ACX,4AZY,4B00,4B05,4B0Q,4B1C,4B1D,4B1E,4B70,4B72,4B77,4B78,4D83,4D85,4D88,4D89,4D8C,4DH6,4DI2,4DJU,4DJV,4DJW,4DJX,4DJY,4DPF,4DPI,4DUS,4EWO,4EXG,4FM7,4FM8,4FRI,4FRJ,4FRK,4FRS,4FS4,4FSE,4FSL,4GID,4GMI,4H1E,4H3F,4H3G,4H3I,4H3J,4HA5,4HZT,4I0D,4I0E,4I0F,4I0G,4I0H,4I0I,4I0J,4I0Z,4I10,4I11,4I12,4I1C,4JOO,4JP9,4JPC,4JPE,4K8S,4K9H,4KE0,4KE1,4L7G,4L7H,4L7J,4LC7,4LXA,4LXK,4LXM,4N00,4PZW,4PZX,4R5N,4R8Y,4R91,4R92,4R93,4R95,4RCD,4RCE,4RCF,4RRN,4RRO,4RRS,4TRW,4TRY,4TRZ,4WTU,4WY1,4WY6,4X2L,4X7I,4XKX,4XXS,4YBI,4ZSM,4ZSP,4ZSQ,4ZSR,5CLM,5DQC,5ENK,5ENM,5HD0,5HDU,5HDV,5HDX,5HDZ,5HE4,5HE5,5HE7,5HTZ,5HU0,5HU1,5I3V,5I3W,5I3X,5I3Y,5IE1,5KQF,5KR8,5MBW,5MCQ,5MXD,5QCO,5QCP,5QCQ,5QCR,5QCS,5QCT,5QCU,5QCV,5QCW,5QCX,5QCY,5QCZ,5QD0,5QD1,5QD2,5QD3,5QD4,5QD5,5QD6,5QD7,5QD8,5QD9,5QDA,5QDB,5QDC,5QDD,5T1U,5T1W,5TOL,5UYU,5V0N,5YGX,5YGY,6BFD,6BFE,6BFW,6BFX,6C2I,6DHC,6E3Z,6EJ3,6EQM,6FGY,6JSE,6JSF,6JSG,6JSN,6JT3,6JT4,6NV7,6NV9,6NW3,6OD6,6PZ4,6UVP,6UVV,6UVY,6UWP,6UWV,6WNY,7B1E,7B1P,7B1Q,7D2V,7D2X,7D36,7D5A,7DCZ,7F1D,7MYI,7MYR,7MYU,7N66	Beta-secretase 1	BACE1_HUMAN	P56817	A0M8W7 B0YIU9 E9PE65 H7BXJ9 Q9BYB9 Q9BYC0 Q9BYC1 Q9UJT5 Q9ULS1						
29516	CCCN(CCC)C(=O)c1cccc(c1)C(=O)N[C@@H](CC(C)C)[C@@H](N)C[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCc1ccccc1	InChI=1S/C36H55N5O4/c1-8-18-41(19-9-2)36(45)29-17-13-16-28(22-29)34(43)39-31(20-24(3)4)30(37)21-26(7)33(42)40-32(25(5)6)35(44)38-23-27-14-11-10-12-15-27/h10-17,22,24-26,30-32H,8-9,18-21,23,37H2,1-7H3,(H,38,44)(H,39,43)(H,40,42)/t26-,30+,31+,32+/m1/s1	FCHFJDXLCKNCCS-IOUGBZEOSA-N	16287	3-N-[(1R,3S,4S)-3-amino-1-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide::Aminoethylene (AE) compound 2::N -[(1S,2S,4R)-2-amino-5-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]amino}-4-methyl-1-(2-methylpropyl)-5-oxopentyl]-N,N-dipropylbenzene-1,3-dicarboxamide	Beta-secretase 1 [22-454]	Homo sapiens	 120						4.5	22.00 C	Curated from the literature by BindingDB	10.1021/jm0509142	10.7270/Q2PV6HM0	16451048	aid1797490		Yang, W; Lu, W; Lu, Y; Zhong, M; Sun, J; Thomas, AE; Wilkinson, JM; Fucini, RV; Lam, M; Randal, M; Shi, XP; Jacobs, JW; McDowell, RS; Gordon, EM; Ballinger, MD	Sunesis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1712&target=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16287&enzyme=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search			11657376	46516431						ZINC10339576	1	TQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST	1FKN,1M4H,1SGZ,1W50,1W51,1XN2,1XN3,1XS7,1YM2,1YM4,2F3E,2F3F,2FDP,2G94,2HIZ,2HM1,2IQG,2OF0,2OHK,2OHL,2OHM,2OHN,2OHP,2OHQ,2OHR,2OHS,2OHT,2OHU,2P4J,2P83,2QK5,2QMD,2QMF,2QMG,2QP8,2QU2,2QU3,2VA5,2VA6,2VA7,2VKM,2WJO,2ZDZ,2ZE1,2ZHR,2ZHS,2ZHT,2ZHU,2ZHV,2ZJN,3CIB,3CIC,3CID,3CKP,3CKR,3DM6,3DUY,3DV1,3DV5,3H0B,3HVG,3HW1,3I25,3IGB,3IN3,3IN4,3IND,3INE,3INF,3INH,3IVH,3IVI,3IXJ,3IXK,3K5C,3K5D,3K5F,3K5G,3KMX,3KMY,3KN0,3KYR,3L38,3L3A,3L58,3L59,3L5B,3L5C,3L5D,3L5E,3L5F,3LHG,3LNK,3LPI,3LPJ,3LPK,3MSJ,3MSK,3MSL,3N4L,3NSH,3OHF,3OHH,3OOZ,3PI5,3QBH,3R1G,3R2F,3RSV,3RSX,3RTH,3RTM,3RTN,3RU1,3RVI,3S2O,3S7L,3S7M,3SKF,3SKG,3TPR,3U6A,3UDH,3UDJ,3UDK,3UDM,3UDN,3UDP,3UDQ,3UDR,3UDY,3UFL,3UQR,3VEU,3VF3,3VG1,3VV6,3VV7,3VV8,3WB4,3WB5,4ACU,4ACX,4AZY,4B00,4B05,4B0Q,4B1C,4B1D,4B1E,4B70,4B72,4B77,4B78,4D83,4D85,4D88,4D89,4D8C,4DH6,4DI2,4DJU,4DJV,4DJW,4DJX,4DJY,4DPF,4DPI,4DUS,4EWO,4EXG,4FM7,4FM8,4FRI,4FRJ,4FRK,4FRS,4FS4,4FSE,4FSL,4GID,4GMI,4H1E,4H3F,4H3G,4H3I,4H3J,4HA5,4HZT,4I0D,4I0E,4I0F,4I0G,4I0H,4I0I,4I0J,4I0Z,4I10,4I11,4I12,4I1C,4JOO,4JP9,4JPC,4JPE,4K8S,4K9H,4KE0,4KE1,4L7G,4L7H,4L7J,4LC7,4LXA,4LXK,4LXM,4N00,4PZW,4PZX,4R5N,4R8Y,4R91,4R92,4R93,4R95,4RCD,4RCE,4RCF,4RRN,4RRO,4RRS,4TRW,4TRY,4TRZ,4WTU,4WY1,4WY6,4X2L,4X7I,4XKX,4XXS,4YBI,4ZSM,4ZSP,4ZSQ,4ZSR,5CLM,5DQC,5ENK,5ENM,5HD0,5HDU,5HDV,5HDX,5HDZ,5HE4,5HE5,5HE7,5HTZ,5HU0,5HU1,5I3V,5I3W,5I3X,5I3Y,5IE1,5KQF,5KR8,5MBW,5MCQ,5MXD,5QCO,5QCP,5QCQ,5QCR,5QCS,5QCT,5QCU,5QCV,5QCW,5QCX,5QCY,5QCZ,5QD0,5QD1,5QD2,5QD3,5QD4,5QD5,5QD6,5QD7,5QD8,5QD9,5QDA,5QDB,5QDC,5QDD,5T1U,5T1W,5TOL,5UYU,5V0N,5YGX,5YGY,6BFD,6BFE,6BFW,6BFX,6C2I,6DHC,6E3Z,6EJ3,6EQM,6FGY,6JSE,6JSF,6JSG,6JSN,6JT3,6JT4,6NV7,6NV9,6NW3,6OD6,6PZ4,6UVP,6UVV,6UVY,6UWP,6UWV,6WNY,7B1E,7B1P,7B1Q,7D2V,7D2X,7D36,7D5A,7DCZ,7F1D,7MYI,7MYR,7MYU,7N66	Beta-secretase 1	BACE1_HUMAN	P56817	A0M8W7 B0YIU9 E9PE65 H7BXJ9 Q9BYB9 Q9BYC0 Q9BYC1 Q9UJT5 Q9ULS1						
29517	CCCN(CCC)C(=O)c1cccc(c1)C(=O)N[C@@H](CC(C)C)[C@H](N)C[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCc1ccccc1	InChI=1S/C36H55N5O4/c1-8-18-41(19-9-2)36(45)29-17-13-16-28(22-29)34(43)39-31(20-24(3)4)30(37)21-26(7)33(42)40-32(25(5)6)35(44)38-23-27-14-11-10-12-15-27/h10-17,22,24-26,30-32H,8-9,18-21,23,37H2,1-7H3,(H,38,44)(H,39,43)(H,40,42)/t26-,30-,31+,32+/m1/s1	FCHFJDXLCKNCCS-XFDURZHPSA-N	16288	3-N-[(1R,3R,4S)-3-amino-1-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide::Aminoethylene (AE) compound 3::N -[(1S,2R,4R)-2-amino-5-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]amino}-4-methyl-1-(2-methylpropyl)-5-oxopentyl]-N,N-dipropylbenzene-1,3-dicarboxamide	Beta-secretase 1 [22-454]	Homo sapiens	 11300						4.5	22.00 C	Curated from the literature by BindingDB	10.1021/jm0509142	10.7270/Q2PV6HM0	16451048	aid1797490		Yang, W; Lu, W; Lu, Y; Zhong, M; Sun, J; Thomas, AE; Wilkinson, JM; Fucini, RV; Lam, M; Randal, M; Shi, XP; Jacobs, JW; McDowell, RS; Gordon, EM; Ballinger, MD	Sunesis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1712&target=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16288&enzyme=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search			11512869	46516432						ZINC10339578	1	TQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST	1FKN,1M4H,1SGZ,1W50,1W51,1XN2,1XN3,1XS7,1YM2,1YM4,2F3E,2F3F,2FDP,2G94,2HIZ,2HM1,2IQG,2OF0,2OHK,2OHL,2OHM,2OHN,2OHP,2OHQ,2OHR,2OHS,2OHT,2OHU,2P4J,2P83,2QK5,2QMD,2QMF,2QMG,2QP8,2QU2,2QU3,2VA5,2VA6,2VA7,2VKM,2WJO,2ZDZ,2ZE1,2ZHR,2ZHS,2ZHT,2ZHU,2ZHV,2ZJN,3CIB,3CIC,3CID,3CKP,3CKR,3DM6,3DUY,3DV1,3DV5,3H0B,3HVG,3HW1,3I25,3IGB,3IN3,3IN4,3IND,3INE,3INF,3INH,3IVH,3IVI,3IXJ,3IXK,3K5C,3K5D,3K5F,3K5G,3KMX,3KMY,3KN0,3KYR,3L38,3L3A,3L58,3L59,3L5B,3L5C,3L5D,3L5E,3L5F,3LHG,3LNK,3LPI,3LPJ,3LPK,3MSJ,3MSK,3MSL,3N4L,3NSH,3OHF,3OHH,3OOZ,3PI5,3QBH,3R1G,3R2F,3RSV,3RSX,3RTH,3RTM,3RTN,3RU1,3RVI,3S2O,3S7L,3S7M,3SKF,3SKG,3TPR,3U6A,3UDH,3UDJ,3UDK,3UDM,3UDN,3UDP,3UDQ,3UDR,3UDY,3UFL,3UQR,3VEU,3VF3,3VG1,3VV6,3VV7,3VV8,3WB4,3WB5,4ACU,4ACX,4AZY,4B00,4B05,4B0Q,4B1C,4B1D,4B1E,4B70,4B72,4B77,4B78,4D83,4D85,4D88,4D89,4D8C,4DH6,4DI2,4DJU,4DJV,4DJW,4DJX,4DJY,4DPF,4DPI,4DUS,4EWO,4EXG,4FM7,4FM8,4FRI,4FRJ,4FRK,4FRS,4FS4,4FSE,4FSL,4GID,4GMI,4H1E,4H3F,4H3G,4H3I,4H3J,4HA5,4HZT,4I0D,4I0E,4I0F,4I0G,4I0H,4I0I,4I0J,4I0Z,4I10,4I11,4I12,4I1C,4JOO,4JP9,4JPC,4JPE,4K8S,4K9H,4KE0,4KE1,4L7G,4L7H,4L7J,4LC7,4LXA,4LXK,4LXM,4N00,4PZW,4PZX,4R5N,4R8Y,4R91,4R92,4R93,4R95,4RCD,4RCE,4RCF,4RRN,4RRO,4RRS,4TRW,4TRY,4TRZ,4WTU,4WY1,4WY6,4X2L,4X7I,4XKX,4XXS,4YBI,4ZSM,4ZSP,4ZSQ,4ZSR,5CLM,5DQC,5ENK,5ENM,5HD0,5HDU,5HDV,5HDX,5HDZ,5HE4,5HE5,5HE7,5HTZ,5HU0,5HU1,5I3V,5I3W,5I3X,5I3Y,5IE1,5KQF,5KR8,5MBW,5MCQ,5MXD,5QCO,5QCP,5QCQ,5QCR,5QCS,5QCT,5QCU,5QCV,5QCW,5QCX,5QCY,5QCZ,5QD0,5QD1,5QD2,5QD3,5QD4,5QD5,5QD6,5QD7,5QD8,5QD9,5QDA,5QDB,5QDC,5QDD,5T1U,5T1W,5TOL,5UYU,5V0N,5YGX,5YGY,6BFD,6BFE,6BFW,6BFX,6C2I,6DHC,6E3Z,6EJ3,6EQM,6FGY,6JSE,6JSF,6JSG,6JSN,6JT3,6JT4,6NV7,6NV9,6NW3,6OD6,6PZ4,6UVP,6UVV,6UVY,6UWP,6UWV,6WNY,7B1E,7B1P,7B1Q,7D2V,7D2X,7D36,7D5A,7DCZ,7F1D,7MYI,7MYR,7MYU,7N66	Beta-secretase 1	BACE1_HUMAN	P56817	A0M8W7 B0YIU9 E9PE65 H7BXJ9 Q9BYB9 Q9BYC0 Q9BYC1 Q9UJT5 Q9ULS1						
29518	CCCN(CCC)C(=O)c1cccc(c1)C(=O)N[C@@H](CC(C)C)[C@@H](O)C[C@@H](C)C(=O)Nc1ccc(F)cc1	InChI=1S/C30H42FN3O4/c1-6-15-34(16-7-2)30(38)23-10-8-9-22(19-23)29(37)33-26(17-20(3)4)27(35)18-21(5)28(36)32-25-13-11-24(31)12-14-25/h8-14,19-21,26-27,35H,6-7,15-18H2,1-5H3,(H,32,36)(H,33,37)/t21-,26+,27+/m1/s1	AJCHMQHPRWWZRF-AIGMYPEUSA-N	16289	3-N-[(1R,3S,4S)-1-[(4-fluorophenyl)carbamoyl]-3-hydroxy-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide::Hydroxyethylene (HE) compound 4::N -[(1S,2S,4R)-5-[(4-fluorophenyl)amino]-2-hydroxy-4-methyl-1-(2-methylpropyl)-5-oxopentyl]-N,N-dipropylbenzene-1,3-dicarboxamide	Beta-secretase 1 [22-454]	Homo sapiens	 1300						4.5	22.00 C	Curated from the literature by BindingDB	10.1021/jm0509142	10.7270/Q2PV6HM0	16451048	aid1797490		Yang, W; Lu, W; Lu, Y; Zhong, M; Sun, J; Thomas, AE; Wilkinson, JM; Fucini, RV; Lam, M; Randal, M; Shi, XP; Jacobs, JW; McDowell, RS; Gordon, EM; Ballinger, MD	Sunesis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1712&target=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16289&enzyme=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search			11649408	46516532						ZINC10339594	1	TQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST	1FKN,1M4H,1SGZ,1W50,1W51,1XN2,1XN3,1XS7,1YM2,1YM4,2F3E,2F3F,2FDP,2G94,2HIZ,2HM1,2IQG,2OF0,2OHK,2OHL,2OHM,2OHN,2OHP,2OHQ,2OHR,2OHS,2OHT,2OHU,2P4J,2P83,2QK5,2QMD,2QMF,2QMG,2QP8,2QU2,2QU3,2VA5,2VA6,2VA7,2VKM,2WJO,2ZDZ,2ZE1,2ZHR,2ZHS,2ZHT,2ZHU,2ZHV,2ZJN,3CIB,3CIC,3CID,3CKP,3CKR,3DM6,3DUY,3DV1,3DV5,3H0B,3HVG,3HW1,3I25,3IGB,3IN3,3IN4,3IND,3INE,3INF,3INH,3IVH,3IVI,3IXJ,3IXK,3K5C,3K5D,3K5F,3K5G,3KMX,3KMY,3KN0,3KYR,3L38,3L3A,3L58,3L59,3L5B,3L5C,3L5D,3L5E,3L5F,3LHG,3LNK,3LPI,3LPJ,3LPK,3MSJ,3MSK,3MSL,3N4L,3NSH,3OHF,3OHH,3OOZ,3PI5,3QBH,3R1G,3R2F,3RSV,3RSX,3RTH,3RTM,3RTN,3RU1,3RVI,3S2O,3S7L,3S7M,3SKF,3SKG,3TPR,3U6A,3UDH,3UDJ,3UDK,3UDM,3UDN,3UDP,3UDQ,3UDR,3UDY,3UFL,3UQR,3VEU,3VF3,3VG1,3VV6,3VV7,3VV8,3WB4,3WB5,4ACU,4ACX,4AZY,4B00,4B05,4B0Q,4B1C,4B1D,4B1E,4B70,4B72,4B77,4B78,4D83,4D85,4D88,4D89,4D8C,4DH6,4DI2,4DJU,4DJV,4DJW,4DJX,4DJY,4DPF,4DPI,4DUS,4EWO,4EXG,4FM7,4FM8,4FRI,4FRJ,4FRK,4FRS,4FS4,4FSE,4FSL,4GID,4GMI,4H1E,4H3F,4H3G,4H3I,4H3J,4HA5,4HZT,4I0D,4I0E,4I0F,4I0G,4I0H,4I0I,4I0J,4I0Z,4I10,4I11,4I12,4I1C,4JOO,4JP9,4JPC,4JPE,4K8S,4K9H,4KE0,4KE1,4L7G,4L7H,4L7J,4LC7,4LXA,4LXK,4LXM,4N00,4PZW,4PZX,4R5N,4R8Y,4R91,4R92,4R93,4R95,4RCD,4RCE,4RCF,4RRN,4RRO,4RRS,4TRW,4TRY,4TRZ,4WTU,4WY1,4WY6,4X2L,4X7I,4XKX,4XXS,4YBI,4ZSM,4ZSP,4ZSQ,4ZSR,5CLM,5DQC,5ENK,5ENM,5HD0,5HDU,5HDV,5HDX,5HDZ,5HE4,5HE5,5HE7,5HTZ,5HU0,5HU1,5I3V,5I3W,5I3X,5I3Y,5IE1,5KQF,5KR8,5MBW,5MCQ,5MXD,5QCO,5QCP,5QCQ,5QCR,5QCS,5QCT,5QCU,5QCV,5QCW,5QCX,5QCY,5QCZ,5QD0,5QD1,5QD2,5QD3,5QD4,5QD5,5QD6,5QD7,5QD8,5QD9,5QDA,5QDB,5QDC,5QDD,5T1U,5T1W,5TOL,5UYU,5V0N,5YGX,5YGY,6BFD,6BFE,6BFW,6BFX,6C2I,6DHC,6E3Z,6EJ3,6EQM,6FGY,6JSE,6JSF,6JSG,6JSN,6JT3,6JT4,6NV7,6NV9,6NW3,6OD6,6PZ4,6UVP,6UVV,6UVY,6UWP,6UWV,6WNY,7B1E,7B1P,7B1Q,7D2V,7D2X,7D36,7D5A,7DCZ,7F1D,7MYI,7MYR,7MYU,7N66	Beta-secretase 1	BACE1_HUMAN	P56817	A0M8W7 B0YIU9 E9PE65 H7BXJ9 Q9BYB9 Q9BYC0 Q9BYC1 Q9UJT5 Q9ULS1						
29519	CCCN(CCC)C(=O)c1cccc(c1)C(=O)N[C@@H](CC(C)C)[C@@H](N)C[C@@H](C)C(=O)Nc1ccc(F)cc1	InChI=1S/C30H43FN4O3/c1-6-15-35(16-7-2)30(38)23-10-8-9-22(19-23)29(37)34-27(17-20(3)4)26(32)18-21(5)28(36)33-25-13-11-24(31)12-14-25/h8-14,19-21,26-27H,6-7,15-18,32H2,1-5H3,(H,33,36)(H,34,37)/t21-,26+,27+/m1/s1	VMVZSPLWCGEHMQ-AIGMYPEUSA-N	16290	3-N-[(1R,3S,4S)-3-amino-1-[(4-fluorophenyl)carbamoyl]-1,6-dimethylheptan-4-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide::Aminoethylene (AE) compound 5::N -[(1S,2S,4R)-2-amino-5-[(4-fluorophenyl)amino]-4-methyl-1-(2-methylpropyl)-5-oxopentyl]-N,N-dipropylbenzene-1,3-dicarboxamide	Beta-secretase 1 [22-454]	Homo sapiens	 3000						4.5	22.00 C	Curated from the literature by BindingDB	10.1021/jm0509142	10.7270/Q2PV6HM0	16451048	aid1797490		Yang, W; Lu, W; Lu, Y; Zhong, M; Sun, J; Thomas, AE; Wilkinson, JM; Fucini, RV; Lam, M; Randal, M; Shi, XP; Jacobs, JW; McDowell, RS; Gordon, EM; Ballinger, MD	Sunesis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1712&target=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16290&enzyme=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search			11512035	46516533						ZINC10339598	1	TQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST	1FKN,1M4H,1SGZ,1W50,1W51,1XN2,1XN3,1XS7,1YM2,1YM4,2F3E,2F3F,2FDP,2G94,2HIZ,2HM1,2IQG,2OF0,2OHK,2OHL,2OHM,2OHN,2OHP,2OHQ,2OHR,2OHS,2OHT,2OHU,2P4J,2P83,2QK5,2QMD,2QMF,2QMG,2QP8,2QU2,2QU3,2VA5,2VA6,2VA7,2VKM,2WJO,2ZDZ,2ZE1,2ZHR,2ZHS,2ZHT,2ZHU,2ZHV,2ZJN,3CIB,3CIC,3CID,3CKP,3CKR,3DM6,3DUY,3DV1,3DV5,3H0B,3HVG,3HW1,3I25,3IGB,3IN3,3IN4,3IND,3INE,3INF,3INH,3IVH,3IVI,3IXJ,3IXK,3K5C,3K5D,3K5F,3K5G,3KMX,3KMY,3KN0,3KYR,3L38,3L3A,3L58,3L59,3L5B,3L5C,3L5D,3L5E,3L5F,3LHG,3LNK,3LPI,3LPJ,3LPK,3MSJ,3MSK,3MSL,3N4L,3NSH,3OHF,3OHH,3OOZ,3PI5,3QBH,3R1G,3R2F,3RSV,3RSX,3RTH,3RTM,3RTN,3RU1,3RVI,3S2O,3S7L,3S7M,3SKF,3SKG,3TPR,3U6A,3UDH,3UDJ,3UDK,3UDM,3UDN,3UDP,3UDQ,3UDR,3UDY,3UFL,3UQR,3VEU,3VF3,3VG1,3VV6,3VV7,3VV8,3WB4,3WB5,4ACU,4ACX,4AZY,4B00,4B05,4B0Q,4B1C,4B1D,4B1E,4B70,4B72,4B77,4B78,4D83,4D85,4D88,4D89,4D8C,4DH6,4DI2,4DJU,4DJV,4DJW,4DJX,4DJY,4DPF,4DPI,4DUS,4EWO,4EXG,4FM7,4FM8,4FRI,4FRJ,4FRK,4FRS,4FS4,4FSE,4FSL,4GID,4GMI,4H1E,4H3F,4H3G,4H3I,4H3J,4HA5,4HZT,4I0D,4I0E,4I0F,4I0G,4I0H,4I0I,4I0J,4I0Z,4I10,4I11,4I12,4I1C,4JOO,4JP9,4JPC,4JPE,4K8S,4K9H,4KE0,4KE1,4L7G,4L7H,4L7J,4LC7,4LXA,4LXK,4LXM,4N00,4PZW,4PZX,4R5N,4R8Y,4R91,4R92,4R93,4R95,4RCD,4RCE,4RCF,4RRN,4RRO,4RRS,4TRW,4TRY,4TRZ,4WTU,4WY1,4WY6,4X2L,4X7I,4XKX,4XXS,4YBI,4ZSM,4ZSP,4ZSQ,4ZSR,5CLM,5DQC,5ENK,5ENM,5HD0,5HDU,5HDV,5HDX,5HDZ,5HE4,5HE5,5HE7,5HTZ,5HU0,5HU1,5I3V,5I3W,5I3X,5I3Y,5IE1,5KQF,5KR8,5MBW,5MCQ,5MXD,5QCO,5QCP,5QCQ,5QCR,5QCS,5QCT,5QCU,5QCV,5QCW,5QCX,5QCY,5QCZ,5QD0,5QD1,5QD2,5QD3,5QD4,5QD5,5QD6,5QD7,5QD8,5QD9,5QDA,5QDB,5QDC,5QDD,5T1U,5T1W,5TOL,5UYU,5V0N,5YGX,5YGY,6BFD,6BFE,6BFW,6BFX,6C2I,6DHC,6E3Z,6EJ3,6EQM,6FGY,6JSE,6JSF,6JSG,6JSN,6JT3,6JT4,6NV7,6NV9,6NW3,6OD6,6PZ4,6UVP,6UVV,6UVY,6UWP,6UWV,6WNY,7B1E,7B1P,7B1Q,7D2V,7D2X,7D36,7D5A,7DCZ,7F1D,7MYI,7MYR,7MYU,7N66	Beta-secretase 1	BACE1_HUMAN	P56817	A0M8W7 B0YIU9 E9PE65 H7BXJ9 Q9BYB9 Q9BYC0 Q9BYC1 Q9UJT5 Q9ULS1						
29520	CCCN(CCC)C(=O)c1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](N)C[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)NCc1ccccc1	InChI=1S/C39H53N5O4/c1-6-21-44(22-7-2)39(48)32-20-14-19-31(25-32)37(46)42-34(24-29-15-10-8-11-16-29)33(40)23-28(5)36(45)43-35(27(3)4)38(47)41-26-30-17-12-9-13-18-30/h8-20,25,27-28,33-35H,6-7,21-24,26,40H2,1-5H3,(H,41,47)(H,42,46)(H,43,45)/t28-,33+,34+,35+/m1/s1	CFGDZHHUKZKWPM-FXLHSRMHSA-N	16291	3-N-[(2S,3S,5R)-3-amino-5-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]carbamoyl}-5-methyl-1-phenylpentan-2-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide::Aminoethylene (AE) compound 6::N -[(1S,2S,4R)-2-amino-1-benzyl-5-{[(1S)-1-(benzylcarbamoyl)-2-methylpropyl]amino}-4-methyl-5-oxopentyl]-N,N-dipropylbenzene-1,3-dicarboxamide	Beta-secretase 1 [22-454]	Homo sapiens	 33						4.5	22.00 C	Curated from the literature by BindingDB	10.1021/jm0509142	10.7270/Q2PV6HM0	16451048	aid1797490		Yang, W; Lu, W; Lu, Y; Zhong, M; Sun, J; Thomas, AE; Wilkinson, JM; Fucini, RV; Lam, M; Randal, M; Shi, XP; Jacobs, JW; McDowell, RS; Gordon, EM; Ballinger, MD	Sunesis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1712&target=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16291&enzyme=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search			11621627	46516502						ZINC28566943	1	TQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST	1FKN,1M4H,1SGZ,1W50,1W51,1XN2,1XN3,1XS7,1YM2,1YM4,2F3E,2F3F,2FDP,2G94,2HIZ,2HM1,2IQG,2OF0,2OHK,2OHL,2OHM,2OHN,2OHP,2OHQ,2OHR,2OHS,2OHT,2OHU,2P4J,2P83,2QK5,2QMD,2QMF,2QMG,2QP8,2QU2,2QU3,2VA5,2VA6,2VA7,2VKM,2WJO,2ZDZ,2ZE1,2ZHR,2ZHS,2ZHT,2ZHU,2ZHV,2ZJN,3CIB,3CIC,3CID,3CKP,3CKR,3DM6,3DUY,3DV1,3DV5,3H0B,3HVG,3HW1,3I25,3IGB,3IN3,3IN4,3IND,3INE,3INF,3INH,3IVH,3IVI,3IXJ,3IXK,3K5C,3K5D,3K5F,3K5G,3KMX,3KMY,3KN0,3KYR,3L38,3L3A,3L58,3L59,3L5B,3L5C,3L5D,3L5E,3L5F,3LHG,3LNK,3LPI,3LPJ,3LPK,3MSJ,3MSK,3MSL,3N4L,3NSH,3OHF,3OHH,3OOZ,3PI5,3QBH,3R1G,3R2F,3RSV,3RSX,3RTH,3RTM,3RTN,3RU1,3RVI,3S2O,3S7L,3S7M,3SKF,3SKG,3TPR,3U6A,3UDH,3UDJ,3UDK,3UDM,3UDN,3UDP,3UDQ,3UDR,3UDY,3UFL,3UQR,3VEU,3VF3,3VG1,3VV6,3VV7,3VV8,3WB4,3WB5,4ACU,4ACX,4AZY,4B00,4B05,4B0Q,4B1C,4B1D,4B1E,4B70,4B72,4B77,4B78,4D83,4D85,4D88,4D89,4D8C,4DH6,4DI2,4DJU,4DJV,4DJW,4DJX,4DJY,4DPF,4DPI,4DUS,4EWO,4EXG,4FM7,4FM8,4FRI,4FRJ,4FRK,4FRS,4FS4,4FSE,4FSL,4GID,4GMI,4H1E,4H3F,4H3G,4H3I,4H3J,4HA5,4HZT,4I0D,4I0E,4I0F,4I0G,4I0H,4I0I,4I0J,4I0Z,4I10,4I11,4I12,4I1C,4JOO,4JP9,4JPC,4JPE,4K8S,4K9H,4KE0,4KE1,4L7G,4L7H,4L7J,4LC7,4LXA,4LXK,4LXM,4N00,4PZW,4PZX,4R5N,4R8Y,4R91,4R92,4R93,4R95,4RCD,4RCE,4RCF,4RRN,4RRO,4RRS,4TRW,4TRY,4TRZ,4WTU,4WY1,4WY6,4X2L,4X7I,4XKX,4XXS,4YBI,4ZSM,4ZSP,4ZSQ,4ZSR,5CLM,5DQC,5ENK,5ENM,5HD0,5HDU,5HDV,5HDX,5HDZ,5HE4,5HE5,5HE7,5HTZ,5HU0,5HU1,5I3V,5I3W,5I3X,5I3Y,5IE1,5KQF,5KR8,5MBW,5MCQ,5MXD,5QCO,5QCP,5QCQ,5QCR,5QCS,5QCT,5QCU,5QCV,5QCW,5QCX,5QCY,5QCZ,5QD0,5QD1,5QD2,5QD3,5QD4,5QD5,5QD6,5QD7,5QD8,5QD9,5QDA,5QDB,5QDC,5QDD,5T1U,5T1W,5TOL,5UYU,5V0N,5YGX,5YGY,6BFD,6BFE,6BFW,6BFX,6C2I,6DHC,6E3Z,6EJ3,6EQM,6FGY,6JSE,6JSF,6JSG,6JSN,6JT3,6JT4,6NV7,6NV9,6NW3,6OD6,6PZ4,6UVP,6UVV,6UVY,6UWP,6UWV,6WNY,7B1E,7B1P,7B1Q,7D2V,7D2X,7D36,7D5A,7DCZ,7F1D,7MYI,7MYR,7MYU,7N66	Beta-secretase 1	BACE1_HUMAN	P56817	A0M8W7 B0YIU9 E9PE65 H7BXJ9 Q9BYB9 Q9BYC0 Q9BYC1 Q9UJT5 Q9ULS1						
29521	CCCN(CCC)C(=O)c1cccc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](N)C[C@@H](C)C(=O)Nc1ccc(F)cc1	InChI=1S/C33H41FN4O3/c1-4-18-38(19-5-2)33(41)26-13-9-12-25(22-26)32(40)37-30(21-24-10-7-6-8-11-24)29(35)20-23(3)31(39)36-28-16-14-27(34)15-17-28/h6-17,22-23,29-30H,4-5,18-21,35H2,1-3H3,(H,36,39)(H,37,40)/t23-,29+,30+/m1/s1	PZHFCAIXAVDQAK-STQWGSIPSA-N	16292	3-N-[(2S,3S,5R)-3-amino-5-[(4-fluorophenyl)carbamoyl]-5-methyl-1-phenylpentan-2-yl]-1-N,1-N-dipropylbenzene-1,3-dicarboxamide::Aminoethylene (AE) compound 7::N -{(1S,2S,4R)-2-amino-1-benzyl-5-[(4-fluorophenyl)amino]-4-methyl-5-oxopentyl}-N,N-dipropylbenzene-1,3-dicarboxamide	Beta-secretase 1 [22-454]	Homo sapiens	 26						4.5	22.00 C	Curated from the literature by BindingDB	10.1021/jm0509142	10.7270/Q2PV6HM0	16451048	aid1797490		Yang, W; Lu, W; Lu, Y; Zhong, M; Sun, J; Thomas, AE; Wilkinson, JM; Fucini, RV; Lam, M; Randal, M; Shi, XP; Jacobs, JW; McDowell, RS; Gordon, EM; Ballinger, MD	Sunesis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=1712&target=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16292&enzyme=Beta-secretase+1+%5B22-454%5D&column=ki&startPg=0&Increment=50&submit=Search	FRP	2FDP	5494423	46516535						ZINC10339558	1	TQHGIRLPLRSGLGGAPLGLRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDEST	1FKN,1M4H,1SGZ,1W50,1W51,1XN2,1XN3,1XS7,1YM2,1YM4,2F3E,2F3F,2FDP,2G94,2HIZ,2HM1,2IQG,2OF0,2OHK,2OHL,2OHM,2OHN,2OHP,2OHQ,2OHR,2OHS,2OHT,2OHU,2P4J,2P83,2QK5,2QMD,2QMF,2QMG,2QP8,2QU2,2QU3,2VA5,2VA6,2VA7,2VKM,2WJO,2ZDZ,2ZE1,2ZHR,2ZHS,2ZHT,2ZHU,2ZHV,2ZJN,3CIB,3CIC,3CID,3CKP,3CKR,3DM6,3DUY,3DV1,3DV5,3H0B,3HVG,3HW1,3I25,3IGB,3IN3,3IN4,3IND,3INE,3INF,3INH,3IVH,3IVI,3IXJ,3IXK,3K5C,3K5D,3K5F,3K5G,3KMX,3KMY,3KN0,3KYR,3L38,3L3A,3L58,3L59,3L5B,3L5C,3L5D,3L5E,3L5F,3LHG,3LNK,3LPI,3LPJ,3LPK,3MSJ,3MSK,3MSL,3N4L,3NSH,3OHF,3OHH,3OOZ,3PI5,3QBH,3R1G,3R2F,3RSV,3RSX,3RTH,3RTM,3RTN,3RU1,3RVI,3S2O,3S7L,3S7M,3SKF,3SKG,3TPR,3U6A,3UDH,3UDJ,3UDK,3UDM,3UDN,3UDP,3UDQ,3UDR,3UDY,3UFL,3UQR,3VEU,3VF3,3VG1,3VV6,3VV7,3VV8,3WB4,3WB5,4ACU,4ACX,4AZY,4B00,4B05,4B0Q,4B1C,4B1D,4B1E,4B70,4B72,4B77,4B78,4D83,4D85,4D88,4D89,4D8C,4DH6,4DI2,4DJU,4DJV,4DJW,4DJX,4DJY,4DPF,4DPI,4DUS,4EWO,4EXG,4FM7,4FM8,4FRI,4FRJ,4FRK,4FRS,4FS4,4FSE,4FSL,4GID,4GMI,4H1E,4H3F,4H3G,4H3I,4H3J,4HA5,4HZT,4I0D,4I0E,4I0F,4I0G,4I0H,4I0I,4I0J,4I0Z,4I10,4I11,4I12,4I1C,4JOO,4JP9,4JPC,4JPE,4K8S,4K9H,4KE0,4KE1,4L7G,4L7H,4L7J,4LC7,4LXA,4LXK,4LXM,4N00,4PZW,4PZX,4R5N,4R8Y,4R91,4R92,4R93,4R95,4RCD,4RCE,4RCF,4RRN,4RRO,4RRS,4TRW,4TRY,4TRZ,4WTU,4WY1,4WY6,4X2L,4X7I,4XKX,4XXS,4YBI,4ZSM,4ZSP,4ZSQ,4ZSR,5CLM,5DQC,5ENK,5ENM,5HD0,5HDU,5HDV,5HDX,5HDZ,5HE4,5HE5,5HE7,5HTZ,5HU0,5HU1,5I3V,5I3W,5I3X,5I3Y,5IE1,5KQF,5KR8,5MBW,5MCQ,5MXD,5QCO,5QCP,5QCQ,5QCR,5QCS,5QCT,5QCU,5QCV,5QCW,5QCX,5QCY,5QCZ,5QD0,5QD1,5QD2,5QD3,5QD4,5QD5,5QD6,5QD7,5QD8,5QD9,5QDA,5QDB,5QDC,5QDD,5T1U,5T1W,5TOL,5UYU,5V0N,5YGX,5YGY,6BFD,6BFE,6BFW,6BFX,6C2I,6DHC,6E3Z,6EJ3,6EQM,6FGY,6JSE,6JSF,6JSG,6JSN,6JT3,6JT4,6NV7,6NV9,6NW3,6OD6,6PZ4,6UVP,6UVV,6UVY,6UWP,6UWV,6WNY,7B1E,7B1P,7B1Q,7D2V,7D2X,7D36,7D5A,7DCZ,7F1D,7MYI,7MYR,7MYU,7N66	Beta-secretase 1	BACE1_HUMAN	P56817	A0M8W7 B0YIU9 E9PE65 H7BXJ9 Q9BYB9 Q9BYC0 Q9BYC1 Q9UJT5 Q9ULS1