Compile Data Set for Download or QSAR
Report error Found 1074 Enz. Inhib. hit(s) with Target = 'Potassium voltage-gated channel subfamily A member 3'
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50185446BDBM50185446(cardamonin | cardamomin | (E)-1-(2,4-dihydroxy-6-m...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human voltage-gated potassium channel Kv1.3 expressed in L929 cells by whole-cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279106BDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Kv1.3 expressed in mouse L929 cells exposed to depolarizing step pulses from -80 mV to +40 mV by whole cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279106BDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Kv1.3 potassium channel expressed in mouse L929 cells by whole cell patch clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279106BDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Kv1.3 (unknown origin) expressed in mouse L929 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279106BDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Kv1.3 in human T-lymphocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331458BDBM50331458(4-(4-phenylbutoxy)-7H-furo[3,2-g]chromen-7-one | 5...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Kv1.3 (unknown origin) expressed in mouse L929 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331458BDBM50331458(4-(4-phenylbutoxy)-7H-furo[3,2-g]chromen-7-one | 5...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Kv1.3 in human T-lymphocyte by whole cell patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125504BDBM50125504(Methyl-carbamic acid 4-[(2-methoxy-benzoylamino)-m...)
Affinity DataIC50: 5nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125521BDBM50125521(Propyl-carbamic acid 4-[(2-methoxy-benzoylamino)-m...)
Affinity DataIC50: 5nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 791991BDBM791991((S)-4-(2,3-Dichloro-6-hydroxyphenyl)-1-(1- methyl-...)
Affinity DataIC50: 5nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 792029BDBM792029((S)-4-(2,3-Dichloro-6-hydroxyphenyl)-1- (((1r,3r)-...)
Affinity DataIC50: 5nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 792030BDBM792030((S)-4-(2,3-Dichloro-6-hydroxyphenyl)-1-(4- hydroxy...)
Affinity DataIC50: 5nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 791990BDBM791990((S)-4-(2,3-Dichloro-6-hydroxyphenyl)-1-(3- hydroxy...)
Affinity DataIC50: 7.5nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 792028BDBM792028((S)-4-(2,3-Dichloro-6-hydroxyphenyl)-1- ((1r,3r)-3...)
Affinity DataIC50: 7.5nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 792032BDBM792032((S)-4-(2,3-Dichloro-6-hydroxyphenyl)-1-(5,6- dihyd...)
Affinity DataIC50: 7.5nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158202BDBM50158202(Correloid derivative | CHEMBL434526)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against voltage-gated potassium channel subunit Kv1.3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279106BDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of cloned Kv1.3 channel expressed in mammalian cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158200BDBM50158200(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 11nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158214BDBM50158214(Aceticacid(R)-1-[(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 12nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158213BDBM50158213(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 12nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158218BDBM50158218(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 12.3nMAssay Description:Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158224BDBM50158224(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 14nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158233BDBM50158233(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 14nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158233BDBM50158233(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 14.7nMAssay Description:Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158228BDBM50158228(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 17nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50293351BDBM50293351(4-(4-Phenoxybutoxy)-7H-furo[3,2-g]chromene-7-thion...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Kv1.3 potassium channel expressed in mouse L929 cells by whole cell patch clampMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50125498BDBM50125498(Allyl-carbamic acid 4-[(2-methoxy-benzoylamino)-me...)
Affinity DataIC50: 18nMAssay Description:Inhibition of DiTc binding to Kv1.3 channel in human brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158195BDBM50158195(Aceticacid(R)-1-[(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 19nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158227BDBM50158227(Aceticacid1-[4,5,6-triacetoxy-1-hydroxy-2,4a,11b-t...)
Affinity DataIC50: 19nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158210BDBM50158210(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 19nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 791960BDBM791960(US20260042734, Compound W1)
Affinity DataIC50: 20nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 791983BDBM791983(US20260042734, Compound W2)
Affinity DataIC50: 20nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 792027BDBM792027((S)-4-(2,3-Dichloro-6-hydroxyphenyl)-1-(2,2- diflu...)
Affinity DataIC50: 20nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 701610BDBM701610(US12128028, Example 6)
Affinity DataIC50: 20nMAssay Description:The QPatch HT system (Sophion Bioscience A/S, Denmark) was used with the conventional whole-cell configuration. This system is an automated, chip-bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158209BDBM50158209(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 21nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158226BDBM50158226(Aceticacid(R)-1-[(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 21nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50279106BDBM50279106(5-(4-phenoxybutoxy)psoralen | 4-(4-phenoxybutoxy)-...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human Kv1.3 expressed in CHO cells at -80 mV holding potential by whole cell automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158197BDBM50158197(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 24nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158217BDBM50158217(Aceticacid1-{(R)-4,5,6-triacetoxy-1-[2-(2-ethyl-ph...)
Affinity DataIC50: 25.5nMAssay Description:Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158210BDBM50158210(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 25.6nMAssay Description:Inhibitory activity against voltage-gated potassium channel subunit Kv1.3 of human T cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158215BDBM50158215(Aceticacid(R)-1-((4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 26nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158211BDBM50158211(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 26nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 701611BDBM701611(US12128028, Example 7)
Affinity DataIC50: 26nMAssay Description:The QPatch HT system (Sophion Bioscience A/S, Denmark) was used with the conventional whole-cell configuration. This system is an automated, chip-bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50650879BDBM50650879(CHEMBL5631442)
Affinity DataIC50: 26nMAssay Description:Inhibition of Kv1.3 (unknown origin) expressed in PBMC derived PHA-activated T-lymphocyte cells incubated for 5 days by manual patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 701612BDBM701612(US12128028, Example 8)
Affinity DataIC50: 27nMAssay Description:The QPatch HT system (Sophion Bioscience A/S, Denmark) was used with the conventional whole-cell configuration. This system is an automated, chip-bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158206BDBM50158206(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 28nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 701614BDBM701614(US12128028, Example 10)
Affinity DataIC50: 28nMAssay Description:The QPatch HT system (Sophion Bioscience A/S, Denmark) was used with the conventional whole-cell configuration. This system is an automated, chip-bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 701615BDBM701615(US12128028, Example 11)
Affinity DataIC50: 28nMAssay Description:The QPatch HT system (Sophion Bioscience A/S, Denmark) was used with the conventional whole-cell configuration. This system is an automated, chip-bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158216BDBM50158216(Aceticacid(R)-1-{(4R,4aR,5S,6R,6aR,11bS)-4,5,6-tri...)
Affinity DataIC50: 28nMAssay Description:Inhibition of voltage-gated potassium channel subunit Kv1.3 in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily A member 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 701613BDBM701613(US12128028, Example 9)
Affinity DataIC50: 28nMAssay Description:The QPatch HT system (Sophion Bioscience A/S, Denmark) was used with the conventional whole-cell configuration. This system is an automated, chip-bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
US Patent

Displayed 1 to 50 (of 1074 total ) | Next | Last >>
Jump to: