Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with Target = 'Integrin alpha-M'
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632658BDBM50632658(CHEMBL5417237)
Affinity DataIC50: 47nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632658BDBM50632658(CHEMBL5417237)
Affinity DataIC50: 53nMAssay Description:Antagonist activity at alphaMbeta2 integrin receptor in human HL-60 cells assessed as inhibition of fibrinogen-induced cell adhesion pre-incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462087BDBM50462087(CHEMBL4243248)
Affinity DataIC50: 140nMAssay Description:Inhibition of C3bi-AP binding to CR3 derived from human PMNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632657BDBM50632657(CHEMBL5419935)
Affinity DataIC50: 244nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 75309BDBM75309(cid_5709759 | SMR000718614 | MLS001032120 | (2Z)-3...)
Affinity DataIC50: 330nMAssay Description:Inhibition of C3bi-AP binding to CR3 derived from human PMNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632657BDBM50632657(CHEMBL5419935)
Affinity DataIC50: 353nMAssay Description:Antagonist activity at alphaMbeta2 integrin receptor in human HL-60 cells assessed as inhibition of fibrinogen-induced cell adhesion pre-incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50074661BDBM50074661((S)-1-{(S)-2-[(S)-3-Carboxy-2-((S)-4-methyl-2-{2-[...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632655BDBM50632655(CHEMBL5410616)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632656BDBM50632656(CHEMBL5408335)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632654BDBM50632654(CHEMBL5395825)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50462087BDBM50462087(CHEMBL4243248)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at CR3 in carboxyfluorescein diacetate succiminidyl ester-labeled human PMN assessed as inhibition of TNF/PMA-stimulated adhesion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 75309BDBM75309(cid_5709759 | SMR000718614 | MLS001032120 | (2Z)-3...)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at CR3 in carboxyfluorescein diacetate succiminidyl ester-labeled human PMN assessed as inhibition of TNF/PMA-stimulated adhesion...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632654BDBM50632654(CHEMBL5395825)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaMbeta2 integrin receptor in human HL-60 cells assessed as inhibition of fibrinogen-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632655BDBM50632655(CHEMBL5410616)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaMbeta2 integrin receptor in human HL-60 cells assessed as inhibition of fibrinogen-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505772BDBM50505772(CHEMBL4589062)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaMbeta2 integrin receptor in human HL-60 cells assessed as inhibition of fibrinogen-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632656BDBM50632656(CHEMBL5408335)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaMbeta2 integrin receptor in human HL-60 cells assessed as inhibition of fibrinogen-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505782BDBM50505782(CHEMBL4586928)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaMbeta2 integrin receptor in human HL-60 cells assessed as inhibition of fibrinogen-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632659BDBM50632659(CHEMBL5437666)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50632660BDBM50632660(CHEMBL5397743)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505772BDBM50505772(CHEMBL4589062)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505782BDBM50505782(CHEMBL4586928)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to alphaMbeta2 integrin receptor (unknown origin) preincubated for 30 mins followed by 30 mins incubation in fibrinogen coated wells...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421810BDBM50421810(CHEMBL5271349)
Affinity DataIC50: 6.50E+3nMAssay Description:Antagonist activity at integrin CD11B/CD18 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378538BDBM50378538(CHEMBL570523)
Affinity DataEC50:  1.05E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50421809BDBM50421809(CHEMBL5278431)
Affinity DataIC50: 1.09E+4nMAssay Description:Antagonist activity at integrin CD11B/CD18 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378536BDBM50378536(CHEMBL572115)
Affinity DataEC50:  1.36E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378547BDBM50378547(CHEMBL569007)
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378540BDBM50378540(CHEMBL583892)
Affinity DataEC50:  1.86E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378546BDBM50378546(CHEMBL585139)
Affinity DataEC50:  2.23E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378537BDBM50378537(CHEMBL584543)
Affinity DataEC50:  2.32E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378544BDBM50378544(CHEMBL570061)
Affinity DataEC50:  3.56E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378539BDBM50378539(CHEMBL570524)
Affinity DataEC50:  4.04E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378542BDBM50378542(CHEMBL569154)
Affinity DataEC50:  4.09E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378543BDBM50378543(CHEMBL571876)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378545BDBM50378545(CHEMBL585545)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378541BDBM50378541(CHEMBL570321)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055896BDBM50055896(CHEMBL22599 | CHEMBL141632 | 3-{2-[3-(4-Carbamimid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mac-1 integrin (alphaM-beta2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-M/beta-2(Human)
University of Bologna

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50055896BDBM50055896(CHEMBL22599 | CHEMBL141632 | 3-{2-[3-(4-Carbamimid...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Mac-1 interaction with ICAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed