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Report error Found 273 Enz. Inhib. hit(s) with Target = 'Hepatocyte nuclear factor 4-alpha'
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667827BDBM50667827(CHEMBL6188913)
Affinity DataEC50:  6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667819BDBM50667819(CHEMBL6192782)
Affinity DataEC50:  13nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667812BDBM50667812(CHEMBL6189288)
Affinity DataEC50:  14nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667827BDBM50667827(CHEMBL6188913)
Affinity DataKd:  23nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667825BDBM50667825(CHEMBL6188617)
Affinity DataEC50:  30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667826BDBM50667826(CHEMBL6191813)
Affinity DataEC50:  30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667813BDBM50667813(CHEMBL6191139)
Affinity DataEC50:  40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667820BDBM50667820(CHEMBL6193595)
Affinity DataEC50:  41nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667818BDBM50667818(CHEMBL6191053)
Affinity DataEC50:  50nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246946BDBM50246946(5-[(E)-2-Phenylvinyl]-2-hydroxybenzoic acid | CHEM...)
Affinity DataEC50:  60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667817BDBM50667817(CHEMBL6192960)
Affinity DataEC50:  60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667814BDBM50667814(CHEMBL6189697)
Affinity DataEC50:  130nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667811BDBM50667811(CHEMBL6191864)
Affinity DataEC50:  140nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667815BDBM50667815(CHEMBL6193200)
Affinity DataEC50:  150nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667816BDBM50667816(CHEMBL6188842)
Affinity DataEC50:  250nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667824BDBM50667824(CHEMBL6190077)
Affinity DataEC50:  300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667808BDBM50667808(CHEMBL6192869)
Affinity DataIC50: 320nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355011BDBM50355011(CHEMBL1834962)
Affinity DataEC50:  330nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667827BDBM50667827(CHEMBL6188913)
Affinity DataKd:  360nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667807BDBM50667807(CHEMBL6190802)
Affinity DataIC50: 400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 87845BDBM87845(2-butyl-4-thiazolidinecarboxylic acid | cid_313264...)
Affinity DataIC50: 814nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94560BDBM94560(N-cyclohexyl-2-[3-(2-furanyl)-2-oxo-1-quinoxalinyl...)
Affinity DataIC50: 817nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94538BDBM94538(SMR001821229 | 2-[phenyl(1-piperidinyl)methyl]-1-n...)
Affinity DataIC50: 828nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94561BDBM94561(cid_53383152 | SMR002353638 | 2-(2-fluorophenyl)-2...)
Affinity DataIC50: 970nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667821BDBM50667821(CHEMBL6192519)
Affinity DataEC50:  1.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304337BDBM50304337(2-(2-Nitro-naphtho[2,1-b]furan-1-yl)-ethanol | 2-(...)
Affinity DataEC50:  1.22E+3nMAssay Description:Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells co-transfected with LexADBD assessed as increase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50304338BDBM50304338(1-methyl-2-nitronaphtho[2,1-b]furan | 1-Methyl-2-n...)
Affinity DataEC50:  1.28E+3nMAssay Description:Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells co-transfected with LexADBD assessed as increase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667823BDBM50667823(CHEMBL6188824)
Affinity DataEC50:  1.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94585BDBM94585(N-benzyl-2-(4-cyanophenyl)-2-[3-(furan-2-yl)-2-oxo...)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94617BDBM94617(cid_53383173 | N-(2,6-dimethylphenyl)-2-[3-(2-fura...)
Affinity DataIC50: 1.34E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 80725BDBM80725(MLS000756557 | 2,3-bis[(4-methylphenyl)thio]naphth...)
Affinity DataIC50: 1.38E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94517BDBM94517(cid_53383343 | N-tert-butyl-2-[3-(furan-2-yl)-2-ox...)
Affinity DataIC50: 1.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470BDBM50470(MLS000855932 | 2-[[5,6-bis(furan-2-yl)-1,2,4-triaz...)
Affinity DataIC50: 1.42E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22594BDBM22594(7-methoxy-4-nitro-5-oxatricyclo[7.4.0.0^{2,6}]trid...)
Affinity DataEC50:  1.47E+3nMAssay Description:Agonist activity at human full length HNF4alpha nuclear receptor expressed in human HepG2/C3A cells co-transfected with LexADBD assessed as increase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94591BDBM94591(cid_53383347 | N-tert-butyl-2-(4-cyanophenyl)-2-[3...)
Affinity DataIC50: 1.48E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94514BDBM94514(N-cyclohexyl-2-[3-(2-furanyl)-2-oxo-1-quinoxalinyl...)
Affinity DataIC50: 1.48E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 43422BDBM43422(SMR000261043 | cid_2423595 | (E)-2-cyano-3-[3-[(E)...)
Affinity DataIC50: 1.51E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 72328BDBM72328(cid_6377798 | SMR000241969 | ethyl (Z)-3-(4-chloro...)
Affinity DataIC50: 1.56E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 83788BDBM83788(MLS000680483 | 1-benzyl-5-[3-(2-furyl)-2-propen-1-...)
Affinity DataIC50: 1.59E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 40594BDBM40594(SMR000042109 | 2-[[5,6-bis(2-furanyl)-1,2,4-triazi...)
Affinity DataIC50: 1.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94579BDBM94579(N-tert-butyl-2-cyclopropyl-2-[3-(2-furanyl)-2-oxo-...)
Affinity DataIC50: 1.72E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94629BDBM94629(N-cyclohexyl-2-[3-(2-furanyl)-2-oxo-1-quinoxalinyl...)
Affinity DataIC50: 1.75E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94558BDBM94558(N-tert-butyl-2-[3-(2-furanyl)-2-oxo-1-quinoxalinyl...)
Affinity DataIC50: 1.78E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667809BDBM50667809(CHEMBL6190496)
Affinity DataEC50:  1.80E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94549BDBM94549(MLS003674221 | cid_53383346 | N-tert-butyl-2-[3-(f...)
Affinity DataIC50: 1.81E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94506BDBM94506(cid_53383334 | N-cyclohexyl-2-(2-fluorophenyl)-2-[...)
Affinity DataIC50: 1.84E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94627BDBM94627(N-tert-butyl-2-(2-fluorophenyl)-2-[3-(furan-2-yl)-...)
Affinity DataIC50: 1.85E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94534BDBM94534(MLS003674201 | SMR002353669 | 2-(4-cyanophenyl)-N-...)
Affinity DataIC50: 1.86E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94527BDBM94527(MLS003674212 | SMR002353680 | 2-(1-benzofuran-2-yl...)
Affinity DataIC50: 1.86E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
Goethe University Frankfurt

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 94595BDBM94595(MLS000779343 | SMR000416057 | (5Z)-1-[(4-fluorophe...)
Affinity DataIC50: 1.87E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
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