Report error Found 984 Enz. Inhib. hit(s) with Target = 'Macrophage migration inhibitory factor'
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKd: 1.90nMAssay Description:Binding affinity to human MIF incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 6.92nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 7.24nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 9.55nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 10.5nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 11.2nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 12.3nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 12.6nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny...More data for this Ligand-Target Pair
3D Structure (crystal)TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of recombinant human MIF tautomerase activity using 4-hydroxyphenyl pyruvic acid (HPP) as substrate pre-incubated for 30 mins and followed...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Binding affinity to C-terminal His-tagged recombinant human MIF expressed in Escherichia coli BL21 (DE3) at 200 nM by fluorescence assayMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 18.6nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 18.6nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 20.9nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 22.9nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Data obtained for the Example compounds, obtained using the methods described in Example B.More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using 4-hydroxyphenyl pyruvic acid (HPP) as substrate, largely following previously report...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 23.4nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 25.7nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 28.8nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 31.6nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Data obtained for the Example compounds, obtained using the methods described in Example B.More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using 4-hydroxyphenyl pyruvic acid (HPP) as substrate, largely following previously report...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 36.3nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Inhibition of recombinant human MIF tautomerase activity using 4-hydroxyphenyl pyruvic acid (HPP) as substrate pre-incubated for 30 mins and followed...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 37nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Inhibition of human recombinant MIF tautomeraseMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of human MIF tautomerase activity expressed in Escherichia coli BL21 (DE3) using 4-hydroxyphenyl pyruvic acid as substrateMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
TargetMacrophage migration inhibitory factor(Plasmodium falciparum (isolate 3D7))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human His-tagged MIF tautomerization expressed in Escherichia coli BL21 (DE3) using D-dopachrome as substrate after 10 mins...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Plasmodium falciparum (isolate 3D7))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Data obtained for the Example compounds, obtained using the methods described in Example B.More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using 4-hydroxyphenyl pyruvic acid (HPP) as substrate, largely following previously report...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Plasmodium falciparum (isolate 3D7))
Yale University
Curated by ChEMBL
Yale University
Curated by ChEMBL
Affinity DataKi: 43nMAssay Description:Inhibition of recombinant Plasmodium falciparum MIF expressed in Escherichia coli BL21 (DE3) assessed as ketonization of enol form of 4-HPP substrate...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:Data obtained for the Example compounds, obtained using the methods described in Example B.More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using 4-hydroxyphenyl pyruvic acid (HPP) as substrate, largely following previously report...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataIC50: 46.8nMAssay Description:Assays were performed in small-volume clear-bottom black 96 or 384-well polystyrene plates (Greiner Bio-One). First, 2 μL of the enzyme solution...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Human)
University of Electronic Science and Technology of China
Curated by ChEMBL
University of Electronic Science and Technology of China
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
