Compile Data Set for Download or QSAR
Report error Found 415 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor [1-770,'NPG',771-1210]'
TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.180nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791298BDBM791298(rel-(R)-3-phenyl-2-(3-((1-(vinylsulfonyl)azetidin-...)
Affinity DataIC50: 0.262nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791196BDBM791196(3-(3-chlorophenyl)-2-(3-{[(2S)-1-(ethenesulfonyl)p...)
Affinity DataIC50: 0.290nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791192BDBM791192(2-(3-{[(2S)-1-(ethenesulfonyl)pyrrolidin-2-yl]meth...)
Affinity DataIC50: 0.308nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791267BDBM791267(2-(3-{[(2S,4S)-1-(ethenesulfonyl)-4-methylpyrrolid...)
Affinity DataIC50: 0.330nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 569189BDBM569189(US11427559, Compound A)
Affinity DataKd: <0.5nMAssay Description:In some assays, kinase-tagged T7 phage strains were prepared in an E. coli host derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791261BDBM791261(3-[3-(difluoromethoxy)-4-fluorophenyl]-2-(3-{[(2S)...)
Affinity DataIC50: 0.537nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 790077BDBM790077({[(10S,17E)-14-(2-hydroxyethyl)- 8,10,12-trimethyl...)
Affinity DataIC50: 0.650nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791292BDBM791292(2-(3-{[(2S)-1-(ethenesulfonyl)pyrrolidin-2-yl]meth...)
Affinity DataIC50: 0.706nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791269BDBM791269(1-[(2S)-4-fluoro-2-({[4-(3-phenyl-1H-pyrrolo[3,2-b...)
Affinity DataIC50: 0.724nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 790106BDBM790106(2-[(8aR,9R,19E)-1-ethoxy-9,11-dimethyl- 7,8,8a,9,1...)
Affinity DataIC50: 0.730nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791185BDBM791185(N-[2-({4-[3-(3-chlorophenyl)-1H-pyrrolo[3,2-b]pyri...)
Affinity DataIC50: 0.801nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791238BDBM791238(1-{(2S)-2-[({4-[3-(1-benzofuran-6-yl)-1H-pyrrolo[3...)
Affinity DataIC50: 0.837nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791271BDBM791271(1-[(2S)-2-({[4-(3-phenyl-1H-pyrrolo[3,2-b]pyridin-...)
Affinity DataIC50: 0.875nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 790007BDBM790007(2-[(10S,17E)-8,10,16-trimethyl-12- (propan-2-yl)-2...)
Affinity DataIC50: 0.910nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791268BDBM791268(1-[(2S)-4,4-difluoro-2-({[4-(3-phenyl-1H-pyrrolo[3...)
Affinity DataIC50: 0.979nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791197BDBM791197(1-{(2S)-2-[({4-[3-(3-chlorophenyl)-1H-pyrrolo[3,2-...)
Affinity DataIC50: 0.988nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791194BDBM791194(2-(3-{[(2S)-1-(ethenesulfonyl)pyrrolidin-2-yl]meth...)
Affinity DataIC50: 1.05nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 557852BDBM557852(US11365189, Ex. No. 6 | 1-(3-((4-((3,4-dichloro-2-...)
Affinity DataIC50: 1.10nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 790005BDBM790005((10R,16E)-3-methyl-13-(1- methylpiperidin-4-yl)-3,...)
Affinity DataIC50: 1.12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791258BDBM791258(1-{(2S)-2-[({4-[3-(3-ethynylphenyl)-1H-pyrrolo[3,2...)
Affinity DataIC50: 1.29nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791237BDBM791237(1-{(2S)-2-[({4-[3-(1-benzothiophen-6-yl)-1H-pyrrol...)
Affinity DataIC50: 1.29nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791296BDBM791296(rel-(R)-1-(2-(((4-(3-phenyl-1H-pyrrolo[3,2-b]pyrid...)
Affinity DataIC50: 1.33nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791294BDBM791294(3-(5-chloro-2-fluorophenyl)-2-(3-{[(2S)-1-(ethenes...)
Affinity DataIC50: 1.36nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 790100BDBM790100(2-{(10S,17E)-12-ethyl-8,10-dimethyl-16- [(propan-2...)
Affinity DataIC50: 1.39nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791293BDBM791293(1-{(2S)-2-[({4-[3-(5-chloro-2-fluorophenyl)-7-meth...)
Affinity DataIC50: 1.55nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 790061BDBM790061(2-[(10S,17E)-16-ethoxy-12-ethyl-8,10- dimethyl-2,8...)
Affinity DataIC50: 1.56nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791215BDBM791215(N-{2-[(4-{3-[2-fluoro-5-(trifluoromethyl)phenyl]-1...)
Affinity DataIC50: 1.60nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 790026BDBM790026(2-[(10S,17E)-12-ethyl-8,10,16-trimethyl- 2,8,10,11...)
Affinity DataIC50: 1.62nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791186BDBM791186(N-[2-({4-[3-(1H-indol-6-yl)-1H-pyrrolo[3,2-b]pyrid...)
Affinity DataIC50: 1.82nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791291BDBM791291(1-[(2S)-2-({[4-(7-methyl-3-phenyl-1H-pyrrolo[3,2-b...)
Affinity DataIC50: 1.83nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791236BDBM791236(1-{(2S)-2-[({4-[3-(naphthalen-2-yl)-1H-pyrrolo[3,2...)
Affinity DataIC50: 1.86nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791189BDBM791189(N-ethyl-N-(2-{[4-(3-phenyl-1H-pyrrolo[3,2-b]pyridi...)
Affinity DataIC50: 1.92nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791233BDBM791233(1-{(2S)-2-[({4-[3-(2-fluoro-5-methylphenyl)-1H-pyr...)
Affinity DataIC50: 1.97nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 557849BDBM557849(US11365189, Ex. No. 3 | 1-(3-((4-((3,4-dichlorophe...)
Affinity DataIC50: 2nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791216BDBM791216(N-[2-({4-[3-(5-chloro-2-fluorophenyl)-1H-pyrrolo[3...)
Affinity DataIC50: 2.02nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791190BDBM791190(1-[(2S)-2-({[4-(3-phenyl-1H-pyrrolo[3,2-b]pyridin-...)
Affinity DataIC50: 2.06nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791181BDBM791181(N-methyl-N-(2-{[4-(3-phenyl-1H-pyrrolo[3,2-b]pyrid...)
Affinity DataIC50: 2.08nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791297BDBM791297(rel-(S)-3-phenyl-2-(3-((1-(vinylsulfonyl)azetidin-...)
Affinity DataIC50: 2.21nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791220BDBM791220(N-[2-({4-[3-(2-fluoro-5-methylphenyl)-1H-pyrrolo[3...)
Affinity DataIC50: 2.21nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 50468247BDBM50468247(HM 781-36B | HM-781-36B | NOV-120101 | Poziotinib ...)
Affinity DataIC50: 2.30nMAssay Description:Cell viability was determined using the Cell Titer Glo assay (Promega) as previously described. Briefly, 2000-3000 cells per well were plated in 384-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791245BDBM791245(1-{(2S)-2-[({4-[3-(2-fluorophenyl)-1H-pyrrolo[3,2-...)
Affinity DataIC50: 2.31nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791264BDBM791264(2-(3-{[(2S)-1-(ethenesulfonyl)pyrrolidin-2-yl]meth...)
Affinity DataIC50: 2.41nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 731065BDBM731065(US20250122202, Example 115)
Affinity DataIC50: 2.46nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 790039BDBM790039(2-[(10S,17E)-16-ethoxy-8,10-dimethyl- 12-(propan-2...)
Affinity DataIC50: 2.55nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2026
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 731067BDBM731067(US20250122202, Example 104)
Affinity DataIC50: 2.72nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791217BDBM791217(N-[2-({4-[3-(2,5-difluorophenyl)-1H-pyrrolo[3,2-b]...)
Affinity DataIC50: 2.82nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 730779BDBM730779(US20250122202, Example 60)
Affinity DataIC50: 2.82nMAssay Description:The compound of the present invention had a good inhibitory activity on an EGFR kinase, and the IC50 values were all less than 10 μM. The specific ex...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791198BDBM791198(1-{(2S)-2-[({4-[3-(5-chloro-2-fluorophenyl)-1H-pyr...)
Affinity DataIC50: 2.84nMAssay Description:TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

TargetEpidermal growth factor receptor [1-770,'NPG',771-1210](Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 791234BDBM791234(1-{(2S)-2-[({4-[3-(3-ethylphenyl)-1H-pyrrolo[3,2-b...)
Affinity DataIC50: 2.92nMAssay Description:Compounds were tested on human Nav1.7 (hNav1.7) expressed stably in 293 cells, which have no endogenous sodium channels. Two forms of whole-cell patc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/17/2026
Entry Details US Patent

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