Compile Data Set for Download or QSAR
Report error Found 844 Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A'
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608338BDBM50608338(CHEMBL5268427)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226181BDBM50226181(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568726BDBM50568726(CHEMBL4854181 | US12258342, Example 9)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608668BDBM50608668(CHEMBL5282942)
Affinity DataIC50: 0.950nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613099BDBM50613099(CHEMBL5288212)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATP by ethidium bromide staining based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608666BDBM50608666(CHEMBL5267457)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274136BDBM50274136(CHEMBL4126781)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274145BDBM50274145(CHEMBL4127930)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274126BDBM50274126(CHEMBL4127938)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274128BDBM50274128(CHEMBL4127899)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274129BDBM50274129(CHEMBL4126667)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274133BDBM50274133(CHEMBL4129139)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274134BDBM50274134(CHEMBL4128711)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608667BDBM50608667(CHEMBL5271201)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50494813BDBM50494813(CHEMBL3094348)
Affinity DataIC50: 2.38nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274135BDBM50274135(CHEMBL4129934)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as relaxation of pBR322 DNA by supercoiling assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568725BDBM50568725(CHEMBL4873935 | US12258342, Example 1)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274127BDBM50274127(CHEMBL4129335)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21690BDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266345BDBM50266345(CHEMBL4094690)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646753BDBM50646753(CHEMBL5590170)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase using relaxed pBR322 DNA as substrate incubated for 30 mins by ethidium bromide staining based agarose...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266347BDBM50266347(CHEMBL4070524)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226181BDBM50226181(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572196BDBM50572196(CHEMBL4879265)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266348BDBM50266348(CHEMBL4064539)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266393BDBM50266393(CHEMBL4099988)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572198BDBM50572198(CHEMBL4873479)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572198BDBM50572198(CHEMBL4873479)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling incubated for 30 mins in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50226181BDBM50226181(Carbamic acid 5-hydroxy-6-{4-hydroxy-3-[4-hydroxy-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266374BDBM50266374(CHEMBL4099469)
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572194BDBM50572194(CHEMBL4862136)
Affinity DataIC50: 6nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50613606BDBM50613606(CHEMBL4555272)
Affinity DataIC50: 6nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330317BDBM50330317(5-Methyl-1H-pyrrole-2-carboxylic acid (3R,4S,5R,6S...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase supercoiling activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50572195BDBM50572195(CHEMBL4868908)
Affinity DataIC50: 7nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24609BDBM24609(3-ethyl-1-[7-(pyridin-2-yl)-5-(pyridin-3-yl)-1H-1,...)
Affinity DataKi:  7nM ΔG°:  -47.3kJ/molepH: 7.5 T: 2°CAssay Description:Enzymatic hydrolysis of ATP to ADP was coupled to the conversion of NADH to NAD+. The decrease in NADH absorbance was monitored at 340 nm for 20 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50274132BDBM50274132(CHEMBL4127740)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in relaxation of pBR322 DNA by SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518949BDBM50518949(CHEMBL4448131)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus DNA gyraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266344BDBM50266344(CHEMBL4061762)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266351BDBM50266351(CHEMBL4096181)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266352BDBM50266352(CHEMBL4086015)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266355BDBM50266355(CHEMBL4066198)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266342BDBM50266342(CHEMBL4101490)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266356BDBM50266356(CHEMBL4074808)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266378BDBM50266378(CHEMBL4066059)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24606BDBM24606(methyl 2-[(ethylcarbamoyl)amino]-5-(pyridin-3-yl)-...)
Affinity DataKi:  8nM ΔG°:  -47.0kJ/molepH: 7.5 T: 2°CAssay Description:Enzymatic hydrolysis of ATP to ADP was coupled to the conversion of NADH to NAD+. The decrease in NADH absorbance was monitored at 340 nm for 20 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2008
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266379BDBM50266379(CHEMBL4083966)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266349BDBM50266349(CHEMBL4092234)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266350BDBM50266350(CHEMBL4091332)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Weifang Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50266394BDBM50266394(CHEMBL4070393)
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus N-terminal His6-tagged DNA gyrase subunit GyrA/GyrB supercoiling activity expressed in Escherichia coli BL21 (DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2020
Entry Details Article
PubMed
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