Compile Data Set for Download or QSAR
Report error Found 2436 Enz. Inhib. hit(s) with Target = 'Glutaminyl-peptide cyclotransferase'
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519291BDBM50519291(CHEMBL4462495 | US20240059675, Compound SEN177 | U...)
Affinity DataIC50: 0.0530nMAssay Description:Inhibition of sQC (unknown origin) expressed in Escherichia coli Transetta (DE3) assessed as N-terminal pyroglutamate formation using fluorescent sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581458BDBM50581458(CHEMBL5092802)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 637687BDBM637687(US11834440, Compound RF-1B)
Affinity DataKi:  0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581397BDBM50581397(CHEMBL5085353)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581442BDBM50581442(CHEMBL5086776)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581399BDBM50581399(CHEMBL5085226)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581400BDBM50581400(CHEMBL5075575)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237486BDBM50237486(CHEMBL4077433)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human glutaminyl cyclase assessed as reduction in conversion of H-Gln-AMC hydrobromide to pGlu-AMC preincubated with substrate for 10 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2019
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581426BDBM50581426(CHEMBL5089771)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581398BDBM50581398(CHEMBL5083519)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human recombinant glutaminyl cyclase using H-Gln-AMC hydrobromide as substrate measured after 15 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652300BDBM652300(US20240059675, Example 4)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652305BDBM652305(US20240059675, Example 8)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652305BDBM652305(US20240059675, Example 8)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665642BDBM50665642(CHEMBL6174275)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652305BDBM652305(US20240059675, Example 8)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665643BDBM50665643(CHEMBL6168765)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50658212BDBM50658212(CHEMBL6166405)
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665644BDBM50665644(CHEMBL6160352)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665645BDBM50665645(CHEMBL6166960)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687808BDBM687808(US20240246981, Example 36)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687805BDBM687805(US20240246981, Example 33)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665641BDBM50665641(CHEMBL6147767)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687806BDBM687806(US20240246981, Example 34)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652305BDBM652305(US20240059675, Example 8)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687812BDBM687812(US20240246981, Example 40)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50665646BDBM50665646(CHEMBL6172023)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652318BDBM652318(US20240059675, Example 21)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687832BDBM687832(US20240246981, Example 60)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687830BDBM687830(US20240246981, Example 58)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687830BDBM687830(US20240246981, Example 58)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664877BDBM50664877(CHEMBL6165872)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687835BDBM687835(US20240246981, Example 63)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664878BDBM50664878(CHEMBL6161773)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652324BDBM652324(US20240059675, Example 26)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664879BDBM50664879(CHEMBL6166839)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652324BDBM652324(US20240059675, Example 26)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687833BDBM687833(US20240246981, Example 61)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664874BDBM50664874(CHEMBL6163584)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687834BDBM687834(US20240246981, Example 62)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664875BDBM50664875(CHEMBL6166421)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687834BDBM687834(US20240246981, Example 62)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664876BDBM50664876(CHEMBL6174330)
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652310BDBM652310(US20240059675, Example 13)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652310BDBM652310(US20240059675, Example 13)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687822BDBM687822(US20240246981, Example 50)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687822BDBM687822(US20240246981, Example 50)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687827BDBM687827(US20240246981, Example 55)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687827BDBM687827(US20240246981, Example 55)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase-like protein(Human)
Tongji University Cancer Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 687828BDBM687828(US20240246981, Example 56)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetGlutaminyl-peptide cyclotransferase(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 652312BDBM652312(US20240059675, Example 15)
Affinity DataIC50: 1nMAssay Description:QPCT or QPCTL dependent conversion of N-terminal glutamine to pyroglutamate of CD47 was monitored via MALDI-TOF MS. Test compounds were dissolved in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
US Patent

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