Compile Data Set for Download or QSAR
Report error Found 195 Enz. Inhib. hit(s) with Target = 'Phospholipid hydroperoxide glutathione peroxidase'
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547192BDBM50547192(CHEMBL4747331)
Affinity DataEC50:  12nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658842BDBM50658842(CHEMBL6169767)
Affinity DataKd:  20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622721BDBM50622721(CHEMBL5406796)
Affinity DataEC50:  23nMAssay Description:Induction of GPX4 degradation in human HT-1080 cells measured for 6 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658843BDBM50658843(CHEMBL4870989)
Affinity DataKd:  25nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622721BDBM50622721(CHEMBL5406796)
Affinity DataEC50:  26nMAssay Description:Induction of GPX4 degradation in human Gefitinib-resistant H1650 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 66431BDBM66431(2-(3-chloro-N-(2-chloroacetyl)-4-methoxyanilino)-N...)
Affinity DataEC50:  28nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649234BDBM50649234(CHEMBL5618406)
Affinity DataKd:  36nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622721BDBM50622721(CHEMBL5406796)
Affinity DataEC50:  43nMAssay Description:Induction of GPX4 degradation in human NCI-H1650 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547192BDBM50547192(CHEMBL4747331)
Affinity DataKd:  44nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547193BDBM50547193(CHEMBL1951048)
Affinity DataEC50:  44nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649254BDBM50649254(CHEMBL5619371)
Affinity DataKd:  48nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649235BDBM50649235(CHEMBL5619271)
Affinity DataKd:  48nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649252BDBM50649252(CHEMBL5618916)
Affinity DataKd:  114nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624231BDBM50624231(CHEMBL5422297)
Affinity DataIC50: 120nMAssay Description:Inhibition of GPX4 (unknown origin) incubated for 1 hrs in presence of glutathione and glutathione reductase by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624232BDBM50624232(CHEMBL5415644)
Affinity DataIC50: 130nMAssay Description:Inhibition of GPX4 (unknown origin) incubated for 1 hrs in presence of glutathione and glutathione reductase by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622721BDBM50622721(CHEMBL5406796)
Affinity DataEC50:  136nMAssay Description:Induction of GPX4 degradation in human Calu-1 cells measured for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547201BDBM50547201(CHEMBL4792343)
Affinity DataEC50:  150nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649253BDBM50649253(CHEMBL5620092)
Affinity DataKd:  160nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649273BDBM50649273(CHEMBL5619589)
Affinity DataKd:  170nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547204BDBM50547204(CHEMBL4760983)
Affinity DataEC50:  210nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649248BDBM50649248(CHEMBL5618596)
Affinity DataKd:  253nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649282BDBM50649282(CHEMBL5618364)
Affinity DataKd:  315nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547226BDBM50547226(CHEMBL1578061)
Affinity DataEC50:  340nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547205BDBM50547205(CHEMBL4780750)
Affinity DataEC50:  370nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649255BDBM50649255(CHEMBL5619014)
Affinity DataKd:  384nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547208BDBM50547208(CHEMBL4757878)
Affinity DataEC50:  420nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649249BDBM50649249(CHEMBL5619466)
Affinity DataKd:  426nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640748BDBM50640748(CHEMBL5570241)
Affinity DataIC50: 543nMAssay Description:Inhibition of GPX4 (unknown origin) incubated for 1 hr followed by NADPH and cumene hydroperoxide additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624232BDBM50624232(CHEMBL5415644)
Affinity DataKi:  590nMAssay Description:Covalent inhibition of GPX4 (unknown origin) assessed as inhibition constant incubated for 30 to 90 mins in presence of glutathione, glutathione redu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547194BDBM50547194(CHEMBL4748785)
Affinity DataEC50:  600nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624231BDBM50624231(CHEMBL5422297)
Affinity DataKi:  630nMAssay Description:Covalent inhibition of GPX4 (unknown origin) assessed as inhibition constant incubated for 30 to 90 mins in presence of glutathione, glutathione redu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547193BDBM50547193(CHEMBL1951048)
Affinity DataEC50:  650nMAssay Description:Induction of GPX4 degradation in human HT-1080 cells measured after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649300BDBM50649300(CHEMBL5618088)
Affinity DataKd:  717nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649284BDBM50649284(CHEMBL5618889)
Affinity DataKd:  784nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649257BDBM50649257(CHEMBL5619657)
Affinity DataKd:  809nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649250BDBM50649250(CHEMBL5619112)
Affinity DataKd:  835nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649276BDBM50649276(CHEMBL5618453)
Affinity DataKd:  931nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547206BDBM50547206(CHEMBL4751224)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649295BDBM50649295(CHEMBL5618933)
Affinity DataKd:  1.05E+3nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649296BDBM50649296(CHEMBL5618737)
Affinity DataKd:  1.14E+3nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547227BDBM50547227(CHEMBL4800659)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547209BDBM50547209(CHEMBL4779501)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649251BDBM50649251(CHEMBL5618450)
Affinity DataKd:  1.23E+3nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649274BDBM50649274(CHEMBL5619904)
Affinity DataKd:  1.27E+3nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547227BDBM50547227(CHEMBL4800659)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viability in presence of ferrostatin-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649285BDBM50649285(CHEMBL5619835)
Affinity DataKd:  1.51E+3nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649302BDBM50649302(CHEMBL5618907)
Affinity DataKd:  1.56E+3nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 64146BDBM64146(MLS001172197 | SMR000594705 | N-(1,3-benzodioxol-5...)
Affinity DataEC50:  1.60E+3nMAssay Description:Inhibition of GPX4 in human LOX IMVI cells assessed as ferroptosis-mediated cell death measured as cell viabilityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649304BDBM50649304(CHEMBL5619282)
Affinity DataKd:  1.72E+3nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPhospholipid hydroperoxide glutathione peroxidase(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50649266BDBM50649266(CHEMBL5620080)
Affinity DataKd:  1.79E+3nMAssay Description:Binding affinity to GPX4 (unknown origin) assessed as dissociation constant by surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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