BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
325920	CCOC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Nc2cccc(c2)C#N)cc1	InChI=1S/C28H26N6O2S/c1-5-36-24(35)14-23-27-33-32-18(4)34(27)28-25(16(2)17(3)37-28)26(31-23)20-9-11-21(12-10-20)30-22-8-6-7-19(13-22)15-29/h6-13,23,30H,5,14H2,1-4H3/t23-/m0/s1	QSZLUBPLEBWTKU-QHCPKHFHSA-N	179275	US9125915, compound 2	Bromodomain-containing protein 4/Histone H4			 121.2						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179275&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			118987505	313064547							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325921	CCOC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Nc2cccnc2)cc1	InChI=1S/C26H26N6O2S/c1-5-34-22(33)13-21-25-31-30-17(4)32(25)26-23(15(2)16(3)35-26)24(29-21)18-8-10-19(11-9-18)28-20-7-6-12-27-14-20/h6-12,14,21,28H,5,13H2,1-4H3/t21-/m0/s1	QTHRZMXZOREJPN-NRFANRHFSA-N	179280	US9125915, compound 3	Bromodomain-containing protein 4/Histone H4			 54.9						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179280&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			59569000	313064551							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325922	COC(=O)C[C@@H]1N=C(c2c(C)c(CO)sc2-n2c(C)nnc12)c1ccc(Nc2c(F)cc(F)cc2F)cc1	InChI=1S/C26H22F3N5O3S/c1-12-20(11-35)38-26-22(12)23(31-19(10-21(36)37-3)25-33-32-13(2)34(25)26)14-4-6-16(7-5-14)30-24-17(28)8-15(27)9-18(24)29/h4-9,19,30,35H,10-11H2,1-3H3/t19-/m0/s1	HBYLVKAXSCOSII-IBGZPJMESA-N	179281	US9125915, compound 4	Bromodomain-containing protein 4/Histone H4			 77.2						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179281&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			59569001	313064552							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325923	COC(=O)C[C@@H]1N=C(c2c(C)c(Cl)sc2-n2c(C)nnc12)c1ccc(Cl)cc1	InChI=1S/C19H16Cl2N4O2S/c1-9-15-16(11-4-6-12(20)7-5-11)22-13(8-14(26)27-3)18-24-23-10(2)25(18)19(15)28-17(9)21/h4-7,13H,8H2,1-3H3/t13-/m0/s1	BOAAVUCORGTJIT-ZDUSSCGKSA-N	179282	US9125915, compound 5	Bromodomain-containing protein 4/Histone H4			 54.2						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179282&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			59569005	313064553							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325924	COC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1	InChI=1S/C20H19ClN4O2S/c1-10-11(2)28-20-17(10)18(13-5-7-14(21)8-6-13)22-15(9-16(26)27-4)19-24-23-12(3)25(19)20/h5-8,15H,9H2,1-4H3/t15-/m0/s1	GGRCIHACOIMRKY-HNNXBMFYSA-N	179283	US9125915, compound 6	Bromodomain-containing protein 4/Histone H4			 18.2						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179283&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	0S6	6DUV,4F3I,5UEU	59190723	313064554							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325925	COC(=O)C[C@@H]1N=C(c2c(C)c(CO)sc2-n2c(C)nnc12)c1ccc(cc1)-c1ccc(OC)cc1	InChI=1S/C27H26N4O4S/c1-15-22(14-32)36-27-24(15)25(28-21(13-23(33)35-4)26-30-29-16(2)31(26)27)19-7-5-17(6-8-19)18-9-11-20(34-3)12-10-18/h5-12,21,32H,13-14H2,1-4H3/t21-/m0/s1	RILNLUBNEAZMHA-NRFANRHFSA-N	179276	US9125915, compound 7	Bromodomain-containing protein 4/Histone H4			 113						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179276	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179276&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			15978961	313064548							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325926	COC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Nc2ccccc2)cc1	InChI=1S/C26H25N5O2S/c1-15-16(2)34-26-23(15)24(18-10-12-20(13-11-18)27-19-8-6-5-7-9-19)28-21(14-22(32)33-4)25-30-29-17(3)31(25)26/h5-13,21,27H,14H2,1-4H3/t21-/m0/s1	OOWCQDANWVVOPI-NRFANRHFSA-N	179284	US9125915, compound 8	Bromodomain-containing protein 4/Histone H4			 123.5						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179284&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			15978963	313064555							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325927	COC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(NCc2ccccc2)cc1	InChI=1S/C27H27N5O2S/c1-16-17(2)35-27-24(16)25(29-22(14-23(33)34-4)26-31-30-18(3)32(26)27)20-10-12-21(13-11-20)28-15-19-8-6-5-7-9-19/h5-13,22,28H,14-15H2,1-4H3/t22-/m0/s1	FOKWGPXYCGQWPL-QFIPXVFZSA-N	179285	US9125915, compound 9	Bromodomain-containing protein 4/Histone H4			 73.6						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179285&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			15978964	313064556							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325928	COC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(NC(=O)CCc2ccccc2)cc1	InChI=1S/C29H29N5O3S/c1-17-18(2)38-29-26(17)27(31-23(16-25(36)37-4)28-33-32-19(3)34(28)29)21-11-13-22(14-12-21)30-24(35)15-10-20-8-6-5-7-9-20/h5-9,11-14,23H,10,15-16H2,1-4H3,(H,30,35)/t23-/m0/s1	OZHGOXVBHNGBBM-QHCPKHFHSA-N	179277	US9125915, compound 10	Bromodomain-containing protein 4/Histone H4			 47.1						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179277&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			11973737	313064549							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325929	CCOC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(cc1)N(C)c1ccc(F)cc1	InChI=1S/C28H28FN5O2S/c1-6-36-24(35)15-23-27-32-31-18(4)34(27)28-25(16(2)17(3)37-28)26(30-23)19-7-11-21(12-8-19)33(5)22-13-9-20(29)10-14-22/h7-14,23H,6,15H2,1-5H3/t23-/m0/s1	ACUDCGWCFBKYKV-QHCPKHFHSA-N	179286	US9125915, compound 11	Bromodomain-containing protein 4/Histone H4			 225.3						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179286&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			15978960	313064557							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325930	Cc1nnc2C(CC(=O)Nc3cccnc3)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1	InChI=1S/C24H21ClN6OS/c1-13-14(2)33-24-21(13)22(16-6-8-17(25)9-7-16)28-19(23-30-29-15(3)31(23)24)11-20(32)27-18-5-4-10-26-12-18/h4-10,12,19H,11H2,1-3H3,(H,27,32)	FKUMGWIMVNELEN-UHFFFAOYSA-N	179287	US9125915, compound 12	Bromodomain-containing protein 4/Histone H4			 107.8						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179287&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			19704996	313064558							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325931	CNC(=O)CC1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1	InChI=1S/C20H20ClN5OS/c1-10-11(2)28-20-17(10)18(13-5-7-14(21)8-6-13)23-15(9-16(27)22-4)19-25-24-12(3)26(19)20/h5-8,15H,9H2,1-4H3,(H,22,27)	KCVBJYCYUYBMEV-UHFFFAOYSA-N	179288	US9125915, compound 13	Bromodomain-containing protein 4/Histone H4			 17.3						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179288&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			19704933	313064559							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325932	Cc1sc-2c(c1C)C(=NC(CC(=O)NCCO)c1nnc(C)n-21)c1ccc(Cl)cc1	InChI=1S/C21H22ClN5O2S/c1-11-12(2)30-21-18(11)19(14-4-6-15(22)7-5-14)24-16(10-17(29)23-8-9-28)20-26-25-13(3)27(20)21/h4-7,16,28H,8-10H2,1-3H3,(H,23,29)	DHJBCEVAMQVGRX-UHFFFAOYSA-N	179289	US9125915, compound 14	Bromodomain-containing protein 4/Histone H4			 21						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179289&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			19704974	313064560					C04080		2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325933	Cc1sc-2c(c1C)C(=NC(CC(=O)Nc1ccc(N)cc1)c1nnc(C)n-21)c1ccc(Cl)cc1	InChI=1S/C25H23ClN6OS/c1-13-14(2)34-25-22(13)23(16-4-6-17(26)7-5-16)29-20(24-31-30-15(3)32(24)25)12-21(33)28-19-10-8-18(27)9-11-19/h4-11,20H,12,27H2,1-3H3,(H,28,33)	AJAPVWZEHWUYBM-UHFFFAOYSA-N	179290	US9125915, compound 15	Bromodomain-containing protein 4/Histone H4			 119.8						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179290&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			19704928	313064561							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325934	COc1ccc(NC(=O)C[C@@H]2N=C(c3c(C)c(C)sc3-n3c(C)nnc23)c2ccc(Cl)cc2)cn1	InChI=1S/C25H23ClN6O2S/c1-13-14(2)35-25-22(13)23(16-5-7-17(26)8-6-16)29-19(24-31-30-15(3)32(24)25)11-20(33)28-18-9-10-21(34-4)27-12-18/h5-10,12,19H,11H2,1-4H3,(H,28,33)/t19-/m0/s1	OKRJFYDTVGCNMM-IBGZPJMESA-N	179291	US9125915, compound 16	Bromodomain-containing protein 4/Histone H4			 116.4						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179291&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			59569003	313064562							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325935	CONC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1	InChI=1S/C20H20ClN5O2S/c1-10-11(2)29-20-17(10)18(13-5-7-14(21)8-6-13)22-15(9-16(27)25-28-4)19-24-23-12(3)26(19)20/h5-8,15H,9H2,1-4H3,(H,25,27)/t15-/m0/s1	CEFSBNHGMUZWQG-HNNXBMFYSA-N	179292	US9125915, compound 17	Bromodomain-containing protein 4/Histone H4			 12.8						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179292&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			59569002	313064563							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7						
325936	COc1ncccc1NC(=O)C[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1	InChI=1S/C25H23ClN6O2S/c1-13-14(2)35-25-21(13)22(16-7-9-17(26)10-8-16)29-19(23-31-30-15(3)32(23)25)12-20(33)28-18-6-5-11-27-24(18)34-4/h5-11,19H,12H2,1-4H3,(H,28,33)/t19-/m0/s1	MGYLEFLOKAYSBT-IBGZPJMESA-N	179279	US9125915, compound 18	Bromodomain-containing protein 4/Histone H4			 146.8						25.00 C	US Patent		10.7270/Q26972BJ		aid1801583	US9125915	Miyoshi, S; Ooike, S; Iwata, K; Hikawa, H; Sugahara, K	Mitsubishi Tanabe Pharma Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=179279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=50001694&target=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=179279&enzyme=Bromodomain-containing+protein+4%2FHistone+H4&column=ki&startPg=0&Increment=50&submit=Search			59569004	313064550							2	MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF	2I8N,2JNS,2LSP,2MJV,2N3K,2NCZ,2ND0,2ND1,2OUO,2YEM,4DON,4HXK,4HXL,4HXM,4HXN,4HXO,4HXP,4HXR,4HXS,4KV4,4LYS,4Z93,5D24,5D25,5D3H,5D3J,5D3N,5D3S,5H21,5HQ7,5I80,5I88,5JWM,5KU3,5T35,5U28,5U2C,5UEO,5UEP,5UEQ,5UER,5UES,5UET,5UEU,5UEV,5UEX,5UEY,5UEZ,5UF0,5UOO,5UVS,5UVT,5UVU,5UVV,5UVW,5UVX,5UVY,5UVZ,5VZS,5W55,5WA5,5WUU,5XHY,5XI2,5XI3,5XI4,5Y1Y,5Z5T,5Z5U,5Z5V,6AJV,6AJW,6AJX,6AJY,6AJZ,6BNH,6C7Q,6CD4,6CJ2,6CKR,6CKS,6DJC,6DNE,6DUV,6FFD,6IN1,6JI3,6JI4,6JI5,6JJ3,6JJ5,6JJ6,6JJB,6KO2,6LG4,6LG5,6LG6,6LG7,6LG8,6LG9,6LIH,6LIM,6MNL,6P05,6SIS,6VIW,6VIX,6VIZ,6WW8,6X7D,7AQT,7C2Z,7C6P,7EHW,7EHY,7EIG,7EIK,7EIL,7FH2,7JKW,7JKX,7JKY,7JKZ,7KO0,7LA9,7REK,7RUH,7RUI,7TV0,7USJ,7USK,7ZNT,8BDT,8BDX,8G46,8GPZ,8GQ0	Bromodomain-containing protein 4	BRD4_HUMAN	O60885	O60433 Q4G0X8 Q86YS8 Q96PD3							MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG	1EQZ,1F66,1HIO,1HQ3,1KX3,1KX4,1KX5,1M18,1M19,1M1A,1P34,1P3A,1P3B,1P3F,1P3G,1P3I,1P3K,1P3L,1P3M,1P3O,1P3P,1S32,1TZY,1U35,1ZBB,1ZLA,2ARO,2CV5,2F8N,2FJ7,2HUE,2IO5,2NQB,2NZD,2PYO,3A6N,3AFA,3AN2,3AV1,3AV2,3AYW,3AZE,3AZF,3AZG,3AZH,3B6F,3B6G,3C1B,3C1C,3C9K,3KUY,3KWQ,3KXB,3LEL,3LJA,3LZ0,3LZ1,3MGP,3MGQ,3MGR,3MGS,3MNN,3MVD,3NQJ,3NQU,3O62,3R45,3REH,3REI,3REJ,3REK,3REL,3TU4,3UT9,3UTA,3UTB,3W96,3W97,3W98,3W99,3WA9,3WAA,3WKJ,3WTP,3X1S,3X1T,3X1U,3X1V,4H9N,4H9O,4H9P,4H9Q,4H9R,4H9S,4HGA,4J8U,4J8V,4J8W,4J8X,4KGC,4LD9,4PSX,4QLC,4R8P,4WU8,4WU9,4X23,4XUJ,4XZQ,4YM5,4YM6,4YS3,4Z2M,4Z5T,4Z66,4ZBJ,4ZUX,5AV5,5AV6,5AV8,5AV9,5AVB,5AVC,5AY8,5B0Y,5B0Z,5B1L,5B1M,5B24,5B2I,5B2J,5B31,5B32,5B33,5BNV,5BNX,5BO0,5BS7,5BSA,5C3I,5CP6,5CPI,5CPJ,5CPK,5DNM,5DNN,5E5A,5GSE,5GSU,5GT0,5GT3,5GTC,5GXQ,5HQ2,5JA4,5JRG,5KDM,5KGF,5MLU,5NL0,5O9G,5OMX,5ONG,5ONW,5OXV,5OY7,5WCU,5X0X,5X0Y,5X7X,5XF3,5XF4,5XF5,5XF6,5XM0,5XM1,5Y0C,5Y0D,5Z23,5Z30,5Z3L,5Z3O,5Z3U,5Z3V,5ZBX,6A5L,6A5O,6A5P,6A5R,6A5T,6A5U,6BUZ,6C0W,6DZT,6E0C,6E0P,6ESF,6ESG,6ESH,6ESI,6FML,6FQ5,6FQ6,6FQ8,6FTX,6G0L,6HKT,6HTS,6I84,6INQ,6IPU,6IQ4,6IR9,6IRO,6IY2,6IY3,6J4W,6J4X,6J4Y,6J4Z,6J50,6J51,6J99,6JM9,6JMA,6JOU,6JR0,6JR1,6JXD,6JYL,6K1I,6K1J,6K1K,6K1P,6KE9,6KIU,6KIV,6KIW,6KIX,6KIZ,6KVD,6KW3,6KW4,6KW5,6KXV,6L49,6L4A,6L9H,6L9Z,6LA2,6LA8,6LA9,6LAB,6LE9,6LER,6LTJ,6M3V,6M44,6M4D,6M4G,6M4H,6MUO,6MUP,6NE3,6NJ9,6NN6,6NOG,6NQA,6NZO,6O1D,6O22,6O96,6OM3,6PA7,6PWV,6PWW,6PWX,6PX1,6PX3,6R0C,6R1T,6R1U,6R25,6R8Y,6R8Z,6R90,6R91,6R92,6R93,6R94,6RNY,6RYR,6RYU,6S01,6SE0,6SE6,6SEE,6SEF,6SEG,6T79,6T7A,6T7B,6T7C,6T7D,6T90,6T93,6T9L,6TDA,6TEM,6UGM,6UH5,6UPK,6UPL,6USJ,6UXW,6V2K,6V92,6VEN,6VYP,6VZ4,6W5I,6W5M,6W5N,6WKR,6WZ5,6WZ9,6X0N,6X59,6X5A,6XJD,6Y5D,6Y5E,6YN1,6YOV,6Z6P,6ZHX,6ZHY,7A08,7AT8,7BWD,7BXT,7BY0,7C0M,7CCQ,7CCR,7CIZ,7CJ0,7COW,7CRO,7CRP,7CRQ,7CRR,7D1Z,7D20,7DBH,7DBP,7E8D,7E8I,7EA5,7EA8,7EG6,7EGP,7ENN,7JO9,7JOA,7JZV,7K5X,7K5Y,7K60,7K61,7K63,7K6P,7K6Q,7KBD,7KBE,7KBF,7KTQ,7LYA,7LYB,7LYC,7M1X,7MBM,7MBN,7NKX,7NKY,7NL0,7OH9,7OHA,7OHB,7OHC,7OTQ,7PET,7PEU,7PEV,7PEW,7PEX,7PEY,7PEZ,7PF0,7PF2,7PF3,7PF4,7PF5,7PF6,7PFA,7PFC,7PFD,7PFE,7PFF,7PFT,7PFU,7PFV,7PFW,7PFX,7PGV,7PGW,7PH5,7PH6,7PII,7R5R,7SCY,7SCZ,7SSA,7SWY,7TAN,7TN2,7U0G,7U0I,7U0J,7U46,7U47,7U4D,7U50,7U51,7U52,7U53,7UD5,7UNC,7UND,7UNK,7UV9,7UX9,7V1M,7V6Q,7V90,7V96,7V9C,7V9J,7V9K,7V9S,7VA4,7VBM,7VCQ,7VDT,7VDV,7VVU,7VVZ,7VZ4,7W9V,7WBV,7WBW,7WBX,7X57,7X58,7XAY,7XCR,7XCT,7XD0,7XD1,7XFC,7XFH,7XFI,7XFL,7XFM,7XFN,7XNP,7XPX,7XSE,7XSX,7XSZ,7XT7,7XTD,7XTI,7XVL,7XVM,7XX5,7XX6,7XX7,7XZX,7XZY,7XZZ,7Y00,7Y5U,7Y5V,7Y5W,7Y60,7Y61,7Y7I,7Y8R,7YI1,7YI4,7YI5,7YOZ,7YQK,7YRD,7YWX,7YYH,7ZI4,7ZS9,7ZSA,7ZSB,8AAG,8ATF,8AV6,8BVW,8BYQ,8BZ1,8CEO,8CWW,8CZE,8DK5,8DU4,8ETT,8ETV,8EU2,8EUE,8EUJ,8F86,8G57,8G86,8G88,8G8B,8G8G,8GPN,8GRM,8GRQ,8H0V,8H0W,8H1T,8HAG,8HAH,8HAI,8HAJ,8HAK,8HAL,8HAM,8HAN,8HE5,8IQF,8IQG,8J6S,8J6T,8OF4,8OO7,8OOA,8OOP,8OOS,8OSJ,8OSK,8OSL,8OTS,8OTT,8PC5,8PC6,8PEO,8PEP,8SIY,8SPS,8SPU	Histone H4	H4_HUMAN	P62805	A2VCL0 P02304 P02305 Q6DRA9 Q6FGB8 Q6NWP7