BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 1055489 Nc1ccc2ccccc2c1\N=N\c1ccc(\C=C\c2ccc(cc2S(O)(=O)=O)\N=N\c2c(N)ccc3ccccc23)c(c1)S(O)(=O)=O InChI=1S/C34H26N6O6S2/c35-29-17-13-21-5-1-3-7-27(21)33(29)39-37-25-15-11-23(31(19-25)47(41,42)43)9-10-24-12-16-26(20-32(24)48(44,45)46)38-40-34-28-8-4-2-6-22(28)14-18-30(34)36/h1-20H,35-36H2,(H,41,42,43)(H,44,45,46)/b10-9+,39-37+,40-38+ ANGMGEOZQHWOBK-NKPXSSHVSA-N 103826 SPI-01::US11041859, Code SPI-01::US9791447, Compound SPI-01 Sentrin-specific protease/Small ubiquitin-related modifier 1 Homo sapiens 32800 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=331&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103826&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search 5463294 172541640 2 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 1TGZ,1WYW,1Y8R,1Z5S,2ASQ,2BF8,2G4D,2IO2,2IY0,2IY1,2KQS,2LAS,2MW5,2N1A,2N1V,2PE6,2UYZ,2VRR,3UIP,5B7A,5ELJ,5GHD,6JXU,6JXV,6K5T,6XOG,6XOH,6XOI,8ODR Small ubiquitin-related modifier 1 SUMO1_HUMAN P63165 A8MUS8 B2R4I5 P55856 Q6FGG0 Q6NZ62 Q93068 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 2IYC,2IYD,2XRE Sentrin-specific protease 1 SENP1_HUMAN Q9P0U3 A8K7P5 Q86XC8 1055493 Cc1cc(ccc1\N=N\c1c(N)ccc2cc(ccc12)S(O)(=O)=O)-c1ccc(\N=N\c2c(N)c(cc3cc(ccc23)S(O)(=O)=O)S(O)(=O)=O)c(C)c1 InChI=1S/C34H28N6O9S3/c1-18-13-20(4-11-29(18)37-39-33-26-8-6-24(50(41,42)43)15-22(26)3-10-28(33)35)21-5-12-30(19(2)14-21)38-40-34-27-9-7-25(51(44,45)46)16-23(27)17-31(32(34)36)52(47,48)49/h3-17H,35-36H2,1-2H3,(H,41,42,43)(H,44,45,46)(H,47,48,49)/b39-37+,40-38+ OFGVQLJUXSRVEG-HVMBLDELSA-N 103827 SPI-02::US11041859, Code SPI-02::US9791447, Compound SPI-02 Sentrin-specific protease/Small ubiquitin-related modifier 1 Homo sapiens 26500 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=331&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103827&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search 408832 172541641 2 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 1TGZ,1WYW,1Y8R,1Z5S,2ASQ,2BF8,2G4D,2IO2,2IY0,2IY1,2KQS,2LAS,2MW5,2N1A,2N1V,2PE6,2UYZ,2VRR,3UIP,5B7A,5ELJ,5GHD,6JXU,6JXV,6K5T,6XOG,6XOH,6XOI,8ODR Small ubiquitin-related modifier 1 SUMO1_HUMAN P63165 A8MUS8 B2R4I5 P55856 Q6FGG0 Q6NZ62 Q93068 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 2IYC,2IYD,2XRE Sentrin-specific protease 1 SENP1_HUMAN Q9P0U3 A8K7P5 Q86XC8 1055497 Cc1cc(ccc1-c1ccc(cc1C)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O InChI=1S/C34H28N6O6S2/c1-19-15-21(37-39-29-17-31(47(41,42)43)25-7-3-5-9-27(25)33(29)35)11-13-23(19)24-14-12-22(16-20(24)2)38-40-30-18-32(48(44,45)46)26-8-4-6-10-28(26)34(30)36/h3-18H,35-36H2,1-2H3,(H,41,42,43)(H,44,45,46)/b39-37+,40-38+ UVHHADIQQIICAV-HVMBLDELSA-N 103828 SPI-03::US11041859, Code SPI-03 Sentrin-specific protease/Small ubiquitin-related modifier 1 Homo sapiens 20270 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=331&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103828&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search 407700 172541642 2 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 1TGZ,1WYW,1Y8R,1Z5S,2ASQ,2BF8,2G4D,2IO2,2IY0,2IY1,2KQS,2LAS,2MW5,2N1A,2N1V,2PE6,2UYZ,2VRR,3UIP,5B7A,5ELJ,5GHD,6JXU,6JXV,6K5T,6XOG,6XOH,6XOI,8ODR Small ubiquitin-related modifier 1 SUMO1_HUMAN P63165 A8MUS8 B2R4I5 P55856 Q6FGG0 Q6NZ62 Q93068 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 2IYC,2IYD,2XRE Sentrin-specific protease 1 SENP1_HUMAN Q9P0U3 A8K7P5 Q86XC8 1055501 Nc1ccc(\N=N\c2ccc(\C=C\c3ccc(cc3S(O)(=O)=O)\N=N\c3ccc(N)c4ccc(cc34)S([O-])(=O)=O)c(c2)S(O)(=O)=O)c2cc(ccc12)S(O)(=O)=O InChI=1S/C34H26N6O12S4/c35-29-11-13-31(27-17-23(53(41,42)43)7-9-25(27)29)39-37-21-5-3-19(33(15-21)55(47,48)49)1-2-20-4-6-22(16-34(20)56(50,51)52)38-40-32-14-12-30(36)26-10-8-24(18-28(26)32)54(44,45)46/h1-18H,35-36H2,(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)/p-1/b2-1+,39-37+,40-38+ SNXAXOIRGVVISE-FDEKBVFPSA-M 103829 SPI-04::US11041859, Code SPI-04::US9791447, Compound SPI-04 Sentrin-specific protease/Small ubiquitin-related modifier 1 Homo sapiens 11200 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=331&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103829&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search 91899657 172541643 2 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 1TGZ,1WYW,1Y8R,1Z5S,2ASQ,2BF8,2G4D,2IO2,2IY0,2IY1,2KQS,2LAS,2MW5,2N1A,2N1V,2PE6,2UYZ,2VRR,3UIP,5B7A,5ELJ,5GHD,6JXU,6JXV,6K5T,6XOG,6XOH,6XOI,8ODR Small ubiquitin-related modifier 1 SUMO1_HUMAN P63165 A8MUS8 B2R4I5 P55856 Q6FGG0 Q6NZ62 Q93068 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 2IYC,2IYD,2XRE Sentrin-specific protease 1 SENP1_HUMAN Q9P0U3 A8K7P5 Q86XC8 1055505 Nc1ccc(\N=N\c2ccc(\C=C\c3ccc(cc3S(O)(=O)=O)\N=N\c3ccc(N)c4ccccc34)c(c2)S(O)(=O)=O)c2ccccc12 InChI=1S/C34H26N6O6S2/c35-29-15-17-31(27-7-3-1-5-25(27)29)39-37-23-13-11-21(33(19-23)47(41,42)43)9-10-22-12-14-24(20-34(22)48(44,45)46)38-40-32-18-16-30(36)26-6-2-4-8-28(26)32/h1-20H,35-36H2,(H,41,42,43)(H,44,45,46)/b10-9+,39-37+,40-38+ BEOHKTZPLVXCFG-NKPXSSHVSA-N 103830 SPI-05::US11041859, Code SPI-05::US9791447, Compound SPI-05 Sentrin-specific protease/Small ubiquitin-related modifier 1 Homo sapiens >60000 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=331&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103830&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search 5463299 172541644 2 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 1TGZ,1WYW,1Y8R,1Z5S,2ASQ,2BF8,2G4D,2IO2,2IY0,2IY1,2KQS,2LAS,2MW5,2N1A,2N1V,2PE6,2UYZ,2VRR,3UIP,5B7A,5ELJ,5GHD,6JXU,6JXV,6K5T,6XOG,6XOH,6XOI,8ODR Small ubiquitin-related modifier 1 SUMO1_HUMAN P63165 A8MUS8 B2R4I5 P55856 Q6FGG0 Q6NZ62 Q93068 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 2IYC,2IYD,2XRE Sentrin-specific protease 1 SENP1_HUMAN Q9P0U3 A8K7P5 Q86XC8 1055509 Cc1ccccc1\N=N\c1cc(c2ccccc2c1N)S([O-])(=O)=O InChI=1S/C17H15N3O3S/c1-11-6-2-5-9-14(11)19-20-15-10-16(24(21,22)23)12-7-3-4-8-13(12)17(15)18/h2-10H,18H2,1H3,(H,21,22,23)/p-1/b20-19+ PIWJSAOBFMHEAW-FMQUCBEESA-M 348888 NSC70551::US11041859, Code SPI-06::US9791447, Compound SPI-06 Sentrin-specific protease/Small ubiquitin-related modifier 1 Homo sapiens >60000 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=331&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348888&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search 139208472 386050649 2 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 1TGZ,1WYW,1Y8R,1Z5S,2ASQ,2BF8,2G4D,2IO2,2IY0,2IY1,2KQS,2LAS,2MW5,2N1A,2N1V,2PE6,2UYZ,2VRR,3UIP,5B7A,5ELJ,5GHD,6JXU,6JXV,6K5T,6XOG,6XOH,6XOI,8ODR Small ubiquitin-related modifier 1 SUMO1_HUMAN P63165 A8MUS8 B2R4I5 P55856 Q6FGG0 Q6NZ62 Q93068 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 2IYC,2IYD,2XRE Sentrin-specific protease 1 SENP1_HUMAN Q9P0U3 A8K7P5 Q86XC8 1055513 Cc1cc(N)ccc1\N=N\c1cc(c2cccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O InChI=1S/C17H15N3O6S2/c1-10-7-11(18)5-6-15(10)20-19-12-8-14-13(17(9-12)28(24,25)26)3-2-4-16(14)27(21,22)23/h2-9H,18H2,1H3,(H,21,22,23)(H,24,25,26)/p-2/b20-19+ XXZDPVOWJBCNQC-FMQUCBEESA-L 103832 SPI-07::US11041859, Code SPI-07 Sentrin-specific protease/Small ubiquitin-related modifier 1 Homo sapiens >60000 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=331&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103832&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search 91899658 172541646 2 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 1TGZ,1WYW,1Y8R,1Z5S,2ASQ,2BF8,2G4D,2IO2,2IY0,2IY1,2KQS,2LAS,2MW5,2N1A,2N1V,2PE6,2UYZ,2VRR,3UIP,5B7A,5ELJ,5GHD,6JXU,6JXV,6K5T,6XOG,6XOH,6XOI,8ODR Small ubiquitin-related modifier 1 SUMO1_HUMAN P63165 A8MUS8 B2R4I5 P55856 Q6FGG0 Q6NZ62 Q93068 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 2IYC,2IYD,2XRE Sentrin-specific protease 1 SENP1_HUMAN Q9P0U3 A8K7P5 Q86XC8 1055517 Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c1ccccc1 InChI=1S/C16H13N3O3S/c17-16-13-9-5-4-8-12(13)15(23(20,21)22)10-14(16)19-18-11-6-2-1-3-7-11/h1-10H,17H2,(H,20,21,22)/p-1/b19-18+ NVHYKPCSIVPAAM-VHEBQXMUSA-M 103833 SPI-08::US11041859, Code SPI-08::US9791447, Compound SPI-08 Sentrin-specific protease/Small ubiquitin-related modifier 1 Homo sapiens >60000 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=331&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103833&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search 91899659 172541647 2 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 1TGZ,1WYW,1Y8R,1Z5S,2ASQ,2BF8,2G4D,2IO2,2IY0,2IY1,2KQS,2LAS,2MW5,2N1A,2N1V,2PE6,2UYZ,2VRR,3UIP,5B7A,5ELJ,5GHD,6JXU,6JXV,6K5T,6XOG,6XOH,6XOI,8ODR Small ubiquitin-related modifier 1 SUMO1_HUMAN P63165 A8MUS8 B2R4I5 P55856 Q6FGG0 Q6NZ62 Q93068 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 2IYC,2IYD,2XRE Sentrin-specific protease 1 SENP1_HUMAN Q9P0U3 A8K7P5 Q86XC8 1055521 Nc1ccc2cc(cc(c2c1\N=N\c1ccc(cc1)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O InChI=1S/C16H13N3O9S3/c17-13-6-1-9-7-12(30(23,24)25)8-14(31(26,27)28)15(9)16(13)19-18-10-2-4-11(5-3-10)29(20,21)22/h1-8H,17H2,(H,20,21,22)(H,23,24,25)(H,26,27,28)/b19-18+ NPWGMYKQRGYORG-VHEBQXMUSA-N 103834 SPI-09::US11041859, Code SPI-09::US9791447, Compound SPI-09 Sentrin-specific protease/Small ubiquitin-related modifier 1 Homo sapiens >60000 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=331&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103834&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search 412845 172541648 2 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 1TGZ,1WYW,1Y8R,1Z5S,2ASQ,2BF8,2G4D,2IO2,2IY0,2IY1,2KQS,2LAS,2MW5,2N1A,2N1V,2PE6,2UYZ,2VRR,3UIP,5B7A,5ELJ,5GHD,6JXU,6JXV,6K5T,6XOG,6XOH,6XOI,8ODR Small ubiquitin-related modifier 1 SUMO1_HUMAN P63165 A8MUS8 B2R4I5 P55856 Q6FGG0 Q6NZ62 Q93068 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 2IYC,2IYD,2XRE Sentrin-specific protease 1 SENP1_HUMAN Q9P0U3 A8K7P5 Q86XC8 1055525 Nc1ccc(\N=N\c2cccc(c2)S([O-])(=O)=O)c2ccccc12 InChI=1S/C16H13N3O3S/c17-15-8-9-16(14-7-2-1-6-13(14)15)19-18-11-4-3-5-12(10-11)23(20,21)22/h1-10H,17H2,(H,20,21,22)/p-1/b19-18+ COAVSGQDMBDKLG-VHEBQXMUSA-M 103835 SPI-10::US11041859, Code SPI-10::US9791447, Compound SPI-10 Sentrin-specific protease/Small ubiquitin-related modifier 1 Homo sapiens >60000 US Patent 10.7270/Q29W0JKM aid1805669 US11041859 Chen, Y; Chen, C; Namanja, A CITY OF HOPE http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=103835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=331&target=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=103835&enzyme=Sentrin-specific+protease%2FSmall+ubiquitin-related+modifier+1&column=ki&startPg=0&Increment=50&submit=Search 91899660 172541649 2 MSDQEAKPSTEDLGDKKEGEYIKLKVIGQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTGGHSTV 1TGZ,1WYW,1Y8R,1Z5S,2ASQ,2BF8,2G4D,2IO2,2IY0,2IY1,2KQS,2LAS,2MW5,2N1A,2N1V,2PE6,2UYZ,2VRR,3UIP,5B7A,5ELJ,5GHD,6JXU,6JXV,6K5T,6XOG,6XOH,6XOI,8ODR Small ubiquitin-related modifier 1 SUMO1_HUMAN P63165 A8MUS8 B2R4I5 P55856 Q6FGG0 Q6NZ62 Q93068 MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL 2IYC,2IYD,2XRE Sentrin-specific protease 1 SENP1_HUMAN Q9P0U3 A8K7P5 Q86XC8