Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'DNA-binding protein Ikaros/Protein cereblon'
TargetDNA-binding protein Ikaros/Protein cereblon(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50476157BDBM50476157(CHEMBL6074489)
Affinity DataEC50:  35nMAssay Description:Inhibition of TRKA (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetDNA-binding protein Ikaros/Protein cereblon(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 730416BDBM730416(US20250122166, Compound 7)
Affinity DataEC50:  120nMAssay Description:Inhibition of TIE2 (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetDNA-binding protein Ikaros/Protein cereblon(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 292744BDBM292744(US20260014133, Compound 5)
Affinity DataEC50:  650nMAssay Description:Inhibition of TRKB (unknown origin) by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetDNA-binding protein Ikaros/Protein cereblon(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50557457BDBM50557457(CHEMBL4742712)
Affinity DataEC50: >1.00E+4nMAssay Description:Protac activity at CRBN/IKZF1 (unknown origin) assessed as IKZF1 degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed