Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with Target = 'Myeloid differentiation primary response protein MyD88'
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654250BDBM50654250(CHEMBL6147421)
Affinity DataKd:  1.5nMAssay Description:Agonist activity against S1P1 receptor by cell based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654249BDBM50654249(CHEMBL6142326)
Affinity DataKd:  2.80nMAssay Description:Agonist activity against S1P1 receptor by cell based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621831BDBM50621831(CHEMBL5400811)
Affinity DataKd:  5.30nMAssay Description:Binding affinity to human MyD88 TIR domain assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654248BDBM50654248(CHEMBL6145251)
Affinity DataKd:  5.40nMAssay Description:Agonist activity against S1P1 receptor by cell based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621830BDBM50621830(CHEMBL5433872)
Affinity DataKd:  8nMAssay Description:Binding affinity to human MyD88 TIR domain assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654246BDBM50654246(CHEMBL6150684)
Affinity DataKd:  8.5nMAssay Description:Agonist activity against S1P1 receptor by cell based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654247BDBM50654247(CHEMBL6103250)
Affinity DataKd:  9.20nMAssay Description:Agonist activity against S1P1 receptor by cell based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365463BDBM50365463(CHEMBL1232461)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MYD88 (unknown origin) incubated for 1 hr by colloidal coomassie staining based LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506658BDBM50506658(CHEMBL4577774)
Affinity DataKd:  3.45E+4nMAssay Description:Binding affinity to recombinant human MyD88 TIR domain (157 to 296 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667401BDBM50667401(CHEMBL6192241)
Affinity DataKd:  1.65E+5nMAssay Description:Binding affinity to MYD88 Toll/interleukin-1 receptor domain (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506659BDBM50506659(CHEMBL4467327)
Affinity DataKd:  1.80E+5nMAssay Description:Binding affinity to recombinant human MyD88 TIR domain (157 to 296 residues) expressed in Escherichia coli BL21(DE3) by surface plasmon resonance ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMyeloid differentiation primary response protein MyD88(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50654245BDBM50654245(CHEMBL6142201)
Affinity DataKd:  1.30E+8nMAssay Description:Agonist activity against S1P1 receptor by cell based FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed