Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with Target = 'Dimer of Retinoic acid receptor RXR-alpha'
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandChemical structure of BindingDB Monomer ID 50032675BDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  18nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandChemical structure of BindingDB Monomer ID 50032675BDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataKd:  28nMpH: 7.4 T: 2°CAssay Description:Binding assay using human retinoid X receptor alpha (RXR).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandChemical structure of BindingDB Monomer ID 50391814BDBM50391814(CHEMBL2146901)
Affinity DataKd:  330nMAssay Description:Binding affinity to human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer assessed as dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandChemical structure of BindingDB Monomer ID 50032675BDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataIC50: 389nMAssay Description:Displacement of CU-6PMN from human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandChemical structure of BindingDB Monomer ID 50339081BDBM50339081(6-[Ethyl-(3-isobutoxy-4-isopropylphenyl)amino]nico...)
Affinity DataIC50: 394nMAssay Description:Displacement of CU-6PMN from human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandChemical structure of BindingDB Monomer ID 50391814BDBM50391814(CHEMBL2146901)
Affinity DataIC50: 431nMAssay Description:Displacement of CU-6PMN from human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandChemical structure of BindingDB Monomer ID 50030474BDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataKd:  650nMAssay Description:Binding affinity to human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer assessed as dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDimer of Retinoic acid receptor RXR-alpha(Human)
University of Texas Southwestern Medical Center

LigandChemical structure of BindingDB Monomer ID 50210259BDBM50210259(all-cis-docosa-4,7,10,13,16,19-hexaenoic acid | Do...)
Affinity DataIC50: 4.82E+3nMAssay Description:Displacement of CU-6PMN from human PPARgamma-LBD (206 to 477 residues)/human RXRalpha-LBD (224 to 462 residues) heterodimer incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed