Compile Data Set for Download or QSAR
Report error Found 157 Enz. Inhib. hit(s) with Target = 'Neuronal acetylcholine receptor; alpha9/alpha10'
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606633BDBM50606633(CHEMBL5219936)
Affinity DataIC50: 0.0500nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606639BDBM50606639(CHEMBL5219016)
Affinity DataIC50: 0.260nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606640BDBM50606640(CHEMBL5220467)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606641BDBM50606641(CHEMBL5219752)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606645BDBM50606645(CHEMBL5220455)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606638BDBM50606638(CHEMBL5220113)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581244BDBM50581244(CHEMBL5086734)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606644BDBM50606644(CHEMBL5219791)
Affinity DataIC50: 0.510nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339937BDBM50339937(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 0.560nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581248BDBM50581248(CHEMBL5090753)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606650BDBM50606650(CHEMBL5219058)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606637BDBM50606637(CHEMBL5220002)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50589246BDBM50589246(CHEMBL5184316)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human nAChR alpha9alpha10 expressed in Xenopus laevis oocytes holding potential of -70 mV by voltage-clamp based electrophysiological m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581243BDBM50581243(CHEMBL5089881)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544003BDBM50544003(CHEMBL4647678)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50624317BDBM50624317(CHEMBL5420268)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human alpha9alpha10 nACh receptor expressed in Xenopus oocyte assessed as inhibition of acetylcholine-induced response at -70 ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339933BDBM50339933(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50514668BDBM50514668(CHEMBL4526368)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage cl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606643BDBM50606643(CHEMBL5218653)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597506BDBM50597506(CHEMBL5190813)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581249BDBM50581249(CHEMBL5073182)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597504BDBM50597504(CHEMBL5177606)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597507BDBM50597507(CHEMBL5176101)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653255BDBM50653255(CHEMBL6102205)
Affinity DataIC50: 3.20nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653256BDBM50653256(CHEMBL6142041)
Affinity DataIC50: 3.30nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544009BDBM50544009(CHEMBL4644407)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339936BDBM50339936(2,2',2''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 3.70nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653259BDBM50653259(CHEMBL6101859)
Affinity DataIC50: 4nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606642BDBM50606642(CHEMBL5220060)
Affinity DataIC50: 4nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653257BDBM50653257(CHEMBL6078731)
Affinity DataIC50: 4nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601896BDBM50601896(CHEMBL5203781)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653257BDBM50653257(CHEMBL6078731)
Affinity DataIC50: 4nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653259BDBM50653259(CHEMBL6101859)
Affinity DataIC50: 4.10nMAssay Description:Displacement of radioligand from human recombinant adenosine A1 receptor at 21 degC after 90 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339934BDBM50339934(1,1'-(3,3'-(biphenyl-4,4'-diyl)bis(propane-3,1-diy...)
Affinity DataIC50: 4.20nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339935BDBM50339935(1,1',1''-(5,5',5''-(benzene-1,3,5-triyl)tris(penta...)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466607BDBM50466607(CHEMBL4293646)
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466614BDBM50466614(CHEMBL4291079)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50642840BDBM50642840(CHEMBL5570016)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at human wild type alpha9alpha10 nAChR expressed in acetylcholine-induced Xenopus laevis oocytes assessed as inhibition of acetyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445328BDBM50445328(CHEMBL3104241)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of alpha9alpha10 (unknown origin) nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50339938BDBM50339938(1,1',1'',1'''-(5,5',5'',5'''-(benzene-1,2,4,5-tetr...)
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at alpha9/alpha10 nAChR expressed in Xenopus oocyte assessed as inhibition of ACh-gated current by voltage clamp electrophysiolog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597499BDBM50597499(CHEMBL5195695)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50544008BDBM50544008(CHEMBL4634686)
Affinity DataIC50: 5.90nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response measured after 5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581246BDBM50581246(CHEMBL5080428)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response by two-e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597517BDBM50597517(CHEMBL5171118)
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50466608BDBM50466608(CHEMBL4285772)
Affinity DataIC50: 6.60nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 80642BDBM80642(CHEMBL191491 | cid_6433339 | MG 624 | MLS002172460...)
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662922BDBM50662922(CHEMBL6171591)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human alpha9alpha10 nAChR expressed in acetylcholine-induced Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced cur...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50653258BDBM50653258(CHEMBL6132723)
Affinity DataIC50: 9.90nMAssay Description:Displacement of radioligand from human recombinant adenosine A2B receptor at 21 degC after 60 mins by cell-based microplate scintillation countingMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/3/2026
Entry Details
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 80642BDBM80642(CHEMBL191491 | cid_6433339 | MG 624 | MLS002172460...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human alpha9alpha10 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh-induced channel current after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
University of Utah

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 80642BDBM80642(CHEMBL191491 | cid_6433339 | MG 624 | MLS002172460...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human CA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
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