Compile Data Set for Download or QSAR
Report error Found 372 Enz. Inhib. hit(s) with Target = 'Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A'
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634040BDBM50634040(CHEMBL5437525)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PDE11A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126462BDBM50126462((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-{(R)-1-[2-(1-m...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126462BDBM50126462((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-{(R)-1-[2-(1-m...)
Affinity DataIC50: 1.40nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126452BDBM50126452((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-pyri...)
Affinity DataIC50: 2nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126455BDBM50126455((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-pyri...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458313BDBM50458313(CHEMBL4217054)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of N-terminal GST-tagged full length recombinant human PDE11A expressed in Baculovirus infected Sf9 insect cells using FAM-cAMP as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126467BDBM50126467((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-{(R)-1-[2-(1H-...)
Affinity DataIC50: 3.5nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50467473BDBM50467473(CHEMBL4292389)
Affinity DataIC50: 4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE11A4 expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126464BDBM50126464((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-pyra...)
Affinity DataIC50: 4.20nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126453BDBM50126453(3-[(R)-3-((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-1,4-di...)
Affinity DataIC50: 4.30nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126449BDBM50126449(3-[(R)-3-((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-1,4-di...)
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126456BDBM50126456((6R,12aR)-2-[(R)-1-(3-Azetidin-1-yl-3-oxo-propyl)-...)
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50458314BDBM50458314(CHEMBL4217579)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of N-terminal GST-tagged full length recombinant human PDE11A expressed in Baculovirus infected Sf9 insect cells using FAM-cAMP as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126458BDBM50126458((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-((R)-1-benzyl-...)
Affinity DataIC50: 5.5nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126463BDBM50126463((6R,12aR)-2-((R)-1-Benzyl-pyrrolidin-3-yl)-6-p-tol...)
Affinity DataIC50: 6.5nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126451BDBM50126451((6R,12aR)-2-((R)-1-Benzyl-pyrrolidin-3-yl)-6-(4-me...)
Affinity DataIC50: 6.70nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335827BDBM50335827((6R,12aR)6-(2,4-Dichlorophenyl)-2-ethyl-2,3,6,7,12...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant PDE11A-mediated hydrolysis of cGMP after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126461BDBM50126461((6R,12aR)-2-((R)-1-Benzyl-pyrrolidin-3-yl)-6-(3-me...)
Affinity DataIC50: 11.8nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634053BDBM50634053(CHEMBL5432407)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126461BDBM50126461((6R,12aR)-2-((R)-1-Benzyl-pyrrolidin-3-yl)-6-(3-me...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634053BDBM50634053(CHEMBL5432407)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634053BDBM50634053(CHEMBL5432407)
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) extracted from Sf9 insect cells using cAMP as substrate pre-incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662675BDBM50662675(CHEMBL6173500)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662676BDBM50662676(CHEMBL6142827)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662661BDBM50662661(CHEMBL6163944)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50634053BDBM50634053(CHEMBL5432407)
Affinity DataIC50: 16nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14777BDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126457BDBM50126457((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(3-meth...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14777BDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 22nMAssay Description:Inhibition of N-terminal GST-tagged human PDE11A4 expressed in baculovirus infected sf9 cells using [3H]cGMP as substrate measured after 30 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14777BDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PDE11A4 (1 to 943 residues) expressed in Sf9 insect cells using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662670BDBM50662670(CHEMBL6170834)
Affinity DataIC50: 27nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662671BDBM50662671(CHEMBL6176945)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126468BDBM50126468((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-((R)-1-hexyl-p...)
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14777BDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human phosphodiesterase 11More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662662BDBM50662662(CHEMBL6175036)
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272569BDBM50272569(CHEMBL4128481)
Affinity DataIC50: 35nMAssay Description:Inhibition of full length recombinant human PDE11A4 using 3',5'-[3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662681BDBM50662681(CHEMBL6168839)
Affinity DataIC50: 36nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14777BDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 37nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126471BDBM50126471((6R,12aR)-2-((R)-1-Benzyl-pyrrolidin-3-yl)-6-(6-ox...)
Affinity DataIC50: 39nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50459162BDBM50459162(CHEMBL4218772)
Affinity DataIC50: 39nMAssay Description:Inhibition of PDE11A catalytic domain (588 to 911 residues) (unknown origin) expressed in Escherichia coli BL21 using 3H-cAMP as substrate after 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662679BDBM50662679(CHEMBL6170922)
Affinity DataIC50: 39nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662672BDBM50662672(CHEMBL6171500)
Affinity DataIC50: 41nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662685BDBM50662685(CHEMBL6175530)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662678BDBM50662678(CHEMBL6174438)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126466BDBM50126466((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-2-[(R)-1-(2-cycl...)
Affinity DataIC50: 43nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662682BDBM50662682(CHEMBL6169545)
Affinity DataIC50: 44nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662684BDBM50662684(CHEMBL6169979)
Affinity DataIC50: 45nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14777BDBM14777(CHEMBL779 | (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-m...)
Affinity DataIC50: 47nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE11A4 expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662680BDBM50662680(CHEMBL6166825)
Affinity DataIC50: 47nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Montclair State University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126470BDBM50126470(3-[(R)-3-((6R,12aR)-6-Benzo[1,3]dioxol-5-yl-1,4-di...)
Affinity DataIC50: 48nMAssay Description:Inhibitory activity against phosphodiesterase 11 (PDE11) obtained from recombinant Sf9 expressionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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