Compile Data Set for Download or QSAR
Report error Found 485 Enz. Inhib. hit(s) with Target = 'Nicotinic acetylcholine receptor'
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.00900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049750BDBM50049750(CHEMBL59986 | (S)-3-(azetidin-2-ylmethoxy)pyridine...)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50066789BDBM50066789(A-85380,5-Iodo | CHEMBL123433 | A-85380-I | 3-((S)...)
Affinity DataKi:  0.0100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049750BDBM50049750(CHEMBL59986 | (S)-3-(azetidin-2-ylmethoxy)pyridine...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049750BDBM50049750(CHEMBL59986 | (S)-3-(azetidin-2-ylmethoxy)pyridine...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0590nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.0800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049750BDBM50049750(CHEMBL59986 | (S)-3-(azetidin-2-ylmethoxy)pyridine...)
Affinity DataKi:  0.0900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50066789BDBM50066789(A-85380,5-Iodo | CHEMBL123433 | A-85380-I | 3-((S)...)
Affinity DataKi:  0.110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50107863BDBM50107863((1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  0.160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50171347BDBM50171347(A-85380 | CHEMBL190589 | 3-(Azetidin-2-ylmethoxy)-...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50107863BDBM50107863((1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50100712BDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)
Affinity DataKi:  0.330nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.340nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.370nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.390nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606633BDBM50606633(CHEMBL5219936)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50107863BDBM50107863((1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  0.410nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details
PubMed
TargetNicotinic acetylcholine receptor alpha6/alpha3/beta4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50567433BDBM50567433(CHEMBL4869892)
Affinity DataIC50: 0.480nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50054820BDBM50054820([(1S,4S,5R,6S,8R,9R,13S,16S,18S)-11-ethyl-8,9-dihy...)
Affinity DataKi:  0.640nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50107863BDBM50107863((1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  0.710nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624317BDBM50624317(CHEMBL5420268)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at rat alpha9alpha10 nACh receptor expressed in Xenopus oocyte assessed as inhibition of acetylcholine-induced response at -70 mV...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50107863BDBM50107863((1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  0.900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50004108BDBM50004108((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...)
Affinity DataKi:  0.960nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50004108BDBM50004108((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...)
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50004108BDBM50004108((R,S)-nicotine | (RS)-nicotine | nicotine | (+-)-n...)
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50107863BDBM50107863((1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  1.03nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50107863BDBM50107863((1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50049757BDBM50049757((2R,4S)-2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2....)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606635BDBM50606635(CHEMBL5220820)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50107863BDBM50107863((1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624311BDBM50624311(CHEMBL5409922)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at rat alpha9alpha10 nACh receptor expressed in Xenopus oocyte assessed as inhibition of acetylcholine-induced response at -70 mV...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNicotinic acetylcholine receptor alpha6/alpha3/beta4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238606BDBM50238606(CHEMBL4099865)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current at -70 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2019
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606634BDBM50606634(CHEMBL5220229)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNicotinic acetylcholine receptor alpha6/alpha3/beta4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445330BDBM50445330(CHEMBL3104243)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606636BDBM50606636(CHEMBL5220778)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response incubated for 5 mins in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601895BDBM50601895(CHEMBL5192422)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at rat alpha9alpha10 nACh receptor expressed in Xenopus oocyte assessed as inhibition of acetylcholine-induced response at -70 mV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNicotinic acetylcholine receptor alpha6/alpha3/beta4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50567430BDBM50567430(CHEMBL4860756)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha6/alpha3/beta4(Rat)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50567432BDBM50567432(CHEMBL4876825)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha 5 subunit(House fly)
University of California

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50486231BDBM50486231(CHEBI:39177 | CLOTHIANIDINE)
Affinity DataIC50: 1.80nMAssay Description:Displacement of [3H]IMI from nicotinic acetylcholine receptor in Musca domestica (house fly) head membrane after 90 min by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86311BDBM86311(CAS_485-35-8 | NSC_22407 | Cytisine | Cytisine-(-)...)
Affinity DataKi:  1.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2012
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor(Cape York rat)
National Institute On Drug Abuse

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
In Depth
Date in BDB:
11/25/2011
Entry Details
PubMed
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