Compile Data Set for Download or QSAR
Report error Found 132 Enz. Inhib. hit(s) with Target = 'Exportin-1'
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245464BDBM50245464(CHEBI:52646 | LEPTOMYCIN B)
Affinity DataIC50: 1nMAssay Description:Inhibition of CRM1-mediated nucleocytoplasmic transport in human HeLa cells after 90 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668014BDBM50668014(CHEMBL6190383)
Affinity DataEC50:  1nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667992BDBM50667992(CHEMBL6190154)
Affinity DataEC50:  1.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668013BDBM50668013(CHEMBL6193060)
Affinity DataEC50:  2nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135482BDBM50135482(1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataEC50:  2nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668021BDBM50668021(CHEMBL6191562)
Affinity DataEC50:  2.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640051BDBM50640051(CHEMBL5555068)
Affinity DataEC50:  4nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640055BDBM50640055(CHEMBL5559223)
Affinity DataEC50:  4nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640043BDBM50640043(CHEMBL5556912)
Affinity DataEC50:  4nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667999BDBM50667999(CHEMBL6193273)
Affinity DataEC50:  4.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619732BDBM50619732(CHEMBL3898452)
Affinity DataEC50:  5nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668017BDBM50668017(CHEMBL6193148)
Affinity DataEC50:  5.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135482BDBM50135482(1-(5-Methoxy-2-thiophen-2-yl-quinazolin-4-ylamino)...)
Affinity DataEC50:  5.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640051BDBM50640051(CHEMBL5555068)
Affinity DataEC50:  6nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640022BDBM50640022(CHEMBL5568605)
Affinity DataEC50:  7nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668009BDBM50668009(CHEMBL6191512)
Affinity DataEC50:  7.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668020BDBM50668020(CHEMBL6192152)
Affinity DataEC50:  7.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668005BDBM50668005(CHEMBL6190954)
Affinity DataEC50:  8.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667994BDBM50667994(CHEMBL6190228)
Affinity DataEC50:  9nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667996BDBM50667996(CHEMBL6192172)
Affinity DataEC50:  9.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668018BDBM50668018(CHEMBL6193465)
Affinity DataEC50:  9.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245476BDBM50245476(CHEMBL4088268)
Affinity DataIC50: 10nMAssay Description:Inhibition of CRM1-mediated nucleocytoplasmic transport in human HeLa cells after 90 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668019BDBM50668019(CHEMBL6192106)
Affinity DataEC50:  11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640032BDBM50640032(CHEMBL5542885)
Affinity DataEC50:  11nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668006BDBM50668006(CHEMBL6190907)
Affinity DataEC50:  11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668000BDBM50668000(CHEMBL6191853)
Affinity DataEC50:  12nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527778BDBM50527778(KPT-330 | Selinexor | Xpovio | US20240376114, Comp...)
Affinity DataEC50:  12nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640036BDBM50640036(CHEMBL5566091)
Affinity DataEC50:  13nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668007BDBM50668007(CHEMBL6189754)
Affinity DataEC50:  13nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619732BDBM50619732(CHEMBL3898452)
Affinity DataIC50: 16nMAssay Description:Inhibition of XPO1 in human HPBALL cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667997BDBM50667997(CHEMBL6191728)
Affinity DataEC50:  18nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527778BDBM50527778(KPT-330 | Selinexor | Xpovio | US20240376114, Comp...)
Affinity DataKd:  19nMAssay Description:Binding affinity to recombinant His-tagged CRM1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640020BDBM50640020(CHEMBL5560534)
Affinity DataEC50:  19nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668015BDBM50668015(CHEMBL6193008)
Affinity DataEC50:  20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640031BDBM50640031(CHEMBL5564554)
Affinity DataEC50:  21nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668008BDBM50668008(CHEMBL6191609)
Affinity DataEC50:  23nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640042BDBM50640042(CHEMBL5563530)
Affinity DataEC50:  23nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640021BDBM50640021(Verdinexor | KPT-335)
Affinity DataEC50:  24nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581761BDBM50581761(CHEMBL5093328)
Affinity DataKd:  24nMAssay Description:Binding affinity to Cy3 dye-labelled human CRM1 assessed as dissociation constant in absence of RanGTP at 10 uM incubated for 1 hr by micro-scale the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640029BDBM50640029(CHEMBL5562376)
Affinity DataEC50:  24nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668016BDBM50668016(CHEMBL6193449)
Affinity DataEC50:  25nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640050BDBM50640050(CHEMBL5542505)
Affinity DataEC50:  25nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245473BDBM50245473(CHEMBL4077955)
Affinity DataIC50: 25nMAssay Description:Inhibition of CRM1-mediated nucleocytoplasmic transport in human HeLa cells after 90 mins by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2019
Entry Details Article
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50640041BDBM50640041(CHEMBL5542934)
Affinity DataEC50:  26nMAssay Description:Inhibition of XPO1 in human Jurkat cells assessed as suppression of IL-2 expression incubated for 6 hrs by Bright-Glo Luciferase based microplate rea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527779BDBM50527779(CHEMBL4440028)
Affinity DataKd:  27nMAssay Description:Binding affinity to recombinant His-tagged CRM1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668037BDBM50668037(CHEMBL6192966)
Affinity DataEC50:  29nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668034BDBM50668034(CHEMBL6188931)
Affinity DataEC50:  30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668024BDBM50668024(CHEMBL6193567)
Affinity DataEC50:  31nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668031BDBM50668031(CHEMBL6191061)
Affinity DataEC50:  34nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetExportin-1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50527778BDBM50527778(KPT-330 | Selinexor | Xpovio | US20240376114, Comp...)
Affinity DataIC50: 34nMAssay Description:Inhibition of XPO1 in human MOLT-16 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
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