BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID PubChem SID ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 910548 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CC(C)O2)C2CCC2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C45H71NO12/c1-24-22-46(29-7-6-8-29)16-13-38(53-24)57-41-25(2)55-40(21-35(41)48)58-42-26(3)54-39(20-34(42)47)56-30-11-14-43(4)28(18-30)9-10-32-33(43)19-36(49)44(5)31(12-15-45(32,44)51)27-17-37(50)52-23-27/h17,24-26,28-36,38-42,47-49,51H,6-16,18-23H2,1-5H3/t24?,25-,26-,28?,30-,31+,32?,33?,34-,35-,36-,38?,39-,40-,41+,42+,43-,44-,45-/m0/s1 SBVAMPLOGURESG-GSUYKFLRSA-N 444840 US10668094, Compound DcB-(cyclic)::US10668094, Compound DtxcB-(cyclic)::US11077128, Compound DcB Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 4.00 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444840&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498557 440707077 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910552 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CC3CC3)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C45H71NO12/c1-24-21-46(22-27-6-7-27)15-12-38(53-24)57-41-25(2)55-40(20-35(41)48)58-42-26(3)54-39(19-34(42)47)56-30-10-13-43(4)29(17-30)8-9-32-33(43)18-36(49)44(5)31(11-14-45(32,44)51)28-16-37(50)52-23-28/h16,24-27,29-36,38-42,47-49,51H,6-15,17-23H2,1-5H3/t24?,25-,26-,29?,30-,31+,32?,33?,34-,35-,36-,38?,39-,40-,41+,42+,43-,44-,45-/m0/s1 ONAUXUUPVFWATH-LJYOIAAWSA-N 444975 US10668094, Compound DMcP-(cyclic)::US10668094, Compound DtxMcP-(cyclic) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 4.30 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444975&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498552 440707212 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910556 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CCS(C)(=O)=O)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C44H71NO14S/c1-24-22-45(15-16-60(6,51)52)14-11-37(54-24)58-40-25(2)56-39(21-34(40)47)59-41-26(3)55-38(20-33(41)46)57-29-9-12-42(4)28(18-29)7-8-31-32(42)19-35(48)43(5)30(10-13-44(31,43)50)27-17-36(49)53-23-27/h17,24-26,28-35,37-41,46-48,50H,7-16,18-23H2,1-6H3/t24?,25-,26-,28?,29-,30+,31?,32?,33-,34-,35-,37?,38-,39-,40+,41+,42-,43-,44-/m0/s1 RXELIABRBGFTHS-AJOSXQTQSA-N 444976 US10668094, Compound DESM-(sulfonyl) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 24.7 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444976&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498536 440707213 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910560 CCC(C)N1CCC(O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@@]5(C)C(CCC6C5C[C@H](O)[C@]5(C)[C@H](CC[C@]65O)C5=CC(=O)OC5)C4)O[C@H]3C)O[C@H]2C)OC(C)C1 InChI=1S/C45H73NO12/c1-8-24(2)46-16-13-38(53-25(3)22-46)57-41-26(4)55-40(21-35(41)48)58-42-27(5)54-39(20-34(42)47)56-30-11-14-43(6)29(18-30)9-10-32-33(43)19-36(49)44(7)31(12-15-45(32,44)51)28-17-37(50)52-23-28/h17,24-27,29-36,38-42,47-49,51H,8-16,18-23H2,1-7H3/t24?,25?,26-,27-,29?,30-,31+,32?,33?,34-,35-,36-,38?,39-,40-,41+,42+,43-,44-,45-/m0/s1 SIOAVHLOCSFVAJ-DLVJDMJTSA-N 444977 US10668094, Compound DiB Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 5.80 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444977&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 155802663 440707214 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910564 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CCS(N)(=O)=O)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C43H70N2O14S/c1-23-21-45(14-15-60(44,51)52)13-10-36(54-23)58-39-24(2)56-38(20-33(39)47)59-40-25(3)55-37(19-32(40)46)57-28-8-11-41(4)27(17-28)6-7-30-31(41)18-34(48)42(5)29(9-12-43(30,42)50)26-16-35(49)53-22-26/h16,23-25,27-34,36-40,46-48,50H,6-15,17-22H2,1-5H3,(H2,44,51,52)/t23?,24-,25-,27?,28-,29+,30?,31?,32-,33-,34-,36?,37-,38-,39+,40+,41-,42-,43-/m0/s1 ZEJHHDNVCMFAKT-ZVOBLZRGSA-N 444978 US10668094, Compound DESA-(sulfonamide) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 20.1 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444978&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498574 440707215 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910568 CC(C)N1CCC(O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@@]5(C)C(CCC6C5C[C@H](O)[C@]5(C)[C@H](CC[C@]65O)C5=CC(=O)OC5)C4)O[C@H]3C)O[C@H]2C)OC(C)C1 InChI=1S/C44H71NO12/c1-23(2)45-15-12-37(52-24(3)21-45)56-40-25(4)54-39(20-34(40)47)57-41-26(5)53-38(19-33(41)46)55-29-10-13-42(6)28(17-29)8-9-31-32(42)18-35(48)43(7)30(11-14-44(31,43)50)27-16-36(49)51-22-27/h16,23-26,28-35,37-41,46-48,50H,8-15,17-22H2,1-7H3/t24?,25-,26-,28?,29-,30+,31?,32?,33-,34-,35-,37?,38-,39-,40+,41+,42-,43-,44-/m0/s1 ZZSCZRRDHAFLAV-AJOSXQTQSA-N 444979 US10668094, Compound DiP Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 10.3 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444979&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 155802664 440707216 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910572 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CC(C)O2)C2CC2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C44H69NO12/c1-23-21-45(28-7-8-28)15-12-37(52-23)56-40-24(2)54-39(20-34(40)47)57-41-25(3)53-38(19-33(41)46)55-29-10-13-42(4)27(17-29)6-9-31-32(42)18-35(48)43(5)30(11-14-44(31,43)50)26-16-36(49)51-22-26/h16,23-25,27-35,37-41,46-48,50H,6-15,17-22H2,1-5H3/t23?,24-,25-,27?,29-,30+,31?,32?,33-,34-,35-,37?,38-,39-,40+,41+,42-,43-,44-/m0/s1 LJUOSQZLMDHEKF-DEGSDRIYSA-N 444980 US10668094, Compound DcP-(cyclic) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 8.10 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444980&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498539 440707217 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910576 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CCC3CC3)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C46H73NO12/c1-25-23-47(16-12-28-6-7-28)17-13-39(54-25)58-42-26(2)56-41(22-36(42)49)59-43-27(3)55-40(21-35(43)48)57-31-10-14-44(4)30(19-31)8-9-33-34(44)20-37(50)45(5)32(11-15-46(33,45)52)29-18-38(51)53-24-29/h18,25-28,30-37,39-43,48-50,52H,6-17,19-24H2,1-5H3/t25?,26-,27-,30?,31-,32+,33?,34?,35-,36-,37-,39?,40-,41-,42+,43+,44-,45-,46-/m0/s1 FTADYJGUJPYFPN-BDMCSPPPSA-N 444981 US10668094, Compound DEcP-(cyclic) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 7.20 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444981&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498556 440707218 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910580 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CS(C)(=O)=O)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C43H69NO14S/c1-23-20-44(22-59(6,50)51)14-11-36(53-23)57-39-24(2)55-38(19-33(39)46)58-40-25(3)54-37(18-32(40)45)56-28-9-12-41(4)27(16-28)7-8-30-31(41)17-34(47)42(5)29(10-13-43(30,42)49)26-15-35(48)52-21-26/h15,23-25,27-34,36-40,45-47,49H,7-14,16-22H2,1-6H3/t23?,24-,25-,27?,28-,29+,30?,31?,32-,33-,34-,36?,37-,38-,39+,40+,41-,42-,43-/m0/s1 BWIFYTYSHZTELV-ZVOBLZRGSA-N 444982 US10668094, Compound DMSM-(sulfonyl) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 89.0 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444982&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 140889046 440707219 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910584 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(Cc3ccccc3)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C48H71NO12/c1-27-24-49(25-30-9-7-6-8-10-30)18-15-41(56-27)60-44-28(2)58-43(23-38(44)51)61-45-29(3)57-42(22-37(45)50)59-33-13-16-46(4)32(20-33)11-12-35-36(46)21-39(52)47(5)34(14-17-48(35,47)54)31-19-40(53)55-26-31/h6-10,19,27-29,32-39,41-45,50-52,54H,11-18,20-26H2,1-5H3/t27?,28-,29-,32?,33-,34+,35?,36?,37-,38-,39-,41?,42-,43-,44+,45+,46-,47-,48-/m0/s1 BVEFYVNGHVRRTO-RGNCFJACSA-N 444983 US10668094, Compound DBz-(cyclic) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 5.60 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444983&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498561 440707220 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910588 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CC(C)O2)C2CCCCC2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C47H75NO12/c1-26-24-48(31-9-7-6-8-10-31)18-15-40(55-26)59-43-27(2)57-42(23-37(43)50)60-44-28(3)56-41(22-36(44)49)58-32-13-16-45(4)30(20-32)11-12-34-35(45)21-38(51)46(5)33(14-17-47(34,46)53)29-19-39(52)54-25-29/h19,26-28,30-38,40-44,49-51,53H,6-18,20-25H2,1-5H3/t26?,27-,28-,30?,32-,33+,34?,35?,36-,37-,38-,40?,41-,42-,43+,44+,45-,46-,47-/m0/s1 SALCYFHXTUYGSY-NWADUEKMSA-N 444984 US10668094, Compound DcH-(cyclic) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 11.7 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444984&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498560 440707221 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910592 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CC(F)(F)F)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C43H66F3NO12/c1-22-19-47(21-43(44,45)46)13-10-35(54-22)58-38-23(2)56-37(18-32(38)49)59-39-24(3)55-36(17-31(39)48)57-27-8-11-40(4)26(15-27)6-7-29-30(40)16-33(50)41(5)28(9-12-42(29,41)52)25-14-34(51)53-20-25/h14,22-24,26-33,35-39,48-50,52H,6-13,15-21H2,1-5H3/t22?,23-,24-,26?,27-,28+,29?,30?,31-,32-,33-,35?,36-,37-,38+,39+,40-,41-,42-/m0/s1 UNYFXQCNOFHMAF-NVAUYEMTSA-N 231662 DMeCF3 (13)::US10668094, Compound DCF3 Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 12.4 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=231662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=231662&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 127054042 336950909 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910596 CCN1CCC(O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@@]5(C)C(CCC6C5C[C@H](O)[C@]5(C)[C@H](CC[C@]65O)C5=CC(=O)OC5)C4)O[C@H]3C)O[C@H]2C)OC(C)C1 InChI=1S/C43H69NO12/c1-7-44-15-12-36(51-23(2)21-44)55-39-24(3)53-38(20-33(39)46)56-40-25(4)52-37(19-32(40)45)54-28-10-13-41(5)27(17-28)8-9-30-31(41)18-34(47)42(6)29(11-14-43(30,42)49)26-16-35(48)50-22-26/h16,23-25,27-34,36-40,45-47,49H,7-15,17-22H2,1-6H3/t23?,24-,25-,27?,28-,29+,30?,31?,32-,33-,34-,36?,37-,38-,39+,40+,41-,42-,43-/m0/s1 LCGZRYIGXYRVKQ-ZVOBLZRGSA-N 231661 DEt (12)::US10668094, Compound DEt Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 14.4 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=231661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=231661&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 127054041 336950908 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910600 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(C)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C42H67NO12/c1-22-20-43(6)14-11-35(50-22)54-38-23(2)52-37(19-32(38)45)55-39-24(3)51-36(18-31(39)44)53-27-9-12-40(4)26(16-27)7-8-29-30(40)17-33(46)41(5)28(10-13-42(29,41)48)25-15-34(47)49-21-25/h15,22-24,26-33,35-39,44-46,48H,7-14,16-21H2,1-6H3/t22?,23-,24-,26?,27-,28+,29?,30?,31-,32-,33-,35?,36-,37-,38+,39+,40-,41-,42-/m0/s1 IJOBTPPMUDSRAS-NVAUYEMTSA-N 231660 DMe (11)::US10668094, Compound DMe Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 10.8 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=231660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=231660&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 127054040 336950907 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910604 CCCN1CCC(O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@@]5(C)C(CCC6C5C[C@H](O)[C@]5(C)[C@H](CC[C@]65O)C5=CC(=O)OC5)C4)O[C@H]3C)O[C@H]2C)OC(C)C1 InChI=1S/C44H71NO12/c1-7-15-45-16-12-37(52-24(2)22-45)56-40-25(3)54-39(21-34(40)47)57-41-26(4)53-38(20-33(41)46)55-29-10-13-42(5)28(18-29)8-9-31-32(42)19-35(48)43(6)30(11-14-44(31,43)50)27-17-36(49)51-23-27/h17,24-26,28-35,37-41,46-48,50H,7-16,18-23H2,1-6H3/t24?,25-,26-,28?,29-,30+,31?,32?,33-,34-,35-,37?,38-,39-,40+,41+,42-,43-,44-/m0/s1 NJOZSUQORBIBBP-AJOSXQTQSA-N 444989 US10668094, Compound DP Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 9.80 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444989&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 155802666 440707226 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910608 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CC(C)O2)C(C)(C)C)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C45H73NO12/c1-24-22-46(42(4,5)6)16-13-37(53-24)57-40-25(2)55-39(21-34(40)48)58-41-26(3)54-38(20-33(41)47)56-29-11-14-43(7)28(18-29)9-10-31-32(43)19-35(49)44(8)30(12-15-45(31,44)51)27-17-36(50)52-23-27/h17,24-26,28-35,37-41,47-49,51H,9-16,18-23H2,1-8H3/t24?,25-,26-,28?,29-,30+,31?,32?,33-,34-,35-,37?,38-,39-,40+,41+,43-,44-,45-/m0/s1 BHLQJIKCXBAVDX-KQIAMWRXSA-N 444990 US10668094, Compound DtB Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 16.3 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444990&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 155802667 440707227 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910612 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CC3CC(C)(C)C3)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C48H77NO12/c1-26-23-49(24-29-21-45(4,5)22-29)15-12-40(56-26)60-43-27(2)58-42(20-37(43)51)61-44-28(3)57-41(19-36(44)50)59-32-10-13-46(6)31(17-32)8-9-34-35(46)18-38(52)47(7)33(11-14-48(34,47)54)30-16-39(53)55-25-30/h16,26-29,31-38,40-44,50-52,54H,8-15,17-25H2,1-7H3/t26?,27-,28-,31?,32-,33+,34?,35?,36-,37-,38-,40?,41-,42-,43+,44+,46-,47-,48-/m0/s1 GCAMATFHDAABBK-MAJPROTCSA-N 444991 US10668094, Compound DMDMcB-(cyclic) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 3.90 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444991&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498532 440707228 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910616 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CC(C)O2)C2CCC2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C45H71NO12/c1-24-22-46(29-7-6-8-29)16-13-38(53-24)57-41-25(2)55-40(21-35(41)48)58-42-26(3)54-39(20-34(42)47)56-30-11-14-43(4)28(18-30)9-10-32-33(43)19-36(49)44(5)31(12-15-45(32,44)51)27-17-37(50)52-23-27/h17,24-26,28-36,38-42,47-49,51H,6-16,18-23H2,1-5H3/t24?,25-,26-,28?,30-,31+,32?,33?,34-,35-,36-,38?,39-,40-,41+,42+,43-,44-,45-/m0/s1 SBVAMPLOGURESG-GSUYKFLRSA-N 444840 US10668094, Compound DcB-(cyclic)::US10668094, Compound DtxcB-(cyclic)::US11077128, Compound DcB Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 4.30 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444840&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498557 440707077 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910620 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CC3CC3)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C45H71NO12/c1-24-21-46(22-27-6-7-27)15-12-38(53-24)57-41-25(2)55-40(20-35(41)48)58-42-26(3)54-39(19-34(42)47)56-30-10-13-43(4)29(17-30)8-9-32-33(43)18-36(49)44(5)31(11-14-45(32,44)51)28-16-37(50)52-23-28/h16,24-27,29-36,38-42,47-49,51H,6-15,17-23H2,1-5H3/t24?,25-,26-,29?,30-,31+,32?,33?,34-,35-,36-,38?,39-,40-,41+,42+,43-,44-,45-/m0/s1 ONAUXUUPVFWATH-LJYOIAAWSA-N 444975 US10668094, Compound DMcP-(cyclic)::US10668094, Compound DtxMcP-(cyclic) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 3.70 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444975&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498552 440707212 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910624 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(C[Si](C)(C)C)CC(C)O2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C45H75NO12Si/c1-25-22-46(24-59(6,7)8)16-13-38(53-25)57-41-26(2)55-40(21-35(41)48)58-42-27(3)54-39(20-34(42)47)56-30-11-14-43(4)29(18-30)9-10-32-33(43)19-36(49)44(5)31(12-15-45(32,44)51)28-17-37(50)52-23-28/h17,25-27,29-36,38-42,47-49,51H,9-16,18-24H2,1-8H3/t25?,26-,27-,29?,30-,31+,32?,33?,34-,35-,36-,38?,39-,40-,41+,42+,43-,44-,45-/m0/s1 STBLRDWXSCHDBD-ONVXOOOQSA-N 444994 US10668094, Compound DTMS-(silyl) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 11.1 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444994&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 155802668 440707229 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910628 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4C[C@@H](O)[C@]4(C)[C@H](CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C InChI=1S/C41H64O14/c1-19-36(47)28(42)15-34(50-19)54-38-21(3)52-35(17-30(38)44)55-37-20(2)51-33(16-29(37)43)53-24-8-10-39(4)23(13-24)6-7-26-27(39)14-31(45)40(5)25(9-11-41(26,40)48)22-12-32(46)49-18-22/h12,19-21,23-31,33-38,42-45,47-48H,6-11,13-18H2,1-5H3/t19-,20-,21-,23-,24+,25-,26-,27+,28+,29+,30+,31-,33+,34+,35+,36-,37-,38-,39+,40+,41+/m1/s1 LTMHDMANZUZIPE-PUGKRICDSA-N 46355 DIGOXIN::MLS000069819::SMR000059217::US10668094, Compound Digoxin::cid_2724385 Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 42.8 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=46355 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=46355&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search DGX 3B0W,1IGJ,7DDH,4RET 2724385 252626917 4551 DB00390 4726 C06956 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910632 C[C@@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](OC2CCN(CC(C)O2)C2CCCC2)[C@H](C)O1)O[C@H]1CC[C@@]2(C)C(CCC3C2C[C@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1 InChI=1S/C46H73NO12/c1-25-23-47(30-8-6-7-9-30)17-14-39(54-25)58-42-26(2)56-41(22-36(42)49)59-43-27(3)55-40(21-35(43)48)57-31-12-15-44(4)29(19-31)10-11-33-34(44)20-37(50)45(5)32(13-16-46(33,45)52)28-18-38(51)53-24-28/h18,25-27,29-37,39-43,48-50,52H,6-17,19-24H2,1-5H3/t25?,26-,27-,29?,31-,32+,33?,34?,35-,36-,37-,39?,40-,41-,42+,43+,44-,45-,46-/m0/s1 GUEJIEJTPBVIPA-MFKBYWFQSA-N 444996 US10668094, Compound DcPe-(cyclic) Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 27.6 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444996&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search 126498578 440707231 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25 910636 C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]1[C@@H](O)C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3CC[C@@]4(C)[C@H](CC[C@@H]5[C@@H]4CC[C@]4(C)[C@H](CC[C@]54O)C4=CC(=O)OC4)C3)O[C@@H]2C)O[C@@H]1C InChI=1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1 WDJUZGPOPHTGOT-XUDUSOBPSA-N 46356 DIGITOXIN::MLS000069787::SMR000058529::US10668094, Compound Digitoxin::cid_441207 Sodium/potassium-transporting ATPase subunit alpha-2/beta-3 28.8 US Patent 10.7270/Q2FX7DH9 aid1804440 US10668094 Karlish, SJ; Katz, A; Tal, DM; Marcovich, A Yeda Research and Development Co. Ltd. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=46356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=com&complexid=313&target=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=46356&enzyme=Sodium%2Fpotassium-transporting+ATPase+subunit+alpha-2%2Fbeta-3&column=ki&startPg=0&Increment=50&submit=Search F9R 7DDI 441207 252626918 28544 DB01396 6782 C06955 ZINC95862733 2 MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA Sodium/potassium-transporting ATPase subunit beta-3 AT1B3_HUMAN P54709 B7Z1N7 MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 2ZXE,3A3Y,5AVQ,5AVR,5AVS,5AVT,5AVU,5AVV,5AVW,5AVX,5AVY,5AVZ,5AW0,5AW1,5AW2,5AW3,5AW4,5AW5,5AW6,5AW7,5AW8,5AW9,7WYU,7WYV,7WYW,7WYX,7WYY,7WYZ,7WZ0,7Y45,7Y46,7YZR,7Z04,8JFZ Sodium/potassium-transporting ATPase subunit alpha-2 AT1A2_HUMAN P50993 D3DVE4 Q07059 Q5JW74 Q86UZ5 Q9UQ25