BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 1055492 Nc1ccc2ccccc2c1\N=N\c1ccc(\C=C\c2ccc(cc2S(O)(=O)=O)\N=N\c2c(N)ccc3ccccc23)c(c1)S(O)(=O)=O InChI=1S/C34H26N6O6S2/c35-29-17-13-21-5-1-3-7-27(21)33(29)39-37-25-15-11-23(31(19-25)47(41,42)43)9-10-24-12-16-26(20-32(24)48(44,45)46)38-40-34-28-8-4-2-6-22(28)14-18-30(34)36/h1-20H,35-36H2,(H,41,42,43)(H,44,45,46)/b10-9+,39-37+,40-38+ ANGMGEOZQHWOBK-NKPXSSHVSA-N 103826 SPI-01::US11041859, Code SPI-01::US9791447, Compound SPI-01 Sentrin-specific protease/Small ubiquitin-related modifier 2 Homo sapiens 1100 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=334&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103826&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search 5463294 172541640 2 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 1U4A,1WM2,1WM3,2AWT,2CKH,2D07,2IO0,2IO1,2IO3,2IYD,2MP2,2N1W,2N9E,2RPQ,3UIN,3UIO,3ZO5,4BKG,5D2M,5ELU,5EQL,5GHB,5GHC,5TVQ,6JXW,6JXX,6K5R,6NNQ,7R2E Small ubiquitin-related modifier 2 SUMO2_HUMAN P61956 B2R4I2 P55855 Q32Q42 Q6IPZ6 Q96HK1 MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 1TGZ,1TH0 Sentrin-specific protease 2 SENP2_HUMAN Q9HC62 B4DQ42 Q8IW97 Q96SR2 Q9P2L5 1055496 Cc1cc(ccc1\N=N\c1c(N)ccc2cc(ccc12)S(O)(=O)=O)-c1ccc(\N=N\c2c(N)c(cc3cc(ccc23)S(O)(=O)=O)S(O)(=O)=O)c(C)c1 InChI=1S/C34H28N6O9S3/c1-18-13-20(4-11-29(18)37-39-33-26-8-6-24(50(41,42)43)15-22(26)3-10-28(33)35)21-5-12-30(19(2)14-21)38-40-34-27-9-7-25(51(44,45)46)16-23(27)17-31(32(34)36)52(47,48)49/h3-17H,35-36H2,1-2H3,(H,41,42,43)(H,44,45,46)(H,47,48,49)/b39-37+,40-38+ OFGVQLJUXSRVEG-HVMBLDELSA-N 103827 SPI-02::US11041859, Code SPI-02::US9791447, Compound SPI-02 Sentrin-specific protease/Small ubiquitin-related modifier 2 Homo sapiens 2700 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=334&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103827&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search 408832 172541641 2 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 1U4A,1WM2,1WM3,2AWT,2CKH,2D07,2IO0,2IO1,2IO3,2IYD,2MP2,2N1W,2N9E,2RPQ,3UIN,3UIO,3ZO5,4BKG,5D2M,5ELU,5EQL,5GHB,5GHC,5TVQ,6JXW,6JXX,6K5R,6NNQ,7R2E Small ubiquitin-related modifier 2 SUMO2_HUMAN P61956 B2R4I2 P55855 Q32Q42 Q6IPZ6 Q96HK1 MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 1TGZ,1TH0 Sentrin-specific protease 2 SENP2_HUMAN Q9HC62 B4DQ42 Q8IW97 Q96SR2 Q9P2L5 1055500 Cc1cc(ccc1-c1ccc(cc1C)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O InChI=1S/C34H28N6O6S2/c1-19-15-21(37-39-29-17-31(47(41,42)43)25-7-3-5-9-27(25)33(29)35)11-13-23(19)24-14-12-22(16-20(24)2)38-40-30-18-32(48(44,45)46)26-8-4-6-10-28(26)34(30)36/h3-18H,35-36H2,1-2H3,(H,41,42,43)(H,44,45,46)/b39-37+,40-38+ UVHHADIQQIICAV-HVMBLDELSA-N 103828 SPI-03::US11041859, Code SPI-03 Sentrin-specific protease/Small ubiquitin-related modifier 2 Homo sapiens 3000 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=334&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103828&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search 407700 172541642 2 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 1U4A,1WM2,1WM3,2AWT,2CKH,2D07,2IO0,2IO1,2IO3,2IYD,2MP2,2N1W,2N9E,2RPQ,3UIN,3UIO,3ZO5,4BKG,5D2M,5ELU,5EQL,5GHB,5GHC,5TVQ,6JXW,6JXX,6K5R,6NNQ,7R2E Small ubiquitin-related modifier 2 SUMO2_HUMAN P61956 B2R4I2 P55855 Q32Q42 Q6IPZ6 Q96HK1 MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 1TGZ,1TH0 Sentrin-specific protease 2 SENP2_HUMAN Q9HC62 B4DQ42 Q8IW97 Q96SR2 Q9P2L5 1055504 Nc1ccc(\N=N\c2ccc(\C=C\c3ccc(cc3S(O)(=O)=O)\N=N\c3ccc(N)c4ccc(cc34)S([O-])(=O)=O)c(c2)S(O)(=O)=O)c2cc(ccc12)S(O)(=O)=O InChI=1S/C34H26N6O12S4/c35-29-11-13-31(27-17-23(53(41,42)43)7-9-25(27)29)39-37-21-5-3-19(33(15-21)55(47,48)49)1-2-20-4-6-22(16-34(20)56(50,51)52)38-40-32-14-12-30(36)26-10-8-24(18-28(26)32)54(44,45)46/h1-18H,35-36H2,(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)/p-1/b2-1+,39-37+,40-38+ SNXAXOIRGVVISE-FDEKBVFPSA-M 103829 SPI-04::US11041859, Code SPI-04::US9791447, Compound SPI-04 Sentrin-specific protease/Small ubiquitin-related modifier 2 Homo sapiens 2150 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=334&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103829&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search 91899657 172541643 2 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 1U4A,1WM2,1WM3,2AWT,2CKH,2D07,2IO0,2IO1,2IO3,2IYD,2MP2,2N1W,2N9E,2RPQ,3UIN,3UIO,3ZO5,4BKG,5D2M,5ELU,5EQL,5GHB,5GHC,5TVQ,6JXW,6JXX,6K5R,6NNQ,7R2E Small ubiquitin-related modifier 2 SUMO2_HUMAN P61956 B2R4I2 P55855 Q32Q42 Q6IPZ6 Q96HK1 MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 1TGZ,1TH0 Sentrin-specific protease 2 SENP2_HUMAN Q9HC62 B4DQ42 Q8IW97 Q96SR2 Q9P2L5 1055508 Nc1ccc(\N=N\c2ccc(\C=C\c3ccc(cc3S(O)(=O)=O)\N=N\c3ccc(N)c4ccccc34)c(c2)S(O)(=O)=O)c2ccccc12 InChI=1S/C34H26N6O6S2/c35-29-15-17-31(27-7-3-1-5-25(27)29)39-37-23-13-11-21(33(19-23)47(41,42)43)9-10-22-12-14-24(20-34(22)48(44,45)46)38-40-32-18-16-30(36)26-6-2-4-8-28(26)32/h1-20H,35-36H2,(H,41,42,43)(H,44,45,46)/b10-9+,39-37+,40-38+ BEOHKTZPLVXCFG-NKPXSSHVSA-N 103830 SPI-05::US11041859, Code SPI-05::US9791447, Compound SPI-05 Sentrin-specific protease/Small ubiquitin-related modifier 2 Homo sapiens 4600 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=334&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103830&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search 5463299 172541644 2 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 1U4A,1WM2,1WM3,2AWT,2CKH,2D07,2IO0,2IO1,2IO3,2IYD,2MP2,2N1W,2N9E,2RPQ,3UIN,3UIO,3ZO5,4BKG,5D2M,5ELU,5EQL,5GHB,5GHC,5TVQ,6JXW,6JXX,6K5R,6NNQ,7R2E Small ubiquitin-related modifier 2 SUMO2_HUMAN P61956 B2R4I2 P55855 Q32Q42 Q6IPZ6 Q96HK1 MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 1TGZ,1TH0 Sentrin-specific protease 2 SENP2_HUMAN Q9HC62 B4DQ42 Q8IW97 Q96SR2 Q9P2L5 1055512 Cc1ccccc1\N=N\c1cc(c2ccccc2c1N)S([O-])(=O)=O InChI=1S/C17H15N3O3S/c1-11-6-2-5-9-14(11)19-20-15-10-16(24(21,22)23)12-7-3-4-8-13(12)17(15)18/h2-10H,18H2,1H3,(H,21,22,23)/p-1/b20-19+ PIWJSAOBFMHEAW-FMQUCBEESA-M 348888 NSC70551::US11041859, Code SPI-06::US9791447, Compound SPI-06 Sentrin-specific protease/Small ubiquitin-related modifier 2 Homo sapiens 10700 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=334&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348888&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search 139208472 386050649 2 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 1U4A,1WM2,1WM3,2AWT,2CKH,2D07,2IO0,2IO1,2IO3,2IYD,2MP2,2N1W,2N9E,2RPQ,3UIN,3UIO,3ZO5,4BKG,5D2M,5ELU,5EQL,5GHB,5GHC,5TVQ,6JXW,6JXX,6K5R,6NNQ,7R2E Small ubiquitin-related modifier 2 SUMO2_HUMAN P61956 B2R4I2 P55855 Q32Q42 Q6IPZ6 Q96HK1 MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 1TGZ,1TH0 Sentrin-specific protease 2 SENP2_HUMAN Q9HC62 B4DQ42 Q8IW97 Q96SR2 Q9P2L5 1055516 Cc1cc(N)ccc1\N=N\c1cc(c2cccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O InChI=1S/C17H15N3O6S2/c1-10-7-11(18)5-6-15(10)20-19-12-8-14-13(17(9-12)28(24,25)26)3-2-4-16(14)27(21,22)23/h2-9H,18H2,1H3,(H,21,22,23)(H,24,25,26)/p-2/b20-19+ XXZDPVOWJBCNQC-FMQUCBEESA-L 103832 SPI-07::US11041859, Code SPI-07 Sentrin-specific protease/Small ubiquitin-related modifier 2 Homo sapiens 28060 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=334&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103832&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search 91899658 172541646 2 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 1U4A,1WM2,1WM3,2AWT,2CKH,2D07,2IO0,2IO1,2IO3,2IYD,2MP2,2N1W,2N9E,2RPQ,3UIN,3UIO,3ZO5,4BKG,5D2M,5ELU,5EQL,5GHB,5GHC,5TVQ,6JXW,6JXX,6K5R,6NNQ,7R2E Small ubiquitin-related modifier 2 SUMO2_HUMAN P61956 B2R4I2 P55855 Q32Q42 Q6IPZ6 Q96HK1 MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 1TGZ,1TH0 Sentrin-specific protease 2 SENP2_HUMAN Q9HC62 B4DQ42 Q8IW97 Q96SR2 Q9P2L5 1055520 Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c1ccccc1 InChI=1S/C16H13N3O3S/c17-16-13-9-5-4-8-12(13)15(23(20,21)22)10-14(16)19-18-11-6-2-1-3-7-11/h1-10H,17H2,(H,20,21,22)/p-1/b19-18+ NVHYKPCSIVPAAM-VHEBQXMUSA-M 103833 SPI-08::US11041859, Code SPI-08::US9791447, Compound SPI-08 Sentrin-specific protease/Small ubiquitin-related modifier 2 Homo sapiens 41060 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=334&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103833&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search 91899659 172541647 2 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 1U4A,1WM2,1WM3,2AWT,2CKH,2D07,2IO0,2IO1,2IO3,2IYD,2MP2,2N1W,2N9E,2RPQ,3UIN,3UIO,3ZO5,4BKG,5D2M,5ELU,5EQL,5GHB,5GHC,5TVQ,6JXW,6JXX,6K5R,6NNQ,7R2E Small ubiquitin-related modifier 2 SUMO2_HUMAN P61956 B2R4I2 P55855 Q32Q42 Q6IPZ6 Q96HK1 MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 1TGZ,1TH0 Sentrin-specific protease 2 SENP2_HUMAN Q9HC62 B4DQ42 Q8IW97 Q96SR2 Q9P2L5 1055524 Nc1ccc2cc(cc(c2c1\N=N\c1ccc(cc1)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O InChI=1S/C16H13N3O9S3/c17-13-6-1-9-7-12(30(23,24)25)8-14(31(26,27)28)15(9)16(13)19-18-10-2-4-11(5-3-10)29(20,21)22/h1-8H,17H2,(H,20,21,22)(H,23,24,25)(H,26,27,28)/b19-18+ NPWGMYKQRGYORG-VHEBQXMUSA-N 103834 SPI-09::US11041859, Code SPI-09::US9791447, Compound SPI-09 Sentrin-specific protease/Small ubiquitin-related modifier 2 Homo sapiens 26600 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=334&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103834&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search 412845 172541648 2 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 1U4A,1WM2,1WM3,2AWT,2CKH,2D07,2IO0,2IO1,2IO3,2IYD,2MP2,2N1W,2N9E,2RPQ,3UIN,3UIO,3ZO5,4BKG,5D2M,5ELU,5EQL,5GHB,5GHC,5TVQ,6JXW,6JXX,6K5R,6NNQ,7R2E Small ubiquitin-related modifier 2 SUMO2_HUMAN P61956 B2R4I2 P55855 Q32Q42 Q6IPZ6 Q96HK1 MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 1TGZ,1TH0 Sentrin-specific protease 2 SENP2_HUMAN Q9HC62 B4DQ42 Q8IW97 Q96SR2 Q9P2L5 1055528 Nc1ccc(\N=N\c2cccc(c2)S([O-])(=O)=O)c2ccccc12 InChI=1S/C16H13N3O3S/c17-15-8-9-16(14-7-2-1-6-13(14)15)19-18-11-4-3-5-12(10-11)23(20,21)22/h1-10H,17H2,(H,20,21,22)/p-1/b19-18+ COAVSGQDMBDKLG-VHEBQXMUSA-M 103835 SPI-10::US11041859, Code SPI-10::US9791447, Compound SPI-10 Sentrin-specific protease/Small ubiquitin-related modifier 2 Homo sapiens 36440 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=334&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103835&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+2&column=ki&startPg=0&Increment=50&submit=Search 91899660 172541649 2 MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY 1U4A,1WM2,1WM3,2AWT,2CKH,2D07,2IO0,2IO1,2IO3,2IYD,2MP2,2N1W,2N9E,2RPQ,3UIN,3UIO,3ZO5,4BKG,5D2M,5ELU,5EQL,5GHB,5GHC,5TVQ,6JXW,6JXX,6K5R,6NNQ,7R2E Small ubiquitin-related modifier 2 SUMO2_HUMAN P61956 B2R4I2 P55855 Q32Q42 Q6IPZ6 Q96HK1 MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNSSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGCNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHCTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTETMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNSDLNLLEWTHHSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL 1TGZ,1TH0 Sentrin-specific protease 2 SENP2_HUMAN Q9HC62 B4DQ42 Q8IW97 Q96SR2 Q9P2L5