Report error Found 76 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1/2/3/4'
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human Nav1.3 assessed as tonic block by patch-clamp electrophysiology/cell based assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of FGFR (unknown origin) by kinase hotspot assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 4.60nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 6.5nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 7.60nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of FGFR (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of FGFR (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 92nMAssay Description:Inhibitory activity against recombinant human FGFRMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of FGF-stimulated human umbilical vein endothelial cell proliferationMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of FGFR (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of FGFR (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of Fibroblast growth factor receptorMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 573nMAssay Description:Inhibition of FGFR (unknown origin) incubated for 1 hr by mobility shift assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of FGFR in human U-266 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous one solution cell prolifera...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of Fibroblast growth factor receptorMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against fibroblast growth factor receptor (FGFr)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 4.63E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory activity against fibroblast growth factor receptor (FGFr)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibitory activity against fibroblast growth factor receptor (FGFr)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 5.25E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 5.28E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibitory activity against fibroblast growth factor receptor (FGFr)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 5.52E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 6.03E+3nMAssay Description:Inhibition of FGFR in bortezomib Resistant human RPMI-8226 cells assessed as reduction of cell growth incubated for 72 hrs by CellTiter 96 aqueous on...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibitory activity against fibroblast growth factor receptor (FGFr)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 6.33E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetFibroblast growth factor receptor 1/2/3/4(Human)
Shengjing Hospital of China Medical University
Curated by ChEMBL
Shengjing Hospital of China Medical University
Curated by ChEMBL
Affinity DataIC50: 6.35E+3nMAssay Description:Inhibition of FGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars

3D Structure (crystal)













































