Compile Data Set for Download or QSAR
Report error Found 154 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 3'
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 12621BDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of CDK3 (unknown origin) by kinase selectivity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 12621BDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataKd:  3.20nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193093BDBM50193093(RGB-286638)
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511926BDBM50511926(CHEMBL4442620)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK3 (unknown origin) expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of CDK3/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511926BDBM50511926(CHEMBL4442620)
Affinity DataIC50: 9nMAssay Description:Inhibition of CDK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 454542BDBM454542(US10717746, Example 25 | US10717746, Example 84)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK3 (unknown origin) in presence of 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50528817BDBM50528817(CHEMBL4462530 | US10717746, Example 14 | US2023041...)
Affinity DataIC50: 23nMAssay Description:Inhibition of CDK3 (unknown origin) in presence of 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50511931BDBM50511931(CHEMBL4579344)
Affinity DataIC50: 29nMAssay Description:Inhibition of CDK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31096BDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  30nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  30nMAssay Description:Binding constant for full-length CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  30nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5931BDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataKd:  56nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5931BDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataKd:  56nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5931BDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataKd:  56nMAssay Description:Binding constant for full-length CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataIC50: 58nMAssay Description:Inhibition of CDK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24654BDBM24654(pyrazole diamide, 33 | 4-N-(2,6-dichlorobenzene)-3...)
Affinity DataKd:  60nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50660187BDBM50660187(CHEMBL5086595)
Affinity DataIC50: 69nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312990BDBM50312990((R,S)-3-(3-(2,3-dihydroxypropylamino)phenyl)-4-(5-...)
Affinity DataKd:  80nMAssay Description:Inhibition of CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  82nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  82nMAssay Description:Binding constant for full-length CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 454519BDBM454519(US10717746, Example 2)
Affinity DataIC50: 84nMAssay Description:Inhibition of CDK3 (unknown origin) in presence of 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  134nMAssay Description:Binding affinity to human CDK3 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  140nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  180nMAssay Description:Binding constant for full-length CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  180nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 164883BDBM164883(US9067888, 33)
Affinity DataIC50: 219nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 124970BDBM124970(US8765747, 2)
Affinity DataKd:  250nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50646817BDBM50646817(CHEMBL5591779)
Affinity DataIC50: 370nMAssay Description:Inhibition of CDK3 (unknown origin) using ULight 4EBP1 peptide as substrate incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31099BDBM31099(CHEMBL45741 | Flavopiridol | cid_24867231 | 2-(2-c...)
Affinity DataKd:  410nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5655BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKd:  410nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5655BDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataKd:  410nMAssay Description:Binding constant for full-length CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308060BDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  420nMAssay Description:Binding affinity to CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308060BDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  420nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50601390BDBM50601390(CHEMBL5177698)
Affinity DataIC50: 870nMAssay Description:Inhibition of CDK3 in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193090BDBM50193090(CHEMBL3895785)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of CDK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50128285BDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50593922BDBM50593922(CHEMBL5199065)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CDK3 (unknown origin) incubated for 120 mins in presence of ATP by HotSpot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404389BDBM50404389(CHEMBL5285499)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CDK3 (unknown origin) incubated for 120 mins in presence of ATP by HotSpot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50267607BDBM50267607(3-(5-Bromo-1-methyl-1H-indol-3-yl)-4-(6-hydroxymet...)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of CDK3/Cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 164884BDBM164884(US9067888, 34)
Affinity DataIC50: 1.45E+3nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details
US Patent

TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50609501BDBM50609501(CHEMBL5288241)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of CDK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15138BDBM15138(Biochemistry 469551 Compound 11 | 5-indazolyl pyri...)
Affinity DataKd:  2.70E+3nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataKd:  3.80E+3nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519158BDBM50519158(CHEMBL4445812)
Affinity DataKd:  8.02E+3nMAssay Description:Binding affinity to wild-type human full length CDK3 (M1 to H305 residues) expressed in bacterial expression system measured after 1 hr by kinomescan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13530BDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for CDK3 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32362BDBM32362(cid_11617559 | GW-2580 | 5-[[3-methoxy-4-[(4-metho...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for full-length CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26474BDBM26474(GW-786034 | JMC514632 Compound 13 | 5-({4-[(2,3-di...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for full-length CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13530BDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for full-length CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5445BDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for full-length CDK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
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