BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID	PubChem SID	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
50782534	CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-n2nc(-c3ccc(OCCN4CCOCC4)cc3)c3c(N)ncnc23)no1	InChI=1S/C31H35N9O4/c1-31(2,3)24-18-25(38-44-24)36-30(41)35-21-6-8-22(9-7-21)40-29-26(28(32)33-19-34-29)27(37-40)20-4-10-23(11-5-20)43-17-14-39-12-15-42-16-13-39/h4-11,18-19H,12-17H2,1-3H3,(H2,32,33,34)(H2,35,36,38,41)	SKDBXDGKLQALIZ-UHFFFAOYSA-N	50250180	CHEMBL4101411	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.7b00840	10.7270/Q2474D9S	28956923			Wang, A; Li, X; Chen, C; Wu, H; Qi, Z; Hu, C; Yu, K; Wu, J; Liu, J; Liu, X; Hu, Z; Wang, W; Wang, W; Wang, W; Wang, L; Wang, B; Liu, Q; Li, L; Ge, J; Ren, T; Zhang, S; Xia, R; Liu, J; Liu, Q	Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50250180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50250180&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			132204257	401961934							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50519833	C[C@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=N)(=O)C2CC2)ncc1C(F)(F)F	InChI=1S/C18H21F3N4O3S/c1-10(26)11(2)28-16-15(18(19,20)21)9-23-17(25-16)24-12-3-5-13(6-4-12)29(22,27)14-7-8-14/h3-6,9-11,14,22,26H,7-8H2,1-2H3,(H,23,24,25)/t10-,11+,29?/m0/s1	UELYDGOOJPRWGF-DUFANNBHSA-N	50193085	CHEMBL3925525	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 25							ChEMBL	10.1021/acs.jmedchem.6b00150	10.7270/Q2G73GP8	27171036			Sonawane, YA; Taylor, MA; Napoleon, JV; Rana, S; Contreras, JI; Natarajan, A	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193085&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134140883	375076095		CHEMBL3925525					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50519876	CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1	InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)	UZWDCWONPYILKI-UHFFFAOYSA-N	50110183	Abemaciclib::LY-2835219::US10662186, Compound LY2835219::US10696678, Example LY2835219::US10988476, Compound LY2835219::US11053238, LY2835219::US11091476, Example LY2835219::US11351170, Example Abemaciclib	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 3910								ChEMBL	10.1021/acs.jmedchem.6b00150	10.7270/Q2G73GP8	27171036			Sonawane, YA; Taylor, MA; Napoleon, JV; Rana, S; Contreras, JI; Natarajan, A	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110183&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	6ZV	7O7K,7O7J,5L2S,7SJ3	46220502	319493137							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50519877	CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl	InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1	BIIVYFLTOXDAOV-YVEFUNNKSA-N	5655	2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one::CHEMBL428690::Flavopiridol::US10294218, Example Flavopiridol::US9617225, Flavopiridol	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 514							ChEMBL	10.1021/acs.jmedchem.6b00150	10.7270/Q2G73GP8	27171036			Sonawane, YA; Taylor, MA; Napoleon, JV; Rana, S; Contreras, JI; Natarajan, A	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5655&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	CPB	1C8K,1E1Y,3BLR,3EBP,4O71	5287969	8035270		CHEMBL428690	DB03496	5680		ZINC21288966	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50519921	CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1	InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)	OUSFTKFNBAZUKL-UHFFFAOYSA-N	5931	BMS-387072::CHEMBL296468::N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide::N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide::cid_3025986	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62							ChEMBL	10.1021/acs.jmedchem.6b00150	10.7270/Q2G73GP8	27171036			Sonawane, YA; Taylor, MA; Napoleon, JV; Rana, S; Contreras, JI; Natarajan, A	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5931&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	56H	5D1J	3025986	8035540		CHEMBL296468		5670		ZINC03816409	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50519959	CN1CC[C@H]([C@@H]1CO)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl	InChI=1S/C21H20ClNO5/c1-23-7-6-12(14(23)10-24)19-15(25)8-16(26)20-17(27)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,14,24-26H,6-7,10H2,1H3/t12-,14+/m1/s1	QLUYMIVVAYRECT-OCCSQVGLSA-N	50193086	CHEMBL3969723	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2870							ChEMBL	10.1021/acs.jmedchem.6b00150	10.7270/Q2G73GP8	27171036			Sonawane, YA; Taylor, MA; Napoleon, JV; Rana, S; Contreras, JI; Natarajan, A	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193086	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193086&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			23643976	375076096		CHEMBL3969723					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50519974	CN1C\C=C\CCOc2cccc(c2)-c2ccnc(Nc3cccc(C1)c3)n2	InChI=1S/C23H24N4O/c1-27-13-3-2-4-14-28-21-10-6-8-19(16-21)22-11-12-24-23(26-22)25-20-9-5-7-18(15-20)17-27/h2-3,5-12,15-16H,4,13-14,17H2,1H3,(H,24,25,26)/b3-2+	VXBAJLGYBMTJCY-NSCUHMNNSA-N	50363196	CHEMBL1944698	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.0							ChEMBL	10.1021/acs.jmedchem.6b00150	10.7270/Q2G73GP8	27171036			Sonawane, YA; Taylor, MA; Napoleon, JV; Rana, S; Contreras, JI; Natarajan, A	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50363196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50363196&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			16739650	136967258		CHEMBL1944698				ZINC68251500	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50519975	Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1	InChI=1S/C16H17Cl2N5O2/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9/h1-3,8-9,19H,4-7H2,(H,20,23)(H,21,25)(H,22,24)	OVPNQJVDAFNBDN-UHFFFAOYSA-N	50113281	AT-7519	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 2800								ChEMBL	10.1021/acs.jmedchem.6b00150	10.7270/Q2G73GP8	27171036			Sonawane, YA; Taylor, MA; Napoleon, JV; Rana, S; Contreras, JI; Natarajan, A	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113281&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	LZE	7AGA,2VU3	11338033	104007630			DB08142			ZINC13473650	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50519986	CC(C)c1n(C)nc2ccc(cc12)-c1ccnc(N[C@H]2CC[C@@H](CC2)NC2CCOCC2)n1	InChI=1S/C26H36N6O/c1-17(2)25-22-16-18(4-9-24(22)31-32(25)3)23-10-13-27-26(30-23)29-20-7-5-19(6-8-20)28-21-11-14-33-15-12-21/h4,9-10,13,16-17,19-21,28H,5-8,11-12,14-15H2,1-3H3,(H,27,29,30)/t19-,20-	LHIUZPIDLZYPRL-MXVIHJGJSA-N	50193097	CHEMBL3940387	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 246							ChEMBL	10.1021/acs.jmedchem.6b00150	10.7270/Q2G73GP8	27171036			Sonawane, YA; Taylor, MA; Napoleon, JV; Rana, S; Contreras, JI; Natarajan, A	University of Nebraska Medical Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193097&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			78357764	375076107		CHEMBL3940387					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51070413	NC1CCC(CC1)Nc1nc(NCc2ccc(nc2)-c2ccccc2O)c2ncn(C3CCCC3)c2n1	InChI=1S/C28H34N8O/c29-19-10-12-20(13-11-19)33-28-34-26(25-27(35-28)36(17-32-25)21-5-1-2-6-21)31-16-18-9-14-23(30-15-18)22-7-3-4-8-24(22)37/h3-4,7-9,14-15,17,19-21,37H,1-2,5-6,10-13,16,29H2,(H2,31,33,34,35)	UVKLAINVJNUJNX-UHFFFAOYSA-N	50437236	CHEMBL2402946	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 306							ChEMBL	10.1021/jm4006884	10.7270/Q2FX7BVZ	23829517			Gucky, T; Jorda, R; Zatloukal, M; Bazgier, V; Berka, K; Reznickova, E; Beres, T; Strnad, M; Krystof, V	Palack£ University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50437236	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50437236&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			71664364	175449553		CHEMBL2402946				ZINC96273135	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50547265	CC1(C)C(=O)N([C@H]2CCc3c2cccc3O)c2nc(Nc3ccccc3)ncc12	InChI=1S/C23H22N4O2/c1-23(2)17-13-24-22(25-14-7-4-3-5-8-14)26-20(17)27(21(23)29)18-12-11-16-15(18)9-6-10-19(16)28/h3-10,13,18,28H,11-12H2,1-2H3,(H,24,25,26)/t18-/m0/s1	XLFNLJYGUOLEJS-SFHVURJKSA-N	50208911	CHEMBL3884319	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 793							ChEMBL	10.1016/j.bmcl.2016.08.068	10.7270/Q2N018JC	27816515			Katz, JD; Haidle, A; Childers, KK; Zabierek, AA; Jewell, JP; Hou, Y; Altman, MD; Szewczak, A; Chen, D; Harsch, A; Hayashi, M; Warren, L; Hutton, M; Nuthall, H; Su, HP; Munshi, S; Stanton, MG; Davies, IW; Munoz, B; Northrup, A	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208911	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208911&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			69036886	375982220		CHEMBL3884319					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50953870	COc1ccc(cc1)C(=O)NC1CCN(CC1)c1nccc(Nc2ccc(F)cc2)n1	InChI=1S/C23H24FN5O2/c1-31-20-8-2-16(3-9-20)22(30)27-19-11-14-29(15-12-19)23-25-13-10-21(28-23)26-18-6-4-17(24)5-7-18/h2-10,13,19H,11-12,14-15H2,1H3,(H,27,30)(H,25,26,28)	SBNVUFMJQUOIKN-UHFFFAOYSA-N	50274791	CHEMBL4127826	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 90							ChEMBL	10.1016/j.bmc.2018.05.024	10.7270/Q26M399K	29853338			Wang, Y; Chen, Y; Cheng, X; Zhang, K; Wang, H; Liu, B; Wang, J	Shihezi University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274791	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274791&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145961292	405257021							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51112052	CC(C)c1n[nH]c2c(NCc3ccccc3)nc(NC3CCCCC3N)nc12	InChI=1S/C21H29N7/c1-13(2)17-18-19(28-27-17)20(23-12-14-8-4-3-5-9-14)26-21(25-18)24-16-11-7-6-10-15(16)22/h3-5,8-9,13,15-16H,6-7,10-12,22H2,1-2H3,(H,27,28)(H2,23,24,25,26)	NVTINYQXFHNHIJ-UHFFFAOYSA-N	50454182	CHEMBL4210771	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							ChEMBL	10.1016/j.bmc.2017.10.012	10.7270/Q25141T6	29273417			Cherukupalli, S; Hampannavar, GA; Chinnam, S; Chandrasekaran, B; Sayyad, N; Kayamba, F; Reddy Aleti, R; Karpoormath, R	University of KwaZulu-Natal	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454182&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			49793229	433922566							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51112068	CC(C)c1n[nH]c2c(NCc3ccccc3)nc(NC3CCC(N)CC3)nc12	InChI=1S/C21H29N7/c1-13(2)17-18-19(28-27-17)20(23-12-14-6-4-3-5-7-14)26-21(25-18)24-16-10-8-15(22)9-11-16/h3-7,13,15-16H,8-12,22H2,1-2H3,(H,27,28)(H2,23,24,25,26)	XGFAWOAQXUCOCE-UHFFFAOYSA-N	50454184	CHEMBL4205015	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							ChEMBL	10.1016/j.bmc.2017.10.012	10.7270/Q25141T6	29273417			Cherukupalli, S; Hampannavar, GA; Chinnam, S; Chandrasekaran, B; Sayyad, N; Kayamba, F; Reddy Aleti, R; Karpoormath, R	University of KwaZulu-Natal	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50454184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50454184&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			49835655	433922568							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51098826	Cn1cc(cn1)-c1ccc(cc1)S(=O)(=O)N1CCC(CC1)Nc1ccc(cn1)C#N	InChI=1S/C21H22N6O2S/c1-26-15-18(14-24-26)17-3-5-20(6-4-17)30(28,29)27-10-8-19(9-11-27)25-21-7-2-16(12-22)13-23-21/h2-7,13-15,19H,8-11H2,1H3,(H,23,25)	MBFRPRCYZAVISU-UHFFFAOYSA-N	50367737	CHEMBL4173631	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.8b00683	10.7270/Q2HX1G6F	30067358			Ito, M; Tanaka, T; Toita, A; Uchiyama, N; Kokubo, H; Morishita, N; Klein, MG; Zou, H; Murakami, M; Kondo, M; Sameshima, T; Araki, S; Endo, S; Kawamoto, T; Morin, GB; Aparicio, SA; Nakanishi, A; Maezaki, H; Imaeda, Y	Takeda Pharmaceutical Company Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367737&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145951220	160846839						ZINC04433167	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51098830	Cn1cc(ccc1=O)-c1ccc(cc1)N([C@H]1CC[C@@H](CC1)Nc1ccc(cn1)C#N)C(=O)NCc1ccccc1	InChI=1S/C32H32N6O2/c1-37-22-26(10-18-31(37)39)25-8-13-28(14-9-25)38(32(40)35-20-23-5-3-2-4-6-23)29-15-11-27(12-16-29)36-30-17-7-24(19-33)21-34-30/h2-10,13-14,17-18,21-22,27,29H,11-12,15-16,20H2,1H3,(H,34,36)(H,35,40)/t27-,29-	HDJBGURZVALLMD-KWQFAZJVSA-N	50367676	CHEMBL4160662	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.8b00683	10.7270/Q2HX1G6F	30067358			Ito, M; Tanaka, T; Toita, A; Uchiyama, N; Kokubo, H; Morishita, N; Klein, MG; Zou, H; Murakami, M; Kondo, M; Sameshima, T; Araki, S; Endo, S; Kawamoto, T; Morin, GB; Aparicio, SA; Nakanishi, A; Maezaki, H; Imaeda, Y	Takeda Pharmaceutical Company Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367676&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134813906	160846778						ZINC49774918	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51098852	Cn1cc(cn1)-c1ccc(cc1)N([C@@H]1CC[C@@H](CC1)Nc1ccc(cn1)C#N)C(=O)NCc1ccccc1	InChI=1S/C30H31N7O/c1-36-21-25(20-34-36)24-8-12-27(13-9-24)37(30(38)33-18-22-5-3-2-4-6-22)28-14-10-26(11-15-28)35-29-16-7-23(17-31)19-32-29/h2-9,12-13,16,19-21,26,28H,10-11,14-15,18H2,1H3,(H,32,35)(H,33,38)/t26-,28+	KHMZQQYEYPDOBI-DBAYTGFXSA-N	50367849	CHEMBL4175774	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.8b00683	10.7270/Q2HX1G6F	30067358			Ito, M; Tanaka, T; Toita, A; Uchiyama, N; Kokubo, H; Morishita, N; Klein, MG; Zou, H; Murakami, M; Kondo, M; Sameshima, T; Araki, S; Endo, S; Kawamoto, T; Morin, GB; Aparicio, SA; Nakanishi, A; Maezaki, H; Imaeda, Y	Takeda Pharmaceutical Company Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367849&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145950134	160846951						ZINC22064534	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51098862	CC(C)C(=O)OC[C@@H]1O[C@H]([C@@H](O)[C@@H]1O)n1cnc(N)c2c(C(N)=O)c(Br)nc12	InChI=1S/C16H20BrN5O6/c1-5(2)16(26)27-3-6-9(23)10(24)15(28-6)22-4-20-12(18)8-7(13(19)25)11(17)21-14(8)22/h4-6,9-10,15,23-24H,3,18H2,1-2H3,(H2,19,25)/t6-,9+,10-,15+/m0/s1	FECJFYFWBIAIIL-WYLSKWGASA-N	50367682	CHEMBL4162128	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1200							ChEMBL	10.1021/acs.jmedchem.8b00683	10.7270/Q2HX1G6F	30067358			Ito, M; Tanaka, T; Toita, A; Uchiyama, N; Kokubo, H; Morishita, N; Klein, MG; Zou, H; Murakami, M; Kondo, M; Sameshima, T; Araki, S; Endo, S; Kawamoto, T; Morin, GB; Aparicio, SA; Nakanishi, A; Maezaki, H; Imaeda, Y	Takeda Pharmaceutical Company Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50367682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50367682&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145958217	160846784						ZINC49049619	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51098865	CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	HKSZLNNOFSGOKW-FYTWVXJKSA-N	2579	(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::CHEMBL388978::Staurosporin, 4::Staurosporine::Staurosporine, 8::US9206188, Staurosporine::US9226923, Staurosporine	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 120							ChEMBL	10.1021/acs.jmedchem.8b00683	10.7270/Q2HX1G6F	30067358			Ito, M; Tanaka, T; Toita, A; Uchiyama, N; Kokubo, H; Morishita, N; Klein, MG; Zou, H; Murakami, M; Kondo, M; Sameshima, T; Araki, S; Endo, S; Kawamoto, T; Morin, GB; Aparicio, SA; Nakanishi, A; Maezaki, H; Imaeda, Y	Takeda Pharmaceutical Company Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=2579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=2579&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	STO	1AQ1,1BYG,1E8Z,1NVR,1NXK,1OKY,1Q3D,1QPD,1QPJ,1SM2,1SNU,1STC,1U59,1WVY,1XBC,1XJD,1YHS,2BUJ,2CLQ,2DQ7,2GCD,2HW7,2ITQ,2ITU,2ITW,2NRY,2OIC	44259	8032349	15738	CHEMBL388978		346	C02079	ZINC03814434	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51137042	COCCN[C@H]1CC[C@@H](CC1)Nc1cc(-c2csc(NCC3(CCOCC3)C#N)n2)c(Cl)cn1	InChI=1S/C24H33ClN6O2S/c1-32-11-8-27-17-2-4-18(5-3-17)30-22-12-19(20(25)13-28-22)21-14-34-23(31-21)29-16-24(15-26)6-9-33-10-7-24/h12-14,17-18,27H,2-11,16H2,1H3,(H,28,30)(H,29,31)/t17-,18-	XSDZPPRQLIZLDG-IYARVYRRSA-N	50466210	CHEMBL4281048	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1720							ChEMBL	10.1016/j.ejmech.2018.09.025	10.7270/Q2DJ5J9D	30253346			Wang, B; Wu, J; Wu, Y; Chen, C; Zou, F; Wang, A; Wu, H; Hu, Z; Jiang, Z; Liu, Q; Wang, W; Zhang, Y; Liu, F; Zhao, M; Hu, J; Huang, T; Ge, J; Wang, L; Ren, T; Wang, Y; Liu, J; Liu, Q	Chinese Academy of Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50466210	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50466210&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134814484	433933475							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50839545	Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Br)c3)ncnc12	InChI=1S/C23H22BrN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+	QYLYUTQSYHCBOD-HDICACEKSA-N	50261163	CHEMBL4081756	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 359							ChEMBL	10.1016/j.bmcl.2017.08.018	10.7270/Q2W66P60	28827110			Park, SJ; Kim, E; Yoo, M; Lee, JY; Park, CH; Hwang, JY; Ha, JD	Korea Research Institute of Chemical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261163	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261163&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137646454	404340624							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50839553	Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Cl)c3)ncnc12	InChI=1S/C23H22ClN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+	GGRVRRFOVWKWMD-HDICACEKSA-N	50261164	CHEMBL4103221	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 319							ChEMBL	10.1016/j.bmcl.2017.08.018	10.7270/Q2W66P60	28827110			Park, SJ; Kim, E; Yoo, M; Lee, JY; Park, CH; Hwang, JY; Ha, JD	Korea Research Institute of Chemical Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50261164	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50261164&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137657453	404340625							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51139053	CC(=O)N1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1ncnn2ccc(C3CCOCC3)c12	InChI=1S/C23H34N6O2/c1-17(30)27-10-12-28(13-11-27)20-4-2-19(3-5-20)26-23-22-21(18-7-14-31-15-8-18)6-9-29(22)25-16-24-23/h6,9,16,18-20H,2-5,7-8,10-15H2,1H3,(H,24,25,26)/t19-,20-	SWPXADMCNLNAGW-MXVIHJGJSA-N	50466825	CHEMBL4290222	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 516							ChEMBL	10.1016/j.bmc.2018.01.008	10.7270/Q2MW2KTQ	29398441			Degorce, SL; Anjum, R; Dillman, KS; Drew, L; Groombridge, SD; Halsall, CT; Lenz, EM; Lindsay, NA; Mayo, MF; Pink, JH; Robb, GR; Scott, JS; Stokes, S; Xue, Y	AstraZeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50466825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50466825&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138728749	433934090							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51139094	CC(C)c1ccn2ncnc(N[C@H]3CC[C@@H](CC3)N3CCN(CC3)C(C)=O)c12	InChI=1S/C21H32N6O/c1-15(2)19-8-9-27-20(19)21(22-14-23-27)24-17-4-6-18(7-5-17)26-12-10-25(11-13-26)16(3)28/h8-9,14-15,17-18H,4-7,10-13H2,1-3H3,(H,22,23,24)/t17-,18-	FQBRQRVXPUQKLG-IYARVYRRSA-N	50466824	CHEMBL4278882	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>30000							ChEMBL	10.1016/j.bmc.2018.01.008	10.7270/Q2MW2KTQ	29398441			Degorce, SL; Anjum, R; Dillman, KS; Drew, L; Groombridge, SD; Halsall, CT; Lenz, EM; Lindsay, NA; Mayo, MF; Pink, JH; Robb, GR; Scott, JS; Stokes, S; Xue, Y	AstraZeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50466824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50466824&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145979845	433934089							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51139015	CC(=O)N1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1ncnn2ccc(C3CCOCC3)c12	InChI=1S/C23H34N6O2/c1-17(30)27-10-12-28(13-11-27)20-4-2-19(3-5-20)26-23-22-21(18-7-14-31-15-8-18)6-9-29(22)25-16-24-23/h6,9,16,18-20H,2-5,7-8,10-15H2,1H3,(H,24,25,26)/t19-,20-	SWPXADMCNLNAGW-MXVIHJGJSA-N	50466825	CHEMBL4290222	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>30000							ChEMBL	10.1016/j.bmc.2018.01.008	10.7270/Q2MW2KTQ	29398441			Degorce, SL; Anjum, R; Dillman, KS; Drew, L; Groombridge, SD; Halsall, CT; Lenz, EM; Lindsay, NA; Mayo, MF; Pink, JH; Robb, GR; Scott, JS; Stokes, S; Xue, Y	AstraZeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50466825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50466825&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138728749	433934090							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51139020	CC(C)c1ccn2ncnc(N[C@H]3CC[C@@H](CC3)N3CCN(CC3)C(C)=O)c12	InChI=1S/C21H32N6O/c1-15(2)19-8-9-27-20(19)21(22-14-23-27)24-17-4-6-18(7-5-17)26-12-10-25(11-13-26)16(3)28/h8-9,14-15,17-18H,4-7,10-13H2,1-3H3,(H,22,23,24)/t17-,18-	FQBRQRVXPUQKLG-IYARVYRRSA-N	50466824	CHEMBL4278882	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2310							ChEMBL	10.1016/j.bmc.2018.01.008	10.7270/Q2MW2KTQ	29398441			Degorce, SL; Anjum, R; Dillman, KS; Drew, L; Groombridge, SD; Halsall, CT; Lenz, EM; Lindsay, NA; Mayo, MF; Pink, JH; Robb, GR; Scott, JS; Stokes, S; Xue, Y	AstraZeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50466824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50466824&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145979845	433934089							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
902957	CN1CCN(CC1)c1ccc(Nc2nccc(n2)N2C(=O)NCC22CCCCC2)nc1	InChI=1S/C22H30N8O/c1-28-11-13-29(14-12-28)17-5-6-18(24-15-17)26-20-23-10-7-19(27-20)30-21(31)25-16-22(30)8-3-2-4-9-22/h5-7,10,15H,2-4,8-9,11-14,16H2,1H3,(H,25,31)(H,23,24,26,27)	RBSNIGHOISZVRA-UHFFFAOYSA-N	443113	US10654831, Compound 6	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 95900							US Patent		10.7270/Q2JS9TFP		aid1804412	US10654831	Strum, JC; Gaston, RD; Gadwood, RC	G1 Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=443113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=443113&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138595677	440074298							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
902960	CN1CC2(CCCCC2)N(C1=O)c1ccnc(Nc2ccc(cn2)N2CCN(C)CC2)n1	InChI=1S/C23H32N8O/c1-28-12-14-30(15-13-28)18-6-7-19(25-16-18)26-21-24-11-8-20(27-21)31-22(32)29(2)17-23(31)9-4-3-5-10-23/h6-8,11,16H,3-5,9-10,12-15,17H2,1-2H3,(H,24,25,26,27)	BCZJHZOLBWWRJF-UHFFFAOYSA-N	443114	US10654831, Compound 8	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q2JS9TFP		aid1804412	US10654831	Strum, JC; Gaston, RD; Gadwood, RC	G1 Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=443114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=443114&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138595627	440074299							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
902963	CN1CCN(CC1)c1ccc(Nc2nccc(n2)N2C(=O)N(Cc3ccccc3)CC22CCCCC2)nc1	InChI=1S/C29H36N8O/c1-34-16-18-35(19-17-34)24-10-11-25(31-20-24)32-27-30-15-12-26(33-27)37-28(38)36(21-23-8-4-2-5-9-23)22-29(37)13-6-3-7-14-29/h2,4-5,8-12,15,20H,3,6-7,13-14,16-19,21-22H2,1H3,(H,30,31,32,33)	KAJDQFDBXWMHBD-UHFFFAOYSA-N	443115	US10654831, Compound 10	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q2JS9TFP		aid1804412	US10654831	Strum, JC; Gaston, RD; Gadwood, RC	G1 Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=443115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=443115&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138595641	440074300							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
902966	CN1CCN(CC1)c1ccc(Nc2nccc(n2)N2CCNC2=O)nc1	InChI=1S/C17H22N8O/c1-23-8-10-24(11-9-23)13-2-3-14(20-12-13)21-16-18-5-4-15(22-16)25-7-6-19-17(25)26/h2-5,12H,6-11H2,1H3,(H,19,26)(H,18,20,21,22)	FMPXDCWCCUNMBZ-UHFFFAOYSA-N	443116	US10654831, Compound 16	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 29400							US Patent		10.7270/Q2JS9TFP		aid1804412	US10654831	Strum, JC; Gaston, RD; Gadwood, RC	G1 Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=443116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=443116&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138595639	440074301							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
902969	CN1CCN(CC1)c1ccc(Nc2nccc(n2)N2CC(=O)NCC22CCCCC2)nc1	InChI=1S/C23H32N8O/c1-29-11-13-30(14-12-29)18-5-6-19(25-15-18)27-22-24-10-7-20(28-22)31-16-21(32)26-17-23(31)8-3-2-4-9-23/h5-7,10,15H,2-4,8-9,11-14,16-17H2,1H3,(H,26,32)(H,24,25,27,28)	WYBDIAZRTPZHAJ-UHFFFAOYSA-N	443117	US10654831, Compound 20	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q2JS9TFP		aid1804412	US10654831	Strum, JC; Gaston, RD; Gadwood, RC	G1 Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=443117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=443117&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138595618	440074302							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
902973	CN1CCN(CC1)c1ccc(Nc2nccc(n2)N2C(=NCC22CCCCC2)c2ccccc2)nc1	InChI=1S/C28H34N8/c1-34-16-18-35(19-17-34)23-10-11-24(30-20-23)32-27-29-15-12-25(33-27)36-26(22-8-4-2-5-9-22)31-21-28(36)13-6-3-7-14-28/h2,4-5,8-12,15,20H,3,6-7,13-14,16-19,21H2,1H3,(H,29,30,32,33)	LHBYGETUNLHPQT-UHFFFAOYSA-N	443123	US10654831, Compound 53	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q2JS9TFP		aid1804412	US10654831	Strum, JC; Gaston, RD; Gadwood, RC	G1 Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=443123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=443123&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138595616	440074308							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
902976	CN1CCN(CC1)c1ccc(Nc2nccc(n2)N2C(=NCC22CCCCC2)c2ccoc2)nc1	InChI=1S/C26H32N8O/c1-32-12-14-33(15-13-32)21-5-6-22(28-17-21)30-25-27-11-7-23(31-25)34-24(20-8-16-35-18-20)29-19-26(34)9-3-2-4-10-26/h5-8,11,16-18H,2-4,9-10,12-15,19H2,1H3,(H,27,28,30,31)	YVKZJQMOPKJPBN-UHFFFAOYSA-N	443124	US10654831, Compound 54	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q2JS9TFP		aid1804412	US10654831	Strum, JC; Gaston, RD; Gadwood, RC	G1 Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=443124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=443124&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138595617	440074309							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
902979	CN1CCN(CC1)c1ccc(Nc2nccc(n2)N2C(=NCC22CCCCC2)c2ccsc2)nc1	InChI=1S/C26H32N8S/c1-32-12-14-33(15-13-32)21-5-6-22(28-17-21)30-25-27-11-7-23(31-25)34-24(20-8-16-35-18-20)29-19-26(34)9-3-2-4-10-26/h5-8,11,16-18H,2-4,9-10,12-15,19H2,1H3,(H,27,28,30,31)	UDQUHQJBHHLXTB-UHFFFAOYSA-N	443125	US10654831, Compound 55	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q2JS9TFP		aid1804412	US10654831	Strum, JC; Gaston, RD; Gadwood, RC	G1 Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=443125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=443125&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138595669	440074310							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51251882	CN1C\C=C\CCOc2cccc(c2)-c2ccnc(Nc3cccc(C1)c3)n2	InChI=1S/C23H24N4O/c1-27-13-3-2-4-14-28-21-10-6-8-19(16-21)22-11-12-24-23(26-22)25-20-9-5-7-18(15-20)17-27/h2-3,5-12,15-16H,4,13-14,17H2,1H3,(H,24,25,26)/b3-2+	VXBAJLGYBMTJCY-NSCUHMNNSA-N	50363196	CHEMBL1944698	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 37							ChEMBL	10.1021/acs.jmedchem.8b01469	10.7270/Q26Q21J2	30543440			Tadesse, S; Caldon, EC; Tilley, W; Wang, S	University of South Australia Cancer Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50363196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50363196&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			16739650	136967258		CHEMBL1944698				ZINC68251500	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51251909	C[C@@H](O)[C@@H](C)Oc1nc(Nc2ccc(cc2)S(=N)(=O)C2CC2)ncc1C(F)(F)F	InChI=1S/C18H21F3N4O3S/c1-10(26)11(2)28-16-15(18(19,20)21)9-23-17(25-16)24-12-3-5-13(6-4-12)29(22,27)14-7-8-14/h3-6,9-11,14,22,26H,7-8H2,1-2H3,(H,23,24,25)/t10-,11-,29?/m1/s1	UELYDGOOJPRWGF-MFOHZAOFSA-N	50511926	CHEMBL4442620	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 25							ChEMBL	10.1021/acs.jmedchem.8b01469	10.7270/Q26Q21J2	30543440			Tadesse, S; Caldon, EC; Tilley, W; Wang, S	University of South Australia Cancer Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50511926	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50511926&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	R0N	5IEV	45380979	440720508							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51251928	Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1	InChI=1S/C16H17Cl2N5O2/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9/h1-3,8-9,19H,4-7H2,(H,20,23)(H,21,25)(H,22,24)	OVPNQJVDAFNBDN-UHFFFAOYSA-N	50113281	AT-7519	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2400							ChEMBL	10.1021/acs.jmedchem.8b01469	10.7270/Q26Q21J2	30543440			Tadesse, S; Caldon, EC; Tilley, W; Wang, S	University of South Australia Cancer Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113281&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	LZE	7AGA,2VU3	11338033	104007630			DB08142			ZINC13473650	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51234559	CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)CCOCCOCCOCCNC(=O)CCC1=[N+]2C(C=C1)=Cc1c(C)cc(C)n1[B-]2(F)F	InChI=1S/C50H56BF2N7O7/c1-30-26-31(2)59-39(30)27-33-15-14-32(60(33)51(59,52)53)16-17-41(61)54-18-20-64-22-24-66-25-23-65-21-19-56(4)40-28-42-57-37-12-8-6-10-34(37)44-45-36(29-55-49(45)62)43-35-11-7-9-13-38(35)58(47(43)46(44)57)50(3,67-42)48(40)63-5/h6-15,26-27,40,42,48H,16-25,28-29H2,1-5H3,(H,54,61)(H,55,62)/t40-,42-,48-,50+/m1/s1	OSVUGUHRKMMBSE-INMRTLOZSA-N	50505542	CHEMBL4576489	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens			 819						ChEMBL	10.1016/j.bmcl.2019.126641	10.7270/Q2RV0S0K	31526603			Hirozane, Y; Toyofuku, M; Yogo, T; Tanaka, Y; Sameshima, T; Miyahisa, I; Yoshikawa, M	Takeda Pharmaceutical Company Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50505542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50505542&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			155552127	440714127							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51234661	CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)NCCOCCOCCOCCNC(=O)CCC1=[N+]2C(C=C1)=Cc1c(C)cc(C)n1[B-]2(F)F	InChI=1S/C49H54BF2N7O7/c1-29-25-30(2)58-39(29)26-32-14-13-31(59(32)50(58,51)52)15-16-40(60)54-18-20-64-22-24-65-23-21-63-19-17-53-36-27-41-56-37-11-7-5-9-33(37)43-44-35(28-55-48(44)61)42-34-10-6-8-12-38(34)57(46(42)45(43)56)49(3,66-41)47(36)62-4/h5-14,25-26,36,41,47,53H,15-24,27-28H2,1-4H3,(H,54,60)(H,55,61)/t36-,41-,47-,49+/m1/s1	NXSJMRCTGYTSTK-SQHKIPTKSA-N	50505541	CHEMBL4465866	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens			 894						ChEMBL	10.1016/j.bmcl.2019.126641	10.7270/Q2RV0S0K	31526603			Hirozane, Y; Toyofuku, M; Yogo, T; Tanaka, Y; Sameshima, T; Miyahisa, I; Yoshikawa, M	Takeda Pharmaceutical Company Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50505541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50505541&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			155531579	440714126							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51222459	CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2ccc3CN(CCN(C)C)CCc3n2)ncc1F	InChI=1S/C27H32F2N8/c1-16(2)37-17(3)31-26-20(28)12-19(13-23(26)37)25-21(29)14-30-27(34-25)33-24-7-6-18-15-36(11-10-35(4)5)9-8-22(18)32-24/h6-7,12-14,16H,8-11,15H2,1-5H3,(H,30,32,33,34)	KGMVZSJAPXYTKH-UHFFFAOYSA-N	444543	US10662186, Compound 63::US10988476, Compound I-63	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1217							ChEMBL	10.1016/j.ejmech.2019.06.005	10.7270/Q20K2CTJ	31200237			Shi, C; Wang, Q; Liao, X; Ge, H; Huo, G; Zhang, L; Chen, N; Zhai, X; Hong, Y; Wang, L; Han, Y; Xiao, W; Wang, Z; Shi, W; Mao, Y; Yu, J; Xia, G; Liu, Y	Shanghai Pharmaceuticals Holding Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444543&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			130196825	440706790							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51238772	CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	HKSZLNNOFSGOKW-FYTWVXJKSA-N	2579	(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::CHEMBL388978::Staurosporin, 4::Staurosporine::Staurosporine, 8::US9206188, Staurosporine::US9226923, Staurosporine	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 76.6							ChEMBL	10.1016/j.ejmech.2018.10.052	10.7270/Q2W380MT	30384048			Narayan, S; Ramisetti, S; Jaiswal, AS; Law, BK; Singh-Pillay, A; Singh, P; Amin, S; Sharma, AK	University of Florida	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=2579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=2579&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	STO	1AQ1,1BYG,1E8Z,1NVR,1NXK,1OKY,1Q3D,1QPD,1QPJ,1SM2,1SNU,1STC,1U59,1WVY,1XBC,1XJD,1YHS,2BUJ,2CLQ,2DQ7,2GCD,2HW7,2ITQ,2ITU,2ITW,2NRY,2OIC	44259	8032349	15738	CHEMBL388978		346	C02079	ZINC03814434	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225411	Clc1[nH]c2ccccc2c1\C=C1\C(=O)Nc2ccccc12	InChI=1S/C17H11ClN2O/c18-16-12(10-5-1-3-7-14(10)19-16)9-13-11-6-2-4-8-15(11)20-17(13)21/h1-9,19H,(H,20,21)/b13-9+	QJKBRWSJWQVKLY-UKTHLTGXSA-N	50375670	CHEMBL261425	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 16000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375670&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			5472558	160854760		CHEMBL261425				ZINC01662968	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225412	CN1CCN(CC1)c1ccc(Nc2ncc3cc(C#N)c(=O)n(C4CCCC4)c3n2)cc1	InChI=1S/C24H27N7O/c1-29-10-12-30(13-11-29)20-8-6-19(7-9-20)27-24-26-16-18-14-17(15-25)23(32)31(22(18)28-24)21-4-2-3-5-21/h6-9,14,16,21H,2-5,10-13H2,1H3,(H,26,27,28)	VADOZMZXXRBXNY-UHFFFAOYSA-N	50447512	CHEMBL3115681	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50447512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50447512&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			56649281	194945408		CHEMBL3115681					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225413	CCCCOc1c(c[nH]c2nncc12)C(=O)c1c(F)cc(C)cc1F	InChI=1S/C18H17F2N3O2/c1-3-4-5-25-17-11(8-21-18-12(17)9-22-23-18)16(24)15-13(19)6-10(2)7-14(15)20/h6-9H,3-5H2,1-2H3,(H,21,22,23)	SCFMWQIQBVZOQR-UHFFFAOYSA-N	50503350	CHEMBL310840	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1600							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503350&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			135402864	440711935							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225506	O=C1N=C(NCc2cccs2)SC1=Cc1ccc2ncccc2c1	InChI=1S/C18H13N3OS2/c22-17-16(24-18(21-17)20-11-14-4-2-8-23-14)10-12-5-6-15-13(9-12)3-1-7-19-15/h1-10H,11H2,(H,20,21,22)	XOLMRFUGOINFDQ-UHFFFAOYSA-N	50205472	(5Z)-5-(quinolin-6-ylmethylidene)-2-[(thiophen-2-ylmethyl)amino]-1,3-thiazol-4(5H)-one::(Z)-5-(quinolin-6-ylmethylene)-2-(thiophen-2-ylmethylamino)thiazol-4(5H)-one::CHEMBL261644::CHEMBL393929	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 17400							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50205472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50205472&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	1RO	5O12,4EOI,4EOL,4EON,4EOP,4EOS	11631681	104083820		CHEMBL261644CHEMBL393929				ZINC28821265	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225507	CCn1cnc2c(Nc3cccc(Cl)c3)nc(N[C@@H]3CCCC[C@@H]3N)nc12	InChI=1S/C19H24ClN7/c1-2-27-11-22-16-17(23-13-7-5-6-12(20)10-13)25-19(26-18(16)27)24-15-9-4-3-8-14(15)21/h5-7,10-11,14-15H,2-4,8-9,21H2,1H3,(H2,23,24,25,26)/t14-,15+/m0/s1	UTBSBSOBZHXMHI-LSDHHAIUSA-N	50073765	CHEMBL367625::N*2*-((1R,2S)-2-Amino-cyclohexyl)-N*6*-(3-chloro-phenyl)-9-ethyl-9H-purine-2,6-diamine	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 279							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50073765	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50073765&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	FC8	6GUK,6GU4	2794188	103967051		CHEMBL367625		5945		ZINC02583998	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225508	CNC(=O)c1nn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc-21	InChI=1S/C25H32N8O/c1-25(2)14-16-15-27-24(29-20(16)22-19(25)21(23(34)26-3)30-32(22)5)28-17-6-8-18(9-7-17)33-12-10-31(4)11-13-33/h6-9,15H,10-14H2,1-5H3,(H,26,34)(H,27,28,29)	RXZMYLDMFYNEIM-UHFFFAOYSA-N	31545	Milciclib::pyrazolo[4,3-h]quinazoline-3-carboxamide, 28	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 270							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31545&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	P48	2WIH,5VD1,5VC6	16718576	172097446						ZINC53119602	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225509	COc1ccc(CNc2nc(nc3n(cnc23)C(C)C)N(CCO)CCO)cc1	InChI=1S/C20H28N6O3/c1-14(2)26-13-22-17-18(21-12-15-4-6-16(29-3)7-5-15)23-20(24-19(17)26)25(8-10-27)9-11-28/h4-7,13-14,27-28H,8-12H2,1-3H3,(H,21,23,24)	NQVIIUBWMBHLOZ-UHFFFAOYSA-N	50113739	2(bis-(hydroxyethyl)amino)-6-(4-methoxybenzylamino)-9-isopropyl-purine::2-(bis-(hydroxylethyl)amino)-6-(4-methoxybenzylamino)-9-isopropylpurine::2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-benzylamino)-9H-purin-2-yl]-amino}-ethanol::CHEMBL80713	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9200							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113739&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	AJR	6INL	6918386	104007999		CHEMBL80713		5948		ZINC01487345	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225510	O=C1Nc2ccc3ncsc3c2\C1=C\Nc1ccc(cc1)S(=O)(=O)Nc1ccccn1	InChI=1S/C21H15N5O3S2/c27-21-15(19-16(25-21)8-9-17-20(19)30-12-24-17)11-23-13-4-6-14(7-5-13)31(28,29)26-18-3-1-2-10-22-18/h1-12,23H,(H,22,26)(H,25,27)/b15-11-	GCYXEGSPUDSZJY-PTNGSMBKSA-N	153742	Oxindole (Scaffold V)	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 317							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=153742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=153742&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			6539118	253650861							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225511	CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n(C2CCCC2)c1=O	InChI=1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29)	AHJRHEGDXFFMBM-UHFFFAOYSA-N	6309	6-Acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one Hydrochloride::8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::Ibrance::PD 0332991::Palbociclib::Pyrido-[2,3-d]-pyrimidin-7-one 43::US10189849, PD0332991::US10464927, Compound Palbociclib::US10696682, Compound PD0332991::US10927120, PD0332991::US9464092, PD0332991::US9957276, PD0332991	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6309&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	LQQ	2EUF,5L2I,7N7O	5330286	8035907			DB09073			ZINC03938686	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225512	CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1	InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28)	RHXHGRAEPCAFML-UHFFFAOYSA-N	148264	7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide::Kisqali::LEE011::Ribociclib::US10570141, Comparative Example 1::US8962630, 74	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>20000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=148264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=148264&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	6ZZ	5L2T	44631912	252148259							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225513	O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21	InChI=1S/C20H11N3O2/c24-19-15-13-9-5-1-3-7-11(9)21-17(13)18-14(16(15)20(25)23-19)10-6-2-4-8-12(10)22-18/h1-8,21-22H,(H,23,24,25)	KAJXOWFGKYKMMZ-UHFFFAOYSA-N	2672	3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaene-12,14-dione::6,7,12,13-Tetrahydro-5,7-dioxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole::CHEMBL268368::arcyriaflavin A	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>20000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=2672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=2672&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			5327723	8032440		CHEMBL268368				ZINC12354940	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225514	COc1ccc(OC)c2c1[nH]c1ccccc1c2=S	InChI=1S/C15H13NO2S/c1-17-11-7-8-12(18-2)14-13(11)15(19)9-5-3-4-6-10(9)16-14/h3-8H,1-2H3,(H,16,19)	KFAKESMKRPNZTM-UHFFFAOYSA-N	59089	NSC625987	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>20000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=59089	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=59089&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			3004085	123080305						ZINC06404102	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225515	CCCOc1cnc(CNC=C2C(=O)NC(=O)c3ccc(I)cc23)cc1O	InChI=1S/C19H18IN3O4/c1-2-5-27-17-10-22-12(7-16(17)24)8-21-9-15-14-6-11(20)3-4-13(14)18(25)23-19(15)26/h3-4,6-7,9-10,21H,2,5,8H2,1H3,(H,22,24)(H,23,25,26)	DXMZEMWEDCPBNA-UHFFFAOYSA-N	50267480	4-{[(4-Hydroxy-5-propoxy-pyridin-2-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione::CHEMBL477064	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>20000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50267480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50267480&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			42625175	104114303		CHEMBL477064				ZINC40917261	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225516	Brc1ccc2c(c1)[nH]c1c3[nH]c4ccccc4c3c3C(=O)NC(=O)c3c21	InChI=1S/C20H10BrN3O2/c21-8-5-6-10-12(7-8)23-18-14(10)16-15(19(25)24-20(16)26)13-9-3-1-2-4-11(9)22-17(13)18/h1-7,22-23H,(H,24,25,26)	NMFKDDRQSNVETB-UHFFFAOYSA-N	6860	6-bromo-3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaene-12,14-dione::Indolocarbazole deriv. 4(d)	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>20000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6860	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6860&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			5330797	8036429				5950		ZINC03991710	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225517	O\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2cc(Br)ccc12	InChI=1S/C16H10BrN3O2/c17-8-5-6-9-12(7-8)19-16(21)13(9)15-14(20-22)10-3-1-2-4-11(10)18-15/h1-7,18,22H,(H,19,21)/b15-13-,20-14+	DDLZLOKCJHBUHD-WAVHTBQISA-N	50012188	6BIO	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3500							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012188&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	BRW	1UV5	5287844	242058111			DB03444				3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225518	Nc1cc(Nc2ccc(cc2)S(N)(=O)=O)ncn1	InChI=1S/C10H11N5O2S/c11-9-5-10(14-6-13-9)15-7-1-3-8(4-2-7)18(12,16)17/h1-6H,(H2,12,16,17)(H3,11,13,14,15)	FVFVVRPJERUECT-UHFFFAOYSA-N	50503351	CHEMBL265964	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>20000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503351&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	U55	1JSV	2608	440711936							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225519	CC(C)c1cnc(NC(=O)Cc2ccccc2)s1	InChI=1S/C14H16N2OS/c1-10(2)12-9-15-14(18-12)16-13(17)8-11-6-4-3-5-7-11/h3-7,9-10H,8H2,1-2H3,(H,15,16,17)	IGRZXNLKVUEFDM-UHFFFAOYSA-N	50155210	CHEMBL426972::N-(5-Isopropyl-thiazol-2-yl)-2-phenyl-acetamide	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 637							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50155210	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50155210&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			16760027	104042714		CHEMBL426972				ZINC13827492	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225520	Nc1n[nH]c2nc3ccccc3nc12	InChI=1S/C9H7N5/c10-8-7-9(14-13-8)12-6-4-2-1-3-5(6)11-7/h1-4H,(H3,10,12,13,14)	DWHVZCLBMTZRQM-UHFFFAOYSA-N	7534	1H-pyrazolo[3,4-b]quinoxalin-3-amine::pyrazolo[3,4-b]quinoxaline deriv. 1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>20000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7534&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			438981	11108319				5947		ZINC05543794	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225554	CCOC(=O)c1cnc2oc3ccc(O)cc3c2c1-c1ccccc1	InChI=1S/C20H15NO4/c1-2-24-20(23)15-11-21-19-18(17(15)12-6-4-3-5-7-12)14-10-13(22)8-9-16(14)25-19/h3-11,22H,2H2,1H3	ZIAVUCXRGWKBBY-UHFFFAOYSA-N	50124027	6-Hydroxy-4-phenyl-benzo[4,5]furo[2,3-b]pyridine-3-carboxylic acid ethyl ester::CHEMBL132904::ethyl-(6-hydroxy-4-phenylbenzo[4,5]furo[2,3-b])pyridine-3-carboxylate	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>20000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50124027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50124027&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			403994	104016394		CHEMBL132904				ZINC01662929	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225555	COc1ccc2NC(=O)\C(=C/c3cnc[nH]3)c2c1	InChI=1S/C13H11N3O2/c1-18-9-2-3-12-10(5-9)11(13(17)16-12)4-8-6-14-7-15-8/h2-7H,1H3,(H,14,15)(H,16,17)/b11-4-	QNUKRWAIZMBVCU-WCIBSUBMSA-N	50503353	Su-9516	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 905							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503353&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			5289419	440711938							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225557	CC[C@H](CO)Nc1nc(Nc2cccc(c2)-c2ccccn2)c2ncn(C(C)C)c2n1	InChI=1S/C23H27N7O/c1-4-17(13-31)27-23-28-21(20-22(29-23)30(14-25-20)15(2)3)26-18-9-7-8-16(12-18)19-10-5-6-11-24-19/h5-12,14-15,17,31H,4,13H2,1-3H3,(H2,26,27,28,29)/t17-/m1/s1	LWANFAFTTOKZAX-QGZVFWFLSA-N	50244787	(R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phenylamino]-9-isopropylpurine::CHEMBL215919	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 822							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50244787	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50244787&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			25168304	104100717		CHEMBL215919				ZINC40979326	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225594	CC(=O)c1cnc2oc3ccc(O)cc3c2c1-c1ccccc1	InChI=1S/C19H13NO3/c1-11(21)15-10-20-19-18(17(15)12-5-3-2-4-6-12)14-9-13(22)7-8-16(14)23-19/h2-10,22H,1H3	RTDFHOPDAYJLII-UHFFFAOYSA-N	7451	1-{12-hydroxy-3-phenyl-8-oxa-6-azatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,5,9,11-hexaen-4-yl}ethan-1-one::3-Acetyl-6-hydroxy-4-phenylbenzo[4,5]furo[2,3-b]pyridine::CHEMBL133712::elbfluorene	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>20000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7451	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7451&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			403993	11108242		CHEMBL133712				ZINC01662928	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225595	CCN(CC)C(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1	InChI=1S/C23H30N6O2/c1-3-29(4-2)22(30)17-10-12-18(13-11-17)26-23-27-20-19(24-15-25-20)21(28-23)31-14-16-8-6-5-7-9-16/h10-13,15-16H,3-9,14H2,1-2H3,(H2,24,25,26,27,28)	XHEQSRJCJTWWAH-UHFFFAOYSA-N	50347924	CHEMBL1802728	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2300							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50347924	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50347924&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	AQG	5WIJ,8EX0,8B8N,6JGM	10202471	136354610		CHEMBL1802728		5949		ZINC22309248	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225596	CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1	InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)	UZWDCWONPYILKI-UHFFFAOYSA-N	50110183	Abemaciclib::LY-2835219::US10662186, Compound LY2835219::US10696678, Example LY2835219::US10988476, Compound LY2835219::US11053238, LY2835219::US11091476, Example LY2835219::US11351170, Example Abemaciclib	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3100							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110183&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	6ZV	7O7K,7O7J,5L2S,7SJ3	46220502	319493137							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225597	CCNc1cc(N[C@H]2CC[C@H](O)CC2)nc(Nc2ccc3n(Cc4ccccc4)ccc3c2)n1	InChI=1S/C27H32N6O/c1-2-28-25-17-26(29-21-8-11-23(34)12-9-21)32-27(31-25)30-22-10-13-24-20(16-22)14-15-33(24)18-19-6-4-3-5-7-19/h3-7,10,13-17,21,23,34H,2,8-9,11-12,18H2,1H3,(H3,28,29,30,31,32)/t21-,23-	YVXCDLCJCIDFHE-AFARHQOCSA-N	50503352	CGP82996::CHEMBL2028998	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50503352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50503352&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			24825971	440711937							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225598	OCCCNc1cc(ccn1)-c1ccnc(Nc2cccc(Cl)c2)n1	InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(12-14)23-18-22-9-6-16(24-18)13-5-8-21-17(11-13)20-7-2-10-25/h1,3-6,8-9,11-12,25H,2,7,10H2,(H,20,21)(H,22,23,24)	IYNDTACKOAXKBJ-UHFFFAOYSA-N	65549	3-[[4-[2-(3-chloroanilino)-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol::3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]-2-pyridyl]amino]propan-1-ol::3-[[4-[2-(3-chloroanilino)pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol::3-[[4-[2-[(3-chlorophenyl)amino]pyrimidin-4-yl]pyridin-2-yl]amino]propan-1-ol::MLS000911536::SMR000463552::cid_644215	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 200							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65549&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	8II	7S6V	644215	252644026						ZINC01541868	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225599	Cc1nc(N)sc1-c1ccnc(Nc2cccc(c2)[N+]([O-])=O)n1	InChI=1S/C14H12N6O2S/c1-8-12(23-13(15)17-8)11-5-6-16-14(19-11)18-9-3-2-4-10(7-9)20(21)22/h2-7H,1H3,(H2,15,17)(H,16,18,19)	DYTKVFHLKPDNRW-UHFFFAOYSA-N	50229973	(4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yl)-(3-nitrophenyl)amine::4-methyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)thiazol-2-amine::CHEMBL298445::[4-(2-AMINO-4-METHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-(3-NITRO-PHENYL)-AMINE	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 168							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50229973	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50229973&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	CK7	2WEV,1PXO,4B9D	447961	104098225		CHEMBL298445	DB02833			ZINC02047389	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225604	Nc1nc(Nc2ccc(cc2)S(N)(=O)=O)nn1C(=S)Nc1c(F)cccc1F	InChI=1S/C15H13F2N7O2S2/c16-10-2-1-3-11(17)12(10)21-15(27)24-13(18)22-14(23-24)20-8-4-6-9(7-5-8)28(19,25)26/h1-7H,(H,21,27)(H2,19,25,26)(H3,18,20,22,23)	ARIOBGGRZJITQX-UHFFFAOYSA-N	6878	1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3n::5-amino-N-(2,6-difluorophenyl)-3-[(4-sulfamoylphenyl)amino]-1H-1,2,4-triazole-1-carbothioamide	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 66							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6878&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	DKI	3LJ1,2CHL,4FZF,4AAA,2J51,3HMI,2JFL,4QMP,2W4O,2WU6	5330812	8036444			DB07664	5946		ZINC12355112	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225612	NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3nc[nH]c3n2)cc1	InChI=1S/C18H22N6O3S/c19-28(25,26)14-8-6-13(7-9-14)22-18-23-16-15(20-11-21-16)17(24-18)27-10-12-4-2-1-3-5-12/h6-9,11-12H,1-5,10H2,(H2,19,25,26)(H2,20,21,22,23,24)	OWXORKPNCHJYOF-UHFFFAOYSA-N	50235342	CHEMBL319467::NU-6102	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2500							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50235342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50235342&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	4SP	5M57,6BSS,2C6O,4EOK,4EOR,1H1S,5LQF,2IW8,2IW9	4566	384991216		CHEMBL319467					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225625	NS(=O)(=O)c1ccc(N\N=C2/C(=O)Nc3ccc(Br)cc23)cc1	InChI=1S/C14H11BrN4O3S/c15-8-1-6-12-11(7-8)13(14(20)17-12)19-18-9-2-4-10(5-3-9)23(16,21)22/h1-7,18H,(H2,16,21,22)(H,17,19,20)	ODZNNZYRBRRREX-UHFFFAOYSA-N	50202299	CHEMBL411491	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 19700							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50202299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50202299&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	106	1FVT	5858639	104081876		CHEMBL411491				ZINC29041603	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51225634	Cc1nc2c(s1)C(=O)C=C(Nc1ccc(C)cc1)C2=O	InChI=1S/C15H12N2O2S/c1-8-3-5-10(6-4-8)17-11-7-12(18)15-13(14(11)19)16-9(2)20-15/h3-7,17H,1-2H3	HFPLHASLIOXVGS-UHFFFAOYSA-N	50086655	2-Methyl-5-p-tolylamino-benzothiazole-4,7-dione::5-(N-(4-Methylphenyl)amino)-2-methyl-4,7-dioxobenzothiazole::CHEMBL290904	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>20000							ChEMBL	10.1021/acs.jmedchem.8b00049	10.7270/Q2FB5665	30234987			Jorda, R; Hendrychová, D; Voller, J; Řezníčková, E; Gucký, T; Kryštof, V	Palack£ University and Institute of Experimental Botany ASCR	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50086655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50086655&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			481747	103985840		CHEMBL290904		5952		ZINC05930916	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51267889	COc1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1	InChI=1S/C16H12O5/c1-20-15-12(19)7-10(17)14-11(18)8-13(21-16(14)15)9-5-3-2-4-6-9/h2-8,17,19H,1H3	XLTFNNCXVBYBSX-UHFFFAOYSA-N	50140257	5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one::5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one(Wogonin)::5,7-dihydroxy-8-methoxyflavone::CHEMBL16171::WOGONIN	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 12300							ChEMBL	10.1016/j.bmc.2019.01.027	10.7270/Q2CF9TG4	30733087			Zhao, L; Yuan, X; Wang, J; Feng, Y; Ji, F; Li, Z; Bian, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140257&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			5281703	104029877	10043	CHEMBL16171			C10197	ZINC00899093	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51272693	CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)occc3=O)c1	InChI=1S/C26H23N3O5/c1-29(2)20-8-6-17(7-9-20)26(32)28-19-5-3-4-18(14-19)27-25(31)16-34-21-10-11-22-23(30)12-13-33-24(22)15-21/h3-15H,16H2,1-2H3,(H,27,31)(H,28,32)	WVGDUQVQWLHVEA-UHFFFAOYSA-N	50519662	CHEMBL4438748	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.9b01143	10.7270/Q2MC93FG	31693351			Zhao, L; Li, Y; Wang, Y; Qiao, Z; Miao, Z; Yang, J; Huang, L; Tian, C; Li, L; Chen, D; Yang, S	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50519662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50519662&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			155513187	440728244							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51277957	CC[C@H](CO)Nc1nc(NCc2ccc(cc2)-c2ccccn2)c2ncn(C(C)C)c2n1	InChI=1S/C24H29N7O/c1-4-19(14-32)28-24-29-22(21-23(30-24)31(15-27-21)16(2)3)26-13-17-8-10-18(11-9-17)20-7-5-6-12-25-20/h5-12,15-16,19,32H,4,13-14H2,1-3H3,(H2,26,28,29,30)/t19-/m1/s1	HOCBJBNQIQQQGT-LJQANCHMSA-N	50154937	CHEMBL518800	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1769							ChEMBL	10.1021/acs.jmedchem.9b00189	10.7270/Q2G1647C	30943029			Jorda, R; Havlíček, L; Šturc, A; Tušková, D; Daumová, L; Alam, M; Škerlová, J; Nekardová, M; Peřina, M; Pospíšil, T; Široká, J; Urbánek, L; Pachl, P; Řezáčová, P; Strnad, M; Klener, P; Kryštof, V	Palack£ University and Institute of Experimental Botany	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50154937	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50154937&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	RC8	3DDP,6TD3	10224714	340133507		CHEMBL518800	DB08463				3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51277958	CCc1cnn2c(NCc3ccc[n+]([O-])c3)cc(nc12)N1CCCC[C@H]1CCO	InChI=1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,1H3/t18-/m0/s1	PIMQWRZWLQKKBJ-SFHVURJKSA-N	50139171	Dinaciclib::MK-7965::SCH-727965::US11643396, Example Dinaciclib	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 170							ChEMBL	10.1021/acs.jmedchem.9b00189	10.7270/Q2G1647C	30943029			Jorda, R; Havlíček, L; Šturc, A; Tušková, D; Daumová, L; Alam, M; Škerlová, J; Nekardová, M; Peřina, M; Pospíšil, T; Široká, J; Urbánek, L; Pachl, P; Řezáčová, P; Strnad, M; Klener, P; Kryštof, V	Palack£ University and Institute of Experimental Botany	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50139171	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50139171&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			46926350	336952252							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51277986	CC(C)c1n[nH]c2c(NCc3ccc(cc3)-c3ccccn3)nc(SCCN)nc12	InChI=1S/C22H25N7S/c1-14(2)18-19-20(29-28-18)21(27-22(26-19)30-12-10-23)25-13-15-6-8-16(9-7-15)17-5-3-4-11-24-17/h3-9,11,14H,10,12-13,23H2,1-2H3,(H,28,29)(H,25,26,27)	PCQPAKMJSYGXRE-UHFFFAOYSA-N	50521533	CHEMBL4540226	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 124							ChEMBL	10.1021/acs.jmedchem.9b00189	10.7270/Q2G1647C	30943029			Jorda, R; Havlíček, L; Šturc, A; Tušková, D; Daumová, L; Alam, M; Škerlová, J; Nekardová, M; Peřina, M; Pospíšil, T; Široká, J; Urbánek, L; Pachl, P; Řezáčová, P; Strnad, M; Klener, P; Kryštof, V	Palack£ University and Institute of Experimental Botany	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50521533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50521533&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138105941	440730115							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51288068	CCc1cccc(Nc2ncc3CCCCc3n2)c1	InChI=1S/C16H19N3/c1-2-12-6-5-8-14(10-12)18-16-17-11-13-7-3-4-9-15(13)19-16/h5-6,8,10-11H,2-4,7,9H2,1H3,(H,17,18,19)	BEUXLHXNNKSHIB-UHFFFAOYSA-N	50525158	CHEMBL4515564	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1021/acsmedchemlett.9b00029	10.7270/Q2X06BGP	31098000			Khair, NZ; Lenjisa, JL; Tadesse, S; Kumarasiri, M; Basnet, SKC; Mekonnen, LB; Li, M; Diab, S; Sykes, MJ; Albrecht, H; Milne, R; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50525158	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50525158&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			155539890	440733740							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51288100	NS(=O)(=O)c1cccc(Nc2ncc3CCCCc3n2)c1	InChI=1S/C14H16N4O2S/c15-21(19,20)12-6-3-5-11(8-12)17-14-16-9-10-4-1-2-7-13(10)18-14/h3,5-6,8-9H,1-2,4,7H2,(H2,15,19,20)(H,16,17,18)	ASNDURJGUUDPHG-UHFFFAOYSA-N	50525155	CHEMBL4561424	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1021/acsmedchemlett.9b00029	10.7270/Q2X06BGP	31098000			Khair, NZ; Lenjisa, JL; Tadesse, S; Kumarasiri, M; Basnet, SKC; Mekonnen, LB; Li, M; Diab, S; Sykes, MJ; Albrecht, H; Milne, R; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50525155	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50525155&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			155559110	440733737							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51288101	COc1cccc(Nc2ncc3CCCCc3n2)c1	InChI=1S/C15H17N3O/c1-19-13-7-4-6-12(9-13)17-15-16-10-11-5-2-3-8-14(11)18-15/h4,6-7,9-10H,2-3,5,8H2,1H3,(H,16,17,18)	DYNWEDRLLZIBOF-UHFFFAOYSA-N	50525157	CHEMBL4460155	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1021/acsmedchemlett.9b00029	10.7270/Q2X06BGP	31098000			Khair, NZ; Lenjisa, JL; Tadesse, S; Kumarasiri, M; Basnet, SKC; Mekonnen, LB; Li, M; Diab, S; Sykes, MJ; Albrecht, H; Milne, R; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50525157	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50525157&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			155527932	440733739							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51288102	Cc1ccccc1Nc1ncc2CCCCc2n1	InChI=1S/C15H17N3/c1-11-6-2-4-8-13(11)17-15-16-10-12-7-3-5-9-14(12)18-15/h2,4,6,8,10H,3,5,7,9H2,1H3,(H,16,17,18)	GXNCJJUXJCUZSD-UHFFFAOYSA-N	50525160	CHEMBL4522230	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1021/acsmedchemlett.9b00029	10.7270/Q2X06BGP	31098000			Khair, NZ; Lenjisa, JL; Tadesse, S; Kumarasiri, M; Basnet, SKC; Mekonnen, LB; Li, M; Diab, S; Sykes, MJ; Albrecht, H; Milne, R; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50525160	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50525160&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			155543060	440733742							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51288103	Cc1ccc(Nc2ncc3CCCCc3n2)cc1	InChI=1S/C15H17N3/c1-11-6-8-13(9-7-11)17-15-16-10-12-4-2-3-5-14(12)18-15/h6-10H,2-5H2,1H3,(H,16,17,18)	DQBAQLBXYGRJMA-UHFFFAOYSA-N	50525161	CHEMBL4557901	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1021/acsmedchemlett.9b00029	10.7270/Q2X06BGP	31098000			Khair, NZ; Lenjisa, JL; Tadesse, S; Kumarasiri, M; Basnet, SKC; Mekonnen, LB; Li, M; Diab, S; Sykes, MJ; Albrecht, H; Milne, R; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50525161	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50525161&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			66493692	440733743							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51288121	[O-][N+](=O)c1cccc(Nc2ncc3CCCCc3n2)c1	InChI=1S/C14H14N4O2/c19-18(20)12-6-3-5-11(8-12)16-14-15-9-10-4-1-2-7-13(10)17-14/h3,5-6,8-9H,1-2,4,7H2,(H,15,16,17)	IDELUCHFZTYRPZ-UHFFFAOYSA-N	50525159	CHEMBL4471293	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1021/acsmedchemlett.9b00029	10.7270/Q2X06BGP	31098000			Khair, NZ; Lenjisa, JL; Tadesse, S; Kumarasiri, M; Basnet, SKC; Mekonnen, LB; Li, M; Diab, S; Sykes, MJ; Albrecht, H; Milne, R; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50525159	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50525159&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			155534846	440733741							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51288126	Cc1cccc(Nc2ncc3CCCCc3n2)c1	InChI=1S/C15H17N3/c1-11-5-4-7-13(9-11)17-15-16-10-12-6-2-3-8-14(12)18-15/h4-5,7,9-10H,2-3,6,8H2,1H3,(H,16,17,18)	IPZUHNOYKQXXBS-UHFFFAOYSA-N	50525156	CHEMBL4476248	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1021/acsmedchemlett.9b00029	10.7270/Q2X06BGP	31098000			Khair, NZ; Lenjisa, JL; Tadesse, S; Kumarasiri, M; Basnet, SKC; Mekonnen, LB; Li, M; Diab, S; Sykes, MJ; Albrecht, H; Milne, R; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50525156	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50525156&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			155538384	440733738							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51310750	CC(C1CC1)n1cnc2c(NCc3cccc(c3)C(F)(F)F)nc(NCCN(C)C)nc12	InChI=1S/C22H28F3N7/c1-14(16-7-8-16)32-13-28-18-19(29-21(30-20(18)32)26-9-10-31(2)3)27-12-15-5-4-6-17(11-15)22(23,24)25/h4-6,11,13-14,16H,7-10,12H2,1-3H3,(H2,26,27,29,30)	GHRNSZVMIARHIS-UHFFFAOYSA-N	50531923	CHEMBL4462126	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2400							ChEMBL	10.1021/acs.jmedchem.8b01541	10.7270/Q2833WHR	30707835			Lee, JW; Hirota, T; Ono, D; Honma, S; Honma, KI; Park, K; Kay, SA	Korea Institute of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50531923	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50531923&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138403252	440740505							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51310755	CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1	InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1	BTIHMVBBUGXLCJ-OAHLLOKOSA-N	7533	(2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]amino]butan-1-ol::(2R)-2-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]butan-1-ol::(2R)-2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-2-purinyl]amino]-1-butanol::(2R)-2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol::(2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol::(R)-Roscovitine::2,6,9-Trisubstituted purine deriv. 28::CHEMBL14762::CYC-202::Roscovitine::cid_160355	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2200							ChEMBL	10.1021/acs.jmedchem.8b01541	10.7270/Q2833WHR	30707835			Lee, JW; Hirota, T; Ono, D; Honma, S; Honma, KI; Park, K; Kay, SA	Korea Institute of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7533&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	RRC	3DDQ,1YGK,2A4L,1UNL	160355	11108321		CHEMBL14762		6035		ZINC01649340	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51310759	CC(C)n1cnc2c(NCc3cccc(c3)C(F)(F)F)ncnc12	InChI=1S/C16H16F3N5/c1-10(2)24-9-23-13-14(21-8-22-15(13)24)20-7-11-4-3-5-12(6-11)16(17,18)19/h3-6,8-10H,7H2,1-2H3,(H,20,21,22)	REKSFCCYDQMSIN-UHFFFAOYSA-N	50531922	CHEMBL4471178	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 32000							ChEMBL	10.1021/acs.jmedchem.8b01541	10.7270/Q2833WHR	30707835			Lee, JW; Hirota, T; Ono, D; Honma, S; Honma, KI; Park, K; Kay, SA	Korea Institute of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50531922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50531922&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			49830252	440740504							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297375	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H34ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-4,6,9-15,18-19,22-23,33H,5,7-8,16-17H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+/t22-,23+/m0/s1	DLISTLYUFVETPG-YPCZXWAUSA-N	50528811	CHEMBL4441405	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 105								ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528811&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91754660	440737393							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297378	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)[nH]nc2C1(C)C)c1ccccc1	InChI=1S/C28H33N7O3/c1-6-23(36)29-20-14-12-19(13-15-20)26(37)31-25-21-16-35(28(2,3)24(21)32-33-25)27(38)30-22(17-34(4)5)18-10-8-7-9-11-18/h6-15,22H,1,16-17H2,2-5H3,(H,29,36)(H,30,38)(H2,31,32,33,37)/t22-/m1/s1	KPABJHHKKJIDGX-JOCHJYFZSA-N	50526795	CHEMBL4450322	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 53							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526795&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			121443990	440735377							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297380	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1	InChI=1S/C31H28ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-15,17-19,33H,16H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+	OBJNFLYHUXWUPF-IZZDOVSWSA-N	50110178	CHEMBL3603847::US10787436, Compound I-23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110178&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			73602827	319493132		CHEMBL3603847					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297381	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1	InChI=1S/C31H28ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-15,17-19,33H,16H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+	OBJNFLYHUXWUPF-IZZDOVSWSA-N	50110178	CHEMBL3603847::US10787436, Compound I-23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 421							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110178&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			73602827	319493132		CHEMBL3603847					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297384	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1	InChI=1S/C31H28ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-15,17-19,33H,16H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+	OBJNFLYHUXWUPF-IZZDOVSWSA-N	50110178	CHEMBL3603847::US10787436, Compound I-23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 238							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110178&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			73602827	319493132		CHEMBL3603847					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297385	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1	InChI=1S/C31H28ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-15,17-19,33H,16H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+	OBJNFLYHUXWUPF-IZZDOVSWSA-N	50110178	CHEMBL3603847::US10787436, Compound I-23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens				 10.0					ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110178&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			73602827	319493132		CHEMBL3603847					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297386	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C30H33ClN8O2/c1-39(2)14-6-11-27(40)35-21-12-13-26(32-16-21)29(41)36-19-7-5-8-20(15-19)37-30-34-18-24(31)28(38-30)23-17-33-25-10-4-3-9-22(23)25/h3-4,6,9-13,16-20,33H,5,7-8,14-15H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+/t19-,20+/m0/s1	WFWFIAFTMSUDNO-CHUTXNTCSA-N	50528814	CHEMBL4436535	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 205							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528814&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91938075	440737396							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297388	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C30H33ClN8O2/c1-39(2)14-6-11-27(40)35-21-12-13-26(32-16-21)29(41)36-19-7-5-8-20(15-19)37-30-34-18-24(31)28(38-30)23-17-33-25-10-4-3-9-22(23)25/h3-4,6,9-13,16-20,33H,5,7-8,14-15H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+/t19-,20+/m0/s1	WFWFIAFTMSUDNO-CHUTXNTCSA-N	50528814	CHEMBL4436535	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens				 4.0					ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528814&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91938075	440737396							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297389	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H34ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-4,6,9-15,18-19,22-23,33H,5,7-8,16-17H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+/t22-,23+/m0/s1	DLISTLYUFVETPG-YPCZXWAUSA-N	50528811	CHEMBL4441405	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 908							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528811&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91754660	440737393							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297392	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@@]1(C)CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H35ClN8O2/c1-31(39-29(42)26-13-12-21(17-33-26)36-27(41)11-7-15-40(2)3)14-6-8-20(16-31)37-30-35-19-24(32)28(38-30)23-18-34-25-10-5-4-9-22(23)25/h4-5,7,9-13,17-20,34H,6,8,14-16H2,1-3H3,(H,36,41)(H,39,42)(H,35,37,38)/b11-7+/t20-,31+/m1/s1	SCJNYBYSTCRPAO-LXBQGUBHSA-N	50528812	CHEMBL4582951	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 17								ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528812&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118426108	440737394							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297393	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@@]1(C)CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H35ClN8O2/c1-31(39-29(42)26-13-12-21(17-33-26)36-27(41)11-7-15-40(2)3)14-6-8-20(16-31)37-30-35-19-24(32)28(38-30)23-18-34-25-10-5-4-9-22(23)25/h4-5,7,9-13,17-20,34H,6,8,14-16H2,1-3H3,(H,36,41)(H,39,42)(H,35,37,38)/b11-7+/t20-,31+/m1/s1	SCJNYBYSTCRPAO-LXBQGUBHSA-N	50528812	CHEMBL4582951	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens				 13					ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528812&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118426108	440737394							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297405	CCc1cnn2c(Nc3cccc(NC(=O)C=C)c3)cc(nc12)N1CCCC[C@H]1CCO	InChI=1S/C24H30N6O2/c1-3-17-16-25-30-22(26-18-8-7-9-19(14-18)27-23(32)4-2)15-21(28-24(17)30)29-12-6-5-10-20(29)11-13-31/h4,7-9,14-16,20,26,31H,2-3,5-6,10-13H2,1H3,(H,27,32)/t20-/m0/s1	CDCHESFKYUNJPV-FQEVSTJZSA-N	50528815	CHEMBL4468670	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1200							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528815&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122596923	440737397							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297418	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1	InChI=1S/C31H28ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-15,17-19,33H,16H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+	OBJNFLYHUXWUPF-IZZDOVSWSA-N	50110178	CHEMBL3603847::US10787436, Compound I-23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 255								ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110178&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			73602827	319493132		CHEMBL3603847					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297423	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@@]1(C)CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H35ClN8O2/c1-31(39-29(42)26-13-12-21(17-33-26)36-27(41)11-7-15-40(2)3)14-6-8-20(16-31)37-30-35-19-24(32)28(38-30)23-18-34-25-10-5-4-9-22(23)25/h4-5,7,9-13,17-20,34H,6,8,14-16H2,1-3H3,(H,36,41)(H,39,42)(H,35,37,38)/b11-7+/t20-,31+/m1/s1	SCJNYBYSTCRPAO-LXBQGUBHSA-N	50528812	CHEMBL4582951	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 84							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528812&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118426108	440737394							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297424	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C30H32ClN7O2/c1-37(2)15-6-10-27(39)34-21-13-11-20(12-14-21)29(40)38-16-5-7-22(19-38)35-30-33-18-25(31)28(36-30)24-17-32-26-9-4-3-8-23(24)26/h3-4,6,8-14,17-18,22,32H,5,7,15-16,19H2,1-2H3,(H,34,39)(H,33,35,36)/b10-6+/t22-/m1/s1	RUBYHLPRZRMTJO-MOVYNIQHSA-N	50528813	CHEMBL4163879	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8500							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528813	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528813&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118025540	440737395							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297425	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C30H33ClN8O2/c1-39(2)14-6-11-27(40)35-21-12-13-26(32-16-21)29(41)36-19-7-5-8-20(15-19)37-30-34-18-24(31)28(38-30)23-17-33-25-10-4-3-9-22(23)25/h3-4,6,9-13,16-20,33H,5,7-8,14-15H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+/t19-,20+/m0/s1	WFWFIAFTMSUDNO-CHUTXNTCSA-N	50528814	CHEMBL4436535	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 23							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528814&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91938075	440737396							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297426	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H34ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-4,6,9-15,18-19,22-23,33H,5,7-8,16-17H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+/t22-,23+/m0/s1	DLISTLYUFVETPG-YPCZXWAUSA-N	50528811	CHEMBL4441405	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens				 48					ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528811&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91754660	440737393							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297430	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@@]1(C)CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H35ClN8O2/c1-31(39-29(42)26-13-12-21(17-33-26)36-27(41)11-7-15-40(2)3)14-6-8-20(16-31)37-30-35-19-24(32)28(38-30)23-18-34-25-10-5-4-9-22(23)25/h4-5,7,9-13,17-20,34H,6,8,14-16H2,1-3H3,(H,36,41)(H,39,42)(H,35,37,38)/b11-7+/t20-,31+/m1/s1	SCJNYBYSTCRPAO-LXBQGUBHSA-N	50528812	CHEMBL4582951	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 590							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528812&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118426108	440737394							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297447	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H34ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-4,6,9-15,18-19,22-23,33H,5,7-8,16-17H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+/t22-,23+/m0/s1	DLISTLYUFVETPG-YPCZXWAUSA-N	50528811	CHEMBL4441405	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 112							ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528811&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91754660	440737393							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51297448	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C30H33ClN8O2/c1-39(2)14-6-11-27(40)35-21-12-13-26(32-16-21)29(41)36-19-7-5-8-20(15-19)37-30-34-18-24(31)28(38-30)23-17-33-25-10-4-3-9-22(23)25/h3-4,6,9-13,16-20,33H,5,7-8,14-15H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+/t19-,20+/m0/s1	WFWFIAFTMSUDNO-CHUTXNTCSA-N	50528814	CHEMBL4436535	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 63								ChEMBL	10.1016/j.bmcl.2019.126637	10.7270/Q23F4T3T	31477350			Sánchez-Martínez, C; Lallena, MJ; Sanfeliciano, SG; de Dios, A	Eli Lilly and Company	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528814&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91938075	440737396							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51292318	CC(C)c1cnn2c(NCc3ccccc3)cc(NC[C@]3(O)CCNC[C@H]3O)nc12	InChI=1S/C22H30N6O2/c1-15(2)17-12-26-28-20(24-11-16-6-4-3-5-7-16)10-19(27-21(17)28)25-14-22(30)8-9-23-13-18(22)29/h3-7,10,12,15,18,23-24,29-30H,8-9,11,13-14H2,1-2H3,(H,25,27)/t18-,22-/m1/s1	OVDMCYNLHNMECD-XMSQKQJNSA-N	50526788	CHEMBL4471850	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 18							ChEMBL	10.1016/j.ejmech.2019.111641	10.7270/Q24X5C86	31514062			Teng, Y; Lu, K; Zhang, Q; Zhao, L; Huang, Y; Ingarra, AM; Galons, H; Li, T; Cui, S; Yu, P; Oumata, N	Tianjin University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526788	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526788&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118329742	440735370							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51292320	CC(C)c1cnn2c(NCc3ccccc3)cc(NC[C@@H]3CCNC[C@H]3O)nc12	InChI=1S/C22H30N6O/c1-15(2)18-13-26-28-21(25-11-16-6-4-3-5-7-16)10-20(27-22(18)28)24-12-17-8-9-23-14-19(17)29/h3-7,10,13,15,17,19,23,25,29H,8-9,11-12,14H2,1-2H3,(H,24,27)/t17-,19+/m0/s1	YCVGLKWJKIKVBI-PKOBYXMFSA-N	50526789	CHEMBL4459754	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 41							ChEMBL	10.1016/j.ejmech.2019.111641	10.7270/Q24X5C86	31514062			Teng, Y; Lu, K; Zhang, Q; Zhao, L; Huang, Y; Ingarra, AM; Galons, H; Li, T; Cui, S; Yu, P; Oumata, N	Tianjin University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526789	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526789&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	I73	5JQ8	137349544	440735371							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51292369	CC(C)c1cnn2c(NCc3ccccc3)cc(NCC3CCNCC3)nc12	InChI=1S/C22H30N6/c1-16(2)19-15-26-28-21(25-14-17-6-4-3-5-7-17)12-20(27-22(19)28)24-13-18-8-10-23-11-9-18/h3-7,12,15-16,18,23,25H,8-11,13-14H2,1-2H3,(H,24,27)	JKCBZAYPKOXUKH-UHFFFAOYSA-N	50526805	CHEMBL4519886	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 310							ChEMBL	10.1016/j.ejmech.2019.111641	10.7270/Q24X5C86	31514062			Teng, Y; Lu, K; Zhang, Q; Zhao, L; Huang, Y; Ingarra, AM; Galons, H; Li, T; Cui, S; Yu, P; Oumata, N	Tianjin University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526805&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118329761	440735387							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51292376	CC(C)c1cnn2c(NCc3ccccc3)cc(NC[C@]3(CO)CCNC3)nc12	InChI=1S/C22H30N6O/c1-16(2)18-12-26-28-20(24-11-17-6-4-3-5-7-17)10-19(27-21(18)28)25-14-22(15-29)8-9-23-13-22/h3-7,10,12,16,23-24,29H,8-9,11,13-15H2,1-2H3,(H,25,27)/t22-/m0/s1	AUZGEDPWRMYCLE-QFIPXVFZSA-N	50526804	CHEMBL4553241	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 14							ChEMBL	10.1016/j.ejmech.2019.111641	10.7270/Q24X5C86	31514062			Teng, Y; Lu, K; Zhang, Q; Zhao, L; Huang, Y; Ingarra, AM; Galons, H; Li, T; Cui, S; Yu, P; Oumata, N	Tianjin University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526804	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526804&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			155555568	440735386							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51292379	CC(C)c1cnn2c(NCc3ccccc3)cc(NC[C@H]3CCCC[C@@H]3O)nc12	InChI=1S/C23H31N5O/c1-16(2)19-15-26-28-22(25-13-17-8-4-3-5-9-17)12-21(27-23(19)28)24-14-18-10-6-7-11-20(18)29/h3-5,8-9,12,15-16,18,20,25,29H,6-7,10-11,13-14H2,1-2H3,(H,24,27)/t18-,20+/m1/s1	FEWLFECITKFLDY-QUCCMNQESA-N	50526796	CHEMBL4472515	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 687							ChEMBL	10.1016/j.ejmech.2019.111641	10.7270/Q24X5C86	31514062			Teng, Y; Lu, K; Zhang, Q; Zhao, L; Huang, Y; Ingarra, AM; Galons, H; Li, T; Cui, S; Yu, P; Oumata, N	Tianjin University of Science and Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526796&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118329760	440735378							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
979484	CN1CCN(CC1)c1ccc(Nc2ncc3C(=O)CC4N(c3n2)C(C)(C)CNC4=O)nc1	InChI=1S/C22H28N8O2/c1-22(2)13-25-20(32)16-10-17(31)15-12-24-21(27-19(15)30(16)22)26-18-5-4-14(11-23-18)29-8-6-28(3)7-9-29/h4-5,11-12,16H,6-10,13H2,1-3H3,(H,25,32)(H,23,24,26,27)	UNHLUCCQTMZQPA-UHFFFAOYSA-N	472673	10,10-dimethyl-2-((5-(4- methylpiperazin-1-yl)pyridin-2- yl)amino)-6,6a,9,10-tetrahydro- 5H-pyrazino[1',2':1,6]pyrido[2,3- d]pyrimidine-5,7(8H)-dione::US10829490, Cmpd # 1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q20V8GV8		aid1805008	US10829490	Strum, JC; Jung, D	GI Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=472673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=472673&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91971970	441611658							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
979489	CN1CCN(CC1)c1ccc(Nc2ncc3C(=O)CC4N(c3n2)C2(CCCCC2)CNC4=O)nc1	InChI=1S/C25H32N8O2/c1-31-9-11-32(12-10-31)17-5-6-21(26-14-17)29-24-27-15-18-20(34)13-19-23(35)28-16-25(7-3-2-4-8-25)33(19)22(18)30-24/h5-6,14-15,19H,2-4,7-13,16H2,1H3,(H,28,35)(H,26,27,29,30)	ZUEUXHMSDWCNAD-UHFFFAOYSA-N	472675	2'-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino)-6',6a',8',9'- tetrahydrospiro[cyclohexane-1,10'- pyrazino[1',2':1,6]pyrido[2,3- d]pyrimidine1-5',7'-dione::US10829490, Cmpd # 3	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q20V8GV8		aid1805008	US10829490	Strum, JC; Jung, D	GI Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=472675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=472675&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118451261	441611660							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
979492	CN1CCN(CC1)c1ccc(Nc2ncc3CCC4N(c3n2)C2(CCCCC2)CNC4=O)nc1	InChI=1S/C25H34N8O/c1-31-11-13-32(14-12-31)19-6-8-21(26-16-19)29-24-27-15-18-5-7-20-23(34)28-17-25(9-3-2-4-10-25)33(20)22(18)30-24/h6,8,15-16,20H,2-5,7,9-14,17H2,1H3,(H,28,34)(H,26,27,29,30)	RNYWSMGOKRDBKS-UHFFFAOYSA-N	472677	2'-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino)-6',6a',8',9'- tetrahydrospiro[cyclohexane-1,10'- pyrazino[1',2':1,6]pyrido[2,3- d]pyrimidin]-7'(5'H)-one::US10829490, Cmpd # 4	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q20V8GV8		aid1805008	US10829490	Strum, JC; Jung, D	GI Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=472677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=472677&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118451266	441611662							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
979495	CN1CCN(CC1)c1ccc(Nc2ncc3C(=O)CC4N(c3n2)C2(CCCC2)CNC4=O)nc1	InChI=1S/C24H30N8O2/c1-30-8-10-31(11-9-30)16-4-5-20(25-13-16)28-23-26-14-17-19(33)12-18-22(34)27-15-24(6-2-3-7-24)32(18)21(17)29-23/h4-5,13-14,18H,2-3,6-12,15H2,1H3,(H,27,34)(H,25,26,28,29)	NSDIQCPIAXVCSR-UHFFFAOYSA-N	472678	2'-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino)-6',6a',8',9'- tetrahydrospiro[cyclopentane- 1,10'- pyrazino[1',2':1,6]pyrido[2,3- d]pyrimidine]-5',7'-dione::US10829490, Cmpd # 5	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q20V8GV8		aid1805008	US10829490	Strum, JC; Jung, D	GI Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=472678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=472678&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118451284	441611663							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
979498	CN1CCN(CC1)c1ccc(Nc2ncc3C(=O)CC4N(CCNC4=O)c3n2)nc1	InChI=1S/C20H24N8O2/c1-26-6-8-27(9-7-26)13-2-3-17(22-11-13)24-20-23-12-14-16(29)10-15-19(30)21-4-5-28(15)18(14)25-20/h2-3,11-12,15H,4-10H2,1H3,(H,21,30)(H,22,23,24,25)	DZTLZHYVLZLORI-UHFFFAOYSA-N	472680	2-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino)-6,6a,9,10- tetrahydro-5H- pyrazino[1',2':1,6]pyrido[2,3- d]pyrimidine-5,7(8H)-dione::US10829490, Cmpd # 6	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q20V8GV8		aid1805008	US10829490	Strum, JC; Jung, D	GI Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=472680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=472680&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118451280	441611665							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
979501	CN1CCN(CC1)c1ccc(Nc2ncc3C(=O)CC4CCCCN4c3n2)nc1	InChI=1S/C21H27N7O/c1-26-8-10-27(11-9-26)16-5-6-19(22-13-16)24-21-23-14-17-18(29)12-15-4-2-3-7-28(15)20(17)25-21/h5-6,13-15H,2-4,7-12H2,1H3,(H,22,23,24,25)	MPKVXUVEJFYHOA-UHFFFAOYSA-N	472681	2-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino)- 6,6a,7,8,9,10-hexahydro-5H- pyrimido[5,4-c]quinolizin-5-one::US10829490, Cmpd # 7	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q20V8GV8		aid1805008	US10829490	Strum, JC; Jung, D	GI Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=472681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=472681&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138598470	441611666							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
979504	CCOC(=O)C1C2CCCCN2c2nc(Nc3ccc(cn3)N3CCN(C)CC3)ncc2C1=O	InChI=1S/C24H31N7O3/c1-3-34-23(33)20-18-6-4-5-9-31(18)22-17(21(20)32)15-26-24(28-22)27-19-8-7-16(14-25-19)30-12-10-29(2)11-13-30/h7-8,14-15,18,20H,3-6,9-13H2,1-2H3,(H,25,26,27,28)	CEMBQCFJEVCGEW-UHFFFAOYSA-N	472682	US10829490, Cmpd # 8::ethyl 2-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino)-5-oxo- 6,6a,7,8,9,10-hexahydro-5H- pyrimido[5,4-c]quinolizine-6- carboxylate	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q20V8GV8		aid1805008	US10829490	Strum, JC; Jung, D	GI Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=472682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=472682&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138598469	441611667							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
979507	CN1CCN(CC1)c1ccc(Nc2ncc3C=CC4=NCCC5(CCCCC5)N4c3n2)nc1	InChI=1S/C25H32N8/c1-31-13-15-32(16-14-31)20-6-7-21(27-18-20)29-24-28-17-19-5-8-22-26-12-11-25(9-3-2-4-10-25)33(22)23(19)30-24/h5-8,17-18H,2-4,9-16H2,1H3,(H,27,28,29,30)	IQXZJADJLYZGSK-UHFFFAOYSA-N	472683	N-(5-(4-methylpiperazin-1- yl)pyridin-2-yl)-8',9'- dihydrospiro[cyclohexane-1,10'- pyrido[1,6-a:2,3-d']dipyrimidin]- 2'-amine::US10829490, Cmpd # 9	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							US Patent		10.7270/Q20V8GV8		aid1805008	US10829490	Strum, JC; Jung, D	GI Therapeutics, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=472683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=472683&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138598456	441611668							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333158	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H34ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-4,6,9-15,18-19,22-23,33H,5,7-8,16-17H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+/t22-,23+/m0/s1	DLISTLYUFVETPG-YPCZXWAUSA-N	50528811	CHEMBL4441405	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 112							ChEMBL	10.1021/acs.jmedchem.9b01985	10.7270/Q2C82DT8	32150405			Diab, S; Yu, M; Wang, S	Lebanese American University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528811&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91754660	440737393							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333164	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C30H32ClN7O2/c1-37(2)15-6-10-27(39)34-21-13-11-20(12-14-21)29(40)38-16-5-7-22(19-38)35-30-33-18-25(31)28(36-30)24-17-32-26-9-4-3-8-23(24)26/h3-4,6,8-14,17-18,22,32H,5,7,15-16,19H2,1-2H3,(H,34,39)(H,33,35,36)/b10-6+/t22-/m1/s1	RUBYHLPRZRMTJO-MOVYNIQHSA-N	50528813	CHEMBL4163879	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8500							ChEMBL	10.1021/acs.jmedchem.9b01985	10.7270/Q2C82DT8	32150405			Diab, S; Yu, M; Wang, S	Lebanese American University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528813	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528813&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118025540	440737395							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333165	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@@]1(C)CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H35ClN8O2/c1-31(39-29(42)26-13-12-21(17-33-26)36-27(41)11-7-15-40(2)3)14-6-8-20(16-31)37-30-35-19-24(32)28(38-30)23-18-34-25-10-5-4-9-22(23)25/h4-5,7,9-13,17-20,34H,6,8,14-16H2,1-3H3,(H,36,41)(H,39,42)(H,35,37,38)/b11-7+/t20-,31+/m1/s1	SCJNYBYSTCRPAO-LXBQGUBHSA-N	50528812	CHEMBL4582951	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 84							ChEMBL	10.1021/acs.jmedchem.9b01985	10.7270/Q2C82DT8	32150405			Diab, S; Yu, M; Wang, S	Lebanese American University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528812&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118426108	440737394							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333166	CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3cccc(NC(=O)c4ccc(NC(=O)C=C)cc4)c3)n[nH]c2C1(C)C)c1ccccc1	InChI=1S/C34H38N8O3/c1-6-29(43)35-24-17-15-23(16-18-24)32(44)37-26-14-10-13-25(19-26)36-31-27-20-42(34(2,3)30(27)39-40-31)33(45)38-28(21-41(4)5)22-11-8-7-9-12-22/h6-19,28H,1,20-21H2,2-5H3,(H,35,43)(H,37,44)(H,38,45)(H2,36,39,40)/t28-/m1/s1	VBYGXNURPHQSPG-MUUNZHRXSA-N	50526803	CHEMBL4434871::US10870651, Compound 101	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 7.6							ChEMBL	10.1021/acs.jmedchem.9b01985	10.7270/Q2C82DT8	32150405			Diab, S; Yu, M; Wang, S	Lebanese American University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526803&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			121444083	440735385							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333169	CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3nc(C)nc4ccsc34)[nH]nc2C1(C)C)c1ccccc1	InChI=1S/C25H30N8OS/c1-15-26-18-11-12-35-20(18)23(27-15)29-22-17-13-33(25(2,3)21(17)30-31-22)24(34)28-19(14-32(4)5)16-9-7-6-8-10-16/h6-12,19H,13-14H2,1-5H3,(H,28,34)(H2,26,27,29,30,31)/t19-/m1/s1	AYCPARAPKDAOEN-LJQANCHMSA-N	101536	CHEMBL3128043::US8530494, 203::US8530652, 114::US8530652, 63	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 7.0							ChEMBL	10.1021/acs.jmedchem.9b01985	10.7270/Q2C82DT8	32150405			Diab, S; Yu, M; Wang, S	Lebanese American University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=101536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=101536&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			25227462	165223913		CHEMBL3128043				ZINC96172491	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333175	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C30H33ClN8O2/c1-39(2)14-6-11-27(40)35-21-12-13-26(32-16-21)29(41)36-19-7-5-8-20(15-19)37-30-34-18-24(31)28(38-30)23-17-33-25-10-4-3-9-22(23)25/h3-4,6,9-13,16-20,33H,5,7-8,14-15H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+/t19-,20+/m0/s1	WFWFIAFTMSUDNO-CHUTXNTCSA-N	50528814	CHEMBL4436535	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 23							ChEMBL	10.1021/acs.jmedchem.9b01985	10.7270/Q2C82DT8	32150405			Diab, S; Yu, M; Wang, S	Lebanese American University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528814&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91938075	440737396							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333177	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1	InChI=1S/C31H28ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-15,17-19,33H,16H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b11-6+	OBJNFLYHUXWUPF-IZZDOVSWSA-N	50110178	CHEMBL3603847::US10787436, Compound I-23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 238							ChEMBL	10.1021/acs.jmedchem.9b01985	10.7270/Q2C82DT8	32150405			Diab, S; Yu, M; Wang, S	Lebanese American University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110178&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			73602827	319493132		CHEMBL3603847					3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333180	CN(C)C\C=C\C(=O)Nc1cccc(c1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1	InChI=1S/C31H28ClN7O2/c1-39(2)15-7-14-28(40)35-21-9-5-8-20(16-21)30(41)36-22-10-6-11-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-13-4-3-12-24(25)27/h3-14,16-19,33H,15H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)/b14-7+	FONRCZUZCHXWBD-VGOFMYFVSA-N	50526794	CHEMBL4303287::US10787436, Compound I-18	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 14							ChEMBL	10.1021/acs.jmedchem.9b01985	10.7270/Q2C82DT8	32150405			Diab, S; Yu, M; Wang, S	Lebanese American University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526794	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526794&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			78357763	440735376							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333183	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)[nH]nc2C1(C)C)c1ccccc1	InChI=1S/C28H33N7O3/c1-6-23(36)29-20-14-12-19(13-15-20)26(37)31-25-21-16-35(28(2,3)24(21)32-33-25)27(38)30-22(17-34(4)5)18-10-8-7-9-11-18/h6-15,22H,1,16-17H2,2-5H3,(H,29,36)(H,30,38)(H2,31,32,33,37)/t22-/m1/s1	KPABJHHKKJIDGX-JOCHJYFZSA-N	50526795	CHEMBL4450322	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.7							ChEMBL	10.1021/acs.jmedchem.9b01985	10.7270/Q2C82DT8	32150405			Diab, S; Yu, M; Wang, S	Lebanese American University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526795&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			121443990	440735377							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
50831667	C[C@@H]1C[C@H]1C(=O)N1CCN(C[C@H]1C)c1cnc(C#N)c(n1)-c1cnn(C)c1	InChI=1S/C19H23N7O/c1-12-6-15(12)19(27)26-5-4-25(10-13(26)2)17-9-21-16(7-20)18(23-17)14-8-22-24(3)11-14/h8-9,11-13,15H,4-6,10H2,1-3H3/t12-,13-,15-/m1/s1	GXEXIUKEWXZCEF-UMVBOHGHSA-N	50537742	CHEMBL4634634::US11179389, Compound 1-14	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2019.126715	10.7270/Q2HM5CZG	31757666			Zhou, H; McGowan, MA; Lipford, K; Christopher, M; Fradera, X; Witter, D; Lesburg, CA; Li, C; Methot, JL; Lampe, J; Achab, A; Shaffer, L; Goldenblatt, P; Shah, S; Bass, A; Schroeder, G; Chen, D; Zeng, H; Augustin, MA; Katz, JD	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50537742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50537742&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	5D 	6OCU	145704650	442139305							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333877	CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1	InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)	OUSFTKFNBAZUKL-UHFFFAOYSA-N	5931	BMS-387072::CHEMBL296468::N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide::N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide::cid_3025986	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 184							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5931&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	56H	5D1J	3025986	8035540		CHEMBL296468		5670		ZINC03816409	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333878	CC(C)(C)c1cnc(CSc2cnc(NC(=O)c3cccc(NC(=O)C=C)c3)s2)o1	InChI=1S/C21H22N4O3S2/c1-5-16(26)24-14-8-6-7-13(9-14)19(27)25-20-23-11-18(30-20)29-12-17-22-10-15(28-17)21(2,3)4/h5-11H,1,12H2,2-4H3,(H,24,26)(H,23,25,27)	HMAJGFYNRRZUJX-UHFFFAOYSA-N	50539901	CHEMBL4643057	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1140							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539901	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539901&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137358277	442141464							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333879	CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)o1	InChI=1S/C27H31N5O4S2/c1-5-21(33)30-19-10-8-17(9-11-19)25(35)32-12-6-7-18(15-32)24(34)31-26-29-14-23(38-26)37-16-22-28-13-20(36-22)27(2,3)4/h5,8-11,13-14,18H,1,6-7,12,15-16H2,2-4H3,(H,30,33)(H,29,31,34)	HTFBNTYFTGIOEK-UHFFFAOYSA-N	50539902	CHEMBL4644893	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 99							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539902	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539902&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137358146	442141465							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333880	CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCN(CC3)C(=O)C=C)s2)o1	InChI=1S/C20H26N4O3S2/c1-5-16(25)24-8-6-13(7-9-24)18(26)23-19-22-11-17(29-19)28-12-15-21-10-14(27-15)20(2,3)4/h5,10-11,13H,1,6-9,12H2,2-4H3,(H,22,23,26)	WAFHXBBZJZYUIJ-UHFFFAOYSA-N	50539903	CHEMBL4641226	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 457							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539903&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118418553	442141466							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333881	CC(C)(C)c1cnc(CSc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)o1	InChI=1S/C26H31N5O3S2/c1-5-21(32)29-18-10-8-17(9-11-18)24(33)31-12-6-7-19(15-31)30-25-28-14-23(36-25)35-16-22-27-13-20(34-22)26(2,3)4/h5,8-11,13-14,19H,1,6-7,12,15-16H2,2-4H3,(H,28,30)(H,29,32)/t19-/m1/s1	COGUZYALRYMQTD-LJQANCHMSA-N	50539904	CHEMBL4647764	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6020							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539904&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145749888	442141467							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333882	CC(C)(C)c1cnc(CSc2cnc(N[C@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)o1	InChI=1S/C26H31N5O3S2/c1-5-21(32)29-18-10-8-17(9-11-18)24(33)31-12-6-7-19(15-31)30-25-28-14-23(36-25)35-16-22-27-13-20(34-22)26(2,3)4/h5,8-11,13-14,19H,1,6-7,12,15-16H2,2-4H3,(H,28,30)(H,29,32)/t19-/m0/s1	COGUZYALRYMQTD-IBGZPJMESA-N	50539905	CHEMBL4636090	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539905&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145749923	442141468							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333883	CC(C)(C)c1cnc(CSc2cnc(NC3CCCC(C3)Nc3ccc(NC(=O)C=C)cc3)s2)o1	InChI=1S/C26H33N5O2S2/c1-5-22(32)30-18-11-9-17(10-12-18)29-19-7-6-8-20(13-19)31-25-28-15-24(35-25)34-16-23-27-14-21(33-23)26(2,3)4/h5,9-12,14-15,19-20,29H,1,6-8,13,16H2,2-4H3,(H,28,31)(H,30,32)	KHUWOOWXQFGVBZ-UHFFFAOYSA-N	50539906	CHEMBL4648005::US11142507, Compound MFH-3-35-1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 557							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539906	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539906&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137358323	442141469							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333884	C[C@@H]1[C@@H](CCCN1C(=O)c1ccc(NC(=O)C=C)cc1)Nc1ncc(SCc2ncc(o2)C(C)(C)C)s1	InChI=1S/C27H33N5O3S2/c1-6-22(33)30-19-11-9-18(10-12-19)25(34)32-13-7-8-20(17(32)2)31-26-29-15-24(37-26)36-16-23-28-14-21(35-23)27(3,4)5/h6,9-12,14-15,17,20H,1,7-8,13,16H2,2-5H3,(H,29,31)(H,30,33)/t17-,20-/m1/s1	UYZMRCLCECMQPF-YLJYHZDGSA-N	50539907	CHEMBL4644087	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 7790							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539907	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539907&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			146646288	442141470							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333885	CC(C)(C)c1cnc(CSc2cnc(NC3CN(CC(F)(F)C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)o1	InChI=1S/C26H29F2N5O3S2/c1-5-20(34)31-17-8-6-16(7-9-17)23(35)33-13-18(10-26(27,28)15-33)32-24-30-12-22(38-24)37-14-21-29-11-19(36-21)25(2,3)4/h5-9,11-12,18H,1,10,13-15H2,2-4H3,(H,30,32)(H,31,34)	GAQVCXTZOSXWPY-UHFFFAOYSA-N	50539908	CHEMBL4636175	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9600							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539908	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539908&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145749962	442141471							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333886	C[C@H]1CC[C@H](CN1C(=O)c1ccc(NC(=O)C=C)cc1)Nc1ncc(SCc2ncc(o2)C(C)(C)C)s1	InChI=1S/C27H33N5O3S2/c1-6-22(33)30-19-11-8-18(9-12-19)25(34)32-15-20(10-7-17(32)2)31-26-29-14-24(37-26)36-16-23-28-13-21(35-23)27(3,4)5/h6,8-9,11-14,17,20H,1,7,10,15-16H2,2-5H3,(H,29,31)(H,30,33)/t17-,20+/m0/s1	FPBKUBUKBWJEMH-FXAWDEMLSA-N	50539909	CHEMBL4644643	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 609							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539909	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539909&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145749937	442141472							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333887	CC(C)(C)c1cnc(CSc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cn3)s2)o1	InChI=1S/C25H30N6O3S2/c1-5-20(32)29-16-8-9-18(26-11-16)23(33)31-10-6-7-17(14-31)30-24-28-13-22(36-24)35-15-21-27-12-19(34-21)25(2,3)4/h5,8-9,11-13,17H,1,6-7,10,14-15H2,2-4H3,(H,28,30)(H,29,32)/t17-/m1/s1	UVGATDDZBKJSAL-QGZVFWFLSA-N	50539910	CHEMBL4645334	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3890							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539910&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137358275	442141473							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333888	CC(C)(C)c1cnc(CSc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)c(F)c3)s2)o1	InChI=1S/C26H30FN5O3S2/c1-5-21(33)31-19-9-8-16(11-18(19)27)24(34)32-10-6-7-17(14-32)30-25-29-13-23(37-25)36-15-22-28-12-20(35-22)26(2,3)4/h5,8-9,11-13,17H,1,6-7,10,14-15H2,2-4H3,(H,29,30)(H,31,33)/t17-/m1/s1	APFZUNBSYNZMFG-QGZVFWFLSA-N	50539911	CHEMBL4644198	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5540							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539911	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539911&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			146646573	442141474							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333889	CC(C)(C)c1cnc(CSc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)c(c3)C(F)(F)F)s2)o1	InChI=1S/C27H30F3N5O3S2/c1-5-21(36)34-19-9-8-16(11-18(19)27(28,29)30)24(37)35-10-6-7-17(14-35)33-25-32-13-23(40-25)39-15-22-31-12-20(38-22)26(2,3)4/h5,8-9,11-13,17H,1,6-7,10,14-15H2,2-4H3,(H,32,33)(H,34,36)/t17-/m1/s1	SCNMJGFMXAIFOK-QGZVFWFLSA-N	50539912	CHEMBL4633672	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3490							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539912	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539912&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156011018	442141475							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333890	C=CC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc(SCc2ccncc2)s1	InChI=1S/C24H25N5O2S2/c1-2-21(30)27-19-7-5-18(6-8-19)23(31)29-13-3-4-20(15-29)28-24-26-14-22(33-24)32-16-17-9-11-25-12-10-17/h2,5-12,14,20H,1,3-4,13,15-16H2,(H,26,28)(H,27,30)/t20-/m1/s1	CYUGBWPMMZVPDP-HXUWFJFHSA-N	50539913	CHEMBL4636908	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539913	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539913&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137358290	442141476							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333891	FC(F)(F)c1ncc(CSc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)cn1	InChI=1S/C24H23F3N6O2S2/c1-2-19(34)31-17-7-5-16(6-8-17)21(35)33-9-3-4-18(13-33)32-23-30-12-20(37-23)36-14-15-10-28-22(29-11-15)24(25,26)27/h2,5-8,10-12,18H,1,3-4,9,13-14H2,(H,30,32)(H,31,34)/t18-/m1/s1	QNQVGWPXBWZBQX-GOSISDBHSA-N	50539914	CHEMBL4637498::US11142507, Compound MFH-3-201-1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539914	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539914&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137358263	442141477							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333892	C=CC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc(SCC2CCOCC2)s1	InChI=1S/C24H30N4O3S2/c1-2-21(29)26-19-7-5-18(6-8-19)23(30)28-11-3-4-20(15-28)27-24-25-14-22(33-24)32-16-17-9-12-31-13-10-17/h2,5-8,14,17,20H,1,3-4,9-13,15-16H2,(H,25,27)(H,26,29)/t20-/m1/s1	XPTUNGFRXJHQJG-HXUWFJFHSA-N	50539915	CHEMBL4643754::US11142507, Compound MFH-4-4-1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539915	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539915&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145749966	442141478							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333893	CC(C)(C)c1cnc(CCc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)o1	InChI=1S/C27H33N5O3S/c1-5-23(33)30-19-10-8-18(9-11-19)25(34)32-14-6-7-20(17-32)31-26-29-15-21(36-26)12-13-24-28-16-22(35-24)27(2,3)4/h5,8-11,15-16,20H,1,6-7,12-14,17H2,2-4H3,(H,29,31)(H,30,33)/t20-/m1/s1	NXZXWOASWYOLBZ-HXUWFJFHSA-N	50539916	CHEMBL4636251::US11142507, Compound MFH-3-116-1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539916	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539916&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			126673128	442141479							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333894	CC(C)(C)c1cnc(COCc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)o1	InChI=1S/C27H33N5O4S/c1-5-23(33)30-19-10-8-18(9-11-19)25(34)32-12-6-7-20(15-32)31-26-29-13-21(37-26)16-35-17-24-28-14-22(36-24)27(2,3)4/h5,8-11,13-14,20H,1,6-7,12,15-17H2,2-4H3,(H,29,31)(H,30,33)/t20-/m1/s1	YPSQOIGPBAPUFM-HXUWFJFHSA-N	50539917	CHEMBL4634832::US11142507, Compound MFH-3-128-1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539917	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539917&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145749947	442141480							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333895	CC(C)(C)c1cnc(CNCc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)o1	InChI=1S/C27H34N6O3S/c1-5-23(34)31-19-10-8-18(9-11-19)25(35)33-12-6-7-20(17-33)32-26-30-14-21(37-26)13-28-16-24-29-15-22(36-24)27(2,3)4/h5,8-11,14-15,20,28H,1,6-7,12-13,16-17H2,2-4H3,(H,30,32)(H,31,34)/t20-/m1/s1	BULBBWSMORELAY-HXUWFJFHSA-N	50539918	CHEMBL4632815::US11142507, Compound MFH-3-137-1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8870							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539918	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539918&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145749889	442141481							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333896	CC(C)(C)c1cnc(C[S+]([O-])c2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)o1	InChI=1S/C26H31N5O4S2/c1-5-21(32)29-18-10-8-17(9-11-18)24(33)31-12-6-7-19(15-31)30-25-28-14-23(36-25)37(34)16-22-27-13-20(35-22)26(2,3)4/h5,8-11,13-14,19H,1,6-7,12,15-16H2,2-4H3,(H,28,30)(H,29,32)/t19-,37?/m1/s1	CCGRMLGTKGCLKM-DEQHTHAUSA-N	50539919	CHEMBL4649546	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539919	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539919&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137358369	442141482							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333897	CC(C)(C)c1cnc(CSc2nc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2Cl)o1	InChI=1S/C27H31ClN6O3S/c1-5-22(35)31-18-10-8-17(9-11-18)25(36)34-12-6-7-19(15-34)32-26-30-13-20(28)24(33-26)38-16-23-29-14-21(37-23)27(2,3)4/h5,8-11,13-14,19H,1,6-7,12,15-16H2,2-4H3,(H,31,35)(H,30,32,33)/t19-/m1/s1	PUZGAVMGSWIMSU-LJQANCHMSA-N	50539920	CHEMBL4645503	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5120							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539920	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539920&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156019445	442141483							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333898	CC(C)(C)c1cnc(CSc2nnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)o1	InChI=1S/C25H30N6O3S2/c1-5-20(32)27-17-10-8-16(9-11-17)22(33)31-12-6-7-18(14-31)28-23-29-30-24(36-23)35-15-21-26-13-19(34-21)25(2,3)4/h5,8-11,13,18H,1,6-7,12,14-15H2,2-4H3,(H,27,32)(H,28,29)/t18-/m1/s1	ZGTBRXCHDKWPQT-GOSISDBHSA-N	50539921	CHEMBL4649802::US11142507, Compound MFH-2-25-1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539921&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			145749881	442141484							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51333899	Cc1nc(N[C@@H]2CCCN(C2)C(=O)c2ccc(NC(=O)C=C)cc2)sc1SCc1ncc(o1)C(C)(C)C	InChI=1S/C27H33N5O3S2/c1-6-22(33)30-19-11-9-18(10-12-19)24(34)32-13-7-8-20(15-32)31-26-29-17(2)25(37-26)36-16-23-28-14-21(35-23)27(3,4)5/h6,9-12,14,20H,1,7-8,13,15-16H2,2-5H3,(H,29,31)(H,30,33)/t20-/m1/s1	LXESGOTXIVUNEN-HXUWFJFHSA-N	50539922	CHEMBL4636655	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.9b01929	10.7270/Q25M698Z	32502343			Liu, Y; Hao, M; Leggett, AL; Gao, Y; Ficarro, SB; Che, J; He, Z; Olson, CM; Marto, JA; Kwiatkowski, NP; Zhang, T; Gray, NS	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539922	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539922&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137358102	442141485							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989374	CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3cccc(NC(=O)c4ccc(NC(=O)C=C)cc4)c3)n[nH]c2C1(C)C)c1ccccc1	InChI=1S/C34H38N8O3/c1-6-29(43)35-24-17-15-23(16-18-24)32(44)37-26-14-10-13-25(19-26)36-31-27-20-42(34(2,3)30(27)39-40-31)33(45)38-28(21-41(4)5)22-11-8-7-9-12-22/h6-19,28H,1,20-21H2,2-5H3,(H,35,43)(H,37,44)(H,38,45)(H2,36,39,40)/t28-/m1/s1	VBYGXNURPHQSPG-MUUNZHRXSA-N	50526803	CHEMBL4434871::US10870651, Compound 101	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526803&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			121444083	440735385							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989375	CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3ccc(NC(=O)c4ccc(NC(=O)C=C)cc4)cc3)n[nH]c2C1(C)C)c1ccccc1	InChI=1S/C34H38N8O3/c1-6-29(43)35-24-14-12-23(13-15-24)32(44)37-26-18-16-25(17-19-26)36-31-27-20-42(34(2,3)30(27)39-40-31)33(45)38-28(21-41(4)5)22-10-8-7-9-11-22/h6-19,28H,1,20-21H2,2-5H3,(H,35,43)(H,37,44)(H,38,45)(H2,36,39,40)/t28-/m1/s1	AVLOXJCCPGBYDS-MUUNZHRXSA-N	50526807	CHEMBL4467048::US10870651, Compound 102	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50526807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50526807&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124134260	440735389							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989376	CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3ccc(NC(=O)c4cccc(NC(=O)C=C)c4)cc3)n[nH]c2C1(C)C)c1ccccc1			476716	US10870651, Compound 103	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476716	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476716&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023218	442076762							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989377	CCC(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2n[nH]c3c2CN(C(=O)N[C@H](CN(C)C)c2ccccc2)C3(C)C)c1			476717	US10870651, Compound 104	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476717	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476717&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023219	442076763							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989378	CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3cccc(NC(=O)c4cccc(NC(=O)C=C)c4)c3)n[nH]c2C1(C)C)c1ccccc1			476718	US10870651, Compound 105	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476718&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023220	442076764							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989379	CN(C)CCNC(=O)N1Cc2c(Nc3cccc(NC(=O)c4ccc(NC(=O)C=C)cc4)c3)n[nH]c2C1(C)C	InChI=1S/C28H34N8O3/c1-6-23(37)30-19-12-10-18(11-13-19)26(38)32-21-9-7-8-20(16-21)31-25-22-17-36(27(39)29-14-15-35(4)5)28(2,3)24(22)33-34-25/h6-13,16H,1,14-15,17H2,2-5H3,(H,29,39)(H,30,37)(H,32,38)(H2,31,33,34)	FYSDPHKGVBRASN-UHFFFAOYSA-N	476714	US10870651, Compound 106	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 300							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476714	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476714&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023217	442076760							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989380	CN1CCN(CC1)C(=O)N1Cc2c(Nc3cccc(NC(=O)c4ccc(NC(=O)C=C)cc4)c3)n[nH]c2C1(C)C	InChI=1S/C29H34N8O3/c1-5-24(38)30-20-11-9-19(10-12-20)27(39)32-22-8-6-7-21(17-22)31-26-23-18-37(29(2,3)25(23)33-34-26)28(40)36-15-13-35(4)14-16-36/h5-12,17H,1,13-16,18H2,2-4H3,(H,30,38)(H,32,39)(H2,31,33,34)	OLQDVCOUWQVVHA-UHFFFAOYSA-N	476719	US10870651, Compound 107	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476719&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023221	442076765							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989381	CC(CN(C)C)NC(=O)N1Cc2c(Nc3cccc(NC(=O)c4ccc(NC(=O)C=C)cc4)c3)n[nH]c2C1(C)C			476720	US10870651, Compound 108	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476720&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023222	442076766							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989382	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2n[nH]c3c2CN(C(=O)N[C@H](CO)c2ccccc2)C3(C)C)c1			476721	US10870651, Compound 109	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476721&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023223	442076767							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989383	CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3cccc(NC(=O)C=C)c3)n[nH]c2C1(C)C)c1ccccc1			476722	US10870651, Compound 110	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476722&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023224	442076768							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989384	CN(C)C[C@@H](NC(=O)N1Cc2c(Nc3ccc(NC(=O)C=C)cc3)n[nH]c2C1(C)C)c1ccccc1			476723	US10870651, Compound 111	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 300							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476723	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476723&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023225	442076769							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989385	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3cccc(NC(=O)c4ccc(NC(=O)C=C)cc4)c3)n[nH]c2C1(C)C)c1ccccc1			476724	US10870651, Compound 112	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476724&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023226	442076770							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989386	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)[C@@H]3CCCN(C3)C(=O)C=C)n[nH]c2C1(C)C)c1ccccc1			476725	US10870651, Compound 113	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476725&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023227	442076771							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989387	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)[C@H]3CCCN(C3)C(=O)C=C)n[nH]c2C1(C)C)c1ccccc1			476726	US10870651, Compound 114	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476726&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023228	442076772							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989388	CN(C)C[C@@H](NC(=O)N1Cc2c(NC3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2C1(C)C)c1ccccc1			476727	US10870651, Compound 115	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476727&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023229	442076773							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989389	CN(C)C[C@@H](NC(=O)N1Cc2c(NC3CCN(CC3)C(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2C1(C)C)c1ccccc1			476728	US10870651, Compound 116	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476728&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023230	442076774							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989390	CN(C)C[C@@H](NC(=O)N1Cc2c(N[C@@H]3CCC[C@@H](C3)NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2C1(C)C)c1ccccc1			476729	US10870651, Compound 117	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476729&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023231	442076775							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989391	CN(C)C[C@@H](NC(=O)N1Cc2c(N[C@@H]3CCC[C@H](C3)NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2C1(C)C)c1ccccc1			476730	US10870651, Compound 118	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476730	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476730&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023232	442076776							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989392	CN(C)C[C@@H](NC(=O)N1Cc2c(NC3CCC(CC3)NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2C1(C)C)c1ccccc1			476731	US10870651, Compound 119	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476731&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023233	442076777							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989393	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3cccc(NC(=O)C=C)c3)n[nH]c2C1(C)C)c1ccccc1			476732	US10870651, Compound 120	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476732&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023234	442076778							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989394	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)C3CCN(CC3)C(=O)C=C)n[nH]c2C1(C)C)c1ccccc1			476733	US10870651, Compound 123	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476733	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476733&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023235	442076779							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989395	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2C1(C)C)c1ccccc1			476734	US10870651, Compound 214	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476734	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476734&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023236	442076780							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989396	CCC(=O)Nc1ccc(cc1)C(=O)Nc1n[nH]c2c1CN(C(=O)N[C@H](CN(C)C)c1ccccc1)C2(C)C			476735	US10870651, Compound 215	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476735	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476735&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023237	442076781							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989397	COc1cc(NC(=O)C=C)ccc1C(=O)Nc1n[nH]c2c1CN(C(=O)N[C@H](CN(C)C)c1ccccc1)C2(C)C			476736	US10870651, Compound 216	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476736	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476736&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023238	442076782							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989398	COc1cc(ccc1NC(=O)C=C)C(=O)Nc1n[nH]c2c1CN(C(=O)N[C@H](CN(C)C)c1ccccc1)C2(C)C			476737	US10870651, Compound 217	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476737&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023239	442076783							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989399	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)[C@H]3CC[C@@H](CC3)NC(=O)C=C)n[nH]c2C1(C)C)c1ccccc1			476738	US10870651, Compound 222	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476738	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476738&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023240	442076784							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989400	CN(C)C[C@@H](NC(=O)N1Cc2c(NC3CCN(CC3)C(=O)C=C)n[nH]c2C1(C)C)c1ccccc1			476739	US10870651, Compound 231	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476739	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476739&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023241	442076785							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989401	CN(C)C[C@@H](NC(=O)N1Cc2c(NC3CCCN(C3)C(=O)C=C)n[nH]c2C1(C)C)c1ccccc1			476740	US10870651, Compound 232	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476740	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476740&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023242	442076786							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989402	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2C11CC1)c1ccccc1			476741	US10870651, Compound 233	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476741	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476741&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023243	442076787							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989403	CC(C)[C@H]1N(Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c12)C(=O)N[C@H](CN(C)C)c1ccccc1			476742	US10870651, Compound 234	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476742	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476742&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023244	442076788							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989404	CC(C)[C@@H]1N(Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c12)C(=O)N[C@H](CN(C)C)c1ccccc1			476743	US10870651, Compound 235	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476743	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476743&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023245	442076789							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989405	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2C11CCCCC1)c1ccccc1			476744	US10870651, Compound 236	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 300							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476744	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476744&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023246	442076790							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989406	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2[C@H]1c1ccccc1)c1ccccc1			476745	US10870651, Compound 237::US10870651, Compound 238	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476745&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023247	442076791							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989407	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2[C@H]1c1ccccc1)c1ccccc1			476745	US10870651, Compound 237::US10870651, Compound 238	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476745&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023247	442076791							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989408	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2[C@@H]1c1ccccc1)c1ccccc1			476747	US10870651, Compound 239::US10870651, Compound 240	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476747	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476747&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023248	442076792							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989409	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n[nH]c2[C@@H]1c1ccccc1)c1ccccc1			476747	US10870651, Compound 239::US10870651, Compound 240	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476747	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476747&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156023248	442076792							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989410	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3cccc(NC(=O)C=C)c3)nn(C)c2C1(C)C)c1ccccc1	InChI=1S/C29H35N7O3/c1-7-24(37)30-21-15-11-14-20(16-21)27(38)32-26-22-17-36(29(2,3)25(22)35(6)33-26)28(39)31-23(18-34(4)5)19-12-9-8-10-13-19/h7-16,23H,1,17-18H2,2-6H3,(H,30,37)(H,31,39)(H,32,33,38)/t23-/m1/s1	YANZGRPGNGIGRE-HSZRJFAPSA-N	476750	US10870651, Compound 241	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476750&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			121443949	442076794							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989411	CN(C)C[C@@H](NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)n(C)nc2C1(C)C)c1ccccc1	InChI=1S/C29H35N7O3/c1-7-24(37)30-21-15-13-20(14-16-21)27(38)32-26-22-17-36(29(2,3)25(22)33-35(26)6)28(39)31-23(18-34(4)5)19-11-9-8-10-12-19/h7-16,23H,1,17-18H2,2-6H3,(H,30,37)(H,31,39)(H,32,38)/t23-/m1/s1	ZNSLFIXWQIPEDT-HSZRJFAPSA-N	476752	US10870651, Compound 242	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476752	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476752&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			121444005	442076796							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989412	COc1cc(NC(=O)C=C)ccc1C(=O)Nc1nn(C)c2c1CN(C(=O)N[C@H](CN(C)C)c1ccccc1)C2(C)C	InChI=1S/C30H37N7O4/c1-8-25(38)31-20-14-15-21(24(16-20)41-7)28(39)33-27-22-17-37(30(2,3)26(22)36(6)34-27)29(40)32-23(18-35(4)5)19-12-10-9-11-13-19/h8-16,23H,1,17-18H2,2-7H3,(H,31,38)(H,32,40)(H,33,34,39)/t23-/m1/s1	XCFYHAGBAZTPGS-HSZRJFAPSA-N	476753	US10870651, Compound 243	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476753	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476753&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			121444006	442076797							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989413	COc1cc(NC(=O)C=C)ccc1C(=O)Nc1c2CN(C(=O)N[C@H](CN(C)C)c3ccccc3)C(C)(C)c2nn1C	InChI=1S/C30H37N7O4/c1-8-25(38)31-20-14-15-21(24(16-20)41-7)28(39)33-27-22-17-37(30(2,3)26(22)34-36(27)6)29(40)32-23(18-35(4)5)19-12-10-9-11-13-19/h8-16,23H,1,17-18H2,2-7H3,(H,31,38)(H,32,40)(H,33,39)/t23-/m1/s1	SRLFHMFKYFEFPP-HSZRJFAPSA-N	476754	US10870651, Compound 244	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476754&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			121444008	442076798							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989414	CC(CN(C)C)NC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)nn(C)c2C1(C)C	InChI=1S/C24H33N7O3/c1-8-19(32)26-17-11-9-16(10-12-17)22(33)27-21-18-14-31(23(34)25-15(2)13-29(5)6)24(3,4)20(18)30(7)28-21/h8-12,15H,1,13-14H2,2-7H3,(H,25,34)(H,26,32)(H,27,28,33)	WNOMOCPKNZTWEZ-UHFFFAOYSA-N	476755	US10870651, Compound 245	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476755	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476755&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			137497918	442076799							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
989415	CN(C)C[C@@H](OC(=O)N1Cc2c(NC(=O)c3ccc(NC(=O)C=C)cc3)nn(C)c2C1(C)C)c1ccccc1	InChI=1S/C29H34N6O4/c1-7-24(36)30-21-15-13-20(14-16-21)27(37)31-26-22-17-35(29(2,3)25(22)34(6)32-26)28(38)39-23(18-33(4)5)19-11-9-8-10-12-19/h7-16,23H,1,17-18H2,2-6H3,(H,30,36)(H,31,32,37)/t23-/m1/s1	GMWAVNKSTCWVMZ-HSZRJFAPSA-N	476756	US10870651, Compound 246	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 300							US Patent		10.7270/Q2QZ2F2T		aid1805136	US10870651	Gray, NS; Liang, Y; Zhang, T; Kwiatkowski, NP	Dana-Farber Cancer Institute, Inc.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=476756	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=476756&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			121444010	442076800							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51382906	CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	HKSZLNNOFSGOKW-FYTWVXJKSA-N	2579	(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::CHEMBL388978::Staurosporin, 4::Staurosporine::Staurosporine, 8::US9206188, Staurosporine::US9226923, Staurosporine	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 183							ChEMBL	10.1016/j.bmc.2018.02.022	10.7270/Q2DJ5KB8	29523467			Hou, W; Ren, Y; Zhang, Z; Sun, H; Ma, Y; Yan, B	Beijing Normal University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=2579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=2579&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	STO	1AQ1,1BYG,1E8Z,1NVR,1NXK,1OKY,1Q3D,1QPD,1QPJ,1SM2,1SNU,1STC,1U59,1WVY,1XBC,1XJD,1YHS,2BUJ,2CLQ,2DQ7,2GCD,2HW7,2ITQ,2ITU,2ITW,2NRY,2OIC	44259	8032349	15738	CHEMBL388978		346	C02079	ZINC03814434	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51394348	NC(=O)c1ccc(cn1)-c1ccc(F)c(C(=O)Nc2c[nH]nc2C(=O)Nc2ccc(F)cc2)c1F	InChI=1S/C23H15F3N6O3/c24-12-2-4-13(5-3-12)30-23(35)20-17(10-29-32-20)31-22(34)18-15(25)7-6-14(19(18)26)11-1-8-16(21(27)33)28-9-11/h1-10H,(H2,27,33)(H,29,32)(H,30,35)(H,31,34)	JNYWLVWHCGXRPJ-UHFFFAOYSA-N	50563486	CHEMBL4757951	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>18000							ChEMBL	10.1016/j.ejmech.2021.113281	10.7270/Q2TX3K3W	33611192			Lin, T; Li, J; Liu, L; Li, Y; Jiang, H; Chen, K; Xu, P; Luo, C; Zhou, B	ShanghaiTech University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50563486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50563486&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			162657070	461683824							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51394356	Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1	InChI=1S/C16H17Cl2N5O2/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9/h1-3,8-9,19H,4-7H2,(H,20,23)(H,21,25)(H,22,24)	OVPNQJVDAFNBDN-UHFFFAOYSA-N	50113281	AT-7519	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2400							ChEMBL	10.1016/j.ejmech.2021.113281	10.7270/Q2TX3K3W	33611192			Lin, T; Li, J; Liu, L; Li, Y; Jiang, H; Chen, K; Xu, P; Luo, C; Zhou, B	ShanghaiTech University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113281&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	LZE	7AGA,2VU3	11338033	104007630			DB08142			ZINC13473650	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51389574	Nc1nc(N[C@H]2C[C@@H]3CC[C@H]2C3)sc1C(=O)c1ccccc1[N+]([O-])=O	InChI=1S/C17H18N4O3S/c18-16-15(14(22)11-3-1-2-4-13(11)21(23)24)25-17(20-16)19-12-8-9-5-6-10(12)7-9/h1-4,9-10,12H,5-8,18H2,(H,19,20)/t9-,10+,12+/m1/s1	JRNXAQINDCOHGS-SCVCMEIPSA-N	50561527	CHEMBL4764481	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 555							ChEMBL	10.1021/acsmedchemlett.0c00006	10.7270/Q28W3J0T	33062159			Childers, WE; Elokely, KM; Abou-Gharbia, M	Temple University School of Pharmacy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50561527	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50561527&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	TO7	6W9E	137333456	461831919							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51369037	COc1cc(F)ccc1-c1ncnc(Nc2cccc(CS(C)(=N)=O)c2)n1	InChI=1S/C18H18FN5O2S/c1-26-16-9-13(19)6-7-15(16)17-21-11-22-18(24-17)23-14-5-3-4-12(8-14)10-27(2,20)25/h3-9,11,20H,10H2,1-2H3,(H,21,22,23,24)	ACWKGTGIJRCOOM-UHFFFAOYSA-N	168383	US9669034, 2 (rac)-4-(4-Fluoro-2-methoxyphenyl)-N-{3-[(S-methylsulfonimidoyl)methyl]phenyl}-1,3,5-triazin-2-amine	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>890							ChEMBL	10.1021/acs.jmedchem.0c00744	10.7270/Q2FB56K3	32866383			Wu, T; Qin, Z; Tian, Y; Wang, J; Xu, C; Li, Z; Bian, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=168383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=168383&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			71618220	373987116							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51369038	CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1	InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)	OUSFTKFNBAZUKL-UHFFFAOYSA-N	5931	BMS-387072::CHEMBL296468::N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide::N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide::cid_3025986	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62							ChEMBL	10.1021/acs.jmedchem.0c00744	10.7270/Q2FB56K3	32866383			Wu, T; Qin, Z; Tian, Y; Wang, J; Xu, C; Li, Z; Bian, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5931&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	56H	5D1J	3025986	8035540		CHEMBL296468		5670		ZINC03816409	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51369045	COC[C@H](C)N[C@H]1CC[C@@H](CC1)Nc1cc(c(Cl)cn1)-c1cccc(NCC2(CCOCC2)C#N)n1	InChI=1S/C27H37ClN6O2/c1-19(16-35-2)32-20-6-8-21(9-7-20)33-26-14-22(23(28)15-30-26)24-4-3-5-25(34-24)31-18-27(17-29)10-12-36-13-11-27/h3-5,14-15,19-21,32H,6-13,16,18H2,1-2H3,(H,30,33)(H,31,34)/t19-,20-,21-/m0/s1	XWQVQSXLXAXOPJ-ACRUOGEOSA-N	50553495	CHEMBL4786559	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.0c00744	10.7270/Q2FB56K3	32866383			Wu, T; Qin, Z; Tian, Y; Wang, J; Xu, C; Li, Z; Bian, J	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50553495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50553495&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			68276369	461692263							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51359539	CS(=O)(=O)c1cccc(CNc2nc(Nc3ccc4NC(=O)CCc4c3)ncc2C(F)(F)F)c1	InChI=1S/C22H20F3N5O3S/c1-34(32,33)16-4-2-3-13(9-16)11-26-20-17(22(23,24)25)12-27-21(30-20)28-15-6-7-18-14(10-15)5-8-19(31)29-18/h2-4,6-7,9-10,12H,5,8,11H2,1H3,(H,29,31)(H2,26,27,28,30)	HESLKTSGTIBHJU-UHFFFAOYSA-N	50269948	6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one::CHEMBL514554::D3RKN_2::PF-228::US10266549, Example 32::US10774092, Example 32	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<1000							ChEMBL	10.1021/acsmedchemlett.0c00338	10.7270/Q2DJ5K8C	33488961			Groendyke, BJ; Nabet, B; Mohardt, ML; Zhang, H; Peng, K; Koide, E; Coffey, CR; Che, J; Scott, DA; Bass, AJ; Gray, NS	Dana-Farber Cancer Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50269948	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50269948&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	P4N	6YOJ	11612883	104115362		CHEMBL514554				ZINC35636073	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51358880	CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CC(C)(C)Cc23)c(Cl)cn1	InChI=1S/C22H28ClN5O2/c1-13(29)26-15-6-4-5-14(7-15)21(30)27-20-8-16(18(23)11-24-20)17-10-25-28-12-22(2,3)9-19(17)28/h8,10-11,14-15H,4-7,9,12H2,1-3H3,(H,26,29)(H,24,27,30)/t14-,15+/m0/s1	AVIWDYSJSPOOAR-LSDHHAIUSA-N	50528817	CHEMBL4462530::US10717746, Example 14	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1370							ChEMBL	10.1021/acs.jmedchem.0c01754	10.7270/Q2M90D8V	33306391			Barlaam, B; Casella, R; Cidado, J; Cook, C; De Savi, C; Dishington, A; Donald, CS; Drew, L; Ferguson, AD; Ferguson, D; Glossop, S; Grebe, T; Gu, C; Hande, S; Hawkins, J; Hird, AW; Holmes, J; Horstick, J; Jiang, Y; Lamb, ML; McGuire, TM; Moore, JE; O'Connell, N; Pike, A; Pike, KG; Proia, T; Roberts, B; San Martin, M; Sarkar, U; Shao, W; Stead, D; Sumner, N; Thakur, K; Vasbinder, MM; Varnes, JG; Wang, J; Wang, L; Wu, D; Wu, L; Yang, B; Yao, T	AstraZeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528817&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	Q6E	6Z45	124155204	440737399							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51358881	CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CC(C)(C)Cc23)c(F)cn1	InChI=1S/C22H28FN5O2/c1-13(29)26-15-6-4-5-14(7-15)21(30)27-20-8-16(18(23)11-24-20)17-10-25-28-12-22(2,3)9-19(17)28/h8,10-11,14-15H,4-7,9,12H2,1-3H3,(H,26,29)(H,24,27,30)/t14-,15+/m0/s1	JTIFUJUJDWUQEV-LSDHHAIUSA-N	454542	US10717746, Example 25::US10717746, Example 84	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 548							ChEMBL	10.1021/acs.jmedchem.0c01754	10.7270/Q2M90D8V	33306391			Barlaam, B; Casella, R; Cidado, J; Cook, C; De Savi, C; Dishington, A; Donald, CS; Drew, L; Ferguson, AD; Ferguson, D; Glossop, S; Grebe, T; Gu, C; Hande, S; Hawkins, J; Hird, AW; Holmes, J; Horstick, J; Jiang, Y; Lamb, ML; McGuire, TM; Moore, JE; O'Connell, N; Pike, A; Pike, KG; Proia, T; Roberts, B; San Martin, M; Sarkar, U; Shao, W; Stead, D; Sumner, N; Thakur, K; Vasbinder, MM; Varnes, JG; Wang, J; Wang, L; Wu, D; Wu, L; Yang, B; Yao, T	AstraZeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454542&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124155169	440970408							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51358882	CC(=O)N[C@@H]1CCC[C@@H](C1)C(=O)Nc1cc(-c2cnn3CCCCc23)c(Cl)cn1	InChI=1S/C21H26ClN5O2/c1-13(28)25-15-6-4-5-14(9-15)21(29)26-20-10-16(18(22)12-23-20)17-11-24-27-8-3-2-7-19(17)27/h10-12,14-15H,2-9H2,1H3,(H,25,28)(H,23,26,29)/t14-,15+/m0/s1	AKIBGBJFUGFCIJ-LSDHHAIUSA-N	454519	US10717746, Example 2	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5900							ChEMBL	10.1021/acs.jmedchem.0c01754	10.7270/Q2M90D8V	33306391			Barlaam, B; Casella, R; Cidado, J; Cook, C; De Savi, C; Dishington, A; Donald, CS; Drew, L; Ferguson, AD; Ferguson, D; Glossop, S; Grebe, T; Gu, C; Hande, S; Hawkins, J; Hird, AW; Holmes, J; Horstick, J; Jiang, Y; Lamb, ML; McGuire, TM; Moore, JE; O'Connell, N; Pike, A; Pike, KG; Proia, T; Roberts, B; San Martin, M; Sarkar, U; Shao, W; Stead, D; Sumner, N; Thakur, K; Vasbinder, MM; Varnes, JG; Wang, J; Wang, L; Wu, D; Wu, L; Yang, B; Yao, T	AstraZeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=454519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=454519&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124155310	440970385							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109902	CC(C(=O)Nc1cc([nH]n1)C(C)(C)C)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cc1			525331	US11174232, Compound 9	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525331	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525331&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118342	463788997							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109903	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCOCC2)nc1			525332	US11174232, Compound 10	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525332	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525332&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111106	463788998							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109904	C[C@@H](C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCOCC2)nc1			525333	US11174232, Compound 11	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525333	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525333&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163199807	463788999							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109905	C[C@H](C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCOCC2)nc1			525334	US11174232, Compound 12::US11174232, Compound 93	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525334	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525334&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118377	463789000							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109906	CCC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cc1			525335	US11174232, Compound 13	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525335&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111240	463789001							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109907	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)c(F)c1			525336	US11174232, Compound 14	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525336&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118343	463789002							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109908	CC(C(=O)Nc1cc([nH]n1)C1CCC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cc1			525337	US11174232, Compound 15	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525337	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525337&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111000	463789003							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109909	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cn1			525338	US11174232, Compound 16	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525338&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111033	463789004							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109910	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cc1F			525339	US11174232, Compound 17	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525339&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134562625	463789005							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109911	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)cc1			525340	US11174232, Compound 18	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525340&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111151	463789006							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109912	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)c(F)c1			525341	US11174232, Compound 19	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525341&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111024	463789007							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109913	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)nc1			525342	US11174232, Compound 20	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525342&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111229	463789008							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109914	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)nc1			525343	US11174232, Compound 21::US11174232, Compound 22	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525343&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111229	463789009							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109915	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)nc1			525343	US11174232, Compound 21::US11174232, Compound 22	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525343&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111229	463789009							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109916	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1ccc(F)c(c1)-c1ccc(NC(=O)C=C)c(F)c1			525345	US11174232, Compound 23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525345&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111065	463789010							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109917	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)cn1			525346	US11174232, Compound 24	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525346&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111163	463789011							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109918	CC(C)C(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)c(F)c1			525347	US11174232, Compound 25	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525347&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134562634	463789012							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109919	CCC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)cn1			525348	US11174232, Compound 26	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525348&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111142	463789013							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109920	CCC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)c(F)c1			525349	US11174232, Compound 27	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525349&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124110998	463789014							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109921	CC(C(=O)Nc1cc([nH]n1)C1CCCC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)c(F)c1			525350	US11174232, Compound 28	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525350&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111017	463789015							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109922	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc2N(CCc2c1)C(=O)\C=C\CN(C)C			525351	US11174232, Compound 29	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525351&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111131	463789016							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109923	CC(C(=O)Nc1n[nH]c(C2CC2)c1C)c1cccc(c1)-c1ccc(NC(=O)C=C)cc1			525352	US11174232, Compound 30	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525352&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134562631	463789017							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109924	CCC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)c(F)c1			525353	US11174232, Compound 31	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525353&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111043	463789018							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109925	CCN(CC)C\C=C\C(=O)Nc1ccc(cc1F)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525354	US11174232, Compound 32	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525354&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111187	463789019							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109926	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCCC2)c(F)c1			525355	US11174232, Compound 33	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525355&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111011	463789020							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109927	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCOCC2)c(F)c1			525356	US11174232, Compound 34	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525356&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111069	463789021							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109928	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCOCC2)cn1			525357	US11174232, Compound 35	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525357&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111117	463789022							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109929	CC(C)C(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cn1			525358	US11174232, Compound 36	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525358	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525358&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111159	463789023							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109930	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC\C=C\C(=O)N(C)C)cn1			525359	US11174232, Compound 37	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525359&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111028	463789024							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109931	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)c(F)n1			525360	US11174232, Compound 38	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525360&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111015	463789025							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109932	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCCCC2)cn1			525361	US11174232, Compound 39	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525361&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111184	463789026							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109933	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCCCC2)nc1			525362	US11174232, Compound 40	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525362&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111152	463789027							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109934	COC\C=C\C(=O)Nc1ccc(cn1)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525363	US11174232, Compound 41	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525363&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111221	463789028							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109935	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)nc1			525364	US11174232, Compound 42	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525364&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111135	463789029							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109936	CC(C)C(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)c(F)c1			525365	US11174232, Compound 43	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525365	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525365&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111057	463789030							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109937	CC(C)C(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCOCC2)nc1			525366	US11174232, Compound 44	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525366&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111090	463789031							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109938	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCC(F)C2)nc1			525367	US11174232, Compound 45	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525367	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525367&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111007	463789032							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109939	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CC[C@H](F)C2)nc1			525368	US11174232, Compound 46	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525368	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525368&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111006	463789033							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109940	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CC[C@H](F)C2)nc1			525369	US11174232, Compound 47::US11174232, Compound 48	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525369&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111006	463789034							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109941	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CC[C@H](F)C2)nc1			525369	US11174232, Compound 47::US11174232, Compound 48	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525369&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111006	463789034							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109942	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CC[C@@H](F)C2)nc1			525372	US11174232, Compound 49	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525372&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111219	463789036							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109943	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CC[C@@H](F)C2)nc1			525373	US11174232, Compound 50::US11174232, Compound 51	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525373&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111219	463789037							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109944	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CC[C@@H](F)C2)nc1			525373	US11174232, Compound 50::US11174232, Compound 51	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525373&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111219	463789037							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109945	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCCC2)nc1			525375	US11174232, Compound 52	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525375&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111004	463789038							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109946	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCCC2)nc1			525376	US11174232, Compound 53::US11174232, Compound 54	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525376&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111004	463789039							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109947	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCCC2)nc1			525376	US11174232, Compound 53::US11174232, Compound 54	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525376&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111004	463789039							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109948	CCN(CC)C\C=C\C(=O)Nc1ccc(cn1)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525378	US11174232, Compound 55	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525378&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111078	463789040							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109949	CC(C)C(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)nc1			525379	US11174232, Compound 56	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525379&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111127	463789041							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109950	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCCC(F)C2)nc1			525380	US11174232, Compound 57	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525380&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111013	463789042							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109951	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCOCC2)c(F)n1			525381	US11174232, Compound 58	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525381&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111214	463789043							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109952	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCOCC2)nc1F			525382	US11174232, Compound 59	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525382&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111246	463789044							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109953	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1cncc(NC(=O)\C=C\CN2CCOCC2)c1			525383	US11174232, Compound 60	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525383&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111021	463789045							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109954	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1cccc(NC(=O)\C=C\CN2CCOCC2)c1			525384	US11174232, Compound 61	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525384&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111035	463789046							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109955	CON(C)C\C=C\C(=O)Nc1ccc(cn1)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525385	US11174232, Compound 62	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525385&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111036	463789047							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109956	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1cnc(NC(=O)\C=C\CN2CCOCC2)c(F)c1			525386	US11174232, Compound 63	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525386&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111019	463789048							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109957	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCC(F)C2)c(F)n1			525387	US11174232, Compound 64	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525387&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111005	463789049							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109958	COc1cc(ccc1NC(=O)C=C)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525388	US11174232, Compound 65	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525388&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111030	463789050							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109959	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)c(C)c1			525389	US11174232, Compound 66	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525389&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111115	463789051							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109960	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1cc(C)c(NC(=O)C=C)c(C)c1			525390	US11174232, Compound 67	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525390&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111062	463789052							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109961	COCCN(C)C\C=C\C(=O)Nc1ccc(cn1)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525391	US11174232, Compound 68	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525391&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111139	463789053							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109962	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\Cn2ccnc2)nc1			525392	US11174232, Compound 69	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525392&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118391	463789054							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109963	COC[C@@H]1CCCN1C\C=C\C(=O)Nc1ccc(cn1)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525393	US11174232, Compound 70	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525393&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118366	463789055							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109964	COC[C@@H]1CCCN1C\C=C\C(=O)Nc1ccc(cn1)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525394	US11174232, Compound 71::US11174232, Compound 72	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525394&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118366	463789056							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109965	COC[C@@H]1CCCN1C\C=C\C(=O)Nc1ccc(cn1)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525394	US11174232, Compound 71::US11174232, Compound 72	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525394&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118366	463789056							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109966	COc1cc(NC(=O)C=C)ccc1-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525396	US11174232, Compound 73	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525396&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134562650	463789057							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109967	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(CNC(=O)C=C)nc1			525397	US11174232, Compound 74	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525397&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134562623	463789058							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109968	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)C=C)cc1C			525398	US11174232, Compound 75	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525398&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134562637	463789059							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109969	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc2N(CCc2c1)C(=O)C=C			525399	US11174232, Compound 76	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525399&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163199809	463789060							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109970	COC[C@@H]1C[C@H](F)CN1C\C=C\C(=O)Nc1ccc(cn1)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525400	US11174232, Compound 77	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525400&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134562629	463789061							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109971	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCC(C2)C#N)nc1			525401	US11174232, Compound 78	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525401&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118365	463789062							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109972	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1cncc(NC(=O)C=C)n1			525402	US11174232, Compound 79	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525402&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118411	463789063							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109973	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CC[C@H](F)C2)c(F)c1			525403	US11174232, Compound 80	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525403&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118413	463789064							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109974	COC(=O)[C@@H]1CCCN1C\C=C\C(=O)Nc1ccc(cn1)-c1cccc(c1)C(C)C(=O)Nc1cc([nH]n1)C1CC1			525404	US11174232, Compound 81	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525404&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118412	463789065							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109975	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCC[C@H]2CC#N)nc1			525405	US11174232, Compound 82	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525405&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134562654	463789066							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109976	CCc1cc(Nc2cccc(NC(=O)c3ccc(NC(=O)C=C)cc3)c2)n[nH]1	InChI=1S/C21H21N5O2/c1-3-15-13-19(26-25-15)22-17-6-5-7-18(12-17)24-21(28)14-8-10-16(11-9-14)23-20(27)4-2/h4-13H,2-3H2,1H3,(H,23,27)(H,24,28)(H2,22,25,26)	NCJFRNDCMJMAFJ-UHFFFAOYSA-N	525406	US11174232, Compound 83	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525406&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111207	463789067							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109977	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)C1=CCN(CC1)C(=O)\C=C\CN(C)C			525407	US11174232, Compound 84	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525407&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118414	463789068							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109978	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)C1CCN(CC1)C(=O)\C=C\CN(C)C			525408	US11174232, Compound 85	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525408&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111014	463789069							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109979	Cc1cc(NC(=O)Cc2cccc(c2)-c2ccc(NC(=O)C=C)cc2)n[nH]1	InChI=1S/C21H20N4O2/c1-3-20(26)22-18-9-7-16(8-10-18)17-6-4-5-15(12-17)13-21(27)23-19-11-14(2)24-25-19/h3-12H,1,13H2,2H3,(H,22,26)(H2,23,24,25,27)	UADWXWRNCKWWNR-UHFFFAOYSA-N	525409	US11174232, Compound 86	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 30000							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525409&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118346	463789070							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109980	CCc1cc(NC(=O)C(C)c2cccc(c2)-c2ccc(NC(=O)C=C)cc2)n[nH]1			525410	US11174232, Compound 87	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525410&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118415	463789071							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109981	CC(C(=O)Nc1cc([nH]n1)C(C)(C)C)c1cccc(c1)-c1ccc(NC(=O)C=C)cc1			525411	US11174232, Compound 88	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525411&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118416	463789072							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109982	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2n[nH]c3ccccc23)c1	InChI=1S/C26H26N6O2/c1-32(2)16-6-11-24(33)27-19-14-12-18(13-15-19)26(34)29-21-8-5-7-20(17-21)28-25-22-9-3-4-10-23(22)30-31-25/h3-15,17H,16H2,1-2H3,(H,27,33)(H,29,34)(H2,28,30,31)/b11-6+	RTFSYHAIVUXTEI-IZZDOVSWSA-N	525412	US11174232, Compound 89	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 30000							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525412&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163199810	463789073							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109983	CC(C(=O)Nc1n[nH]c2ccccc12)c1cccc(c1)-c1ccc(NC(=O)C=C)cc1			525413	US11174232, Compound 90	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525413&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163199811	463789074							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109984	CC(C(=O)Nc1n[nH]c2ccccc12)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cc1			525414	US11174232, Compound 91	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525414&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163199812	463789075							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109985	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1cncc(NC(=O)\C=C\CN2CCCC2)n1			525415	US11174232, Compound 92	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525415&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111190	463789076							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109986	C[C@H](C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCOCC2)nc1			525334	US11174232, Compound 12::US11174232, Compound 93	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<25							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525334	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525334&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118377	463789000							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109987	O=C(Nc1ccc(cn1)-c1cccc(c1)C1(CC1)C(=O)Nc1cc([nH]n1)C1CC1)\C=C\CN1CCCC1	InChI=1S/C29H32N6O2/c36-27(7-4-16-35-14-1-2-15-35)31-25-11-10-22(19-30-25)21-5-3-6-23(17-21)29(12-13-29)28(37)32-26-18-24(33-34-26)20-8-9-20/h3-7,10-11,17-20H,1-2,8-9,12-16H2,(H,30,31,36)(H2,32,33,34,37)/b7-4+	KAPLPYXIOOIIAU-QPJJXVBHSA-N	525417	US11174232, Compound 94	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525417&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134562656	463789077							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109988	CC(C)(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN2CCCC2)nc1	InChI=1S/C29H34N6O2/c1-29(2,28(37)32-26-18-24(33-34-26)20-10-11-20)23-8-5-7-21(17-23)22-12-13-25(30-19-22)31-27(36)9-6-16-35-14-3-4-15-35/h5-9,12-13,17-20H,3-4,10-11,14-16H2,1-2H3,(H,30,31,36)(H2,32,33,34,37)/b9-6+	XOXUBALWXREHEV-RMKNXTFCSA-N	525418	US11174232, Compound 95	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525418&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111174	463789078							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109894	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cc1			525323	US11174232, Compound 1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525323&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111020	463788989							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109895	C[C@@H](C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cc1			525324	US11174232, Compound 2	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525324	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525324&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163199805	463788990							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109896	C[C@H](C(=O)Nc1cc([nH]n1)C1CC1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cc1			525325	US11174232, Compound 3	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62.5							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525325&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163199806	463788991							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109897	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1ccc(F)c(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cc1			525326	US11174232, Compound 4	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525326	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525326&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111215	463788992							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109898	CC(C(=O)Nc1cc([nH]n1)C1CC1)c1cc(ccc1F)-c1ccc(NC(=O)\C=C\CN(C)C)cc1			525327	US11174232, Compound 5	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525327	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525327&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111196	463788993							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109899	CC(C(=O)Nc1cc(C2CC2)n(C)n1)c1cccc(c1)-c1ccc(NC(=O)\C=C\CN(C)C)cc1	InChI=1S/C28H33N5O2/c1-19(28(35)30-26-18-25(21-10-11-21)33(4)31-26)22-7-5-8-23(17-22)20-12-14-24(15-13-20)29-27(34)9-6-16-32(2)3/h5-9,12-15,17-19,21H,10-11,16H2,1-4H3,(H,29,34)(H,30,31,35)/b9-6+	IXTBIXXAAKDVJL-RMKNXTFCSA-N	525328	US11174232, Compound 6	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 30000							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525328&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111104	463788994							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109900	CN(C)C\C=C\C(=O)Nc1ccc(cc1)-c1cccc(CC(=O)Nc2cc([nH]n2)C2CC2)c1	InChI=1S/C26H29N5O2/c1-31(2)14-4-7-25(32)27-22-12-10-19(11-13-22)21-6-3-5-18(15-21)16-26(33)28-24-17-23(29-30-24)20-8-9-20/h3-7,10-13,15,17,20H,8-9,14,16H2,1-2H3,(H,27,32)(H2,28,29,30,33)/b7-4+	RDIXRPLZSJLFTI-QPJJXVBHSA-N	525329	US11174232, Compound 7	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525329	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525329&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124111181	463788995							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113526	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCN(C4)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C29H38N8O3/c1-4-25(38)36-12-6-8-21(18-36)27(39)32-23-9-5-7-20(15-23)16-30-29-35-28(33-22-10-13-40-14-11-22)34-26-24(19(2)3)17-31-37(26)29/h4-5,7,9,15,17,19,21-22H,1,6,8,10-14,16,18H2,2-3H3,(H,32,39)(H2,30,33,34,35)	RCPRNUMVRKHPTG-UHFFFAOYSA-N	526531	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-3-carboxamide::US11186576, Compound 1.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526531&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517713	463790165							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113527	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H34N8O3/c1-4-23(36)34-11-8-22(34)25(37)30-20-7-5-6-18(14-20)15-28-27-33-26(31-19-9-12-38-13-10-19)32-24-21(17(2)3)16-29-35(24)27/h4-7,14,16-17,19,22H,1,8-13,15H2,2-3H3,(H,30,37)(H2,28,31,32,33)	JVAPFLBAEURREJ-UHFFFAOYSA-N	526532	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)azetidine-2-carboxamide::US11186576, Compound 2.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526532	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526532&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536931	463790166							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113528	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O3/c1-4-24(37)35-12-6-9-23(35)26(38)31-21-8-5-7-19(15-21)16-29-28-34-27(32-20-10-13-39-14-11-20)33-25-22(18(2)3)17-30-36(25)28/h4-5,7-8,15,17-18,20,23H,1,6,9-14,16H2,2-3H3,(H,31,38)(H2,29,32,33,34)	CQGSKPPSPMWAPE-UHFFFAOYSA-N	526533	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-2-carboxamide::US11186576, Compound 3.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526533&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281404	463790167							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113529	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O3/c1-4-24(37)35-11-8-20(17-35)26(38)31-22-7-5-6-19(14-22)15-29-28-34-27(32-21-9-12-39-13-10-21)33-25-23(18(2)3)16-30-36(25)28/h4-7,14,16,18,20-21H,1,8-13,15,17H2,2-3H3,(H,31,38)(H2,29,32,33,34)	GPDBJFPOOGCXPZ-UHFFFAOYSA-N	526534	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 4.::US11186576, Compound 5.::US11186576, Compound 6.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526534&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122537010	463790168							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113530	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O3/c1-4-24(37)35-11-8-20(17-35)26(38)31-22-7-5-6-19(14-22)15-29-28-34-27(32-21-9-12-39-13-10-21)33-25-23(18(2)3)16-30-36(25)28/h4-7,14,16,18,20-21H,1,8-13,15,17H2,2-3H3,(H,31,38)(H2,29,32,33,34)	GPDBJFPOOGCXPZ-UHFFFAOYSA-N	526534	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 4.::US11186576, Compound 5.::US11186576, Compound 6.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526534&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122537010	463790168							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113531	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O3/c1-4-24(37)35-11-8-20(17-35)26(38)31-22-7-5-6-19(14-22)15-29-28-34-27(32-21-9-12-39-13-10-21)33-25-23(18(2)3)16-30-36(25)28/h4-7,14,16,18,20-21H,1,8-13,15,17H2,2-3H3,(H,31,38)(H2,29,32,33,34)	GPDBJFPOOGCXPZ-UHFFFAOYSA-N	526534	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 4.::US11186576, Compound 5.::US11186576, Compound 6.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526534&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122537010	463790168							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113532	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C30H40N8O3/c1-4-26(39)33-22-10-8-21(9-11-22)28(40)34-24-7-5-6-20(16-24)17-31-30-37-29(35-23-12-14-41-15-13-23)36-27-25(19(2)3)18-32-38(27)30/h4-7,16,18-19,21-23H,1,8-15,17H2,2-3H3,(H,33,39)(H,34,40)(H2,31,35,36,37)/t21-,22+	AXSJQCHFTUTOCQ-SZPZYZBQSA-N	526537	(1,4-cis)-4-acrylamido-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 7.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526537&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301227	463790169							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113533	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCN(C4)C(=O)C=C)c3)nc(NC3CCN(C)CC3)nc12	InChI=1S/C30H41N9O2/c1-5-26(40)38-13-7-9-22(19-38)28(41)33-24-10-6-8-21(16-24)17-31-30-36-29(34-23-11-14-37(4)15-12-23)35-27-25(20(2)3)18-32-39(27)30/h5-6,8,10,16,18,20,22-23H,1,7,9,11-15,17,19H2,2-4H3,(H,33,41)(H2,31,34,35,36)	HMAVGSMOAUBMJF-UHFFFAOYSA-N	526538	1-acryloyl-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-3-carboxamide::US11186576, Compound 8.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526538&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281395	463790170							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113534	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(N[C@H]3CC[C@H](O)CC3)nc12	InChI=1S/C31H42N8O3/c1-4-27(41)34-22-10-8-21(9-11-22)29(42)35-24-7-5-6-20(16-24)17-32-31-38-30(36-23-12-14-25(40)15-13-23)37-28-26(19(2)3)18-33-39(28)31/h4-7,16,18-19,21-23,25,40H,1,8-15,17H2,2-3H3,(H,34,41)(H,35,42)(H2,32,36,37,38)/t21-,22+,23-,25-	ONEXNQKMGKVENG-TWMYTPEGSA-N	526539	(1,4-cis)-4-acrylamido-N-(3-(((2-(((1r,4r)-4-hydroxycyclohexyl)amino)-8- isopropylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 9.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526539&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301269	463790171							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113535	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(NC3CCCC(O)C3)nc12	InChI=1S/C31H42N8O3/c1-4-27(41)34-22-13-11-21(12-14-22)29(42)35-23-8-5-7-20(15-23)17-32-31-38-30(36-24-9-6-10-25(40)16-24)37-28-26(19(2)3)18-33-39(28)31/h4-5,7-8,15,18-19,21-22,24-25,40H,1,6,9-14,16-17H2,2-3H3,(H,34,41)(H,35,42)(H2,32,36,37,38)/t21-,22+,24?,25?	XVCFTTIVYZTNOY-QHSWPGFUSA-N	526540	Isomer-1: 4-acrylamido-N-(3-(((2-((3-hydroxycyclohexyl)amino)-8-isopropyl pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 10.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526540&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517772	463790172							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113536	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(NC3CCCC(O)C3)nc12	InChI=1S/C31H42N8O3/c1-4-27(41)34-22-13-11-21(12-14-22)29(42)35-23-8-5-7-20(15-23)17-32-31-38-30(36-24-9-6-10-25(40)16-24)37-28-26(19(2)3)18-33-39(28)31/h4-5,7-8,15,18-19,21-22,24-25,40H,1,6,9-14,16-17H2,2-3H3,(H,34,41)(H,35,42)(H2,32,36,37,38)/t21-,22-,24?,25?	XVCFTTIVYZTNOY-BXRLGOFVSA-N	526541	Isomer-2: 4-acrylamido-N-(3-(((2-((3-hydroxycyclohexyl)amino)-8-isopropyl pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 11.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526541&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517772	463790173							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113537	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(N[C@H]3CCC[C@@H](O)C3)nc12	InChI=1S/C29H38N8O3/c1-4-25(39)36-12-11-20(17-36)27(40)32-21-8-5-7-19(13-21)15-30-29-35-28(33-22-9-6-10-23(38)14-22)34-26-24(18(2)3)16-31-37(26)29/h4-5,7-8,13,16,18,20,22-23,38H,1,6,9-12,14-15,17H2,2-3H3,(H,32,40)(H2,30,33,34,35)/t20?,22-,23+/m0/s1	MPRGZJIDIZHMNQ-XGELLPRESA-N	526542	Isomer-1: 1-acryloyl-N-(3-(((2-((3-hydroxycyclohexyl)amino)-8-isopropyl pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3- carboxamide::US11186576, Compound 12.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526542&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163199942	463790174							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113538	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(N[C@H]3CCC[C@H](O)C3)nc12	InChI=1S/C29H38N8O3/c1-4-25(39)36-12-11-20(17-36)27(40)32-21-8-5-7-19(13-21)15-30-29-35-28(33-22-9-6-10-23(38)14-22)34-26-24(18(2)3)16-31-37(26)29/h4-5,7-8,13,16,18,20,22-23,38H,1,6,9-12,14-15,17H2,2-3H3,(H,32,40)(H2,30,33,34,35)/t20?,22-,23-/m0/s1	MPRGZJIDIZHMNQ-FALYVICWSA-N	526543	Isomer-2: 1-acryloyl-N-(3-(((2-((3-hydroxycyclohexyl)amino)-8-isopropyl pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3- carboxamide::US11186576, Compound 13.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526543&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163199943	463790175							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113539	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(N[C@@H]3CCNC[C@H]3F)nc12	InChI=1S/C28H36FN9O2/c1-4-24(39)37-11-9-19(16-37)26(40)33-20-7-5-6-18(12-20)13-31-28-36-27(34-23-8-10-30-15-22(23)29)35-25-21(17(2)3)14-32-38(25)28/h4-7,12,14,17,19,22-23,30H,1,8-11,13,15-16H2,2-3H3,(H,33,40)(H2,31,34,35,36)/t19?,22-,23-/m1/s1	KGHZKXNQBOKOPW-QENMJEOYSA-N	526544	1-acryloyl-N-(3-(((2-(((3S,4S)-3-fluoropiperidin-4-yl)amino)-8-isopropyl pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3- carboxamide::US11186576, Compound 14.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526544&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536937	463790176							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113540	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(NC3CCCC(N)C3)nc12	InChI=1S/C29H39N9O2/c1-4-25(39)37-12-11-20(17-37)27(40)33-22-9-5-7-19(13-22)15-31-29-36-28(34-23-10-6-8-21(30)14-23)35-26-24(18(2)3)16-32-38(26)29/h4-5,7,9,13,16,18,20-21,23H,1,6,8,10-12,14-15,17,30H2,2-3H3,(H,33,40)(H2,31,34,35,36)	ADWXJDLAQHGNIE-UHFFFAOYSA-N	526545	1-acryloyl-N-(3-(((2-((3-aminocyclohexyl)amino)-8-isopropylpyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 15.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526545&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281393	463790177							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113541	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCCN4C(=O)C=C)c3)nc(N[C@H]3CCCOC3)nc12	InChI=1S/C29H38N8O3/c1-4-25(38)36-13-6-5-12-24(36)27(39)32-21-10-7-9-20(15-21)16-30-29-35-28(33-22-11-8-14-40-18-22)34-26-23(19(2)3)17-31-37(26)29/h4,7,9-10,15,17,19,22,24H,1,5-6,8,11-14,16,18H2,2-3H3,(H,32,39)(H2,30,33,34,35)/t22-,24?/m0/s1	JIVCYBOEYULWCW-OWJIYDKWSA-N	526546	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-3-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-2-carboxamide::US11186576, Compound 16.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526546	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526546&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517761	463790178							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113542	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN4C(=O)C=C(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C29H38N8O3/c1-18(2)14-25(38)36-11-8-24(36)27(39)32-22-7-5-6-20(15-22)16-30-29-35-28(33-21-9-12-40-13-10-21)34-26-23(19(3)4)17-31-37(26)29/h5-7,14-15,17,19,21,24H,8-13,16H2,1-4H3,(H,32,39)(H2,30,33,34,35)	HVOCJQXJUFXWCM-UHFFFAOYSA-N	526547	N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl) phenyl)-1-(3-methylbut-2-enoyl)azetidine-2- carboxamide::US11186576, Compound 17.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526547&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517860	463790179							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113543	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CN(C4)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H34N8O3/c1-4-23(36)34-15-19(16-34)25(37)30-21-7-5-6-18(12-21)13-28-27-33-26(31-20-8-10-38-11-9-20)32-24-22(17(2)3)14-29-35(24)27/h4-7,12,14,17,19-20H,1,8-11,13,15-16H2,2-3H3,(H,30,37)(H2,28,31,32,33)	YGMLRMQUXKOOCD-UHFFFAOYSA-N	526548	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)azetidine-3-carboxamide::US11186576, Compound 18.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526548&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517775	463790180							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113544	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@H]4CCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H34N8O3/c1-4-23(36)34-11-8-22(34)25(37)30-20-7-5-6-18(14-20)15-28-27-33-26(31-19-9-12-38-13-10-19)32-24-21(17(2)3)16-29-35(24)27/h4-7,14,16-17,19,22H,1,8-13,15H2,2-3H3,(H,30,37)(H2,28,31,32,33)/t22-/m1/s1	JVAPFLBAEURREJ-JOCHJYFZSA-N	526549	(R)-1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)azetidine-2- carboxamide::US11186576, Compound 19.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526549&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536953	463790181							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113545	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H34N8O3/c1-4-23(36)34-11-8-22(34)25(37)30-20-7-5-6-18(14-20)15-28-27-33-26(31-19-9-12-38-13-10-19)32-24-21(17(2)3)16-29-35(24)27/h4-7,14,16-17,19,22H,1,8-13,15H2,2-3H3,(H,30,37)(H2,28,31,32,33)/t22-/m0/s1	JVAPFLBAEURREJ-QFIPXVFZSA-N	526550	(S)-1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)azetidine-2- carboxamide::US11186576, Compound 20.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526550&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536986	463790182							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113546	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C29H38N8O3/c1-4-25(38)36-13-6-5-10-24(36)27(39)32-22-9-7-8-20(16-22)17-30-29-35-28(33-21-11-14-40-15-12-21)34-26-23(19(2)3)18-31-37(26)29/h4,7-9,16,18-19,21,24H,1,5-6,10-15,17H2,2-3H3,(H,32,39)(H2,30,33,34,35)	ZVKYCZNUBZGERI-UHFFFAOYSA-N	526551	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-2-carboxamide::US11186576, Compound 21.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526551&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517764	463790183							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113547	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCC(C4)NC(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C30H40N8O3/c1-4-26(39)33-24-10-6-8-21(16-24)28(40)34-23-9-5-7-20(15-23)17-31-30-37-29(35-22-11-13-41-14-12-22)36-27-25(19(2)3)18-32-38(27)30/h4-5,7,9,15,18-19,21-22,24H,1,6,8,10-14,16-17H2,2-3H3,(H,33,39)(H,34,40)(H2,31,35,36,37)	JBACKISUYQGZGY-UHFFFAOYSA-N	526552	3-acrylamido-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 22.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526552&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517737	463790184							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113548	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CN(CCO4)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O4/c1-4-24(37)35-10-13-40-23(17-35)26(38)31-21-7-5-6-19(14-21)15-29-28-34-27(32-20-8-11-39-12-9-20)33-25-22(18(2)3)16-30-36(25)28/h4-7,14,16,18,20,23H,1,8-13,15,17H2,2-3H3,(H,31,38)(H2,29,32,33,34)	ZIDAIHUEAWEVHL-UHFFFAOYSA-N	526553	4-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)morpholine-2-carboxamide::US11186576, Compound 23.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526553&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517781	463790185							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113549	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4COCCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O4/c1-4-24(37)35-10-13-40-17-23(35)26(38)31-21-7-5-6-19(14-21)15-29-28-34-27(32-20-8-11-39-12-9-20)33-25-22(18(2)3)16-30-36(25)28/h4-7,14,16,18,20,23H,1,8-13,15,17H2,2-3H3,(H,31,38)(H2,29,32,33,34)	KXKRFCPVCYJEIL-UHFFFAOYSA-N	526554	4-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)morpholine-3-carboxamide::US11186576, Compound 24.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526554&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517817	463790186							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113550	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4COCCN4C(=O)C#C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H34N8O4/c1-4-24(37)35-10-13-40-17-23(35)26(38)31-21-7-5-6-19(14-21)15-29-28-34-27(32-20-8-11-39-12-9-20)33-25-22(18(2)3)16-30-36(25)28/h1,5-7,14,16,18,20,23H,8-13,15,17H2,2-3H3,(H,31,38)(H2,29,32,33,34)	UFBFKBXZFSIQKT-UHFFFAOYSA-N	526555	N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-4-propioloylmorpholine-3- carboxamide::US11186576, Compound 25.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526555&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517832	463790187							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113551	CCc1ccc(NC(=O)C2COCCN2C(=O)C=C)cc1CNc1nc(NC2CCOCC2)nc2c(cnn12)C(C)C	InChI=1S/C30H40N8O4/c1-5-20-7-8-23(33-28(40)25-18-42-14-11-37(25)26(39)6-2)15-21(20)16-31-30-36-29(34-22-9-12-41-13-10-22)35-27-24(19(3)4)17-32-38(27)30/h6-8,15,17,19,22,25H,2,5,9-14,16,18H2,1,3-4H3,(H,33,40)(H2,31,34,35,36)	UWPGYPLYDBZYFN-UHFFFAOYSA-N	526556	4-acryloyl-N-(4-ethyl-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)morpholine-3- carboxamide::US11186576, Compound 26.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526556&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517747	463790188							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113552	CC(C)c1cnn2c(NCc3cc(NC(=O)C4CCN4C(=O)C=C)ccc3C)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O3/c1-5-24(37)35-11-8-23(35)26(38)31-21-7-6-18(4)19(14-21)15-29-28-34-27(32-20-9-12-39-13-10-20)33-25-22(17(2)3)16-30-36(25)28/h5-7,14,16-17,20,23H,1,8-13,15H2,2-4H3,(H,31,38)(H2,29,32,33,34)	RIFYCZACTIBQLA-UHFFFAOYSA-N	526557	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)-4-methylphenyl)azetidine-2-carboxamide::US11186576, Compound 27.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526557&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517800	463790189							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113553	CC(C)c1cnn2c(NCc3ccc(C)c(NC(=O)C4CCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O3/c1-5-24(37)35-11-8-23(35)26(38)32-22-14-19(7-6-18(22)4)15-29-28-34-27(31-20-9-12-39-13-10-20)33-25-21(17(2)3)16-30-36(25)28/h5-7,14,16-17,20,23H,1,8-13,15H2,2-4H3,(H,32,38)(H2,29,31,33,34)	OIHNLGJPJPMTFN-UHFFFAOYSA-N	526558	1-acryloyl-N-(5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)-2-methylphenyl)azetidine-2-carboxamide::US11186576, Compound 28.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526558&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517849	463790190							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113554	CC(C)c1cnn2c(NCc3cc(NC(=O)C4CCN4C(=O)C=C)ccc3F)nc(NC3CCOCC3)nc12	InChI=1S/C27H33FN8O3/c1-4-23(37)35-10-7-22(35)25(38)31-19-5-6-21(28)17(13-19)14-29-27-34-26(32-18-8-11-39-12-9-18)33-24-20(16(2)3)15-30-36(24)27/h4-6,13,15-16,18,22H,1,7-12,14H2,2-3H3,(H,31,38)(H2,29,32,33,34)	MKUCXSXCVTWRCQ-UHFFFAOYSA-N	526559	1-acryloyl-N-(4-fluoro-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)azetidine-2-carboxamide::US11186576, Compound 29.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526559&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517719	463790191							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113555	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN4C(=O)C=C)c3F)nc(NC3CCOCC3)nc12	InChI=1S/C27H33FN8O3/c1-4-22(37)35-11-8-21(35)25(38)32-20-7-5-6-17(23(20)28)14-29-27-34-26(31-18-9-12-39-13-10-18)33-24-19(16(2)3)15-30-36(24)27/h4-7,15-16,18,21H,1,8-14H2,2-3H3,(H,32,38)(H2,29,31,33,34)	AGAAENRQSNCCAC-UHFFFAOYSA-N	526560	1-acryloyl-N-(2-fluoro-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)azetidine-2-carboxamide::US11186576, Compound 30.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526560&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536948	463790192							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113556	CC(C)c1cnn2c(NCc3cc(F)cc(NC(=O)C4CCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H33FN8O3/c1-4-23(37)35-8-5-22(35)25(38)31-20-12-17(11-18(28)13-20)14-29-27-34-26(32-19-6-9-39-10-7-19)33-24-21(16(2)3)15-30-36(24)27/h4,11-13,15-16,19,22H,1,5-10,14H2,2-3H3,(H,31,38)(H2,29,32,33,34)	ZGEMGZQHNPREAG-UHFFFAOYSA-N	526561	1-acryloyl-N-(3-fluoro-5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)azetidine-2-carboxamide::US11186576, Compound 31.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526561&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281382	463790193							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113557	CC(C)c1cnn2c(NCc3cc(NC(=O)C4CCN(C4)C(=O)C=C)ccc3F)nc(NC3CCOCC3)nc12	InChI=1S/C28H35FN8O3/c1-4-24(38)36-10-7-18(16-36)26(39)32-21-5-6-23(29)19(13-21)14-30-28-35-27(33-20-8-11-40-12-9-20)34-25-22(17(2)3)15-31-37(25)28/h4-6,13,15,17-18,20H,1,7-12,14,16H2,2-3H3,(H,32,39)(H2,30,33,34,35)	KJXMHLGQPIRMAN-UHFFFAOYSA-N	526562	1-acryloyl-N-(4-fluoro-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3- carboxamide::US11186576, Compound 32.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526562&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536787	463790194							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113558	CC(C)c1cnn2c(NCc3cc(F)cc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H35FN8O3/c1-4-24(38)36-8-5-19(16-36)26(39)32-22-12-18(11-20(29)13-22)14-30-28-35-27(33-21-6-9-40-10-7-21)34-25-23(17(2)3)15-31-37(25)28/h4,11-13,15,17,19,21H,1,5-10,14,16H2,2-3H3,(H,32,39)(H2,30,33,34,35)	VOXFGWXRUYEQNE-UHFFFAOYSA-N	526563	1-acryloyl-N-(3-fluoro-5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3- carboxamide::US11186576, Compound 33.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526563&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536939	463790195							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113559	CC(C)c1cnn2c(NCc3cc(NC(=O)C4CCCCN4C(=O)C=C)ccc3C)nc(NC3CCOCC3)nc12	InChI=1S/C30H40N8O3/c1-5-26(39)37-13-7-6-8-25(37)28(40)33-23-10-9-20(4)21(16-23)17-31-30-36-29(34-22-11-14-41-15-12-22)35-27-24(19(2)3)18-32-38(27)30/h5,9-10,16,18-19,22,25H,1,6-8,11-15,17H2,2-4H3,(H,33,40)(H2,31,34,35,36)	NLRKWNBKZSJEBF-UHFFFAOYSA-N	526564	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)-4-methylphenyl)piperidine-2-carboxamide::US11186576, Compound 34.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526564&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517787	463790196							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113560	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCCN4C(=O)C=C)c3F)nc(NC3CCOCC3)nc12	InChI=1S/C29H37FN8O3/c1-4-24(39)37-13-6-5-10-23(37)27(40)34-22-9-7-8-19(25(22)30)16-31-29-36-28(33-20-11-14-41-15-12-20)35-26-21(18(2)3)17-32-38(26)29/h4,7-9,17-18,20,23H,1,5-6,10-16H2,2-3H3,(H,34,40)(H2,31,33,35,36)	HDEQAJGPRMRXBF-UHFFFAOYSA-N	526565	1-acryloyl-N-(2-fluoro-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-2- carboxamide::US11186576, Compound 35.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526565&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301273	463790197							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113561	CC(C)c1cnn2c(NCc3cc(F)cc(NC(=O)C4CCCCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C29H37FN8O3/c1-4-25(39)37-10-6-5-7-24(37)27(40)33-22-14-19(13-20(30)15-22)16-31-29-36-28(34-21-8-11-41-12-9-21)35-26-23(18(2)3)17-32-38(26)29/h4,13-15,17-18,21,24H,1,5-12,16H2,2-3H3,(H,33,40)(H2,31,34,35,36)	XOZFGRPMLWDGNR-UHFFFAOYSA-N	526566	1-acryloyl-N-(3-fluoro-5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-2- carboxamide::US11186576, Compound 36.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526566&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301253	463790198							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113562	CC(C)c1cnn2c(NCc3cc(NC(=O)C4CCCCN4C(=O)C=C)ccc3F)nc(NC3CCOCC3)nc12	InChI=1S/C29H37FN8O3/c1-4-25(39)37-12-6-5-7-24(37)27(40)33-21-8-9-23(30)19(15-21)16-31-29-36-28(34-20-10-13-41-14-11-20)35-26-22(18(2)3)17-32-38(26)29/h4,8-9,15,17-18,20,24H,1,5-7,10-14,16H2,2-3H3,(H,33,40)(H2,31,34,35,36)	OKGGBEMQENGDSY-UHFFFAOYSA-N	526567	1-acryloyl-N-(4-fluoro-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-2- carboxamide::US11186576, Compound 37.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526567&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301232	463790199							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113563	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3F)nc(NC3CCOCC3)nc12	InChI=1S/C30H39FN8O3/c1-4-25(40)34-21-10-8-19(9-11-21)28(41)36-24-7-5-6-20(26(24)31)16-32-30-38-29(35-22-12-14-42-15-13-22)37-27-23(18(2)3)17-33-39(27)30/h4-7,17-19,21-22H,1,8-16H2,2-3H3,(H,34,40)(H,36,41)(H2,32,35,37,38)/t19-,21+	UHLXABHWADOGJK-TYKWCNGQSA-N	526568	(1,4-cis)-4-acrylamido-N-(2-fluoro-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 38.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526568&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122537011	463790200							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113564	CC(C)c1cnn2c(NCc3cc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)ccc3F)nc(NC3CCOCC3)nc12	InChI=1S/C30H39FN8O3/c1-4-26(40)34-21-7-5-19(6-8-21)28(41)35-23-9-10-25(31)20(15-23)16-32-30-38-29(36-22-11-13-42-14-12-22)37-27-24(18(2)3)17-33-39(27)30/h4,9-10,15,17-19,21-22H,1,5-8,11-14,16H2,2-3H3,(H,34,40)(H,35,41)(H2,32,36,37,38)/t19-,21+	VZWWEOLFBTUSFX-TYKWCNGQSA-N	526569	(1,4-cis)-4-acrylamido-N-(4-fluoro-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 39.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526569&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301293	463790201							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113565	CC(C)c1cnn2c(NCc3cncc(NC(=O)C4COCCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H35N9O4/c1-4-23(37)35-7-10-40-16-22(35)25(38)31-20-11-18(12-28-14-20)13-29-27-34-26(32-19-5-8-39-9-6-19)33-24-21(17(2)3)15-30-36(24)27/h4,11-12,14-15,17,19,22H,1,5-10,13,16H2,2-3H3,(H,31,38)(H2,29,32,33,34)	TYZQGXYAWLLTSU-UHFFFAOYSA-N	526570	4-acryloyl-N-(5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)pyridin-3-yl)morpholine-3-carboxamide::US11186576, Compound 40.::US11186576, Compound 40A.::US11186576, Compound 40B.::US11186576, Compound 40C.::US11186576, Compound 40D.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526570&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536988	463790202							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113566	CC(C)c1cnn2c(NCc3cccc(c3)C(=O)N[C@H]3CCCN(C3)C(=O)C=C)nc(NC3CCOCC3)nc12	InChI=1S/C29H38N8O3/c1-4-25(38)36-12-6-9-23(18-36)32-27(39)21-8-5-7-20(15-21)16-30-29-35-28(33-22-10-13-40-14-11-22)34-26-24(19(2)3)17-31-37(26)29/h4-5,7-8,15,17,19,22-23H,1,6,9-14,16,18H2,2-3H3,(H,32,39)(H2,30,33,34,35)/t23-/m0/s1	KEGHGZFHMWIENR-QHCPKHFHSA-N	526571	(S)-N-(1-acryloylpiperidin-3-yl)-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)benzamide::US11186576, Compound 41.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526571&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536908	463790203							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113567	CC(C)c1cnn2c(NCc3ccc(F)c(NC(=O)C4CCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H33FN8O3/c1-4-23(37)35-10-7-22(35)25(38)32-21-13-17(5-6-20(21)28)14-29-27-34-26(31-18-8-11-39-12-9-18)33-24-19(16(2)3)15-30-36(24)27/h4-6,13,15-16,18,22H,1,7-12,14H2,2-3H3,(H,32,38)(H2,29,31,33,34)	RSIBRBGQEGWZRV-UHFFFAOYSA-N	526572	1-acryloyl-N-(4-fluoro-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)azetidine-2- carboxamide::US11186576, Compound 42.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526572&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301270	463790204							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113568	CC(C)c1cnn2c(NCc3ccc(F)c(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H35FN8O3/c1-4-24(38)36-10-7-19(16-36)26(39)33-23-13-18(5-6-22(23)29)14-30-28-35-27(32-20-8-11-40-12-9-20)34-25-21(17(2)3)15-31-37(25)28/h4-6,13,15,17,19-20H,1,7-12,14,16H2,2-3H3,(H,33,39)(H2,30,32,34,35)	LDURVJVJRHDJIV-UHFFFAOYSA-N	526573	1-acryloyl-N-(2-fluoro-5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3- carboxamide::US11186576, Compound 43.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526573&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301283	463790205							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113569	CC(C)c1cnn2c(NCc3ccc(F)c(NC(=O)C4CCCCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C29H37FN8O3/c1-4-25(39)37-12-6-5-7-24(37)27(40)34-23-15-19(8-9-22(23)30)16-31-29-36-28(33-20-10-13-41-14-11-20)35-26-21(18(2)3)17-32-38(26)29/h4,8-9,15,17-18,20,24H,1,5-7,10-14,16H2,2-3H3,(H,34,40)(H2,31,33,35,36)	JHUHPSALXXQVAT-UHFFFAOYSA-N	526574	1-acryloyl-N-(2-fluoro-5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-2- carboxamide::US11186576, Compound 44.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526574&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536941	463790206							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113570	CC(C)c1cnn2c(NC(C)c3cccc(NC(=O)C4CCCN(C4)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C30H40N8O3/c1-5-26(39)37-13-7-9-22(18-37)28(40)33-24-10-6-8-21(16-24)20(4)32-30-36-29(34-23-11-14-41-15-12-23)35-27-25(19(2)3)17-31-38(27)30/h5-6,8,10,16-17,19-20,22-23H,1,7,9,11-15,18H2,2-4H3,(H,33,40)(H2,32,34,35,36)	ILXGDLOHOSSAFU-UHFFFAOYSA-N	526575	1-acryloyl-N-(3-(1-((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)ethyl)phenyl)piperidine-3- carboxamide::US11186576, Compound 45.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526575&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517738	463790207							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113571	CC(C)c1cnn2c(NCc3cccc(OC(=O)N4CCN(CC4)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O4/c1-4-24(37)34-10-12-35(13-11-34)28(38)40-22-7-5-6-20(16-22)17-29-27-33-26(31-21-8-14-39-15-9-21)32-25-23(19(2)3)18-30-36(25)27/h4-7,16,18-19,21H,1,8-15,17H2,2-3H3,(H2,29,31,32,33)	HKFDRQQVSLTRAR-UHFFFAOYSA-N	526576	3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl 4-acryloylpiperazine-1-carboxylate::US11186576, Compound 46.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526576&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517760	463790208							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113572	CC(C)c1cnn2c(NCc3cccc(NC(=O)c4cccc(NC(=O)C=C)c4)c3)nc(NC3CCOCC3)nc12	InChI=1S/C30H34N8O3/c1-4-26(39)33-24-10-6-8-21(16-24)28(40)34-23-9-5-7-20(15-23)17-31-30-37-29(35-22-11-13-41-14-12-22)36-27-25(19(2)3)18-32-38(27)30/h4-10,15-16,18-19,22H,1,11-14,17H2,2-3H3,(H,33,39)(H,34,40)(H2,31,35,36,37)	VSYJBVCCOVYHPR-UHFFFAOYSA-N	526577	3-acrylamido-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)benzamide::US11186576, Compound 47.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526577&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517818	463790209							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113573	CC(C)c1cnn2c(NCc3cccc(NC(=O)c4ccccc4NC(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C30H34N8O3/c1-4-26(39)35-25-11-6-5-10-23(25)28(40)33-22-9-7-8-20(16-22)17-31-30-37-29(34-21-12-14-41-15-13-21)36-27-24(19(2)3)18-32-38(27)30/h4-11,16,18-19,21H,1,12-15,17H2,2-3H3,(H,33,40)(H,35,39)(H2,31,34,36,37)	WXYJBUJBMFEFAX-UHFFFAOYSA-N	526578	2-acrylamido-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)benzamide::US11186576, Compound 48.::US11186576, Compound 48A.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526578	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526578&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517746	463790210							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113574	CC(C)c1cnn2c(NCc3cccc(NC\C=C\C(=O)N(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C26H36N8O2/c1-18(2)22-17-29-34-24(22)31-25(30-20-10-13-36-14-11-20)32-26(34)28-16-19-7-5-8-21(15-19)27-12-6-9-23(35)33(3)4/h5-9,15,17-18,20,27H,10-14,16H2,1-4H3,(H2,28,30,31,32)/b9-6+	HKTODYRMUXCFAO-RMKNXTFCSA-N	526579	(E)-4-((3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)amino)-N,N-dimethylbut-2-enamide::US11186576, Compound 49.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526579&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517730	463790211							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113575	CCN(CC)C\C=C\C(=O)Nc1cccc(CNc2nc(NC3CCOCC3)nc3c(cnn23)C(C)C)c1	InChI=1S/C28H40N8O2/c1-5-35(6-2)14-8-11-25(37)31-23-10-7-9-21(17-23)18-29-28-34-27(32-22-12-15-38-16-13-22)33-26-24(20(3)4)19-30-36(26)28/h7-11,17,19-20,22H,5-6,12-16,18H2,1-4H3,(H,31,37)(H2,29,32,33,34)/b11-8+	OKWSIRZFWUMJJC-DHZHZOJOSA-N	526580	(E)-4-(diethylamino)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)but-2-enamide::US11186576, Compound 50.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526580	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526580&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517715	463790212							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113576	CC(C)c1cnn2c(NCc3cccc(NC(=O)\C=C\CN4CCOCC4)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H38N8O3/c1-20(2)24-19-30-36-26(24)33-27(32-22-8-13-38-14-9-22)34-28(36)29-18-21-5-3-6-23(17-21)31-25(37)7-4-10-35-11-15-39-16-12-35/h3-7,17,19-20,22H,8-16,18H2,1-2H3,(H,31,37)(H2,29,32,33,34)/b7-4+	WZFYDJKZVZOZQQ-QPJJXVBHSA-N	526581	(E)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-4-morpholinobut-2-enamide::US11186576, Compound 51.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526581	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526581&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517805	463790213							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113577	CC(C)c1cnn2c(NCc3cccc(NC(=O)\C=C\CN(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C26H36N8O2/c1-18(2)22-17-28-34-24(22)31-25(30-20-10-13-36-14-11-20)32-26(34)27-16-19-7-5-8-21(15-19)29-23(35)9-6-12-33(3)4/h5-9,15,17-18,20H,10-14,16H2,1-4H3,(H,29,35)(H2,27,30,31,32)/b9-6+	WOQRHKUMXBMOER-RMKNXTFCSA-N	526582	(E)-4-(dimethylamino)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)but-2-enamide::US11186576, Compound 53.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526582	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526582&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517733	463790214							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113578	CC(C)c1cnn2c(NCc3cccc(NC(=O)\C=C\CN4CCCC4)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H38N8O2/c1-20(2)24-19-30-36-26(24)33-27(32-22-10-15-38-16-11-22)34-28(36)29-18-21-7-5-8-23(17-21)31-25(37)9-6-14-35-12-3-4-13-35/h5-9,17,19-20,22H,3-4,10-16,18H2,1-2H3,(H,31,37)(H2,29,32,33,34)/b9-6+	TWWNLNFZVDCVGK-RMKNXTFCSA-N	526583	(E)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-4-(pyrrolidin-1-yl)but-2-enamide::US11186576, Compound 54.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526583	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526583&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281345	463790215							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113579	CC(C)c1cnn2c(NCc3cccc(NC(=O)\C=C\CN4CCCCC4)c3)nc(NC3CCOCC3)nc12	InChI=1S/C29H40N8O2/c1-21(2)25-20-31-37-27(25)34-28(33-23-11-16-39-17-12-23)35-29(37)30-19-22-8-6-9-24(18-22)32-26(38)10-7-15-36-13-4-3-5-14-36/h6-10,18,20-21,23H,3-5,11-17,19H2,1-2H3,(H,32,38)(H2,30,33,34,35)/b10-7+	QKKNVJXKZQGYTA-JXMROGBWSA-N	526584	(E)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-4-(piperidin-1-yl)but-2-enamide::US11186576, Compound 55.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526584	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526584&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517768	463790216							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113580	CC(C)c1cnn2c(NCc3cccc(NC(=O)\C=C\CN4CCC(F)C4)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H37FN8O2/c1-19(2)24-17-31-37-26(24)34-27(33-22-9-13-39-14-10-22)35-28(37)30-16-20-5-3-6-23(15-20)32-25(38)7-4-11-36-12-8-21(29)18-36/h3-7,15,17,19,21-22H,8-14,16,18H2,1-2H3,(H,32,38)(H2,30,33,34,35)/b7-4+	LNUBFZYACACGRH-QPJJXVBHSA-N	526585	(E)-4-(3-fluoropyrrolidin-1-yl)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)but-2-enamide::US11186576, Compound 56.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526585	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526585&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517878	463790217							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113581	CC(C)c1cnn2c(NCc3cccc(NC(=O)\C=C\CN4CCC(F)(F)C4)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36F2N8O2/c1-19(2)23-17-32-38-25(23)35-26(34-21-8-13-40-14-9-21)36-27(38)31-16-20-5-3-6-22(15-20)33-24(39)7-4-11-37-12-10-28(29,30)18-37/h3-7,15,17,19,21H,8-14,16,18H2,1-2H3,(H,33,39)(H2,31,34,35,36)/b7-4+	QUZBDSGIBSWWNQ-QPJJXVBHSA-N	526586	(E)-4-(3,3-difluoropyrrolidin-1-yl)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran- 4-yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)but-2- enamide::US11186576, Compound 57.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526586	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526586&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517792	463790218							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113582	CC(C)c1cnn2c(NCc3cccc(NC(=O)\C=C\CN4CCCC(F)C4)c3)nc(NC3CCOCC3)nc12	InChI=1S/C29H39FN8O2/c1-20(2)25-18-32-38-27(25)35-28(34-23-10-14-40-15-11-23)36-29(38)31-17-21-6-3-8-24(16-21)33-26(39)9-5-13-37-12-4-7-22(30)19-37/h3,5-6,8-9,16,18,20,22-23H,4,7,10-15,17,19H2,1-2H3,(H,33,39)(H2,31,34,35,36)/b9-5+	RYXVGPSBEVUZKD-WEVVVXLNSA-N	526587	(E)-4-(3-fluoropiperidin-1-yl)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)but-2-enamide::US11186576, Compound 58.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526587	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526587&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517851	463790219							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113583	CC(C)c1cnn2c(NCc3cc(F)cc(NC(=O)\C=C\CN(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C26H35FN8O2/c1-17(2)22-16-29-35-24(22)32-25(31-20-7-10-37-11-8-20)33-26(35)28-15-18-12-19(27)14-21(13-18)30-23(36)6-5-9-34(3)4/h5-6,12-14,16-17,20H,7-11,15H2,1-4H3,(H,30,36)(H2,28,31,32,33)/b6-5+	CEVVVWYWRZPQBX-AATRIKPKSA-N	526588	(E)-4-(dimethylamino)-N-(3-fluoro-5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)but-2-enamide::US11186576, Compound 59.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526588&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517810	463790220							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113584	CC(C)c1cnn2c(NCc3cccc(NC(=O)\C=C\CN(C)C)c3F)nc(NC3CCOCC3)nc12	InChI=1S/C26H35FN8O2/c1-17(2)20-16-29-35-24(20)32-25(30-19-10-13-37-14-11-19)33-26(35)28-15-18-7-5-8-21(23(18)27)31-22(36)9-6-12-34(3)4/h5-9,16-17,19H,10-15H2,1-4H3,(H,31,36)(H2,28,30,32,33)/b9-6+	JXKYAVYGKPRSAR-RMKNXTFCSA-N	526589	(E)-4-(dimethylamino)-N-(2-fluoro-3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4- yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)but-2-enamide::US11186576, Compound 60.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526589&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517839	463790221							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113585	CC(C)c1cnn2c(NCc3cc(F)cc(NC(=O)\C=C\CN4CCOCC4)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H37FN8O3/c1-19(2)24-18-31-37-26(24)34-27(33-22-5-10-39-11-6-22)35-28(37)30-17-20-14-21(29)16-23(15-20)32-25(38)4-3-7-36-8-12-40-13-9-36/h3-4,14-16,18-19,22H,5-13,17H2,1-2H3,(H,32,38)(H2,30,33,34,35)/b4-3+	XIZHDWWWSXBMMA-ONEGZZNKSA-N	526590	(E)-N-(3-fluoro-5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-4-morpholinobut-2- enamide::US11186576, Compound 61.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526590	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526590&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517705	463790222							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113586	CC(C)c1cnn2c(NCc3ccccc3NC(=O)\C=C\CN(C)C)nc(NC3CCOCC3)nc12	InChI=1S/C26H36N8O2/c1-18(2)21-17-28-34-24(21)31-25(29-20-11-14-36-15-12-20)32-26(34)27-16-19-8-5-6-9-22(19)30-23(35)10-7-13-33(3)4/h5-10,17-18,20H,11-16H2,1-4H3,(H,30,35)(H2,27,29,31,32)/b10-7+	BYPDHXDYVICIRN-JXMROGBWSA-N	526591	(E)-4-(dimethylamino)-N-(2-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)but-2-enamide::US11186576, Compound 62.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526591	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526591&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517721	463790223							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113587	CC(C)c1cnn2c(NCc3ccc(NC(=O)\C=C\CN4CCCC4)cc3)nc(NC3CCOCC3)nc12	InChI=1S/C28H38N8O2/c1-20(2)24-19-30-36-26(24)33-27(32-23-11-16-38-17-12-23)34-28(36)29-18-21-7-9-22(10-8-21)31-25(37)6-5-15-35-13-3-4-14-35/h5-10,19-20,23H,3-4,11-18H2,1-2H3,(H,31,37)(H2,29,32,33,34)/b6-5+	HNPSFFXXEOECSM-AATRIKPKSA-N	526592	(E)-N-(4-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a] [1,3,5]triazin-4-yl)amino)methyl)phenyl)-4-(pyrrolidin-1-yl)but-2-enamide::US11186576, Compound 63.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526592	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526592&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517821	463790224							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113588	CC(C)c1cnn2c(NCc3ccc(F)c(NC(=O)C4CCN(C4)C(=O)\C=C\CN(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C31H42FN9O3/c1-20(2)24-18-34-41-28(24)37-30(35-23-10-14-44-15-11-23)38-31(41)33-17-21-7-8-25(32)26(16-21)36-29(43)22-9-13-40(19-22)27(42)6-5-12-39(3)4/h5-8,16,18,20,22-23H,9-15,17,19H2,1-4H3,(H,36,43)(H2,33,35,37,38)/b6-5+	VPUIZGBZFWLVSH-AATRIKPKSA-N	526593	(E)-1-(4-(dimethylamino)but-2-enoyl)-N-(2-fluoro-5-(((8-isopropyl-2- ((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4- yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 64.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526593	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526593&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281336	463790225							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113589	C\C=C\C(=O)N1CCC1C(=O)Nc1cccc(CNc2nc(NC3CCOCC3)nc3c(cnn23)C(C)C)c1	InChI=1S/C28H36N8O3/c1-4-6-24(37)35-12-9-23(35)26(38)31-21-8-5-7-19(15-21)16-29-28-34-27(32-20-10-13-39-14-11-20)33-25-22(18(2)3)17-30-36(25)28/h4-8,15,17-18,20,23H,9-14,16H2,1-3H3,(H,31,38)(H2,29,32,33,34)/b6-4+	JWIHJXRBJGVIJK-GQCTYLIASA-N	526594	(E)-1-(but-2-enoyl)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)azetidine-2-carboxamide::US11186576, Compound 65.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526594	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526594&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536788	463790226							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113590	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN4C(=O)C#C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H32N8O3/c1-4-23(36)34-11-8-22(34)25(37)30-20-7-5-6-18(14-20)15-28-27-33-26(31-19-9-12-38-13-10-19)32-24-21(17(2)3)16-29-35(24)27/h1,5-7,14,16-17,19,22H,8-13,15H2,2-3H3,(H,30,37)(H2,28,31,32,33)	ROCSVCJJFDTHGZ-UHFFFAOYSA-N	526595	N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a][1,3,5] triazin-4-yl)amino)methyl)phenyl)-1-propioloylazetidine-2-carboxamide::US11186576, Compound 66.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526595	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526595&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517804	463790227							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113591	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN4C(=O)C(C)=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O3/c1-17(2)22-16-30-36-24(22)33-27(32-20-9-12-39-13-10-20)34-28(36)29-15-19-6-5-7-21(14-19)31-25(37)23-8-11-35(23)26(38)18(3)4/h5-7,14,16-17,20,23H,3,8-13,15H2,1-2,4H3,(H,31,37)(H2,29,32,33,34)	NQNCIKDFGVCZFY-UHFFFAOYSA-N	526596	N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a] [1,3,5]triazin-4-yl)amino)methyl)phenyl)-1-methacryloylazetidine-2- carboxamide::US11186576, Compound 67.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526596	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526596&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517812	463790228							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113592	COC\C=C\C(=O)N1CCC(C1)C(=O)Nc1cccc(CNc2nc(NC3CCOCC3)nc3c(cnn23)C(C)C)c1	InChI=1S/C30H40N8O4/c1-20(2)25-18-32-38-27(25)35-29(34-23-10-14-42-15-11-23)36-30(38)31-17-21-6-4-7-24(16-21)33-28(40)22-9-12-37(19-22)26(39)8-5-13-41-3/h4-8,16,18,20,22-23H,9-15,17,19H2,1-3H3,(H,33,40)(H2,31,34,35,36)/b8-5+	SDHIXASQHYFOME-VMPITWQZSA-N	526597	(E)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a] [1,3,5]triazin-4-yl)amino)methyl)phenyl)-1-(4-methoxybut-2-enoyl)pyrrolidine-3- carboxamide::US11186576, Compound 68.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526597	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526597&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517842	463790229							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113593	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)\C=C\CN(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C31H43N9O3/c1-21(2)26-19-33-40-28(26)36-30(35-24-11-15-43-16-12-24)37-31(40)32-18-22-7-5-8-25(17-22)34-29(42)23-10-14-39(20-23)27(41)9-6-13-38(3)4/h5-9,17,19,21,23-24H,10-16,18,20H2,1-4H3,(H,34,42)(H2,32,35,36,37)/b9-6+	JDKUPKQKIILYPG-RMKNXTFCSA-N	526598	(E)-1-(4-(dimethylamino)but-2-enoyl)-N-(3-(((8-isopropyl-2-((tetrahydro-2H- pyran-4-yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl) pyrrolidine-3-carboxamide::US11186576, Compound 69.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526598	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526598&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536956	463790230							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113594	CC(C)c1cnn2c(NCc3cc(NC(=O)C4CCN(C4)C(=O)\C=C\CN(C)C)ccc3F)nc(NC3CCOCC3)nc12	InChI=1S/C31H42FN9O3/c1-20(2)25-18-34-41-28(25)37-30(36-23-10-14-44-15-11-23)38-31(41)33-17-22-16-24(7-8-26(22)32)35-29(43)21-9-13-40(19-21)27(42)6-5-12-39(3)4/h5-8,16,18,20-21,23H,9-15,17,19H2,1-4H3,(H,35,43)(H2,33,36,37,38)/b6-5+	LTVXTVYZXLWIFL-AATRIKPKSA-N	526599	(E)-1-(4-(dimethylamino)but-2-enoyl)-N-(4-fluoro-3-(((8-isopropyl-2- ((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino) methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 70.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526599	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526599&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281378	463790231							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113595	CC(C)c1cnn2c(NCc3cc(F)cc(NC(=O)C4CCN(C4)C(=O)\C=C\CN(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C31H42FN9O3/c1-20(2)26-18-34-41-28(26)37-30(36-24-8-12-44-13-9-24)38-31(41)33-17-21-14-23(32)16-25(15-21)35-29(43)22-7-11-40(19-22)27(42)6-5-10-39(3)4/h5-6,14-16,18,20,22,24H,7-13,17,19H2,1-4H3,(H,35,43)(H2,33,36,37,38)/b6-5+	VODRZEHGMHREHX-AATRIKPKSA-N	526600	(E)-1-(4-(dimethylamino)but-2-enoyl)-N-(3-fluoro-5-(((8-isopropyl-2- ((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino) methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 71.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526600&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536795	463790232							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113596	CC(C)c1cnn2c(NC(C)c3cccc(NC(=O)C4CCCN(C4)C(=O)\C=C\CN(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C33H47N9O3/c1-22(2)28-20-34-42-30(28)38-32(37-26-13-17-45-18-14-26)39-33(42)35-23(3)24-9-6-11-27(19-24)36-31(44)25-10-7-16-41(21-25)29(43)12-8-15-40(4)5/h6,8-9,11-12,19-20,22-23,25-26H,7,10,13-18,21H2,1-5H3,(H,36,44)(H2,35,37,38,39)/b12-8+	ZQYFMUWPCUPRLF-XYOKQWHBSA-N	526601	(E)-1-(4-(dimethylamino)but-2-enoyl)-N-(3-(1-((8-isopropyl-2-((tetrahydro-2H- pyran-4-yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)ethyl)phenyl) piperidine-3-carboxamide::US11186576, Compound 72.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526601&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536799	463790233							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113597	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4COCCN4C(=O)\C=C\CN(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C31H43N9O4/c1-21(2)25-19-33-40-28(25)36-30(35-23-10-14-43-15-11-23)37-31(40)32-18-22-7-5-8-24(17-22)34-29(42)26-20-44-16-13-39(26)27(41)9-6-12-38(3)4/h5-9,17,19,21,23,26H,10-16,18,20H2,1-4H3,(H,34,42)(H2,32,35,36,37)/b9-6+	PFCJWJBGZLLSPN-RMKNXTFCSA-N	526602	(E)-4-(4-(dimethylamino)but-2-enoyl)-N-(3-(((8-isopropyl-2-((tetrahydro-2H- pyran-4-yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl) morpholine-3-carboxamide::US11186576, Compound 73.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526602&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517823	463790234							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113598	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCCN4C(=O)\C=C\CN(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C32H45N9O3/c1-22(2)26-21-34-41-29(26)37-31(36-24-13-17-44-18-14-24)38-32(41)33-20-23-9-7-10-25(19-23)35-30(43)27-11-5-6-16-40(27)28(42)12-8-15-39(3)4/h7-10,12,19,21-22,24,27H,5-6,11,13-18,20H2,1-4H3,(H,35,43)(H2,33,36,37,38)/b12-8+	GPZOORUBIOAJQH-XYOKQWHBSA-N	526603	(E)-1-(4-(dimethylamino)but-2-enoyl)-N-(3-(((8-isopropyl-2-((tetrahydro-2H- pyran-4-yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl) piperidine-2-carboxamide::US11186576, Compound 74.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526603&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536911	463790235							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113599	CC(C)c1cnn2c(NCc3cccc(OC(=O)N4CCN(CC4)C(=O)\C=C\CN(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C31H43N9O4/c1-22(2)26-21-33-40-28(26)35-29(34-24-10-17-43-18-11-24)36-30(40)32-20-23-7-5-8-25(19-23)44-31(42)39-15-13-38(14-16-39)27(41)9-6-12-37(3)4/h5-9,19,21-22,24H,10-18,20H2,1-4H3,(H2,32,34,35,36)/b9-6+	WVQFDCQUNSNFLF-RMKNXTFCSA-N	526604	3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a][1,3,5] triazin-4-yl)amino)methyl)phenyl(E)-4-(4-(dimethylamino)but-2-enoyl) piperazine-1-carboxylate::US11186576, Compound 75.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526604	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526604&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517720	463790236							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113600	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN4C\C=C\C(=O)N(C)C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C30H41N9O3/c1-20(2)24-19-32-39-27(24)35-29(34-22-11-15-42-16-12-22)36-30(39)31-18-21-7-5-8-23(17-21)33-28(41)25-10-14-38(25)13-6-9-26(40)37(3)4/h5-9,17,19-20,22,25H,10-16,18H2,1-4H3,(H,33,41)(H2,31,34,35,36)/b9-6+	YQHICWQULKSENB-RMKNXTFCSA-N	526605	(E)-1-(4-(dimethylamino)-4-oxobut-2-en-1-yl)-N-(3-(((8-isopropyl-2-((tetrahydro- 2H-pyran-4-yl)amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl) phenyl)azetidine-2-carboxamide::US11186576, Compound 76.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526605&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517778	463790237							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113601	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCCN4C(=O)\C=C\CN4CCCC4)c3)nc(NC3CCOCC3)nc12	InChI=1S/C34H47N9O3/c1-24(2)28-23-36-43-31(28)39-33(38-26-13-19-46-20-14-26)40-34(43)35-22-25-9-7-10-27(21-25)37-32(45)29-11-3-4-18-42(29)30(44)12-8-17-41-15-5-6-16-41/h7-10,12,21,23-24,26,29H,3-6,11,13-20,22H2,1-2H3,(H,37,45)(H2,35,38,39,40)/b12-8+	FFQZKGLSLQPVMU-XYOKQWHBSA-N	526606	(E)-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-1-(4-(pyrrolidin-1-yl)but-2- enoyl)piperidine-2-carboxamide::US11186576, Compound 77.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526606	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526606&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517848	463790238							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113602	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCCN4S(=O)(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H38N8O4S/c1-4-41(38,39)35-13-6-5-10-24(35)26(37)31-22-9-7-8-20(16-22)17-29-28-34-27(32-21-11-14-40-15-12-21)33-25-23(19(2)3)18-30-36(25)28/h4,7-9,16,18-19,21,24H,1,5-6,10-15,17H2,2-3H3,(H,31,37)(H2,29,32,33,34)	ZFXCSJQRWGKURW-UHFFFAOYSA-N	526607	N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-1-(vinylsulfonyl)piperidine-2- carboxamide::US11186576, Compound 78.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526607	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526607&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517725	463790239							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113603	CC(C)c1cnn2c(NCc3cccc(NC(=O)CNC(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C25H32N8O3/c1-4-21(34)26-15-22(35)29-19-7-5-6-17(12-19)13-27-25-32-24(30-18-8-10-36-11-9-18)31-23-20(16(2)3)14-28-33(23)25/h4-7,12,14,16,18H,1,8-11,13,15H2,2-3H3,(H,26,34)(H,29,35)(H2,27,30,31,32)	CXTABNZRGMICIQ-UHFFFAOYSA-N	526608	N-(2-((3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)amino)-2-oxoethyl)acrylamide::US11186576, Compound 79.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526608	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526608&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517750	463790240							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113604	CC(C)c1cnn2c(NCc3cccc(NC(=O)C(C)NC(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C26H34N8O3/c1-5-22(35)29-17(4)24(36)30-20-8-6-7-18(13-20)14-27-26-33-25(31-19-9-11-37-12-10-19)32-23-21(16(2)3)15-28-34(23)26/h5-8,13,15-17,19H,1,9-12,14H2,2-4H3,(H,29,35)(H,30,36)(H2,27,31,32,33)	BJLMYRWVVGYHKB-UHFFFAOYSA-N	526609	N-(1-((3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)amino)-1-oxopropan-2-yl)acrylamide::US11186576, Compound 80.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526609	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526609&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517831	463790241							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113605	CC(C)c1cnn2c(NCc3cccc(NC(=O)CN(C)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C26H34N8O3/c1-5-23(36)33(4)16-22(35)29-20-8-6-7-18(13-20)14-27-26-32-25(30-19-9-11-37-12-10-19)31-24-21(17(2)3)15-28-34(24)26/h5-8,13,15,17,19H,1,9-12,14,16H2,2-4H3,(H,29,35)(H2,27,30,31,32)	HGCPZAMFEQEXNN-UHFFFAOYSA-N	526610	N-(2-((3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)amino)-2-oxoethyl)-N-methyl acrylamide::US11186576, Compound 81.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526610&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517795	463790242							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113606	CC(C)c1cnn2c(NCc3cccc(NC(=O)C(C)(C)NC(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H36N8O3/c1-6-22(36)34-27(4,5)24(37)30-20-9-7-8-18(14-20)15-28-26-33-25(31-19-10-12-38-13-11-19)32-23-21(17(2)3)16-29-35(23)26/h6-9,14,16-17,19H,1,10-13,15H2,2-5H3,(H,30,37)(H,34,36)(H2,28,31,32,33)	MYIKYBZQJIHUDS-UHFFFAOYSA-N	526611	N-(1-((3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)amino)-2-methyl-1-oxopropan-2- yl)acrylamide::US11186576, Compound 82.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526611	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526611&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517806	463790243							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113607	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4(CC4)NC(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H34N8O3/c1-4-22(36)34-27(10-11-27)24(37)30-20-7-5-6-18(14-20)15-28-26-33-25(31-19-8-12-38-13-9-19)32-23-21(17(2)3)16-29-35(23)26/h4-7,14,16-17,19H,1,8-13,15H2,2-3H3,(H,30,37)(H,34,36)(H2,28,31,32,33)	HOAOZRUPBGVQAO-UHFFFAOYSA-N	526612	1-acrylamido-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo [1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclopropane-1-carboxamide::US11186576, Compound 83.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526612&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517862	463790244							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113608	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4(CC4)N(C)C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H36N8O3/c1-5-23(37)35(4)28(11-12-28)25(38)31-21-8-6-7-19(15-21)16-29-27-34-26(32-20-9-13-39-14-10-20)33-24-22(18(2)3)17-30-36(24)27/h5-8,15,17-18,20H,1,9-14,16H2,2-4H3,(H,31,38)(H2,29,32,33,34)	MWNGEJKYCFSGQY-UHFFFAOYSA-N	526613	N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a] [1,3,5]triazin-4-yl)amino)methyl)phenyl)-1-(N-methylacrylamido)cyclopropane- 1-carboxamide::US11186576, Compound 84.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526613	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526613&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281347	463790245							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113609	CC(C)c1cnn2c(NCc3cccc(NC(=O)c4nn(C)cc4NC(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C28H34N10O3/c1-5-23(39)33-22-16-37(4)36-24(22)26(40)31-20-8-6-7-18(13-20)14-29-28-35-27(32-19-9-11-41-12-10-19)34-25-21(17(2)3)15-30-38(25)28/h5-8,13,15-17,19H,1,9-12,14H2,2-4H3,(H,31,40)(H,33,39)(H2,29,32,34,35)	VSIOELSCXPKQDT-UHFFFAOYSA-N	526614	4-acrylamido-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo [1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)-1-methyl-1H-pyrazole-3- carboxamide::US11186576, Compound 85.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526614&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517710	463790246							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113610	CC(C)c1cnn2c(Nc3cccc(NC(=O)C4CCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C26H32N8O3/c1-4-22(35)33-11-8-21(33)24(36)28-18-6-5-7-19(14-18)30-26-32-25(29-17-9-12-37-13-10-17)31-23-20(16(2)3)15-27-34(23)26/h4-7,14-17,21H,1,8-13H2,2-3H3,(H,28,36)(H2,29,30,31,32)	OWIILOSCDYFKNT-UHFFFAOYSA-N	526615	1-acryloyl-N-(3-((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)phenyl)azetidine-2-carboxamide::US11186576, Compound 86.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526615&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517802	463790247							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113611	CCc1cnn2c(NCc3cccc(NC(=O)C4CCN(CC4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H38N8O3/c1-4-21-19-31-37-26(21)33-29(40-24-11-13-35(3)14-12-24)34-28(37)30-18-20-7-6-8-23(17-20)32-27(39)22-9-15-36(16-10-22)25(38)5-2/h5-8,17,19,22,24H,2,4,9-16,18H2,1,3H3,(H,32,39)(H,30,33,34)	UAKAWJUFHDSOJH-UHFFFAOYSA-N	526616	1-acryloyl-N-(3-(((8-ethyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5] triazin-4-yl)amino)methyl)phenyl)piperidine-4-carboxamide::US11186576, Compound 88.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526616&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517728	463790248							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113612	CCc1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C30H40N8O3/c1-4-21-19-32-38-27(21)35-30(41-25-13-15-37(3)16-14-25)36-29(38)31-18-20-7-6-8-24(17-20)34-28(40)22-9-11-23(12-10-22)33-26(39)5-2/h5-8,17,19,22-23,25H,2,4,9-16,18H2,1,3H3,(H,33,39)(H,34,40)(H,31,35,36)/t22-,23+	OGQPSBCSTPMCNT-ZRZAMGCNSA-N	526617	(1,4-cis)-4-acrylamido-N-(3-(((8-ethyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo [1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1-carboxamide::US11186576, Compound 90.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526617&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536944	463790249							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113613	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C31H42N8O3/c1-5-27(40)34-23-11-9-22(10-12-23)29(41)35-24-8-6-7-21(17-24)18-32-30-37-31(42-25-13-15-38(4)16-14-25)36-28-26(20(2)3)19-33-39(28)30/h5-8,17,19-20,22-23,25H,1,9-16,18H2,2-4H3,(H,34,40)(H,35,41)(H,32,36,37)/t22-,23-	RQRWQOCGMQHYHY-YHBQERECSA-N	526618	(1,4-trans)-4-acrylamido-N-(3-(((8-isoproprayl-2-((1-methylpiperidin-4-yl)oxy) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 91.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526618&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301315	463790250							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113614	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCN(C)CC3F)nc12	InChI=1S/C31H41FN8O3/c1-5-27(41)35-22-11-9-21(10-12-22)29(42)36-23-8-6-7-20(15-23)16-33-30-38-31(43-26-13-14-39(4)18-25(26)32)37-28-24(19(2)3)17-34-40(28)30/h5-8,15,17,19,21-22,25-26H,1,9-14,16,18H2,2-4H3,(H,35,41)(H,36,42)(H,33,37,38)/t21-,22+,25?,26?	ZOEDZFYWVFXKRK-PJYWLYPCSA-N	526619	Isomer-1: 4-acrylamido-N-(3-(((2-((3-fluoro-1-methylpiperidin-4-yl)amino)-8- isopropylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 92.::US11186576, Compound 93.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526619&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301292	463790251							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113615	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCN(C)CC3F)nc12	InChI=1S/C31H41FN8O3/c1-5-27(41)35-22-11-9-21(10-12-22)29(42)36-23-8-6-7-20(15-23)16-33-30-38-31(43-26-13-14-39(4)18-25(26)32)37-28-24(19(2)3)17-34-40(28)30/h5-8,15,17,19,21-22,25-26H,1,9-14,16,18H2,2-4H3,(H,35,41)(H,36,42)(H,33,37,38)/t21-,22+,25?,26?	ZOEDZFYWVFXKRK-PJYWLYPCSA-N	526619	Isomer-1: 4-acrylamido-N-(3-(((2-((3-fluoro-1-methylpiperidin-4-yl)amino)-8- isopropylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 92.::US11186576, Compound 93.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526619&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301292	463790251							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113616	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN4C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C28H36N8O3/c1-5-24(37)35-14-11-23(35)26(38)31-20-8-6-7-19(15-20)16-29-27-33-28(39-21-9-12-34(4)13-10-21)32-25-22(18(2)3)17-30-36(25)27/h5-8,15,17-18,21,23H,1,9-14,16H2,2-4H3,(H,31,38)(H,29,32,33)	SRTKYXXYKOVFFH-UHFFFAOYSA-N	526621	1-acryloyl-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)azetidine-2-carboxamide::US11186576, Compound 94.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526621&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517846	463790252							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113617	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(OC3CCOCC3)nc12	InChI=1S/C28H35N7O4/c1-4-24(36)34-11-8-20(17-34)26(37)31-21-7-5-6-19(14-21)15-29-27-33-28(39-22-9-12-38-13-10-22)32-25-23(18(2)3)16-30-35(25)27/h4-7,14,16,18,20,22H,1,8-13,15,17H2,2-3H3,(H,31,37)(H,29,32,33)	FLMPKZIXVAZXPI-UHFFFAOYSA-N	526622	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 95.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526622&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281341	463790253							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113618	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCN(C4)C(=O)C=C)c3)nc(OC3CCOCC3)nc12	InChI=1S/C29H37N7O4/c1-4-25(37)35-12-6-8-21(18-35)27(38)32-22-9-5-7-20(15-22)16-30-28-34-29(40-23-10-13-39-14-11-23)33-26-24(19(2)3)17-31-36(26)28/h4-5,7,9,15,17,19,21,23H,1,6,8,10-14,16,18H2,2-3H3,(H,32,38)(H,30,33,34)	BWHOKMJVCFLALP-UHFFFAOYSA-N	526623	1-acryloyl-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-3-carboxamide::US11186576, Compound 96.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526623&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281396	463790254							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113619	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCOCC3)nc12	InChI=1S/C30H39N7O4/c1-4-26(38)33-22-10-8-21(9-11-22)28(39)34-23-7-5-6-20(16-23)17-31-29-36-30(41-24-12-14-40-15-13-24)35-27-25(19(2)3)18-32-37(27)29/h4-7,16,18-19,21-22,24H,1,8-15,17H2,2-3H3,(H,33,38)(H,34,39)(H,31,35,36)/t21-,22+	LZCJNFCRDXNQDP-SZPZYZBQSA-N	526624	(1,4-cis)-4-acrylamido-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)oxy) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 97.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526624&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301264	463790255							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113620	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCOCC3F)nc12	InChI=1S/C30H38FN7O4/c1-4-26(39)34-21-10-8-20(9-11-21)28(40)35-22-7-5-6-19(14-22)15-32-29-37-30(42-25-12-13-41-17-24(25)31)36-27-23(18(2)3)16-33-38(27)29/h4-7,14,16,18,20-21,24-25H,1,8-13,15,17H2,2-3H3,(H,34,39)(H,35,40)(H,32,36,37)/t20-,21+,24?,25?	ZEZIQUAVXMWMHQ-JUJAOGAQSA-N	526625	Isomer-1: 4-acrylamido-N-(3-(((2-((3-fluorotetrahydro-2H-pyran-4-yl)oxy)-8- isopropylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 98.::US11186576, Compound 99.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526625	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526625&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517906	463790256							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113621	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCOCC3F)nc12	InChI=1S/C30H38FN7O4/c1-4-26(39)34-21-10-8-20(9-11-21)28(40)35-22-7-5-6-19(14-22)15-32-29-37-30(42-25-12-13-41-17-24(25)31)36-27-23(18(2)3)16-33-38(27)29/h4-7,14,16,18,20-21,24-25H,1,8-13,15,17H2,2-3H3,(H,34,39)(H,35,40)(H,32,36,37)/t20-,21+,24?,25?	ZEZIQUAVXMWMHQ-JUJAOGAQSA-N	526625	Isomer-1: 4-acrylamido-N-(3-(((2-((3-fluorotetrahydro-2H-pyran-4-yl)oxy)-8- isopropylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 98.::US11186576, Compound 99.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526625	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526625&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517906	463790256							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113622	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCOC3)nc12	InChI=1S/C29H37N7O4/c1-4-25(37)32-21-10-8-20(9-11-21)27(38)33-22-7-5-6-19(14-22)15-30-28-35-29(40-23-12-13-39-17-23)34-26-24(18(2)3)16-31-36(26)28/h4-7,14,16,18,20-21,23H,1,8-13,15,17H2,2-3H3,(H,32,37)(H,33,38)(H,30,34,35)/t20-,21+,23?	WGVBJIOWQJASCQ-TYABSZSSSA-N	526627	(1,4-cis)-4-acrylamido-N-(3-(((8-isopropyl-2-((tetrahydrofuran-3-yl)oxy)pyrazolo [1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1-carboxamide::US11186576, Compound 100.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526627&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301318	463790257							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113623	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCN(C)C3)nc12	InChI=1S/C30H40N8O3/c1-5-26(39)33-22-11-9-21(10-12-22)28(40)34-23-8-6-7-20(15-23)16-31-29-36-30(41-24-13-14-37(4)18-24)35-27-25(19(2)3)17-32-38(27)29/h5-8,15,17,19,21-22,24H,1,9-14,16,18H2,2-4H3,(H,33,39)(H,34,40)(H,31,35,36)/t21-,22+,24?	WLXLYPHNHSERKW-RIKCKFAHSA-N	526628	(1,4-cis)-4-acrylamido-N-(3-(((8-isopropyl-2-((1-methylpyrrolidin-3-yl)oxy) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 101.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526628&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301328	463790258							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113624	CC(C)COc1nc(NCc2cccc(NC(=O)C3CCN(C3)C(=O)C=C)c2)n2ncc(C(C)C)c2n1	InChI=1S/C27H35N7O3/c1-6-23(35)33-11-10-20(15-33)25(36)30-21-9-7-8-19(12-21)13-28-26-32-27(37-16-17(2)3)31-24-22(18(4)5)14-29-34(24)26/h6-9,12,14,17-18,20H,1,10-11,13,15-16H2,2-5H3,(H,30,36)(H,28,31,32)	WXPUVOYPDRURKR-UHFFFAOYSA-N	526629	1-acryloyl-N-(3-(((2-isobutoxy-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-4- yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 102.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526629&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517765	463790259							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113625	COCCOc1nc(NCc2cccc(NC(=O)C3CCN(C3)C(=O)C=C)c2)n2ncc(C(C)C)c2n1	InChI=1S/C26H33N7O4/c1-5-22(34)32-10-9-19(16-32)24(35)29-20-8-6-7-18(13-20)14-27-25-31-26(37-12-11-36-4)30-23-21(17(2)3)15-28-33(23)25/h5-8,13,15,17,19H,1,9-12,14,16H2,2-4H3,(H,29,35)(H,27,30,31)	IZLKPZFDMWBZLM-UHFFFAOYSA-N	526630	1-acryloyl-N-(3-(((8-isopropyl-2-(2-methoxyethoxy)pyrazolo[1,5-a][1,3,5]triazin- 4-yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 103.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526630&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517749	463790260							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113626	COCCOCCOc1nc(NCc2cccc(NC(=O)C3CCN(C3)C(=O)C=C)c2)n2ncc(C(C)C)c2n1	InChI=1S/C28H37N7O5/c1-5-24(36)34-10-9-21(18-34)26(37)31-22-8-6-7-20(15-22)16-29-27-33-28(40-14-13-39-12-11-38-4)32-25-23(19(2)3)17-30-35(25)27/h5-8,15,17,19,21H,1,9-14,16,18H2,2-4H3,(H,31,37)(H,29,32,33)	IAPOTAHTLZCKMS-UHFFFAOYSA-N	526631	1-acryloyl-N-(3-(((8-isopropyl-2-(2-(2-methoxyethoxy)ethoxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::US11186576, Compound 104.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526631&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134281359	463790261							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113627	CN1CCC(CC1)Oc1nc(NCc2cccc(NC(=O)[C@@H]3CC[C@@H](CC3)NC(=O)C=C)c2)n2ncc(C3CC3)c2n1	InChI=1S/C31H40N8O3/c1-3-27(40)34-23-11-9-22(10-12-23)29(41)35-24-6-4-5-20(17-24)18-32-30-37-31(42-25-13-15-38(2)16-14-25)36-28-26(21-7-8-21)19-33-39(28)30/h3-6,17,19,21-23,25H,1,7-16,18H2,2H3,(H,34,40)(H,35,41)(H,32,36,37)/t22-,23+	VDTCFLVQPCODSU-ZRZAMGCNSA-N	526632	(1,4-cis)-4-acrylamido-N-(3-(((8-cyclopropyl-2-((1-methylpiperidin-4-yl)oxy) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 105.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526632&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301331	463790262							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113628	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(CC4)C(=O)C=C)c3)nc(OC3CCNCC3)nc12	InChI=1S/C29H38N8O3/c1-4-25(38)36-14-10-21(11-15-36)27(39)33-22-7-5-6-20(16-22)17-31-28-35-29(40-23-8-12-30-13-9-23)34-26-24(19(2)3)18-32-37(26)28/h4-7,16,18-19,21,23,30H,1,8-15,17H2,2-3H3,(H,33,39)(H,31,34,35)	UIEGCGWZWNFLPV-UHFFFAOYSA-N	526633	(1,4-cis)-4-acrylamido-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 106.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526633&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517844	463790263							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113629	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(CC4)C(=O)C=C)c3)nc(OCCCCN)nc12	InChI=1S/C28H38N8O3/c1-4-24(37)35-13-10-21(11-14-35)26(38)32-22-9-7-8-20(16-22)17-30-27-34-28(39-15-6-5-12-29)33-25-23(19(2)3)18-31-36(25)27/h4,7-9,16,18-19,21H,1,5-6,10-15,17,29H2,2-3H3,(H,32,38)(H,30,33,34)	UJFOUMFEPVUHLH-UHFFFAOYSA-N	526634	1-acryloyl-N-(3-(((2-(4-aminobutoxy)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-4- yl)amino)methyl)phenyl)piperidine-4-carboxamide::US11186576, Compound 107.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526634&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517796	463790264							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113630	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H38N8O3/c1-5-25(38)36-14-9-21(18-36)27(39)32-22-8-6-7-20(15-22)16-30-28-34-29(40-23-10-12-35(4)13-11-23)33-26-24(19(2)3)17-31-37(26)28/h5-8,15,17,19,21,23H,1,9-14,16,18H2,2-4H3,(H,32,39)(H,30,33,34)	LNIAIHWQEDDETK-UHFFFAOYSA-N	526635	1-acryloyl-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::BDBM526636::US11186576, Compound 108.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526635&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517822	463790265							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113631	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H38N8O3/c1-5-25(38)36-14-9-21(18-36)27(39)32-22-8-6-7-20(15-22)16-30-28-34-29(40-23-10-12-35(4)13-11-23)33-26-24(19(2)3)17-31-37(26)28/h5-8,15,17,19,21,23H,1,9-14,16,18H2,2-4H3,(H,32,39)(H,30,33,34)	LNIAIHWQEDDETK-UHFFFAOYSA-N	526635	1-acryloyl-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::BDBM526636::US11186576, Compound 108.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526635&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517822	463790265							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113632	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(C4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H38N8O3/c1-5-25(38)36-14-9-21(18-36)27(39)32-22-8-6-7-20(15-22)16-30-28-34-29(40-23-10-12-35(4)13-11-23)33-26-24(19(2)3)17-31-37(26)28/h5-8,15,17,19,21,23H,1,9-14,16,18H2,2-4H3,(H,32,39)(H,30,33,34)	LNIAIHWQEDDETK-UHFFFAOYSA-N	526635	1-acryloyl-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)pyrrolidine-3-carboxamide::BDBM526636::US11186576, Compound 108.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526635&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517822	463790265							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113633	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN(CC4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C30H40N8O3/c1-5-26(39)37-15-9-22(10-16-37)28(40)33-23-8-6-7-21(17-23)18-31-29-35-30(41-24-11-13-36(4)14-12-24)34-27-25(20(2)3)19-32-38(27)29/h5-8,17,19-20,22,24H,1,9-16,18H2,2-4H3,(H,33,40)(H,31,34,35)	RZLRMJBYKRNXCB-UHFFFAOYSA-N	526638	1-acryloyl-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-4-carboxamide::US11186576, Compound 111.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526638&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517807	463790267							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113634	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CN(CCO4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H38N8O4/c1-5-25(38)36-13-14-40-24(18-36)27(39)32-21-8-6-7-20(15-21)16-30-28-34-29(41-22-9-11-35(4)12-10-22)33-26-23(19(2)3)17-31-37(26)28/h5-8,15,17,19,22,24H,1,9-14,16,18H2,2-4H3,(H,32,39)(H,30,33,34)	VFICZOBNCSVFJY-UHFFFAOYSA-N	526639	4-acryloyl-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)morpholine-2-carboxamide::US11186576, Compound 112.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526639&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517826	463790268							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113635	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4COCCN4C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H38N8O4/c1-5-25(38)36-13-14-40-18-24(36)27(39)32-21-8-6-7-20(15-21)16-30-28-34-29(41-22-9-11-35(4)12-10-22)33-26-23(19(2)3)17-31-37(26)28/h5-8,15,17,19,22,24H,1,9-14,16,18H2,2-4H3,(H,32,39)(H,30,33,34)	QKKPPHZRGIZZEG-UHFFFAOYSA-N	526640	4-acryloyl-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)morpholine-3-carboxamide::US11186576, Compound 113.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526640	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526640&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517753	463790269							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113636	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCC(C4)NC(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C31H42N8O3/c1-5-27(40)34-24-11-7-9-22(17-24)29(41)35-23-10-6-8-21(16-23)18-32-30-37-31(42-25-12-14-38(4)15-13-25)36-28-26(20(2)3)19-33-39(28)30/h5-6,8,10,16,19-20,22,24-25H,1,7,9,11-15,17-18H2,2-4H3,(H,34,40)(H,35,41)(H,32,36,37)	UGFVHZWAOXCEDL-UHFFFAOYSA-N	526641	3-acrylamido-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1-carboxamide::US11186576, Compound 114.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526641&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517815	463790270							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113637	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C31H42N8O3/c1-5-27(40)34-23-11-9-22(10-12-23)29(41)35-24-8-6-7-21(17-24)18-32-30-37-31(42-25-13-15-38(4)16-14-25)36-28-26(20(2)3)19-33-39(28)30/h5-8,17,19-20,22-23,25H,1,9-16,18H2,2-4H3,(H,34,40)(H,35,41)(H,32,36,37)/t22-,23+	RQRWQOCGMQHYHY-ZRZAMGCNSA-N	526642	(1,4-cis)-4-acrylamido-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 115.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526642	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526642&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134301315	463790271							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113638	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCN(C4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C30H40N8O3/c1-5-26(39)37-13-7-9-22(19-37)28(40)33-23-10-6-8-21(16-23)17-31-29-35-30(41-24-11-14-36(4)15-12-24)34-27-25(20(2)3)18-32-38(27)29/h5-6,8,10,16,18,20,22,24H,1,7,9,11-15,17,19H2,2-4H3,(H,33,40)(H,31,34,35)	QHIAVWIHYDEQOE-UHFFFAOYSA-N	526643	1-acryloyl-N-(3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-3-carboxamide::US11186576, Compound 116.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526643	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526643&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517706	463790272							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113639	CC(C)c1cnn2c(NCc3ccc(F)c(NC(=O)C4CCCN(C4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C30H39FN8O3/c1-5-26(40)38-12-6-7-21(18-38)28(41)34-25-15-20(8-9-24(25)31)16-32-29-36-30(42-22-10-13-37(4)14-11-22)35-27-23(19(2)3)17-33-39(27)29/h5,8-9,15,17,19,21-22H,1,6-7,10-14,16,18H2,2-4H3,(H,34,41)(H,32,35,36)	SLHGJQHQOGSKEN-UHFFFAOYSA-N	526644	1-acryloyl-N-(2-fluoro-5-(((8-isopropyl-2-((1-methylpiperidin-4- yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-3- carboxamide::US11186576, Compound 117.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526644&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517825	463790273							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113640	CC(C)c1cnn2c(NCc3ccc(F)c(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C31H41FN8O3/c1-5-27(41)35-22-9-7-21(8-10-22)29(42)36-26-16-20(6-11-25(26)32)17-33-30-38-31(43-23-12-14-39(4)15-13-23)37-28-24(19(2)3)18-34-40(28)30/h5-6,11,16,18-19,21-23H,1,7-10,12-15,17H2,2-4H3,(H,35,41)(H,36,42)(H,33,37,38)/t21-,22+	DPRQKCILWAVXND-SZPZYZBQSA-N	526645	(1,4-cis)-4-acrylamido-N-(2-fluoro-5-(((8-isopropyl-2-((1-methylpiperidin-4- yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)cyclohexane-1- carboxamide::US11186576, Compound 118.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526645	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526645&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536801	463790274							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113641	CC(C)c1cnn2c(NC(C)c3cccc(NC(=O)C4CCCN(C4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C31H42N8O3/c1-6-27(40)38-14-8-10-23(19-38)29(41)34-24-11-7-9-22(17-24)21(4)33-30-36-31(42-25-12-15-37(5)16-13-25)35-28-26(20(2)3)18-32-39(28)30/h6-7,9,11,17-18,20-21,23,25H,1,8,10,12-16,19H2,2-5H3,(H,34,41)(H,33,35,36)	CYRINMBGDBJVJW-UHFFFAOYSA-N	526646	1-acryloyl-N-(3-(1-((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)ethyl)phenyl)piperidine-3-carboxamide::US11186576, Compound 119.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526646&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517742	463790275							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113642	CC(C)c1cnn2c(NCc3ccc(NC(=O)C4CCCN(C4)C(=O)C=C)[n+]([O-])c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H39N9O4/c1-5-25(39)36-12-6-7-21(18-36)27(40)32-24-9-8-20(17-37(24)41)15-30-28-34-29(42-22-10-13-35(4)14-11-22)33-26-23(19(2)3)16-31-38(26)28/h5,8-9,16-17,19,21-22H,1,6-7,10-15,18H2,2-4H3,(H,32,40)(H,30,33,34)	IGDVZJCOHDCHLD-UHFFFAOYSA-N	526647	2-(1-acryloylpiperidine-3-carboxamido)-5-(((8-isopropyl-2-((1-methylpiperidin-4- yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)pyridine 1-oxide::US11186576, Compound 120.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526647&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517868	463790276							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113643	CC(C)c1cnn2c(NCc3cccc(OC(=O)N4CCN(CC4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H38N8O4/c1-5-25(38)35-13-15-36(16-14-35)29(39)41-23-8-6-7-21(17-23)18-30-27-33-28(40-22-9-11-34(4)12-10-22)32-26-24(20(2)3)19-31-37(26)27/h5-8,17,19-20,22H,1,9-16,18H2,2-4H3,(H,30,32,33)	AXVAQKAMTJOVSB-UHFFFAOYSA-N	526648	3-(((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4- yl)amino)methyl)phenyl 4-acryloylpiperazine-1-carboxylate::US11186576, Compound 121.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526648&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517833	463790277							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113644	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCCN(C4)C(=O)\C=C\CN(C)C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C33H47N9O3/c1-23(2)28-21-35-42-30(28)37-33(45-27-13-17-40(5)18-14-27)38-32(42)34-20-24-9-6-11-26(19-24)36-31(44)25-10-7-16-41(22-25)29(43)12-8-15-39(3)4/h6,8-9,11-12,19,21,23,25,27H,7,10,13-18,20,22H2,1-5H3,(H,36,44)(H,34,37,38)/b12-8+	IZTBLRSILOHFQO-XYOKQWHBSA-N	526649	(E)-1-(4-(dimethylamino)but-2-enoyl)-N-(3-(((8-isopropyl-2-((1-methylpiperidin- 4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperidine-3- carboxamide::US11186576, Compound 122.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526649	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526649&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517743	463790278							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113645	CC(C)c1cnn2c(NCc3ccc(F)c(NC(=O)C4CCCN(C4)C(=O)\C=C\CN(C)C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C33H46FN9O3/c1-22(2)26-20-36-43-30(26)38-33(46-25-12-16-41(5)17-13-25)39-32(43)35-19-23-10-11-27(34)28(18-23)37-31(45)24-8-6-15-42(21-24)29(44)9-7-14-40(3)4/h7,9-11,18,20,22,24-25H,6,8,12-17,19,21H2,1-5H3,(H,37,45)(H,35,38,39)/b9-7+	FFEZCKWOICBOIM-VQHVLOKHSA-N	526650	(E)-1-(4-(dimethylamino)but-2-enoyl)-N-(2-fluoro-5-(((8-isopropyl-2-((1- methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl) phenyl)piperidine-3-carboxamide::US11186576, Compound 123.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526650&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536947	463790279							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113646	CC(C)c1cnn2c(NCc3ccc(F)c(NC(=O)[C@@H]4CC[C@@H](CC4)NC(=O)\C=C\CN(C)C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C34H48FN9O3/c1-22(2)27-21-37-44-31(27)40-34(47-26-14-17-43(5)18-15-26)41-33(44)36-20-23-8-13-28(35)29(19-23)39-32(46)24-9-11-25(12-10-24)38-30(45)7-6-16-42(3)4/h6-8,13,19,21-22,24-26H,9-12,14-18,20H2,1-5H3,(H,38,45)(H,39,46)(H,36,40,41)/b7-6+/t24-,25+	XABXKICVONGRAL-DEKMAOODSA-N	526651	(1,4-cis)-4-((E)-4-(dimethylamino)but-2-enamido)-N-(2-fluoro-5-(((8-isopropyl- 2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl) phenyl)cyclohexane-1-carboxamide::US11186576, Compound 124.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526651&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536946	463790280							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113647	CC(C)c1cnn2c(Nc3cccc(NC(=O)c4ccc(NC(=O)C=C)cc4)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C30H34N8O3/c1-5-26(39)32-21-11-9-20(10-12-21)28(40)33-22-7-6-8-23(17-22)34-29-36-30(41-24-13-15-37(4)16-14-24)35-27-25(19(2)3)18-31-38(27)29/h5-12,17-19,24H,1,13-16H2,2-4H3,(H,32,39)(H,33,40)(H,34,35,36)	POKPJQCGBWWRNF-UHFFFAOYSA-N	526652	4-acrylamido-N-(3-((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)phenyl)benzamide::US11186576, Compound 125.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526652	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526652&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517791	463790281							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113648	CC(C)c1cnn2c(Nc3cccc(NC(=O)C4CC[C@@H](CC4)NC(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C30H40N8O3/c1-5-26(39)32-21-11-9-20(10-12-21)28(40)33-22-7-6-8-23(17-22)34-29-36-30(41-24-13-15-37(4)16-14-24)35-27-25(19(2)3)18-31-38(27)29/h5-8,17-21,24H,1,9-16H2,2-4H3,(H,32,39)(H,33,40)(H,34,35,36)/t20?,21-	XBTMRUWGUMUPAK-UPDYAAQLSA-N	526653	(1,4-cis)-4-acrylamido-N-(3-((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)phenyl)cyclohexane-1-carboxamide::US11186576, Compound 126.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526653&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			134295957	463790282							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113649	CC(C)c1cnn2c(Nc3cccc(NC(=O)C4CCN(CC4)C(=O)C=C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H38N8O3/c1-5-25(38)36-15-9-20(10-16-36)27(39)31-21-7-6-8-22(17-21)32-28-34-29(40-23-11-13-35(4)14-12-23)33-26-24(19(2)3)18-30-37(26)28/h5-8,17-20,23H,1,9-16H2,2-4H3,(H,31,39)(H,32,33,34)	MONNGBJQTILSJS-UHFFFAOYSA-N	526654	1-acryloyl-N-(3-((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)phenyl)piperidine-4-carboxamide::US11186576, Compound 127.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526654&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517767	463790283							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1109901	CCc1cc(NC(=O)C(C)c2cccc(c2)-c2ccc(NC(=O)\C=C\CN(C)C)cc2)n[nH]1			525330	US11174232, Compound 8	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>100							US Patent		10.7270/Q2W66PXD		aid1806097	US11174232	Samajdar, S; Poddutoori, R; Pandit, C; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=525330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=525330&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			124118344	463788996							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113650	CC(C)c1cnn2c(Nc3cccc(c3)C(=O)NC3CCN(CC3)C(=O)C=C)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H38N8O3/c1-5-25(38)36-15-9-21(10-16-36)31-27(39)20-7-6-8-22(17-20)32-28-34-29(40-23-11-13-35(4)14-12-23)33-26-24(19(2)3)18-30-37(26)28/h5-8,17-19,21,23H,1,9-16H2,2-4H3,(H,31,39)(H,32,33,34)	YDDYNUGTRZIDBE-UHFFFAOYSA-N	526655	N-(1-acryloylpiperidin-4-yl)-3-((8-isopropyl-2-((1-methylpiperidin-4- yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)benzamide::US11186576, Compound 128.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526655&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517799	463790284							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113651	CC(C)c1cnn2c(Nc3cccc(c3)C(=O)NC3CCCN(C3)C(=O)C=C)nc(OC3CCN(C)CC3)nc12	InChI=1S/C29H38N8O3/c1-5-25(38)36-13-7-10-22(18-36)31-27(39)20-8-6-9-21(16-20)32-28-34-29(40-23-11-14-35(4)15-12-23)33-26-24(19(2)3)17-30-37(26)28/h5-6,8-9,16-17,19,22-23H,1,7,10-15,18H2,2-4H3,(H,31,39)(H,32,33,34)	JCNQXQROULXZKW-UHFFFAOYSA-N	526656	N-(1-acryloylpiperidin-3-yl)-3-((8-isopropyl-2-((1-methylpiperidin-4-yl)oxy) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)benzamide::US11186576, Compound 129.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526656	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526656&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517803	463790285							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113652	CC(C)c1cnn2c(Nc3cccc(NC(=O)c4ccc(NC(=O)\C=C\CN(C)C)cc4)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C33H41N9O3/c1-22(2)28-21-34-42-30(28)38-33(45-27-15-18-41(5)19-16-27)39-32(42)37-26-9-6-8-25(20-26)36-31(44)23-11-13-24(14-12-23)35-29(43)10-7-17-40(3)4/h6-14,20-22,27H,15-19H2,1-5H3,(H,35,43)(H,36,44)(H,37,38,39)/b10-7+	SZJVGVAOKDTNEX-JXMROGBWSA-N	526657	(E)-4-(4-(dimethylamino)but-2-enamido)-N-(3-((8-isopropyl-2-((1-methyl piperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)phenyl)benzamide::US11186576, Compound 130.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526657	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526657&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517712	463790286							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113653	CC(C)c1cnn2c(Nc3cccc(NC(=O)C4CC[C@@H](CC4)NC(=O)\C=C\CN(C)C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C33H47N9O3/c1-22(2)28-21-34-42-30(28)38-33(45-27-15-18-41(5)19-16-27)39-32(42)37-26-9-6-8-25(20-26)36-31(44)23-11-13-24(14-12-23)35-29(43)10-7-17-40(3)4/h6-10,20-24,27H,11-19H2,1-5H3,(H,35,43)(H,36,44)(H,37,38,39)/b10-7+/t23?,24-	LFQSGWPPJFRUFY-DUMWHECDSA-N	526658	(1,4-cis)-4-((E)-4-(dimethylamino)but-2-enamido)-N-(3-((8-isopropyl-2-((1- methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)phenyl) cyclohexane-1-carboxamide::US11186576, Compound 131.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526658	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526658&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536807	463790287							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113654	CC(C)c1cnn2c(Nc3cccc(NC(=O)[C@H]4CC[C@@H](CC4)NC(=O)\C=C\CN(C)C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C33H47N9O3/c1-22(2)28-21-34-42-30(28)38-33(45-27-15-18-41(5)19-16-27)39-32(42)37-26-9-6-8-25(20-26)36-31(44)23-11-13-24(14-12-23)35-29(43)10-7-17-40(3)4/h6-10,20-24,27H,11-19H2,1-5H3,(H,35,43)(H,36,44)(H,37,38,39)/b10-7+/t23-,24-	LFQSGWPPJFRUFY-MEQJCYJFSA-N	526659	(1,4-Trans)-4-((E)-4-(dimethylamino)but-2-enamido)-N-(3-((8-isopropyl-2-((1- methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)phenyl) cyclohexane-1-carboxamide::US11186576, Compound 132.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526659	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526659&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536807	463790288							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113655	CC(C)c1cnn2c(Nc3cccc(c3)C(=O)NC3CCCN(C3)C(=O)\C=C\CN(C)C)nc(OC3CCN(C)CC3)nc12	InChI=1S/C32H45N9O3/c1-22(2)27-20-33-41-29(27)36-32(44-26-13-17-39(5)18-14-26)37-31(41)35-24-10-6-9-23(19-24)30(43)34-25-11-7-16-40(21-25)28(42)12-8-15-38(3)4/h6,8-10,12,19-20,22,25-26H,7,11,13-18,21H2,1-5H3,(H,34,43)(H,35,36,37)/b12-8+	RAVLDMFNKTVLSG-XYOKQWHBSA-N	526660	(E)-N-(1-(4-(dimethylamino)but-2-enoyl)piperidin-3-yl)-3-((8-isopropyl-2-((1- methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)benzamide::US11186576, Compound 133.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526660	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526660&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517876	463790289							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113656	CC(C)c1cnn2c(Nc3cccc(c3)C(=O)NC3CCN(CC3)C(=O)\C=C\CN(C)C)nc(OC3CCN(C)CC3)nc12	InChI=1S/C32H45N9O3/c1-22(2)27-21-33-41-29(27)36-32(44-26-13-16-39(5)17-14-26)37-31(41)35-25-9-6-8-23(20-25)30(43)34-24-11-18-40(19-12-24)28(42)10-7-15-38(3)4/h6-10,20-22,24,26H,11-19H2,1-5H3,(H,34,43)(H,35,36,37)/b10-7+	NZNJJDBKESALQA-JXMROGBWSA-N	526661	(E)-N-(1-(4-(dimethylamino)but-2-enoyl)piperidin-4-yl)-3-((8-isopropyl-2-((1- methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)benzamide::US11186576, Compound 134.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526661	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526661&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517756	463790290							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113657	CC(C)c1cnn2c(NCc3cccc(NC(=O)[C@@H]4CC[C@@H](CC4)NC\C=C\C(=O)N(C)C)c3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C34H49N9O3/c1-23(2)29-22-37-43-31(29)39-34(46-28-15-18-42(5)19-16-28)40-33(43)36-21-24-8-6-9-27(20-24)38-32(45)25-11-13-26(14-12-25)35-17-7-10-30(44)41(3)4/h6-10,20,22-23,25-26,28,35H,11-19,21H2,1-5H3,(H,38,45)(H,36,39,40)/b10-7+/t25-,26+	VDLQREYGEVBDMV-NIOBQARGSA-N	526662	(1,4-cis)-4-(((E)-4-(dimethylamino)-4-oxobut-2-en-1-yl)amino)-N-(3-(((8- isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4- yl)amino)methyl)phenyl)cyclohexane-1-carboxamide::US11186576, Compound 135.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526662	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526662&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536991	463790291							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113658	COc1nc(NCc2cccc(NC(=O)C3CCN(CC3)C(=O)C=C)c2)n2ncc(C(C)C)c2n1	InChI=1S/C25H31N7O3/c1-5-21(33)31-11-9-18(10-12-31)23(34)28-19-8-6-7-17(13-19)14-26-24-30-25(35-4)29-22-20(16(2)3)15-27-32(22)24/h5-8,13,15-16,18H,1,9-12,14H2,2-4H3,(H,28,34)(H,26,29,30)	ZSEPOSLDBYTTOP-UHFFFAOYSA-N	526663	1-acryloyl-N-(3-(((8-isopropyl-2-methoxypyrazolo[1,5-a][1,3,5]triazin-4-yl) amino)methyl)phenyl)piperidine-4-carboxamide::US11186576, Compound 136.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526663&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517783	463790292							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113659	CC(C)c1cnn2c(NCc3ccccc3N3CCN(CC3)C(=O)\C=C\CN(C)C)nc(NC3CCOCC3)nc12	InChI=1S/C30H43N9O2/c1-22(2)25-21-32-39-28(25)34-29(33-24-11-18-41-19-12-24)35-30(39)31-20-23-8-5-6-9-26(23)37-14-16-38(17-15-37)27(40)10-7-13-36(3)4/h5-10,21-22,24H,11-20H2,1-4H3,(H2,31,33,34,35)/b10-7+	OGKOQPPQOGSRML-JXMROGBWSA-N	526664	(E)-4-(dimethylamino)-1-(4-(2-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl) amino)pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)piperazin-1-yl)but- 2-en-1-one::US11186576, Compound 137.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526664&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517757	463790293							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113660	CC(C)c1cnn2c(NCC3CCN(CC3)C(=O)\C=C\CN3CCCC3)nc(NC3CCOCC3)nc12	InChI=1S/C27H42N8O2/c1-20(2)23-19-29-35-25(23)31-26(30-22-9-16-37-17-10-22)32-27(35)28-18-21-7-14-34(15-8-21)24(36)6-5-13-33-11-3-4-12-33/h5-6,19-22H,3-4,7-18H2,1-2H3,(H2,28,30,31,32)/b6-5+	DSFZZUGNNOOUNN-AATRIKPKSA-N	526665	(E)-1-(4-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5-a] [1,3,5]triazin-4-yl)amino)methyl)piperidin-1-yl)-4-(pyrrolidin-1-yl)but-2-en-1- one::US11186576, Compound 138.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526665&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517770	463790294							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113661	CC(C)c1cnn2c(NCc3cccc(NC(=O)C4CCN4C(=O)C=C)c3)cc(NC3CCOCC3)nc12	InChI=1S/C28H35N7O3/c1-4-26(36)34-11-8-23(34)28(37)32-21-7-5-6-19(14-21)16-29-25-15-24(31-20-9-12-38-13-10-20)33-27-22(18(2)3)17-30-35(25)27/h4-7,14-15,17-18,20,23,29H,1,8-13,16H2,2-3H3,(H,31,33)(H,32,37)	OPJYPQHGSWFBRW-UHFFFAOYSA-N	526666	1-acryloyl-N-(3-(((3-isopropyl-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a]pyrimidin-7-yl)amino)methyl)phenyl)azetidine-2-carboxamide::US11186576, Compound 139.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526666	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526666&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517863	463790295							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113662	CC(C)c1cnn2c(NCc3cncc(NC(=O)C4COCCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H35N9O4/c1-4-23(37)35-7-10-40-16-22(35)25(38)31-20-11-18(12-28-14-20)13-29-27-34-26(32-19-5-8-39-9-6-19)33-24-21(17(2)3)15-30-36(24)27/h4,11-12,14-15,17,19,22H,1,5-10,13,16H2,2-3H3,(H,31,38)(H2,29,32,33,34)	TYZQGXYAWLLTSU-UHFFFAOYSA-N	526570	4-acryloyl-N-(5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)pyridin-3-yl)morpholine-3-carboxamide::US11186576, Compound 40.::US11186576, Compound 40A.::US11186576, Compound 40B.::US11186576, Compound 40C.::US11186576, Compound 40D.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526570&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536988	463790202							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113663	CC(C)c1cnn2c(NCc3cncc(NC(=O)C4COCCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H35N9O4/c1-4-23(37)35-7-10-40-16-22(35)25(38)31-20-11-18(12-28-14-20)13-29-27-34-26(32-19-5-8-39-9-6-19)33-24-21(17(2)3)15-30-36(24)27/h4,11-12,14-15,17,19,22H,1,5-10,13,16H2,2-3H3,(H,31,38)(H2,29,32,33,34)	TYZQGXYAWLLTSU-UHFFFAOYSA-N	526570	4-acryloyl-N-(5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)pyridin-3-yl)morpholine-3-carboxamide::US11186576, Compound 40.::US11186576, Compound 40A.::US11186576, Compound 40B.::US11186576, Compound 40C.::US11186576, Compound 40D.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526570&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536988	463790202							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113664	CC(C)c1cnn2c(NCc3cncc(NC(=O)C4COCCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H35N9O4/c1-4-23(37)35-7-10-40-16-22(35)25(38)31-20-11-18(12-28-14-20)13-29-27-34-26(32-19-5-8-39-9-6-19)33-24-21(17(2)3)15-30-36(24)27/h4,11-12,14-15,17,19,22H,1,5-10,13,16H2,2-3H3,(H,31,38)(H2,29,32,33,34)	TYZQGXYAWLLTSU-UHFFFAOYSA-N	526570	4-acryloyl-N-(5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)pyridin-3-yl)morpholine-3-carboxamide::US11186576, Compound 40.::US11186576, Compound 40A.::US11186576, Compound 40B.::US11186576, Compound 40C.::US11186576, Compound 40D.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526570&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536988	463790202							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113665	CC(C)c1cnn2c(NCc3cncc(NC(=O)C4COCCN4C(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C27H35N9O4/c1-4-23(37)35-7-10-40-16-22(35)25(38)31-20-11-18(12-28-14-20)13-29-27-34-26(32-19-5-8-39-9-6-19)33-24-21(17(2)3)15-30-36(24)27/h4,11-12,14-15,17,19,22H,1,5-10,13,16H2,2-3H3,(H,31,38)(H2,29,32,33,34)	TYZQGXYAWLLTSU-UHFFFAOYSA-N	526570	4-acryloyl-N-(5-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino)pyrazolo[1,5- a][1,3,5]triazin-4-yl)amino)methyl)pyridin-3-yl)morpholine-3-carboxamide::US11186576, Compound 40.::US11186576, Compound 40A.::US11186576, Compound 40B.::US11186576, Compound 40C.::US11186576, Compound 40D.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 650							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526570&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122536988	463790202							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1113666	CC(C)c1cnn2c(NCc3cccc(NC(=O)c4ccccc4NC(=O)C=C)c3)nc(NC3CCOCC3)nc12	InChI=1S/C30H34N8O3/c1-4-26(39)35-25-11-6-5-10-23(25)28(40)33-22-9-7-8-20(16-22)17-31-30-37-29(34-21-12-14-41-15-13-21)36-27-24(19(2)3)18-32-38(27)30/h4-11,16,18-19,21H,1,12-15,17H2,2-3H3,(H,33,40)(H,35,39)(H2,31,34,36,37)	WXYJBUJBMFEFAX-UHFFFAOYSA-N	526578	2-acrylamido-N-(3-(((8-isopropyl-2-((tetrahydro-2H-pyran-4-yl)amino) pyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)methyl)phenyl)benzamide::US11186576, Compound 48.::US11186576, Compound 48A.	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<300							US Patent		10.7270/Q2Z03CCX		aid1806127	US11186576	Samajdar, S; Poddutoori, R; Mukherjee, S; Goswami, R	Aurigene Discovery Technologies Limited	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=526578	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=526578&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			122517746	463790210							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121064	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H33N7O/c1-18-13-20-14-27-26(28-15-21-9-12-32(3)30-21)29-24(20)17-33(18)25(34)22-10-11-31(2)16-23(22)19-7-5-4-6-8-19/h4-9,12,14,18,22-23H,10-11,13,15-17H2,1-3H3,(H,27,28,29)/t18-,22+,23-/m1/s1	KLUZOYLPHBNTLS-YFXJRYMSSA-N	530245	WO2022064009, Compound 1::WO2022064009, Compound 51	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530245&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200189	463793736							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121065	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H33N7O/c1-18-13-20-14-27-26(28-15-21-9-12-32(3)30-21)29-24(20)17-33(18)25(34)22-10-11-31(2)16-23(22)19-7-5-4-6-8-19/h4-9,12,14,18,22-23H,10-11,13,15-17H2,1-3H3,(H,27,28,29)/t18-,22+,23-/m1/s1	KLUZOYLPHBNTLS-YFXJRYMSSA-N	530245	WO2022064009, Compound 1::WO2022064009, Compound 51	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.45							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530245&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200189	463793736							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121066	C[C@@H]1Cc2cnc(NCc3ccn(CC(C)(C)O)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H39N7O2/c1-20-14-22-15-30-28(31-16-23-10-13-35(33-23)19-29(2,3)38)32-26(22)18-36(20)27(37)24-11-12-34(4)17-25(24)21-8-6-5-7-9-21/h5-10,13,15,20,24-25,38H,11-12,14,16-19H2,1-4H3,(H,30,31,32)/t20-,24+,25-/m1/s1	AYYCEWLBJJGEEP-DCEDVJGZSA-N	530246	WO2022064009, Compound 2	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 19							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530246&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200190	463793737							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121067	C[C@@H]1Cc2cnc(NCc3ccn(CC(C)(C)O)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H39N7O2/c1-20-14-22-15-30-28(31-16-23-10-13-35(33-23)19-29(2,3)38)32-26(22)18-36(20)27(37)24-11-12-34(4)17-25(24)21-8-6-5-7-9-21/h5-10,13,15,20,24-25,38H,11-12,14,16-19H2,1-4H3,(H,30,31,32)/t20-,24+,25-/m1/s1	AYYCEWLBJJGEEP-DCEDVJGZSA-N	530246	WO2022064009, Compound 2	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 10.00							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530246&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200190	463793737							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121068	C[C@@H]1Cc2cnc(NC3CC[C@@H](CC3)OCC3CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C31H43N5O2/c1-21-16-24-17-32-31(33-25-10-12-26(13-11-25)38-20-22-8-9-22)34-29(24)19-36(21)30(37)27-14-15-35(2)18-28(27)23-6-4-3-5-7-23/h3-7,17,21-22,25-28H,8-16,18-20H2,1-2H3,(H,32,33,34)/t21-,25?,26-,27+,28-/m1/s1	PZTCHBKEJNASPY-GGKBYBOBSA-N	530247	WO2022064009, Compound 3	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530247&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200191	463793738							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121069	C[C@@H]1Cc2cnc(NC3CC[C@@H](CC3)OCC3CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C31H43N5O2/c1-21-16-24-17-32-31(33-25-10-12-26(13-11-25)38-20-22-8-9-22)34-29(24)19-36(21)30(37)27-14-15-35(2)18-28(27)23-6-4-3-5-7-23/h3-7,17,21-22,25-28H,8-16,18-20H2,1-2H3,(H,32,33,34)/t21-,25?,26-,27+,28-/m1/s1	PZTCHBKEJNASPY-GGKBYBOBSA-N	530247	WO2022064009, Compound 3	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5.01							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530247&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200191	463793738							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121070	C[C@@H]1Cc2cnc(N[C@@H]3CCN(C)C(=O)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H36N6O2/c1-18-13-20-15-28-27(29-21-9-12-32(3)25(34)14-21)30-24(20)17-33(18)26(35)22-10-11-31(2)16-23(22)19-7-5-4-6-8-19/h4-8,15,18,21-23H,9-14,16-17H2,1-3H3,(H,28,29,30)/t18-,21-,22+,23-/m1/s1	HMWQKGSYBLBYCZ-TWHAJKEOSA-N	530248	WO2022064009, Compound 4	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 35							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530248&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200192	463793739							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121071	C[C@@H]1Cc2cnc(N[C@H]3CCN(C)C(=O)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H36N6O2/c1-18-13-20-15-28-27(29-21-9-12-32(3)25(34)14-21)30-24(20)17-33(18)26(35)22-10-11-31(2)16-23(22)19-7-5-4-6-8-19/h4-8,15,18,21-23H,9-14,16-17H2,1-3H3,(H,28,29,30)/t18-,21+,22+,23-/m1/s1	HMWQKGSYBLBYCZ-HGSOSGBHSA-N	530249	WO2022064009, Compound 5	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530249&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200193	463793740							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121072	C[C@@H]1Cc2cnc(N[C@H]3CCN(C)C(=O)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H36N6O2/c1-18-13-20-15-28-27(29-21-9-12-32(3)25(34)14-21)30-24(20)17-33(18)26(35)22-10-11-31(2)16-23(22)19-7-5-4-6-8-19/h4-8,15,18,21-23H,9-14,16-17H2,1-3H3,(H,28,29,30)/t18-,21+,22+,23-/m1/s1	HMWQKGSYBLBYCZ-HGSOSGBHSA-N	530249	WO2022064009, Compound 5	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.14							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530249&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200193	463793740							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121073	C[C@@H]1Cc2cnc(N[C@@H]3CCC(=O)N(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H36N6O2/c1-18-13-20-14-28-27(29-21-9-10-25(34)32(3)15-21)30-24(20)17-33(18)26(35)22-11-12-31(2)16-23(22)19-7-5-4-6-8-19/h4-8,14,18,21-23H,9-13,15-17H2,1-3H3,(H,28,29,30)/t18-,21-,22+,23-/m1/s1	INDKHCOGEZGYQF-TWHAJKEOSA-N	530250	WO2022064009, Compound 6	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530250&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200194	463793741							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121074	C[C@@H]1Cc2cnc(N[C@@H]3CCC(=O)N(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H36N6O2/c1-18-13-20-14-28-27(29-21-9-10-25(34)32(3)15-21)30-24(20)17-33(18)26(35)22-11-12-31(2)16-23(22)19-7-5-4-6-8-19/h4-8,14,18,21-23H,9-13,15-17H2,1-3H3,(H,28,29,30)/t18-,21-,22+,23-/m1/s1	INDKHCOGEZGYQF-TWHAJKEOSA-N	530250	WO2022064009, Compound 6	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.80							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530250&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200194	463793741							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121075	C[C@@H]1Cc2cnc(N[C@H]3CCC(=O)N(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H36N6O2/c1-18-13-20-14-28-27(29-21-9-10-25(34)32(3)15-21)30-24(20)17-33(18)26(35)22-11-12-31(2)16-23(22)19-7-5-4-6-8-19/h4-8,14,18,21-23H,9-13,15-17H2,1-3H3,(H,28,29,30)/t18-,21+,22+,23-/m1/s1	INDKHCOGEZGYQF-HGSOSGBHSA-N	530251	WO2022064009, Compound 7	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530251&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200195	463793742							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121076	C[C@@H]1Cc2cnc(N[C@H]3CCC(=O)N(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H36N6O2/c1-18-13-20-14-28-27(29-21-9-10-25(34)32(3)15-21)30-24(20)17-33(18)26(35)22-11-12-31(2)16-23(22)19-7-5-4-6-8-19/h4-8,14,18,21-23H,9-13,15-17H2,1-3H3,(H,28,29,30)/t18-,21+,22+,23-/m1/s1	INDKHCOGEZGYQF-HGSOSGBHSA-N	530251	WO2022064009, Compound 7	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 4.47							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530251	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530251&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200195	463793742							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121077	C[C@@H]1Cc2cnc(N[C@@H]3CCOC4(CCC4)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H39N5O2/c1-20-15-22-17-30-28(31-23-10-14-36-29(16-23)11-6-12-29)32-26(22)19-34(20)27(35)24-9-13-33(2)18-25(24)21-7-4-3-5-8-21/h3-5,7-8,17,20,23-25H,6,9-16,18-19H2,1-2H3,(H,30,31,32)/t20-,23-,24+,25-/m1/s1	KMJBCYBYLXHVMU-ZBCONREDSA-N	530252	WO2022064009, Compound 8	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530252&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200196	463793743							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121078	C[C@@H]1Cc2cnc(N[C@@H]3CCOC4(CCC4)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H39N5O2/c1-20-15-22-17-30-28(31-23-10-14-36-29(16-23)11-6-12-29)32-26(22)19-34(20)27(35)24-9-13-33(2)18-25(24)21-7-4-3-5-8-21/h3-5,7-8,17,20,23-25H,6,9-16,18-19H2,1-2H3,(H,30,31,32)/t20-,23-,24+,25-/m1/s1	KMJBCYBYLXHVMU-ZBCONREDSA-N	530252	WO2022064009, Compound 8	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.69							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530252&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200196	463793743							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121079	C[C@@H]1Cc2cnc(N[C@H]3CCOC4(CCC4)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H39N5O2/c1-20-15-22-17-30-28(31-23-10-14-36-29(16-23)11-6-12-29)32-26(22)19-34(20)27(35)24-9-13-33(2)18-25(24)21-7-4-3-5-8-21/h3-5,7-8,17,20,23-25H,6,9-16,18-19H2,1-2H3,(H,30,31,32)/t20-,23+,24+,25-/m1/s1	KMJBCYBYLXHVMU-AKAGGGOCSA-N	530253	WO2022064009, Compound 9	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530253&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200197	463793744							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121080	C[C@@H]1Cc2cnc(N[C@H]3CCOC4(CCC4)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H39N5O2/c1-20-15-22-17-30-28(31-23-10-14-36-29(16-23)11-6-12-29)32-26(22)19-34(20)27(35)24-9-13-33(2)18-25(24)21-7-4-3-5-8-21/h3-5,7-8,17,20,23-25H,6,9-16,18-19H2,1-2H3,(H,30,31,32)/t20-,23+,24+,25-/m1/s1	KMJBCYBYLXHVMU-AKAGGGOCSA-N	530253	WO2022064009, Compound 9	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.17							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530253&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200197	463793744							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121081	CO[C@@]1(C)CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H41N5O2/c1-20-16-22-17-30-28(31-23-10-13-29(2,36-4)14-11-23)32-26(22)19-34(20)27(35)24-12-15-33(3)18-25(24)21-8-6-5-7-9-21/h5-9,17,20,23-25H,10-16,18-19H2,1-4H3,(H,30,31,32)/t20-,23-,24+,25-,29-/m1/s1	HFWZGDMOOPJCDO-RMOVSUMHSA-N	530254	WO2022064009, Compound 10::WO2022064009, Compound 11	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530254&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200198	463793745							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121082	CO[C@@]1(C)CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H41N5O2/c1-20-16-22-17-30-28(31-23-10-13-29(2,36-4)14-11-23)32-26(22)19-34(20)27(35)24-12-15-33(3)18-25(24)21-8-6-5-7-9-21/h5-9,17,20,23-25H,10-16,18-19H2,1-4H3,(H,30,31,32)/t20-,23-,24+,25-,29-/m1/s1	HFWZGDMOOPJCDO-RMOVSUMHSA-N	530254	WO2022064009, Compound 10::WO2022064009, Compound 11	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 7.76							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530254&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200198	463793745							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121083	CO[C@@]1(C)CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H41N5O2/c1-20-16-22-17-30-28(31-23-10-13-29(2,36-4)14-11-23)32-26(22)19-34(20)27(35)24-12-15-33(3)18-25(24)21-8-6-5-7-9-21/h5-9,17,20,23-25H,10-16,18-19H2,1-4H3,(H,30,31,32)/t20-,23-,24+,25-,29-/m1/s1	HFWZGDMOOPJCDO-RMOVSUMHSA-N	530254	WO2022064009, Compound 10::WO2022064009, Compound 11	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 14							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530254	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530254&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200198	463793745							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121084	C[C@@H]1Cc2cnc(N[C@H]3CC[C@H](O)CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-14-20-15-28-27(29-21-8-10-22(33)11-9-21)30-25(20)17-32(18)26(34)23-12-13-31(2)16-24(23)19-6-4-3-5-7-19/h3-7,15,18,21-24,33H,8-14,16-17H2,1-2H3,(H,28,29,30)/t18-,21-,22-,23+,24-/m1/s1	UTFSUZUKVUIUPU-XNZCMHNBSA-N	530256	WO2022064009, Compound 12	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530256&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200199	463793746							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121085	C[C@@H]1Cc2cnc(N[C@H]3CC[C@H](O)CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-14-20-15-28-27(29-21-8-10-22(33)11-9-21)30-25(20)17-32(18)26(34)23-12-13-31(2)16-24(23)19-6-4-3-5-7-19/h3-7,15,18,21-24,33H,8-14,16-17H2,1-2H3,(H,28,29,30)/t18-,21-,22-,23+,24-/m1/s1	UTFSUZUKVUIUPU-XNZCMHNBSA-N	530256	WO2022064009, Compound 12	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.24							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530256	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530256&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200199	463793746							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121086	C[C@@H]1Cc2cnc(NCC3CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H33N5O/c1-17-12-20-14-27-25(26-13-18-8-9-18)28-23(20)16-30(17)24(31)21-10-11-29(2)15-22(21)19-6-4-3-5-7-19/h3-7,14,17-18,21-22H,8-13,15-16H2,1-2H3,(H,26,27,28)/t17-,21+,22-/m1/s1	CEADLRSVHZOHBU-VOQZNFBZSA-N	530257	WO2022064009, Compound 34	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530257	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530257&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200200	463793747							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121087	C[C@@H]1Cc2cnc(NCc3ccccn3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H32N6O/c1-19-14-21-15-29-27(30-16-22-10-6-7-12-28-22)31-25(21)18-33(19)26(34)23-11-13-32(2)17-24(23)20-8-4-3-5-9-20/h3-10,12,15,19,23-24H,11,13-14,16-18H2,1-2H3,(H,29,30,31)/t19-,23+,24-/m1/s1	RCURNUWXLPJMCR-VEXUSMLFSA-N	530258	WO2022064009, Compound 35	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 17							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530258	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530258&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200201	463793748							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121088	C[C@@H]1Cc2cnc(NCC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-19-14-22-16-29-27(28-15-20-9-12-34-13-10-20)30-25(22)18-32(19)26(33)23-8-11-31(2)17-24(23)21-6-4-3-5-7-21/h3-7,16,19-20,23-24H,8-15,17-18H2,1-2H3,(H,28,29,30)/t19-,23+,24-/m1/s1	FXIANAXAVWGMBL-VEXUSMLFSA-N	530259	WO2022064009, Compound 36	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530259&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200202	463793749							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121089	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O2/c1-19-15-21-16-29-28(30-22-9-11-23(35-3)12-10-22)31-26(21)18-33(19)27(34)24-13-14-32(2)17-25(24)20-7-5-4-6-8-20/h4-8,16,19,22-25H,9-15,17-18H2,1-3H3,(H,29,30,31)/t19-,22-,23-,24+,25-/m1/s1	TXYGAIXPPILEQF-WAKWQXKPSA-N	530260	WO2022064009, Compound 37	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530260&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200203	463793750							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121090	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O2/c1-19-15-21-16-29-28(30-22-9-11-23(35-3)12-10-22)31-26(21)18-33(19)27(34)24-13-14-32(2)17-25(24)20-7-5-4-6-8-20/h4-8,16,19,22-25H,9-15,17-18H2,1-3H3,(H,29,30,31)/t19-,22-,23-,24+,25-/m1/s1	TXYGAIXPPILEQF-WAKWQXKPSA-N	530260	WO2022064009, Compound 37	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.51							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530260&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200203	463793750							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121091	CO[C@@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O2/c1-19-15-21-16-29-28(30-22-9-11-23(35-3)12-10-22)31-26(21)18-33(19)27(34)24-13-14-32(2)17-25(24)20-7-5-4-6-8-20/h4-8,16,19,22-25H,9-15,17-18H2,1-3H3,(H,29,30,31)/t19-,22-,23+,24+,25-/m1/s1	TXYGAIXPPILEQF-UTHIKGHZSA-N	530261	WO2022064009, Compound 38	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 35							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530261&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200203	463793751							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121092	C[C@@H]1Cc2cnc(N[C@H]3CCOC(C)(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O2/c1-19-14-21-16-29-27(30-22-11-13-35-28(2,3)15-22)31-25(21)18-33(19)26(34)23-10-12-32(4)17-24(23)20-8-6-5-7-9-20/h5-9,16,19,22-24H,10-15,17-18H2,1-4H3,(H,29,30,31)/t19-,22+,23+,24-/m1/s1	IFQKMQCWXZVRMZ-QLBRKBSLSA-N	530262	WO2022064009, Compound 39	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<20							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530262&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200204	463793752							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121093	C[C@@H]1Cc2cnc(N[C@H]3CCOC(C)(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O2/c1-19-14-21-16-29-27(30-22-11-13-35-28(2,3)15-22)31-25(21)18-33(19)26(34)23-10-12-32(4)17-24(23)20-8-6-5-7-9-20/h5-9,16,19,22-24H,10-15,17-18H2,1-4H3,(H,29,30,31)/t19-,22+,23+,24-/m1/s1	IFQKMQCWXZVRMZ-QLBRKBSLSA-N	530262	WO2022064009, Compound 39	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5.01							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530262&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200204	463793752							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121094	C[C@@H]1Cc2cnc(N[C@@H]3CCOC(C)(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O2/c1-19-14-21-16-29-27(30-22-11-13-35-28(2,3)15-22)31-25(21)18-33(19)26(34)23-10-12-32(4)17-24(23)20-8-6-5-7-9-20/h5-9,16,19,22-24H,10-15,17-18H2,1-4H3,(H,29,30,31)/t19-,22-,23+,24-/m1/s1	IFQKMQCWXZVRMZ-OUJCMCIWSA-N	530263	WO2022064009, Compound 40	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530263&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200205	463793753							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121095	C[C@@H]1Cc2cnc(N[C@@H]3CCOC(C)(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O2/c1-19-14-21-16-29-27(30-22-11-13-35-28(2,3)15-22)31-25(21)18-33(19)26(34)23-10-12-32(4)17-24(23)20-8-6-5-7-9-20/h5-9,16,19,22-24H,10-15,17-18H2,1-4H3,(H,29,30,31)/t19-,22-,23+,24-/m1/s1	IFQKMQCWXZVRMZ-OUJCMCIWSA-N	530263	WO2022064009, Compound 40	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 7.24							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530263&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200205	463793753							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121096	C[C@@H]1Cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H40N6O3S/c1-20-16-22-17-30-29(31-23-10-14-34(15-11-23)39(37,38)24-8-9-24)32-27(22)19-35(20)28(36)25-12-13-33(2)18-26(25)21-6-4-3-5-7-21/h3-7,17,20,23-26H,8-16,18-19H2,1-2H3,(H,30,31,32)/t20-,25+,26-/m1/s1	WFWDVEDAOQVOAE-RFLWCCGPSA-N	530264	WO2022064009, Compound 41::WO2022064009, Compound 46	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 661							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530264&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200206	463793754							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121097	C[C@@H]1Cc2cnc(NC3CCN(CC3)C3CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H40N6O/c1-20-16-22-17-30-29(31-23-10-14-34(15-11-23)24-8-9-24)32-27(22)19-35(20)28(36)25-12-13-33(2)18-26(25)21-6-4-3-5-7-21/h3-7,17,20,23-26H,8-16,18-19H2,1-2H3,(H,30,31,32)/t20-,25+,26-/m1/s1	OFMSGWUQZVEFMK-RFLWCCGPSA-N	530265	WO2022064009, Compound 42	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 41							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530265&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200207	463793755							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121098	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H33N5O/c1-20-15-23-17-30-28(29-16-21-9-5-3-6-10-21)31-26(23)19-33(20)27(34)24-13-14-32(2)18-25(24)22-11-7-4-8-12-22/h3-12,17,20,24-25H,13-16,18-19H2,1-2H3,(H,29,30,31)/t20-,24+,25-/m1/s1	OHPIHQNDZSUYLV-DCEDVJGZSA-N	530266	WO2022064009, Compound 154::WO2022064009, Compound 43	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530266&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200208	463793756							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121099	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H33N5O/c1-20-15-23-17-30-28(29-16-21-9-5-3-6-10-21)31-26(23)19-33(20)27(34)24-13-14-32(2)18-25(24)22-11-7-4-8-12-22/h3-12,17,20,24-25H,13-16,18-19H2,1-2H3,(H,29,30,31)/t20-,24+,25-/m1/s1	OHPIHQNDZSUYLV-DCEDVJGZSA-N	530266	WO2022064009, Compound 154::WO2022064009, Compound 43	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 7.76							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530266&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200208	463793756							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121100	C[C@@H]1Cc2cnc(NC3CCS(=O)(=O)CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O3S/c1-18-14-20-15-27-26(28-21-9-12-35(33,34)13-10-21)29-24(20)17-31(18)25(32)22-8-11-30(2)16-23(22)19-6-4-3-5-7-19/h3-7,15,18,21-23H,8-14,16-17H2,1-2H3,(H,27,28,29)/t18-,22+,23-/m1/s1	ZLAMRJYPPCFJBU-YFXJRYMSSA-N	530267	WO2022064009, Compound 44	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<20							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530267&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200209	463793757							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121101	C[C@@H]1Cc2cnc(NC3CCS(=O)(=O)CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O3S/c1-18-14-20-15-27-26(28-21-9-12-35(33,34)13-10-21)29-24(20)17-31(18)25(32)22-8-11-30(2)16-23(22)19-6-4-3-5-7-19/h3-7,15,18,21-23H,8-14,16-17H2,1-2H3,(H,27,28,29)/t18-,22+,23-/m1/s1	ZLAMRJYPPCFJBU-YFXJRYMSSA-N	530267	WO2022064009, Compound 44	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.12							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530267&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200209	463793757							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121102	C[C@@H]1Cc2cnc(NC3CCN(CC(F)(F)F)CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H37F3N6O/c1-19-14-21-15-32-27(33-22-8-12-36(13-9-22)18-28(29,30)31)34-25(21)17-37(19)26(38)23-10-11-35(2)16-24(23)20-6-4-3-5-7-20/h3-7,15,19,22-24H,8-14,16-18H2,1-2H3,(H,32,33,34)/t19-,23+,24-/m1/s1	XCCOBJNTGLQIHC-VEXUSMLFSA-N	530268	WO2022064009, Compound 45	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 24							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530268&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200210	463793758							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121103	C[C@@H]1Cc2cnc(NC3CCN(CC(F)(F)F)CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H37F3N6O/c1-19-14-21-15-32-27(33-22-8-12-36(13-9-22)18-28(29,30)31)34-25(21)17-37(19)26(38)23-10-11-35(2)16-24(23)20-6-4-3-5-7-20/h3-7,15,19,22-24H,8-14,16-18H2,1-2H3,(H,32,33,34)/t19-,23+,24-/m1/s1	XCCOBJNTGLQIHC-VEXUSMLFSA-N	530268	WO2022064009, Compound 45	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 22							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530268&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200210	463793758							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121104	C[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O/c1-19-9-11-23(12-10-19)30-28-29-16-22-15-20(2)33(18-26(22)31-28)27(34)24-13-14-32(3)17-25(24)21-7-5-4-6-8-21/h4-8,16,19-20,23-25H,9-15,17-18H2,1-3H3,(H,29,30,31)/t19-,20-,23-,24+,25-/m1/s1	SNKLXUKZGQHXNL-YFUZDLCXSA-N	530269	WO2022064009, Compound 13	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530269&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200211	463793759							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121105	C[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O/c1-19-9-11-23(12-10-19)30-28-29-16-22-15-20(2)33(18-26(22)31-28)27(34)24-13-14-32(3)17-25(24)21-7-5-4-6-8-21/h4-8,16,19-20,23-25H,9-15,17-18H2,1-3H3,(H,29,30,31)/t19-,20-,23-,24+,25-/m1/s1	SNKLXUKZGQHXNL-YFUZDLCXSA-N	530269	WO2022064009, Compound 13	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1.41							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530269&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200211	463793759							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121106	C[C@H]1CC[C@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O/c1-19-9-11-23(12-10-19)30-28-29-16-22-15-20(2)33(18-26(22)31-28)27(34)24-13-14-32(3)17-25(24)21-7-5-4-6-8-21/h4-8,16,19-20,23-25H,9-15,17-18H2,1-3H3,(H,29,30,31)/t19-,20-,23+,24+,25-/m1/s1	SNKLXUKZGQHXNL-BUGIRRBRSA-N	530270	WO2022064009, Compound 14	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 13							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530270&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200211	463793760							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121107	C[C@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccccn1	InChI=1S/C28H34N6O/c1-19-15-22-16-30-28(31-20(2)25-11-7-8-13-29-25)32-26(22)18-34(19)27(35)23-12-14-33(3)17-24(23)21-9-5-4-6-10-21/h4-11,13,16,19-20,23-24H,12,14-15,17-18H2,1-3H3,(H,30,31,32)/t19-,20+,23+,24-/m1/s1	YEPYIWLATCUFMJ-CDPNLFKUSA-N	530271	WO2022064009, Compound 20	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530271	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530271&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200212	463793761							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121108	C[C@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccccn1	InChI=1S/C28H34N6O/c1-19-15-22-16-30-28(31-20(2)25-11-7-8-13-29-25)32-26(22)18-34(19)27(35)23-12-14-33(3)17-24(23)21-9-5-4-6-10-21/h4-11,13,16,19-20,23-24H,12,14-15,17-18H2,1-3H3,(H,30,31,32)/t19-,20+,23+,24-/m1/s1	YEPYIWLATCUFMJ-CDPNLFKUSA-N	530271	WO2022064009, Compound 20	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.46							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530271	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530271&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200212	463793761							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121109	C[C@@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccccn1	InChI=1S/C28H34N6O/c1-19-15-22-16-30-28(31-20(2)25-11-7-8-13-29-25)32-26(22)18-34(19)27(35)23-12-14-33(3)17-24(23)21-9-5-4-6-10-21/h4-11,13,16,19-20,23-24H,12,14-15,17-18H2,1-3H3,(H,30,31,32)/t19-,20-,23+,24-/m1/s1	YEPYIWLATCUFMJ-MYSJAJEPSA-N	530272	WO2022064009, Compound 21	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530272&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200213	463793762							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121110	C[C@@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccccc1	InChI=1S/C29H35N5O/c1-20-16-24-17-30-29(31-21(2)22-10-6-4-7-11-22)32-27(24)19-34(20)28(35)25-14-15-33(3)18-26(25)23-12-8-5-9-13-23/h4-13,17,20-21,25-26H,14-16,18-19H2,1-3H3,(H,30,31,32)/t20-,21-,25+,26-/m1/s1	YYTLAVZZVNYLAF-YTFNCPKPSA-N	530273	WO2022064009, Compound 22	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530273&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200214	463793763							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121111	C[C@@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccccc1	InChI=1S/C29H35N5O/c1-20-16-24-17-30-29(31-21(2)22-10-6-4-7-11-22)32-27(24)19-34(20)28(35)25-14-15-33(3)18-26(25)23-12-8-5-9-13-23/h4-13,17,20-21,25-26H,14-16,18-19H2,1-3H3,(H,30,31,32)/t20-,21-,25+,26-/m1/s1	YYTLAVZZVNYLAF-YTFNCPKPSA-N	530273	WO2022064009, Compound 22	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.46							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530273	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530273&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200214	463793763							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121112	C[C@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccccc1	InChI=1S/C29H35N5O/c1-20-16-24-17-30-29(31-21(2)22-10-6-4-7-11-22)32-27(24)19-34(20)28(35)25-14-15-33(3)18-26(25)23-12-8-5-9-13-23/h4-13,17,20-21,25-26H,14-16,18-19H2,1-3H3,(H,30,31,32)/t20-,21+,25+,26-/m1/s1	YYTLAVZZVNYLAF-YGKRLXNZSA-N	530274	WO2022064009, Compound 23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530274&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200215	463793764							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121113	C[C@@H]1Cc2cnc(NC3CC(C)(C)OC(C)(C)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C30H43N5O2/c1-20-14-22-17-31-28(32-23-15-29(2,3)37-30(4,5)16-23)33-26(22)19-35(20)27(36)24-12-13-34(6)18-25(24)21-10-8-7-9-11-21/h7-11,17,20,23-25H,12-16,18-19H2,1-6H3,(H,31,32,33)/t20-,24+,25-/m1/s1	YUNNNXOAIASJDB-DCEDVJGZSA-N	530275	WO2022064009, Compound 24	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530275&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200216	463793765							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121114	C[C@@H]1Cc2cnc(NC3CCN(CC3)C3COC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H40N6O2/c1-20-14-22-15-30-29(31-23-8-12-34(13-9-23)24-18-37-19-24)32-27(22)17-35(20)28(36)25-10-11-33(2)16-26(25)21-6-4-3-5-7-21/h3-7,15,20,23-26H,8-14,16-19H2,1-2H3,(H,30,31,32)/t20-,25+,26-/m1/s1	AURMEHIOUBZODL-RFLWCCGPSA-N	530276	WO2022064009, Compound 25	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 35							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530276	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530276&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200217	463793766							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121115	C[C@@H]1Cc2cnc(NCC3CCOC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-12-21-14-28-26(27-13-19-9-11-33-17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,14,18-19,22-23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,19?,22+,23-/m1/s1	IPTCAPBTKXTALM-JAAAFKCMSA-N	530277	WO2022064009, Compound 26	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 14							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530277&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200218	463793767							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121116	C[C@@H]1Cc2cnc(NCc3ccc(C)nc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H34N6O/c1-19-9-10-21(14-29-19)15-30-28-31-16-23-13-20(2)34(18-26(23)32-28)27(35)24-11-12-33(3)17-25(24)22-7-5-4-6-8-22/h4-10,14,16,20,24-25H,11-13,15,17-18H2,1-3H3,(H,30,31,32)/t20-,24+,25-/m1/s1	DOSJYEJLKRTFIU-DCEDVJGZSA-N	530278	WO2022064009, Compound 27	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 32							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530278	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530278&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200219	463793768							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121117	C[C@@H]1Cc2cnc(NCC(=O)N3CCCCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H38N6O2/c1-20-15-22-16-29-28(30-17-26(35)33-12-7-4-8-13-33)31-25(22)19-34(20)27(36)23-11-14-32(2)18-24(23)21-9-5-3-6-10-21/h3,5-6,9-10,16,20,23-24H,4,7-8,11-15,17-19H2,1-2H3,(H,29,30,31)/t20-,23+,24-/m1/s1	XLJUAVUMMBEBMZ-FGCOXFRFSA-N	530279	WO2022064009, Compound 28	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 257							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530279&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200220	463793769							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121118	C[C@@H]1Cc2cnc(NC3Cc4ccccc4C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C30H35N5O/c1-20-14-24-17-31-30(32-25-15-22-10-6-7-11-23(22)16-25)33-28(24)19-35(20)29(36)26-12-13-34(2)18-27(26)21-8-4-3-5-9-21/h3-11,17,20,25-27H,12-16,18-19H2,1-2H3,(H,31,32,33)/t20-,26+,27-/m1/s1	OOYQNSZDPNRUJS-JAMKYWPSSA-N	530280	WO2022064009, Compound 29	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530280&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200221	463793770							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121119	C[C@@H]1Cc2cnc(NC3Cc4ccccc4C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C30H35N5O/c1-20-14-24-17-31-30(32-25-15-22-10-6-7-11-23(22)16-25)33-28(24)19-35(20)29(36)26-12-13-34(2)18-27(26)21-8-4-3-5-9-21/h3-11,17,20,25-27H,12-16,18-19H2,1-2H3,(H,31,32,33)/t20-,26+,27-/m1/s1	OOYQNSZDPNRUJS-JAMKYWPSSA-N	530280	WO2022064009, Compound 29	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.82							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530280&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200221	463793770							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121120	CC(C)n1cc(CNc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)cn1	InChI=1S/C28H37N7O/c1-19(2)35-16-21(14-31-35)13-29-28-30-15-23-12-20(3)34(18-26(23)32-28)27(36)24-10-11-33(4)17-25(24)22-8-6-5-7-9-22/h5-9,14-16,19-20,24-25H,10-13,17-18H2,1-4H3,(H,29,30,32)/t20-,24+,25-/m1/s1	VGOIJQNFWVNQAW-DCEDVJGZSA-N	530281	WO2022064009, Compound 30	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 93							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530281&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200222	463793771							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121121	C[C@@H]1Cc2cnc(NC3CCN(CC3)C(=O)CC3CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C31H42N6O2/c1-21-16-24-18-32-31(33-25-10-14-36(15-11-25)29(38)17-22-8-9-22)34-28(24)20-37(21)30(39)26-12-13-35(2)19-27(26)23-6-4-3-5-7-23/h3-7,18,21-22,25-27H,8-17,19-20H2,1-2H3,(H,32,33,34)/t21-,26+,27-/m1/s1	GPKJURVHIMHBBY-COFKYPDJSA-N	530282	WO2022064009, Compound 31	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 15							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530282&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200223	463793772							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121122	C[C@@H]1Cc2cnc(NCc3c(F)cccc3F)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H31F2N5O/c1-18-13-20-14-31-28(32-15-22-24(29)9-6-10-25(22)30)33-26(20)17-35(18)27(36)21-11-12-34(2)16-23(21)19-7-4-3-5-8-19/h3-10,14,18,21,23H,11-13,15-17H2,1-2H3,(H,31,32,33)/t18-,21+,23-/m1/s1	FCALXDFJLVUWIQ-RZFNWQHOSA-N	530283	WO2022064009, Compound 32	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 13							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530283&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200224	463793773							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121123	C[C@@H]1Cc2cnc(NC3CCN(CC3)C(=O)C3CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C30H40N6O2/c1-20-16-23-17-31-30(32-24-10-14-35(15-11-24)28(37)22-8-9-22)33-27(23)19-36(20)29(38)25-12-13-34(2)18-26(25)21-6-4-3-5-7-21/h3-7,17,20,22,24-26H,8-16,18-19H2,1-2H3,(H,31,32,33)/t20-,25+,26-/m1/s1	UCWPUDFVYCANSL-RFLWCCGPSA-N	530284	WO2022064009, Compound 33	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 13							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530284&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200225	463793774							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121124	C[C@@H]1Cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H40N6O3S/c1-20-16-22-17-30-29(31-23-10-14-34(15-11-23)39(37,38)24-8-9-24)32-27(22)19-35(20)28(36)25-12-13-33(2)18-26(25)21-6-4-3-5-7-21/h3-7,17,20,23-26H,8-16,18-19H2,1-2H3,(H,30,31,32)/t20-,25+,26-/m1/s1	WFWDVEDAOQVOAE-RFLWCCGPSA-N	530264	WO2022064009, Compound 41::WO2022064009, Compound 46	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 661							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530264&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200206	463793754							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121125	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-14-20-15-27-26(28-21-9-12-33-13-10-21)29-24(20)17-31(18)25(32)22-8-11-30(2)16-23(22)19-6-4-3-5-7-19/h3-7,15,18,21-23H,8-14,16-17H2,1-2H3,(H,27,28,29)/t18-,22+,23-/m1/s1	XWPPDZKREULSMT-YFXJRYMSSA-N	530286	WO2022064009, Compound 156::WO2022064009, Compound 47	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<20							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530286&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200226	463793775							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121126	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-14-20-15-27-26(28-21-9-12-33-13-10-21)29-24(20)17-31(18)25(32)22-8-11-30(2)16-23(22)19-6-4-3-5-7-19/h3-7,15,18,21-23H,8-14,16-17H2,1-2H3,(H,27,28,29)/t18-,22+,23-/m1/s1	XWPPDZKREULSMT-YFXJRYMSSA-N	530286	WO2022064009, Compound 156::WO2022064009, Compound 47	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5.01							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530286&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200226	463793775							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121127	C[C@@H]1Cc2cnc(NCc3ccsc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H31N5OS/c1-18-12-21-14-28-26(27-13-19-9-11-33-17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,9,11,14,17-18,22-23H,8,10,12-13,15-16H2,1-2H3,(H,27,28,29)/t18-,22+,23-/m1/s1	KKMLJXPEBGIWMT-YFXJRYMSSA-N	530287	WO2022064009, Compound 48	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 26							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530287&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200227	463793776							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121128	C[C@@H]1Cc2cnc(NCc3ccsc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H31N5OS/c1-18-12-21-14-28-26(27-13-19-9-11-33-17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,9,11,14,17-18,22-23H,8,10,12-13,15-16H2,1-2H3,(H,27,28,29)/t18-,22+,23-/m1/s1	KKMLJXPEBGIWMT-YFXJRYMSSA-N	530287	WO2022064009, Compound 48	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 12							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530287&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200227	463793776							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121129	C[C@@H]1Cc2cnc(NCC3CCS(=O)(=O)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O3S/c1-18-12-21-14-28-26(27-13-19-9-11-35(33,34)17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,14,18-19,22-23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,19?,22+,23-/m1/s1	REDWPMAMKVIGTL-JAAAFKCMSA-N	530288	WO2022064009, Compound 49	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 240							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530288&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200228	463793777							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121130	C[C@@H]1Cc2cnc(NCC3CCS(=O)(=O)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O3S/c1-18-12-21-14-28-26(27-13-19-9-11-35(33,34)17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,14,18-19,22-23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,19?,22+,23-/m1/s1	REDWPMAMKVIGTL-JAAAFKCMSA-N	530288	WO2022064009, Compound 49	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 63							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530288&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200228	463793777							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121131	C[C@@H]1Cc2cnc(NCc3ccc(C)o3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H33N5O2/c1-18-13-21-14-28-27(29-15-22-10-9-19(2)34-22)30-25(21)17-32(18)26(33)23-11-12-31(3)16-24(23)20-7-5-4-6-8-20/h4-10,14,18,23-24H,11-13,15-17H2,1-3H3,(H,28,29,30)/t18-,23+,24-/m1/s1	ZUILKKNRCJJKQL-PUZWTLIVSA-N	530289	WO2022064009, Compound 50	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 25							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530289&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200229	463793778							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121132	C[C@@H]1Cc2cnc(NCc3ccc(C)o3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H33N5O2/c1-18-13-21-14-28-27(29-15-22-10-9-19(2)34-22)30-25(21)17-32(18)26(33)23-11-12-31(3)16-24(23)20-7-5-4-6-8-20/h4-10,14,18,23-24H,11-13,15-17H2,1-3H3,(H,28,29,30)/t18-,23+,24-/m1/s1	ZUILKKNRCJJKQL-PUZWTLIVSA-N	530289	WO2022064009, Compound 50	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8.91							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530289&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200229	463793778							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121133	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H33N7O/c1-18-13-20-14-27-26(28-15-21-9-12-32(3)30-21)29-24(20)17-33(18)25(34)22-10-11-31(2)16-23(22)19-7-5-4-6-8-19/h4-9,12,14,18,22-23H,10-11,13,15-17H2,1-3H3,(H,27,28,29)/t18-,22+,23-/m1/s1	KLUZOYLPHBNTLS-YFXJRYMSSA-N	530245	WO2022064009, Compound 1::WO2022064009, Compound 51	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 51							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530245&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200189	463793736							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121134	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H33N7O/c1-18-13-20-14-27-26(28-15-21-9-12-32(3)30-21)29-24(20)17-33(18)25(34)22-10-11-31(2)16-23(22)19-7-5-4-6-8-19/h4-9,12,14,18,22-23H,10-11,13,15-17H2,1-3H3,(H,27,28,29)/t18-,22+,23-/m1/s1	KLUZOYLPHBNTLS-YFXJRYMSSA-N	530245	WO2022064009, Compound 1::WO2022064009, Compound 51	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8.32							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530245&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200189	463793736							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121135	C[C@@H]1Cc2cnc(NCc3cnc(C)[nH]3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1			530291	WO2022064009, Compound 52	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530291&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200230	463793779							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121136	C[C@@H]1Cc2cnc(NCc3cnc(C)[nH]3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1			530291	WO2022064009, Compound 52	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 13							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530291&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200230	463793779							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121137	C[C@@H]1Cc2cnc(NC[C@H]3CCOC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-12-21-14-28-26(27-13-19-9-11-33-17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,14,18-19,22-23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,19-,22+,23-/m1/s1	IPTCAPBTKXTALM-PJIZGREPSA-N	530292	WO2022064009, Compound 53::WO2022064009, Compound 68	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 41							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530292&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200231	463793780							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121138	C[C@@H]1Cc2cnc(NC[C@H]3CCOC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-12-21-14-28-26(27-13-19-9-11-33-17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,14,18-19,22-23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,19-,22+,23-/m1/s1	IPTCAPBTKXTALM-PJIZGREPSA-N	530292	WO2022064009, Compound 53::WO2022064009, Compound 68	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 10							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530292&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200231	463793780							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121139	C[C@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccn(C)n1	InChI=1S/C27H35N7O/c1-18-14-21-15-28-27(29-19(2)24-11-13-33(4)31-24)30-25(21)17-34(18)26(35)22-10-12-32(3)16-23(22)20-8-6-5-7-9-20/h5-9,11,13,15,18-19,22-23H,10,12,14,16-17H2,1-4H3,(H,28,29,30)/t18-,19+,22+,23-/m1/s1	XZOCZBGQAZLANR-CQIJRDABSA-N	530293	WO2022064009, Compound 54	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 12							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530293&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200232	463793781							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121140	C[C@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccn(C)n1	InChI=1S/C27H35N7O/c1-18-14-21-15-28-27(29-19(2)24-11-13-33(4)31-24)30-25(21)17-34(18)26(35)22-10-12-32(3)16-23(22)20-8-6-5-7-9-20/h5-9,11,13,15,18-19,22-23H,10,12,14,16-17H2,1-4H3,(H,28,29,30)/t18-,19+,22+,23-/m1/s1	XZOCZBGQAZLANR-CQIJRDABSA-N	530293	WO2022064009, Compound 54	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5.13							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530293&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200232	463793781							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121141	C[C@@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccn(C)n1	InChI=1S/C27H35N7O/c1-18-14-21-15-28-27(29-19(2)24-11-13-33(4)31-24)30-25(21)17-34(18)26(35)22-10-12-32(3)16-23(22)20-8-6-5-7-9-20/h5-9,11,13,15,18-19,22-23H,10,12,14,16-17H2,1-4H3,(H,28,29,30)/t18-,19-,22+,23-/m1/s1	XZOCZBGQAZLANR-PJIZGREPSA-N	530294	WO2022064009, Compound 55	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 141							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530294&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200233	463793782							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121142	C[C@@H](Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1)c1ccn(C)n1	InChI=1S/C27H35N7O/c1-18-14-21-15-28-27(29-19(2)24-11-13-33(4)31-24)30-25(21)17-34(18)26(35)22-10-12-32(3)16-23(22)20-8-6-5-7-9-20/h5-9,11,13,15,18-19,22-23H,10,12,14,16-17H2,1-4H3,(H,28,29,30)/t18-,19-,22+,23-/m1/s1	XZOCZBGQAZLANR-PJIZGREPSA-N	530294	WO2022064009, Compound 55	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 39							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530294&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200233	463793782							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121143	C[C@@H]1Cc2cnc(NCc3cc(C(F)F)n(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H33F2N7O/c1-17-11-19-13-30-27(31-14-20-12-24(25(28)29)35(3)33-20)32-23(19)16-36(17)26(37)21-9-10-34(2)15-22(21)18-7-5-4-6-8-18/h4-8,12-13,17,21-22,25H,9-11,14-16H2,1-3H3,(H,30,31,32)/t17-,21+,22-/m1/s1	LWHZTVMIVDWSGG-VOQZNFBZSA-N	530295	WO2022064009, Compound 56	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 141							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530295&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200234	463793783							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121144	C[C@@H]1Cc2cnc(NCc3cc(C(F)F)n(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H33F2N7O/c1-17-11-19-13-30-27(31-14-20-12-24(25(28)29)35(3)33-20)32-23(19)16-36(17)26(37)21-9-10-34(2)15-22(21)18-7-5-4-6-8-18/h4-8,12-13,17,21-22,25H,9-11,14-16H2,1-3H3,(H,30,31,32)/t17-,21+,22-/m1/s1	LWHZTVMIVDWSGG-VOQZNFBZSA-N	530295	WO2022064009, Compound 56	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 36							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530295&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200234	463793783							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121145	C[C@@H]1Cc2cnc(NCc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H33N7O/c1-18-11-21-14-28-26(27-12-19-13-29-32(3)15-19)30-24(21)17-33(18)25(34)22-9-10-31(2)16-23(22)20-7-5-4-6-8-20/h4-8,13-15,18,22-23H,9-12,16-17H2,1-3H3,(H,27,28,30)/t18-,22+,23-/m1/s1	ZNZJVHNCJHWVGU-YFXJRYMSSA-N	530296	WO2022064009, Compound 57	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 219							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530296	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530296&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200235	463793784							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121146	C[C@@H]1Cc2cnc(NCc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H33N7O/c1-18-11-21-14-28-26(27-12-19-13-29-32(3)15-19)30-24(21)17-33(18)25(34)22-9-10-31(2)16-23(22)20-7-5-4-6-8-20/h4-8,13-15,18,22-23H,9-12,16-17H2,1-3H3,(H,27,28,30)/t18-,22+,23-/m1/s1	ZNZJVHNCJHWVGU-YFXJRYMSSA-N	530296	WO2022064009, Compound 57	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 30							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530296	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530296&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200235	463793784							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121147	CCn1ccc(CNc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)n1	InChI=1S/C27H35N7O/c1-4-33-13-10-22(31-33)16-29-27-28-15-21-14-19(2)34(18-25(21)30-27)26(35)23-11-12-32(3)17-24(23)20-8-6-5-7-9-20/h5-10,13,15,19,23-24H,4,11-12,14,16-18H2,1-3H3,(H,28,29,30)/t19-,23+,24-/m1/s1	JMCJVWDRPZXEJP-VEXUSMLFSA-N	530297	WO2022064009, Compound 58	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530297	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530297&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200236	463793785							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121148	CCn1ccc(CNc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)n1	InChI=1S/C27H35N7O/c1-4-33-13-10-22(31-33)16-29-27-28-15-21-14-19(2)34(18-25(21)30-27)26(35)23-11-12-32(3)17-24(23)20-8-6-5-7-9-20/h5-10,13,15,19,23-24H,4,11-12,14,16-18H2,1-3H3,(H,28,29,30)/t19-,23+,24-/m1/s1	JMCJVWDRPZXEJP-VEXUSMLFSA-N	530297	WO2022064009, Compound 58	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.34							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530297	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530297&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200236	463793785							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121149	C[C@@H]1Cc2cnc(N[C@H]3CCC[C@H](O)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-13-20-15-28-27(29-21-9-6-10-22(33)14-21)30-25(20)17-32(18)26(34)23-11-12-31(2)16-24(23)19-7-4-3-5-8-19/h3-5,7-8,15,18,21-24,33H,6,9-14,16-17H2,1-2H3,(H,28,29,30)/t18-,21+,22+,23+,24-/m1/s1	IRYRLBLRMDIRSC-ANQOARCNSA-N	530298	WO2022064009, Compound 59	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530298&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200237	463793786							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121150	C[C@@H]1Cc2cnc(N[C@H]3CCC[C@H](O)C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-13-20-15-28-27(29-21-9-6-10-22(33)14-21)30-25(20)17-32(18)26(34)23-11-12-31(2)16-24(23)19-7-4-3-5-8-19/h3-5,7-8,15,18,21-24,33H,6,9-14,16-17H2,1-2H3,(H,28,29,30)/t18-,21+,22+,23+,24-/m1/s1	IRYRLBLRMDIRSC-ANQOARCNSA-N	530298	WO2022064009, Compound 59	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5.25							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530298&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200237	463793786							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121151	C[C@@H]1Cc2cnc(NCC3CN(C)C=C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H36N6O/c1-19-13-22-15-29-27(28-14-20-9-11-31(2)16-20)30-25(22)18-33(19)26(34)23-10-12-32(3)17-24(23)21-7-5-4-6-8-21/h4-9,11,15,19-20,23-24H,10,12-14,16-18H2,1-3H3,(H,28,29,30)/t19-,20?,23+,24-/m1/s1	OTKSTNNKSYASFT-OQVRYUHUSA-N	530299	WO2022064009, Compound 60	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530299&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200238	463793787							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121152	C[C@@H]1Cc2cnc(NCC3CN(C)C=C3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H36N6O/c1-19-13-22-15-29-27(28-14-20-9-11-31(2)16-20)30-25(22)18-33(19)26(34)23-10-12-32(3)17-24(23)21-7-5-4-6-8-21/h4-9,11,15,19-20,23-24H,10,12-14,16-18H2,1-3H3,(H,28,29,30)/t19-,20?,23+,24-/m1/s1	OTKSTNNKSYASFT-OQVRYUHUSA-N	530299	WO2022064009, Compound 60	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.55							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530299&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200238	463793787							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121153	C[C@@H]1Cc2cnc(NCc3nn(C)cc3C)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H35N7O/c1-18-15-33(4)31-24(18)14-29-27-28-13-21-12-19(2)34(17-25(21)30-27)26(35)22-10-11-32(3)16-23(22)20-8-6-5-7-9-20/h5-9,13,15,19,22-23H,10-12,14,16-17H2,1-4H3,(H,28,29,30)/t19-,22+,23-/m1/s1	ZEFMRBGHPIRHMS-WTIAFYNJSA-N	530300	WO2022064009, Compound 61	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530300&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200239	463793788							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121154	C[C@@H]1Cc2cnc(NCc3nn(C)cc3C)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H35N7O/c1-18-15-33(4)31-24(18)14-29-27-28-13-21-12-19(2)34(17-25(21)30-27)26(35)22-10-11-32(3)16-23(22)20-8-6-5-7-9-20/h5-9,13,15,19,22-23H,10-12,14,16-17H2,1-4H3,(H,28,29,30)/t19-,22+,23-/m1/s1	ZEFMRBGHPIRHMS-WTIAFYNJSA-N	530300	WO2022064009, Compound 61	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530300&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200239	463793788							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121155	C[C@@H]1Cc2cnc(NC[C@@H]3CCOC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-12-21-14-28-26(27-13-19-9-11-33-17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,14,18-19,22-23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,19+,22+,23-/m1/s1	IPTCAPBTKXTALM-CQIJRDABSA-N	530301	WO2022064009, Compound 62::WO2022064009, Compound 67	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530301&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200240	463793789							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121156	C[C@@H]1Cc2cnc(NC[C@@H]3CCOC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-12-21-14-28-26(27-13-19-9-11-33-17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,14,18-19,22-23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,19+,22+,23-/m1/s1	IPTCAPBTKXTALM-CQIJRDABSA-N	530301	WO2022064009, Compound 62::WO2022064009, Compound 67	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 4.68							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530301&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200240	463793789							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121157	C[C@@H]1Cc2cnc(NCc3cn(C)cn3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H33N7O/c1-18-11-20-12-27-26(28-13-21-14-32(3)17-29-21)30-24(20)16-33(18)25(34)22-9-10-31(2)15-23(22)19-7-5-4-6-8-19/h4-8,12,14,17-18,22-23H,9-11,13,15-16H2,1-3H3,(H,27,28,30)/t18-,22+,23-/m1/s1	ZPFUMWQJICWMME-YFXJRYMSSA-N	530302	WO2022064009, Compound 63	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 42							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530302&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200241	463793790							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121158	C[C@@H]1Cc2cnc(NC3CCC(F)(F)CC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H35F2N5O/c1-18-14-20-15-30-26(31-21-8-11-27(28,29)12-9-21)32-24(20)17-34(18)25(35)22-10-13-33(2)16-23(22)19-6-4-3-5-7-19/h3-7,15,18,21-23H,8-14,16-17H2,1-2H3,(H,30,31,32)/t18-,22+,23-/m1/s1	HQVAFGRLEQOTJJ-YFXJRYMSSA-N	530303	WO2022064009, Compound 64	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530303&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200242	463793791							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121159	C[C@@H]1Cc2cnc(NCc3cc(C)n(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H35N7O/c1-18-13-22(31-33(18)4)15-29-27-28-14-21-12-19(2)34(17-25(21)30-27)26(35)23-10-11-32(3)16-24(23)20-8-6-5-7-9-20/h5-9,13-14,19,23-24H,10-12,15-17H2,1-4H3,(H,28,29,30)/t19-,23+,24-/m1/s1	OYWBASDPEMJOQW-VEXUSMLFSA-N	530304	WO2022064009, Compound 65	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 26							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530304&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200243	463793792							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121160	C[C@@H]1Cc2cnc(NCc3cc(C)n(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H35N7O/c1-18-13-22(31-33(18)4)15-29-27-28-14-21-12-19(2)34(17-25(21)30-27)26(35)23-10-11-32(3)16-24(23)20-8-6-5-7-9-20/h5-9,13-14,19,23-24H,10-12,15-17H2,1-4H3,(H,28,29,30)/t19-,23+,24-/m1/s1	OYWBASDPEMJOQW-VEXUSMLFSA-N	530304	WO2022064009, Compound 65	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 47							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530304&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200243	463793792							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121161	CC(C)n1ccc(CNc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)n1	InChI=1S/C28H37N7O/c1-19(2)35-13-10-23(32-35)16-30-28-29-15-22-14-20(3)34(18-26(22)31-28)27(36)24-11-12-33(4)17-25(24)21-8-6-5-7-9-21/h5-10,13,15,19-20,24-25H,11-12,14,16-18H2,1-4H3,(H,29,30,31)/t20-,24+,25-/m1/s1	GPXWBENFZHMPSA-DCEDVJGZSA-N	530305	WO2022064009, Compound 66	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530305&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200244	463793793							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121162	CC(C)n1ccc(CNc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)n1	InChI=1S/C28H37N7O/c1-19(2)35-13-10-23(32-35)16-30-28-29-15-22-14-20(3)34(18-26(22)31-28)27(36)24-11-12-33(4)17-25(24)21-8-6-5-7-9-21/h5-10,13,15,19-20,24-25H,11-12,14,16-18H2,1-4H3,(H,29,30,31)/t20-,24+,25-/m1/s1	GPXWBENFZHMPSA-DCEDVJGZSA-N	530305	WO2022064009, Compound 66	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.75							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530305&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200244	463793793							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121163	C[C@@H]1Cc2cnc(NC[C@@H]3CCOC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-12-21-14-28-26(27-13-19-9-11-33-17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,14,18-19,22-23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,19+,22+,23-/m1/s1	IPTCAPBTKXTALM-CQIJRDABSA-N	530301	WO2022064009, Compound 62::WO2022064009, Compound 67	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530301&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200240	463793789							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121164	C[C@@H]1Cc2cnc(NC[C@@H]3CCOC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-12-21-14-28-26(27-13-19-9-11-33-17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,14,18-19,22-23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,19+,22+,23-/m1/s1	IPTCAPBTKXTALM-CQIJRDABSA-N	530301	WO2022064009, Compound 62::WO2022064009, Compound 67	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 17							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530301&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200240	463793789							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121165	C[C@@H]1Cc2cnc(NC[C@H]3CCOC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-12-21-14-28-26(27-13-19-9-11-33-17-19)29-24(21)16-31(18)25(32)22-8-10-30(2)15-23(22)20-6-4-3-5-7-20/h3-7,14,18-19,22-23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,19-,22+,23-/m1/s1	IPTCAPBTKXTALM-PJIZGREPSA-N	530292	WO2022064009, Compound 53::WO2022064009, Compound 68	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 14							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530292&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200231	463793780							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121166	C[C@@H]1Cc2cnc(N[C@H]3CC[C@@H](CC3)OC(F)F)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H37F2N5O2/c1-18-14-20-15-31-28(32-21-8-10-22(11-9-21)37-27(29)30)33-25(20)17-35(18)26(36)23-12-13-34(2)16-24(23)19-6-4-3-5-7-19/h3-7,15,18,21-24,27H,8-14,16-17H2,1-2H3,(H,31,32,33)/t18-,21-,22-,23+,24-/m1/s1	DURIQOPETKUDHV-XNZCMHNBSA-N	530308	WO2022064009, Compound 69	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530308&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200245	463793794							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121167	C[C@@H]1Cc2cnc(N[C@H]3CC[C@@H](CC3)OC(F)F)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H37F2N5O2/c1-18-14-20-15-31-28(32-21-8-10-22(11-9-21)37-27(29)30)33-25(20)17-35(18)26(36)23-12-13-34(2)16-24(23)19-6-4-3-5-7-19/h3-7,15,18,21-24,27H,8-14,16-17H2,1-2H3,(H,31,32,33)/t18-,21-,22-,23+,24-/m1/s1	DURIQOPETKUDHV-XNZCMHNBSA-N	530308	WO2022064009, Compound 69	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.69							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530308&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200245	463793794							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121168	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H33N5O/c1-20-15-23-17-30-28(29-16-21-9-5-3-6-10-21)31-26(23)19-33(20)27(34)24-13-14-32(2)18-25(24)22-11-7-4-8-12-22/h3-12,17,20,24-25H,13-16,18-19H2,1-2H3,(H,29,30,31)/t20-,24+,25-/m1/s1	OHPIHQNDZSUYLV-DCEDVJGZSA-N	530309	WO2022064009, Compound 70	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530309&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200208	463793795							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121169	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H33N5O/c1-20-15-23-17-30-28(29-16-21-9-5-3-6-10-21)31-26(23)19-33(20)27(34)24-13-14-32(2)18-25(24)22-11-7-4-8-12-22/h3-12,17,20,24-25H,13-16,18-19H2,1-2H3,(H,29,30,31)/t20-,24+,25-/m1/s1	OHPIHQNDZSUYLV-DCEDVJGZSA-N	530309	WO2022064009, Compound 70	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1.78							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530309&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200208	463793795							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121170	C[C@@H]1Cc2cnc(N[C@@H](CO)c3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H35N5O2/c1-20-15-23-16-30-29(32-27(19-35)22-11-7-4-8-12-22)31-26(23)18-34(20)28(36)24-13-14-33(2)17-25(24)21-9-5-3-6-10-21/h3-12,16,20,24-25,27,35H,13-15,17-19H2,1-2H3,(H,30,31,32)/t20-,24+,25-,27+/m1/s1	FODIZQZDGQYPMD-TVZVLCPFSA-N	530310	WO2022064009, Compound 71	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530310&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200246	463793796							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121171	C[C@@H]1Cc2cnc(N[C@@H](CO)c3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H35N5O2/c1-20-15-23-16-30-29(32-27(19-35)22-11-7-4-8-12-22)31-26(23)18-34(20)28(36)24-13-14-33(2)17-25(24)21-9-5-3-6-10-21/h3-12,16,20,24-25,27,35H,13-15,17-19H2,1-2H3,(H,30,31,32)/t20-,24+,25-,27+/m1/s1	FODIZQZDGQYPMD-TVZVLCPFSA-N	530310	WO2022064009, Compound 71	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.88							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530310&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200246	463793796							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121172	C[C@@H]1Cc2cnc(N[C@H](CO)c3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H35N5O2/c1-20-15-23-16-30-29(32-27(19-35)22-11-7-4-8-12-22)31-26(23)18-34(20)28(36)24-13-14-33(2)17-25(24)21-9-5-3-6-10-21/h3-12,16,20,24-25,27,35H,13-15,17-19H2,1-2H3,(H,30,31,32)/t20-,24+,25-,27-/m1/s1	FODIZQZDGQYPMD-GAIMPSMFSA-N	530311	WO2022064009, Compound 72	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530311&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200247	463793797							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121173	C[C@@H]1Cc2cnc(N[C@H](CO)c3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H35N5O2/c1-20-15-23-16-30-29(32-27(19-35)22-11-7-4-8-12-22)31-26(23)18-34(20)28(36)24-13-14-33(2)17-25(24)21-9-5-3-6-10-21/h3-12,16,20,24-25,27,35H,13-15,17-19H2,1-2H3,(H,30,31,32)/t20-,24+,25-,27-/m1/s1	FODIZQZDGQYPMD-GAIMPSMFSA-N	530311	WO2022064009, Compound 72	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.03							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530311&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200247	463793797							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121174	CC(C1CC1)n1cc(Nc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)cn1	InChI=1S/C29H37N7O/c1-19-13-23-14-30-29(32-24-15-31-36(16-24)20(2)21-9-10-21)33-27(23)18-35(19)28(37)25-11-12-34(3)17-26(25)22-7-5-4-6-8-22/h4-8,14-16,19-21,25-26H,9-13,17-18H2,1-3H3,(H,30,32,33)/t19-,20?,25+,26-/m1/s1	NEWAZBOVOUASCX-QQSFODMOSA-N	530312	WO2022064009, Compound 73	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 36							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530312&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200248	463793798							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121175	CC(C1CC1)n1cc(Nc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)cn1	InChI=1S/C29H37N7O/c1-19-13-23-14-30-29(32-24-15-31-36(16-24)20(2)21-9-10-21)33-27(23)18-35(19)28(37)25-11-12-34(3)17-26(25)22-7-5-4-6-8-22/h4-8,14-16,19-21,25-26H,9-13,17-18H2,1-3H3,(H,30,32,33)/t19-,20?,25+,26-/m1/s1	NEWAZBOVOUASCX-QQSFODMOSA-N	530312	WO2022064009, Compound 73	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5.75							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530312&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200248	463793798							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121176	C[C@@H]1Cc2cnc(Nc3cnn(CC(C)(C)O)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H37N7O2/c1-19-12-21-13-29-27(31-22-14-30-34(15-22)18-28(2,3)37)32-25(21)17-35(19)26(36)23-10-11-33(4)16-24(23)20-8-6-5-7-9-20/h5-9,13-15,19,23-24,37H,10-12,16-18H2,1-4H3,(H,29,31,32)/t19-,23+,24-/m1/s1	ARXWXXQZCCPULL-VEXUSMLFSA-N	530313	WO2022064009, Compound 74	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 19							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530313&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200249	463793799							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121177	C[C@@H]1Cc2cnc(Nc3cnn(CC(C)(C)O)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H37N7O2/c1-19-12-21-13-29-27(31-22-14-30-34(15-22)18-28(2,3)37)32-25(21)17-35(19)26(36)23-10-11-33(4)16-24(23)20-8-6-5-7-9-20/h5-9,13-15,19,23-24,37H,10-12,16-18H2,1-4H3,(H,29,31,32)/t19-,23+,24-/m1/s1	ARXWXXQZCCPULL-VEXUSMLFSA-N	530313	WO2022064009, Compound 74	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 10.00							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530313&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200249	463793799							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121178	C[C@@H]1Cc2cnc(Nc3ccnc(c3)C(F)F)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H30F2N6O/c1-17-12-19-14-31-27(32-20-8-10-30-23(13-20)25(28)29)33-24(19)16-35(17)26(36)21-9-11-34(2)15-22(21)18-6-4-3-5-7-18/h3-8,10,13-14,17,21-22,25H,9,11-12,15-16H2,1-2H3,(H,30,31,32,33)/t17-,21+,22-/m1/s1	VKJVBPAULLWBBX-VOQZNFBZSA-N	530314	WO2022064009, Compound 75	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 35							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530314	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530314&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200250	463793800							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121179	C[C@@H]1Cc2cnc(Nc3ccnc(c3)C(F)F)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H30F2N6O/c1-17-12-19-14-31-27(32-20-8-10-30-23(13-20)25(28)29)33-24(19)16-35(17)26(36)21-9-11-34(2)15-22(21)18-6-4-3-5-7-18/h3-8,10,13-14,17,21-22,25H,9,11-12,15-16H2,1-2H3,(H,30,31,32,33)/t17-,21+,22-/m1/s1	VKJVBPAULLWBBX-VOQZNFBZSA-N	530314	WO2022064009, Compound 75	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.12							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530314	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530314&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200250	463793800							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121180	C[C@@H]1Cc2cnc(Nc3cnn4CCCCc34)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H35N7O/c1-19-14-21-15-29-28(31-24-16-30-35-12-7-6-10-26(24)35)32-25(21)18-34(19)27(36)22-11-13-33(2)17-23(22)20-8-4-3-5-9-20/h3-5,8-9,15-16,19,22-23H,6-7,10-14,17-18H2,1-2H3,(H,29,31,32)/t19-,22+,23-/m1/s1	BVDRDDYESBVSLO-WTIAFYNJSA-N	530315	WO2022064009, Compound 77	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 30							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530315	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530315&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200251	463793801							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121181	C[C@@H]1Cc2cnc(Nc3cnn4CCCCc34)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H35N7O/c1-19-14-21-15-29-28(31-24-16-30-35-12-7-6-10-26(24)35)32-25(21)18-34(19)27(36)22-11-13-33(2)17-23(22)20-8-4-3-5-9-20/h3-5,8-9,15-16,19,22-23H,6-7,10-14,17-18H2,1-2H3,(H,29,31,32)/t19-,22+,23-/m1/s1	BVDRDDYESBVSLO-WTIAFYNJSA-N	530315	WO2022064009, Compound 77	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 13							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530315	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530315&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200251	463793801							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121182	C[C@@H]1Cc2cnc(Nc3ccnc(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H32N6O/c1-18-13-22(9-11-28-18)30-27-29-15-21-14-19(2)33(17-25(21)31-27)26(34)23-10-12-32(3)16-24(23)20-7-5-4-6-8-20/h4-9,11,13,15,19,23-24H,10,12,14,16-17H2,1-3H3,(H,28,29,30,31)/t19-,23+,24-/m1/s1	BYUBAOZAEVKQHP-VEXUSMLFSA-N	530316	WO2022064009, Compound 78	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 12							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530316&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200252	463793802							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121183	C[C@@H]1Cc2cnc(Nc3ccnc(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H32N6O/c1-18-13-22(9-11-28-18)30-27-29-15-21-14-19(2)33(17-25(21)31-27)26(34)23-10-12-32(3)16-24(23)20-7-5-4-6-8-20/h4-9,11,13,15,19,23-24H,10,12,14,16-17H2,1-3H3,(H,28,29,30,31)/t19-,23+,24-/m1/s1	BYUBAOZAEVKQHP-VEXUSMLFSA-N	530316	WO2022064009, Compound 78	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 4.27							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530316&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200252	463793802							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121184	C[C@@H]1Cc2cnc(Nc3ccnn3C)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H31N7O/c1-17-13-19-14-26-25(29-23-9-11-27-31(23)3)28-22(19)16-32(17)24(33)20-10-12-30(2)15-21(20)18-7-5-4-6-8-18/h4-9,11,14,17,20-21H,10,12-13,15-16H2,1-3H3,(H,26,28,29)/t17-,20+,21-/m1/s1	BNFRINCMGZLWGX-JRGCBEDISA-N	530317	WO2022064009, Compound 79	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 43							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530317	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530317&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200253	463793803							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121185	C[C@@H]1Cc2cnc(Nc3ccnn3C)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H31N7O/c1-17-13-19-14-26-25(29-23-9-11-27-31(23)3)28-22(19)16-32(17)24(33)20-10-12-30(2)15-21(20)18-7-5-4-6-8-18/h4-9,11,14,17,20-21H,10,12-13,15-16H2,1-3H3,(H,26,28,29)/t17-,20+,21-/m1/s1	BNFRINCMGZLWGX-JRGCBEDISA-N	530317	WO2022064009, Compound 79	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 17							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530317	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530317&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200253	463793803							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121186	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H31N7O/c1-17-11-19-12-26-25(28-20-13-27-31(3)14-20)29-23(19)16-32(17)24(33)21-9-10-30(2)15-22(21)18-7-5-4-6-8-18/h4-8,12-14,17,21-22H,9-11,15-16H2,1-3H3,(H,26,28,29)/t17-,21+,22-/m1/s1	ULPUTPYMWGDKDQ-VOQZNFBZSA-N	530318	WO2022064009, Compound 82::WO2022064009, Compound 91	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530318	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530318&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200254	463793804							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121187	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H31N7O/c1-17-11-19-12-26-25(28-20-13-27-31(3)14-20)29-23(19)16-32(17)24(33)21-9-10-30(2)15-22(21)18-7-5-4-6-8-18/h4-8,12-14,17,21-22H,9-11,15-16H2,1-3H3,(H,26,28,29)/t17-,21+,22-/m1/s1	ULPUTPYMWGDKDQ-VOQZNFBZSA-N	530318	WO2022064009, Compound 82::WO2022064009, Compound 91	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.14							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530318	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530318&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200254	463793804							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121188	CC(C)n1cc(Nc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)cn1	InChI=1S/C27H35N7O/c1-18(2)34-15-22(14-29-34)30-27-28-13-21-12-19(3)33(17-25(21)31-27)26(35)23-10-11-32(4)16-24(23)20-8-6-5-7-9-20/h5-9,13-15,18-19,23-24H,10-12,16-17H2,1-4H3,(H,28,30,31)/t19-,23+,24-/m1/s1	PIEQRGANCWMOJQ-VEXUSMLFSA-N	530319	WO2022064009, Compound 83::WO2022064009, Compound 89	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 794							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530319&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200255	463793805							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121189	CC(C)n1cc(Nc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)cn1	InChI=1S/C27H35N7O/c1-18(2)34-15-22(14-29-34)30-27-28-13-21-12-19(3)33(17-25(21)31-27)26(35)23-10-11-32(4)16-24(23)20-8-6-5-7-9-20/h5-9,13-15,18-19,23-24H,10-12,16-17H2,1-4H3,(H,28,30,31)/t19-,23+,24-/m1/s1	PIEQRGANCWMOJQ-VEXUSMLFSA-N	530319	WO2022064009, Compound 83::WO2022064009, Compound 89	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>200							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530319&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200255	463793805							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121190	CC(C)n1cc(Nc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)cn1	InChI=1S/C27H35N7O/c1-18(2)34-15-22(14-29-34)30-27-28-13-21-12-19(3)33(17-25(21)31-27)26(35)23-10-11-32(4)16-24(23)20-8-6-5-7-9-20/h5-9,13-15,18-19,23-24H,10-12,16-17H2,1-4H3,(H,28,30,31)/t19-,23+,24-/m1/s1	PIEQRGANCWMOJQ-VEXUSMLFSA-N	530319	WO2022064009, Compound 83::WO2022064009, Compound 89	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 794							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530319&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200255	463793805							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121191	CC(C)n1cc(Nc2ncc3C[C@@H](C)N(Cc3n2)C(=O)[C@H]2CCN(C)C[C@@H]2c2ccccc2)cn1	InChI=1S/C27H35N7O/c1-18(2)34-15-22(14-29-34)30-27-28-13-21-12-19(3)33(17-25(21)31-27)26(35)23-10-11-32(4)16-24(23)20-8-6-5-7-9-20/h5-9,13-15,18-19,23-24H,10-12,16-17H2,1-4H3,(H,28,30,31)/t19-,23+,24-/m1/s1	PIEQRGANCWMOJQ-VEXUSMLFSA-N	530319	WO2022064009, Compound 83::WO2022064009, Compound 89	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>200							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530319&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200255	463793805							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121192	C[C@@H]1Cc2cnc(NC(C)(C)c3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H37N7O/c1-19-13-21-14-29-27(32-28(2,3)22-15-30-34(5)16-22)31-25(21)18-35(19)26(36)23-11-12-33(4)17-24(23)20-9-7-6-8-10-20/h6-10,14-16,19,23-24H,11-13,17-18H2,1-5H3,(H,29,31,32)/t19-,23+,24-/m1/s1	SVCQGYRATHMIEE-VEXUSMLFSA-N	530321	WO2022064009, Compound 90	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 37							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530321	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530321&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200256	463793806							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121193	C[C@@H]1Cc2cnc(NC(C)(C)c3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H37N7O/c1-19-13-21-14-29-27(32-28(2,3)22-15-30-34(5)16-22)31-25(21)18-35(19)26(36)23-11-12-33(4)17-24(23)20-9-7-6-8-10-20/h6-10,14-16,19,23-24H,11-13,17-18H2,1-5H3,(H,29,31,32)/t19-,23+,24-/m1/s1	SVCQGYRATHMIEE-VEXUSMLFSA-N	530321	WO2022064009, Compound 90	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 27							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530321	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530321&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200256	463793806							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121194	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H31N7O/c1-17-11-19-12-26-25(28-20-13-27-31(3)14-20)29-23(19)16-32(17)24(33)21-9-10-30(2)15-22(21)18-7-5-4-6-8-18/h4-8,12-14,17,21-22H,9-11,15-16H2,1-3H3,(H,26,28,29)/t17-,21+,22-/m1/s1	ULPUTPYMWGDKDQ-VOQZNFBZSA-N	530318	WO2022064009, Compound 82::WO2022064009, Compound 91	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530318	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530318&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200254	463793804							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121195	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H31N7O/c1-17-11-19-12-26-25(28-20-13-27-31(3)14-20)29-23(19)16-32(17)24(33)21-9-10-30(2)15-22(21)18-7-5-4-6-8-18/h4-8,12-14,17,21-22H,9-11,15-16H2,1-3H3,(H,26,28,29)/t17-,21+,22-/m1/s1	ULPUTPYMWGDKDQ-VOQZNFBZSA-N	530318	WO2022064009, Compound 82::WO2022064009, Compound 91	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.14							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530318	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530318&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200254	463793804							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121196	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1ccc(C)nc1	InChI=1S/C26H36N6O2/c1-17-4-5-19(13-27-17)23-15-31(3)9-6-22(23)25(33)32-16-24-20(12-18(32)2)14-28-26(30-24)29-21-7-10-34-11-8-21/h4-5,13-14,18,21-23H,6-12,15-16H2,1-3H3,(H,28,29,30)/t18-,22-,23+/m1/s1	UPZHWOSGPQQMKV-YSZBQJHXSA-N	530323	WO2022064009, Compound 108	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 105							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530323&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200257	463793807							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121197	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1ccc(C)nc1	InChI=1S/C26H36N6O2/c1-17-4-5-19(13-27-17)23-15-31(3)9-6-22(23)25(33)32-16-24-20(12-18(32)2)14-28-26(30-24)29-21-7-10-34-11-8-21/h4-5,13-14,18,21-23H,6-12,15-16H2,1-3H3,(H,28,29,30)/t18-,22-,23+/m1/s1	UPZHWOSGPQQMKV-YSZBQJHXSA-N	530323	WO2022064009, Compound 108	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 20							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530323&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200257	463793807							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121198	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@@H]1CCN(C)C[C@H]1c1ccc(C)nc1	InChI=1S/C28H40N6O2/c1-18-5-6-20(14-29-18)25-16-33(3)12-11-24(25)27(35)34-17-26-21(13-19(34)2)15-30-28(32-26)31-22-7-9-23(36-4)10-8-22/h5-6,14-15,19,22-25H,7-13,16-17H2,1-4H3,(H,30,31,32)/t19-,22-,23-,24-,25+/m1/s1	GZSUGSQAQQXILA-YJMUNGTFSA-N	530324	WO2022064009, Compound 109	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530324	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530324&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200258	463793808							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121199	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(C)nc1	InChI=1S/C28H40N6O2/c1-18-5-6-20(14-29-18)25-16-33(3)12-11-24(25)27(35)34-17-26-21(13-19(34)2)15-30-28(32-26)31-22-7-9-23(36-4)10-8-22/h5-6,14-15,19,22-25H,7-13,16-17H2,1-4H3,(H,30,31,32)/t19-,22-,23-,24+,25-/m1/s1	GZSUGSQAQQXILA-WAKWQXKPSA-N	530325	WO2022064009, Compound 110	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530325&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200259	463793809							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121200	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(C)nc1	InChI=1S/C28H40N6O2/c1-18-5-6-20(14-29-18)25-16-33(3)12-11-24(25)27(35)34-17-26-21(13-19(34)2)15-30-28(32-26)31-22-7-9-23(36-4)10-8-22/h5-6,14-15,19,22-25H,7-13,16-17H2,1-4H3,(H,30,31,32)/t19-,22-,23-,24+,25-/m1/s1	GZSUGSQAQQXILA-WAKWQXKPSA-N	530325	WO2022064009, Compound 110	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 13							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530325&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200259	463793809							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121201	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)C1CCN(C)CC1C1CC1	InChI=1S/C23H35N5O2/c1-15-11-17-12-24-23(25-18-6-9-30-10-7-18)26-21(17)14-28(15)22(29)19-5-8-27(2)13-20(19)16-3-4-16/h12,15-16,18-20H,3-11,13-14H2,1-2H3,(H,24,25,26)/t15-,19?,20?/m1/s1	CXIDPTJAGRTYQO-APMMTJHUSA-N	530326	WO2022064009, Compound 111	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 214							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530326	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530326&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200260	463793810							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121202	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1C1CC1	InChI=1S/C23H35N5O2/c1-15-11-17-12-24-23(25-18-6-9-30-10-7-18)26-21(17)14-28(15)22(29)19-5-8-27(2)13-20(19)16-3-4-16/h12,15-16,18-20H,3-11,13-14H2,1-2H3,(H,24,25,26)/t15-,19-,20+/m1/s1	CXIDPTJAGRTYQO-YSGRDPCXSA-N	530327	WO2022064009, Compound 112	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530327	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530327&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200261	463793811							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121203	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1C1CC1	InChI=1S/C23H35N5O2/c1-15-11-17-12-24-23(25-18-6-9-30-10-7-18)26-21(17)14-28(15)22(29)19-5-8-27(2)13-20(19)16-3-4-16/h12,15-16,18-20H,3-11,13-14H2,1-2H3,(H,24,25,26)/t15-,19+,20-/m1/s1	CXIDPTJAGRTYQO-UIAACRFSSA-N	530328	WO2022064009, Compound 113	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 79							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530328	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530328&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200262	463793812							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121204	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(F)c(Cl)c1	InChI=1S/C26H33ClFN5O2/c1-16-11-18-13-29-26(30-19-6-9-35-10-7-19)31-24(18)15-33(16)25(34)20-5-8-32(2)14-21(20)17-3-4-23(28)22(27)12-17/h3-4,12-13,16,19-21H,5-11,14-15H2,1-2H3,(H,29,30,31)/t16-,20+,21-/m1/s1	WIWMWSFZWVAUMK-TYCQWZJGSA-N	530329	WO2022064009, Compound 114	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530329	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530329&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200263	463793813							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121205	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1C1CCOCC1	InChI=1S/C25H39N5O3/c1-17-13-19-14-26-25(27-20-6-11-33-12-7-20)28-23(19)16-30(17)24(31)21-3-8-29(2)15-22(21)18-4-9-32-10-5-18/h14,17-18,20-22H,3-13,15-16H2,1-2H3,(H,26,27,28)/t17-,21+,22-/m1/s1	CNWAAMSHAIHACL-VOQZNFBZSA-N	530330	WO2022064009, Compound 115	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 120							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530330	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530330&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200264	463793814							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121206	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1ccncc1	InChI=1S/C25H34N6O2/c1-17-13-19-14-27-25(28-20-6-11-33-12-7-20)29-23(19)16-31(17)24(32)21-5-10-30(2)15-22(21)18-3-8-26-9-4-18/h3-4,8-9,14,17,20-22H,5-7,10-13,15-16H2,1-2H3,(H,27,28,29)/t17-,21-,22+/m1/s1	YFIVXYKVZXRPAD-YHYVQYDKSA-N	530331	WO2022064009, Compound 116	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 37							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530331	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530331&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200265	463793815							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121207	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1cccnc1	InChI=1S/C25H34N6O2/c1-17-12-19-14-27-25(28-20-6-10-33-11-7-20)29-23(19)16-31(17)24(32)21-5-9-30(2)15-22(21)18-4-3-8-26-13-18/h3-4,8,13-14,17,20-22H,5-7,9-12,15-16H2,1-2H3,(H,27,28,29)/t17-,21-,22+/m1/s1	WSFJOHWKNPLIJN-YHYVQYDKSA-N	530332	WO2022064009, Compound 117	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 16							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530332	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530332&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200266	463793816							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121208	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(C)cc1	InChI=1S/C27H37N5O2/c1-18-4-6-20(7-5-18)24-16-31(3)11-8-23(24)26(33)32-17-25-21(14-19(32)2)15-28-27(30-25)29-22-9-12-34-13-10-22/h4-7,15,19,22-24H,8-14,16-17H2,1-3H3,(H,28,29,30)/t19-,23+,24-/m1/s1	DKTUJTJSJRBONN-VEXUSMLFSA-N	530333	WO2022064009, Compound 118	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 12							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530333	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530333&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200267	463793817							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121209	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(Cl)c1	InChI=1S/C26H34ClN5O2/c1-17-12-19-14-28-26(29-21-7-10-34-11-8-21)30-24(19)16-32(17)25(33)22-6-9-31(2)15-23(22)18-4-3-5-20(27)13-18/h3-5,13-14,17,21-23H,6-12,15-16H2,1-2H3,(H,28,29,30)/t17-,22+,23-/m1/s1	KWBAIYSDYBCMAA-MQNAVGNWSA-N	530334	WO2022064009, Compound 119	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 72							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530334	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530334&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200268	463793818							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121210	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(F)cc1	InChI=1S/C26H34FN5O2/c1-17-13-19-14-28-26(29-21-8-11-34-12-9-21)30-24(19)16-32(17)25(33)22-7-10-31(2)15-23(22)18-3-5-20(27)6-4-18/h3-6,14,17,21-23H,7-13,15-16H2,1-2H3,(H,28,29,30)/t17-,22+,23-/m1/s1	SAKVDYAGNDYVCG-MQNAVGNWSA-N	530335	WO2022064009, Compound 120::WO2022064009, Compound 93	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 12							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530335&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200269	463793819							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121211	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1ccc(Cl)c(F)c1	InChI=1S/C26H33ClFN5O2/c1-16-11-18-13-29-26(30-19-6-9-35-10-7-19)31-24(18)15-33(16)25(34)20-5-8-32(2)14-21(20)17-3-4-22(27)23(28)12-17/h3-4,12-13,16,19-21H,5-11,14-15H2,1-2H3,(H,29,30,31)/t16-,20-,21+/m1/s1	KMJFTFBBELZTFN-HBGVWJBISA-N	530336	WO2022064009, Compound 122a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530336&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200270	463793820							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121212	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(Cl)c(F)c1	InChI=1S/C26H33ClFN5O2/c1-16-11-18-13-29-26(30-19-6-9-35-10-7-19)31-24(18)15-33(16)25(34)20-5-8-32(2)14-21(20)17-3-4-22(27)23(28)12-17/h3-4,12-13,16,19-21H,5-11,14-15H2,1-2H3,(H,29,30,31)/t16-,20+,21-/m1/s1	KMJFTFBBELZTFN-TYCQWZJGSA-N	530337	WO2022064009, Compound 122b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 71							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530337	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530337&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200271	463793821							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121213	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(Cl)c(F)c1	InChI=1S/C26H33ClFN5O2/c1-16-11-18-13-29-26(30-19-6-9-35-10-7-19)31-24(18)15-33(16)25(34)20-5-8-32(2)14-21(20)17-3-4-22(27)23(28)12-17/h3-4,12-13,16,19-21H,5-11,14-15H2,1-2H3,(H,29,30,31)/t16-,20+,21-/m1/s1	KMJFTFBBELZTFN-TYCQWZJGSA-N	530337	WO2022064009, Compound 122b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.16							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530337	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530337&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200271	463793821							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121214	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1cccc(C)c1	InChI=1S/C26H33N7O/c1-17-6-5-7-19(10-17)23-15-31(3)9-8-22(23)25(34)33-16-24-20(11-18(33)2)12-27-26(30-24)29-21-13-28-32(4)14-21/h5-7,10,12-14,18,22-23H,8-9,11,15-16H2,1-4H3,(H,27,29,30)/t18-,22-,23+/m1/s1	FLAUIOGBWZNNGG-YSZBQJHXSA-N	530338	WO2022064009, Compound 125	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 339							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530338&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200272	463793822							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121215	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(C)c1	InChI=1S/C26H33N7O/c1-17-6-5-7-19(10-17)23-15-31(3)9-8-22(23)25(34)33-16-24-20(11-18(33)2)12-27-26(30-24)29-21-13-28-32(4)14-21/h5-7,10,12-14,18,22-23H,8-9,11,15-16H2,1-4H3,(H,27,29,30)/t18-,22+,23-/m1/s1	FLAUIOGBWZNNGG-YFXJRYMSSA-N	530339	WO2022064009, Compound 126	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 15							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530339&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200273	463793823							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121216	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(C)c1	InChI=1S/C26H33N7O/c1-17-6-5-7-19(10-17)23-15-31(3)9-8-22(23)25(34)33-16-24-20(11-18(33)2)12-27-26(30-24)29-21-13-28-32(4)14-21/h5-7,10,12-14,18,22-23H,8-9,11,15-16H2,1-4H3,(H,27,29,30)/t18-,22+,23-/m1/s1	FLAUIOGBWZNNGG-YFXJRYMSSA-N	530339	WO2022064009, Compound 126	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.72							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530339&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200273	463793823							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121217	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1cccc(OC(F)(F)F)c1	InChI=1S/C26H30F3N7O2/c1-16-9-18-11-30-25(32-19-12-31-35(3)13-19)33-23(18)15-36(16)24(37)21-7-8-34(2)14-22(21)17-5-4-6-20(10-17)38-26(27,28)29/h4-6,10-13,16,21-22H,7-9,14-15H2,1-3H3,(H,30,32,33)/t16-,21-,22+/m1/s1	ZYCOATOBQPSLRN-HVETUWLQSA-N	530340	WO2022064009, Compound 127	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 234							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530340&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200274	463793824							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121218	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1cccc(OC(F)(F)F)c1	InChI=1S/C26H30F3N7O2/c1-16-9-18-11-30-25(32-19-12-31-35(3)13-19)33-23(18)15-36(16)24(37)21-7-8-34(2)14-22(21)17-5-4-6-20(10-17)38-26(27,28)29/h4-6,10-13,16,21-22H,7-9,14-15H2,1-3H3,(H,30,32,33)/t16-,21-,22+/m1/s1	ZYCOATOBQPSLRN-HVETUWLQSA-N	530340	WO2022064009, Compound 127	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 76							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530340&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200274	463793824							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121219	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(OC(F)(F)F)c1	InChI=1S/C26H30F3N7O2/c1-16-9-18-11-30-25(32-19-12-31-35(3)13-19)33-23(18)15-36(16)24(37)21-7-8-34(2)14-22(21)17-5-4-6-20(10-17)38-26(27,28)29/h4-6,10-13,16,21-22H,7-9,14-15H2,1-3H3,(H,30,32,33)/t16-,21+,22-/m1/s1	ZYCOATOBQPSLRN-URZJWIJPSA-N	530341	WO2022064009, Compound 128	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 19							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530341&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200275	463793825							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121220	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(OC(F)(F)F)c1	InChI=1S/C26H30F3N7O2/c1-16-9-18-11-30-25(32-19-12-31-35(3)13-19)33-23(18)15-36(16)24(37)21-7-8-34(2)14-22(21)17-5-4-6-20(10-17)38-26(27,28)29/h4-6,10-13,16,21-22H,7-9,14-15H2,1-3H3,(H,30,32,33)/t16-,21+,22-/m1/s1	ZYCOATOBQPSLRN-URZJWIJPSA-N	530341	WO2022064009, Compound 128	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.76							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530341&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200275	463793825							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121221	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(c1)C(F)(F)F	InChI=1S/C26H30F3N7O/c1-16-9-18-11-30-25(32-20-12-31-35(3)13-20)33-23(18)15-36(16)24(37)21-7-8-34(2)14-22(21)17-5-4-6-19(10-17)26(27,28)29/h4-6,10-13,16,21-22H,7-9,14-15H2,1-3H3,(H,30,32,33)/t16-,21+,22-/m1/s1	GYBUJODTBQXUHX-URZJWIJPSA-N	530342	WO2022064009, Compound 129	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 12							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530342&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200276	463793826							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121222	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(c1)C(F)(F)F	InChI=1S/C26H30F3N7O/c1-16-9-18-11-30-25(32-20-12-31-35(3)13-20)33-23(18)15-36(16)24(37)21-7-8-34(2)14-22(21)17-5-4-6-19(10-17)26(27,28)29/h4-6,10-13,16,21-22H,7-9,14-15H2,1-3H3,(H,30,32,33)/t16-,21+,22-/m1/s1	GYBUJODTBQXUHX-URZJWIJPSA-N	530342	WO2022064009, Compound 129	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 4.90							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530342&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200276	463793826							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121223	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1ccccc1F	InChI=1S/C25H30FN7O/c1-16-10-17-11-27-25(29-18-12-28-32(3)13-18)30-23(17)15-33(16)24(34)20-8-9-31(2)14-21(20)19-6-4-5-7-22(19)26/h4-7,11-13,16,20-21H,8-10,14-15H2,1-3H3,(H,27,29,30)/t16-,20-,21+/m1/s1	LMHCBASAJOTSNR-HBGVWJBISA-N	530343	WO2022064009, Compound 130	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 38							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530343&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200277	463793827							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121224	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1ccccc1F	InChI=1S/C25H30FN7O/c1-16-10-17-11-27-25(29-18-12-28-32(3)13-18)30-23(17)15-33(16)24(34)20-8-9-31(2)14-21(20)19-6-4-5-7-22(19)26/h4-7,11-13,16,20-21H,8-10,14-15H2,1-3H3,(H,27,29,30)/t16-,20-,21+/m1/s1	LMHCBASAJOTSNR-HBGVWJBISA-N	530343	WO2022064009, Compound 130	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 7.94							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530343&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200277	463793827							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121225	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1F	InChI=1S/C25H30FN7O/c1-16-10-17-11-27-25(29-18-12-28-32(3)13-18)30-23(17)15-33(16)24(34)20-8-9-31(2)14-21(20)19-6-4-5-7-22(19)26/h4-7,11-13,16,20-21H,8-10,14-15H2,1-3H3,(H,27,29,30)/t16-,20+,21-/m1/s1	LMHCBASAJOTSNR-TYCQWZJGSA-N	530344	WO2022064009, Compound 131	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 62							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530344&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200278	463793828							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121226	C[C@@H]1Cc2cnc(Nc3cnn(C)c3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1F	InChI=1S/C25H30FN7O/c1-16-10-17-11-27-25(29-18-12-28-32(3)13-18)30-23(17)15-33(16)24(34)20-8-9-31(2)14-21(20)19-6-4-5-7-22(19)26/h4-7,11-13,16,20-21H,8-10,14-15H2,1-3H3,(H,27,29,30)/t16-,20+,21-/m1/s1	LMHCBASAJOTSNR-TYCQWZJGSA-N	530344	WO2022064009, Compound 131	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.12							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530344&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200278	463793828							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121227	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1ccc(F)cc1	InChI=1S/C26H34FN5O2/c1-17-13-19-14-28-26(29-21-8-11-34-12-9-21)30-24(19)16-32(17)25(33)22-7-10-31(2)15-23(22)18-3-5-20(27)6-4-18/h3-6,14,17,21-23H,7-13,15-16H2,1-2H3,(H,28,29,30)/t17-,22-,23+/m1/s1	SAKVDYAGNDYVCG-ZQMYSKGWSA-N	530345	WO2022064009, Compound 92a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 7762							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530345&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200279	463793829							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121228	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1ccc(F)cc1	InChI=1S/C26H34FN5O2/c1-17-13-19-14-28-26(29-21-8-11-34-12-9-21)30-24(19)16-32(17)25(33)22-7-10-31(2)15-23(22)18-3-5-20(27)6-4-18/h3-6,14,17,21-23H,7-13,15-16H2,1-2H3,(H,28,29,30)/t17-,22-,23+/m1/s1	SAKVDYAGNDYVCG-ZQMYSKGWSA-N	530345	WO2022064009, Compound 92a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 12							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530345&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200279	463793829							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121229	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(F)cc1	InChI=1S/C26H34FN5O2/c1-17-13-19-14-28-26(29-21-8-11-34-12-9-21)30-24(19)16-32(17)25(33)22-7-10-31(2)15-23(22)18-3-5-20(27)6-4-18/h3-6,14,17,21-23H,7-13,15-16H2,1-2H3,(H,28,29,30)/t17-,22+,23-/m1/s1	SAKVDYAGNDYVCG-MQNAVGNWSA-N	530335	WO2022064009, Compound 120::WO2022064009, Compound 93	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530335&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200269	463793819							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121230	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(F)cc1	InChI=1S/C26H34FN5O2/c1-17-13-19-14-28-26(29-21-8-11-34-12-9-21)30-24(19)16-32(17)25(33)22-7-10-31(2)15-23(22)18-3-5-20(27)6-4-18/h3-6,14,17,21-23H,7-13,15-16H2,1-2H3,(H,28,29,30)/t17-,22+,23-/m1/s1	SAKVDYAGNDYVCG-MQNAVGNWSA-N	530335	WO2022064009, Compound 120::WO2022064009, Compound 93	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.02							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530335&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200269	463793819							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121231	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)C1CCN(C)CC1c1ccnc(C)c1	InChI=1S/C26H36N6O2/c1-17-12-19(4-8-27-17)23-15-31(3)9-5-22(23)25(33)32-16-24-20(13-18(32)2)14-28-26(30-24)29-21-6-10-34-11-7-21/h4,8,12,14,18,21-23H,5-7,9-11,13,15-16H2,1-3H3,(H,28,29,30)/t18-,22?,23?/m1/s1	LWRJSVITUMBUQB-WDGBRCNXSA-N	530347	WO2022064009, Compound 101	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 21							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530347&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200280	463793830							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121232	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1ccnc(C)c1	InChI=1S/C26H36N6O2/c1-17-12-19(4-8-27-17)23-15-31(3)9-5-22(23)25(33)32-16-24-20(13-18(32)2)14-28-26(30-24)29-21-6-10-34-11-7-21/h4,8,12,14,18,21-23H,5-7,9-11,13,15-16H2,1-3H3,(H,28,29,30)/t18-,22-,23+/m1/s1	LWRJSVITUMBUQB-YSZBQJHXSA-N	530348	WO2022064009, Compound 102	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 105							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530348&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200281	463793831							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121233	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1ccnc(C)c1	InChI=1S/C26H36N6O2/c1-17-12-19(4-8-27-17)23-15-31(3)9-5-22(23)25(33)32-16-24-20(13-18(32)2)14-28-26(30-24)29-21-6-10-34-11-7-21/h4,8,12,14,18,21-23H,5-7,9-11,13,15-16H2,1-3H3,(H,28,29,30)/t18-,22-,23+/m1/s1	LWRJSVITUMBUQB-YSZBQJHXSA-N	530348	WO2022064009, Compound 102	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 20							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530348&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200281	463793831							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121234	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccnc(C)c1	InChI=1S/C26H36N6O2/c1-17-12-19(4-8-27-17)23-15-31(3)9-5-22(23)25(33)32-16-24-20(13-18(32)2)14-28-26(30-24)29-21-6-10-34-11-7-21/h4,8,12,14,18,21-23H,5-7,9-11,13,15-16H2,1-3H3,(H,28,29,30)/t18-,22+,23-/m1/s1	LWRJSVITUMBUQB-YFXJRYMSSA-N	530349	WO2022064009, Compound 103::WO2022064009, Compound 107	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530349&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200282	463793832							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121235	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)C1CCN(C)CC1c1ccnc(C)c1	InChI=1S/C28H40N6O2/c1-18-13-20(9-11-29-18)25-16-33(3)12-10-24(25)27(35)34-17-26-21(14-19(34)2)15-30-28(32-26)31-22-5-7-23(36-4)8-6-22/h9,11,13,15,19,22-25H,5-8,10,12,14,16-17H2,1-4H3,(H,30,31,32)/t19-,22-,23-,24?,25?/m1/s1	VXWBPLNIVFITGI-ZMWOOYMPSA-N	530350	WO2022064009, Compound 104	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 10							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530350&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200283	463793833							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121236	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@@H]1CCN(C)C[C@H]1c1ccnc(C)c1	InChI=1S/C28H40N6O2/c1-18-13-20(9-11-29-18)25-16-33(3)12-10-24(25)27(35)34-17-26-21(14-19(34)2)15-30-28(32-26)31-22-5-7-23(36-4)8-6-22/h9,11,13,15,19,22-25H,5-8,10,12,14,16-17H2,1-4H3,(H,30,31,32)/t19-,22-,23-,24-,25+/m1/s1	VXWBPLNIVFITGI-YJMUNGTFSA-N	530351	WO2022064009, Compound 105	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530351&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200284	463793834							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121237	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@@H]1CCN(C)C[C@H]1c1ccnc(C)c1	InChI=1S/C28H40N6O2/c1-18-13-20(9-11-29-18)25-16-33(3)12-10-24(25)27(35)34-17-26-21(14-19(34)2)15-30-28(32-26)31-22-5-7-23(36-4)8-6-22/h9,11,13,15,19,22-25H,5-8,10,12,14,16-17H2,1-4H3,(H,30,31,32)/t19-,22-,23-,24-,25+/m1/s1	VXWBPLNIVFITGI-YJMUNGTFSA-N	530351	WO2022064009, Compound 105	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 10.00							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530351&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200284	463793834							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121238	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccnc(C)c1	InChI=1S/C28H40N6O2/c1-18-13-20(9-11-29-18)25-16-33(3)12-10-24(25)27(35)34-17-26-21(14-19(34)2)15-30-28(32-26)31-22-5-7-23(36-4)8-6-22/h9,11,13,15,19,22-25H,5-8,10,12,14,16-17H2,1-4H3,(H,30,31,32)/t19-,22-,23-,24+,25-/m1/s1	VXWBPLNIVFITGI-WAKWQXKPSA-N	530352	WO2022064009, Compound 106	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6026							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530352&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200285	463793835							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121239	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccnc(C)c1	InChI=1S/C26H36N6O2/c1-17-12-19(4-8-27-17)23-15-31(3)9-5-22(23)25(33)32-16-24-20(13-18(32)2)14-28-26(30-24)29-21-6-10-34-11-7-21/h4,8,12,14,18,21-23H,5-7,9-11,13,15-16H2,1-3H3,(H,28,29,30)/t18-,22+,23-/m1/s1	LWRJSVITUMBUQB-YFXJRYMSSA-N	530349	WO2022064009, Compound 103::WO2022064009, Compound 107	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530349&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200282	463793832							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121240	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(Cl)cc1	InChI=1S/C26H34ClN5O2/c1-17-13-19-14-28-26(29-21-8-11-34-12-9-21)30-24(19)16-32(17)25(33)22-7-10-31(2)15-23(22)18-3-5-20(27)6-4-18/h3-6,14,17,21-23H,7-13,15-16H2,1-2H3,(H,28,29,30)/t17-,22+,23-/m1/s1	ARQYNVSOBQDQFW-MQNAVGNWSA-N	530354	WO2022064009, Compound 132	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530354&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200286	463793836							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121241	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccc(Cl)cc1	InChI=1S/C26H34ClN5O2/c1-17-13-19-14-28-26(29-21-8-11-34-12-9-21)30-24(19)16-32(17)25(33)22-7-10-31(2)15-23(22)18-3-5-20(27)6-4-18/h3-6,14,17,21-23H,7-13,15-16H2,1-2H3,(H,28,29,30)/t17-,22+,23-/m1/s1	ARQYNVSOBQDQFW-MQNAVGNWSA-N	530354	WO2022064009, Compound 132	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.63							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530354&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200286	463793836							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121242	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(F)c1	InChI=1S/C26H34FN5O2/c1-17-12-19-14-28-26(29-21-7-10-34-11-8-21)30-24(19)16-32(17)25(33)22-6-9-31(2)15-23(22)18-4-3-5-20(27)13-18/h3-5,13-14,17,21-23H,6-12,15-16H2,1-2H3,(H,28,29,30)/t17-,22+,23-/m1/s1	ILJAKXMJRBDMTJ-MQNAVGNWSA-N	530355	WO2022064009, Compound 133	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 12							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530355&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200287	463793837							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121243	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(F)c1	InChI=1S/C26H34FN5O2/c1-17-12-19-14-28-26(29-21-7-10-34-11-8-21)30-24(19)16-32(17)25(33)22-6-9-31(2)15-23(22)18-4-3-5-20(27)13-18/h3-5,13-14,17,21-23H,6-12,15-16H2,1-2H3,(H,28,29,30)/t17-,22+,23-/m1/s1	ILJAKXMJRBDMTJ-MQNAVGNWSA-N	530355	WO2022064009, Compound 133	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8.13							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530355&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200287	463793837							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121244	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(C)c1	InChI=1S/C27H37N5O2/c1-18-5-4-6-20(13-18)24-16-31(3)10-7-23(24)26(33)32-17-25-21(14-19(32)2)15-28-27(30-25)29-22-8-11-34-12-9-22/h4-6,13,15,19,22-24H,7-12,14,16-17H2,1-3H3,(H,28,29,30)/t19-,23+,24-/m1/s1	KJCDDUNOLUHFCC-VEXUSMLFSA-N	530356	WO2022064009, Compound 134	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530356&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200288	463793838							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121245	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(C)c1	InChI=1S/C27H37N5O2/c1-18-5-4-6-20(13-18)24-16-31(3)10-7-23(24)26(33)32-17-25-21(14-19(32)2)15-28-27(30-25)29-22-8-11-34-12-9-22/h4-6,13,15,19,22-24H,7-12,14,16-17H2,1-3H3,(H,28,29,30)/t19-,23+,24-/m1/s1	KJCDDUNOLUHFCC-VEXUSMLFSA-N	530356	WO2022064009, Compound 134	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.16							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530356&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200288	463793838							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121246	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1cccc(C)c1	InChI=1S/C27H35N7O/c1-18-6-5-7-20(12-18)24-16-32(3)10-9-23(24)26(35)34-17-25-21(13-19(34)2)14-28-27(30-25)29-15-22-8-11-33(4)31-22/h5-8,11-12,14,19,23-24H,9-10,13,15-17H2,1-4H3,(H,28,29,30)/t19-,23-,24+/m1/s1	YBDRYPNMGCUBKV-FOVJLYNBSA-N	530357	WO2022064009, Compound 136::WO2022064009, Compound 148	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530357&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200289	463793839							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121247	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1cccc(C)c1	InChI=1S/C27H35N7O/c1-18-6-5-7-20(12-18)24-16-32(3)10-9-23(24)26(35)34-17-25-21(13-19(34)2)14-28-27(30-25)29-15-22-8-11-33(4)31-22/h5-8,11-12,14,19,23-24H,9-10,13,15-17H2,1-4H3,(H,28,29,30)/t19-,23-,24+/m1/s1	YBDRYPNMGCUBKV-FOVJLYNBSA-N	530357	WO2022064009, Compound 136::WO2022064009, Compound 148	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 16							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530357&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200289	463793839							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121248	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1cccc(C)c1	InChI=1S/C27H37N5O2/c1-18-5-4-6-20(13-18)24-16-31(3)10-7-23(24)26(33)32-17-25-21(14-19(32)2)15-28-27(30-25)29-22-8-11-34-12-9-22/h4-6,13,15,19,22-24H,7-12,14,16-17H2,1-3H3,(H,28,29,30)/t19-,23-,24+/m1/s1	KJCDDUNOLUHFCC-FOVJLYNBSA-N	530358	WO2022064009, Compound 137	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 457							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530358	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530358&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200290	463793840							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121249	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1C(F)F	InChI=1S/C27H33F2N7O/c1-17-12-18-13-30-27(31-14-19-8-11-35(3)33-19)32-24(18)16-36(17)26(37)22-9-10-34(2)15-23(22)20-6-4-5-7-21(20)25(28)29/h4-8,11,13,17,22-23,25H,9-10,12,14-16H2,1-3H3,(H,30,31,32)/t17-,22+,23-/m1/s1	GJCPYBDEQWSUOU-MQNAVGNWSA-N	530359	WO2022064009, Compound 139	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 91							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530359&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200291	463793841							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121250	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1C(F)F	InChI=1S/C27H33F2N7O/c1-17-12-18-13-30-27(31-14-19-8-11-35(3)33-19)32-24(18)16-36(17)26(37)22-9-10-34(2)15-23(22)20-6-4-5-7-21(20)25(28)29/h4-8,11,13,17,22-23,25H,9-10,12,14-16H2,1-3H3,(H,30,31,32)/t17-,22+,23-/m1/s1	GJCPYBDEQWSUOU-MQNAVGNWSA-N	530359	WO2022064009, Compound 139	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 49							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530359&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200291	463793841							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121251	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1C(F)(F)F	InChI=1S/C21H30F3N5O2/c1-13-9-14-10-25-20(26-15-4-7-31-8-5-15)27-18(14)12-29(13)19(30)16-3-6-28(2)11-17(16)21(22,23)24/h10,13,15-17H,3-9,11-12H2,1-2H3,(H,25,26,27)/t13-,16-,17-/m1/s1	CMWXFIQGYCBAMP-KBRIMQKVSA-N	530360	WO2022064009, Compound 140a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1288							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530360	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530360&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200292	463793842							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121252	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1C(F)(F)F	InChI=1S/C23H28F3N5O/c1-15-10-17-12-28-22(27-11-16-6-4-3-5-7-16)29-20(17)14-31(15)21(32)18-8-9-30(2)13-19(18)23(24,25)26/h3-7,12,15,18-19H,8-11,13-14H2,1-2H3,(H,27,28,29)/t15-,18-,19-/m1/s1	SHZLKNLAGHGOPG-ATZDWAIDSA-N	530361	WO2022064009, Compound 141	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 40							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530361&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200293	463793843							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121253	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1C(F)(F)F	InChI=1S/C23H28F3N5O/c1-15-10-17-12-28-22(27-11-16-6-4-3-5-7-16)29-20(17)14-31(15)21(32)18-8-9-30(2)13-19(18)23(24,25)26/h3-7,12,15,18-19H,8-11,13-14H2,1-2H3,(H,27,28,29)/t15-,18-,19-/m1/s1	SHZLKNLAGHGOPG-ATZDWAIDSA-N	530361	WO2022064009, Compound 141	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8.51							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530361&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200293	463793843							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121254	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1C(F)(F)F	InChI=1S/C23H28F3N5O/c1-15-10-17-12-28-22(27-11-16-6-4-3-5-7-16)29-20(17)14-31(15)21(32)18-8-9-30(2)13-19(18)23(24,25)26/h3-7,12,15,18-19H,8-11,13-14H2,1-2H3,(H,27,28,29)/t15-,18+,19+/m1/s1	SHZLKNLAGHGOPG-MNEFBYGVSA-N	530362	WO2022064009, Compound 142	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2951							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530362&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200294	463793844							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121255	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1C(F)(F)F	InChI=1S/C21H28F3N7O/c1-13-8-14-9-25-20(26-10-15-4-7-30(3)28-15)27-18(14)12-31(13)19(32)16-5-6-29(2)11-17(16)21(22,23)24/h4,7,9,13,16-17H,5-6,8,10-12H2,1-3H3,(H,25,26,27)/t13-,16+,17+/m1/s1	BYNLQCAMWHJCMB-COXVUDFISA-N	530363	WO2022064009, Compound 143	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530363&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200295	463793845							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121256	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1C(F)(F)F	InChI=1S/C21H28F3N7O/c1-13-8-14-9-25-20(26-10-15-4-7-30(3)28-15)27-18(14)12-31(13)19(32)16-5-6-29(2)11-17(16)21(22,23)24/h4,7,9,13,16-17H,5-6,8,10-12H2,1-3H3,(H,25,26,27)/t13-,16+,17+/m1/s1	BYNLQCAMWHJCMB-COXVUDFISA-N	530363	WO2022064009, Compound 143	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8.91							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530363&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200295	463793845							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121257	C[C@@H]1Cc2cnc(N[C@H]3CCCNC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1C(F)(F)F	InChI=1S/C21H31F3N6O/c1-13-8-14-9-26-20(27-15-4-3-6-25-10-15)28-18(14)12-30(13)19(31)16-5-7-29(2)11-17(16)21(22,23)24/h9,13,15-17,25H,3-8,10-12H2,1-2H3,(H,26,27,28)/t13-,15+,16+,17+/m1/s1	LPIWCQXQOBRCFD-IWCQGFGOSA-N	530364	WO2022064009, Compound 144	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530364&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200296	463793846							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121258	C[C@@H]1Cc2cnc(N[C@H]3CCCNC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1C(F)(F)F	InChI=1S/C21H31F3N6O/c1-13-8-14-9-26-20(27-15-4-3-6-25-10-15)28-18(14)12-30(13)19(31)16-5-7-29(2)11-17(16)21(22,23)24/h9,13,15-17,25H,3-8,10-12H2,1-2H3,(H,26,27,28)/t13-,15+,16+,17+/m1/s1	LPIWCQXQOBRCFD-IWCQGFGOSA-N	530364	WO2022064009, Compound 144	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 10.00							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530364&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200296	463793846							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121259	C[C@@H]1CN(C)CC[C@H]1C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C21H33N5O2/c1-14-12-25(3)7-4-18(14)20(27)26-13-19-16(10-15(26)2)11-22-21(24-19)23-17-5-8-28-9-6-17/h11,14-15,17-18H,4-10,12-13H2,1-3H3,(H,22,23,24)/t14-,15-,18-/m1/s1	GOFUIUCOUBGEQK-IIDMSEBBSA-N	530365	WO2022064009, Compound 145	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 68							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530365	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530365&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200297	463793847							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121260	C[C@@H]1CN(C)CC[C@H]1C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C21H33N5O2/c1-14-12-25(3)7-4-18(14)20(27)26-13-19-16(10-15(26)2)11-22-21(24-19)23-17-5-8-28-9-6-17/h11,14-15,17-18H,4-10,12-13H2,1-3H3,(H,22,23,24)/t14-,15-,18-/m1/s1	GOFUIUCOUBGEQK-IIDMSEBBSA-N	530365	WO2022064009, Compound 145	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 100							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530365	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530365&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200297	463793847							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121261	C[C@H]1CN(C)CC[C@@H]1C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C21H33N5O2/c1-14-12-25(3)7-4-18(14)20(27)26-13-19-16(10-15(26)2)11-22-21(24-19)23-17-5-8-28-9-6-17/h11,14-15,17-18H,4-10,12-13H2,1-3H3,(H,22,23,24)/t14-,15+,18-/m0/s1	GOFUIUCOUBGEQK-DAYGRLMNSA-N	530366	WO2022064009, Compound 146	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530366&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200298	463793848							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121262	C[C@H]1CN(C)CC[C@@H]1C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C21H33N5O2/c1-14-12-25(3)7-4-18(14)20(27)26-13-19-16(10-15(26)2)11-22-21(24-19)23-17-5-8-28-9-6-17/h11,14-15,17-18H,4-10,12-13H2,1-3H3,(H,22,23,24)/t14-,15+,18-/m0/s1	GOFUIUCOUBGEQK-DAYGRLMNSA-N	530366	WO2022064009, Compound 146	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 17							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530366&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200298	463793848							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121263	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1cccc(C)c1	InChI=1S/C27H35N7O/c1-18-6-5-7-20(12-18)24-16-32(3)10-9-23(24)26(35)34-17-25-21(13-19(34)2)14-28-27(30-25)29-15-22-8-11-33(4)31-22/h5-8,11-12,14,19,23-24H,9-10,13,15-17H2,1-4H3,(H,28,29,30)/t19-,23-,24+/m1/s1	YBDRYPNMGCUBKV-FOVJLYNBSA-N	530357	WO2022064009, Compound 136::WO2022064009, Compound 148	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530357&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200289	463793839							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121264	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@@H]1CCN(C)C[C@H]1c1cccc(C)c1	InChI=1S/C27H35N7O/c1-18-6-5-7-20(12-18)24-16-32(3)10-9-23(24)26(35)34-17-25-21(13-19(34)2)14-28-27(30-25)29-15-22-8-11-33(4)31-22/h5-8,11-12,14,19,23-24H,9-10,13,15-17H2,1-4H3,(H,28,29,30)/t19-,23-,24+/m1/s1	YBDRYPNMGCUBKV-FOVJLYNBSA-N	530357	WO2022064009, Compound 136::WO2022064009, Compound 148	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1.38							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530357&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200289	463793839							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121265	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1cccc(C)c1	InChI=1S/C27H35N7O/c1-18-6-5-7-20(12-18)24-16-32(3)10-9-23(24)26(35)34-17-25-21(13-19(34)2)14-28-27(30-25)29-15-22-8-11-33(4)31-22/h5-8,11-12,14,19,23-24H,9-10,13,15-17H2,1-4H3,(H,28,29,30)/t19-,23+,24-/m1/s1	YBDRYPNMGCUBKV-VEXUSMLFSA-N	530368	WO2022064009, Compound 149	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5012							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530368	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530368&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200299	463793849							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121266	CCN1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(NCc3ccn(C)n3)ncc2C[C@H]1C	InChI=1S/C28H37N7O/c1-5-34-12-10-24(25(17-34)21-8-6-7-19(2)13-21)27(36)35-18-26-22(14-20(35)3)15-29-28(31-26)30-16-23-9-11-33(4)32-23/h6-9,11,13,15,20,24-25H,5,10,12,14,16-18H2,1-4H3,(H,29,30,31)/t20-,24+,25-/m1/s1	FYWXDPDFNKAURG-DCEDVJGZSA-N	530369	WO2022064009, Compound 150	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530369&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200300	463793850							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121267	CCN1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(NCc3ccn(C)n3)ncc2C[C@H]1C	InChI=1S/C28H37N7O/c1-5-34-12-10-24(25(17-34)21-8-6-7-19(2)13-21)27(36)35-18-26-22(14-20(35)3)15-29-28(31-26)30-16-23-9-11-33(4)32-23/h6-9,11,13,15,20,24-25H,5,10,12,14,16-18H2,1-4H3,(H,29,30,31)/t20-,24+,25-/m1/s1	FYWXDPDFNKAURG-DCEDVJGZSA-N	530369	WO2022064009, Compound 150	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.16							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530369&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200300	463793850							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121268	C[C@H]1CN([C@H](C)c2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-16-32(26(33)22-9-12-31(3)17-24(22)20-7-5-4-6-8-20)19(2)25-23(18)15-28-27(30-25)29-21-10-13-34-14-11-21/h4-8,15,18-19,21-22,24H,9-14,16-17H2,1-3H3,(H,28,29,30)/t18-,19+,22-,24+/m0/s1	JHWWIMXJPOHWHC-SMKKKYSBSA-N	530370	WO2022064009, Compound 180a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530370&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200301	463793851							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121269	C[C@H]1CN([C@H](C)c2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-16-32(26(33)22-9-12-31(3)17-24(22)20-7-5-4-6-8-20)19(2)25-23(18)15-28-27(30-25)29-21-10-13-34-14-11-21/h4-8,15,18-19,21-22,24H,9-14,16-17H2,1-3H3,(H,28,29,30)/t18-,19+,22-,24+/m0/s1	JHWWIMXJPOHWHC-SMKKKYSBSA-N	530370	WO2022064009, Compound 180a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.09							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530370&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200301	463793851							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121270	C[C@@H]1CN([C@@H](C)c2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-16-32(26(33)22-9-12-31(3)17-24(22)20-7-5-4-6-8-20)19(2)25-23(18)15-28-27(30-25)29-21-10-13-34-14-11-21/h4-8,15,18-19,21-22,24H,9-14,16-17H2,1-3H3,(H,28,29,30)/t18-,19+,22+,24-/m1/s1	JHWWIMXJPOHWHC-KFELQJHASA-N	530371	WO2022064009, Compound 180b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2239							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530371	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530371&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200302	463793852							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121271	C[C@H]1CN([C@@H](C)c2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-16-32(26(33)22-9-12-31(3)17-24(22)20-7-5-4-6-8-20)19(2)25-23(18)15-28-27(30-25)29-21-10-13-34-14-11-21/h4-8,15,18-19,21-22,24H,9-14,16-17H2,1-3H3,(H,28,29,30)/t18-,19-,22-,24+/m0/s1	JHWWIMXJPOHWHC-GXBNZEJLSA-N	530372	WO2022064009, Compound 181	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 126							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530372&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200303	463793853							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121272	C[C@H]1CN([C@@H](C)c2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-16-32(26(33)22-9-12-31(3)17-24(22)20-7-5-4-6-8-20)19(2)25-23(18)15-28-27(30-25)29-21-10-13-34-14-11-21/h4-8,15,18-19,21-22,24H,9-14,16-17H2,1-3H3,(H,28,29,30)/t18-,19-,22-,24+/m0/s1	JHWWIMXJPOHWHC-GXBNZEJLSA-N	530372	WO2022064009, Compound 181	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 105							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530372&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200303	463793853							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121273	C[C@@H]1CN([C@H](C)c2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-16-32(26(33)22-9-12-31(3)17-24(22)20-7-5-4-6-8-20)19(2)25-23(18)15-28-27(30-25)29-21-10-13-34-14-11-21/h4-8,15,18-19,21-22,24H,9-14,16-17H2,1-3H3,(H,28,29,30)/t18-,19-,22+,24-/m1/s1	JHWWIMXJPOHWHC-WDOIYZOTSA-N	530373	WO2022064009, Compound 182	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 724							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530373&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200304	463793854							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121274	C[C@H]1N(CCc2cnc(NC3CCOCC3)nc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-24-20(16-27-26(29-24)28-21-10-14-33-15-11-21)8-13-31(18)25(32)22-9-12-30(2)17-23(22)19-6-4-3-5-7-19/h3-7,16,18,21-23H,8-15,17H2,1-2H3,(H,27,28,29)/t18-,22+,23-/m1/s1	KFQNEGIMZLDZDE-YFXJRYMSSA-N	530374	WO2022064009, Compound 183	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530374&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200305	463793855							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121275	C[C@@H]1N(CCc2cnc(NC3CCOCC3)nc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-24-20(16-27-26(29-24)28-21-10-14-33-15-11-21)8-13-31(18)25(32)22-9-12-30(2)17-23(22)19-6-4-3-5-7-19/h3-7,16,18,21-23H,8-15,17H2,1-2H3,(H,27,28,29)/t18-,22-,23+/m0/s1	KFQNEGIMZLDZDE-OFAXGOBFSA-N	530375	WO2022064009, Compound 184	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 26							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530375&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200306	463793856							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121276	COCCN1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(NCc3ccn(C)n3)ncc2C[C@H]1C	InChI=1S/C29H39N7O2/c1-20-6-5-7-22(14-20)26-18-35(12-13-38-4)11-9-25(26)28(37)36-19-27-23(15-21(36)2)16-30-29(32-27)31-17-24-8-10-34(3)33-24/h5-8,10,14,16,21,25-26H,9,11-13,15,17-19H2,1-4H3,(H,30,31,32)/t21-,25+,26-/m1/s1	IWCXJSVXAYKJQN-QGUKFAFCSA-N	530376	WO2022064009, Compound 151	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530376&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200307	463793857							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121277	COCCN1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(NCc3ccn(C)n3)ncc2C[C@H]1C	InChI=1S/C29H39N7O2/c1-20-6-5-7-22(14-20)26-18-35(12-13-38-4)11-9-25(26)28(37)36-19-27-23(15-21(36)2)16-30-29(32-27)31-17-24-8-10-34(3)33-24/h5-8,10,14,16,21,25-26H,9,11-13,15,17-19H2,1-4H3,(H,30,31,32)/t21-,25+,26-/m1/s1	IWCXJSVXAYKJQN-QGUKFAFCSA-N	530376	WO2022064009, Compound 151	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.31							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530376&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200307	463793857							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121278	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(CCO)C[C@@H]1c1cccc(C)c1	InChI=1S/C30H37N5O2/c1-21-7-6-10-24(15-21)27-19-34(13-14-36)12-11-26(27)29(37)35-20-28-25(16-22(35)2)18-32-30(33-28)31-17-23-8-4-3-5-9-23/h3-10,15,18,22,26-27,36H,11-14,16-17,19-20H2,1-2H3,(H,31,32,33)/t22-,26+,27-/m1/s1	OSBNEPHRHGJQGZ-VYCLJVNGSA-N	530377	WO2022064009, Compound 152	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530377&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200308	463793858							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121279	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(CCO)C[C@@H]1c1cccc(C)c1	InChI=1S/C30H37N5O2/c1-21-7-6-10-24(15-21)27-19-34(13-14-36)12-11-26(27)29(37)35-20-28-25(16-22(35)2)18-32-30(33-28)31-17-23-8-4-3-5-9-23/h3-10,15,18,22,26-27,36H,11-14,16-17,19-20H2,1-2H3,(H,31,32,33)/t22-,26+,27-/m1/s1	OSBNEPHRHGJQGZ-VYCLJVNGSA-N	530377	WO2022064009, Compound 152	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 4.37							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530377&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200308	463793858							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121280	COCCN1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(NCc3ccccc3)ncc2C[C@H]1C	InChI=1S/C31H39N5O2/c1-22-8-7-11-25(16-22)28-20-35(14-15-38-3)13-12-27(28)30(37)36-21-29-26(17-23(36)2)19-33-31(34-29)32-18-24-9-5-4-6-10-24/h4-11,16,19,23,27-28H,12-15,17-18,20-21H2,1-3H3,(H,32,33,34)/t23-,27+,28-/m1/s1	LYPGXSPBDFHGTG-KEKPKEOLSA-N	530378	WO2022064009, Compound 153	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530378&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200309	463793859							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121281	COCCN1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(NCc3ccccc3)ncc2C[C@H]1C	InChI=1S/C31H39N5O2/c1-22-8-7-11-25(16-22)28-20-35(14-15-38-3)13-12-27(28)30(37)36-21-29-26(17-23(36)2)19-33-31(34-29)32-18-24-9-5-4-6-10-24/h4-11,16,19,23,27-28H,12-15,17-18,20-21H2,1-3H3,(H,32,33,34)/t23-,27+,28-/m1/s1	LYPGXSPBDFHGTG-KEKPKEOLSA-N	530378	WO2022064009, Compound 153	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.92							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530378&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200309	463793859							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121282	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H33N5O/c1-20-15-23-17-30-28(29-16-21-9-5-3-6-10-21)31-26(23)19-33(20)27(34)24-13-14-32(2)18-25(24)22-11-7-4-8-12-22/h3-12,17,20,24-25H,13-16,18-19H2,1-2H3,(H,29,30,31)/t20-,24+,25-/m1/s1	OHPIHQNDZSUYLV-DCEDVJGZSA-N	530266	WO2022064009, Compound 154::WO2022064009, Compound 43	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530266&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200208	463793756							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121283	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H33N5O/c1-20-15-23-17-30-28(29-16-21-9-5-3-6-10-21)31-26(23)19-33(20)27(34)24-13-14-32(2)18-25(24)22-11-7-4-8-12-22/h3-12,17,20,24-25H,13-16,18-19H2,1-2H3,(H,29,30,31)/t20-,24+,25-/m1/s1	OHPIHQNDZSUYLV-DCEDVJGZSA-N	530266	WO2022064009, Compound 154::WO2022064009, Compound 43	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.51							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530266&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200208	463793756							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121284	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(CC2COC2)C[C@@H]1c1ccccc1	InChI=1S/C31H37N5O2/c1-22-14-26-16-33-31(32-15-23-8-4-2-5-9-23)34-29(26)19-36(22)30(37)27-12-13-35(17-24-20-38-21-24)18-28(27)25-10-6-3-7-11-25/h2-11,16,22,24,27-28H,12-15,17-21H2,1H3,(H,32,33,34)/t22-,27+,28-/m1/s1	ANXJNRMEWJLRAK-KKVCJECGSA-N	530380	WO2022064009, Compound 155	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530380&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200310	463793860							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121285	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=O)[C@H]1CCN(CC2COC2)C[C@@H]1c1ccccc1	InChI=1S/C31H37N5O2/c1-22-14-26-16-33-31(32-15-23-8-4-2-5-9-23)34-29(26)19-36(22)30(37)27-12-13-35(17-24-20-38-21-24)18-28(27)25-10-6-3-7-11-25/h2-11,16,22,24,27-28H,12-15,17-21H2,1H3,(H,32,33,34)/t22-,27+,28-/m1/s1	ANXJNRMEWJLRAK-KKVCJECGSA-N	530380	WO2022064009, Compound 155	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.31							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530380&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200310	463793860							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121286	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-14-20-15-27-26(28-21-9-12-33-13-10-21)29-24(20)17-31(18)25(32)22-8-11-30(2)16-23(22)19-6-4-3-5-7-19/h3-7,15,18,21-23H,8-14,16-17H2,1-2H3,(H,27,28,29)/t18-,22+,23-/m1/s1	XWPPDZKREULSMT-YFXJRYMSSA-N	530286	WO2022064009, Compound 156::WO2022064009, Compound 47	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.24							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530286&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200226	463793775							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121287	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C[C@@H]1c1ccccc1)C1COC1	InChI=1S/C28H37N5O3/c1-19-13-21-14-29-28(30-22-8-11-35-12-9-22)31-26(21)16-33(19)27(34)24-7-10-32(23-17-36-18-23)15-25(24)20-5-3-2-4-6-20/h2-6,14,19,22-25H,7-13,15-18H2,1H3,(H,29,30,31)/t19-,24+,25-/m1/s1	ZPOHBCBZUSSUCU-BTZRARBUSA-N	530382	WO2022064009, Compound 159	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 575							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530382&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200311	463793861							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121288	CC(C)N1CC[C@@H]([C@H](C1)c1cccc(Cl)c1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C28H38ClN5O2/c1-18(2)33-10-7-24(25(16-33)20-5-4-6-22(29)14-20)27(35)34-17-26-21(13-19(34)3)15-30-28(32-26)31-23-8-11-36-12-9-23/h4-6,14-15,18-19,23-25H,7-13,16-17H2,1-3H3,(H,30,31,32)/t19-,24+,25-/m1/s1	WIMPXFDZJSGJLR-BTZRARBUSA-N	530383	WO2022064009, Compound 160	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 110							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530383&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200312	463793862							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121289	CC(C)N1CC[C@@H]([C@H](C1)c1cccc(Cl)c1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C28H38ClN5O2/c1-18(2)33-10-7-24(25(16-33)20-5-4-6-22(29)14-20)27(35)34-17-26-21(13-19(34)3)15-30-28(32-26)31-23-8-11-36-12-9-23/h4-6,14-15,18-19,23-25H,7-13,16-17H2,1-3H3,(H,30,31,32)/t19-,24+,25-/m1/s1	WIMPXFDZJSGJLR-BTZRARBUSA-N	530383	WO2022064009, Compound 160	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.63							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530383&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200312	463793862							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121290	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C[C@@H]1c1ccccc1)C1CC1	InChI=1S/C28H37N5O2/c1-19-15-21-16-29-28(30-22-10-13-35-14-11-22)31-26(21)18-33(19)27(34)24-9-12-32(23-7-8-23)17-25(24)20-5-3-2-4-6-20/h2-6,16,19,22-25H,7-15,17-18H2,1H3,(H,29,30,31)/t19-,24+,25-/m1/s1	HBBRSBFSXUEOLJ-BTZRARBUSA-N	530384	WO2022064009, Compound 161	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 182							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530384&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200313	463793863							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121291	CC(C)N1CC[C@@H]([C@H](C1)c1ccc(Cl)c(F)c1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C28H37ClFN5O2/c1-17(2)34-9-6-22(23(15-34)19-4-5-24(29)25(30)13-19)27(36)35-16-26-20(12-18(35)3)14-31-28(33-26)32-21-7-10-37-11-8-21/h4-5,13-14,17-18,21-23H,6-12,15-16H2,1-3H3,(H,31,32,33)/t18-,22+,23-/m1/s1	KLPTVWQIHFFMLW-YFXJRYMSSA-N	530385	WO2022064009, Compound 162	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 112							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530385&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200314	463793864							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121292	CC(C)N1CC[C@@H]([C@H](C1)c1cccc(F)c1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C28H38FN5O2/c1-18(2)33-10-7-24(25(16-33)20-5-4-6-22(29)14-20)27(35)34-17-26-21(13-19(34)3)15-30-28(32-26)31-23-8-11-36-12-9-23/h4-6,14-15,18-19,23-25H,7-13,16-17H2,1-3H3,(H,30,31,32)/t19-,24+,25-/m1/s1	MTJCVEOSXBYFDI-BTZRARBUSA-N	530386	WO2022064009, Compound 163	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 148							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530386&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200315	463793865							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121293	CC(C)N1CC[C@H]([C@@H](C1)c1cccc(F)c1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C28H38FN5O2/c1-18(2)33-10-7-24(25(16-33)20-5-4-6-22(29)14-20)27(35)34-17-26-21(13-19(34)3)15-30-28(32-26)31-23-8-11-36-12-9-23/h4-6,14-15,18-19,23-25H,7-13,16-17H2,1-3H3,(H,30,31,32)/t19-,24-,25+/m1/s1	MTJCVEOSXBYFDI-WVQWTBLQSA-N	530387	WO2022064009, Compound 164	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 871							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530387&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200316	463793866							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121294	CC(C)N1CC[C@H]([C@@H](C1)c1ccc(Cl)c(F)c1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C28H37ClFN5O2/c1-17(2)34-9-6-22(23(15-34)19-4-5-24(29)25(30)13-19)27(36)35-16-26-20(12-18(35)3)14-31-28(33-26)32-21-7-10-37-11-8-21/h4-5,13-14,17-18,21-23H,6-12,15-16H2,1-3H3,(H,31,32,33)/t18-,22-,23+/m1/s1	KLPTVWQIHFFMLW-YSZBQJHXSA-N	530388	WO2022064009, Compound 165	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 794							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530388&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200317	463793867							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121295	CC(C)N1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C29H41N5O2/c1-19(2)33-11-8-25(26(17-33)22-7-5-6-20(3)14-22)28(35)34-18-27-23(15-21(34)4)16-30-29(32-27)31-24-9-12-36-13-10-24/h5-7,14,16,19,21,24-26H,8-13,15,17-18H2,1-4H3,(H,30,31,32)/t21-,25+,26-/m1/s1	SSWFQDJSFVACPN-QGUKFAFCSA-N	530389	WO2022064009, Compound 166	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 18							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530389&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200318	463793868							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121296	CC(C)N1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C29H41N5O2/c1-19(2)33-11-8-25(26(17-33)22-7-5-6-20(3)14-22)28(35)34-18-27-23(15-21(34)4)16-30-29(32-27)31-24-9-12-36-13-10-24/h5-7,14,16,19,21,24-26H,8-13,15,17-18H2,1-4H3,(H,30,31,32)/t21-,25+,26-/m1/s1	SSWFQDJSFVACPN-QGUKFAFCSA-N	530389	WO2022064009, Compound 166	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 14							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530389&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200318	463793868							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121297	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CC[C@H](CN1c1ccccc1)N(C)C	InChI=1S/C27H38N6O2/c1-19-15-20-16-28-27(29-21-11-13-35-14-12-21)30-24(20)18-32(19)26(34)25-10-9-23(31(2)3)17-33(25)22-7-5-4-6-8-22/h4-8,16,19,21,23,25H,9-15,17-18H2,1-3H3,(H,28,29,30)/t19-,23-,25+/m1/s1	YOGVGMGAMUCIKV-NIDLKEISSA-N	530390	WO2022064009, Compound 167	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 562							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530390&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200319	463793869							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121298	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CC[C@H](CN1c1ccccc1)N(C)C	InChI=1S/C27H38N6O2/c1-19-15-20-16-28-27(29-21-11-13-35-14-12-21)30-24(20)18-32(19)26(34)25-10-9-23(31(2)3)17-33(25)22-7-5-4-6-8-22/h4-8,16,19,21,23,25H,9-15,17-18H2,1-3H3,(H,28,29,30)/t19-,23-,25+/m1/s1	YOGVGMGAMUCIKV-NIDLKEISSA-N	530390	WO2022064009, Compound 167	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 112							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530390&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200319	463793869							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121299	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@@H]1CC[C@@H](CN1c1ccccc1)N(C)C	InChI=1S/C27H38N6O2/c1-19-15-20-16-28-27(29-21-11-13-35-14-12-21)30-24(20)18-32(19)26(34)25-10-9-23(31(2)3)17-33(25)22-7-5-4-6-8-22/h4-8,16,19,21,23,25H,9-15,17-18H2,1-3H3,(H,28,29,30)/t19-,23+,25+/m1/s1	YOGVGMGAMUCIKV-VPHKFGTKSA-N	530391	WO2022064009, Compound 168	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1349							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530391&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200320	463793870							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121300	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H33N5O2/c1-17-12-19-13-26-25(27-20-8-10-32-11-9-20)28-23(19)16-30(17)24(31)22-15-29(2)14-21(22)18-6-4-3-5-7-18/h3-7,13,17,20-22H,8-12,14-16H2,1-2H3,(H,26,27,28)/t17-,21-,22+/m1/s1	URSYPXIFYVLKOA-YHYVQYDKSA-N	530392	WO2022064009, Compound 169a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 468							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530392&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200321	463793871							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121301	C[C@@H]1C[C@@H]([C@H](CN1C)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C27H37N5O2/c1-18-14-23(24(16-31(18)3)20-7-5-4-6-8-20)26(33)32-17-25-21(13-19(32)2)15-28-27(30-25)29-22-9-11-34-12-10-22/h4-8,15,18-19,22-24H,9-14,16-17H2,1-3H3,(H,28,29,30)/t18-,19-,23+,24-/m1/s1	CMFDUWMVZFRLRC-PBIIQAGSSA-N	530393	WO2022064009, Compound 170a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 794							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530393&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200322	463793872							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121302	C[C@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-14-20-15-27-26(28-21-9-12-33-13-10-21)29-24(20)17-31(18)25(32)22-8-11-30(2)16-23(22)19-6-4-3-5-7-19/h3-7,15,18,21-23H,8-14,16-17H2,1-2H3,(H,27,28,29)/t18-,22-,23+/m0/s1	XWPPDZKREULSMT-OFAXGOBFSA-N	530394	WO2022064009, Compound 171a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530394&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200323	463793873							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121303	C[C@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-14-20-15-27-26(28-21-9-12-33-13-10-21)29-24(20)17-31(18)25(32)22-8-11-30(2)16-23(22)19-6-4-3-5-7-19/h3-7,15,18,21-23H,8-14,16-17H2,1-2H3,(H,27,28,29)/t18-,22-,23+/m0/s1	XWPPDZKREULSMT-OFAXGOBFSA-N	530394	WO2022064009, Compound 171a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5.75							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530394&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200323	463793873							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121304	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O2/c1-19-15-21-16-29-28(30-22-9-11-23(35-3)12-10-22)31-26(21)18-33(19)27(34)24-13-14-32(2)17-25(24)20-7-5-4-6-8-20/h4-8,16,19,22-25H,9-15,17-18H2,1-3H3,(H,29,30,31)/t19-,22-,23-,24-,25+/m0/s1	TXYGAIXPPILEQF-FUBBUTDDSA-N	530395	WO2022064009, Compound 172	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<10.00							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530395&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200324	463793874							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121305	CO[C@H]1CC[C@@H](CC1)Nc1ncc2C[C@H](C)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N5O2/c1-19-15-21-16-29-28(30-22-9-11-23(35-3)12-10-22)31-26(21)18-33(19)27(34)24-13-14-32(2)17-25(24)20-7-5-4-6-8-20/h4-8,16,19,22-25H,9-15,17-18H2,1-3H3,(H,29,30,31)/t19-,22-,23-,24-,25+/m0/s1	TXYGAIXPPILEQF-FUBBUTDDSA-N	530395	WO2022064009, Compound 172	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 7.41							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530395&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200324	463793874							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121306	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=N)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H34N6/c1-20-15-23-17-31-28(30-16-21-9-5-3-6-10-21)32-26(23)19-34(20)27(29)24-13-14-33(2)18-25(24)22-11-7-4-8-12-22/h3-12,17,20,24-25,29H,13-16,18-19H2,1-2H3,(H,30,31,32)/t20-,24+,25-/m1/s1	UZIRRMVUNZXLKX-DCEDVJGZSA-N	530396	WO2022064009, Compound 173	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<10.00							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530396&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200325	463793875							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121307	C[C@@H]1Cc2cnc(NCc3ccccc3)nc2CN1C(=N)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H34N6/c1-20-15-23-17-31-28(30-16-21-9-5-3-6-10-21)32-26(23)19-34(20)27(29)24-13-14-33(2)18-25(24)22-11-7-4-8-12-22/h3-12,17,20,24-25,29H,13-16,18-19H2,1-2H3,(H,30,31,32)/t20-,24+,25-/m1/s1	UZIRRMVUNZXLKX-DCEDVJGZSA-N	530396	WO2022064009, Compound 173	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1.66							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530396&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200325	463793875							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121308	C[C@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H33N7O/c1-18-13-20-14-27-26(28-15-21-9-12-32(3)30-21)29-24(20)17-33(18)25(34)22-10-11-31(2)16-23(22)19-7-5-4-6-8-19/h4-9,12,14,18,22-23H,10-11,13,15-17H2,1-3H3,(H,27,28,29)/t18-,22-,23+/m0/s1	KLUZOYLPHBNTLS-OFAXGOBFSA-N	530397	WO2022064009, Compound 174	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 11							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530397&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200326	463793876							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121309	C[C@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H33N7O/c1-18-13-20-14-27-26(28-15-21-9-12-32(3)30-21)29-24(20)17-33(18)25(34)22-10-11-31(2)16-23(22)19-7-5-4-6-8-19/h4-9,12,14,18,22-23H,10-11,13,15-17H2,1-3H3,(H,27,28,29)/t18-,22-,23+/m0/s1	KLUZOYLPHBNTLS-OFAXGOBFSA-N	530397	WO2022064009, Compound 174	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.63							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530397&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200326	463793876							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121310	CC[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-3-22-15-20-16-28-27(29-21-10-13-34-14-11-21)30-25(20)18-32(22)26(33)23-9-12-31(2)17-24(23)19-7-5-4-6-8-19/h4-8,16,21-24H,3,9-15,17-18H2,1-2H3,(H,28,29,30)/t22-,23+,24-/m1/s1	CKOZXDNMZKMXRB-TZRRMPRUSA-N	530398	WO2022064009, Compound 185	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 43							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530398&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200327	463793877							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121311	CC[C@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-3-22-15-20-16-28-27(29-21-10-13-34-14-11-21)30-25(20)18-32(22)26(33)23-9-12-31(2)17-24(23)19-7-5-4-6-8-19/h4-8,16,21-24H,3,9-15,17-18H2,1-2H3,(H,28,29,30)/t22-,23-,24+/m0/s1	CKOZXDNMZKMXRB-KMDXXIMOSA-N	530399	WO2022064009, Compound 186	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530399&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200328	463793878							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121312	C[C@H]1CN(Cc2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-15-31(17-24-22(18)14-27-26(29-24)28-20-9-12-33-13-10-20)25(32)21-8-11-30(2)16-23(21)19-6-4-3-5-7-19/h3-7,14,18,20-21,23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,21-,23+/m0/s1	YADMVBDEAXRJCI-AVCGJXAMSA-N	530400	WO2022064009, Compound 187	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530400&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200329	463793879							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121313	C[C@@H]1CN(Cc2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-15-31(17-24-22(18)14-27-26(29-24)28-20-9-12-33-13-10-20)25(32)21-8-11-30(2)16-23(21)19-6-4-3-5-7-19/h3-7,14,18,20-21,23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,21+,23-/m1/s1	YADMVBDEAXRJCI-RZFNWQHOSA-N	530401	WO2022064009, Compound 188	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530401&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200330	463793880							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121314	C[C@@H]1CN(Cc2nc(NC3CCOCC3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H35N5O2/c1-18-15-31(17-24-22(18)14-27-26(29-24)28-20-9-12-33-13-10-20)25(32)21-8-11-30(2)16-23(21)19-6-4-3-5-7-19/h3-7,14,18,20-21,23H,8-13,15-17H2,1-2H3,(H,27,28,29)/t18-,21+,23-/m1/s1	YADMVBDEAXRJCI-RZFNWQHOSA-N	530401	WO2022064009, Compound 188	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2.82							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530401&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200330	463793880							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121315	CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2CC1(C)C	InChI=1S/C27H37N5O2/c1-27(2)15-20-16-28-26(29-21-10-13-34-14-11-21)30-24(20)18-32(27)25(33)22-9-12-31(3)17-23(22)19-7-5-4-6-8-19/h4-8,16,21-23H,9-15,17-18H2,1-3H3,(H,28,29,30)/t22-,23+/m0/s1	ICIQSJDHHCNQBS-XZOQPEGZSA-N	530402	WO2022064009, Compound 189	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 18							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530402&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200331	463793881							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121316	CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2CC1(C)C	InChI=1S/C27H37N5O2/c1-27(2)15-20-16-28-26(29-21-10-13-34-14-11-21)30-24(20)18-32(27)25(33)22-9-12-31(3)17-23(22)19-7-5-4-6-8-19/h4-8,16,21-23H,9-15,17-18H2,1-3H3,(H,28,29,30)/t22-,23+/m0/s1	ICIQSJDHHCNQBS-XZOQPEGZSA-N	530402	WO2022064009, Compound 189	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 22							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530402&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200331	463793881							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121317	CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NCc3ccn(C)n3)ncc2CC1(C)C	InChI=1S/C27H35N7O/c1-27(2)14-20-15-28-26(29-16-21-10-13-33(4)31-21)30-24(20)18-34(27)25(35)22-11-12-32(3)17-23(22)19-8-6-5-7-9-19/h5-10,13,15,22-23H,11-12,14,16-18H2,1-4H3,(H,28,29,30)/t22-,23+/m0/s1	REHMSTUJKAANPO-XZOQPEGZSA-N	530403	WO2022064009, Compound 191	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 295							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530403&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200332	463793882							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121318	CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NCc3ccn(C)n3)ncc2CC1(C)C	InChI=1S/C27H35N7O/c1-27(2)14-20-15-28-26(29-16-21-10-13-33(4)31-21)30-24(20)18-34(27)25(35)22-11-12-32(3)17-23(22)19-8-6-5-7-9-19/h5-10,13,15,22-23H,11-12,14,16-18H2,1-4H3,(H,28,29,30)/t22-,23+/m0/s1	REHMSTUJKAANPO-XZOQPEGZSA-N	530403	WO2022064009, Compound 191	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 39							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530403&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200332	463793882							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121319	CO[C@H]1CC[C@@H](CC1)Nc1ncc2CC3(CC3)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H39N5O2/c1-33-15-12-24(25(18-33)20-6-4-3-5-7-20)27(35)34-19-26-21(16-29(34)13-14-29)17-30-28(32-26)31-22-8-10-23(36-2)11-9-22/h3-7,17,22-25H,8-16,18-19H2,1-2H3,(H,30,31,32)/t22-,23-,24-,25+/m0/s1	YMHSMVVOGVDKAR-OJJQZRKESA-N	530404	WO2022064009, Compound 192	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 158							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530404&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200333	463793883							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121320	CO[C@H]1CC[C@@H](CC1)Nc1ncc2CC3(CC3)N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C29H39N5O2/c1-33-15-12-24(25(18-33)20-6-4-3-5-7-20)27(35)34-19-26-21(16-29(34)13-14-29)17-30-28(32-26)31-22-8-10-23(36-2)11-9-22/h3-7,17,22-25H,8-16,18-19H2,1-2H3,(H,30,31,32)/t22-,23-,24-,25+/m0/s1	YMHSMVVOGVDKAR-OJJQZRKESA-N	530404	WO2022064009, Compound 192	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 145							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530404&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200333	463793883							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121321	CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C(C)(C)C1	InChI=1S/C27H37N5O2/c1-27(2)18-32(17-24-23(27)15-28-26(30-24)29-20-10-13-34-14-11-20)25(33)21-9-12-31(3)16-22(21)19-7-5-4-6-8-19/h4-8,15,20-22H,9-14,16-18H2,1-3H3,(H,28,29,30)/t21-,22+/m0/s1	WURFXILWRMLZCB-FCHUYYIVSA-N	530405	WO2022064009, Compound 193	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 178							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530405&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200334	463793884							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121322	CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C(C)(C)C1	InChI=1S/C27H37N5O2/c1-27(2)18-32(17-24-23(27)15-28-26(30-24)29-20-10-13-34-14-11-20)25(33)21-9-12-31(3)16-22(21)19-7-5-4-6-8-19/h4-8,15,20-22H,9-14,16-18H2,1-3H3,(H,28,29,30)/t21-,22+/m0/s1	WURFXILWRMLZCB-FCHUYYIVSA-N	530405	WO2022064009, Compound 193	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 89							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530405&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200334	463793884							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121323	CC1CN(Cc2nc(Nc3cnn(C)c3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H31N7O/c1-17-13-32(16-23-21(17)12-26-25(29-23)28-19-11-27-31(3)14-19)24(33)20-9-10-30(2)15-22(20)18-7-5-4-6-8-18/h4-8,11-12,14,17,20,22H,9-10,13,15-16H2,1-3H3,(H,26,28,29)/t17?,20-,22+/m0/s1	ZSYQCLGRKYBQHY-LNMRYCPJSA-N	530406	WO2022064009, Compound 194	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 18							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530406&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200335	463793885							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121324	CC1CN(Cc2nc(Nc3cnn(C)c3)ncc12)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H31N7O/c1-17-13-32(16-23-21(17)12-26-25(29-23)28-19-11-27-31(3)14-19)24(33)20-9-10-30(2)15-22(20)18-7-5-4-6-8-18/h4-8,11-12,14,17,20,22H,9-10,13,15-16H2,1-3H3,(H,26,28,29)/t17?,20-,22+/m0/s1	ZSYQCLGRKYBQHY-LNMRYCPJSA-N	530406	WO2022064009, Compound 194	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.17							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530406&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200335	463793885							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121325	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2[C@@H](C)N1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-15-21-16-28-27(29-22-10-13-34-14-11-22)30-25(21)19(2)32(18)26(33)23-9-12-31(3)17-24(23)20-7-5-4-6-8-20/h4-8,16,18-19,22-24H,9-15,17H2,1-3H3,(H,28,29,30)/t18-,19-,23+,24-/m1/s1	BZHLKNWXJVAFNQ-PBIIQAGSSA-N	530407	WO2022064009, Compound 195a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 4677							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530407&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200336	463793886							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121326	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2[C@H](C)N1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-15-21-16-28-27(29-22-10-13-34-14-11-22)30-25(21)19(2)32(18)26(33)23-9-12-31(3)17-24(23)20-7-5-4-6-8-20/h4-8,16,18-19,22-24H,9-15,17H2,1-3H3,(H,28,29,30)/t18-,19+,23+,24-/m1/s1	BZHLKNWXJVAFNQ-RJADORODSA-N	530408	WO2022064009, Compound 195b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530408&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200337	463793887							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121327	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2[C@H](C)N1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H37N5O2/c1-18-15-21-16-28-27(29-22-10-13-34-14-11-22)30-25(21)19(2)32(18)26(33)23-9-12-31(3)17-24(23)20-7-5-4-6-8-20/h4-8,16,18-19,22-24H,9-15,17H2,1-3H3,(H,28,29,30)/t18-,19+,23+,24-/m1/s1	BZHLKNWXJVAFNQ-RJADORODSA-N	530408	WO2022064009, Compound 195b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 4.90							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530408&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200337	463793887							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121328	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2[C@@H](C)N1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H35N7O/c1-18-14-21-15-28-27(29-16-22-10-13-33(4)31-22)30-25(21)19(2)34(18)26(35)23-11-12-32(3)17-24(23)20-8-6-5-7-9-20/h5-10,13,15,18-19,23-24H,11-12,14,16-17H2,1-4H3,(H,28,29,30)/t18-,19-,23+,24-/m1/s1	OGQIZEPQWHRIGN-PBIIQAGSSA-N	530409	WO2022064009, Compound 197	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 776							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530409&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200338	463793888							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121329	CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2[C@@H]2C[C@H]12	InChI=1S/C26H33N5O2/c1-30-10-7-19(22(15-30)17-5-3-2-4-6-17)25(32)31-16-23-21(20-13-24(20)31)14-27-26(29-23)28-18-8-11-33-12-9-18/h2-6,14,18-20,22,24H,7-13,15-16H2,1H3,(H,27,28,29)/t19-,20-,22+,24-/m0/s1	FFOCQCBKTFPCLX-QRVLJTFESA-N	530410	WO2022064009, Compound 199	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<9.77							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530410&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200339	463793889							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121330	CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2[C@@H]2C[C@H]12	InChI=1S/C26H33N5O2/c1-30-10-7-19(22(15-30)17-5-3-2-4-6-17)25(32)31-16-23-21(20-13-24(20)31)14-27-26(29-23)28-18-8-11-33-12-9-18/h2-6,14,18-20,22,24H,7-13,15-16H2,1H3,(H,27,28,29)/t19-,20-,22+,24-/m0/s1	FFOCQCBKTFPCLX-QRVLJTFESA-N	530410	WO2022064009, Compound 199	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5.37							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530410&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200339	463793889							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121331	CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(Nc3cnn(C)c3)ncc2[C@@H]2C[C@H]12	InChI=1S/C25H29N7O/c1-30-9-8-18(21(14-30)16-6-4-3-5-7-16)24(33)32-15-22-20(19-10-23(19)32)12-26-25(29-22)28-17-11-27-31(2)13-17/h3-7,11-13,18-19,21,23H,8-10,14-15H2,1-2H3,(H,26,28,29)/t18-,19-,21+,23-/m0/s1	JPOYQQRJNPZXTP-VKUXKFIQSA-N	530411	WO2022064009, Compound 200	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 35							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530411&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200340	463793890							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121332	CN1CC[C@@H]([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(Nc3cnn(C)c3)ncc2[C@@H]2C[C@H]12	InChI=1S/C25H29N7O/c1-30-9-8-18(21(14-30)16-6-4-3-5-7-16)24(33)32-15-22-20(19-10-23(19)32)12-26-25(29-22)28-17-11-27-31(2)13-17/h3-7,11-13,18-19,21,23H,8-10,14-15H2,1-2H3,(H,26,28,29)/t18-,19-,21+,23-/m0/s1	JPOYQQRJNPZXTP-VKUXKFIQSA-N	530411	WO2022064009, Compound 200	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 17							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530411&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200340	463793890							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121333	CO[C@H]1CC[C@@H](CC1)Nc1ncc2[C@@H]3C[C@@H]3N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H37N5O2/c1-32-13-12-21(24(16-32)18-6-4-3-5-7-18)27(34)33-17-25-23(22-14-26(22)33)15-29-28(31-25)30-19-8-10-20(35-2)11-9-19/h3-7,15,19-22,24,26H,8-14,16-17H2,1-2H3,(H,29,30,31)/t19-,20-,21-,22-,24+,26-/m0/s1	NWQXULCLHZFMAJ-KNCNJFNZSA-N	530412	WO2022064009, Compound 201	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 33							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530412&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200341	463793891							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121334	CO[C@H]1CC[C@@H](CC1)Nc1ncc2[C@@H]3C[C@@H]3N(Cc2n1)C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H37N5O2/c1-32-13-12-21(24(16-32)18-6-4-3-5-7-18)27(34)33-17-25-23(22-14-26(22)33)15-29-28(31-25)30-19-8-10-20(35-2)11-9-19/h3-7,15,19-22,24,26H,8-14,16-17H2,1-2H3,(H,29,30,31)/t19-,20-,21-,22-,24+,26-/m0/s1	NWQXULCLHZFMAJ-KNCNJFNZSA-N	530412	WO2022064009, Compound 201	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.92							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530412&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200341	463793891							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121335	CN1CC[C@H]([C@@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(Nc3cnn(C)c3)ncc2[C@@H]2C[C@H]12	InChI=1S/C26H31N7O/c1-16-5-4-6-17(9-16)22-14-31(2)8-7-19(22)25(34)33-15-23-21(20-10-24(20)33)12-27-26(30-23)29-18-11-28-32(3)13-18/h4-6,9,11-13,19-20,22,24H,7-8,10,14-15H2,1-3H3,(H,27,29,30)/t19-,20+,22+,24+/m1/s1	MJGXMKHXJHQKDV-RDCABSMISA-N	530413	WO2022064009, Compound 202	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2344							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530413&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200342	463793892							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121336	CN1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(Nc3cnn(C)c3)ncc2[C@@H]2C[C@H]12	InChI=1S/C26H31N7O/c1-16-5-4-6-17(9-16)22-14-31(2)8-7-19(22)25(34)33-15-23-21(20-10-24(20)33)12-27-26(30-23)29-18-11-28-32(3)13-18/h4-6,9,11-13,19-20,22,24H,7-8,10,14-15H2,1-3H3,(H,27,29,30)/t19-,20-,22+,24-/m0/s1	MJGXMKHXJHQKDV-QRVLJTFESA-N	530414	WO2022064009, Compound 203	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 17							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530414&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200343	463793893							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121337	CN1CC[C@@H]([C@H](C1)c1cccc(C)c1)C(=O)N1Cc2nc(Nc3cnn(C)c3)ncc2[C@@H]2C[C@H]12	InChI=1S/C26H31N7O/c1-16-5-4-6-17(9-16)22-14-31(2)8-7-19(22)25(34)33-15-23-21(20-10-24(20)33)12-27-26(30-23)29-18-11-28-32(3)13-18/h4-6,9,11-13,19-20,22,24H,7-8,10,14-15H2,1-3H3,(H,27,29,30)/t19-,20-,22+,24-/m0/s1	MJGXMKHXJHQKDV-QRVLJTFESA-N	530414	WO2022064009, Compound 203	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5.37							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530414&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200343	463793893							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121338	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H34N6O2/c1-18-14-20-15-26-24(27-21-8-12-33-13-9-21)28-22(20)16-31(18)25(32)30-11-10-29(2)17-23(30)19-6-4-3-5-7-19/h3-7,15,18,21,23H,8-14,16-17H2,1-2H3,(H,26,27,28)/t18-,23-/m1/s1	VCDXKVSUQVNUPB-WZONZLPQSA-N	530415	WO2022064009, Compound 204a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 15							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530415&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200344	463793894							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121339	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H34N6O2/c1-18-14-20-15-26-24(27-21-8-12-33-13-9-21)28-22(20)16-31(18)25(32)30-11-10-29(2)17-23(30)19-6-4-3-5-7-19/h3-7,15,18,21,23H,8-14,16-17H2,1-2H3,(H,26,27,28)/t18-,23-/m1/s1	VCDXKVSUQVNUPB-WZONZLPQSA-N	530415	WO2022064009, Compound 204a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.76							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530415&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200344	463793894							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121340	CN1CCN([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2CC1(C)C	InChI=1S/C26H36N6O2/c1-26(2)15-20-16-27-24(28-21-9-13-34-14-10-21)29-22(20)17-32(26)25(33)31-12-11-30(3)18-23(31)19-7-5-4-6-8-19/h4-8,16,21,23H,9-15,17-18H2,1-3H3,(H,27,28,29)/t23-/m1/s1	FOBMBELMBHICIM-HSZRJFAPSA-N	530416	WO2022064009, Compound 205	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 13							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530416&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200345	463793895							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121341	CC(C)N1CCN([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C27H38N6O2/c1-19(2)31-11-12-32(25(18-31)21-7-5-4-6-8-21)27(34)33-17-24-22(15-20(33)3)16-28-26(30-24)29-23-9-13-35-14-10-23/h4-8,16,19-20,23,25H,9-15,17-18H2,1-3H3,(H,28,29,30)/t20-,25-/m1/s1	OTQKMFXZFVQNPD-CJFMBICVSA-N	530417	WO2022064009, Compound 206	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 16							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530417&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200346	463793896							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121342	CC(C)N1CCN([C@H](C1)c1ccccc1)C(=O)N1Cc2nc(NC3CCOCC3)ncc2C[C@H]1C	InChI=1S/C27H38N6O2/c1-19(2)31-11-12-32(25(18-31)21-7-5-4-6-8-21)27(34)33-17-24-22(15-20(33)3)16-28-26(30-24)29-23-9-13-35-14-10-23/h4-8,16,19-20,23,25H,9-15,17-18H2,1-3H3,(H,28,29,30)/t20-,25-/m1/s1	OTQKMFXZFVQNPD-CJFMBICVSA-N	530417	WO2022064009, Compound 206	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 6.46							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530417&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200346	463793896							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121343	C[C@H]1Cc2cnc(NC3(COC3)c3ccccc3)cc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C31H36N4O2/c1-22-15-24-17-32-29(33-31(20-37-21-31)26-11-7-4-8-12-26)16-25(24)18-35(22)30(36)27-13-14-34(2)19-28(27)23-9-5-3-6-10-23/h3-12,16-17,22,27-28H,13-15,18-21H2,1-2H3,(H,32,33)/t22-,27-,28+/m0/s1	SBXUVFLJUOJULC-QLCOJLISSA-N	530418	WO2022064009, Compound 175	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 30							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530418&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200347	463793897							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121344	C[C@H]1Cc2cnc(NC3(COC3)c3ccccc3)cc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C31H36N4O2/c1-22-15-24-17-32-29(33-31(20-37-21-31)26-11-7-4-8-12-26)16-25(24)18-35(22)30(36)27-13-14-34(2)19-28(27)23-9-5-3-6-10-23/h3-12,16-17,22,27-28H,13-15,18-21H2,1-2H3,(H,32,33)/t22-,27-,28+/m0/s1	SBXUVFLJUOJULC-QLCOJLISSA-N	530418	WO2022064009, Compound 175	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 7.41							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530418&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200347	463793897							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121345	C[C@H]1Cc2cnc(Nc3cnn(C)c3)cc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H32N6O/c1-18-11-20-13-27-25(29-22-14-28-31(3)16-22)12-21(20)15-32(18)26(33)23-9-10-30(2)17-24(23)19-7-5-4-6-8-19/h4-8,12-14,16,18,23-24H,9-11,15,17H2,1-3H3,(H,27,29)/t18-,23-,24+/m0/s1	ZSPKGLQDWCDKNG-GKVQRAMASA-N	530419	WO2022064009, Compound 176	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 23							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530419&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200348	463793898							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121346	C[C@H]1Cc2cnc(Nc3cnn(C)c3)cc2CN1C(=O)[C@H]1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H32N6O/c1-18-11-20-13-27-25(29-22-14-28-31(3)16-22)12-21(20)15-32(18)26(33)23-9-10-30(2)17-24(23)19-7-5-4-6-8-19/h4-8,12-14,16,18,23-24H,9-11,15,17H2,1-3H3,(H,27,29)/t18-,23-,24+/m0/s1	ZSPKGLQDWCDKNG-GKVQRAMASA-N	530419	WO2022064009, Compound 176	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 9.12							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530419&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200348	463793898							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121347	CO[C@H]1CC[C@@H](CC1)Nc1cc2CN([C@@H](C)Cc2cn1)C(=O)C1CCN(C)CC1c1cccc(C)c1	InChI=1S/C30H42N4O2/c1-20-6-5-7-22(14-20)28-19-33(3)13-12-27(28)30(35)34-18-24-16-29(31-17-23(24)15-21(34)2)32-25-8-10-26(36-4)11-9-25/h5-7,14,16-17,21,25-28H,8-13,15,18-19H2,1-4H3,(H,31,32)/t21-,25-,26-,27?,28?/m0/s1	VYPXLUSXPNXRRO-FSSQJUNMSA-N	530420	WO2022064009, Compound 177a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 29							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530420&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200349	463793899							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121348	CO[C@H]1CC[C@@H](CC1)Nc1cc2CN([C@@H](C)Cc2cn1)C(=O)C1CCN(C)CC1c1cccc(C)c1	InChI=1S/C30H42N4O2/c1-20-6-5-7-22(14-20)28-19-33(3)13-12-27(28)30(35)34-18-24-16-29(31-17-23(24)15-21(34)2)32-25-8-10-26(36-4)11-9-25/h5-7,14,16-17,21,25-28H,8-13,15,18-19H2,1-4H3,(H,31,32)/t21-,25-,26-,27?,28?/m0/s1	VYPXLUSXPNXRRO-FSSQJUNMSA-N	530420	WO2022064009, Compound 177a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 12							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530420&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200349	463793899							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121349	CO[C@H]1CC[C@@H](CC1)Nc1cc2CN([C@@H](C)Cc2cn1)C(=O)[C@@H]1CCN(C)C[C@H]1c1cccc(C)c1	InChI=1S/C30H42N4O2/c1-20-6-5-7-22(14-20)28-19-33(3)13-12-27(28)30(35)34-18-24-16-29(31-17-23(24)15-21(34)2)32-25-8-10-26(36-4)11-9-25/h5-7,14,16-17,21,25-28H,8-13,15,18-19H2,1-4H3,(H,31,32)/t21-,25-,26-,27+,28-/m0/s1	VYPXLUSXPNXRRO-BKNMONHFSA-N	530421	WO2022064009, Compound 177b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530421&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200350	463793900							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121350	C[C@@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)N1CCNC[C@@H]1c1ccccc1	InChI=1S/C24H32N6O2/c1-17-13-19-14-26-23(27-20-7-11-32-12-8-20)28-21(19)16-30(17)24(31)29-10-9-25-15-22(29)18-5-3-2-4-6-18/h2-6,14,17,20,22,25H,7-13,15-16H2,1H3,(H,26,27,28)/t17-,22-/m1/s1	AOPULEPXSRWMEU-VGOFRKELSA-N	530422	WO2022064009, Compound 208	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 22							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530422&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200351	463793901							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121351	C[C@@H]1Cc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H37N7O3S/c1-19-15-21-16-27-25(28-22-9-11-31(12-10-22)37(3,35)36)29-23(21)17-33(19)26(34)32-14-13-30(2)18-24(32)20-7-5-4-6-8-20/h4-8,16,19,22,24H,9-15,17-18H2,1-3H3,(H,27,28,29)/t19-,24-/m1/s1	SNWVMKZGGAITBS-NTKDMRAZSA-N	530423	WO2022064009, Compound 209	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 17							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530423&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200352	463793902							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121352	C[C@@H]1Cc2cnc(NC3CCN(CC3)S(C)(=O)=O)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C26H37N7O3S/c1-19-15-21-16-27-25(28-22-9-11-31(12-10-22)37(3,35)36)29-23(21)17-33(19)26(34)32-14-13-30(2)18-24(32)20-7-5-4-6-8-20/h4-8,16,19,22,24H,9-15,17-18H2,1-3H3,(H,27,28,29)/t19-,24-/m1/s1	SNWVMKZGGAITBS-NTKDMRAZSA-N	530423	WO2022064009, Compound 209	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.31							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530423&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200352	463793902							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121353	C[C@@H]1Cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N7O3S/c1-20-16-22-17-29-27(30-23-10-12-33(13-11-23)39(37,38)24-8-9-24)31-25(22)18-35(20)28(36)34-15-14-32(2)19-26(34)21-6-4-3-5-7-21/h3-7,17,20,23-24,26H,8-16,18-19H2,1-2H3,(H,29,30,31)/t20-,26-/m1/s1	KGUMFAWGZPNUEW-FQRUVTKNSA-N	530424	WO2022064009, Compound 210	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<20							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530424&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200353	463793903							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121354	C[C@@H]1Cc2cnc(NC3CCN(CC3)S(=O)(=O)C3CC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C28H39N7O3S/c1-20-16-22-17-29-27(30-23-10-12-33(13-11-23)39(37,38)24-8-9-24)31-25(22)18-35(20)28(36)34-15-14-32(2)19-26(34)21-6-4-3-5-7-21/h3-7,17,20,23-24,26H,8-16,18-19H2,1-2H3,(H,29,30,31)/t20-,26-/m1/s1	KGUMFAWGZPNUEW-FQRUVTKNSA-N	530424	WO2022064009, Compound 210	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 3.31							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530424&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200353	463793903							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121355	C[C@@H]1Cc2cnc(NC3CCN(CC3)S(=O)(=O)N(C)C)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H40N8O3S/c1-20-16-22-17-28-26(29-23-10-12-33(13-11-23)39(37,38)31(2)3)30-24(22)18-35(20)27(36)34-15-14-32(4)19-25(34)21-8-6-5-7-9-21/h5-9,17,20,23,25H,10-16,18-19H2,1-4H3,(H,28,29,30)/t20-,25-/m1/s1	SEGFKKZKDIJBSY-CJFMBICVSA-N	530425	WO2022064009, Compound 211	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<20							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530425&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200354	463793904							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121356	C[C@@H]1Cc2cnc(NC3CCN(CC3)S(=O)(=O)N(C)C)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C27H40N8O3S/c1-20-16-22-17-28-26(29-23-10-12-33(13-11-23)39(37,38)31(2)3)30-24(22)18-35(20)27(36)34-15-14-32(4)19-25(34)21-8-6-5-7-9-21/h5-9,17,20,23,25H,10-16,18-19H2,1-4H3,(H,28,29,30)/t20-,25-/m1/s1	SEGFKKZKDIJBSY-CJFMBICVSA-N	530425	WO2022064009, Compound 211	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 13							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530425&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200354	463793904							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121357	C[C@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)N1CCN(C)C[C@H]1c1cccc(F)c1	InChI=1S/C25H33FN6O2/c1-17-12-19-14-27-24(28-21-6-10-34-11-7-21)29-22(19)15-32(17)25(33)31-9-8-30(2)16-23(31)18-4-3-5-20(26)13-18/h3-5,13-14,17,21,23H,6-12,15-16H2,1-2H3,(H,27,28,29)/t17-,23-/m0/s1	BLLZHXZECKWOMV-SBUREZEXSA-N	530426	WO2022064009, Compound 212	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 13							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530426&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200355	463793905							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121358	C[C@H]1Cc2cnc(NC3CCOCC3)nc2CN1C(=O)N1CCN(C)C[C@H]1c1cccc(F)c1	InChI=1S/C25H33FN6O2/c1-17-12-19-14-27-24(28-21-6-10-34-11-7-21)29-22(19)15-32(17)25(33)31-9-8-30(2)16-23(31)18-4-3-5-20(26)13-18/h3-5,13-14,17,21,23H,6-12,15-16H2,1-2H3,(H,27,28,29)/t17-,23-/m0/s1	BLLZHXZECKWOMV-SBUREZEXSA-N	530426	WO2022064009, Compound 212	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 4.79							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530426&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200355	463793905							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121359	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H32N8O/c1-18-13-20-14-26-24(27-15-21-9-10-31(3)29-21)28-22(20)16-33(18)25(34)32-12-11-30(2)17-23(32)19-7-5-4-6-8-19/h4-10,14,18,23H,11-13,15-17H2,1-3H3,(H,26,27,28)/t18-,23-/m1/s1	PAMKRBCAEQZZRE-WZONZLPQSA-N	530427	WO2022064009, Compound 213	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 158							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530427&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200356	463793906							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121360	C[C@@H]1Cc2cnc(NCc3ccn(C)n3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H32N8O/c1-18-13-20-14-26-24(27-15-21-9-10-31(3)29-21)28-22(20)16-33(18)25(34)32-12-11-30(2)17-23(32)19-7-5-4-6-8-19/h4-10,14,18,23H,11-13,15-17H2,1-3H3,(H,26,27,28)/t18-,23-/m1/s1	PAMKRBCAEQZZRE-WZONZLPQSA-N	530427	WO2022064009, Compound 213	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 126							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530427&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200356	463793906							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121361	C[C@@H]1Cc2cnc(NC3CCS(=O)(=O)CC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H34N6O3S/c1-18-14-20-15-26-24(27-21-8-12-35(33,34)13-9-21)28-22(20)16-31(18)25(32)30-11-10-29(2)17-23(30)19-6-4-3-5-7-19/h3-7,15,18,21,23H,8-14,16-17H2,1-2H3,(H,26,27,28)/t18-,23-/m1/s1	VINIZKSQBWUQIG-WZONZLPQSA-N	530428	WO2022064009, Compound 214	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 28							WIPO		10.7270/Q2MC936B		aid1806200	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530428&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200357	463793907							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1121362	C[C@@H]1Cc2cnc(NC3CCS(=O)(=O)CC3)nc2CN1C(=O)N1CCN(C)C[C@@H]1c1ccccc1	InChI=1S/C25H34N6O3S/c1-18-14-20-15-26-24(27-21-8-12-35(33,34)13-9-21)28-22(20)16-31(18)25(32)30-11-10-29(2)17-23(30)19-6-4-3-5-7-19/h3-7,15,18,21,23H,8-14,16-17H2,1-2H3,(H,26,27,28)/t18-,23-/m1/s1	VINIZKSQBWUQIG-WZONZLPQSA-N	530428	WO2022064009, Compound 214	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 16							WIPO		10.7270/Q2MC936B		aid1806201	WO2022064009	Anne, ML; Sophie, CÉ; Pascal, AC; Eddy, LY; Christophe, M	JANSSEN PHARMACEUTICA NV	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=530428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=530428&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163200357	463793907							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407579	CC(=O)N1CCN(CC1)c1ccc(Nc2nccc(n2)-c2c[nH]c3ncccc23)cc1	InChI=1S/C23H23N7O/c1-16(31)29-11-13-30(14-12-29)18-6-4-17(5-7-18)27-23-25-10-8-21(28-23)20-15-26-22-19(20)3-2-9-24-22/h2-10,15H,11-14H2,1H3,(H,24,26)(H,25,27,28)	WYGCUPDNENIRQH-UHFFFAOYSA-N	50568686	CHEMBL4864449	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568686&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164620868	471058831							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407580	CC(=O)N1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cn(C)c3ncccc23)cc1	InChI=1S/C24H25N7O/c1-17(32)30-12-14-31(15-13-30)19-7-5-18(6-8-19)27-24-26-11-9-22(28-24)21-16-29(2)23-20(21)4-3-10-25-23/h3-11,16H,12-15H2,1-2H3,(H,26,27,28)	KXWJHAJGDMNFNU-UHFFFAOYSA-N	50568687	CHEMBL4876697	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568687&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164627996	471058832							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407581	CN1CCN(CC1)c1cccc(Nc2nccc(n2)-c2c[nH]c3ncccc23)c1	InChI=1S/C22H23N7/c1-28-10-12-29(13-11-28)17-5-2-4-16(14-17)26-22-24-9-7-20(27-22)19-15-25-21-18(19)6-3-8-23-21/h2-9,14-15H,10-13H2,1H3,(H,23,25)(H,24,26,27)	IGIRIPQQEQZJIY-UHFFFAOYSA-N	50568688	CHEMBL4862206	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 142								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568688&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164622555	471058833							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407582	CN1CCN(CC1)c1cccc(Nc2nccc(n2)-c2cn(C)c3ncccc23)c1	InChI=1S/C23H25N7/c1-28-11-13-30(14-12-28)18-6-3-5-17(15-18)26-23-25-10-8-21(27-23)20-16-29(2)22-19(20)7-4-9-24-22/h3-10,15-16H,11-14H2,1-2H3,(H,25,26,27)	PETRMFAIRNHKGK-UHFFFAOYSA-N	50568689	CHEMBL4868609	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568689&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164623348	471058834							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407583	CC(=O)N1CCCN(CC1)c1cccc(Nc2nccc(n2)-c2c[nH]c3ncccc23)c1	InChI=1S/C24H25N7O/c1-17(32)30-11-4-12-31(14-13-30)19-6-2-5-18(15-19)28-24-26-10-8-22(29-24)21-16-27-23-20(21)7-3-9-25-23/h2-3,5-10,15-16H,4,11-14H2,1H3,(H,25,27)(H,26,28,29)	JISLYHZGPUPOHU-UHFFFAOYSA-N	50568690	CHEMBL4870188	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 29								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568690&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164619797	471058835							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407584	CC(=O)N1CCCN(CC1)c1cccc(Nc2nccc(n2)-c2cnc3n(C)cccc23)c1	InChI=1S/C25H27N7O/c1-18(33)31-12-5-13-32(15-14-31)20-7-3-6-19(16-20)28-25-26-10-9-23(29-25)22-17-27-24-21(22)8-4-11-30(24)2/h3-4,6-11,16-17H,5,12-15H2,1-2H3,(H,26,28,29)	OADVNCSNMCTMIX-UHFFFAOYSA-N	50568691	CHEMBL4871011	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568691&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164624302	471058836							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407585	CC(=O)N1CCN(CC1)c1ccc(Nc2nccc(n2)-c2c[nH]c3cccnc23)cc1	InChI=1S/C23H23N7O/c1-16(31)29-11-13-30(14-12-29)18-6-4-17(5-7-18)27-23-25-10-8-20(28-23)19-15-26-21-3-2-9-24-22(19)21/h2-10,15,26H,11-14H2,1H3,(H,25,27,28)	PTEAZMJTOCQRPT-UHFFFAOYSA-N	50568692	CHEMBL4862054	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568692&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164623958	471058837							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407586	CN1CCN(CC1)c1cccc(Nc2nccc(n2)-c2c[nH]c3cccnc23)c1	InChI=1S/C22H23N7/c1-28-10-12-29(13-11-28)17-5-2-4-16(14-17)26-22-24-9-7-19(27-22)18-15-25-20-6-3-8-23-21(18)20/h2-9,14-15,25H,10-13H2,1H3,(H,24,26,27)	IPFHPUNNVNIMJV-UHFFFAOYSA-N	50568693	CHEMBL4873875	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568693&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164619899	471058838							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407587	CC(=O)N1CCCN(CC1)c1cccc(Nc2nccc(n2)-c2c[nH]c3cccnc23)c1	InChI=1S/C24H25N7O/c1-17(32)30-11-4-12-31(14-13-30)19-6-2-5-18(15-19)28-24-26-10-8-21(29-24)20-16-27-22-7-3-9-25-23(20)22/h2-3,5-10,15-16,27H,4,11-14H2,1H3,(H,26,28,29)	CAQPJACOYCYQDB-UHFFFAOYSA-N	50568694	CHEMBL4850334	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568694&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164614979	471058839							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407588	CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1	InChI=1S/C29H44N8O3/c1-4-23-28(31-20-9-17-40-18-10-20)34-29(26(33-23)27(30)38)32-21-5-6-24(25(19-21)39-3)37-11-7-22(8-12-37)36-15-13-35(2)14-16-36/h5-6,19-20,22H,4,7-18H2,1-3H3,(H2,30,38)(H2,31,32,34)	GYQYAJJFPNQOOW-UHFFFAOYSA-N	144315	Gilteritinib::US11512074, Example T-9::US8969336, 547::US8969336, 577	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=144315	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=144315&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	C6F	7AB1,6JQR	49803313	251973536							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407589	CC(=O)N1CCN(CC1)c1ccc(Nc2nccc(n2)-c2c[nH]c3ccccc23)cc1	InChI=1S/C24H24N6O/c1-17(31)29-12-14-30(15-13-29)19-8-6-18(7-9-19)27-24-25-11-10-23(28-24)21-16-26-22-5-3-2-4-20(21)22/h2-11,16,26H,12-15H2,1H3,(H,25,27,28)	OLXWBUJYFIIWAY-UHFFFAOYSA-N	50568695	CHEMBL4865261	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568695&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			11625762	471058840							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407590	CC(=O)N1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cn(C)c3ccccc23)cc1	InChI=1S/C25H26N6O/c1-18(32)30-13-15-31(16-14-30)20-9-7-19(8-10-20)27-25-26-12-11-23(28-25)22-17-29(2)24-6-4-3-5-21(22)24/h3-12,17H,13-16H2,1-2H3,(H,26,27,28)	YOKHLVWWBFXTHA-UHFFFAOYSA-N	50568696	CHEMBL4866358	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568696&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			11510156	471058841							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407591	CC(=O)N1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cn(c3ccccc23)S(=O)(=O)c2ccc(C)cc2)cc1	InChI=1S/C31H30N6O3S/c1-22-7-13-26(14-8-22)41(39,40)37-21-28(27-5-3-4-6-30(27)37)29-15-16-32-31(34-29)33-24-9-11-25(12-10-24)36-19-17-35(18-20-36)23(2)38/h3-16,21H,17-20H2,1-2H3,(H,32,33,34)	XWAXWDPAAMQUQH-UHFFFAOYSA-N	50568697	CHEMBL4869365	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568697&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164622381	471058842							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407592	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(C#N)c(n2)-c2c[nH]c3ccccc23)cc1	InChI=1S/C25H23N7O/c1-17(33)31-10-12-32(13-11-31)20-8-6-19(7-9-20)29-25-28-15-18(14-26)24(30-25)22-16-27-23-5-3-2-4-21(22)23/h2-9,15-16,27H,10-13H2,1H3,(H,28,29,30)	PBBWSPGXHCOBSP-UHFFFAOYSA-N	50568698	CHEMBL4855435	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 426								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568698&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164611838	471058843							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407593	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(C#N)c(n2)-c2cn(C)c3ccccc23)cc1	InChI=1S/C26H25N7O/c1-18(34)32-11-13-33(14-12-32)21-9-7-20(8-10-21)29-26-28-16-19(15-27)25(30-26)23-17-31(2)24-6-4-3-5-22(23)24/h3-10,16-17H,11-14H2,1-2H3,(H,28,29,30)	NSMGEZSPFGMTPE-UHFFFAOYSA-N	50568699	CHEMBL4866028	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 1625								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568699&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164625576	471058844							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407594	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(C#N)c(n2)-c2c(C)[nH]c3ccccc23)cc1	InChI=1S/C26H25N7O/c1-17-24(22-5-3-4-6-23(22)29-17)25-19(15-27)16-28-26(31-25)30-20-7-9-21(10-8-20)33-13-11-32(12-14-33)18(2)34/h3-10,16,29H,11-14H2,1-2H3,(H,28,30,31)	PZGXSHMVAJZHIL-UHFFFAOYSA-N	50568700	CHEMBL4856641	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 536								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568700&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164612416	471058845							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407595	CC(=O)N1CCN(CC1)c1ccc(Nc2nccc(n2)-c2n[nH]c3ccccc23)cc1	InChI=1S/C23H23N7O/c1-16(31)29-12-14-30(15-13-29)18-8-6-17(7-9-18)25-23-24-11-10-21(26-23)22-19-4-2-3-5-20(19)27-28-22/h2-11H,12-15H2,1H3,(H,27,28)(H,24,25,26)	QNCJSYGDOXQRQP-UHFFFAOYSA-N	50568701	CHEMBL4847825	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568701&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164618267	471058846							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407596	CC(=O)N1CCN(CC1)c1ccc(Nc2nccc(n2)-c2nn(C)c3ccccc23)cc1	InChI=1S/C24H25N7O/c1-17(32)30-13-15-31(16-14-30)19-9-7-18(8-10-19)26-24-25-12-11-21(27-24)23-20-5-3-4-6-22(20)29(2)28-23/h3-12H,13-16H2,1-2H3,(H,25,26,27)	XBLAREFJDPHRAT-UHFFFAOYSA-N	50568702	CHEMBL4848999	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568702&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164614919	471058847							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407597	CC(=O)N1CCN(CC1)c1ccc(Nc2ncc(C#N)c(n2)-c2n[nH]c3ccccc23)cc1	InChI=1S/C24H22N8O/c1-16(33)31-10-12-32(13-11-31)19-8-6-18(7-9-19)27-24-26-15-17(14-25)22(28-24)23-20-4-2-3-5-21(20)29-30-23/h2-9,15H,10-13H2,1H3,(H,29,30)(H,26,27,28)	OTJZJRVZMBHHJE-UHFFFAOYSA-N	50568703	CHEMBL4878159	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568703&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164627298	471058848							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51407598	CC(=O)N1CCCN(CC1)c1cccc(Nc2nccc(n2)-c2n[nH]c3ccccc23)c1	InChI=1S/C24H25N7O/c1-17(32)30-12-5-13-31(15-14-30)19-7-4-6-18(16-19)26-24-25-11-10-22(27-24)23-20-8-2-3-9-21(20)28-29-23/h2-4,6-11,16H,5,12-15H2,1H3,(H,28,29)(H,25,26,27)	IHLNWRDTNQHABM-UHFFFAOYSA-N	50568704	CHEMBL4867869	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	>5000								ChEMBL	10.1016/j.ejmech.2021.113215	10.7270/Q22Z198K	33516985			Long, Y; Yu, M; Ochnik, AM; Karanjia, JD; Basnet, SK; Kebede, AA; Kou, L; Wang, S	University of South Australia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50568704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50568704&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164619722	471058849							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51412832	CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(CC3)C(=O)CCl)nc2n(C2CCCC2)c1=O	InChI=1S/C26H30ClN7O3/c1-16-20-15-29-26(31-24(20)34(18-5-3-4-6-18)25(37)23(16)17(2)35)30-21-8-7-19(14-28-21)32-9-11-33(12-10-32)22(36)13-27/h7-8,14-15,18H,3-6,9-13H2,1-2H3,(H,28,29,30,31)	DHXAFRBSJGTAFK-UHFFFAOYSA-N	50570698	CHEMBL4850687	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>3333							ChEMBL	10.1016/j.ejmech.2021.113432	10.7270/Q28S4TQW	33857728			Shan, H; Ma, X; Yan, G; Luo, M; Zhong, X; Lan, S; Yang, J; Liu, Y; Pu, C; Tong, Y; Li, R	Sichuan University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50570698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50570698&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			162424469	471060843							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207763	Fc1cccc2nc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc12	InChI=1S/C22H20FN5O2/c1-2-20(29)25-15-8-6-14(7-9-15)21(30)28-11-10-16(13-28)26-22-24-12-17-18(23)4-3-5-19(17)27-22/h2-9,12,16H,1,10-11,13H2,(H,25,29)(H,24,26,27)/t16-/m1/s1	CIECLIQCGMZLNI-MRXNPFEDSA-N	572126	(R)-N-(4-(3-((5-fluoroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 91	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572126&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149905793	473133198							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207766	Cc1cc(ccc1NC(=O)C=C)C(=O)N1CC[C@H](C1)Nc1ncc2cc(F)ccc2n1	InChI=1S/C23H22FN5O2/c1-3-21(30)27-19-6-4-15(10-14(19)2)22(31)29-9-8-18(13-29)26-23-25-12-16-11-17(24)5-7-20(16)28-23/h3-7,10-12,18H,1,8-9,13H2,2H3,(H,27,30)(H,25,26,28)/t18-/m1/s1	KXKAWIWAQIOGGO-GOSISDBHSA-N	572127	(R)-N-(4-(3-((6-fluoroquinazolin-2- yl)amino)pyrrolidine-1-carbonyl)-2- methylphenyl)acrylamide::US11447493, Example 92	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572127	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572127&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150887829	473133199							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207769	Cc1cc(ccc1NC(=O)C=C)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(cc2n1)S(C)(=O)=O	InChI=1S/C24H25N5O4S/c1-4-22(30)27-20-8-6-16(11-15(20)2)23(31)29-10-9-18(14-29)26-24-25-13-17-5-7-19(34(3,32)33)12-21(17)28-24/h4-8,11-13,18H,1,9-10,14H2,2-3H3,(H,27,30)(H,25,26,28)/t18-/m1/s1	RZAUUURMPYOKSI-GOSISDBHSA-N	572128	(R)-N-(2-methyl-4-(3-((7- (methylsulfonyl)quinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 93	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572128&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151803164	473133200							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207772	CCC(=C)C(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C24H25N5O2/c1-3-16(2)22(30)26-19-10-8-17(9-11-19)23(31)29-13-12-20(15-29)27-24-25-14-18-6-4-5-7-21(18)28-24/h4-11,14,20H,2-3,12-13,15H2,1H3,(H,26,30)(H,25,27,28)/t20-/m1/s1	JKHQLEAMZNVIPI-HXUWFJFHSA-N	572129	(R)-2-methylene-N-(4-(3- (quinazolin-2-ylamino)pyrrolidine-1- carbonyl)phenyl)butanamide::US11447493, Example 94	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572129&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150693148	473133201							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207775	C=CS(=O)(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C21H21N5O3S/c1-2-30(28,29)25-17-9-7-15(8-10-17)20(27)26-12-11-18(14-26)23-21-22-13-16-5-3-4-6-19(16)24-21/h2-10,13,18,25H,1,11-12,14H2,(H,22,23,24)/t18-/m1/s1	QSERWBXLEKAYCJ-GOSISDBHSA-N	572130	(R)-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)ethenesulfonamide::US11447493, Example 95	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572130&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151639378	473133202							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207778	C[C@H]1CN(C[C@@H]1Nc1ncc2ccccc2n1)C(=O)c1ccc(NC(=O)C=C)cc1	InChI=1S/C23H23N5O2/c1-3-21(29)25-18-10-8-16(9-11-18)22(30)28-13-15(2)20(14-28)27-23-24-12-17-6-4-5-7-19(17)26-23/h3-12,15,20H,1,13-14H2,2H3,(H,25,29)(H,24,26,27)/t15-,20-/m0/s1	GRBMJJYBCNETMC-YWZLYKJASA-N	572131	N-(4-((3S,4R)-3-methyl-4- (quinazolin-2-ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 96	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 20000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572131	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572131&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150337889	473133203							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207454	C=CC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H23N5O2/c1-2-21(29)25-18-11-9-16(10-12-18)22(30)28-13-5-7-19(15-28)26-23-24-14-17-6-3-4-8-20(17)27-23/h2-4,6,8-12,14,19H,1,5,7,13,15H2,(H,25,29)(H,24,26,27)/t19-/m1/s1	GWRDYNFOVJSTIH-LJQANCHMSA-N	572033	(R)-N-(4-(3-(quinazolin-2- ylamino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572033	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572033&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			147721568	473133106							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207457	C=CC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1cc2ccccc2cn1	InChI=1S/C24H24N4O2/c1-2-23(29)27-20-11-9-17(10-12-20)24(30)28-13-5-8-21(16-28)26-22-14-18-6-3-4-7-19(18)15-25-22/h2-4,6-7,9-12,14-15,21H,1,5,8,13,16H2,(H,25,26)(H,27,29)/t21-/m1/s1	BJQKZYVLMUWQLN-OAQYLSRUSA-N	572037	(R)-N-(4-(3-(isoquinolin-3- ylamino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 2	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572037	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572037&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			147095490	473133110							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207460	Clc1ccc2nc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2c1	InChI=1S/C23H22ClN5O2/c1-2-21(30)26-18-8-5-15(6-9-18)22(31)29-11-3-4-19(14-29)27-23-25-13-16-12-17(24)7-10-20(16)28-23/h2,5-10,12-13,19H,1,3-4,11,14H2,(H,26,30)(H,25,27,28)/t19-/m1/s1	OCDGUPGJTXDKQV-LJQANCHMSA-N	572038	(R)-N-(4-(3-((6-chloroquinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 3	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572038&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			148737250	473133111							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207462	Fc1ccc2nc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2c1	InChI=1S/C23H22FN5O2/c1-2-21(30)26-18-8-5-15(6-9-18)22(31)29-11-3-4-19(14-29)27-23-25-13-16-12-17(24)7-10-20(16)28-23/h2,5-10,12-13,19H,1,3-4,11,14H2,(H,26,30)(H,25,27,28)/t19-/m1/s1	DWWSHEDDRAZIRR-LJQANCHMSA-N	572039	(R)-N-(4-(3-((6-fluoroquinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 4	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572039&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150109204	473133112							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207464	Fc1ccc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C23H22FN5O2/c1-2-21(30)26-18-9-6-15(7-10-18)22(31)29-11-3-4-19(14-29)27-23-25-13-16-5-8-17(24)12-20(16)28-23/h2,5-10,12-13,19H,1,3-4,11,14H2,(H,26,30)(H,25,27,28)/t19-/m1/s1	IGYWYLYPEQDROD-LJQANCHMSA-N	572040	(R)-N-(4-(3-((7-fluoroquinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 5	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572040	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572040&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			147915447	473133113							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207467	COc1ccc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C24H25N5O3/c1-3-22(30)26-18-9-6-16(7-10-18)23(31)29-12-4-5-19(15-29)27-24-25-14-17-8-11-20(32-2)13-21(17)28-24/h3,6-11,13-14,19H,1,4-5,12,15H2,2H3,(H,26,30)(H,25,27,28)/t19-/m1/s1	UYMLPZXKVJTMDC-LJQANCHMSA-N	572041	(R)-N-(4-(3-((7-methoxyquinazolin- 2-yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 6	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572041	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572041&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152089900	473133114							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207470	COc1ccc2nc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2c1	InChI=1S/C24H25N5O3/c1-3-22(30)26-18-8-6-16(7-9-18)23(31)29-12-4-5-19(15-29)27-24-25-14-17-13-20(32-2)10-11-21(17)28-24/h3,6-11,13-14,19H,1,4-5,12,15H2,2H3,(H,26,30)(H,25,27,28)/t19-/m1/s1	YUBUDGLTAQSHRH-LJQANCHMSA-N	572042	(R)-N-(4-(3-((6-methoxyquinazolin- 2-yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 7	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572042&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152584032	473133115							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207473	Cc1ccc2nc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2c1	InChI=1S/C24H25N5O2/c1-3-22(30)26-19-9-7-17(8-10-19)23(31)29-12-4-5-20(15-29)27-24-25-14-18-13-16(2)6-11-21(18)28-24/h3,6-11,13-14,20H,1,4-5,12,15H2,2H3,(H,26,30)(H,25,27,28)/t20-/m1/s1	IDAOACOGMHNOPC-HXUWFJFHSA-N	572043	(R)-N-(4-(3-((6-methylquinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 8	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572043	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572043&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			147894509	473133116							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207476	Cc1ccc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C24H25N5O2/c1-3-22(30)26-19-10-8-17(9-11-19)23(31)29-12-4-5-20(15-29)27-24-25-14-18-7-6-16(2)13-21(18)28-24/h3,6-11,13-14,20H,1,4-5,12,15H2,2H3,(H,26,30)(H,25,27,28)/t20-/m1/s1	SOLCFLIAEVHGHM-HXUWFJFHSA-N	572044	(R)-N-(4-(3-((7-methylquinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 9	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572044	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572044&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151879657	473133117							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207478	Clc1ccc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C23H22ClN5O2/c1-2-21(30)26-18-9-6-15(7-10-18)22(31)29-11-3-4-19(14-29)27-23-25-13-16-5-8-17(24)12-20(16)28-23/h2,5-10,12-13,19H,1,3-4,11,14H2,(H,26,30)(H,25,27,28)/t19-/m1/s1	YEUXYLMZOGKIDT-LJQANCHMSA-N	572045	(R)-N-(4-(3-((7-chloroquinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 10	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572045	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572045&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152507678	473133118							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207481	CS(=O)(=O)c1ccc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C24H25N5O4S/c1-3-22(30)26-18-9-6-16(7-10-18)23(31)29-12-4-5-19(15-29)27-24-25-14-17-8-11-20(34(2,32)33)13-21(17)28-24/h3,6-11,13-14,19H,1,4-5,12,15H2,2H3,(H,26,30)(H,25,27,28)/t19-/m1/s1	MPOVNMQJTKXOAG-LJQANCHMSA-N	572046	(R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 11	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572046	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572046&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151108360	473133119							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207484	CN(C)C(=O)c1ccc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C26H28N6O3/c1-4-23(33)28-20-11-9-17(10-12-20)25(35)32-13-5-6-21(16-32)29-26-27-15-19-8-7-18(14-22(19)30-26)24(34)31(2)3/h4,7-12,14-15,21H,1,5-6,13,16H2,2-3H3,(H,28,33)(H,27,29,30)/t21-/m1/s1	HQFIWJKVWLGQPU-OAQYLSRUSA-N	572047	(R)-2-((1-(4- acrylamidobenzoyl)piperidin-3- yl)amino)-N,N-dimethylquinazoline- 7-carboxamide::US11447493, Example 12	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572047	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572047&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150463238	473133120							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207487	NC(=O)c1ccc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C24H24N6O3/c1-2-21(31)27-18-9-7-15(8-10-18)23(33)30-11-3-4-19(14-30)28-24-26-13-17-6-5-16(22(25)32)12-20(17)29-24/h2,5-10,12-13,19H,1,3-4,11,14H2,(H2,25,32)(H,27,31)(H,26,28,29)/t19-/m1/s1	OBHIERMOPIJJOL-LJQANCHMSA-N	572048	(R)-2-((1-(4- acrylamidobenzoyl)piperidin-3- yl)amino)quinazoline-7-carboxamide::US11447493, Example 13	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 20000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572048	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572048&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151295384	473133121							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207490	OC(=O)c1ccc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C24H23N5O4/c1-2-21(30)26-18-9-7-15(8-10-18)22(31)29-11-3-4-19(14-29)27-24-25-13-17-6-5-16(23(32)33)12-20(17)28-24/h2,5-10,12-13,19H,1,3-4,11,14H2,(H,26,30)(H,32,33)(H,25,27,28)/t19-/m1/s1	CMILELPCKPBWNV-LJQANCHMSA-N	572049	(R)-2-((1-(4- acrylamidobenzoyl)piperidin-3- yl)amino)quinazoline-7-carboxylic acid::US11447493, Example 14	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 20000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572049	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572049&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149926589	473133122							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207493	CC(C)n1c2nc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2ccc1=O	InChI=1S/C25H28N6O3/c1-4-21(32)27-19-10-7-17(8-11-19)24(34)30-13-5-6-20(15-30)28-25-26-14-18-9-12-22(33)31(16(2)3)23(18)29-25/h4,7-12,14,16,20H,1,5-6,13,15H2,2-3H3,(H,27,32)(H,26,28,29)/t20-/m1/s1	ZPFYVLDGCDZJCW-HXUWFJFHSA-N	572050	(R)-N-(4-(3-((8-isopropyl-7-oxo-7,8- dihydropyrido[2,3-d]pyrimidin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 15	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572050	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572050&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152689330	473133123							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207496	C=CC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2ccc(=O)[nH]c2n1			572051	(R)-N-(4-(3-((7-oxo-7,8- dihydropyrido[2,3-d]pyrimidin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 16	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572051&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			165437189	473133124							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207499	CCC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H25N5O2/c1-2-21(29)25-18-11-9-16(10-12-18)22(30)28-13-5-7-19(15-28)26-23-24-14-17-6-3-4-8-20(17)27-23/h3-4,6,8-12,14,19H,2,5,7,13,15H2,1H3,(H,25,29)(H,24,26,27)/t19-/m1/s1	VMTBHEBGKDRQTD-LJQANCHMSA-N	572052	(R)-N-(4-(3-(quinazolin-2- ylamino)piperidine-1- carbonyl)phenyl)propionamide::US11447493, Example 17	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572052	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572052&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086768	473133125							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207502	CCC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1cc2ccccc2cn1	InChI=1S/C24H26N4O2/c1-2-23(29)27-20-11-9-17(10-12-20)24(30)28-13-5-8-21(16-28)26-22-14-18-6-3-4-7-19(18)15-25-22/h3-4,6-7,9-12,14-15,21H,2,5,8,13,16H2,1H3,(H,25,26)(H,27,29)/t21-/m1/s1	OANGEVCXQHVZRE-OAQYLSRUSA-N	572053	(R)-N-(4-(3-(isoquinolin-3- ylamino)piperidine-1- carbonyl)phenyl)propionamide::US11447493, Example 18	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572053&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086881	473133126							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207505	CCC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2cc(Cl)ccc2n1	InChI=1S/C23H24ClN5O2/c1-2-21(30)26-18-8-5-15(6-9-18)22(31)29-11-3-4-19(14-29)27-23-25-13-16-12-17(24)7-10-20(16)28-23/h5-10,12-13,19H,2-4,11,14H2,1H3,(H,26,30)(H,25,27,28)/t19-/m1/s1	MLHCNCBAGXONLE-LJQANCHMSA-N	572054	(R)-N-(4-(3-((6-chloroquinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)propionamide::US11447493, Example 19	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572054&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086840	473133127							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207508	CCC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2ccc(OC)cc2n1	InChI=1S/C24H27N5O3/c1-3-22(30)26-18-9-6-16(7-10-18)23(31)29-12-4-5-19(15-29)27-24-25-14-17-8-11-20(32-2)13-21(17)28-24/h6-11,13-14,19H,3-5,12,15H2,1-2H3,(H,26,30)(H,25,27,28)/t19-/m1/s1	ZOGMUJPGFSULRA-LJQANCHMSA-N	572055	(R)-N-(4-(3-((7-methoxyquinazolin- 2-yl)amino)piperidine-1- carbonyl)phenyl)propionamide::US11447493, Example 20	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572055&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149539821	473133128							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207511	CCC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2ccc(cc2n1)S(C)(=O)=O	InChI=1S/C24H27N5O4S/c1-3-22(30)26-18-9-6-16(7-10-18)23(31)29-12-4-5-19(15-29)27-24-25-14-17-8-11-20(34(2,32)33)13-21(17)28-24/h6-11,13-14,19H,3-5,12,15H2,1-2H3,(H,26,30)(H,25,27,28)/t19-/m1/s1	PWFBWQNBRPTGSB-LJQANCHMSA-N	572056	(R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)propionamide::US11447493, Example 21	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572056	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572056&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086855	473133129							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207514	CCC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2ccc(Cl)cc2n1	InChI=1S/C23H24ClN5O2/c1-2-21(30)26-18-9-6-15(7-10-18)22(31)29-11-3-4-19(14-29)27-23-25-13-16-5-8-17(24)12-20(16)28-23/h5-10,12-13,19H,2-4,11,14H2,1H3,(H,26,30)(H,25,27,28)/t19-/m1/s1	YOZIGRVBNKWGQI-LJQANCHMSA-N	572057	(R)-N-(4-(3-((7-chloroquinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)propionamide::US11447493, Example 22	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572057	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572057&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086850	473133130							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207517	CCC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2ccc(F)cc2n1	InChI=1S/C23H24FN5O2/c1-2-21(30)26-18-9-6-15(7-10-18)22(31)29-11-3-4-19(14-29)27-23-25-13-16-5-8-17(24)12-20(16)28-23/h5-10,12-13,19H,2-4,11,14H2,1H3,(H,26,30)(H,25,27,28)/t19-/m1/s1	BOMYALWKPBXPTK-LJQANCHMSA-N	572058	(R)-N-(4-(3-((7-fluoroquinazolin-2- yl)amino)piperidine-1- carbonyl)phenyl)propionamide::US11447493, Example 23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572058	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572058&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086880	473133131							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207520	CCC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2ccc(=O)n(C(C)C)c2n1	InChI=1S/C25H30N6O3/c1-4-21(32)27-19-10-7-17(8-11-19)24(34)30-13-5-6-20(15-30)28-25-26-14-18-9-12-22(33)31(16(2)3)23(18)29-25/h7-12,14,16,20H,4-6,13,15H2,1-3H3,(H,27,32)(H,26,28,29)/t20-/m1/s1	LCOFGIFLLYDPNW-HXUWFJFHSA-N	572059	(R)-N-(4-(3-((8-isopropyl-7-oxo-7,8- dihydropyrido[2,3-d]pyrimidin-2- yl)amino)piperidine-1- carbonyl)phenyl)propionamide::US11447493, Example 24	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572059	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572059&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086795	473133132							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207523	Clc1ccc2nc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2c1	InChI=1S/C22H20ClN5O2/c1-2-20(29)25-17-6-3-14(4-7-17)21(30)28-10-9-18(13-28)26-22-24-12-15-11-16(23)5-8-19(15)27-22/h2-8,11-12,18H,1,9-10,13H2,(H,25,29)(H,24,26,27)/t18-/m1/s1	KACPNCDTDQJOPU-GOSISDBHSA-N	572060	(R)-N-(4-(3-((6-chloroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 25	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572060&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150772280	473133133							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207528	C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C22H21N5O2/c1-2-20(28)24-17-9-7-15(8-10-17)21(29)27-12-11-18(14-27)25-22-23-13-16-5-3-4-6-19(16)26-22/h2-10,13,18H,1,11-12,14H2,(H,24,28)(H,23,25,26)/t18-/m1/s1	PFCFIGDMUIPBGY-GOSISDBHSA-N	572061	(R)-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 26	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572061	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572061&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151443945	473133134							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207529	C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C22H21N5O2/c1-2-20(28)24-17-9-7-15(8-10-17)21(29)27-12-11-18(14-27)25-22-23-13-16-5-3-4-6-19(16)26-22/h2-10,13,18H,1,11-12,14H2,(H,24,28)(H,23,25,26)/t18-/m1/s1	PFCFIGDMUIPBGY-GOSISDBHSA-N	572061	(R)-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 26	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572061	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572061&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151443945	473133134							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207534	C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1cc2ccccc2cn1	InChI=1S/C23H22N4O2/c1-2-22(28)26-19-9-7-16(8-10-19)23(29)27-12-11-20(15-27)25-21-13-17-5-3-4-6-18(17)14-24-21/h2-10,13-14,20H,1,11-12,15H2,(H,24,25)(H,26,28)/t20-/m1/s1	CKXQPVNWDKKSSJ-HXUWFJFHSA-N	572062	(R)-N-(4-(3-(isoquinolin-3- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 27	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572062	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572062&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149919567	473133135							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207535	C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1cc2ccccc2cn1	InChI=1S/C23H22N4O2/c1-2-22(28)26-19-9-7-16(8-10-19)23(29)27-12-11-20(15-27)25-21-13-17-5-3-4-6-18(17)14-24-21/h2-10,13-14,20H,1,11-12,15H2,(H,24,25)(H,26,28)/t20-/m1/s1	CKXQPVNWDKKSSJ-HXUWFJFHSA-N	572062	(R)-N-(4-(3-(isoquinolin-3- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 27	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572062	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572062&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149919567	473133135							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207540	Fc1ccc2nc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2c1	InChI=1S/C22H20FN5O2/c1-2-20(29)25-17-6-3-14(4-7-17)21(30)28-10-9-18(13-28)26-22-24-12-15-11-16(23)5-8-19(15)27-22/h2-8,11-12,18H,1,9-10,13H2,(H,25,29)(H,24,26,27)/t18-/m1/s1	QVWJCPCDKVFGTB-GOSISDBHSA-N	572063	(R)-N-(4-(3-((6-fluoroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 28	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572063	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572063&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151657742	473133136							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207541	Fc1ccc2nc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2c1	InChI=1S/C22H20FN5O2/c1-2-20(29)25-17-6-3-14(4-7-17)21(30)28-10-9-18(13-28)26-22-24-12-15-11-16(23)5-8-19(15)27-22/h2-8,11-12,18H,1,9-10,13H2,(H,25,29)(H,24,26,27)/t18-/m1/s1	QVWJCPCDKVFGTB-GOSISDBHSA-N	572063	(R)-N-(4-(3-((6-fluoroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 28	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572063	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572063&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151657742	473133136							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207544	COc1ccc2nc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2c1	InChI=1S/C23H23N5O3/c1-3-21(29)25-17-6-4-15(5-7-17)22(30)28-11-10-18(14-28)26-23-24-13-16-12-19(31-2)8-9-20(16)27-23/h3-9,12-13,18H,1,10-11,14H2,2H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	PWIPCKSOLCEBRW-GOSISDBHSA-N	572064	(R)-N-(4-(3-((6-methoxyquinazolin- 2-yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 29	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572064	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572064&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151530374	473133137							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207547	Cc1ccc2nc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2c1	InChI=1S/C23H23N5O2/c1-3-21(29)25-18-7-5-16(6-8-18)22(30)28-11-10-19(14-28)26-23-24-13-17-12-15(2)4-9-20(17)27-23/h3-9,12-13,19H,1,10-11,14H2,2H3,(H,25,29)(H,24,26,27)/t19-/m1/s1	NLZHDSMHJXZJTG-LJQANCHMSA-N	572065	(R)-N-(4-(3-((6-methylquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 30	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572065	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572065&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			148651385	473133138							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207550	C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccncc2n1	InChI=1S/C21H20N6O2/c1-2-19(28)24-16-5-3-14(4-6-16)20(29)27-10-8-17(13-27)25-21-23-11-15-7-9-22-12-18(15)26-21/h2-7,9,11-12,17H,1,8,10,13H2,(H,24,28)(H,23,25,26)/t17-/m1/s1	JVPPVCXAHQZJPI-QGZVFWFLSA-N	572066	(R)-N-(4-(3-(pyrido[3,4-d]pyrimidin- 2-ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 31	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572066	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572066&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150749774	473133139							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207553	Cc1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C23H23N5O2/c1-3-21(29)25-18-8-6-16(7-9-18)22(30)28-11-10-19(14-28)26-23-24-13-17-5-4-15(2)12-20(17)27-23/h3-9,12-13,19H,1,10-11,14H2,2H3,(H,25,29)(H,24,26,27)/t19-/m1/s1	YRQZGISKFWGSDA-LJQANCHMSA-N	572067	(R)-N-(4-(3-((7-methylquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 32	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572067	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572067&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152571954	473133140							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207558	CS(=O)(=O)c1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C23H23N5O4S/c1-3-21(29)25-17-7-4-15(5-8-17)22(30)28-11-10-18(14-28)26-23-24-13-16-6-9-19(33(2,31)32)12-20(16)27-23/h3-9,12-13,18H,1,10-11,14H2,2H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	FGELSDGMZMOQHT-GOSISDBHSA-N	572068	(R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 33	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572068	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572068&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150155698	473133141							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207559	CS(=O)(=O)c1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C23H23N5O4S/c1-3-21(29)25-17-7-4-15(5-8-17)22(30)28-11-10-18(14-28)26-23-24-13-16-6-9-19(33(2,31)32)12-20(16)27-23/h3-9,12-13,18H,1,10-11,14H2,2H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	FGELSDGMZMOQHT-GOSISDBHSA-N	572068	(R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 33	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572068	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572068&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150155698	473133141							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207564	COc1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C23H23N5O3/c1-3-21(29)25-17-7-4-15(5-8-17)22(30)28-11-10-18(14-28)26-23-24-13-16-6-9-19(31-2)12-20(16)27-23/h3-9,12-13,18H,1,10-11,14H2,2H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	ADHABGMDGASWTO-GOSISDBHSA-N	572069	(R)-N-(4-(3-((7-methoxyquinazolin- 2-yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 34	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572069	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572069&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149621800	473133142							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207565	COc1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C23H23N5O3/c1-3-21(29)25-17-7-4-15(5-8-17)22(30)28-11-10-18(14-28)26-23-24-13-16-6-9-19(31-2)12-20(16)27-23/h3-9,12-13,18H,1,10-11,14H2,2H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	ADHABGMDGASWTO-GOSISDBHSA-N	572069	(R)-N-(4-(3-((7-methoxyquinazolin- 2-yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 34	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572069	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572069&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149621800	473133142							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207568	Fc1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C22H20FN5O2/c1-2-20(29)25-17-7-4-14(5-8-17)21(30)28-10-9-18(13-28)26-22-24-12-15-3-6-16(23)11-19(15)27-22/h2-8,11-12,18H,1,9-10,13H2,(H,25,29)(H,24,26,27)/t18-/m1/s1	AJSYOLPHCHQLPB-GOSISDBHSA-N	572070	(R)-N-(4-(3-((7-fluoroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 35	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572070	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572070&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149654063	473133143							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207571	Clc1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C22H20ClN5O2/c1-2-20(29)25-17-7-4-14(5-8-17)21(30)28-10-9-18(13-28)26-22-24-12-15-3-6-16(23)11-19(15)27-22/h2-8,11-12,18H,1,9-10,13H2,(H,25,29)(H,24,26,27)/t18-/m1/s1	HWTFMLLJQLAKMY-GOSISDBHSA-N	572071	(R)-N-(4-(3-((7-chloroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 36	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572071	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572071&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			147861266	473133144							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207576	C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(cc2n1)C#N	InChI=1S/C23H20N6O2/c1-2-21(30)26-18-7-5-16(6-8-18)22(31)29-10-9-19(14-29)27-23-25-13-17-4-3-15(12-24)11-20(17)28-23/h2-8,11,13,19H,1,9-10,14H2,(H,26,30)(H,25,27,28)/t19-/m1/s1	ZRLQOLZZVDTUEA-LJQANCHMSA-N	572072	(R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 37	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572072	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572072&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152700448	473133145							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207577	C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(cc2n1)C#N	InChI=1S/C23H20N6O2/c1-2-21(30)26-18-7-5-16(6-8-18)22(31)29-10-9-19(14-29)27-23-25-13-17-4-3-15(12-24)11-20(17)28-23/h2-8,11,13,19H,1,9-10,14H2,(H,26,30)(H,25,27,28)/t19-/m1/s1	ZRLQOLZZVDTUEA-LJQANCHMSA-N	572072	(R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 37	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572072	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572072&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152700448	473133145							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207580	OC(=O)c1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C23H21N5O4/c1-2-20(29)25-17-7-5-14(6-8-17)21(30)28-10-9-18(13-28)26-23-24-12-16-4-3-15(22(31)32)11-19(16)27-23/h2-8,11-12,18H,1,9-10,13H2,(H,25,29)(H,31,32)(H,24,26,27)/t18-/m1/s1	JHOPNXSGIJWALX-GOSISDBHSA-N	572073	(R)-2-((1-(4- acrylamidobenzoyl)pyrrolidin-3- yl)amino)quinazoline-7-carboxylic acid::US11447493, Example 38	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572073	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572073&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150679500	473133146							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207583	NC(=O)c1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C23H22N6O3/c1-2-20(30)26-17-7-5-14(6-8-17)22(32)29-10-9-18(13-29)27-23-25-12-16-4-3-15(21(24)31)11-19(16)28-23/h2-8,11-12,18H,1,9-10,13H2,(H2,24,31)(H,26,30)(H,25,27,28)/t18-/m1/s1	BLKUOTRWYXGTQI-GOSISDBHSA-N	572074	(R)-2-((1-(4- acrylamidobenzoyl)pyrrolidin-3- yl)amino)quinazoline-7-carboxamide::US11447493, Example 39	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572074	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572074&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149792188	473133147							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207586	CNC(=O)c1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C24H24N6O3/c1-3-21(31)27-18-8-6-15(7-9-18)23(33)30-11-10-19(14-30)28-24-26-13-17-5-4-16(22(32)25-2)12-20(17)29-24/h3-9,12-13,19H,1,10-11,14H2,2H3,(H,25,32)(H,27,31)(H,26,28,29)/t19-/m1/s1	FUQXGHBWVRRQHX-LJQANCHMSA-N	572075	(R)-2-((1-(4- acrylamidobenzoyl)pyrrolidin-3- yl)amino)-N-methylquinazoline-7- carboxamide::US11447493, Example 40::US11447493, Example 58	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572075	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572075&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150226933	473133148							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207589	CN(C)C(=O)c1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C25H26N6O3/c1-4-22(32)27-19-9-7-16(8-10-19)24(34)31-12-11-20(15-31)28-25-26-14-18-6-5-17(13-21(18)29-25)23(33)30(2)3/h4-10,13-14,20H,1,11-12,15H2,2-3H3,(H,27,32)(H,26,28,29)/t20-/m1/s1	OAQWDUAHNWCUMD-HXUWFJFHSA-N	572076	(R)-2-((1-(4- acrylamidobenzoyl)pyrrolidin-3- yl)amino)-N,N-dimethylquinazoline- 7-carboxamide::US11447493, Example 41	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572076	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572076&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151292190	473133149							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207592	C=CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(=O)[nH]c2n1			572077	(R)-N-(4-(3-((7-oxo-7,8- dihydropyrido[2,3-d]pyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 42	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572077	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572077&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			165437190	473133150							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207597	CC(C)n1c2nc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2ccc1=O	InChI=1S/C24H26N6O3/c1-4-20(31)26-18-8-5-16(6-9-18)23(33)29-12-11-19(14-29)27-24-25-13-17-7-10-21(32)30(15(2)3)22(17)28-24/h4-10,13,15,19H,1,11-12,14H2,2-3H3,(H,26,31)(H,25,27,28)/t19-/m1/s1	BYNXYHOKVMMMKC-LJQANCHMSA-N	572078	(R)-N-(4-(3-((8-isopropyl-7-oxo-7,8- dihydropyrido[2,3-d]pyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 43	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572078	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572078&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149857972	473133151							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207598	CC(C)n1c2nc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)ncc2ccc1=O	InChI=1S/C24H26N6O3/c1-4-20(31)26-18-8-5-16(6-9-18)23(33)29-12-11-19(14-29)27-24-25-13-17-7-10-21(32)30(15(2)3)22(17)28-24/h4-10,13,15,19H,1,11-12,14H2,2-3H3,(H,26,31)(H,25,27,28)/t19-/m1/s1	BYNXYHOKVMMMKC-LJQANCHMSA-N	572078	(R)-N-(4-(3-((8-isopropyl-7-oxo-7,8- dihydropyrido[2,3-d]pyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 43	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572078	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572078&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149857972	473133151							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207603	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C22H23N5O2/c1-2-20(28)24-17-9-7-15(8-10-17)21(29)27-12-11-18(14-27)25-22-23-13-16-5-3-4-6-19(16)26-22/h3-10,13,18H,2,11-12,14H2,1H3,(H,24,28)(H,23,25,26)/t18-/m1/s1	CYWJCWFAPFOQOP-GOSISDBHSA-N	572079	(R)-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 44	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572079	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572079&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086847	473133152							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207604	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C22H23N5O2/c1-2-20(28)24-17-9-7-15(8-10-17)21(29)27-12-11-18(14-27)25-22-23-13-16-5-3-4-6-19(16)26-22/h3-10,13,18H,2,11-12,14H2,1H3,(H,24,28)(H,23,25,26)/t18-/m1/s1	CYWJCWFAPFOQOP-GOSISDBHSA-N	572079	(R)-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 44	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572079	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572079&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086847	473133152							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207607	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1cc2ccccc2cn1	InChI=1S/C23H24N4O2/c1-2-22(28)26-19-9-7-16(8-10-19)23(29)27-12-11-20(15-27)25-21-13-17-5-3-4-6-18(17)14-24-21/h3-10,13-14,20H,2,11-12,15H2,1H3,(H,24,25)(H,26,28)/t20-/m1/s1	HUKPFWLRPMADDJ-HXUWFJFHSA-N	572080	(R)-N-(4-(3-(isoquinolin-3- ylamino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 45	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572080	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572080&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086763	473133153							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207610	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2cc(F)ccc2n1	InChI=1S/C22H22FN5O2/c1-2-20(29)25-17-6-3-14(4-7-17)21(30)28-10-9-18(13-28)26-22-24-12-15-11-16(23)5-8-19(15)27-22/h3-8,11-12,18H,2,9-10,13H2,1H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	AXERCKVGIICWDT-GOSISDBHSA-N	572081	(R)-N-(4-(3-((6-fluoroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 46	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572081	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572081&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086805	473133154							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207613	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2cc(Cl)ccc2n1	InChI=1S/C22H22ClN5O2/c1-2-20(29)25-17-6-3-14(4-7-17)21(30)28-10-9-18(13-28)26-22-24-12-15-11-16(23)5-8-19(15)27-22/h3-8,11-12,18H,2,9-10,13H2,1H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	ZHOYYYIBRLNRRU-GOSISDBHSA-N	572082	(R)-N-(4-(3-((6-chloroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 47	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572082	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572082&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086908	473133155							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207616	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2cc(OC)ccc2n1	InChI=1S/C23H25N5O3/c1-3-21(29)25-17-6-4-15(5-7-17)22(30)28-11-10-18(14-28)26-23-24-13-16-12-19(31-2)8-9-20(16)27-23/h4-9,12-13,18H,3,10-11,14H2,1-2H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	SBDXQNJXPIKHRC-GOSISDBHSA-N	572083	(R)-N-(4-(3-((6-methoxyquinazolin- 2-yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 48	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572083	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572083&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086804	473133156							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207619	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2cc(C)ccc2n1	InChI=1S/C23H25N5O2/c1-3-21(29)25-18-7-5-16(6-8-18)22(30)28-11-10-19(14-28)26-23-24-13-17-12-15(2)4-9-20(17)27-23/h4-9,12-13,19H,3,10-11,14H2,1-2H3,(H,25,29)(H,24,26,27)/t19-/m1/s1	CTFVTQDBNNPXAX-LJQANCHMSA-N	572084	(R)-N-(4-(3-((6-methylquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 49	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572084	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572084&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086790	473133157							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207622	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccncc2n1	InChI=1S/C21H22N6O2/c1-2-19(28)24-16-5-3-14(4-6-16)20(29)27-10-8-17(13-27)25-21-23-11-15-7-9-22-12-18(15)26-21/h3-7,9,11-12,17H,2,8,10,13H2,1H3,(H,24,28)(H,23,25,26)/t17-/m1/s1	DKNAZEYWKWYKJO-QGZVFWFLSA-N	572085	(R)-N-(4-(3-(pyrido[3,4-d]pyrimidin- 2-ylamino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 50	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572085&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086907	473133158							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207625	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(OC)cc2n1	InChI=1S/C23H25N5O3/c1-3-21(29)25-17-7-4-15(5-8-17)22(30)28-11-10-18(14-28)26-23-24-13-16-6-9-19(31-2)12-20(16)27-23/h4-9,12-13,18H,3,10-11,14H2,1-2H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	HRHHBYMFSQGBEX-GOSISDBHSA-N	572086	(R)-N-(4-(3-((7-methoxyquinazolin- 2-yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 51	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572086	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572086&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086820	473133159							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207628	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(cc2n1)S(C)(=O)=O	InChI=1S/C23H25N5O4S/c1-3-21(29)25-17-7-4-15(5-8-17)22(30)28-11-10-18(14-28)26-23-24-13-16-6-9-19(33(2,31)32)12-20(16)27-23/h4-9,12-13,18H,3,10-11,14H2,1-2H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	FSJGFYIBZOXTAU-GOSISDBHSA-N	572087	(R)-N-(4-(3-((7- (methylsulfonyl)quinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 52	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572087	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572087&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086766	473133160							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207631	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(Cl)cc2n1	InChI=1S/C22H22ClN5O2/c1-2-20(29)25-17-7-4-14(5-8-17)21(30)28-10-9-18(13-28)26-22-24-12-15-3-6-16(23)11-19(15)27-22/h3-8,11-12,18H,2,9-10,13H2,1H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	IOZSUUYSURMXEI-GOSISDBHSA-N	572088	(R)-N-(4-(3-((7-methoxyquinazolin- 2-yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 53	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572088	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572088&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086873	473133161							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207634	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(F)cc2n1	InChI=1S/C22H22FN5O2/c1-2-20(29)25-17-7-4-14(5-8-17)21(30)28-10-9-18(13-28)26-22-24-12-15-3-6-16(23)11-19(15)27-22/h3-8,11-12,18H,2,9-10,13H2,1H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	DKIOTQWXLYOBOF-GOSISDBHSA-N	572089	(R)-N-(4-(3-((7-fluoroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 54	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572089	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572089&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086836	473133162							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207637	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(cc2n1)C#N	InChI=1S/C23H22N6O2/c1-2-21(30)26-18-7-5-16(6-8-18)22(31)29-10-9-19(14-29)27-23-25-13-17-4-3-15(12-24)11-20(17)28-23/h3-8,11,13,19H,2,9-10,14H2,1H3,(H,26,30)(H,25,27,28)/t19-/m1/s1	YECFQQVVMJBGDA-LJQANCHMSA-N	572090	(R)-N-(4-(3-((7-cyanoquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 55	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572090&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086739	473133163							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207640	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(cc2n1)C(O)=O	InChI=1S/C23H23N5O4/c1-2-20(29)25-17-7-5-14(6-8-17)21(30)28-10-9-18(13-28)26-23-24-12-16-4-3-15(22(31)32)11-19(16)27-23/h3-8,11-12,18H,2,9-10,13H2,1H3,(H,25,29)(H,31,32)(H,24,26,27)/t18-/m1/s1	UZRHOKXLDQYYHC-GOSISDBHSA-N	572091	(R)-2-((1-(4- propionamidobenzoyl)pyrrolidin-3- yl)amino)quinazoline-7-carboxylic acid::US11447493, Example 56	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572091	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572091&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086729	473133164							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207643	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(cc2n1)C(N)=O	InChI=1S/C23H24N6O3/c1-2-20(30)26-17-7-5-14(6-8-17)22(32)29-10-9-18(13-29)27-23-25-12-16-4-3-15(21(24)31)11-19(16)28-23/h3-8,11-12,18H,2,9-10,13H2,1H3,(H2,24,31)(H,26,30)(H,25,27,28)/t18-/m1/s1	PPWAOTHZSAFCAT-GOSISDBHSA-N	572092	(R)-2-((1-(4- propionamidobenzoyl)pyrrolidin-3- yl)amino)quinazoline-7-carboxamide::US11447493, Example 57	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572092	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572092&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086905	473133165							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207646	CNC(=O)c1ccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc2c1	InChI=1S/C24H24N6O3/c1-3-21(31)27-18-8-6-15(7-9-18)23(33)30-11-10-19(14-30)28-24-26-13-17-5-4-16(22(32)25-2)12-20(17)29-24/h3-9,12-13,19H,1,10-11,14H2,2H3,(H,25,32)(H,27,31)(H,26,28,29)/t19-/m1/s1	FUQXGHBWVRRQHX-LJQANCHMSA-N	572075	(R)-2-((1-(4- acrylamidobenzoyl)pyrrolidin-3- yl)amino)-N-methylquinazoline-7- carboxamide::US11447493, Example 40::US11447493, Example 58	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572075	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572075&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150226933	473133148							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207649	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(cc2n1)C(=O)N(C)C	InChI=1S/C25H28N6O3/c1-4-22(32)27-19-9-7-16(8-10-19)24(34)31-12-11-20(15-31)28-25-26-14-18-6-5-17(13-21(18)29-25)23(33)30(2)3/h5-10,13-14,20H,4,11-12,15H2,1-3H3,(H,27,32)(H,26,28,29)/t20-/m1/s1	IICXTPOQWARWOV-HXUWFJFHSA-N	572094	(R)-N,N-dimethyl-2-((1-(4- propionamidobenzoyl)pyrrolidin-3- yl)amino)quinazoline-7-carboxamide::US11447493, Example 59	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572094	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572094&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086835	473133166							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207652	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(=O)[nH]c2n1			572095	(R)-N-(4-(3-((7-oxo-7,8- dihydropyrido[2,3-d]pyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 60	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572095	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572095&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			165437191	473133167							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207657	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(=O)n(C(C)C)c2n1	InChI=1S/C24H28N6O3/c1-4-20(31)26-18-8-5-16(6-9-18)23(33)29-12-11-19(14-29)27-24-25-13-17-7-10-21(32)30(15(2)3)22(17)28-24/h5-10,13,15,19H,4,11-12,14H2,1-3H3,(H,26,31)(H,25,27,28)/t19-/m1/s1	IHOAWPUMJLGVEZ-LJQANCHMSA-N	572096	(R)-N-(4-(3-((8-isopropyl-7-oxo-7,8- dihydropyrido[2,3-d]pyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 61	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572096&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086890	473133168							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207658	CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccc(=O)n(C(C)C)c2n1	InChI=1S/C24H28N6O3/c1-4-20(31)26-18-8-5-16(6-9-18)23(33)29-12-11-19(14-29)27-24-25-13-17-7-10-21(32)30(15(2)3)22(17)28-24/h5-10,13,15,19H,4,11-12,14H2,1-3H3,(H,26,31)(H,25,27,28)/t19-/m1/s1	IHOAWPUMJLGVEZ-LJQANCHMSA-N	572096	(R)-N-(4-(3-((8-isopropyl-7-oxo-7,8- dihydropyrido[2,3-d]pyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US11447493, Example 61	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572096&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086890	473133168							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207663	Fc1cc(ccc1NC(=O)C=C)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C22H20FN5O2/c1-2-20(29)26-19-8-7-14(11-17(19)23)21(30)28-10-9-16(13-28)25-22-24-12-15-5-3-4-6-18(15)27-22/h2-8,11-12,16H,1,9-10,13H2,(H,26,29)(H,24,25,27)/t16-/m1/s1	GYQGWMAYFQZINJ-MRXNPFEDSA-N	572097	(R)-N-(2-fluoro-4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 62	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572097&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150375655	473133169							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207664	Fc1cc(ccc1NC(=O)C=C)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C22H20FN5O2/c1-2-20(29)26-19-8-7-14(11-17(19)23)21(30)28-10-9-16(13-28)25-22-24-12-15-5-3-4-6-18(15)27-22/h2-8,11-12,16H,1,9-10,13H2,(H,26,29)(H,24,25,27)/t16-/m1/s1	GYQGWMAYFQZINJ-MRXNPFEDSA-N	572097	(R)-N-(2-fluoro-4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 62	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572097	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572097&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150375655	473133169							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207667	F[C@H]1CN(C[C@@H]1Nc1ncc2ccccc2n1)C(=O)c1ccc(NC(=O)C=C)cc1	InChI=1S/C22H20FN5O2/c1-2-20(29)25-16-9-7-14(8-10-16)21(30)28-12-17(23)19(13-28)27-22-24-11-15-5-3-4-6-18(15)26-22/h2-11,17,19H,1,12-13H2,(H,25,29)(H,24,26,27)/t17-,19-/m0/s1	GQFCNTKPAFRBKK-HKUYNNGSSA-N	572098	N-(4-((3S,4S)-3-fluoro-4- (quinazolin-2-ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 63	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572098	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572098&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150333642	473133170							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207670	C=CC(=O)Nc1ccc(cc1)C(=O)N1CC(C1)Nc1ncc2ccccc2n1	InChI=1S/C21H19N5O2/c1-2-19(27)23-16-9-7-14(8-10-16)20(28)26-12-17(13-26)24-21-22-11-15-5-3-4-6-18(15)25-21/h2-11,17H,1,12-13H2,(H,23,27)(H,22,24,25)	OPOLXEPGMNZIEN-UHFFFAOYSA-N	572099	N-(4-(3-(quinazolin-2- ylamino)azetidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 64	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 20000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572099	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572099&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151366654	473133171							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207673	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C25H28N6O2/c1-30(2)14-5-8-23(32)27-20-11-9-18(10-12-20)24(33)31-15-13-21(17-31)28-25-26-16-19-6-3-4-7-22(19)29-25/h3-12,16,21H,13-15,17H2,1-2H3,(H,27,32)(H,26,28,29)/b8-5+/t21-/m1/s1	SXMMHTKZUYOEJX-WKOQKXSESA-N	572100	(R,E)-4-(dimethylamino)-N-(4-(3- (quinazolin-2-ylamino)pyrrolidine-1- carbonyl)phenyl)but-2-enamide::US11447493, Example 65	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572100	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572100&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151924623	473133172							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207676	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C26H30N6O2/c1-31(2)15-6-10-24(33)28-21-13-11-19(12-14-21)25(34)32-16-5-8-22(18-32)29-26-27-17-20-7-3-4-9-23(20)30-26/h3-4,6-7,9-14,17,22H,5,8,15-16,18H2,1-2H3,(H,28,33)(H,27,29,30)/b10-6+/t22-/m1/s1	OOOTWPYQOQWVHB-MOVYNIQHSA-N	572101	(R,E)-4-(dimethylamino)-N-(4-(3- (quinazolin-2-ylamino)piperidine-1- carbonyl)phenyl)but-2-enamide::US11447493, Example 66	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 65000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572101	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572101&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			148803927	473133173							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207681	C=CC(=O)Nc1ccc(cn1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C21H20N6O2/c1-2-19(28)26-18-8-7-15(12-22-18)20(29)27-10-9-16(13-27)24-21-23-11-14-5-3-4-6-17(14)25-21/h2-8,11-12,16H,1,9-10,13H2,(H,22,26,28)(H,23,24,25)/t16-/m1/s1	LRKRQTMUHJKJQW-MRXNPFEDSA-N	572102	(R)-N-(5-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)pyridin-2-yl)acrylamide::US11447493, Example 67	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572102&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086784	473133174							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207682	C=CC(=O)Nc1ccc(cn1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C21H20N6O2/c1-2-19(28)26-18-8-7-15(12-22-18)20(29)27-10-9-16(13-27)24-21-23-11-14-5-3-4-6-17(14)25-21/h2-8,11-12,16H,1,9-10,13H2,(H,22,26,28)(H,23,24,25)/t16-/m1/s1	LRKRQTMUHJKJQW-MRXNPFEDSA-N	572102	(R)-N-(5-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)pyridin-2-yl)acrylamide::US11447493, Example 67	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572102	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572102&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			156086784	473133174							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207685	CN(C)C\C=C\C(=O)Nc1ccc(cc1F)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C25H27FN6O2/c1-31(2)12-5-8-23(33)29-22-10-9-17(14-20(22)26)24(34)32-13-11-19(16-32)28-25-27-15-18-6-3-4-7-21(18)30-25/h3-10,14-15,19H,11-13,16H2,1-2H3,(H,29,33)(H,27,28,30)/b8-5+/t19-/m1/s1	FALPBHNCTNGUFH-MTCRFPMVSA-N	572103	(R,E)-4-(dimethylamino)-N-(2- fluoro-4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)but-2-enamide::US11447493, Example 68	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572103	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572103&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150127118	473133175							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207688	Fc1ccc2nc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)c(F)c3)ncc2c1	InChI=1S/C22H19F2N5O2/c1-2-20(30)27-19-5-3-13(10-17(19)24)21(31)29-8-7-16(12-29)26-22-25-11-14-9-15(23)4-6-18(14)28-22/h2-6,9-11,16H,1,7-8,12H2,(H,27,30)(H,25,26,28)/t16-/m1/s1	UINMSSDBWWHFFC-MRXNPFEDSA-N	572104	(R)-N-(2-fluoro-4-(3-((6- fluoroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 69	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572104	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572104&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152010217	473133176							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207691	O=C(Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1)C#C	InChI=1S/C22H19N5O2/c1-2-20(28)24-17-9-7-15(8-10-17)21(29)27-12-11-18(14-27)25-22-23-13-16-5-3-4-6-19(16)26-22/h1,3-10,13,18H,11-12,14H2,(H,24,28)(H,23,25,26)/t18-/m1/s1	PWEDJMTYYMURIC-GOSISDBHSA-N	572105	(R)-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)propiolamide::US11447493, Example 70	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<100							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572105	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572105&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151529510	473133177							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207694	COc1cc(ccc1NC(=O)C=C)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H23N5O3/c1-3-21(29)26-19-9-8-15(12-20(19)31-2)22(30)28-11-10-17(14-28)25-23-24-13-16-6-4-5-7-18(16)27-23/h3-9,12-13,17H,1,10-11,14H2,2H3,(H,26,29)(H,24,25,27)/t17-/m1/s1	YQKZZMRZIVDLDV-QGZVFWFLSA-N	572106	(R)-N-(2-methoxy-4-(3-(quinazolin- 2-ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 71	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572106&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			149406729	473133178							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207699	Cc1cc(ccc1NC(=O)C=C)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H23N5O2/c1-3-21(29)26-19-9-8-16(12-15(19)2)22(30)28-11-10-18(14-28)25-23-24-13-17-6-4-5-7-20(17)27-23/h3-9,12-13,18H,1,10-11,14H2,2H3,(H,26,29)(H,24,25,27)/t18-/m1/s1	IYJULXBZNSIWSN-GOSISDBHSA-N	572107	(R)-N-(2-methyl-4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 72	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572107&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			148008738	473133179							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207700	Cc1cc(ccc1NC(=O)C=C)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H23N5O2/c1-3-21(29)26-19-9-8-16(12-15(19)2)22(30)28-11-10-18(14-28)25-23-24-13-17-6-4-5-7-20(17)27-23/h3-9,12-13,18H,1,10-11,14H2,2H3,(H,26,29)(H,24,25,27)/t18-/m1/s1	IYJULXBZNSIWSN-GOSISDBHSA-N	572107	(R)-N-(2-methyl-4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 72	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572107&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			148008738	473133179							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207703	COc1cc(NC(=O)C=C)ccc1C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H23N5O3/c1-3-21(29)25-16-8-9-18(20(12-16)31-2)22(30)28-11-10-17(14-28)26-23-24-13-15-6-4-5-7-19(15)27-23/h3-9,12-13,17H,1,10-11,14H2,2H3,(H,25,29)(H,24,26,27)/t17-/m1/s1	IXRHEVMMVUNFRH-QGZVFWFLSA-N	572108	N-{3-Methoxy-4-[3-(quinazolin-2- ylamino)-pyrrolidine-1-carbonyl]- phenyl}-acrylamide::US11447493, Example 73	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572108&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150629950	473133180							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207708	CN(C(=O)C=C)c1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H23N5O2/c1-3-21(29)27(2)19-10-8-16(9-11-19)22(30)28-13-12-18(15-28)25-23-24-14-17-6-4-5-7-20(17)26-23/h3-11,14,18H,1,12-13,15H2,2H3,(H,24,25,26)/t18-/m1/s1	ZZVZQPYKDRXMAS-GOSISDBHSA-N	572109	(R)-N-methyl-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 74	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572109&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152742276	473133181							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207709	CN(C(=O)C=C)c1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H23N5O2/c1-3-21(29)27(2)19-10-8-16(9-11-19)22(30)28-13-12-18(15-28)25-23-24-14-17-6-4-5-7-20(17)26-23/h3-11,14,18H,1,12-13,15H2,2H3,(H,24,25,26)/t18-/m1/s1	ZZVZQPYKDRXMAS-GOSISDBHSA-N	572109	(R)-N-methyl-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 74	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572109&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152742276	473133181							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207712	Cc1cc(cc(F)c1NC(=O)C=C)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H22FN5O2/c1-3-20(30)28-21-14(2)10-16(11-18(21)24)22(31)29-9-8-17(13-29)26-23-25-12-15-6-4-5-7-19(15)27-23/h3-7,10-12,17H,1,8-9,13H2,2H3,(H,28,30)(H,25,26,27)/t17-/m1/s1	DRGGVGJKEXYMTJ-QGZVFWFLSA-N	572110	(R)-N-(2-fluoro-6-methyl-4-(3- (quinazolin-2-ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 75	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 20000							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572110&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150080961	473133182							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207715	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2cc(F)ccc2n1	InChI=1S/C25H27FN6O2/c1-31(2)12-3-4-23(33)28-20-8-5-17(6-9-20)24(34)32-13-11-21(16-32)29-25-27-15-18-14-19(26)7-10-22(18)30-25/h3-10,14-15,21H,11-13,16H2,1-2H3,(H,28,33)(H,27,29,30)/b4-3+/t21-/m1/s1	MJOVPABKFQFAHK-YEFOHOTDSA-N	572111	(R,E)-4-(dimethylamino)-N-(4-(3- ((6-fluoroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)but-2-enamide::US11447493, Example 76	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572111&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151078320	473133183							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207718	CC#CC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H21N5O2/c1-2-5-21(29)25-18-10-8-16(9-11-18)22(30)28-13-12-19(15-28)26-23-24-14-17-6-3-4-7-20(17)27-23/h3-4,6-11,14,19H,12-13,15H2,1H3,(H,25,29)(H,24,26,27)/t19-/m1/s1	OGMQDTCYGLFVAY-LJQANCHMSA-N	572112	(R)-N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)but-2-ynamide::US11447493, Example 77	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572112&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151321222	473133184							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207721	Cc1cc(NC(=O)C=C)ccc1C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C23H23N5O2/c1-3-21(29)25-17-8-9-19(15(2)12-17)22(30)28-11-10-18(14-28)26-23-24-13-16-6-4-5-7-20(16)27-23/h3-9,12-13,18H,1,10-11,14H2,2H3,(H,25,29)(H,24,26,27)/t18-/m1/s1	SNEOQNDRTVGPGR-GOSISDBHSA-N	572113	(R)-N-(3-methyl-4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 78	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572113&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151873468	473133185							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207724	C=CC(=O)N1CCCc2cc(ccc12)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C25H25N5O2/c1-2-23(31)30-12-5-7-17-14-18(9-10-22(17)30)24(32)29-13-11-20(16-29)27-25-26-15-19-6-3-4-8-21(19)28-25/h2-4,6,8-10,14-15,20H,1,5,7,11-13,16H2,(H,26,27,28)/t20-/m1/s1	MHPRDIRNBCRGKO-HXUWFJFHSA-N	572114	(R)-1-(6-(3-(quinazolin-2- ylamino)pyrrolidine-1-carbonyl)-3,4- dihydroquinolin-1(2H)-yl)prop-2-en- 1-one::US11447493, Example 79	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572114&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			148485061	473133186							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207727	C=CC(=O)N1CCOc2cc(ccc12)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C24H23N5O3/c1-2-22(30)29-11-12-32-21-13-16(7-8-20(21)29)23(31)28-10-9-18(15-28)26-24-25-14-17-5-3-4-6-19(17)27-24/h2-8,13-14,18H,1,9-12,15H2,(H,25,26,27)/t18-/m1/s1	ORZWXCBRFNEYDM-GOSISDBHSA-N	572115	(R)-1-(7-(3-(quinazolin-2- ylamino)pyrrolidine-1-carbonyl)-2H- benzo[b][1,4]oxazin-4(3H)-yl)prop- 2-en-1-one::US11447493, Example 80	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572115&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151378995	473133187							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207730	COc1cc(ccc1NC(=O)\C=C\CN(C)C)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C26H30N6O3/c1-31(2)13-6-9-24(33)29-22-11-10-18(15-23(22)35-3)25(34)32-14-12-20(17-32)28-26-27-16-19-7-4-5-8-21(19)30-26/h4-11,15-16,20H,12-14,17H2,1-3H3,(H,29,33)(H,27,28,30)/b9-6+/t20-/m1/s1	DLVVFKMWFVZWDD-AQDCRGGLSA-N	572116	(R,E)-4-(dimethylamino)-N-(2- methoxy-4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)but-2-enamide::US11447493, Example 81	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572116&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150053771	473133188							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207733	CN(C)C\C=C\C(=O)Nc1ccc(cc1Cl)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C25H27ClN6O2/c1-31(2)12-5-8-23(33)29-22-10-9-17(14-20(22)26)24(34)32-13-11-19(16-32)28-25-27-15-18-6-3-4-7-21(18)30-25/h3-10,14-15,19H,11-13,16H2,1-2H3,(H,29,33)(H,27,28,30)/b8-5+/t19-/m1/s1	IUJVWZRIKASHNS-MTCRFPMVSA-N	572117	(R,E)-N-(2-chloro-4-(3-(quinazolin- 2-ylamino)pyrrolidine-1- carbonyl)phenyl)-4- (dimethylamino)but-2-enamide::US11447493, Example 82	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572117&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			147987394	473133189							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207736	CN(C)C\C=C\C(=O)Nc1ccc(cc1C)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C26H30N6O2/c1-18-15-19(10-11-22(18)29-24(33)9-6-13-31(2)3)25(34)32-14-12-21(17-32)28-26-27-16-20-7-4-5-8-23(20)30-26/h4-11,15-16,21H,12-14,17H2,1-3H3,(H,29,33)(H,27,28,30)/b9-6+/t21-/m1/s1	UQDLBEGORWSOQS-VHTFYLNKSA-N	572118	(R,E)-4-(dimethylamino)-N-(2- methyl-4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)but-2-enamide::US11447493, Example 83	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572118&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152048311	473133190							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207739	CN(C)C\C=C\C(=O)N1CCOc2cc(ccc12)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C27H30N6O3/c1-31(2)12-5-8-25(34)33-14-15-36-24-16-19(9-10-23(24)33)26(35)32-13-11-21(18-32)29-27-28-17-20-6-3-4-7-22(20)30-27/h3-10,16-17,21H,11-15,18H2,1-2H3,(H,28,29,30)/b8-5+/t21-/m1/s1	JMVIDMZVTXZHKA-WKOQKXSESA-N	572119	(R,E)-4-(dimethylamino)-1-(7-(3- (quinazolin-2-ylamino)pyrrolidine-1- carbonyl)-2H-benzo[b][1,4]oxazin- 4(3H)-yl)but-2-en-1-one::US11447493, Example 84	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572119&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150705792	473133191							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207742	COc1cc(NC(=O)\C=C\CN(C)C)ccc1C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C26H30N6O3/c1-31(2)13-6-9-24(33)28-19-10-11-21(23(15-19)35-3)25(34)32-14-12-20(17-32)29-26-27-16-18-7-4-5-8-22(18)30-26/h4-11,15-16,20H,12-14,17H2,1-3H3,(H,28,33)(H,27,29,30)/b9-6+/t20-/m1/s1	SIGKFKBFXQQJJH-AQDCRGGLSA-N	572120	4-Dimethylamino-but-2-enoic acid {3-methoxy-4-[3-(quinazolin-2- ylamino)-pyrrolidine-1-carbonyl]- phenyl}-amide::US11447493, Example 85	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572120&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151848932	473133192							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207745	CN(C)C\C=C\C(=O)N(C)c1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C26H30N6O2/c1-30(2)15-6-9-24(33)31(3)22-12-10-19(11-13-22)25(34)32-16-14-21(18-32)28-26-27-17-20-7-4-5-8-23(20)29-26/h4-13,17,21H,14-16,18H2,1-3H3,(H,27,28,29)/b9-6+/t21-/m1/s1	LNYCRXZEMSCWFG-VHTFYLNKSA-N	572121	(R,E)-4-(dimethylamino)-N-methyl- N-(4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)but-2-enamide::US11447493, Example 86	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572121&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			148379919	473133193							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207748	C=CC(=O)Nc1cccc(c1)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C22H21N5O2/c1-2-20(28)24-17-8-5-7-15(12-17)21(29)27-11-10-18(14-27)25-22-23-13-16-6-3-4-9-19(16)26-22/h2-9,12-13,18H,1,10-11,14H2,(H,24,28)(H,23,25,26)/t18-/m1/s1	XRNXDWRXNVCTGN-GOSISDBHSA-N	572122	(R)-N-(3-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 87	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572122&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			152441377	473133194							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207753	Clc1cc(ccc1NC(=O)C=C)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C22H20ClN5O2/c1-2-20(29)26-19-8-7-14(11-17(19)23)21(30)28-10-9-16(13-28)25-22-24-12-15-5-3-4-6-18(15)27-22/h2-8,11-12,16H,1,9-10,13H2,(H,26,29)(H,24,25,27)/t16-/m1/s1	ONRGJWZQIHEWQH-MRXNPFEDSA-N	572123	(R)-N-(2-chloro-4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 88	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572123&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151356994	473133195							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207754	Clc1cc(ccc1NC(=O)C=C)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C22H20ClN5O2/c1-2-20(29)26-19-8-7-14(11-17(19)23)21(30)28-10-9-16(13-28)25-22-24-12-15-5-3-4-6-18(15)27-22/h2-8,11-12,16H,1,9-10,13H2,(H,26,29)(H,24,25,27)/t16-/m1/s1	ONRGJWZQIHEWQH-MRXNPFEDSA-N	572123	(R)-N-(2-chloro-4-(3-(quinazolin-2- ylamino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 88	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806825	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572123&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			151356994	473133195							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207757	CN(C)C\C=C\C(=O)N1CCCc2cc(ccc12)C(=O)N1CC[C@H](C1)Nc1ncc2ccccc2n1	InChI=1S/C28H32N6O2/c1-32(2)14-6-10-26(35)34-15-5-8-20-17-21(11-12-25(20)34)27(36)33-16-13-23(19-33)30-28-29-18-22-7-3-4-9-24(22)31-28/h3-4,6-7,9-12,17-18,23H,5,8,13-16,19H2,1-2H3,(H,29,30,31)/b10-6+/t23-/m1/s1	RVHAEPLNTRENOO-PQCQUMGKSA-N	572124	(R,E)-4-(dimethylamino)-1-(6-(3- (quinazolin-2-ylamino)pyrrolidine-1- carbonyl)-3,4-dihydroquinolin- 1(2H)-yl)but-2-en-1-one::US11447493, Example 89	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572124&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			146788124	473133196							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1207760	Fc1cccc2cnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)nc12	InChI=1S/C22H20FN5O2/c1-2-19(29)25-16-8-6-14(7-9-16)21(30)28-11-10-17(13-28)26-22-24-12-15-4-3-5-18(23)20(15)27-22/h2-9,12,17H,1,10-11,13H2,(H,25,29)(H,24,26,27)/t17-/m1/s1	ILLVNLODYLPPIC-QGZVFWFLSA-N	572125	(R)-N-(4-(3-((8-fluoroquinazolin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US11447493, Example 90	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 5500							US Patent		10.7270/Q2CF9TBB		aid1806824	US11447493	Kanouni, T; Arnold, L; Kaldor, SW; Murphy, EA	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=572125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=572125&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			150569130	473133197							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51443590	CCN(CC)c1cnc2ccc(cc2n1)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F	InChI=1S/C25H28FN9/c1-3-34(4-2)23-16-28-20-7-5-17(13-21(20)31-23)24-19(26)15-30-25(33-24)32-22-8-6-18(14-29-22)35-11-9-27-10-12-35/h5-8,13-16,27H,3-4,9-12H2,1-2H3,(H,29,30,32,33)	SKOICOFQIQHEPE-UHFFFAOYSA-N	50583189	CHEMBL5079648	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 393							ChEMBL	10.1021/acs.jmedchem.1c02019	10.7270/Q2D222HB	34958208			Yuan, K; Ji, M; Xie, S; Qiu, Z; Chen, W; Min, W; Xia, F; Zheng, M; Wang, X; Li, J; Hou, Y; Kuang, W; Wang, L; Gu, W; Li, Z; Yang, P	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50583189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50583189&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163196279	476028194							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227243	CC(C)c1cnn2c(NCc3ccccc3N(C)C)cc(OC3CCN(C)CC3)nc12	InChI=1S/C24H34N6O/c1-17(2)20-16-26-30-22(25-15-18-8-6-7-9-21(18)28(3)4)14-23(27-24(20)30)31-19-10-12-29(5)13-11-19/h6-9,14,16-17,19,25H,10-13,15H2,1-5H3	JCOZOIXEEPDWEC-UHFFFAOYSA-N	581943	WO2023001061, Example 1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581943	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581943&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594722	475727758							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227244	CC(C)c1cnn2c(NCC3CCCN3C)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C21H35N7O/c1-14(2)17-12-25-28-20(24-11-16-5-4-8-27(16)3)9-19(26-21(17)28)23-10-15-6-7-22-13-18(15)29/h9,12,14-16,18,22,24,29H,4-8,10-11,13H2,1-3H3,(H,23,26)/t15-,16?,18+/m1/s1	QQLSIJHLYVKUPE-AGPBCMBSSA-N	581947	WO2023001061, Example 2	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581947	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581947&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594725	475727762							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227245	CC(C)c1cnn2c(NCc3nc4cc(ccc4s3)N(C)C)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C25H34N8OS/c1-15(2)18-12-29-33-23(10-22(31-25(18)33)27-11-16-7-8-26-13-20(16)34)28-14-24-30-19-9-17(32(3)4)5-6-21(19)35-24/h5-6,9-10,12,15-16,20,26,28,34H,7-8,11,13-14H2,1-4H3,(H,27,31)/t16-,20+/m1/s1	NXRKFXLYXYGWNQ-UZLBHIALSA-N	581954	WO2023001061, Example 4	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581954	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581954&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594732	475727769							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227246	CC(C)c1cnn2c(NCc3ccc4cccc(N(C)C)c4n3)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C27H36N8O/c1-17(2)21-15-31-35-25(12-24(33-27(21)35)29-13-19-10-11-28-16-23(19)36)30-14-20-9-8-18-6-5-7-22(34(3)4)26(18)32-20/h5-9,12,15,17,19,23,28,30,36H,10-11,13-14,16H2,1-4H3,(H,29,33)/t19-,23+/m1/s1	SKBSWOBKDUUYNC-XXBNENTESA-N	581955	WO2023001061, Example 5	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581955	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581955&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594733	475727770							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227247	CC(C)c1cnn2c(NCc3ccnn3C)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C20H30N8O/c1-13(2)16-11-25-28-19(23-10-15-5-7-24-27(15)3)8-18(26-20(16)28)22-9-14-4-6-21-12-17(14)29/h5,7-8,11,13-14,17,21,23,29H,4,6,9-10,12H2,1-3H3,(H,22,26)/t14-,17+/m1/s1	ZLSKNJNVHQBNSQ-PBHICJAKSA-N	581956	WO2023001061, Example 6	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581956	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581956&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594734	475727771							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227248	CC(C)c1cnn2c(NCc3ccnn3C)cc(OC3CCN(C)CC3)nc12	InChI=1S/C20H29N7O/c1-14(2)17-13-23-27-18(21-12-15-5-8-22-26(15)4)11-19(24-20(17)27)28-16-6-9-25(3)10-7-16/h5,8,11,13-14,16,21H,6-7,9-10,12H2,1-4H3	IPIBQKDBYRSOMN-UHFFFAOYSA-N	581957	WO2023001061, Example 7	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581957&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594735	475727772							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227249	CC(C)c1cnn2c(NCC3CCCN3C)cc(OC3CCN(C)CC3)nc12	InChI=1S/C21H34N6O/c1-15(2)18-14-23-27-19(22-13-16-6-5-9-26(16)4)12-20(24-21(18)27)28-17-7-10-25(3)11-8-17/h12,14-17,22H,5-11,13H2,1-4H3	AZQXMHJPBLALOY-UHFFFAOYSA-N	581958	WO2023001061, Example 8	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<500							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581958	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581958&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594736	475727773							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227250	CC(C)c1cnn2c(NCc3ccn[nH]3)cc(NC[C@H]3CCNC[C@@H]3O)nc12			581959	WO2023001061, Example 9	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581959&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594737	475727774							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227251	CC(C)c1cnn2c(NCc3ccnn3C(C)C)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C22H34N8O/c1-14(2)18-12-27-30-21(25-11-17-6-8-26-29(17)15(3)4)9-20(28-22(18)30)24-10-16-5-7-23-13-19(16)31/h6,8-9,12,14-16,19,23,25,31H,5,7,10-11,13H2,1-4H3,(H,24,28)/t16-,19+/m1/s1	KGZCIDNWKNXDCC-APWZRJJASA-N	581960	WO2023001061, Example 10	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581960	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581960&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594738	475727775							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227252	CC(C)c1cnn2c(NCc3ccnn3C3CC3)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C22H32N8O/c1-14(2)18-12-27-30-21(25-11-17-6-8-26-29(17)16-3-4-16)9-20(28-22(18)30)24-10-15-5-7-23-13-19(15)31/h6,8-9,12,14-16,19,23,25,31H,3-5,7,10-11,13H2,1-2H3,(H,24,28)/t15-,19+/m1/s1	ZHXAKMMAJQMWOA-BEFAXECRSA-N	581961	WO2023001061, Example 11	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581961	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581961&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594739	475727776							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227253	CC(C)c1cnn2c(NCc3cncn3C)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C20H30N8O/c1-13(2)16-10-25-28-19(24-9-15-8-22-12-27(15)3)6-18(26-20(16)28)23-7-14-4-5-21-11-17(14)29/h6,8,10,12-14,17,21,24,29H,4-5,7,9,11H2,1-3H3,(H,23,26)/t14-,17+/m1/s1	FXIPVFNUEHLMKQ-PBHICJAKSA-N	581962	WO2023001061, Example 13	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581962	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581962&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594740	475727777							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227254	CC(C)c1cnn2c(NCc3nccn3C)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C20H30N8O/c1-13(2)15-10-25-28-18(24-12-19-22-6-7-27(19)3)8-17(26-20(15)28)23-9-14-4-5-21-11-16(14)29/h6-8,10,13-14,16,21,24,29H,4-5,9,11-12H2,1-3H3,(H,23,26)/t14-,16+/m1/s1	ZSNYHSFUFYNDDV-ZBFHGGJFSA-N	581963	WO2023001061, Example 14	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581963	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581963&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594741	475727778							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227255	CC(C)c1cnn2c(NCc3cccnc3N(C)C)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C23H34N8O/c1-15(2)18-13-28-31-21(27-12-17-6-5-8-25-22(17)30(3)4)10-20(29-23(18)31)26-11-16-7-9-24-14-19(16)32/h5-6,8,10,13,15-16,19,24,27,32H,7,9,11-12,14H2,1-4H3,(H,26,29)/t16-,19+/m1/s1	OIBBCAGCMFNITD-APWZRJJASA-N	581964	WO2023001061, Example 15	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581964&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594742	475727779							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227256	CC(C)c1cnn2c(NCC3CCCN3C)nc(OC3CCN(C)CC3)nc12	InChI=1S/C20H33N7O/c1-14(2)17-13-22-27-18(17)23-20(28-16-7-10-25(3)11-8-16)24-19(27)21-12-15-6-5-9-26(15)4/h13-16H,5-12H2,1-4H3,(H,21,23,24)	XCILXLUBNUIVJH-UHFFFAOYSA-N	581965	WO2023001061, Example 23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<500							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581965	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581965&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594743	475727780							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227257	CC(C)c1cnn2c(NCc3ccnn3C)nc(OC3CCN(C)CC3)nc12	InChI=1S/C19H28N8O/c1-13(2)16-12-22-27-17(16)23-19(28-15-6-9-25(3)10-7-15)24-18(27)20-11-14-5-8-21-26(14)4/h5,8,12-13,15H,6-7,9-11H2,1-4H3,(H,20,23,24)	BAWBHLYXTNQSAV-UHFFFAOYSA-N	581966	WO2023001061, Example 26	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581966	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581966&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594744	475727781							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227258	CC(C)c1cnn2c(NCc3ccc4cccc(N(C)C)c4n3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C26H34N8O/c1-17(2)21-16-28-34-24(21)30-26(35-20-11-13-33(5)14-12-20)31-25(34)27-15-19-10-9-18-7-6-8-22(32(3)4)23(18)29-19/h6-10,16-17,20H,11-15H2,1-5H3,(H,27,30,31)	JLDMXPNTGLHCFR-UHFFFAOYSA-N	581967	WO2023001061, Example 27	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581967	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581967&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594745	475727782							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227259	CC(C)c1cnn2c(NCc3cc(C)nn3C3CC3)nc(OC3CCN(C)CC3)nc12	InChI=1S/C22H32N8O/c1-14(2)19-13-24-30-20(19)25-22(31-18-7-9-28(4)10-8-18)26-21(30)23-12-17-11-15(3)27-29(17)16-5-6-16/h11,13-14,16,18H,5-10,12H2,1-4H3,(H,23,25,26)	PXZMIYCQGFOFCW-UHFFFAOYSA-N	581968	WO2023001061, Example 28	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581968	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581968&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594746	475727783							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227260	CC(C)c1cnn2c(NCc3ccn(C)n3)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C20H30N8O/c1-13(2)16-11-24-28-19(23-10-15-5-7-27(3)26-15)8-18(25-20(16)28)22-9-14-4-6-21-12-17(14)29/h5,7-8,11,13-14,17,21,23,29H,4,6,9-10,12H2,1-3H3,(H,22,25)/t14-,17+/m1/s1	GZLCFVUKWFMZJJ-PBHICJAKSA-N	581969	WO2023001061, Example 29	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581969	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581969&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594747	475727784							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227261	CC(C)c1cnn2c(NCc3nc4ccccc4s3)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C23H29N7OS/c1-14(2)16-11-27-30-21(26-13-22-28-17-5-3-4-6-19(17)32-22)9-20(29-23(16)30)25-10-15-7-8-24-12-18(15)31/h3-6,9,11,14-15,18,24,26,31H,7-8,10,12-13H2,1-2H3,(H,25,29)/t15-,18+/m1/s1	GJGABQBOXPDTRV-QAPCUYQASA-N	581970	WO2023001061, Example 30	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581970	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581970&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594748	475727785							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227262	CC(C)c1cnn2c(NCc3nccs3)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C19H27N7OS/c1-12(2)14-9-24-26-17(23-11-18-21-5-6-28-18)7-16(25-19(14)26)22-8-13-3-4-20-10-15(13)27/h5-7,9,12-13,15,20,23,27H,3-4,8,10-11H2,1-2H3,(H,22,25)/t13-,15+/m1/s1	CEZLTPZJLLWBSJ-HIFRSBDPSA-N	581971	WO2023001061, Example 31	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581971	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581971&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594749	475727786							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227263	CC(C)c1cnn2c(NCc3nn(C)c4ccccc34)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C24H32N8O/c1-15(2)18-12-28-32-23(27-13-19-17-6-4-5-7-20(17)31(3)30-19)10-22(29-24(18)32)26-11-16-8-9-25-14-21(16)33/h4-7,10,12,15-16,21,25,27,33H,8-9,11,13-14H2,1-3H3,(H,26,29)/t16-,21+/m1/s1	WGGDKILKZYKXPS-IERDGZPVSA-N	581973	WO2023001061, Example 35	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581973	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581973&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594750	475727788							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227264	CC(C)c1cnn2c(NCc3nc4ccccc4n3C)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C24H32N8O/c1-15(2)17-12-28-32-22(27-14-23-29-18-6-4-5-7-19(18)31(23)3)10-21(30-24(17)32)26-11-16-8-9-25-13-20(16)33/h4-7,10,12,15-16,20,25,27,33H,8-9,11,13-14H2,1-3H3,(H,26,30)/t16-,20+/m1/s1	MFYWLMLPDYRLLS-UZLBHIALSA-N	581974	WO2023001061, Example 36	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581974	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581974&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594751	475727789							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227265	CC(C)c1cnn2c(NCc3nc4cc(ccc4s3)C(F)(F)F)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C24H28F3N7OS/c1-13(2)16-10-31-34-21(8-20(33-23(16)34)29-9-14-5-6-28-11-18(14)35)30-12-22-32-17-7-15(24(25,26)27)3-4-19(17)36-22/h3-4,7-8,10,13-14,18,28,30,35H,5-6,9,11-12H2,1-2H3,(H,29,33)/t14-,18+/m1/s1	YGDUFUCOZYWMAK-KDOFPFPSSA-N	581975	WO2023001061, Example 38	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581975&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594752	475727790							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227266	CC(C)c1cnn2c(NCc3nc4cc(Cl)ccc4s3)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C23H28ClN7OS/c1-13(2)16-10-28-31-21(27-12-22-29-17-7-15(24)3-4-19(17)33-22)8-20(30-23(16)31)26-9-14-5-6-25-11-18(14)32/h3-4,7-8,10,13-14,18,25,27,32H,5-6,9,11-12H2,1-2H3,(H,26,30)/t14-,18+/m1/s1	RKRKSRIBWGBMJP-KDOFPFPSSA-N	581976	WO2023001061, Example 39	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581976&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594753	475727791							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1227267	CC(C)c1cnn2c(NCc3nc(cs3)C3CC3)cc(NC[C@H]3CCNC[C@@H]3O)nc12	InChI=1S/C22H31N7OS/c1-13(2)16-9-26-29-20(25-11-21-27-17(12-31-21)14-3-4-14)7-19(28-22(16)29)24-8-15-5-6-23-10-18(15)30/h7,9,12-15,18,23,25,30H,3-6,8,10-11H2,1-2H3,(H,24,28)/t15-,18+/m1/s1	JPYDXXRXVSWIEP-QAPCUYQASA-N	581977	WO2023001061, Example 48	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							WIPO		10.7270/Q2736VR9			WO2023001061	Ying, H; Dapeng, L; Yu, W; Zhiyu, Y; Huajun, L	JINGRUI BIOPHARMA CO., LTD.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=581977	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=581977&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166594754	475727792							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1303671	COCc1cc(C(=O)Nc2cc([nH]n2)[C@H]2CC[C@H](C2)OC(=O)NC(C)C)n(C)n1			498185	US11014911, Example 13::US11718603, Example 13	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 177								US Patent					US11718603	Behenna, DC; Freeman-Cook, KD; Hoffman, RL; Nagata, A; Ninkovic, S; Sutton, SC	PFIZER INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=498185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=498185&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			154616422	459071144							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1303675	Cc1cc(CC(=O)Nc2cc([nH]n2)[C@H]2CC[C@H](C2)OC(=O)NC2(C)CC2)on1			498187	US11014911, Example 15::US11718603, Example 15	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens	 6.30								US Patent					US11718603	Behenna, DC; Freeman-Cook, KD; Hoffman, RL; Nagata, A; Ninkovic, S; Sutton, SC	PFIZER INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=498187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=498187&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			154616850	459071146							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450887	OCc1ccn(n1)-c1ccc(Nc2cc3nc(OC4CCNCC4)ccc3cn2)c(F)c1	InChI=1S/C23H23FN6O2/c24-19-11-17(30-10-7-16(14-31)29-30)2-3-20(19)27-22-12-21-15(13-26-22)1-4-23(28-21)32-18-5-8-25-9-6-18/h1-4,7,10-13,18,25,31H,5-6,8-9,14H2,(H,26,27)	DSHAIQLEQCKJIR-UHFFFAOYSA-N	50585749	CHEMBL5088480	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 87							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585749	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585749&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	65L	7VDP,7VDU	71766886	476021836							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450888	CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(ccc3F)N3CCOCC3)cc2n1	InChI=1S/C26H32FN5O2/c1-26(33,19-7-9-31(2)10-8-19)24-6-3-18-17-28-25(16-22(18)29-24)30-23-15-20(4-5-21(23)27)32-11-13-34-14-12-32/h3-6,15-17,19,33H,7-14H2,1-2H3,(H,28,30)/t26-/m1/s1	LUWQTRGZKXLDSO-AREMUKBSSA-N	50585766	CHEMBL5080866	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 73							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585766	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585766&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166627311	476021853							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450889	CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(ccc3F)N3CCN(CC3)C(C)=O)cc2n1	InChI=1S/C28H35FN6O2/c1-19(36)34-12-14-35(15-13-34)22-5-6-23(29)25(16-22)32-27-17-24-20(18-30-27)4-7-26(31-24)28(2,37)21-8-10-33(3)11-9-21/h4-7,16-18,21,37H,8-15H2,1-3H3,(H,30,32)/t28-/m1/s1	BXQKMGAINGBZAW-MUUNZHRXSA-N	50585767	CHEMBL5079342	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 334							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585767	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585767&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166628065	476021854							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450890	CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(ncc3F)N3CCOCC3)cc2n1	InChI=1S/C25H31FN6O2/c1-25(33,18-5-7-31(2)8-6-18)22-4-3-17-15-27-23(13-20(17)29-22)30-21-14-24(28-16-19(21)26)32-9-11-34-12-10-32/h3-4,13-16,18,33H,5-12H2,1-2H3,(H,27,28,30)/t25-/m1/s1	KFRGPUFONMCXQI-RUZDIDTESA-N	50585771	CHEMBL5078192	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 78							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585771	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585771&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166628927	476021858							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450891	CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(N4CCOCC4)c(cc3F)C#N)cc2n1	InChI=1S/C27H31FN6O2/c1-27(35,20-5-7-33(2)8-6-20)25-4-3-18-17-30-26(15-22(18)31-25)32-23-14-24(19(16-29)13-21(23)28)34-9-11-36-12-10-34/h3-4,13-15,17,20,35H,5-12H2,1-2H3,(H,30,32)/t27-/m1/s1	ODDUUXAHBDCKIJ-HHHXNRCGSA-N	50585772	CHEMBL5080566	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 171							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585772&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	61U	7VDS	162640251	476021859							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450892	CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(ncc3F)N3CCCC3)cc2n1	InChI=1S/C25H31FN6O/c1-25(33,18-7-11-31(2)12-8-18)22-6-5-17-15-27-23(13-20(17)29-22)30-21-14-24(28-16-19(21)26)32-9-3-4-10-32/h5-6,13-16,18,33H,3-4,7-12H2,1-2H3,(H,27,28,30)/t25-/m1/s1	HUNWQLBOLVYRMW-RUZDIDTESA-N	50585775	CHEMBL5091792	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 96							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585775	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585775&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166631779	476021862							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450893	CC(C)Nc1cc(Nc2cc3nc(ccc3cn2)[C@](C)(O)C2CCN(C)CC2)c(F)cn1	InChI=1S/C24H31FN6O/c1-15(2)28-22-12-20(18(25)14-27-22)30-23-11-19-16(13-26-23)5-6-21(29-19)24(3,32)17-7-9-31(4)10-8-17/h5-6,11-15,17,32H,7-10H2,1-4H3,(H2,26,27,28,30)/t24-/m1/s1	UZQXPHDZFUAMQS-XMMPIXPASA-N	50585776	CHEMBL5080123	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 784							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585776	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585776&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166627570	476021863							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450894	CC(C)Oc1cc(Nc2cc3nc(ccc3cn2)[C@](C)(O)C2CCN(C)CC2)c(F)cn1	InChI=1S/C24H30FN5O2/c1-15(2)32-23-12-20(18(25)14-27-23)29-22-11-19-16(13-26-22)5-6-21(28-19)24(3,31)17-7-9-30(4)10-8-17/h5-6,11-15,17,31H,7-10H2,1-4H3,(H,26,27,29)/t24-/m1/s1	WLPDYLPFPWPYBC-XMMPIXPASA-N	50585777	CHEMBL5083778	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 362							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585777	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585777&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166630123	476021864							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450895	CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(OC4CCC4)ncc3F)cc2n1	InChI=1S/C25H30FN5O2/c1-25(32,17-8-10-31(2)11-9-17)22-7-6-16-14-27-23(12-20(16)29-22)30-21-13-24(28-15-19(21)26)33-18-4-3-5-18/h6-7,12-15,17-18,32H,3-5,8-11H2,1-2H3,(H,27,28,30)/t25-/m1/s1	CLCKDDAPJRHFEN-RUZDIDTESA-N	50585778	CHEMBL5084882	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 729							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585778	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585778&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166634189	476021865							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450896	CCc1cc(Nc2cc3nc(ccc3cn2)[C@](C)(O)C2CCN(C)CC2)c(F)cn1	InChI=1S/C23H28FN5O/c1-4-17-11-20(18(24)14-25-17)28-22-12-19-15(13-26-22)5-6-21(27-19)23(2,30)16-7-9-29(3)10-8-16/h5-6,11-14,16,30H,4,7-10H2,1-3H3,(H,25,26,28)/t23-/m1/s1	QXVWBJROURLRIW-HSZRJFAPSA-N	50585779	CHEMBL5088595	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 194							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585779&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166632020	476021866							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450897	CC(C)c1cc(Nc2cc3nc(ccc3cn2)[C@](C)(O)C2CCN(C)CC2)c(F)cn1	InChI=1S/C24H30FN5O/c1-15(2)19-11-21(18(25)14-26-19)29-23-12-20-16(13-27-23)5-6-22(28-20)24(3,31)17-7-9-30(4)10-8-17/h5-6,11-15,17,31H,7-10H2,1-4H3,(H,26,27,29)/t24-/m1/s1	HRKCERYJQXATNH-XMMPIXPASA-N	50585780	CHEMBL5090019	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 147							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585780&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166632368	476021867							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450898	CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(ncc3F)C(F)(F)F)cc2n1	InChI=1S/C22H23F4N5O/c1-21(32,14-5-7-31(2)8-6-14)18-4-3-13-11-28-20(10-16(13)29-18)30-17-9-19(22(24,25)26)27-12-15(17)23/h3-4,9-12,14,32H,5-8H2,1-2H3,(H,27,28,30)/t21-/m1/s1	GHNYLVIESIGHDJ-OAQYLSRUSA-N	50585781	CHEMBL5084200	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 718							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585781	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585781&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			162439673	476021868							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450899	CC(C)c1cc(Nc2cc3nc(ccc3cn2)[C@](C)(O)C2CCN(C)CC2)c(F)cc1C#N	InChI=1S/C26H30FN5O/c1-16(2)20-12-23(21(27)11-18(20)14-28)31-25-13-22-17(15-29-25)5-6-24(30-22)26(3,33)19-7-9-32(4)10-8-19/h5-6,11-13,15-16,19,33H,7-10H2,1-4H3,(H,29,31)/t26-/m1/s1	MOXBYMQBYZTOJA-AREMUKBSSA-N	50585782	CHEMBL5080361	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 104							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585782	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585782&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166629073	476021869							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450900	CC(C)Oc1cc(Nc2cc3nc(ccc3cn2)[C@](C)(O)C2CCN(C)CC2)c(F)cc1C#N	InChI=1S/C26H30FN5O2/c1-16(2)34-23-12-22(20(27)11-18(23)14-28)31-25-13-21-17(15-29-25)5-6-24(30-21)26(3,33)19-7-9-32(4)10-8-19/h5-6,11-13,15-16,19,33H,7-10H2,1-4H3,(H,29,31)/t26-/m1/s1	QRPJDQZOXSLSEK-AREMUKBSSA-N	50585783	CHEMBL5070707	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 161							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585783	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585783&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166625236	476021870							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450901	CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(c(cc3F)C#N)C(F)(F)F)cc2n1	InChI=1S/C24H23F4N5O/c1-23(34,16-5-7-33(2)8-6-16)21-4-3-14-13-30-22(11-19(14)31-21)32-20-10-17(24(26,27)28)15(12-29)9-18(20)25/h3-4,9-11,13,16,34H,5-8H2,1-2H3,(H,30,32)/t23-/m1/s1	WIQLQHJLURUMAP-HSZRJFAPSA-N	50585784	CHEMBL5087911	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 294							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585784	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585784&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166632292	476021871							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450902	CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(N4CC5CCC(C4)O5)c(cc3F)C#N)cc2n1	InChI=1S/C29H33FN6O2/c1-29(37,20-7-9-35(2)10-8-20)27-6-3-18-15-32-28(13-24(18)33-27)34-25-12-26(19(14-31)11-23(25)30)36-16-21-4-5-22(17-36)38-21/h3,6,11-13,15,20-22,37H,4-5,7-10,16-17H2,1-2H3,(H,32,34)/t21?,22?,29-/m1/s1	PHVGAEJTLZFYTO-UQIPPQJZSA-N	50585785	CHEMBL5077028	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 94							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585785	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585785&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166625947	476021872							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51450903	CN1CCC(CC1)[C@@](C)(O)c1ccc2cnc(Nc3cc(ncc3F)C(N)=O)cc2n1	InChI=1S/C22H25FN6O2/c1-22(31,14-5-7-29(2)8-6-14)19-4-3-13-11-26-20(10-16(13)27-19)28-17-9-18(21(24)30)25-12-15(17)23/h3-4,9-12,14,31H,5-8H2,1-2H3,(H2,24,30)(H,25,26,28)/t22-/m1/s1	DDPAPPCCQQJSAP-JOCHJYFZSA-N	50585786	CHEMBL5080813	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 631							ChEMBL	10.1021/acs.jmedchem.1c02069	10.7270/Q2CF9V08	35143203			Daniels, MH; Malojcic, G; Clugston, SL; Williams, B; Coeffet-Le Gal, M; Pan-Zhou, XR; Venkatachalan, S; Harmange, JC; Ledeboer, M	Goldfinc Bio	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50585786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50585786&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166629991	476021873							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51462468	CN(C)C\C=C\C(=O)Nc1ccc(nc1)C(=O)N[C@@]1(C)CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12	InChI=1S/C31H35ClN8O2/c1-31(39-29(42)26-13-12-21(17-33-26)36-27(41)11-7-15-40(2)3)14-6-8-20(16-31)37-30-35-19-24(32)28(38-30)23-18-34-25-10-5-4-9-22(23)25/h4-5,7,9-13,17-20,34H,6,8,14-16H2,1-3H3,(H,36,41)(H,39,42)(H,35,37,38)/b11-7+/t20-,31+/m1/s1	SCJNYBYSTCRPAO-LXBQGUBHSA-N	50528812	CHEMBL4582951	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 20							ChEMBL		10.7270/Q2DF6W53	36561076			Gai, C; Harnor, SJ; Zhang, S; Cano, C; Zhuang, C; Zhao, Q	College of Pharmacy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50528812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50528812&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118426108	440737394							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51462469	CN1CCC[C@H]1COc1nc2CN(CCc2c(n1)N1CCN([C@@H](CC#N)C1)C(=O)C(F)=C)c1cccc2cccc(Cl)c12	InChI=1S/C32H35ClFN7O2/c1-21(34)31(42)41-17-16-40(18-23(41)11-13-35)30-25-12-15-39(28-10-4-7-22-6-3-9-26(33)29(22)28)19-27(25)36-32(37-30)43-20-24-8-5-14-38(24)2/h3-4,6-7,9-10,23-24H,1,5,8,11-12,14-20H2,2H3/t23-,24-/m0/s1	PEMUGDMSUDYLHU-ZEQRLZLVSA-N	50539763	Adagrasib::Mrtx-849::Mrtx849	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 1.3							ChEMBL		10.7270/Q2DF6W53	36561076			Gai, C; Harnor, SJ; Zhang, S; Cano, C; Zhuang, C; Zhao, Q	College of Pharmacy	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50539763	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50539763&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			138611145	442141326							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51459910	CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CCC[C@@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12			50540080	CHEMBL4648857	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8500							ChEMBL		10.7270/Q2HQ43WX	34962782			Lu, X; Smaill, JB; Patterson, AV; Ding, K	Jinan University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50540080	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50540080&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			118033814	442141643							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51458418	CC(C)N1CCc2cc(ccc2C1=O)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F	InChI=1S/C25H28FN7O/c1-16(2)33-10-7-17-13-18(3-5-20(17)24(33)34)23-21(26)15-29-25(31-23)30-22-6-4-19(14-28-22)32-11-8-27-9-12-32/h3-6,13-16,27H,7-12H2,1-2H3,(H,28,29,30,31)	UBHPJEJMHASIRC-UHFFFAOYSA-N	50588661	CHEMBL5205035	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8722							ChEMBL		10.7270/Q2B56PQD	36350721			Chen, W; Ji, M; Cheng, H; Zheng, M; Xia, F; Min, W; Yang, H; Wang, X; Wang, L; Cao, L; Yuan, K; Yang, P	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50588661	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50588661&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			168297332	482599513							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51458419	Fc1cnc(Nc2ccc(cn2)N2CCNCC2)nc1-c1ccc2C(=O)NCCc2c1	InChI=1S/C22H22FN7O/c23-18-13-27-22(28-19-4-2-16(12-26-19)30-9-7-24-8-10-30)29-20(18)15-1-3-17-14(11-15)5-6-25-21(17)31/h1-4,11-13,24H,5-10H2,(H,25,31)(H,26,27,28,29)	RONAHISFEVHOEE-UHFFFAOYSA-N	50588663	CHEMBL5185518	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 8236							ChEMBL		10.7270/Q2B56PQD	36350721			Chen, W; Ji, M; Cheng, H; Zheng, M; Xia, F; Min, W; Yang, H; Wang, X; Wang, L; Cao, L; Yuan, K; Yang, P	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50588663	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50588663&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			168284243	482599515							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51458420	CCN1CCc2cc(ccc2C1=O)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F	InChI=1S/C24H26FN7O/c1-2-31-10-7-16-13-17(3-5-19(16)23(31)33)22-20(25)15-28-24(30-22)29-21-6-4-18(14-27-21)32-11-8-26-9-12-32/h3-6,13-15,26H,2,7-12H2,1H3,(H,27,28,29,30)	CXRFVRQTMSLWOK-UHFFFAOYSA-N	50588664	CHEMBL5170480	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 2595							ChEMBL		10.7270/Q2B56PQD	36350721			Chen, W; Ji, M; Cheng, H; Zheng, M; Xia, F; Min, W; Yang, H; Wang, X; Wang, L; Cao, L; Yuan, K; Yang, P	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50588664	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50588664&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			166176929	482599516							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51458421	CN1CCc2cc(ccc2C1=O)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F	InChI=1S/C23H24FN7O/c1-30-9-6-15-12-16(2-4-18(15)22(30)32)21-19(24)14-27-23(29-21)28-20-5-3-17(13-26-20)31-10-7-25-8-11-31/h2-5,12-14,25H,6-11H2,1H3,(H,26,27,28,29)	RBMBLJOYIGVBNO-UHFFFAOYSA-N	50588665	CHEMBL5171767	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL		10.7270/Q2B56PQD	36350721			Chen, W; Ji, M; Cheng, H; Zheng, M; Xia, F; Min, W; Yang, H; Wang, X; Wang, L; Cao, L; Yuan, K; Yang, P	China Pharmaceutical University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50588665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50588665&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			168270451	482599517							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322412	CN(C)C(=O)n1cc(-c2nc(N[C@H]3CCC(C)(C)NC3)ncc2C(F)(F)F)c2ccc(O)cc12	InChI=1S/C23H27F3N6O2/c1-22(2)8-7-13(10-28-22)29-20-27-11-17(23(24,25)26)19(30-20)16-12-32(21(34)31(3)4)18-9-14(33)5-6-15(16)18/h5-6,9,11-13,28,33H,7-8,10H2,1-4H3,(H,27,29,30)/t13-/m0/s1	KEFMDBNSOZOKGL-ZDUSSCGKSA-N	619409	US20230295130, Example T-33	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619409&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163704897	485226715							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322413	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)(F)F)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619410	US20230295130, Example T-34	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619410&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428875	485226716							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322417	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619411	US20230295130, Example T-35	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619411&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428876	485226717							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322421	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619412	US20230295130, Example T-36	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619412&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428877	485226718							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322425	COC(=O)Nc1ccc2c(c[nH]c2c1OC)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619413	US20230295130, Example T-37	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619413&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428878	485226719							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322429	COC(=O)Nc1ccc2c(c[nH]c2c1OC)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619414	US20230295130, Example T-38	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619414&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428879	485226720							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322430	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCNC2)ncc1C(F)(F)F			619415	US20230295130, Example T-39	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619415&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428880	485226721							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322431	COC(=O)Nc1ccc2c(cn(C)c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F	InChI=1S/C21H22BrF3N6O2/c1-31-10-13(12-5-6-15(16(22)18(12)31)29-20(32)33-2)17-14(21(23,24)25)9-27-19(30-17)28-11-4-3-7-26-8-11/h5-6,9-11,26H,3-4,7-8H2,1-2H3,(H,29,32)(H,27,28,30)/t11-/m0/s1	MURADGLCIZTJLN-NSHDSACASA-N	619416	US20230295130, Example T-40	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619416&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428881	485226722							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322432	COC(=O)N(C)c1ccc2c(cn(C)c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F	InChI=1S/C22H24BrF3N6O2/c1-31-11-14(13-6-7-16(17(23)19(13)31)32(2)21(33)34-3)18-15(22(24,25)26)10-28-20(30-18)29-12-5-4-8-27-9-12/h6-7,10-12,27H,4-5,8-9H2,1-3H3,(H,28,29,30)/t12-/m0/s1	KDMWJFUIMNXUPH-LBPRGKRZSA-N	619417	US20230295130, Example T-41	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619417&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428882	485226723							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322433	CCOC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619418	US20230295130, Example T-42	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619418&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428883	485226724							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322437	CCOC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@@H]2CNCC(C)(C)C2)ncc1C(F)(F)F			619419	US20230295130, Example T-43	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619419&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428884	485226725							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322441	CC(C)OC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619420	US20230295130, Example T-44	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619420&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428885	485226726							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322445	CCCOC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619421	US20230295130, Example T-45	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619421&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428886	485226727							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322446	FC(F)(F)c1cnc(N[C@H]2CCNC2)nc1-c1c[nH]c2c(Br)c(ccc12)N1CCOC1=O			619422	US20230295130, Example T-46	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619422&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428887	485226728							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322447	FC(F)(F)c1cnc(N[C@H]2CCNC2)nc1-c1c[nH]c2c(Br)c(ccc12)N1CCCC1=O			619423	US20230295130, Example T-47	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619423&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428888	485226729							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322448	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(O[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619424	US20230295130, Example T-48	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619424&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428889	485226730							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322452	FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2cc(ccc12)N1CCOC1=O			619425	US20230295130, Example T-49	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619425&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428890	485226731							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322453	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC[C@H](O)C2)ncc1C(F)(F)F			619406	US20230295130, Example T-30::US20230295130, Example T-50	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619406&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428872	485226712							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322454	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC[C@@H](O)C2)ncc1C(F)(F)F			619405	US20230295130, Example T-29::US20230295130, Example T-51	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619405&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428871	485226711							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322455	COC(=O)Nc1ccc2c(c[nH]c2c1C)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619428	US20230295130, Example T-52	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619428&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428891	485226732							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322459	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CC[C@@H](N)C2)ncc1C(F)(F)F			619429	US20230295130, Example T-53	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619429	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619429&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428892	485226733							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322460	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CC[C@H](N)C2)ncc1C(F)(F)F			619430	US20230295130, Example T-54	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619430&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428893	485226734							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322461	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@@H]2CC[C@H](N)C2)ncc1C(F)(F)F			619431	US20230295130, Example T-55	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619431&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428894	485226735							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322462	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@@H]2CC[C@@H](N)C2)ncc1C(F)(F)F			619432	US20230295130, Example T-56	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619432&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428895	485226736							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322463	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@@H]2CCC[C@H]2N)ncc1C(F)(F)F			619433	US20230295130, Example T-57	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619433&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428896	485226737							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322464	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@@H]2CCC[C@@H]2N)ncc1C(F)(F)F			619434	US20230295130, Example T-58	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619434&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428897	485226738							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322465	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC[C@H]2N)ncc1C(F)(F)F			619435	US20230295130, Example T-59	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619435&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428898	485226739							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322466	COC(=O)Nc1ccc2c(c[nH]c2c1-c1ccccc1)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619436	US20230295130, Example T-60	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619436&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428899	485226740							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322470	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@@H]2CCNC2)ncc1C(F)(F)F			619437	US20230295130, Example T-61	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619437&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428900	485226741							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322471	COCCOC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619438	US20230295130, Example T-62	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619438&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428901	485226742							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322475	COC(=O)Nc1ccc2c(c[nH]c2c1S(=O)(=O)C(C)C)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619439	US20230295130, Example T-63	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619439&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428902	485226743							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322479	COC(=O)Nc1ccc2c(c[nH]c2c1S(=O)(=O)C(C)C)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619440	US20230295130, Example T-64	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619440&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428903	485226744							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322483	COC(=O)Nc1ccc2c(c[nH]c2c1S(=O)C(C)C)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619441	US20230295130, Example T-65	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619441	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619441&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428904	485226745							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322487	COC(=O)Nc1ccc2c(c[nH]c2c1SC(C)C)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619442	US20230295130, Example T-66	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619442	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619442&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428905	485226746							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322491	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC[C@@H]2N)ncc1C(F)(F)F			619443	US20230295130, Example T-67	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619443	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619443&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428906	485226747							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322495	COC(=O)Nc1ccc2c(c[nH]c2c1-c1cnn(C)c1)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619444	US20230295130, Example T-68	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619444&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428907	485226748							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322499	COC(=O)Nc1ccc2c(c[nH]c2c1C(C)C)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619445	US20230295130, Example T-69	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619445&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428908	485226749							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322503	COC(=O)Nc1ccc2c(c[nH]c2c1C(C)=C)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619446	US20230295130, Example T-70	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619446&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428909	485226750							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322507	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1Cl			619447	US20230295130, Example T-71	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619447&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428910	485226751							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322508	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1Cl			619448	US20230295130, Example T-72	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619448	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619448&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428911	485226752							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322509	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(Oc2ccc(C)nc2)ncc1C(F)(F)F	InChI=1S/C21H15BrF3N5O3/c1-10-3-4-11(7-26-10)33-19-28-9-14(21(23,24)25)17(30-19)13-8-27-18-12(13)5-6-15(16(18)22)29-20(31)32-2/h3-9,27H,1-2H3,(H,29,31)	GFDPUQQPKJMXMH-UHFFFAOYSA-N	619449	US20230295130, Example T-73	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619449	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619449&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428912	485226753							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322510	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(O[C@@H]2CCCNC2)ncc1C(F)(F)F			619450	US20230295130, Example T-74	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619450	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619450&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428913	485226754							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322511	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1Br			619451	US20230295130, Example T-75	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619451	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619451&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428914	485226755							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322515	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C			619452	US20230295130, Example T-76	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619452&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428915	485226756							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322516	CCc1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2c(Br)c(NC(=O)OC)ccc12			619453	US20230295130, Example T-77	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619453	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619453&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428916	485226757							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322517	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(C)C			619454	US20230295130, Example T-78	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619454	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619454&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428917	485226758							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322518	COC(=O)Nc1ccc2c(c[nH]c2c1Cl)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619455	US20230295130, Example T-79	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619455	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619455&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428918	485226759							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322522	COC(=O)Nc1ccc2c(c[nH]c2c1Cl)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619456	US20230295130, Example T-80	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619456	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619456&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428919	485226760							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322526	COC(=O)Nc1ccc2c(c[nH]c2c1Cl)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619457	US20230295130, Example T-81	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619457	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619457&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428920	485226761							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322530	CCOC(=O)Nc1ccc2c(c[nH]c2c1Cl)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619458	US20230295130, Example T-82	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619458	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619458&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428921	485226762							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322534	COC(=O)Nc1ccc2c(c[nH]c2c1C1CCOC1)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619459	US20230295130, Example T-83	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619459	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619459&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428922	485226763							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322535	COC(=O)Nc1ccc2c(c[nH]c2c1C1COC1)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619460	US20230295130, Example T-84	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619460&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428923	485226764							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322539	COC(=O)Nc1ccc2c(c[nH]c2c1OCC(F)(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1Cl			619461	US20230295130, Example T-85	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619461	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619461&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428924	485226765							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322543	COC(=O)Nc1ccc2c(c[nH]c2c1CC(F)(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1Cl			619462	US20230295130, Example T-86	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619462	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619462&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428925	485226766							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322547	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1Cl			619463	US20230295130, Example T-87	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619463	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619463&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428926	485226767							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322548	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)(F)F)-c1nc(N[C@H]2CCCNC2)ncc1Cl			619464	US20230295130, Example T-88	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619464	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619464&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428927	485226768							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322552	COC(=O)Nc1ccc2c(c[nH]c2c1SC(C)C)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619465	US20230295130, Example T-89	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619465	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619465&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428928	485226769							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322553	COC(=O)Nc1ccc2c(c[nH]c2c1C#C)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619466	US20230295130, Example T-90	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619466	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619466&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428929	485226770							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322554	COC(=O)Nc1ccc2c(c[nH]c2c1OCC(F)(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619467	US20230295130, Example T-91	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619467&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428930	485226771							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322555	COC(=O)Nc1ccc2c(c[nH]c2c1OC1CCCC1)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619468	US20230295130, Example T-92	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619468&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428931	485226772							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322556	COC(=O)Nc1ccc2c(c[nH]c2c1OC1CCC1)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619469	US20230295130, Example T-93	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619469	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619469&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428932	485226773							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322557	COC(=O)Nc1ccc2c(c[nH]c2c1OC(C)C)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619470	US20230295130, Example T-94	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619470	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619470&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428933	485226774							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322558	CCOc1c(NC(=O)OC)ccc2c(c[nH]c12)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619471	US20230295130, Example T-95	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619471	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619471&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428934	485226775							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322559	COC(=O)Nc1ccc2c(c[nH]c2c1OC(F)(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1Cl			619472	US20230295130, Example T-96	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619472&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428935	485226776							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322563	COC(=O)Nc1ccc2c(c[nH]c2c1CC(F)(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619473	US20230295130, Example T-97	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619473&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428936	485226777							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322564	COC(=O)Nc1ccc2c(c[nH]c2c1C(C)(F)F)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619474	US20230295130, Example T-99	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619474&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428937	485226778							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322565	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)(F)F)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619475	US20230295130, Example T-100	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619475&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058673	485226779							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322569	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)(F)F)-c1nc(N[C@@H]2CNCC(C)(C)C2)ncc1C(F)(F)F			619476	US20230295130, Example T-101	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619476&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058690	485226780							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322570	COC(=O)N(C)c1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619477	US20230295130, Example T-102	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619477&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058705	485226781							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322574	COC(=O)N(C)c1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619477	US20230295130, Example T-102	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619477&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058705	485226781							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322578	COC(=O)N(C)c1ccc2c(c[nH]c2c1P(C)(C)=O)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619478	US20230295130, Example T-103	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619478&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428938	485226782							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322579	COC(=O)Nc1ccc2c(c[nH]c2c1C1CC1(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619479	US20230295130, Example T-105	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619479&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428939	485226783							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322583	COC(=O)Nc1ccc2c(c[nH]c2c1C1CC(F)(F)C1)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619480	US20230295130, Example T-106	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619480&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428940	485226784							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322587	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619481	US20230295130, Example T-107	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619481&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428941	485226785							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322591	COC(=O)Nc1ccc2c(c[nH]c2c1OC(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619482	US20230295130, Example T-108	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619482	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619482&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428942	485226786							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322595	COC(=O)Nc1ccc2c(c[nH]c2c1OC(F)(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619483	US20230295130, Example T-109	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619483&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428943	485226787							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322599	COC(=O)Nc1ccc2c(c[nH]c2c1OC(F)F)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619484	US20230295130, Example T-110::US20230295130, Example T-154	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619484&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058661	485226788							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322600	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)(F)F)-c1nc(N[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619485	US20230295130, Example T-111::US20230295130, Example T-172	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619485&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058714	485226789							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322601	CCN[C@H]1CCC[C@@H]1Nc1ncc(c(n1)-c1c[nH]c2c(Br)c(NC(=O)OC)ccc12)C(F)(F)F			619486	US20230295130, Example T-115	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619486&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428944	485226790							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322602	CCN[C@H]1CCC[C@@H]1Nc1ncc(c(n1)-c1c[nH]c2c(c(NC(=O)OC)ccc12)C(F)(F)F)C(F)(F)F			619487	US20230295130, Example T-117	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619487&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428945	485226791							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322603	COC(=O)Nc1ccc2c(c[nH]c2c1OC(F)F)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619488	US20230295130, Example T-121	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619488&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428946	485226792							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322604	COC(=O)Nc1ccc2c(c[nH]c2c1OC(F)(F)F)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619489	US20230295130, Example T-122	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619489&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428947	485226793							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322605	COC(=O)Nc1ccc2c(c[nH]c2c1OC(F)(F)F)-c1nc(N[C@H]2CCCNC2)ncc1Cl			619490	US20230295130, Example T-123	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619490&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428948	485226794							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322606	COC(=O)Nc1ccc2c(c[nH]c2c1Cl)-c1nc(NC2CNC3CC3C2)ncc1C(F)(F)F			619491	US20230295130, Example T-126	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619491&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428949	485226795							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322607	CCOC(=O)Nc1ccc2c(c[nH]c2c1C1CC1)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619492	US20230295130, Example T-127	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619492&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428950	485226796							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322611	COC(=O)Nc1ccc2c(c[nH]c2c1C1CC1)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619493	US20230295130, Example T-128	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619493&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428951	485226797							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322615	COC(=O)Nc1ccc2c(c[nH]c2c1C1CC1)-c1nc(N[C@H]2CCC(C)NC2)ncc1C(F)(F)F			619494	US20230295130, Example T-129	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619494&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428952	485226798							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322619	COC(=O)Nc1ccc2c(c[nH]c2c1C1CC1)-c1nc(N[C@H]2CC[C@@H](C)NC2)ncc1C(F)(F)F			619495	US20230295130, Example T-130	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619495&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428953	485226799							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322623	COC(=O)Nc1ccc2c(c[nH]c2c1C1CC1)-c1nc(N[C@H]2CC[C@H](C)NC2)ncc1C(F)(F)F			619496	US20230295130, Example T-131	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619496&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428954	485226800							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322627	COC(=O)Nc1ccc2c(c[nH]c2c1OC)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619497	US20230295130, Example T-132	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619497&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428955	485226801							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322631	COC(=O)Nc1ccc2c(c[nH]c2c1OC)-c1nc(N[C@@H]2CNC(C)=CC2)ncc1C(F)(F)F			619498	US20230295130, Example T-133	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619498&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428956	485226802							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322632	COC(=O)Nc1ccc2c(c[nH]c2c1C(C)=O)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619499	US20230295130, Example T-134	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619499&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058666	485226803							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322636	COC(=O)Nc1ccc2c(c[nH]c2c1C(C)=O)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619500	US20230295130, Example T-135	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619500&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058721	485226804							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322640	COC(=O)Nc1ccc2c(c[nH]c2c1C(C)(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619501	US20230295130, Example T-136	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619501&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058684	485226805							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322644	COC(=O)Nc1ccc2c(c[nH]c2c1C(C)(F)F)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619502	US20230295130, Example T-137	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619502&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058688	485226806							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322648	CCOc1c(NC(=O)OC)ccc2c(c[nH]c12)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619503	US20230295130, Example T-138	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619503&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428957	485226807							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322652	COC(=O)Nc1ccc2c(c[nH]c2c1OCC(F)(F)F)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619504	US20230295130, Example T-139	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619504&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428958	485226808							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322656	COC(=O)Nc1ccc2c(c[nH]c2c1OC)-c1nc(N[C@H]2CC[C@@H](C)NC2)ncc1C(F)(F)F			619505	US20230295130, Example T-140	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619505&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428959	485226809							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322660	COC(=O)Nc1ccc2c(c[nH]c2c1OC)-c1nc(N[C@H]2CC[C@H](C)NC2)ncc1C(F)(F)F			619506	US20230295130, Example T-141	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619506&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428960	485226810							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322661	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619507	US20230295130, Example T-142	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619507&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428961	485226811							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322665	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CC[C@@H](C)NC2)ncc1C(F)(F)F			619508	US20230295130, Example T-143	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619508&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428962	485226812							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322669	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CC[C@H](C)NC2)ncc1C(F)(F)F			619509	US20230295130, Example T-144	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619509	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619509&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428963	485226813							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322670	COC(=O)Nc1ccc2c(c[nH]c2c1Cl)-c1nc(N[C@H]2CCC(C)NC2)ncc1C(F)(F)F			619510	US20230295130, Example T-145	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619510	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619510&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058648	485226814							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322671	COC(=O)Nc1ccc2c(c[nH]c2c1Cl)-c1nc(N[C@H]2CC[C@@H](C)NC2)ncc1C(F)(F)F			619511	US20230295130, Example T-146	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619511	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619511&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058706	485226815							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322675	COC(=O)Nc1ccc2c(c[nH]c2c1Cl)-c1nc(N[C@H]2CC[C@H](C)NC2)ncc1C(F)(F)F			619512	US20230295130, Example T-147	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619512&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058689	485226816							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322676	COC(=O)Nc1ccc2c(c[nH]c2c1Cl)-c1nc(N[C@@H]2CNC(C)=CC2)ncc1C(F)(F)F			619513	US20230295130, Example T-148	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619513&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058691	485226817							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322677	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)(F)F)-c1nc(N[C@H]2CC[C@@H](C)NC2)ncc1C(F)(F)F			619514	US20230295130, Example T-149	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619514	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619514&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058715	485226818							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322681	COC(=O)Nc1ccc2c(c[nH]c2c1OCC(F)(F)F)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619515	US20230295130, Example T-150	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619515&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428964	485226819							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322685	COC(=O)Nc1ccc2c(c[nH]c2c1OCC(F)(F)F)-c1nc(N[C@H]2CC[C@@H](C)NC2)ncc1C(F)(F)F			619516	US20230295130, Example T-151	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619516&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428965	485226820							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322689	COC(=O)Nc1ccc2c(c[nH]c2c1OCC(F)(F)F)-c1nc(N[C@H]2CC[C@H](C)NC2)ncc1C(F)(F)F			619517	US20230295130, Example T-152	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619517&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428966	485226821							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322690	CCOC(=O)Nc1ccc2c(c[nH]c2c1C(C)(F)F)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619518	US20230295130, Example T-153	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619518&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058654	485226822							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322694	COC(=O)Nc1ccc2c(c[nH]c2c1OC(F)F)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619484	US20230295130, Example T-110::US20230295130, Example T-154	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619484&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058661	485226788							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322698	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)F)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619520	US20230295130, Example T-155	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619520	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619520&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058699	485226823							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322702	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)F)-c1nc(N[C@H]2CCC3(CC3)NC2)ncc1C(F)(F)F			619521	US20230295130, Example T-156	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619521	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619521&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428967	485226824							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322706	COC(=O)Nc1ccc2c(c[nH]c2c1C(C)(C)O)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619522	US20230295130, Example T-157	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619522	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619522&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058669	485226825							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322707	CC(=O)Nc1ccc2c(c[nH]c2c1C(C)(C)O)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619523	US20230295130, Example T-158	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619523	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619523&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428968	485226826							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322708	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)F)-c1nc(N[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619524	US20230295130, Example T-160::US20230295130, Example T-169	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619524	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619524&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058701	485226827							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322712	CCOc1c(NC(=O)OC)ccc2c(c[nH]c12)-c1nc(N[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619525	US20230295130, Example T-161	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619525	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619525&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058713	485226828							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322716	COC(=O)N(C)c1ccc2c(c[nH]c2c1Cl)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619526	US20230295130, Example T-162	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619526	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619526&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058656	485226829							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322720	COC(=O)N(C)c1ccc2c(c[nH]c2c1C(F)F)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619527	US20230295130, Example T-163	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619527	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619527&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058651	485226830							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322724	COC(=O)N(C)c1ccc2c(c[nH]c2c1C(F)(F)F)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619528	US20230295130, Example T-164	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619528	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619528&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058696	485226831							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322728	COC(=O)N(C)c1ccc2c(c[nH]c2c1OC(F)F)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619529	US20230295130, Example T-165	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619529	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619529&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058694	485226832							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322732	COC(=O)N(C)c1ccc2c(c[nH]c2c1OC)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619530	US20230295130, Example T-166	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619530	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619530&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058682	485226833							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322733	COC(=O)Nc1ccc2c(c[nH]c2c1OC)-c1nc(N[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619531	US20230295130, Example T-167	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619531&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163925087	485226834							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322734	COC(=O)Nc1ccc2c(c[nH]c2c1Cl)-c1nc(N[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619532	US20230295130, Example T-168	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619532	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619532&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058657	485226835							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322738	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)F)-c1nc(N[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619524	US20230295130, Example T-160::US20230295130, Example T-169	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619524	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619524&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058701	485226827							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322742	COC(=O)N(C)c1ccc2c(c[nH]c2c1C(C)(F)F)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619534	US20230295130, Example T-170	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619534&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058697	485226836							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322743	COC(=O)Nc1ccc2c(c[nH]c2c1C(C)(F)F)-c1nc(N[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619535	US20230295130, Example T-171	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619535&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428969	485226837							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322744	COC(=O)Nc1ccc2c(c[nH]c2c1C(F)(F)F)-c1nc(N[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619485	US20230295130, Example T-111::US20230295130, Example T-172	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619485&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058714	485226789							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322745	COC(=O)Nc1ccc2c(c[nH]c2c1OC(F)F)-c1nc(N[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619537	US20230295130, Example T-173	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619537&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058649	485226838							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322746	COC(=O)Nc1ccc2c(c[nH]c2c1C1CC1)-c1nc(N[C@H]2CCCN(C)C2)ncc1C(F)(F)F			619538	US20230295130, Example T-174	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619538&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058678	485226839							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322747	COC(=O)N(C)c1ccc2c(c[nH]c2c1C1CC1)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619539	US20230295130, Example T-175	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619539&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058662	485226840							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322748	CN[C@@H]1CC2OC([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C27H24N4O3/c1-28-16-11-19-30-17-9-5-4-8-14(17)21-22-15(12-29-26(22)32)20-13-7-3-6-10-18(13)31(23(20)24(21)30)27(34-19)25(16)33-2/h3-10,16,19,25,27-28H,11-12H2,1-2H3,(H,29,32)/t16-,19?,25-,27?/m1/s1	YISMQBFJYDFMAL-AESIHLKFSA-N	139540	US10189849, staurosporine::US10307427, Staurosporine::US10329300, Staurosporine::US11091485, Compound Staurosporine::US11542261, Compound staurosporine::US20230312583, Compound staurosporine::US8889696, Staurosporine::US9051313, Staurosporine::US9586965, Control Staurosporine	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139540&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91669270	249871008							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322749	CC1(C)CC[C@@H](CN1)Nc1ncc(c(n1)-c1c[nH]c2c(c(ccc12)C#N)P1(=O)CCCC1)C(F)(F)F			619541	US20230295130, Compound 01	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619541&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			168170998	485226842							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322750	CC1(C)CC[C@@H](CN1)Nc1ncc(c(n1)-c1c[nH]c2c(c(ccc12)N1CCCCC1=O)P(C)(C)=O)C(F)(F)F			619542	US20230295130, Compound 02	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619542&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058671	485226843							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322751	Cc1cc(Nc2ncc(c(n2)-c2c[nH]c3cc(ccc23)C#N)C(F)(F)F)n[nH]1	InChI=1S/C18H12F3N7/c1-9-4-15(28-27-9)25-17-24-8-13(18(19,20)21)16(26-17)12-7-23-14-5-10(6-22)2-3-11(12)14/h2-5,7-8,23H,1H3,(H2,24,25,26,27,28)	GNKGLQZWCXRWIG-UHFFFAOYSA-N	619543	US20230295130, Compound 12	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619543&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058712	485226844							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322752	CC1(C)CC[C@@H](CN1)Nc1ncc(c(n1)-c1c[nH]c2c(nccc12)P1(=O)CCCC1)C(F)(F)F			619544	US20230295130, Compound 14	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619544&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058687	485226845							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322753	COC(=O)Nc1ccc2c(c[nH]c2c1P1(=O)CCCC1)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619545	US20230295130, Compound 20	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619545&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169058704	485226846							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322754	CC1(C)CC[C@@H](CN1)Nc1ncc(c(n1)-c1c[nH]c2c(c(ccc12)C#N)S(=O)(=O)C1CCCC1)C(F)(F)F			619546	US20230295130, Compound 23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619546	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619546&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428970	485226847							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322755	CC1(C)CC[C@@H](CN1)Nc1nc(-c2c[nH]c3c(c(ccc23)C#N)P(C)(C)=O)c2ccccc2n1			619547	US20230295130, Compound 24	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619547&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428971	485226848							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322756	Cc1cc(Nc2ncc(c(n2)-c2c[nH]c3c(c(ccc23)C#N)P(C)(C)=O)C(F)(F)F)n[nH]1	InChI=1S/C20H17F3N7OP/c1-10-6-15(30-29-10)27-19-26-9-14(20(21,22)23)16(28-19)13-8-25-17-12(13)5-4-11(7-24)18(17)32(2,3)31/h4-6,8-9,25H,1-3H3,(H2,26,27,28,29,30)	NYNZXMOJODJLBB-UHFFFAOYSA-N	619548	US20230295130, Compound 28	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619548&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428972	485226849							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322757	CC1(C)CC[C@@H](CN1)Nc1ncc(c(n1)[N]1=CNc2c1ccc(C#N)c2P(C)(C)=O)C(F)(F)F	InChI=1S/C22H26F3N7OP/c1-21(2)8-7-14(10-29-21)30-20-27-11-15(22(23,24)25)19(31-20)32-12-28-17-16(32)6-5-13(9-26)18(17)34(3,4)33/h5-6,11-12,14,28-29H,7-8,10H2,1-4H3,(H,27,30,31)/t14-/m0/s1	WUROSYUQHLDTJY-AWEZNQCLSA-N	619549	US20230295130, Compound 31	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619549&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428973	485226850							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322758	CP(C)(=O)c1c(ccc2c(c[nH]c12)-c1nc(N[C@H]2CCC(=O)NC2)ncc1C(F)(F)F)C#N			619550	US20230295130, Compound 48	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619550&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428974	485226851							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322759	COC(=O)N[C@H]1CCC[C@H](C1)Nc1ncc(c(n1)-c1c[nH]c2c(c(ccc12)C#N)P(C)(C)=O)C(F)(F)F			619551	US20230295130, Compound 66	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619551&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428975	485226852							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322286	CN[C@@H]1CC2OC([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C27H24N4O3/c1-28-16-11-19-30-17-9-5-4-8-14(17)21-22-15(12-29-26(22)32)20-13-7-3-6-10-18(13)31(23(20)24(21)30)27(34-19)25(16)33-2/h3-10,16,19,25,27-28H,11-12H2,1-2H3,(H,29,32)/t16-,19?,25-,27?/m1/s1	YISMQBFJYDFMAL-AESIHLKFSA-N	139540	US10189849, staurosporine::US10307427, Staurosporine::US10329300, Staurosporine::US11091485, Compound Staurosporine::US11542261, Compound staurosporine::US20230312583, Compound staurosporine::US8889696, Staurosporine::US9051313, Staurosporine::US9586965, Control Staurosporine	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=139540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=139540&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			91669270	249871008							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322290	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619377	US20230295130, Example T-01	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619377&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			162641734	485226683							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322294	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(O[C@H]2CCCNC2)ncc1C(F)(F)F			619378	US20230295130, Example T-02	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619378&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428847	485226684							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322298	FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2c(Br)c(ccc12)N1CCCCC1=O			619379	US20230295130, Example T-03	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619379&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428848	485226685							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322302	FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2c(Br)c(ccc12)N1CCCC1=O			619380	US20230295130, Example T-04	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619380&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428849	485226686							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322306	CN1CCC[C@@H](C1)Nc1ncc(c(n1)-c1c[nH]c2cc(ccc12)N1CCCC1=O)C(F)(F)F			619381	US20230295130, Example T-05	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619381&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428850	485226687							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322310	FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2c(Br)c(ccc12)N1CCCOC1=O			619382	US20230295130, Example T-06	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619382&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428851	485226688							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322314	CC1(C)COC(Nc2ccc3c(c[nH]c3c2Br)-c2nc(N[C@H]3CCCNC3)ncc2C(F)(F)F)=N1			619383	US20230295130, Example T-07	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619383&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428852	485226689							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322318	FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2c(Br)c(NC(=O)C3CC3)ccc12			619384	US20230295130, Example T-08	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619384&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428853	485226690							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322322	CC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619385	US20230295130, Example T-09	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619385&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428854	485226691							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322326	CC(=O)Nc1ccc2c(c[nH]c2c1)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619386	US20230295130, Example T-10	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619386&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428855	485226692							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322330	FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2cc(NC(=O)C3CC3)ccc12			619387	US20230295130, Example T-11	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619387&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428856	485226693							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322334	FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2c(Br)c(ccc12)N1CCOC1=O			619388	US20230295130, Example T-12	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619388&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428857	485226694							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322338	FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2cc(ccc12)N1CCCC1=O			619389	US20230295130, Example T-13	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619389&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428858	485226695							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322342	COC(=O)Nc1ccc2c(c[nH]c2c1P(C)(C)=O)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619390	US20230295130, Example T-14	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619390&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163907360	485226696							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322346	CC(=O)Nc1ccc2c(c[nH]c2c1P(C)(C)=O)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619391	US20230295130, Example T-15	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619391&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			163980609	485226697							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322350	COC(=O)Nc1ccc2c(c[nH]c2c1)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619392	US20230295130, Example T-16	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619392&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428859	485226698							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322354	COC(=O)Nc1ccc2c(c[nH]c2c1C1CC1)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619393	US20230295130, Example T-17	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619393&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428860	485226699							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322358	FC(F)(F)c1cnc(N[C@H]2CCCNC2)nc1-c1c[nH]c2c(Br)c(ccc12)N1CCC1=O			619394	US20230295130, Example T-18	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619394&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428861	485226700							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322362	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(NC2CC3(CNC3)C2)ncc1C(F)(F)F	InChI=1S/C21H20BrF3N6O2/c1-33-19(32)30-14-3-2-11-12(6-27-17(11)15(14)22)16-13(21(23,24)25)7-28-18(31-16)29-10-4-20(5-10)8-26-9-20/h2-3,6-7,10,26-27H,4-5,8-9H2,1H3,(H,30,32)(H,28,29,31)	TVAJQMOTNSNWDG-UHFFFAOYSA-N	619395	US20230295130, Example T-19	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619395&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428862	485226701							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322366	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC[C@H](N)C2)ncc1C(F)(F)F			619396	US20230295130, Example T-20	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619396&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428863	485226702							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322370	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC[C@@H](N)C2)ncc1C(F)(F)F			619397	US20230295130, Example T-21	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619397&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428864	485226703							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322374	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@@H]2CCC[C@H](N)C2)ncc1C(F)(F)F			619398	US20230295130, Example T-22	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619398&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428865	485226704							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322378	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@@H]2CCC[C@@H](N)C2)ncc1C(F)(F)F			619399	US20230295130, Example T-23	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619399&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428866	485226705							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322382	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@@H]2[C@H]3CNC[C@@H]23)ncc1C(F)(F)F			619400	US20230295130, Example T-24	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619400&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428867	485226706							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322386	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2[C@H]3CNC[C@@H]23)ncc1C(F)(F)F			619401	US20230295130, Example T-25	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619401&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428867	485226707							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322390	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(NC2C3CCNC23)ncc1C(F)(F)F			619402	US20230295130, Example T-26	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619402&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428868	485226708							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322394	COC(=O)Nc1ccc2c(c[nH]c2c1C#N)-c1nc(N[C@H]2CCCNC2)ncc1C(F)(F)F			619403	US20230295130, Example T-27	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619403&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428869	485226709							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322398	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(NC2CC3CNCC3C2)ncc1C(F)(F)F			619404	US20230295130, Example T-28	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619404&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428870	485226710							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322402	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC[C@@H](O)C2)ncc1C(F)(F)F			619405	US20230295130, Example T-29::US20230295130, Example T-51	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619405&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428871	485226711							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322406	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(N[C@H]2CCC[C@H](O)C2)ncc1C(F)(F)F			619406	US20230295130, Example T-30::US20230295130, Example T-50	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>500							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619406&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428872	485226712							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322407	COC(=O)Nc1ccc2c(c[nH]c2c1Br)-c1nc(NC2CC3(CC(N)C3)C2)ncc1C(F)(F)F	InChI=1S/C22H22BrF3N6O2/c1-34-20(33)31-15-3-2-12-13(8-28-18(12)16(15)23)17-14(22(24,25)26)9-29-19(32-17)30-11-6-21(7-11)4-10(27)5-21/h2-3,8-11,28H,4-7,27H2,1H3,(H,31,33)(H,29,30,32)	JICAIOWSCOLKSA-UHFFFAOYSA-N	619407	US20230295130, Example T-31	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<50							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619407&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428873	485226713							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1322411	CN(C)C(=O)Oc1ccc2c(c[nH]c2c1)-c1nc(N[C@H]2CCC(C)(C)NC2)ncc1C(F)(F)F			619408	US20230295130, Example T-32	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 275							US Patent		10.7270/Q2TB1C2B			US20230295130	LI, J; LIANG, A; WU, Y; DONG, S; LI, M; NIU, C	TYK MEDICINES, INC.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=619408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=619408&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169428874	485226714							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P6V,8P6Y	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8ORM,8P4Z,8P6V,8P6Y	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ,8ORM,8P6V,8P6Y	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51506576	CN1CCN(CC1)c1ccc(Nc2ncc3nc(C(C)=O)c(=O)n(C4CCCC4)c3n2)cc1	InChI=1S/C24H29N7O2/c1-16(32)21-23(33)31(19-5-3-4-6-19)22-20(27-21)15-25-24(28-22)26-17-7-9-18(10-8-17)30-13-11-29(2)12-14-30/h7-10,15,19H,3-6,11-14H2,1-2H3,(H,25,26,28)	CPKLUQZOENPOAC-UHFFFAOYSA-N	50606945	CHEMBL5218782	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL		10.7270/Q28S4V1B	36130661			He, H; Liu, Q; Chen, L; Wang, J; Yuan, Y; Li, H; Qian, X; Zhao, Z; Chen, Z	East China University of Science & Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50606945	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50606945&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			168299155	482617796							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51506577	CCN1CCN(CC1)c1ccc(Nc2ncc3nc(C(C)=O)c(=O)n(C4CCCC4)c3n2)cc1	InChI=1S/C25H31N7O2/c1-3-30-12-14-31(15-13-30)19-10-8-18(9-11-19)27-25-26-16-21-23(29-25)32(20-6-4-5-7-20)24(34)22(28-21)17(2)33/h8-11,16,20H,3-7,12-15H2,1-2H3,(H,26,27,29)	JWXFZMDNUUBYBZ-UHFFFAOYSA-N	50606946	CHEMBL5220823	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>10000							ChEMBL		10.7270/Q28S4V1B	36130661			He, H; Liu, Q; Chen, L; Wang, J; Yuan, Y; Li, H; Qian, X; Zhao, Z; Chen, Z	East China University of Science & Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50606946	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50606946&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167312199	482617797							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
51506578	CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	HKSZLNNOFSGOKW-FYTWVXJKSA-N	2579	(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::CHEMBL388978::Staurosporin, 4::Staurosporine::Staurosporine, 8::US9206188, Staurosporine::US9226923, Staurosporine	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 107							ChEMBL		10.7270/Q28S4V1B	36130661			He, H; Liu, Q; Chen, L; Wang, J; Yuan, Y; Li, H; Qian, X; Zhao, Z; Chen, Z	East China University of Science & Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=2579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=2579&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	STO	1AQ1,1BYG,1E8Z,1NVR,1NXK,1OKY,1Q3D,1QPD,1QPJ,1SM2,1SNU,1STC,1U59,1WVY,1XBC,1XJD,1YHS,2BUJ,2CLQ,2DQ7,2GCD,2HW7,2ITQ,2ITU,2ITW,2NRY,2OIC	44259	8032349	15738	CHEMBL388978		346	C02079	ZINC03814434	3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	1KXU,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	1UA2,6O9L,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,8BVW,8BYQ,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	1G25,6NMI,6O9L,6O9M,6TUN,6XBZ,6XD3,7B5O,7B5Q,7EGB,7EGC,7ENA,7ENC,7LBM,7NVR,7NVW,7NVX,7NVY,7NVZ,7NW0,8BVW,8BYQ	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415404	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OC3CCCC3O)n2)cc1	InChI=1S/C16H17N5O4S/c17-8-10-9-19-16(21-15(10)25-14-3-1-2-13(14)22)20-11-4-6-12(7-5-11)26(18,23)24/h4-7,9,13-14,22H,1-3H2,(H2,18,23,24)(H,19,20,21)	BFTPBRJJWBLTEE-UHFFFAOYSA-N	676262	US20240166635, Example 20a::US20240166635, Example 20b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676262&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171582037	500592026							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415410	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OC3CCCC3O)n2)cc1	InChI=1S/C16H17N5O4S/c17-8-10-9-19-16(21-15(10)25-14-3-1-2-13(14)22)20-11-4-6-12(7-5-11)26(18,23)24/h4-7,9,13-14,22H,1-3H2,(H2,18,23,24)(H,19,20,21)	BFTPBRJJWBLTEE-UHFFFAOYSA-N	676262	US20240166635, Example 20a::US20240166635, Example 20b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676262&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171582037	500592026							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415422	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OC3CCCCCC3O)n2)cc1	InChI=1S/C18H21N5O4S/c19-10-12-11-21-18(22-13-6-8-14(9-7-13)28(20,25)26)23-17(12)27-16-5-3-1-2-4-15(16)24/h6-9,11,15-16,24H,1-5H2,(H2,20,25,26)(H,21,22,23)	ITGDXSWIUCVGDW-UHFFFAOYSA-N	676268	US20240166635, Example 22a::US20240166635, Example 22b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676268&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090133	500592029							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415431	CC1(O)CCCC1Oc1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C#N	InChI=1S/C17H19N5O4S/c1-17(23)8-2-3-14(17)26-15-11(9-18)10-20-16(22-15)21-12-4-6-13(7-5-12)27(19,24)25/h4-7,10,14,23H,2-3,8H2,1H3,(H2,19,24,25)(H,20,21,22)	VBLLOFSUFOWCAN-UHFFFAOYSA-N	676270	US20240166635, Example 23a::US20240166635, Example 23b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676270&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090136	500592030							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415440	CC1(O)CCCCC1Oc1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C#N	InChI=1S/C18H21N5O4S/c1-18(24)9-3-2-4-15(18)27-16-12(10-19)11-21-17(23-16)22-13-5-7-14(8-6-13)28(20,25)26/h5-8,11,15,24H,2-4,9H2,1H3,(H2,20,25,26)(H,21,22,23)	DIWKEQSDYXLOJZ-UHFFFAOYSA-N	676276	US20240166635, Example 24a::US20240166635, Example 24b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<10							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676276	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676276&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089958	500592035							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416101	NS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCCCCC3O)n2)C(F)(F)F)cc1	InChI=1S/C18H21F3N4O4S/c19-18(20,21)13-10-23-17(24-11-6-8-12(9-7-11)30(22,27)28)25-16(13)29-15-5-3-1-2-4-14(15)26/h6-10,14-15,26H,1-5H2,(H2,22,27,28)(H,23,24,25)	BHEVXPKVRPTJTA-UHFFFAOYSA-N	676418	US20240166635, Example 118a::US20240166635, Example 118b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676418&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090127	500592135							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416110	CS(=O)(=O)C1CCC(CC1)Nc1ncc(c(OC2CCCC2O)n1)C(F)(F)F	InChI=1S/C17H24F3N3O4S/c1-28(25,26)11-7-5-10(6-8-11)22-16-21-9-12(17(18,19)20)15(23-16)27-14-4-2-3-13(14)24/h9-11,13-14,24H,2-8H2,1H3,(H,21,22,23)	KTSBBQZIUKTLBK-UHFFFAOYSA-N	676420	US20240166635, Example 119a::US20240166635, Example 119b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676420&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171581948	500592136							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416116	CS(=O)(=O)C1CCC(CC1)Nc1ncc(c(OC2CCCC2O)n1)C(F)(F)F	InChI=1S/C17H24F3N3O4S/c1-28(25,26)11-7-5-10(6-8-11)22-16-21-9-12(17(18,19)20)15(23-16)27-14-4-2-3-13(14)24/h9-11,13-14,24H,2-8H2,1H3,(H,21,22,23)	KTSBBQZIUKTLBK-UHFFFAOYSA-N	676420	US20240166635, Example 119a::US20240166635, Example 119b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676420&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171581948	500592136							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416122	CS(=O)(=O)N1CCC(CC1)Nc1ncc(c(OC2CCCCC2O)n1)C(F)(F)F	InChI=1S/C17H25F3N4O4S/c1-29(26,27)24-8-6-11(7-9-24)22-16-21-10-12(17(18,19)20)15(23-16)28-14-5-3-2-4-13(14)25/h10-11,13-14,25H,2-9H2,1H3,(H,21,22,23)	LLJFUISHLUDNSH-UHFFFAOYSA-N	676422	US20240166635, Example 120a::US20240166635, Example 120b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676422&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090158	500592137							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416131	CS(=O)(=O)N1CCC(CC1)Nc1ncc(c(OC2CCCCCC2O)n1)C(F)(F)F	InChI=1S/C18H27F3N4O4S/c1-30(27,28)25-9-7-12(8-10-25)23-17-22-11-13(18(19,20)21)16(24-17)29-15-6-4-2-3-5-14(15)26/h11-12,14-15,26H,2-10H2,1H3,(H,22,23,24)	ITKOZHPPZHBFOM-UHFFFAOYSA-N	676424	US20240166635, Example 121a::US20240166635, Example 121b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676424&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090100	500592138							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416143	NS(=O)(=O)N1CCC(CC1)Nc1ncc(c(OC2CCCCCC2O)n1)C(F)(F)F	InChI=1S/C17H26F3N5O4S/c18-17(19,20)12-10-22-16(23-11-6-8-25(9-7-11)30(21,27)28)24-15(12)29-14-5-3-1-2-4-13(14)26/h10-11,13-14,26H,1-9H2,(H2,21,27,28)(H,22,23,24)	LJAFGINNHCYOKR-UHFFFAOYSA-N	676426	US20240166635, Example 122a::US20240166635, Example 122b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676426&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090101	500592139							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415449	O[C@@H]1CCCC1Oc1nc(Nc2ccc(cc2)S(=O)(=O)NC2CCC2)ncc1C#N	InChI=1S/C20H23N5O4S/c21-11-13-12-22-20(24-19(13)29-18-6-2-5-17(18)26)23-14-7-9-16(10-8-14)30(27,28)25-15-3-1-4-15/h7-10,12,15,17-18,25-26H,1-6H2,(H,22,23,24)/t17-,18?/m1/s1	CPYMMHGVBXHMBP-QNSVNVJESA-N	676278	US20240166635, Example 25	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676278	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676278&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089959	500592036							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415455	CNS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OC3CCC[C@H]3O)n2)cc1	InChI=1S/C17H19N5O4S/c1-19-27(24,25)13-7-5-12(6-8-13)21-17-20-10-11(9-18)16(22-17)26-15-4-2-3-14(15)23/h5-8,10,14-15,19,23H,2-4H2,1H3,(H,20,21,22)/t14-,15?/m1/s1	HCBVVIFOIUAUCN-GICMACPYSA-N	676279	US20240166635, Example 26	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676279&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090307	500592037							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415461	CC(C)NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OC3CCC[C@H]3O)n2)cc1	InChI=1S/C19H23N5O4S/c1-12(2)24-29(26,27)15-8-6-14(7-9-15)22-19-21-11-13(10-20)18(23-19)28-17-5-3-4-16(17)25/h6-9,11-12,16-17,24-25H,3-5H2,1-2H3,(H,21,22,23)/t16-,17?/m1/s1	ROCHEUVEICUFRE-TZHYSIJRSA-N	676281	US20240166635, Example 27	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676281&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090302	500592039							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415482	OC1CCCCC1Oc1nc(Nc2ccc(cc2)S(=O)(=O)NC2C[C@H](F)C2)ncc1C#N	InChI=1S/C21H24FN5O4S/c22-14-9-16(10-14)27-32(29,30)17-7-5-15(6-8-17)25-21-24-12-13(11-23)20(26-21)31-19-4-2-1-3-18(19)28/h5-8,12,14,16,18-19,27-28H,1-4,9-10H2,(H,24,25,26)/t14-,16?,18?,19?	XSIFVBNGGAAWSP-MPCHACMSSA-N	676287	US20240166635, Example 31a::US20240166635, Example 31b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676287&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990654	500592043							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416152	CNS(=O)(=O)N1CCC(CC1)Nc1ncc(c(OC2CCCCCC2O)n1)C(F)(F)F	InChI=1S/C18H28F3N5O4S/c1-22-31(28,29)26-9-7-12(8-10-26)24-17-23-11-13(18(19,20)21)16(25-17)30-15-6-4-2-3-5-14(15)27/h11-12,14-15,22,27H,2-10H2,1H3,(H,23,24,25)	LNWDZMBWOAKXFT-UHFFFAOYSA-N	676428	US20240166635, Example 123a::US20240166635, Example 123b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676428&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089970	500592140							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416158	CC1(O)COCCC1Oc1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C(F)(F)F	InChI=1S/C17H25F3N4O5S/c1-16(25)10-28-8-5-13(16)29-14-12(17(18,19)20)9-21-15(23-14)22-11-3-6-24(7-4-11)30(2,26)27/h9,11,13,25H,3-8,10H2,1-2H3,(H,21,22,23)	MGXMGVUPCOMEOS-UHFFFAOYSA-N	676430	US20240166635, Example 124a::US20240166635, Example 124b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<10							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676430&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090359	500592141							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416169	Cn1cc(cn1)S(=O)(=O)N1CCC(CC1)Nc1ncc(c(OC2CCOCC2(C)O)n1)C(F)(F)F	InChI=1S/C20H27F3N6O5S/c1-19(30)12-33-8-5-16(19)34-17-15(20(21,22)23)10-24-18(27-17)26-13-3-6-29(7-4-13)35(31,32)14-9-25-28(2)11-14/h9-11,13,16,30H,3-8,12H2,1-2H3,(H,24,26,27)	KXDROPRNEYFQHH-UHFFFAOYSA-N	676432	US20240166635, Example 125a::US20240166635, Example 125b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<10							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676432&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090017	500592142							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416174	Cn1cc(cn1)S(=O)(=O)N1CCC(CC1)Nc1ncc(c(OC2CCOCC2(C)O)n1)C(F)(F)F	InChI=1S/C20H27F3N6O5S/c1-19(30)12-33-8-5-16(19)34-17-15(20(21,22)23)10-24-18(27-17)26-13-3-6-29(7-4-13)35(31,32)14-9-25-28(2)11-14/h9-11,13,16,30H,3-8,12H2,1-2H3,(H,24,26,27)	KXDROPRNEYFQHH-UHFFFAOYSA-N	676432	US20240166635, Example 125a::US20240166635, Example 125b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676432&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090017	500592142							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416179	CS(=O)(=O)N1CCC(CC1)Nc1ncc(c(OC2CCC2)n1)C(F)(F)F	InChI=1S/C15H21F3N4O3S/c1-26(23,24)22-7-5-10(6-8-22)20-14-19-9-12(15(16,17)18)13(21-14)25-11-3-2-4-11/h9-11H,2-8H2,1H3,(H,19,20,21)	PURBWBJEHYPPFZ-UHFFFAOYSA-N	676434	US20240166635, Example 126	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676434&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090223	500592143							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416185	CS(=O)(=O)N1CCC(CC1)Nc1ncc(c(OC2CCCCC2)n1)C(F)(F)F	InChI=1S/C17H25F3N4O3S/c1-28(25,26)24-9-7-12(8-10-24)22-16-21-11-14(17(18,19)20)15(23-16)27-13-5-3-2-4-6-13/h11-13H,2-10H2,1H3,(H,21,22,23)	SXBXSQCRXJFCCE-UHFFFAOYSA-N	676435	US20240166635, Example 127	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676435&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090220	500592144							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415491	OC1CCCCC1Oc1nc(Nc2ccc(cc2)S(=O)(=O)NC2CC(F)C2)ncc1C#N	InChI=1S/C21H24FN5O4S/c22-14-9-16(10-14)27-32(29,30)17-7-5-15(6-8-17)25-21-24-12-13(11-23)20(26-21)31-19-4-2-1-3-18(19)28/h5-8,12,14,16,18-19,27-28H,1-4,9-10H2,(H,24,25,26)	XSIFVBNGGAAWSP-UHFFFAOYSA-N	676289	US20240166635, Example 32a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676289&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990654	500592044							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415500	CNS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OC3CCCOCC3)n2)cc1	InChI=1S/C18H21N5O4S/c1-20-28(24,25)16-6-4-14(5-7-16)22-18-21-12-13(11-19)17(23-18)27-15-3-2-9-26-10-8-15/h4-7,12,15,20H,2-3,8-10H2,1H3,(H,21,22,23)	LYXRABIWUDHHOT-UHFFFAOYSA-N	676291	US20240166635, Example 33a::US20240166635, Example 33b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676291&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990655	500592046							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415509	CNS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OC3CCCC3(C)O)n2)cc1	InChI=1S/C18H21N5O4S/c1-18(24)9-3-4-15(18)27-16-12(10-19)11-21-17(23-16)22-13-5-7-14(8-6-13)28(25,26)20-2/h5-8,11,15,20,24H,3-4,9H2,1-2H3,(H,21,22,23)	QMXSDPDZRQFBHB-UHFFFAOYSA-N	676293	US20240166635, Example 34a::US20240166635, Example 34b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676293&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090173	500592047							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415518	CC(C)NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OC3CCCC3(C)O)n2)cc1	InChI=1S/C20H25N5O4S/c1-13(2)25-30(27,28)16-8-6-15(7-9-16)23-19-22-12-14(11-21)18(24-19)29-17-5-4-10-20(17,3)26/h6-9,12-13,17,25-26H,4-5,10H2,1-3H3,(H,22,23,24)	KGLRDVBOUHMCJQ-UHFFFAOYSA-N	676295	US20240166635, Example 35a::US20240166635, Example 35b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676295&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089955	500592048							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415530	CCS(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OC2CCCC2(C)O)n1	InChI=1S/C18H27N5O4S/c1-3-28(25,26)23-9-6-14(7-10-23)21-17-20-12-13(11-19)16(22-17)27-15-5-4-8-18(15,2)24/h12,14-15,24H,3-10H2,1-2H3,(H,20,21,22)	YOHCMXQAXUTESC-UHFFFAOYSA-N	676297	US20240166635, Example 36a::US20240166635, Example 36b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676297	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676297&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090011	500592049							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416191	CC1(COc2nc(NC3CCN(CC3)S(C)(=O)=O)ncc2C(F)(F)F)CCCC1	InChI=1S/C18H27F3N4O3S/c1-17(7-3-4-8-17)12-28-15-14(18(19,20)21)11-22-16(24-15)23-13-5-9-25(10-6-13)29(2,26)27/h11,13H,3-10,12H2,1-2H3,(H,22,23,24)	PFPUFIQGDNYBND-UHFFFAOYSA-N	676436	US20240166635, Example 128	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676436&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090222	500592145							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416197	CNS(=O)(=O)N1CCC(CC1)Nc1ncc(c(OC2CCCCCC2)n1)C(F)(F)F	InChI=1S/C18H28F3N5O3S/c1-22-30(27,28)26-10-8-13(9-11-26)24-17-23-12-15(18(19,20)21)16(25-17)29-14-6-4-2-3-5-7-14/h12-14,22H,2-11H2,1H3,(H,23,24,25)	CXABQNFLIBANJT-UHFFFAOYSA-N	676437	US20240166635, Example 129	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676437&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090107	500592146							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416203	O[C@@H]1CCC[C@@H]1Oc1nc(Nc2ccc(cc2)S(=O)(=O)NC2CCOCC2)ncc1Cl	InChI=1S/C20H25ClN4O5S/c21-16-12-22-20(24-19(16)30-18-3-1-2-17(18)26)23-13-4-6-15(7-5-13)31(27,28)25-14-8-10-29-11-9-14/h4-7,12,14,17-18,25-26H,1-3,8-11H2,(H,22,23,24)/t17-,18+/m1/s1	VRFZDEOOGRCBHS-MSOLQXFVSA-N	676438	US20240166635, Example 130a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676438&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090076	500592147							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416212	CC1(COC1)NS(=O)(=O)c1ccc(Nc2ncc(Br)c(O[C@H]3CCC[C@H]3O)n2)cc1	InChI=1S/C19H23BrN4O5S/c1-19(10-28-11-19)24-30(26,27)13-7-5-12(6-8-13)22-18-21-9-14(20)17(23-18)29-16-4-2-3-15(16)25/h5-9,15-16,24-25H,2-4,10-11H2,1H3,(H,21,22,23)/t15-,16+/m1/s1	UPTWBJNAWIDIOT-CVEARBPZSA-N	676440	US20240166635, Example 131a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676440&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090230	500592149							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416221	Cc1cnc(Nc2ccc(cc2)S(N)(=O)=O)nc1O[C@H]1CCC[C@H]1O	InChI=1S/C16H20N4O4S/c1-10-9-18-16(20-15(10)24-14-4-2-3-13(14)21)19-11-5-7-12(8-6-11)25(17,22)23/h5-9,13-14,21H,2-4H2,1H3,(H2,17,22,23)(H,18,19,20)/t13-,14+/m1/s1	UGHLOFSFUSXPNA-KGLIPLIRSA-N	676442	US20240166635, Example 132a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676442	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676442&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089951	500592151							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416230	CCc1cnc(Nc2ccc(cc2)S(N)(=O)=O)nc1O[C@H]1CCC[C@H]1O	InChI=1S/C17H22N4O4S/c1-2-11-10-19-17(21-16(11)25-15-5-3-4-14(15)22)20-12-6-8-13(9-7-12)26(18,23)24/h6-10,14-15,22H,2-5H2,1H3,(H2,18,23,24)(H,19,20,21)/t14-,15+/m1/s1	JADLERCCPNPQHG-CABCVRRESA-N	676444	US20240166635, Example 133a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676444&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090028	500592153							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415536	CC1(O)CCCC1Oc1nc(NC2CCN(CC2)S(=O)(=O)CF)ncc1C#N	InChI=1S/C17H24FN5O4S/c1-17(24)6-2-3-14(17)27-15-12(9-19)10-20-16(22-15)21-13-4-7-23(8-5-13)28(25,26)11-18/h10,13-14,24H,2-8,11H2,1H3,(H,20,21,22)	IVURPCHRYKNZNK-UHFFFAOYSA-N	676299	US20240166635, Example 37a::US20240166635, Example 37b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676299&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090012	500592050							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415545	CC1(O)CCCC1Oc1nc(NC2CCN(CC2)S(=O)(=O)CC2CC2)ncc1C#N	InChI=1S/C20H29N5O4S/c1-20(26)8-2-3-17(20)29-18-15(11-21)12-22-19(24-18)23-16-6-9-25(10-7-16)30(27,28)13-14-4-5-14/h12,14,16-17,26H,2-10,13H2,1H3,(H,22,23,24)	RFQTYMYGZAUINI-UHFFFAOYSA-N	676301	US20240166635, Example 38a::US20240166635, Example 38b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676301&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090103	500592051							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415554	CC(C)CS(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OC2CCCC2(C)O)n1	InChI=1S/C20H31N5O4S/c1-14(2)13-30(27,28)25-9-6-16(7-10-25)23-19-22-12-15(11-21)18(24-19)29-17-5-4-8-20(17,3)26/h12,14,16-17,26H,4-10,13H2,1-3H3,(H,22,23,24)	MTDAFJHVIZBORH-UHFFFAOYSA-N	676303	US20240166635, Example 39a::US20240166635, Example 39b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676303&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171582096	500592052							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415563	CC1(O)CCCC1Oc1nc(NC2CCN(CC2)S(=O)(=O)CC2CCOC2)ncc1C#N	InChI=1S/C21H31N5O5S/c1-21(27)7-2-3-18(21)31-19-16(11-22)12-23-20(25-19)24-17-4-8-26(9-5-17)32(28,29)14-15-6-10-30-13-15/h12,15,17-18,27H,2-10,13-14H2,1H3,(H,23,24,25)	KBKJXHHYCYMRHQ-UHFFFAOYSA-N	676305	US20240166635, Example 40a::US20240166635, Example 40b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676305&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090175	500592053							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415568	CC1(O)CCCC1Oc1nc(NC2CCN(CC2)S(=O)(=O)CC2CCOC2)ncc1C#N	InChI=1S/C21H31N5O5S/c1-21(27)7-2-3-18(21)31-19-16(11-22)12-23-20(25-19)24-17-4-8-26(9-5-17)32(28,29)14-15-6-10-30-13-15/h12,15,17-18,27H,2-10,13-14H2,1H3,(H,23,24,25)	KBKJXHHYCYMRHQ-UHFFFAOYSA-N	676305	US20240166635, Example 40a::US20240166635, Example 40b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676305&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090175	500592053							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415573	COCCS(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OC2CCCC2(C)O)n1	InChI=1S/C19H29N5O5S/c1-19(25)7-3-4-16(19)29-17-14(12-20)13-21-18(23-17)22-15-5-8-24(9-6-15)30(26,27)11-10-28-2/h13,15-16,25H,3-11H2,1-2H3,(H,21,22,23)	WNPAEAQXLNHGQL-UHFFFAOYSA-N	676307	US20240166635, Example 41a::US20240166635, Example 41b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676307&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090099	500592054							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416239	CC(C)NS(=O)(=O)c1ccc(Nc2ncc(C3CC3)c(O[C@H]3CCC[C@H]3O)n2)cc1	InChI=1S/C21H28N4O4S/c1-13(2)25-30(27,28)16-10-8-15(9-11-16)23-21-22-12-17(14-6-7-14)20(24-21)29-19-5-3-4-18(19)26/h8-14,18-19,25-26H,3-7H2,1-2H3,(H,22,23,24)/t18-,19+/m1/s1	RXQUQZRKAFSXQT-MOPGFXCFSA-N	676446	US20240166635, Example 134a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676446&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			169915556	500592155							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416248	CNS(=O)(=O)c1ccc(Nc2ncc(C(F)=C)c(O[C@H]3CCC[C@H]3O)n2)cc1	InChI=1S/C18H21FN4O4S/c1-11(19)14-10-21-18(23-17(14)27-16-5-3-4-15(16)24)22-12-6-8-13(9-7-12)28(25,26)20-2/h6-10,15-16,20,24H,1,3-5H2,2H3,(H,21,22,23)/t15-,16+/m1/s1	QXSFFHMNHMKKGS-CVEARBPZSA-N	676448	US20240166635, Example 135a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676448	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676448&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990672	500592157							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416257	NS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCCC3O)n2)C(F)(F)F)cc1	InChI=1S/C16H17F3N4O4S/c17-16(18,19)11-8-21-15(23-14(11)27-13-3-1-2-12(13)24)22-9-4-6-10(7-5-9)28(20,25)26/h4-8,12-13,24H,1-3H2,(H2,20,25,26)(H,21,22,23)	ALDIKYMFXCVIAW-UHFFFAOYSA-N	676450	US20240166635, Example 136a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676450	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676450&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089954	500592159							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416266	CNS(=O)(=O)c1ccc(Nc2ncc(Cl)c(OC3CCCC3O)n2)cc1	InChI=1S/C16H19ClN4O4S/c1-18-26(23,24)11-7-5-10(6-8-11)20-16-19-9-12(17)15(21-16)25-14-4-2-3-13(14)22/h5-9,13-14,18,22H,2-4H2,1H3,(H,19,20,21)	QWNPBVNMKNDQGI-UHFFFAOYSA-N	676452	US20240166635, Example 137a::US20240166635, Example 137b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676452&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090201	500592161							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416275	CC(C)NS(=O)(=O)c1ccc(Nc2ncc(Cl)c(OC3CCCC3O)n2)cc1	InChI=1S/C18H23ClN4O4S/c1-11(2)23-28(25,26)13-8-6-12(7-9-13)21-18-20-10-14(19)17(22-18)27-16-5-3-4-15(16)24/h6-11,15-16,23-24H,3-5H2,1-2H3,(H,20,21,22)	PMWBBNBMWPQOEF-UHFFFAOYSA-N	676454	US20240166635, Example 138a::US20240166635, Example 138b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676454	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676454&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090010	500592162							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415583	CC1(O)CCCC1Oc1nc(NC2CCN(CC2)S(=O)(=O)C(F)(F)F)ncc1C#N	InChI=1S/C17H22F3N5O4S/c1-16(26)6-2-3-13(16)29-14-11(9-21)10-22-15(24-14)23-12-4-7-25(8-5-12)30(27,28)17(18,19)20/h10,12-13,26H,2-8H2,1H3,(H,22,23,24)	NYDBQVDGDFSUFN-UHFFFAOYSA-N	676309	US20240166635, Example 42a::US20240166635, Example 42b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676309&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171581921	500592055							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415587	CC1(O)CCCC1Oc1nc(NC2CCN(CC2)S(=O)(=O)C(F)(F)F)ncc1C#N	InChI=1S/C17H22F3N5O4S/c1-16(26)6-2-3-13(16)29-14-11(9-21)10-22-15(24-14)23-12-4-7-25(8-5-12)30(27,28)17(18,19)20/h10,12-13,26H,2-8H2,1H3,(H,22,23,24)	NYDBQVDGDFSUFN-UHFFFAOYSA-N	676309	US20240166635, Example 42a::US20240166635, Example 42b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676309&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171581921	500592055							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415592	CC1(O)CCCC1Oc1nc(NC2CCN(CC2)S(=O)(=O)CC(F)(F)F)ncc1C#N	InChI=1S/C18H24F3N5O4S/c1-17(27)6-2-3-14(17)30-15-12(9-22)10-23-16(25-15)24-13-4-7-26(8-5-13)31(28,29)11-18(19,20)21/h10,13-14,27H,2-8,11H2,1H3,(H,23,24,25)	TXBBMRZBMVLLAQ-UHFFFAOYSA-N	676311	US20240166635, Example 43a::US20240166635, Example 43b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676311&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090053	500592056							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415597	CC1(O)CCCC1Oc1nc(NC2CCN(CC2)S(=O)(=O)CC(F)(F)F)ncc1C#N	InChI=1S/C18H24F3N5O4S/c1-17(27)6-2-3-14(17)30-15-12(9-22)10-23-16(25-15)24-13-4-7-26(8-5-13)31(28,29)11-18(19,20)21/h10,13-14,27H,2-8,11H2,1H3,(H,23,24,25)	TXBBMRZBMVLLAQ-UHFFFAOYSA-N	676311	US20240166635, Example 43a::US20240166635, Example 43b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676311&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090053	500592056							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415607	CC1(O)CC(F)(F)CC1Oc1nc(NC2CCN(CC2)S(=O)(=O)CC2CC2)ncc1C#N	InChI=1S/C20H27F2N5O4S/c1-19(28)12-20(21,22)8-16(19)31-17-14(9-23)10-24-18(26-17)25-15-4-6-27(7-5-15)32(29,30)11-13-2-3-13/h10,13,15-16,28H,2-8,11-12H2,1H3,(H,24,25,26)	UAAXTVOYMWPDBQ-UHFFFAOYSA-N	676313	US20240166635, Example 44a::US20240166635, Example 44b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676313&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090055	500592057							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415613	CC1(O)COCCC1Oc1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C#N	InChI=1S/C17H25N5O5S/c1-17(23)11-26-8-5-14(17)27-15-12(9-18)10-19-16(21-15)20-13-3-6-22(7-4-13)28(2,24)25/h10,13-14,23H,3-8,11H2,1-2H3,(H,19,20,21)	KXJILSLZMSOTHK-UHFFFAOYSA-N	676315	US20240166635, Example 45a::US20240166635, Example 45b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676315	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676315&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090344	500592058							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416284	CN1CCC(CC1)NS(=O)(=O)c1ccc(Nc2ncc(Cl)c(OC3CCCC3O)n2)cc1	InChI=1S/C21H28ClN5O4S/c1-27-11-9-15(10-12-27)26-32(29,30)16-7-5-14(6-8-16)24-21-23-13-17(22)20(25-21)31-19-4-2-3-18(19)28/h5-8,13,15,18-19,26,28H,2-4,9-12H2,1H3,(H,23,24,25)	IXDIKQYUVPRTQH-UHFFFAOYSA-N	676456	US20240166635, Example 139a::US20240166635, Example 139b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676456	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676456&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090026	500592163							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416290	CN1CCC(CC1)NS(=O)(=O)c1ccc(Nc2ncc(Cl)c(OC3CCCC3O)n2)cc1	InChI=1S/C21H28ClN5O4S/c1-27-11-9-15(10-12-27)26-32(29,30)16-7-5-14(6-8-16)24-21-23-13-17(22)20(25-21)31-19-4-2-3-18(19)28/h5-8,13,15,18-19,26,28H,2-4,9-12H2,1H3,(H,23,24,25)	IXDIKQYUVPRTQH-UHFFFAOYSA-N	676456	US20240166635, Example 139a::US20240166635, Example 139b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676456	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676456&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090026	500592163							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416296	CNS(=O)(=O)c1ccc(Nc2ncc(Cl)c(OC3COCC3(C)O)n2)cc1	InChI=1S/C16H19ClN4O5S/c1-16(22)9-25-8-13(16)26-14-12(17)7-19-15(21-14)20-10-3-5-11(6-4-10)27(23,24)18-2/h3-7,13,18,22H,8-9H2,1-2H3,(H,19,20,21)	MCVYLHWRTAZNNE-UHFFFAOYSA-N	676458	US20240166635, Example 140a::US20240166635, Example 140b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676458	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676458&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990674	500592164							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416305	NS(=O)(=O)c1ccc(Nc2ncc(Br)c(OC3CCCC3O)n2)cc1	InChI=1S/C15H17BrN4O4S/c16-11-8-18-15(20-14(11)24-13-3-1-2-12(13)21)19-9-4-6-10(7-5-9)25(17,22)23/h4-8,12-13,21H,1-3H2,(H2,17,22,23)(H,18,19,20)	FPCYLEFUNFBEOV-UHFFFAOYSA-N	676460	US20240166635, Example 141a::US20240166635, Example 141b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676460&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090029	500592165							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416314	CNS(=O)(=O)c1ccc(Nc2ncc(Br)c(OC3CCCC3O)n2)cc1	InChI=1S/C16H19BrN4O4S/c1-18-26(23,24)11-7-5-10(6-8-11)20-16-19-9-12(17)15(21-16)25-14-4-2-3-13(14)22/h5-9,13-14,18,22H,2-4H2,1H3,(H,19,20,21)	NHBKBNJTRGHNMQ-UHFFFAOYSA-N	676462	US20240166635, Example 142a::US20240166635, Example 142b::US20240166635, Example 143a::US20240166635, Example 143b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676462	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676462&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090250	500592166							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415627	CC1(O)CCC(F)(F)CC1Oc1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C#N	InChI=1S/C18H25F2N5O4S/c1-17(26)5-6-18(19,20)9-14(17)29-15-12(10-21)11-22-16(24-15)23-13-3-7-25(8-4-13)30(2,27)28/h11,13-14,26H,3-9H2,1-2H3,(H,22,23,24)	YXQIJCZYWYSLMZ-UHFFFAOYSA-N	676317	US20240166635, Example 46a::US20240166635, Example 46b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		<10							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676317	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676317&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090343	500592059							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415633	CC1(O)CC(F)(F)CCC1Oc1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C#N	InChI=1S/C18H25F2N5O4S/c1-17(26)11-18(19,20)6-3-14(17)29-15-12(9-21)10-22-16(24-15)23-13-4-7-25(8-5-13)30(2,27)28/h10,13-14,26H,3-8,11H2,1-2H3,(H,22,23,24)	UAACCBHMQBQBIY-UHFFFAOYSA-N	676319	US20240166635, Example 47a::US20240166635, Example 47b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676319&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090342	500592060							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415639	CC1(O)CC(F)(F)CCC1Oc1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C#N	InChI=1S/C18H25F2N5O4S/c1-17(26)11-18(19,20)6-3-14(17)29-15-12(9-21)10-22-16(24-15)23-13-4-7-25(8-5-13)30(2,27)28/h10,13-14,26H,3-8,11H2,1-2H3,(H,22,23,24)	UAACCBHMQBQBIY-UHFFFAOYSA-N	676319	US20240166635, Example 47a::US20240166635, Example 47b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676319&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090342	500592060							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415645	Cn1cc(cn1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OC2CCCC2(C)O)n1	InChI=1S/C20H27N7O4S/c1-20(28)7-3-4-17(20)31-18-14(10-21)11-22-19(25-18)24-15-5-8-27(9-6-15)32(29,30)16-12-23-26(2)13-16/h11-13,15,17,28H,3-9H2,1-2H3,(H,22,24,25)	TYCIGEQMTDJQIM-UHFFFAOYSA-N	676321	US20240166635, Example 48a::US20240166635, Example 48b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676321	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676321&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090349	500592061							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415656	Cn1cc(cn1)S(=O)(=O)N1CCC(Nc2ncc(C#N)c(OC3CCCC3(C)O)n2)C(F)C1	InChI=1S/C20H26FN7O4S/c1-20(29)6-3-4-17(20)32-18-13(8-22)9-23-19(26-18)25-16-5-7-28(12-15(16)21)33(30,31)14-10-24-27(2)11-14/h9-11,15-17,29H,3-7,12H2,1-2H3,(H,23,25,26)	AIPDCXCWEXJHRH-UHFFFAOYSA-N	676323	US20240166635, Example 49a::US20240166635, Example 49b::US20240166635, Example 49c::US20240166635, Example 49d	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676323&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090234	500592062							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415661	Cn1cc(cn1)S(=O)(=O)N1CCC(Nc2ncc(C#N)c(OC3CCCC3(C)O)n2)C(F)C1	InChI=1S/C20H26FN7O4S/c1-20(29)6-3-4-17(20)32-18-13(8-22)9-23-19(26-18)25-16-5-7-28(12-15(16)21)33(30,31)14-10-24-27(2)11-14/h9-11,15-17,29H,3-7,12H2,1-2H3,(H,23,25,26)	AIPDCXCWEXJHRH-UHFFFAOYSA-N	676323	US20240166635, Example 49a::US20240166635, Example 49b::US20240166635, Example 49c::US20240166635, Example 49d	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676323&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090234	500592062							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416323	CNS(=O)(=O)c1ccc(Nc2ncc(Br)c(OC3CCCC3O)n2)cc1	InChI=1S/C16H19BrN4O4S/c1-18-26(23,24)11-7-5-10(6-8-11)20-16-19-9-12(17)15(21-16)25-14-4-2-3-13(14)22/h5-9,13-14,18,22H,2-4H2,1H3,(H,19,20,21)	NHBKBNJTRGHNMQ-UHFFFAOYSA-N	676462	US20240166635, Example 142a::US20240166635, Example 142b::US20240166635, Example 143a::US20240166635, Example 143b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676462	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676462&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090250	500592166							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416335	Cn1cc(cn1)S(=O)(=O)N1CCC(CC1)Nc1ncc(Br)c(OC2CCCCC2O)n1	InChI=1S/C19H27BrN6O4S/c1-25-12-14(10-22-25)31(28,29)26-8-6-13(7-9-26)23-19-21-11-15(20)18(24-19)30-17-5-3-2-4-16(17)27/h10-13,16-17,27H,2-9H2,1H3,(H,21,23,24)	VBTFDZNKWVGQPG-UHFFFAOYSA-N	676466	US20240166635, Example 144a::US20240166635, Example 144b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676466	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676466&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171581960	500592167							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416344	CS(=O)(=O)N1CCC(CC1)Nc1ncc(Br)c(OC2CCCCCC2O)n1	InChI=1S/C17H27BrN4O4S/c1-27(24,25)22-9-7-12(8-10-22)20-17-19-11-13(18)16(21-17)26-15-6-4-2-3-5-14(15)23/h11-12,14-15,23H,2-10H2,1H3,(H,19,20,21)	KNSBENBIJKAOTM-UHFFFAOYSA-N	676468	US20240166635, Example 145a::US20240166635, Example 145b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676468&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089967	500592168							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416350	Cc1cnc(Nc2ccc(cc2)S(=O)(=O)NC2CC2)nc1OC1CCCC1O	InChI=1S/C19H24N4O4S/c1-12-11-20-19(22-18(12)27-17-4-2-3-16(17)24)21-13-7-9-15(10-8-13)28(25,26)23-14-5-6-14/h7-11,14,16-17,23-24H,2-6H2,1H3,(H,20,21,22)	RCMDDAKHUFLBAQ-UHFFFAOYSA-N	676470	US20240166635, Example 146a::US20240166635, Example 146b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676470	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676470&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090088	500592169							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416359	CC(C)NS(=O)(=O)c1ccc(Nc2ncc(C)c(OC3CCCC3O)n2)cc1	InChI=1S/C19H26N4O4S/c1-12(2)23-28(25,26)15-9-7-14(8-10-15)21-19-20-11-13(3)18(22-19)27-17-6-4-5-16(17)24/h7-12,16-17,23-24H,4-6H2,1-3H3,(H,20,21,22)	HOISFQJJCQCQFV-UHFFFAOYSA-N	676472	US20240166635, Example 147a::US20240166635, Example 147b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676472&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990675	500592170							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415666	Cn1cc(cn1)S(=O)(=O)N1CCC(Nc2ncc(C#N)c(OC3CCCC3(C)O)n2)C(F)C1	InChI=1S/C20H26FN7O4S/c1-20(29)6-3-4-17(20)32-18-13(8-22)9-23-19(26-18)25-16-5-7-28(12-15(16)21)33(30,31)14-10-24-27(2)11-14/h9-11,15-17,29H,3-7,12H2,1-2H3,(H,23,25,26)	AIPDCXCWEXJHRH-UHFFFAOYSA-N	676323	US20240166635, Example 49a::US20240166635, Example 49b::US20240166635, Example 49c::US20240166635, Example 49d	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676323&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090234	500592062							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415670	Cn1cc(cn1)S(=O)(=O)N1CCC(Nc2ncc(C#N)c(OC3CCCC3(C)O)n2)C(F)C1	InChI=1S/C20H26FN7O4S/c1-20(29)6-3-4-17(20)32-18-13(8-22)9-23-19(26-18)25-16-5-7-28(12-15(16)21)33(30,31)14-10-24-27(2)11-14/h9-11,15-17,29H,3-7,12H2,1-2H3,(H,23,25,26)	AIPDCXCWEXJHRH-UHFFFAOYSA-N	676323	US20240166635, Example 49a::US20240166635, Example 49b::US20240166635, Example 49c::US20240166635, Example 49d	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676323&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090234	500592062							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415675	Cn1cnc(c1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OC2CCCC2(C)O)n1	InChI=1S/C20H27N7O4S/c1-20(28)7-3-4-16(20)31-18-14(10-21)11-22-19(25-18)24-15-5-8-27(9-6-15)32(29,30)17-12-26(2)13-23-17/h11-13,15-16,28H,3-9H2,1-2H3,(H,22,24,25)	QCBLVLKFDWENOV-UHFFFAOYSA-N	676327	US20240166635, Example 50a::US20240166635, Example 50b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676327	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676327&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090094	500592063							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415680	Cn1cnc(c1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OC2CCCC2(C)O)n1	InChI=1S/C20H27N7O4S/c1-20(28)7-3-4-16(20)31-18-14(10-21)11-22-19(25-18)24-15-5-8-27(9-6-15)32(29,30)17-12-26(2)13-23-17/h11-13,15-16,28H,3-9H2,1-2H3,(H,22,24,25)	QCBLVLKFDWENOV-UHFFFAOYSA-N	676327	US20240166635, Example 50a::US20240166635, Example 50b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676327	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676327&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090094	500592063							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415684	Cn1cnc(n1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OC2CCCC2(C)O)n1	InChI=1S/C19H26N8O4S/c1-19(28)7-3-4-15(19)31-16-13(10-20)11-21-17(24-16)23-14-5-8-27(9-6-14)32(29,30)18-22-12-26(2)25-18/h11-12,14-15,28H,3-9H2,1-2H3,(H,21,23,24)	WNYMMGOZYJKIQP-UHFFFAOYSA-N	676329	US20240166635, Example 51a::US20240166635, Example 51b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676329	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676329&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089946	500592064							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415688	Cn1cnc(n1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OC2CCCC2(C)O)n1	InChI=1S/C19H26N8O4S/c1-19(28)7-3-4-15(19)31-16-13(10-20)11-21-17(24-16)23-14-5-8-27(9-6-14)32(29,30)18-22-12-26(2)25-18/h11-12,14-15,28H,3-9H2,1-2H3,(H,21,23,24)	WNYMMGOZYJKIQP-UHFFFAOYSA-N	676329	US20240166635, Example 51a::US20240166635, Example 51b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676329	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676329&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089946	500592064							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415693	CS(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OC2CCCC2)n1	InChI=1S/C16H23N5O3S/c1-25(22,23)21-8-6-13(7-9-21)19-16-18-11-12(10-17)15(20-16)24-14-4-2-3-5-14/h11,13-14H,2-9H2,1H3,(H,18,19,20)	NFRIEKMTZDQPPU-UHFFFAOYSA-N	676331	US20240166635, Example 52	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676331	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676331&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			164855024	500592065							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415699	CC1(COc2nc(NC3CCN(CC3)S(C)(=O)=O)ncc2C#N)CCC1	InChI=1S/C17H25N5O3S/c1-17(6-3-7-17)12-25-15-13(10-18)11-19-16(21-15)20-14-4-8-22(9-5-14)26(2,23)24/h11,14H,3-9,12H2,1-2H3,(H,19,20,21)	IUGKQCKADAUULW-UHFFFAOYSA-N	676332	US20240166635, Example 53	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676332	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676332&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090308	500592066							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415705	CC1(COc2nc(NC3CCN(CC3)S(C)(=O)=O)ncc2C#N)CCCC1	InChI=1S/C18H27N5O3S/c1-18(7-3-4-8-18)13-26-16-14(11-19)12-20-17(22-16)21-15-5-9-23(10-6-15)27(2,24)25/h12,15H,3-10,13H2,1-2H3,(H,20,21,22)	JVBPIKUNIDNBCH-UHFFFAOYSA-N	676333	US20240166635, Example 54	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676333	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676333&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090305	500592067							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416368	CNS(=O)(=O)c1ccc(Nc2ncc(C)c(OC3CCCC3O)n2)cc1	InChI=1S/C17H22N4O4S/c1-11-10-19-17(21-16(11)25-15-5-3-4-14(15)22)20-12-6-8-13(9-7-12)26(23,24)18-2/h6-10,14-15,18,22H,3-5H2,1-2H3,(H,19,20,21)	OELWRYRKFMYGJW-UHFFFAOYSA-N	676474	US20240166635, Example 148a::US20240166635, Example 148b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676474&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990676	500592171							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416377	CCc1cnc(Nc2ccc(cc2)S(=O)(=O)NC)nc1OC1CCCC1O	InChI=1S/C18H24N4O4S/c1-3-12-11-20-18(22-17(12)26-16-6-4-5-15(16)23)21-13-7-9-14(10-8-13)27(24,25)19-2/h7-11,15-16,19,23H,3-6H2,1-2H3,(H,20,21,22)	SKHNNUOJRNSIFG-UHFFFAOYSA-N	676476	US20240166635, Example 149a::US20240166635, Example 149b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676476&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990677	500592172							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416386	CCc1cnc(Nc2ccc(cc2)S(=O)(=O)NC)nc1OC1COCC1(C)O	InChI=1S/C18H24N4O5S/c1-4-12-9-20-17(22-16(12)27-15-10-26-11-18(15,2)23)21-13-5-7-14(8-6-13)28(24,25)19-3/h5-9,15,19,23H,4,10-11H2,1-3H3,(H,20,21,22)	ZYIUATVXCNVESH-UHFFFAOYSA-N	676478	US20240166635, Example 150a::US20240166635, Example 150b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676478&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990678	500592173							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416394	CCc1cnc(Nc2ccc(cc2)S(=O)(=O)NC)nc1OC1CCOCC1O	InChI=1S/C18H24N4O5S/c1-3-12-10-20-18(22-17(12)27-16-8-9-26-11-15(16)23)21-13-4-6-14(7-5-13)28(24,25)19-2/h4-7,10,15-16,19,23H,3,8-9,11H2,1-2H3,(H,20,21,22)	WEPISGPURNHABS-UHFFFAOYSA-N	676480	US20240166635, Example 151a::US20240166635, Example 151b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676480&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990679	500592174							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415711	CNS(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OCC2(C)CCCC2)n1	InChI=1S/C18H28N6O3S/c1-18(7-3-4-8-18)13-27-16-14(11-19)12-21-17(23-16)22-15-5-9-24(10-6-15)28(25,26)20-2/h12,15,20H,3-10,13H2,1-2H3,(H,21,22,23)	RTOZTQPNHKYMFF-UHFFFAOYSA-N	676334	US20240166635, Example 55	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676334	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676334&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089916	500592068							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415717	CC1(COc2nc(NC3CCN(CC3)S(N)(=O)=O)ncc2C#N)CCCC1	InChI=1S/C17H26N6O3S/c1-17(6-2-3-7-17)12-26-15-13(10-18)11-20-16(22-15)21-14-4-8-23(9-5-14)27(19,24)25/h11,14H,2-9,12H2,1H3,(H2,19,24,25)(H,20,21,22)	WGPONUKJUHDRKT-UHFFFAOYSA-N	676335	US20240166635, Example 56	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676335	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676335&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089921	500592069							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415723	CC1(COc2nc(NC3CCN(CC3)S(=O)(=O)CCO)ncc2C#N)CCCC1	InChI=1S/C19H29N5O4S/c1-19(6-2-3-7-19)14-28-17-15(12-20)13-21-18(23-17)22-16-4-8-24(9-5-16)29(26,27)11-10-25/h13,16,25H,2-11,14H2,1H3,(H,21,22,23)	TUWIDIPOQFITJN-UHFFFAOYSA-N	676336	US20240166635, Example 57	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676336&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089917	500592070							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415729	COCCS(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OCC2(C)CCCC2)n1	InChI=1S/C20H31N5O4S/c1-20(7-3-4-8-20)15-29-18-16(13-21)14-22-19(24-18)23-17-5-9-25(10-6-17)30(26,27)12-11-28-2/h14,17H,3-12,15H2,1-2H3,(H,22,23,24)	JZYAYXLXBYQUJR-UHFFFAOYSA-N	676337	US20240166635, Example 58	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676337	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676337&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089924	500592071							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415735	Cn1cc(cn1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OC2CC3(CCC3)C2)n1	InChI=1S/C21H27N7O3S/c1-27-14-18(13-24-27)32(29,30)28-7-3-16(4-8-28)25-20-23-12-15(11-22)19(26-20)31-17-9-21(10-17)5-2-6-21/h12-14,16-17H,2-10H2,1H3,(H,23,25,26)	JJTOOCRKQWDIDD-UHFFFAOYSA-N	676338	US20240166635, Example 59	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676338	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676338&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171581906	500592072							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415741	Cn1cc(cn1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OCC2(C)CCC2)n1	InChI=1S/C20H27N7O3S/c1-20(6-3-7-20)14-30-18-15(10-21)11-22-19(25-18)24-16-4-8-27(9-5-16)31(28,29)17-12-23-26(2)13-17/h11-13,16H,3-9,14H2,1-2H3,(H,22,24,25)	ONSDZEZFRFUDNV-UHFFFAOYSA-N	676339	US20240166635, Example 60	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676339	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676339&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089923	500592073							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415747	Cn1cc(cn1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OCC2(C)CC(F)(F)C2)n1	InChI=1S/C20H25F2N7O3S/c1-19(11-20(21,22)12-19)13-32-17-14(7-23)8-24-18(27-17)26-15-3-5-29(6-4-15)33(30,31)16-9-25-28(2)10-16/h8-10,15H,3-6,11-13H2,1-2H3,(H,24,26,27)	QUWHYVIAUBWWFO-UHFFFAOYSA-N	676340	US20240166635, Example 61	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676340&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171582026	500592074							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415753	Cn1cc(cn1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OCC2(C)CCCC2)n1	InChI=1S/C21H29N7O3S/c1-21(7-3-4-8-21)15-31-19-16(11-22)12-23-20(26-19)25-17-5-9-28(10-6-17)32(29,30)18-13-24-27(2)14-18/h12-14,17H,3-10,15H2,1-2H3,(H,23,25,26)	MXLQXNPUTMMXQE-UHFFFAOYSA-N	676341	US20240166635, Example 62	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676341&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089922	500592075							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415859	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)N2CCCC(C2)c2ccccc2)cc1	InChI=1S/C22H22N6O2S/c23-13-18-14-25-22(26-19-8-10-20(11-9-19)31(24,29)30)27-21(18)28-12-4-7-17(15-28)16-5-2-1-3-6-16/h1-3,5-6,8-11,14,17H,4,7,12,15H2,(H2,24,29,30)(H,25,26,27)	DUAHUWZSSCBNCQ-UHFFFAOYSA-N	676364	US20240166635, Example 84::US20240166635, Example 85	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676364&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090154	500592098							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415864	NS(=O)(=O)c1ccc(Nc2ncc(F)c(n2)N2CCCCC2)cc1	InChI=1S/C15H18FN5O2S/c16-13-10-18-15(20-14(13)21-8-2-1-3-9-21)19-11-4-6-12(7-5-11)24(17,22)23/h4-7,10H,1-3,8-9H2,(H2,17,22,23)(H,18,19,20)	FTJDGUPVEVBZFA-UHFFFAOYSA-N	676366	US20240166635, Example 86	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676366	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676366&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090155	500592099							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415872	CS(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(n1)N1CCCCC1	InChI=1S/C16H24N6O2S/c1-25(23,24)22-9-5-14(6-10-22)19-16-18-12-13(11-17)15(20-16)21-7-3-2-4-8-21/h12,14H,2-10H2,1H3,(H,18,19,20)	OCARTNNFCDDTMN-UHFFFAOYSA-N	676369	US20240166635, Example 89	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676369	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676369&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090298	500592102							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415880	CNS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)N2CCCCC2)cc1	InChI=1S/C17H20N6O2S/c1-19-26(24,25)15-7-5-14(6-8-15)21-17-20-12-13(11-18)16(22-17)23-9-3-2-4-10-23/h5-8,12,19H,2-4,9-10H2,1H3,(H,20,21,22)	YUOHLMLGTIBJMB-UHFFFAOYSA-N	676371	US20240166635, Example 91	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676371	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676371&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090289	500592104							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415885	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)-c2ccc(O)cc2)cc1	InChI=1S/C17H13N5O3S/c18-9-12-10-20-17(22-16(12)11-1-5-14(23)6-2-11)21-13-3-7-15(8-4-13)26(19,24)25/h1-8,10,23H,(H2,19,24,25)(H,20,21,22)	YQVYMELPOPTNDV-UHFFFAOYSA-N	676372	US20240166635, Example 92	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676372	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676372&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090135	500592105							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415890	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)-c2ccccc2)cc1	InChI=1S/C17H13N5O2S/c18-10-13-11-20-17(22-16(13)12-4-2-1-3-5-12)21-14-6-8-15(9-7-14)25(19,23)24/h1-9,11H,(H2,19,23,24)(H,20,21,22)	IGOROQLHPXKXMH-UHFFFAOYSA-N	676373	US20240166635, Example 93	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676373&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090295	500592106							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415896	Cc1cccc(c1)-c1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C#N	InChI=1S/C18H15N5O2S/c1-12-3-2-4-13(9-12)17-14(10-19)11-21-18(23-17)22-15-5-7-16(8-6-15)26(20,24)25/h2-9,11H,1H3,(H2,20,24,25)(H,21,22,23)	WWUCODWMCLZRMM-UHFFFAOYSA-N	676374	US20240166635, Example 94	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676374&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090290	500592107							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416409	CCc1cnc(Nc2ccc(cc2)S(=O)(=O)NC)nc1OC1COCCC1(C)O	InChI=1S/C19H26N4O5S/c1-4-13-11-21-18(22-14-5-7-15(8-6-14)29(25,26)20-3)23-17(13)28-16-12-27-10-9-19(16,2)24/h5-8,11,16,20,24H,4,9-10,12H2,1-3H3,(H,21,22,23)	KQLNBJJXDOONCE-UHFFFAOYSA-N	676484	US20240166635, Example 153a::US20240166635, Example 153b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676484&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990681	500592176							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416418	CC1(O)CCCC1Oc1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C1CC1	InChI=1S/C19H24N4O4S/c1-19(24)10-2-3-16(19)27-17-15(12-4-5-12)11-21-18(23-17)22-13-6-8-14(9-7-13)28(20,25)26/h6-9,11-12,16,24H,2-5,10H2,1H3,(H2,20,25,26)(H,21,22,23)	BYZQLJVRMDAADW-UHFFFAOYSA-N	676486	US20240166635, Example 154a::US20240166635, Example 154b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676486&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171581979	500592177							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416427	NS(=O)(=O)c1ccc(Nc2ncc(C=C)c(OC3CCCC3O)n2)cc1	InChI=1S/C17H20N4O4S/c1-2-11-10-19-17(21-16(11)25-15-5-3-4-14(15)22)20-12-6-8-13(9-7-12)26(18,23)24/h2,6-10,14-15,22H,1,3-5H2,(H2,18,23,24)(H,19,20,21)	BNFADTVYPPIEFB-UHFFFAOYSA-N	676488	US20240166635, Example 155a::US20240166635, Example 155b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676488&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090009	500592178							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415759	Cn1ccc(n1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(OCC2(C)CCCC2)n1	InChI=1S/C21H29N7O3S/c1-21(8-3-4-9-21)15-31-19-16(13-22)14-23-20(25-19)24-17-5-11-28(12-6-17)32(29,30)18-7-10-27(2)26-18/h7,10,14,17H,3-6,8-9,11-12,15H2,1-2H3,(H,23,24,25)	MVTRGLCCCNTBRI-UHFFFAOYSA-N	676342	US20240166635, Example 63	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676342&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089920	500592076							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415764	CO[C@H]1CC(C)(COc2nc(NC3CCN(CC3)S(=O)(=O)c3cnn(C)c3)ncc2C#N)C1	InChI=1S/C21H29N7O4S/c1-21(8-17(9-21)31-3)14-32-19-15(10-22)11-23-20(26-19)25-16-4-6-28(7-5-16)33(29,30)18-12-24-27(2)13-18/h11-13,16-17H,4-9,14H2,1-3H3,(H,23,25,26)/t17-,21?	PRSYHOVETSXLAW-KJPGQXGLSA-N	676343	US20240166635, Example 64a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676343&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089918	500592077							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415769	CO[C@H]1CC(C)(COc2nc(NC3CCN(CC3)S(=O)(=O)c3cnn(C)c3)ncc2C#N)C1	InChI=1S/C21H29N7O4S/c1-21(8-17(9-21)31-3)14-32-19-15(10-22)11-23-20(26-19)25-16-4-6-28(7-5-16)33(29,30)18-12-24-27(2)13-18/h11-13,16-17H,4-9,14H2,1-3H3,(H,23,25,26)/t17-,21?	PRSYHOVETSXLAW-KJPGQXGLSA-N	676344	US20240166635, Example 64b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676344&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089918	500592078							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415775	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)N2CCCCC2)cc1	InChI=1S/C16H18N6O2S/c17-10-12-11-19-16(21-15(12)22-8-2-1-3-9-22)20-13-4-6-14(7-5-13)25(18,23)24/h4-7,11H,1-3,8-9H2,(H2,18,23,24)(H,19,20,21)	NBOMRDUNYYSFKM-UHFFFAOYSA-N	676345	US20240166635, Example 65	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676345&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090089	500592079							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415780	O=S(=O)(NC1COC1)c1ccc(Nc2ncc(C#N)c(n2)N2CCCCC2)cc1	InChI=1S/C19H22N6O3S/c20-10-14-11-21-19(23-18(14)25-8-2-1-3-9-25)22-15-4-6-17(7-5-15)29(26,27)24-16-12-28-13-16/h4-7,11,16,24H,1-3,8-9,12-13H2,(H,21,22,23)	QNPDOIYFTPKZBE-UHFFFAOYSA-N	676346	US20240166635, Example 66	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676346&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090093	500592080							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415784	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)N2CCCC2)cc1	InChI=1S/C15H16N6O2S/c16-9-11-10-18-15(20-14(11)21-7-1-2-8-21)19-12-3-5-13(6-4-12)24(17,22)23/h3-6,10H,1-2,7-8H2,(H2,17,22,23)(H,18,19,20)	YKFDYHJLVVHLTA-UHFFFAOYSA-N	676347	US20240166635, Example 67	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676347&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090215	500592081							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415790	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)N2CCCCCC2)cc1	InChI=1S/C17H20N6O2S/c18-11-13-12-20-17(22-16(13)23-9-3-1-2-4-10-23)21-14-5-7-15(8-6-14)26(19,24)25/h5-8,12H,1-4,9-10H2,(H2,19,24,25)(H,20,21,22)	MUUHVLDSAITAAO-UHFFFAOYSA-N	676348	US20240166635, Example 68	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676348&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171581863	500592082							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415902	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)-c2cccc(F)c2)cc1	InChI=1S/C17H12FN5O2S/c18-13-3-1-2-11(8-13)16-12(9-19)10-21-17(23-16)22-14-4-6-15(7-5-14)26(20,24)25/h1-8,10H,(H2,20,24,25)(H,21,22,23)	YTFAWDKXLZSGSL-UHFFFAOYSA-N	676375	US20240166635, Example 95	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676375	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676375&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090292	500592108							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415907	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)-c2cccc(c2)C2CC2)cc1	InChI=1S/C20H17N5O2S/c21-11-16-12-23-20(24-17-6-8-18(9-7-17)28(22,26)27)25-19(16)15-3-1-2-14(10-15)13-4-5-13/h1-3,6-10,12-13H,4-5H2,(H2,22,26,27)(H,23,24,25)	CYCJLUNVGZAGRO-UHFFFAOYSA-N	676376	US20240166635, Example 96	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676376&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090293	500592109							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415913	CNc1cccc(c1)-c1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C#N	InChI=1S/C18H16N6O2S/c1-21-15-4-2-3-12(9-15)17-13(10-19)11-22-18(24-17)23-14-5-7-16(8-6-14)27(20,25)26/h2-9,11,21H,1H3,(H2,20,25,26)(H,22,23,24)	XQOFTUUMVMHGIW-UHFFFAOYSA-N	676377	US20240166635, Example 97	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676377&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090291	500592110							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415918	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)-c2cccc(O)c2)cc1	InChI=1S/C17H13N5O3S/c18-9-12-10-20-17(22-16(12)11-2-1-3-14(23)8-11)21-13-4-6-15(7-5-13)26(19,24)25/h1-8,10,23H,(H2,19,24,25)(H,20,21,22)	LRALYODTTDLYCD-UHFFFAOYSA-N	676378	US20240166635, Example 98	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676378&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090288	500592111							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415924	NS(=O)(=O)c1ccc(Nc2ncc(c(O[C@H]3CCC[C@H]3O)n2)C(F)(F)F)cc1	InChI=1S/C16H17F3N4O4S/c17-16(18,19)11-8-21-15(23-14(11)27-13-3-1-2-12(13)24)22-9-4-6-10(7-5-9)28(20,25)26/h4-8,12-13,24H,1-3H2,(H2,20,25,26)(H,21,22,23)/t12-,13+/m1/s1	ALDIKYMFXCVIAW-OLZOCXBDSA-N	676379	US20240166635, Example 99a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676379&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090063	500592112							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415933	CNS(=O)(=O)c1ccc(Nc2ncc(c(O[C@H]3CCOC[C@H]3O)n2)C(F)(F)F)cc1	InChI=1S/C17H19F3N4O5S/c1-21-30(26,27)11-4-2-10(3-5-11)23-16-22-8-12(17(18,19)20)15(24-16)29-14-6-7-28-9-13(14)25/h2-5,8,13-14,21,25H,6-7,9H2,1H3,(H,22,23,24)/t13-,14+/m1/s1	PCCSUZXFRYBZTH-KGLIPLIRSA-N	676381	US20240166635, Example 100a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676381&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090320	500592114							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415942	CNS(=O)(=O)c1ccc(Nc2ncc(c(O[C@H]3CCOC[C@H]3O)n2)C(F)(F)F)c(F)c1	InChI=1S/C17H18F4N4O5S/c1-22-31(27,28)9-2-3-12(11(18)6-9)24-16-23-7-10(17(19,20)21)15(25-16)30-14-4-5-29-8-13(14)26/h2-3,6-7,13-14,22,26H,4-5,8H2,1H3,(H,23,24,25)/t13-,14+/m1/s1	PNHFLLNBUUXGEW-KGLIPLIRSA-N	676383	US20240166635, Example 101a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676383&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990658	500592116							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415794	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)N2CCC[C@H](O)C2)cc1	InChI=1S/C16H18N6O3S/c17-8-11-9-19-16(21-15(11)22-7-1-2-13(23)10-22)20-12-3-5-14(6-4-12)26(18,24)25/h3-6,9,13,23H,1-2,7,10H2,(H2,18,24,25)(H,19,20,21)/t13-/m0/s1	DFJLEZDVQRKMPU-ZDUSSCGKSA-N	676349	US20240166635, Example 69	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676349&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090204	500592083							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415798	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)N2CCC[C@@H](O)C2)cc1	InChI=1S/C16H18N6O3S/c17-8-11-9-19-16(21-15(11)22-7-1-2-13(23)10-22)20-12-3-5-14(6-4-12)26(18,24)25/h3-6,9,13,23H,1-2,7,10H2,(H2,18,24,25)(H,19,20,21)/t13-/m1/s1	DFJLEZDVQRKMPU-CYBMUJFWSA-N	676350	US20240166635, Example 70	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676350&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090207	500592084							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415803	C[C@H]1CCCN(C1)c1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C#N	InChI=1S/C17H20N6O2S/c1-12-3-2-8-23(11-12)16-13(9-18)10-20-17(22-16)21-14-4-6-15(7-5-14)26(19,24)25/h4-7,10,12H,2-3,8,11H2,1H3,(H2,19,24,25)(H,20,21,22)/t12-/m0/s1	IGLHISZMQZPVOP-LBPRGKRZSA-N	676351	US20240166635, Example 71	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676351&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090198	500592085							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415808	C[C@@H]1CCCN(C1)c1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C#N	InChI=1S/C17H20N6O2S/c1-12-3-2-8-23(11-12)16-13(9-18)10-20-17(22-16)21-14-4-6-15(7-5-14)26(19,24)25/h4-7,10,12H,2-3,8,11H2,1H3,(H2,19,24,25)(H,20,21,22)/t12-/m1/s1	IGLHISZMQZPVOP-GFCCVEGCSA-N	676352	US20240166635, Example 72	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676352&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090199	500592086							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415813	C[C@@H]1CCCCN1c1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C#N	InChI=1S/C17H20N6O2S/c1-12-4-2-3-9-23(12)16-13(10-18)11-20-17(22-16)21-14-5-7-15(8-6-14)26(19,24)25/h5-8,11-12H,2-4,9H2,1H3,(H2,19,24,25)(H,20,21,22)/t12-/m1/s1	CPPKSKHDVMJSGS-GFCCVEGCSA-N	676353	US20240166635, Example 73	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676353&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090197	500592087							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415818	C[C@H]1CCCCN1c1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C#N	InChI=1S/C17H20N6O2S/c1-12-4-2-3-9-23(12)16-13(10-18)11-20-17(22-16)21-14-5-7-15(8-6-14)26(19,24)25/h5-8,11-12H,2-4,9H2,1H3,(H2,19,24,25)(H,20,21,22)/t12-/m0/s1	CPPKSKHDVMJSGS-LBPRGKRZSA-N	676354	US20240166635, Example 74	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676354&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090106	500592088							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415951	CNS(=O)(=O)c1ccc(Nc2ncc(c(O[C@H]3CCCOC[C@H]3O)n2)C(F)(F)F)cc1	InChI=1S/C18H21F3N4O5S/c1-22-31(27,28)12-6-4-11(5-7-12)24-17-23-9-13(18(19,20)21)16(25-17)30-15-3-2-8-29-10-14(15)26/h4-7,9,14-15,22,26H,2-3,8,10H2,1H3,(H,23,24,25)/t14-,15+/m1/s1	SVFDHGCURGAGIM-CABCVRRESA-N	676385	US20240166635, Example 102a::US20240166635, Example 103a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676385&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990660	500592118							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415956	CNS(=O)(=O)c1ccc(Nc2ncc(c(O[C@@H]3CCCOC[C@H]3O)n2)C(F)(F)F)cc1	InChI=1S/C18H21F3N4O5S/c1-22-31(27,28)12-6-4-11(5-7-12)24-17-23-9-13(18(19,20)21)16(25-17)30-15-3-2-8-29-10-14(15)26/h4-7,9,14-15,22,26H,2-3,8,10H2,1H3,(H,23,24,25)/t14-,15-/m1/s1	SVFDHGCURGAGIM-HUUCEWRRSA-N	676386	US20240166635, Example 102b::US20240166635, Example 103b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676386&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990661	500592119							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415961	CNS(=O)(=O)c1ccc(Nc2ncc(c(O[C@H]3CCCOC[C@@H]3O)n2)C(F)(F)F)cc1	InChI=1S/C18H21F3N4O5S/c1-22-31(27,28)12-6-4-11(5-7-12)24-17-23-9-13(18(19,20)21)16(25-17)30-15-3-2-8-29-10-14(15)26/h4-7,9,14-15,22,26H,2-3,8,10H2,1H3,(H,23,24,25)/t14-,15-/m0/s1	SVFDHGCURGAGIM-GJZGRUSLSA-N	676387	US20240166635, Example 102c	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676387&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990662	500592120							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415966	CNS(=O)(=O)c1ccc(Nc2ncc(c(O[C@@H]3CCCOC[C@@H]3O)n2)C(F)(F)F)cc1	InChI=1S/C18H21F3N4O5S/c1-22-31(27,28)12-6-4-11(5-7-12)24-17-23-9-13(18(19,20)21)16(25-17)30-15-3-2-8-29-10-14(15)26/h4-7,9,14-15,22,26H,2-3,8,10H2,1H3,(H,23,24,25)/t14-,15+/m0/s1	SVFDHGCURGAGIM-LSDHHAIUSA-N	676388	US20240166635, Example 102d	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676388&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990663	500592121							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415971	CNS(=O)(=O)c1ccc(Nc2ncc(c(O[C@H]3CCCOC[C@H]3O)n2)C(F)(F)F)cc1	InChI=1S/C18H21F3N4O5S/c1-22-31(27,28)12-6-4-11(5-7-12)24-17-23-9-13(18(19,20)21)16(25-17)30-15-3-2-8-29-10-14(15)26/h4-7,9,14-15,22,26H,2-3,8,10H2,1H3,(H,23,24,25)/t14-,15+/m1/s1	SVFDHGCURGAGIM-CABCVRRESA-N	676385	US20240166635, Example 102a::US20240166635, Example 103a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676385&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990660	500592118							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415977	CNS(=O)(=O)c1ccc(Nc2ncc(c(O[C@@H]3CCCOC[C@H]3O)n2)C(F)(F)F)cc1	InChI=1S/C18H21F3N4O5S/c1-22-31(27,28)12-6-4-11(5-7-12)24-17-23-9-13(18(19,20)21)16(25-17)30-15-3-2-8-29-10-14(15)26/h4-7,9,14-15,22,26H,2-3,8,10H2,1H3,(H,23,24,25)/t14-,15-/m1/s1	SVFDHGCURGAGIM-HUUCEWRRSA-N	676386	US20240166635, Example 102b::US20240166635, Example 103b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676386&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990661	500592119							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415982	C[C@@]1(O)COC[C@@H]1Oc1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C(F)(F)F	InChI=1S/C16H23F3N4O5S/c1-15(24)9-27-8-12(15)28-13-11(16(17,18)19)7-20-14(22-13)21-10-3-5-23(6-4-10)29(2,25)26/h7,10,12,24H,3-6,8-9H2,1-2H3,(H,20,21,22)/t12-,15+/m0/s1	MWILTCFDLRXJDY-SWLSCSKDSA-N	676391	US20240166635, Example 104a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676391&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090148	500592122							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415276	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OCC3CCCC3)n2)cc1	InChI=1S/C17H19N5O3S/c18-9-13-10-20-17(22-16(13)25-11-12-3-1-2-4-12)21-14-5-7-15(8-6-14)26(19,23)24/h5-8,10,12H,1-4,11H2,(H2,19,23,24)(H,20,21,22)	KDYMFYUQBRLCPF-UHFFFAOYSA-N	676208	US20240166635, Example 1	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676208&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090124	500591978							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415282	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(O[C@H]3CCCC[C@H]3O)n2)cc1	InChI=1S/C17H19N5O4S/c18-9-11-10-20-17(21-12-5-7-13(8-6-12)27(19,24)25)22-16(11)26-15-4-2-1-3-14(15)23/h5-8,10,14-15,23H,1-4H2,(H2,19,24,25)(H,20,21,22)/t14-,15+/m1/s1	FMDFEAPBRWULAI-CABCVRRESA-N	676209	US20240166635, Example 2a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676209	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676209&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090065	500591979							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415294	C[C@@]1(O)CCC[C@H]1Oc1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C#N	InChI=1S/C17H25N5O4S/c1-17(23)7-3-4-14(17)26-15-12(10-18)11-19-16(21-15)20-13-5-8-22(9-6-13)27(2,24)25/h11,13-14,23H,3-9H2,1-2H3,(H,19,20,21)/t14-,17-/m1/s1	IETNNOKBNYLBJP-RHSMWYFYSA-N	676212	US20240166635, Example 3b::US20240166635, Example 5b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676212	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676212&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990626	500591982							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415300	C[C@@]1(O)CC(F)(F)C[C@@H]1Oc1nc(NC2CCN(CC2)S(C)(=O)=O)ncc1C#N	InChI=1S/C17H23F2N5O4S/c1-16(25)10-17(18,19)7-13(16)28-14-11(8-20)9-21-15(23-14)22-12-3-5-24(6-4-12)29(2,26)27/h9,12-13,25H,3-7,10H2,1-2H3,(H,21,22,23)/t13-,16+/m0/s1	OUOWWDXNOOHBGP-XJKSGUPXSA-N	676213	US20240166635, Example 4a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676213	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676213&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090147	500591983							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415993	CNS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCCC3O)n2)C(F)(F)F)cc1	InChI=1S/C17H19F3N4O4S/c1-21-29(26,27)11-7-5-10(6-8-11)23-16-22-9-12(17(18,19)20)15(24-16)28-14-4-2-3-13(14)25/h5-9,13-14,21,25H,2-4H2,1H3,(H,22,23,24)	ARZCNFVGTWMROY-UHFFFAOYSA-N	676393	US20240166635, Example 105a::US20240166635, Example 105b::US20240166635, Example 109a::US20240166635, Example 109b::US20240166635, Example 110a::US20240166635, Example 110b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676393&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090112	500592124							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416002	CC(C)NS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCCC3O)n2)C(F)(F)F)cc1	InChI=1S/C19H23F3N4O4S/c1-11(2)26-31(28,29)13-8-6-12(7-9-13)24-18-23-10-14(19(20,21)22)17(25-18)30-16-5-3-4-15(16)27/h6-11,15-16,26-27H,3-5H2,1-2H3,(H,23,24,25)	YTRZTOPIENEURB-UHFFFAOYSA-N	676395	US20240166635, Example 106a::US20240166635, Example 106b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676395&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090110	500592125							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415321	C[C@@]1(O)CCC[C@@H]1Oc1nc(N[C@@H]2CCN(C[C@@H]2F)S(C)(=O)=O)ncc1C#N	InChI=1S/C17H24FN5O4S/c1-17(24)6-3-4-14(17)27-15-11(8-19)9-20-16(22-15)21-13-5-7-23(10-12(13)18)28(2,25)26/h9,12-14,24H,3-7,10H2,1-2H3,(H,20,21,22)/t12-,13+,14-,17+/m0/s1	XNTXGZBBRXIZGX-QDEZUTFSSA-N	676217	US20240166635, Example 6a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676217	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676217&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090128	500591985							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415336	Cn1cc(cn1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(O[C@H]2CCC(F)(F)C[C@@]2(C)O)n1	InChI=1S/C21H27F2N7O4S/c1-20(31)13-21(22,23)6-3-17(20)34-18-14(9-24)10-25-19(28-18)27-15-4-7-30(8-5-15)35(32,33)16-11-26-29(2)12-16/h10-12,15,17,31H,3-8,13H2,1-2H3,(H,25,27,28)/t17-,20+/m0/s1	AXRXMZKVXARJEN-FXAWDEMLSA-N	676233	US20240166635, Example 7a	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676233	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676233&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089991	500592001							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415341	Cn1cc(cn1)S(=O)(=O)N1CCC(CC1)Nc1ncc(C#N)c(O[C@@H]2CCC(F)(F)C[C@@]2(C)O)n1	InChI=1S/C21H27F2N7O4S/c1-20(31)13-21(22,23)6-3-17(20)34-18-14(9-24)10-25-19(28-18)27-15-4-7-30(8-5-15)35(32,33)16-11-26-29(2)12-16/h10-12,15,17,31H,3-8,13H2,1-2H3,(H,25,27,28)/t17-,20-/m1/s1	AXRXMZKVXARJEN-YLJYHZDGSA-N	676244	US20240166635, Example 7b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676244&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990647	500592012							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415346	CC1(COc2nc(NC3CCN(CC3)S(=O)(=O)c3cn[nH]c3)ncc2C#N)CCCC1	InChI=1S/C20H27N7O3S/c1-20(6-2-3-7-20)14-30-18-15(10-21)11-22-19(26-18)25-16-4-8-27(9-5-16)31(28,29)17-12-23-24-13-17/h11-13,16H,2-9,14H2,1H3,(H,23,24)(H,22,25,26)	LRSWKUYIXWJVFN-UHFFFAOYSA-N	676245	US20240166635, Example 8	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676245	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676245&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090004	500592013							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416011	OC1CCCC1Oc1nc(Nc2ccc(cc2)S(=O)(=O)NC2CC2)ncc1C(F)(F)F	InChI=1S/C19H21F3N4O4S/c20-19(21,22)14-10-23-18(25-17(14)30-16-3-1-2-15(16)27)24-11-6-8-13(9-7-11)31(28,29)26-12-4-5-12/h6-10,12,15-16,26-27H,1-5H2,(H,23,24,25)	PPASDCICDCXUJF-UHFFFAOYSA-N	676397	US20240166635, Example 107a::US20240166635, Example 107b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676397&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090352	500592126							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416020	CNS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCCC3)n2)C(F)(F)F)cc1	InChI=1S/C17H19F3N4O3S/c1-21-28(25,26)13-8-6-11(7-9-13)23-16-22-10-14(17(18,19)20)15(24-16)27-12-4-2-3-5-12/h6-10,12,21H,2-5H2,1H3,(H,22,23,24)	OURKCQIQALLKJV-UHFFFAOYSA-N	676399	US20240166635, Example 108	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676399&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990665	500592127							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416026	CNS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCCC3O)n2)C(F)(F)F)cc1	InChI=1S/C17H19F3N4O4S/c1-21-29(26,27)11-7-5-10(6-8-11)23-16-22-9-12(17(18,19)20)15(24-16)28-14-4-2-3-13(14)25/h5-9,13-14,21,25H,2-4H2,1H3,(H,22,23,24)	ARZCNFVGTWMROY-UHFFFAOYSA-N	676393	US20240166635, Example 105a::US20240166635, Example 105b::US20240166635, Example 109a::US20240166635, Example 109b::US20240166635, Example 110a::US20240166635, Example 110b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676393&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090112	500592124							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416035	CNS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCCC3O)n2)C(F)(F)F)cc1	InChI=1S/C17H19F3N4O4S/c1-21-29(26,27)11-7-5-10(6-8-11)23-16-22-9-12(17(18,19)20)15(24-16)28-14-4-2-3-13(14)25/h5-9,13-14,21,25H,2-4H2,1H3,(H,22,23,24)	ARZCNFVGTWMROY-UHFFFAOYSA-N	676393	US20240166635, Example 105a::US20240166635, Example 105b::US20240166635, Example 109a::US20240166635, Example 109b::US20240166635, Example 110a::US20240166635, Example 110b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676393&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090112	500592124							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416047	NS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCCCC3O)n2)C(F)(F)F)cc1	InChI=1S/C17H19F3N4O4S/c18-17(19,20)12-9-22-16(23-10-5-7-11(8-6-10)29(21,26)27)24-15(12)28-14-4-2-1-3-13(14)25/h5-9,13-14,25H,1-4H2,(H2,21,26,27)(H,22,23,24)	ZWWQVYKYWCWYFJ-UHFFFAOYSA-N	676404	US20240166635, Example 111a::US20240166635, Example 111b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676404&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090243	500592128							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416053	CC1CCCC(O)C1Oc1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C(F)(F)F	InChI=1S/C18H21F3N4O4S/c1-10-3-2-4-14(26)15(10)29-16-13(18(19,20)21)9-23-17(25-16)24-11-5-7-12(8-6-11)30(22,27)28/h5-10,14-15,26H,2-4H2,1H3,(H2,22,27,28)(H,23,24,25)	VGDVUMYVXOQBNE-UHFFFAOYSA-N	676406	US20240166635, Example 112a::US20240166635, Example 112b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676406&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090018	500592129							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415352	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OCC3CCC3)n2)cc1	InChI=1S/C16H17N5O3S/c17-8-12-9-19-16(21-15(12)24-10-11-2-1-3-11)20-13-4-6-14(7-5-13)25(18,22)23/h4-7,9,11H,1-3,10H2,(H2,18,22,23)(H,19,20,21)	TZUUUOFIEZNZEI-UHFFFAOYSA-N	676246	US20240166635, Example 9	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676246	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676246&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090216	500592014							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415358	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OC3CCCC3)n2)cc1	InChI=1S/C16H17N5O3S/c17-9-11-10-19-16(21-15(11)24-13-3-1-2-4-13)20-12-5-7-14(8-6-12)25(18,22)23/h5-8,10,13H,1-4H2,(H2,18,22,23)(H,19,20,21)	VEZGUWKKHGUXIU-UHFFFAOYSA-N	676248	US20240166635, Example 10	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676248	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676248&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090214	500592016							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415367	CC1(COc2nc(Nc3ccc(cc3)S(N)(=O)=O)ncc2C#N)CCCC1	InChI=1S/C18H21N5O3S/c1-18(8-2-3-9-18)12-26-16-13(10-19)11-21-17(23-16)22-14-4-6-15(7-5-14)27(20,24)25/h4-7,11H,2-3,8-9,12H2,1H3,(H2,20,24,25)(H,21,22,23)	ULVXDRPXXHOYNY-UHFFFAOYSA-N	676250	US20240166635, Example 12	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676250	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676250&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090211	500592018							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415374	CC1(COc2nc(Nc3ccc(cc3)S(N)(=O)=O)ncc2C#N)CCCCC1	InChI=1S/C19H23N5O3S/c1-19(9-3-2-4-10-19)13-27-17-14(11-20)12-22-18(24-17)23-15-5-7-16(8-6-15)28(21,25)26/h5-8,12H,2-4,9-10,13H2,1H3,(H2,21,25,26)(H,22,23,24)	KBMATRHLMSLNLI-UHFFFAOYSA-N	676252	US20240166635, Example 14	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676252&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090218	500592020							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415379	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OCC3(CO)CCCC3)n2)cc1	InChI=1S/C18H21N5O4S/c19-9-13-10-21-17(22-14-3-5-15(6-4-14)28(20,25)26)23-16(13)27-12-18(11-24)7-1-2-8-18/h3-6,10,24H,1-2,7-8,11-12H2,(H2,20,25,26)(H,21,22,23)	JDUIELGVEPIVMG-UHFFFAOYSA-N	676253	US20240166635, Example 15	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676253&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090221	500592021							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415386	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(OCC3(CO)CCCCC3)n2)cc1	InChI=1S/C19H23N5O4S/c20-10-14-11-22-18(23-15-4-6-16(7-5-15)29(21,26)27)24-17(14)28-13-19(12-25)8-2-1-3-9-19/h4-7,11,25H,1-3,8-9,12-13H2,(H2,21,26,27)(H,22,23,24)	VOYJSPOKUPFXBV-UHFFFAOYSA-N	676255	US20240166635, Example 17	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676255&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090212	500592023							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415841	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)N2CCC[C@H](F)C2)cc1	InChI=1S/C16H17FN6O2S/c17-12-2-1-7-23(10-12)15-11(8-18)9-20-16(22-15)21-13-3-5-14(6-4-13)26(19,24)25/h3-6,9,12H,1-2,7,10H2,(H2,19,24,25)(H,20,21,22)/t12-/m0/s1	NHURAJZSHKFCNL-LBPRGKRZSA-N	676361	US20240166635, Example 81	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676361	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676361&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090016	500592095							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415847	NS(=O)(=O)c1ccc(Nc2ncc(C#N)c(n2)N2CCC(O)CC2)cc1	InChI=1S/C16H18N6O3S/c17-9-11-10-19-16(21-15(11)22-7-5-13(23)6-8-22)20-12-1-3-14(4-2-12)26(18,24)25/h1-4,10,13,23H,5-8H2,(H2,18,24,25)(H,19,20,21)	YLLBIPKMNYSIAV-UHFFFAOYSA-N	676362	US20240166635, Example 82	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676362&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090014	500592096							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1415852	CC1(C)CCCN(C1)c1nc(Nc2ccc(cc2)S(N)(=O)=O)ncc1C#N	InChI=1S/C18H22N6O2S/c1-18(2)8-3-9-24(12-18)16-13(10-19)11-21-17(23-16)22-14-4-6-15(7-5-14)27(20,25)26/h4-7,11H,3,8-9,12H2,1-2H3,(H2,20,25,26)(H,21,22,23)	QBZZEVQQFQCIRK-UHFFFAOYSA-N	676363	US20240166635, Example 83	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		>1000							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676363	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676363&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090013	500592097							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416068	NS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCOCC3O)n2)C(F)(F)F)cc1	InChI=1S/C16H17F3N4O5S/c17-16(18,19)11-7-21-15(22-9-1-3-10(4-2-9)29(20,25)26)23-14(11)28-13-5-6-27-8-12(13)24/h1-4,7,12-13,24H,5-6,8H2,(H2,20,25,26)(H,21,22,23)	PYWQHGIYYMEYGG-UHFFFAOYSA-N	676410	US20240166635, Example 114a::US20240166635, Example 114b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676410&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167090335	500592131							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416075	NS(=O)(=O)c1ccc(Nc2ncc(c(OC3COCCC3O)n2)C(F)(F)F)cc1	InChI=1S/C16H17F3N4O5S/c17-16(18,19)11-7-21-15(22-9-1-3-10(4-2-9)29(20,25)26)23-14(11)28-13-8-27-6-5-12(13)24/h1-4,7,12-13,24H,5-6,8H2,(H2,20,25,26)(H,21,22,23)	WRWISRXAEHTYJK-UHFFFAOYSA-N	676412	US20240166635, Example 115a::US20240166635, Example 115b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 55							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676412&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089957	500592132							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416083	CNS(=O)(=O)c1ccc(Nc2ncc(c(OC3CCOCC3O)n2)C(F)(F)F)cc1	InChI=1S/C17H19F3N4O5S/c1-21-30(26,27)11-4-2-10(3-5-11)23-16-22-8-12(17(18,19)20)15(24-16)29-14-6-7-28-9-13(14)25/h2-5,8,13-14,21,25H,6-7,9H2,1H3,(H,22,23,24)	PCCSUZXFRYBZTH-UHFFFAOYSA-N	676414	US20240166635, Example 116a::US20240166635, Example 116b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676414&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			167089956	500592133							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7						
1416092	CNS(=O)(=O)c1ccc(Nc2ncc(c(OC3COCCC3O)n2)C(F)(F)F)cc1	InChI=1S/C17H19F3N4O5S/c1-21-30(26,27)11-4-2-10(3-5-11)23-16-22-8-12(17(18,19)20)15(24-16)29-14-9-28-7-6-13(14)25/h2-5,8,13-14,21,25H,6-7,9H2,1H3,(H,22,23,24)	VOMODKIWVHCAIR-UHFFFAOYSA-N	676416	US20240166635, Example 117a::US20240166635, Example 117b	CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7	Homo sapiens		 550							US Patent		10.7270/Q2GM8CMT			US20240166635	Cheng, D; Ding, Q; He, Z; Zhou, X; Zhou, Y; Yin, X; Xie, Z	Anrui Biomedical Technology (Guangzhou) Co.,Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=676416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=329&target=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=676416&enzyme=CDK-activating+kinase+assembly+factor+MAT1%2FCyclin-H%2FCyclin-dependent+kinase+7&column=ki&startPg=0&Increment=50&submit=Search			171990666	500592134							3	MYHNSSQKRHWTFSSEEQLARLRADANRKFRCKAVANGKVLPNDPVFLEPHEEMTLCKYYEKRLLEFCSVFKPAMPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDEFNVSSPQFVGNLRESPLGQEKALEQILEYELLLIQQLNFHLIVHNPYRPFEGFLIDLKTRYPILENPEILRKTADDFLNRIALTDAYLLYTPSQIALTAILSSASRAGITMESYLSESLMLKENRTCLSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDDDYVSKKSKHEEEEWTDDDLVESL	8PYR,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,8GXS,8GXQ,7B5Q,7B5O,6XD3,6XBZ,1KXU	Cyclin-H	CCNH_HUMAN	P51946	Q53X72 Q8TBL9							MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF	8P7L,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,1UA2,7B5Q,7B5O,6XBZ,8R9U,8R9S,8R9O,8R9A,8R99,8P4Z	Cyclin-dependent kinase 7	CDK7_HUMAN	P50613	Q9BS60 Q9UE19							MDDQGCPRCKTTKYRNPSLKLMVNVCGHTLCESCVDLLFVRGAGNCPECGTPLRKSNFRVQLFEDPTVDKEVEIRKKVLKIYNKREEDFPSLREYNDFLEEVEEIVFNLTNNVDLDNTKKKMEIYQKENKDVIQKNKLKLTREQEELEEALEVERQENEQRRLFIQKEEQLQQILKRKNKQAFLDELESSDLPVALLLAQHKDRSTQLEMQLEKPKPVKPVTFSTGIKMGQHISLAPIHKLEEALYEYQPLQIETYGPHVPELEMLGRLGYLNHVRAASPQDLAGGYTSSLACHRALQDAFSGLFWQPS	8P7L,7B5Q,7B5O,6XBZ,8GXS,8GXQ,6NMI,8PLZ,8P79,8P78,8P77,8P76,8P75,8P74,8P73,8P72,8P71,8P70,8P6Z,8P6Y,8P6X,8P6W,8P6V,8ORM,6XD3,8PYR,6TUN,1G25	CDK-activating kinase assembly factor MAT1	MAT1_HUMAN	P51948	G3V1U8 Q15817 Q6ICQ7