Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with Target = 'DNA (cytosine-5)-methyltransferase 3-like/3B'
TargetDNA (cytosine-5)-methyltransferase 3-like/3B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 588052BDBM588052((2R)-7-chloro-2-[trans-4-(dimethylamino)cyclohexyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DNMT3b/DNMT3L catalytic domain using lambda DNA and [3H]SAM as substrate incubated for 30 mins to 1 hr by HotSpot kinase assayMore data for this Ligand-Target Pair
Ligand InfoPurchaseSimilars
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like/3B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590375BDBM50590375(CHEMBL5187396)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DNMT3b/DNMT3L catalytic domain using lambda DNA and [3H]SAM as substrate incubated for 30 mins to 1 hr by HotSpot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like/3B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641350BDBM50641350(CHEMBL5575739)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of DNMT3B/3L (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like/3B(Human)
Daiichi Sankyo Co., Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 11979BDBM11979(MgrA inhibitor, 1 | CHEMBL115145 | 5-[(3-carboxy-4...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of DNMT3B/3L (unknown origin) using poly(2'-deoxyinosinic-2'-deoxycytidylic acid) as substrate after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed