Compile Data Set for Download or QSAR
Report error Found 1550 Enz. Inhib. hit(s) with Target = 'Nuclear factor erythroid 2-related factor 2'
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006932BDBM50006932(CHEMBL3237245)
Affinity DataKi:  1nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) assessed as inhibition constant by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657739BDBM50657739(CHEMBL6149020)
Affinity DataEC50:  1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657741BDBM50657741(CHEMBL6162135)
Affinity DataEC50:  1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657733BDBM50657733(CHEMBL6142065)
Affinity DataEC50:  1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657748BDBM50657748(CHEMBL6146142)
Affinity DataEC50:  1.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50180850BDBM50180850(CHEMBL3819587)
Affinity DataKd:  1.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657740BDBM50657740(CHEMBL6102862)
Affinity DataEC50:  1.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657752BDBM50657752(CHEMBL6133670)
Affinity DataEC50:  1.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657742BDBM50657742(CHEMBL6159634)
Affinity DataEC50:  1.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657735BDBM50657735(CHEMBL6152957)
Affinity DataEC50:  1.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657749BDBM50657749(CHEMBL6166834)
Affinity DataEC50:  1.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657733BDBM50657733(CHEMBL6142065)
Affinity DataEC50:  1.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657735BDBM50657735(CHEMBL6152957)
Affinity DataEC50:  1.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657756BDBM50657756(CHEMBL6162857)
Affinity DataEC50:  1.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657734BDBM50657734(CHEMBL6152865)
Affinity DataEC50:  1.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657743BDBM50657743(CHEMBL6169496)
Affinity DataEC50:  1.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Mouse)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657019BDBM50657019(CHEMBL6164753)
Affinity DataKd:  1.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657746BDBM50657746(CHEMBL6120920)
Affinity DataEC50:  1.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640677BDBM50640677(CHEMBL5571025)
Affinity DataKi:  1.90nMAssay Description:Inhibition of Keap1-Nrf2 protein-protein interaction (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657753BDBM50657753(CHEMBL6134383)
Affinity DataEC50:  2nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657747BDBM50657747(CHEMBL6160516)
Affinity DataEC50:  2.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657754BDBM50657754(CHEMBL6170527)
Affinity DataEC50:  2.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657743BDBM50657743(CHEMBL6169496)
Affinity DataEC50:  2.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586351BDBM50586351(CHEMBL5075461)
Affinity DataEC50:  2.5nMAssay Description:Modulation of Keap1-Nrf2 protein-protein interaction in human U2OS cells assessed as inhibition of Keap1 by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657738BDBM50657738(CHEMBL6160175)
Affinity DataEC50:  2.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656965BDBM50656965(CHEMBL6132752)
Affinity DataKd:  2.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586347BDBM50586347(CHEMBL5090792)
Affinity DataEC50:  2.90nMAssay Description:Modulation of Keap1-Nrf2 protein-protein interaction in human U2OS cells assessed as inhibition of Keap1 by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Mouse)
Peking Union Medical College and Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657012BDBM50657012(CHEMBL6134103)
Affinity DataKd:  3.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586352BDBM50586352(CHEMBL5079553)
Affinity DataEC50:  3.10nMAssay Description:Modulation of Keap1-Nrf2 protein-protein interaction in human U2OS cells assessed as inhibition of Keap1 by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657748BDBM50657748(CHEMBL6146142)
Affinity DataEC50:  3.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586349BDBM50586349(CHEMBL5085834)
Affinity DataEC50:  3.20nMAssay Description:Modulation of Keap1-Nrf2 protein-protein interaction in human U2OS cells assessed as inhibition of Keap1 by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657751BDBM50657751(CHEMBL6165587)
Affinity DataEC50: >3.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657737BDBM50657737(CHEMBL6164972)
Affinity DataEC50:  3.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657755BDBM50657755(CHEMBL6143596)
Affinity DataEC50:  3.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657268BDBM50657268(CHEMBL6150273)
Affinity DataKi:  3.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006932BDBM50006932(CHEMBL3237245)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human Keap1 KELCH domain (321 to 609 residues) expressed in Escherichia coli BL21 DE3 pLysS cells/Nrf2 (unknown origin) protein-protein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657744BDBM50657744(CHEMBL6150509)
Affinity DataEC50:  3.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657741BDBM50657741(CHEMBL6162135)
Affinity DataEC50:  3.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657736BDBM50657736(CHEMBL6159664)
Affinity DataEC50:  3.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657739BDBM50657739(CHEMBL6149020)
Affinity DataEC50:  3.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657747BDBM50657747(CHEMBL6160516)
Affinity DataEC50:  4.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657750BDBM50657750(CHEMBL6160289)
Affinity DataEC50:  4.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50586350BDBM50586350(CHEMBL5077969)
Affinity DataEC50:  4.5nMAssay Description:Modulation of Keap1-Nrf2 protein-protein interaction in human U2OS cells assessed as inhibition of Keap1 by PathHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657740BDBM50657740(CHEMBL6102862)
Affinity DataEC50:  4.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657745BDBM50657745(CHEMBL6144337)
Affinity DataEC50:  4.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657754BDBM50657754(CHEMBL6170527)
Affinity DataEC50:  4.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50498214BDBM50498214(CHEMBL3423016)
Affinity DataKd:  5nMAssay Description:Binding affinity to Keap1/Nrf2 complex (unknown origin) by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657749BDBM50657749(CHEMBL6166834)
Affinity DataEC50:  5.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657742BDBM50657742(CHEMBL6159634)
Affinity DataEC50:  5.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
The State University of New Jersey

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50657756BDBM50657756(CHEMBL6162857)
Affinity DataEC50:  5.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
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