Compile Data Set for Download or QSAR
Report error Found 312 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase EHMT1'
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281305BDBM50281305(CHEMBL4162206)
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599565BDBM50599565(CHEMBL5191361)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599563BDBM50599563(CHEMBL5171820)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353128BDBM50353128(CHEMBL1231795)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442107BDBM50442107(CHEMBL2441081)
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GLP (unknown origin) incorporation of tritium-labeled methyl group to biotinylated peptide substrates by Scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GLP (unknown origin) using H3(1-20)-cys as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50442103BDBM50442103(CHEMBL2441082)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300029BDBM50300029(6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)-N-(1-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268879BDBM50268879(CHEMBL4094717)
Affinity DataIC50: 4nMAssay Description:Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268886BDBM50268886(CHEMBL4072211)
Affinity DataIC50: 5nMAssay Description:Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622555BDBM50622555(CHEMBL5410724)
Affinity DataIC50: 5nMAssay Description:Inhibition of GLP (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268910BDBM50268910(CHEMBL4066769)
Affinity DataIC50: 6nMAssay Description:Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512623BDBM50512623(CHEMBL4582775)
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268871BDBM50268871(CHEMBL4100004)
Affinity DataIC50: 6nMAssay Description:Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501525BDBM50501525(CHEMBL4086403)
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501525BDBM50501525(CHEMBL4086403)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501525BDBM50501525(CHEMBL4086403)
Affinity DataIC50: 7nMAssay Description:Inhibition of GLP (unknown origin) using H3(1-20)-cys as substrate by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50281297BDBM50281297(CHEMBL4170114)
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512620BDBM50512620(CHEMBL4461224)
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512644BDBM50512644(CHEMBL4467219)
Affinity DataIC50: 9nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599564BDBM50599564(CHEMBL5201140)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656332BDBM50656332(CHEMBL6142996)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300034BDBM50300034(6,7-dimethoxy-N2,N2-dimethyl-N4-(1-methylpiperidin...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50268909BDBM50268909(CHEMBL4088064)
Affinity DataIC50: 11nMAssay Description:Inhibition of human GLP catalytic domain (951 to 1235 residues) expressed in Escherichia coli BL21 (DE3) using biotinylated H3 (1 to 25 residues) as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599559BDBM50599559(CHEMBL5182385)
Affinity DataIC50: 11nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512624BDBM50512624(CHEMBL4568910)
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50599562BDBM50599562(CHEMBL5204152)
Affinity DataIC50: 11nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501520BDBM50501520(CHEMBL4085546)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446376BDBM50446376(CHEMBL3109630)
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501518BDBM50501518(CHEMBL4093293)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501523BDBM50501523(CHEMBL4063569)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300031BDBM50300031(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-(piperi...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512645BDBM50512645(CHEMBL4532743)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512662BDBM50512662(CHEMBL4464846)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353128BDBM50353128(CHEMBL1231795)
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300032BDBM50300032(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300032BDBM50300032(6,7-Dimethoxy-N-(1-methylpiperidin-4-yl)-2-morphol...)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353131BDBM50353131(CHEMBL1829304)
Affinity DataIC50: 15nMAssay Description:Inhibition of GLP assessed as hydrolysis of S-adenosyl-L-homocysteine after 2 mins by SAHH-coupled fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323813BDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: 15nMAssay Description:Activity at methyl transferase activity GLP by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50560578BDBM50560578(CHEMBL4795328)
Affinity DataIC50: 15nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323813BDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataKi:  15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656333BDBM50656333(CHEMBL6147926)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501519BDBM50501519(CHEMBL4072569)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323813BDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50501533BDBM50501533(CHEMBL4097286)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant GLP catalytic SET domain (982 to 1266 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) codon plus RIL as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT1(Human)
Osaka University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50512643BDBM50512643(CHEMBL4460703)
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Displayed 1 to 50 (of 312 total ) | Next | Last >>
Jump to: