Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with Target = 'CDK1/Cyclin E'
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of CDK1/cyclin E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2020
Entry Details Article
PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human CDK1/cyclinE using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 130909BDBM130909(US8822500, Stauro- sporine | US9920060, Staurospor...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human CDK1/cyclin E using RB Protein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition and measured after 120 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human CDK1/cyclinE using RB protein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259155BDBM50259155((Z)-Hymenialdisine | Hymenialdisine)
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK1/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263013BDBM50263013(CHEMBL4079206)
Affinity DataIC50: 76nMAssay Description:Inhibition of CDK1/cyclin E (unknown origin) after 30 mins in presence of [33P]-gamma-ATP by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2020
Entry Details Article
PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270298BDBM50270298(CHEMBL4075720)
Affinity DataIC50: 96nMAssay Description:Inhibition of human CDK1/Cyclin E using RB protein as substrate preincubated for 20 mins followed by [gamma-33P]-ATP addition measure after 120 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2020
Entry Details Article
PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50637886BDBM50637886(Culmerciclib)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of CDK1/Cyclin E1 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367676BDBM50367676(CHEMBL4160662)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662093BDBM50662093(CHEMBL6167007)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50135286BDBM50135286(CHEMBL3745885)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDK1/cyclin E using RP protein as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2017
Entry Details Article
PubMed
TargetCDK1/Cyclin E(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/Cyclin E1 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed