Compile Data Set for Download or QSAR
Report error Found 1489 Enz. Inhib. hit(s) with Target = 'CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7'
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 730258BDBM730258(US20250109156, Compound 1)
Affinity DataIC50: 1nMAssay Description:Experimental Methods:Preparation of kinase buffer: the kinase buffer containing 50 mM HEPES, 1 mM EDTA, 10 mM MgCl2, 0.01% Brij-35, pH 7.4.2.38 g of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 730259BDBM730259(US20250109156, Compound 3)
Affinity DataIC50: 1.10nMAssay Description:Experimental Methods:Preparation of kinase buffer: the kinase buffer containing 50 mM HEPES, 1 mM EDTA, 10 mM MgCl2, 0.01% Brij-35, pH 7.4.2.38 g of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 730299BDBM730299(US20250109156, Compound 5)
Affinity DataIC50: 1.20nMAssay Description:Experimental Methods:Preparation of kinase buffer: the kinase buffer containing 50 mM HEPES, 1 mM EDTA, 10 mM MgCl2, 0.01% Brij-35, pH 7.4.2.38 g of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50539763BDBM50539763(Adagrasib | Mrtx-849 | Mrtx849)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CDK7/Cyclin H/MAT1 (unknown origin) in leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530357BDBM530357(WO2022064009, Compound 148 | WO2022064009, Compoun...)
Affinity DataIC50: 1.38nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 730300BDBM730300(US20250109156, Compound 6)
Affinity DataIC50: 1.40nMAssay Description:Experimental Methods:Preparation of kinase buffer: the kinase buffer containing 50 mM HEPES, 1 mM EDTA, 10 mM MgCl2, 0.01% Brij-35, pH 7.4.2.38 g of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530269BDBM530269(WO2022064009, Compound 13)
Affinity DataIC50: 1.41nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 730298BDBM730298(US20250109156, Compound 4)
Affinity DataIC50: 1.60nMAssay Description:Experimental Methods:Preparation of kinase buffer: the kinase buffer containing 50 mM HEPES, 1 mM EDTA, 10 mM MgCl2, 0.01% Brij-35, pH 7.4.2.38 g of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530396BDBM530396(WO2022064009, Compound 173)
Affinity DataIC50: 1.66nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50644037BDBM50644037(CHEMBL5573062)
Affinity DataKi:  1.70nMAssay Description:Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 60 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530309BDBM530309(WO2022064009, Compound 70)
Affinity DataIC50: 1.78nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530370BDBM530370(WO2022064009, Compound 180a)
Affinity DataIC50: 2.09nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50644019BDBM50644019(CHEMBL5571052)
Affinity DataKi:  2.10nMAssay Description:Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 60 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530249BDBM530249(WO2022064009, Compound 5)
Affinity DataIC50: 2.14nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530318BDBM530318(WO2022064009, Compound 91 | WO2022064009, Compound...)
Affinity DataIC50: 2.14nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530318BDBM530318(WO2022064009, Compound 91 | WO2022064009, Compound...)
Affinity DataIC50: 2.14nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50644054BDBM50644054(CHEMBL5571158)
Affinity DataKi:  2.20nMAssay Description:Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 60 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50648358BDBM50648358(CHEMBL5612622)
Affinity DataKi:  2.20nMAssay Description:Inhibition of recombinant GST-tagged CDK7/CycH/MAT1 (unknown origin) extracted from baculo-virus infected Sf9 insect cells assessed as inhibition con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50583929BDBM50583929(Sy 5609 | Sy-5609 | SY5609 | SY-5609)
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530297BDBM530297(WO2022064009, Compound 58)
Affinity DataIC50: 2.34nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530245BDBM530245(WO2022064009, Compound 51 | WO2022064009, Compound...)
Affinity DataIC50: 2.45nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50583929BDBM50583929(Sy 5609 | Sy-5609 | SY5609 | SY-5609)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human His-tagged CDK7/cyclin H/MNAT1 expressed in baculovirus infected insect cells preincubated for 10 mins followed by substrate and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530266BDBM530266(WO2022064009, Compound 154 | WO2022064009, Compoun...)
Affinity DataIC50: 2.51nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530260BDBM530260(WO2022064009, Compound 37)
Affinity DataIC50: 2.51nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530383BDBM530383(WO2022064009, Compound 160)
Affinity DataIC50: 2.63nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530397BDBM530397(WO2022064009, Compound 174)
Affinity DataIC50: 2.63nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530252BDBM530252(WO2022064009, Compound 8)
Affinity DataIC50: 2.69nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530308BDBM530308(WO2022064009, Compound 69)
Affinity DataIC50: 2.69nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530305BDBM530305(WO2022064009, Compound 66)
Affinity DataIC50: 2.75nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50644819BDBM50644819(CHEMBL5570901)
Affinity DataKi:  2.80nMAssay Description:Inhibition of recombinant human His-tagged CDK7/cyclin H/MNAT1 expressed in baculovirus expression system using histone H1 as substrate preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530401BDBM530401(WO2022064009, Compound 188)
Affinity DataIC50: 2.82nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530280BDBM530280(WO2022064009, Compound 29)
Affinity DataIC50: 2.82nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530310BDBM530310(WO2022064009, Compound 71)
Affinity DataIC50: 2.88nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50644055BDBM50644055(CHEMBL5573958)
Affinity DataKi:  2.90nMAssay Description:Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 60 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50363196BDBM50363196(CHEMBL1944698)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged CDK7/cyclin H/N-terminal GST-tagged MAT1 expressed in baculovirus infected Sf21 in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50644053BDBM50644053(CHEMBL5569632)
Affinity DataKi:  3nMAssay Description:Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 60 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50644037BDBM50644037(CHEMBL5573062)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 60 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 788158BDBM788158(US12473303, Compound H-APPAMP-015)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/8/2026
Entry Details
US Patent

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530335BDBM530335(WO2022064009, Compound 93 | WO2022064009, Compound...)
Affinity DataIC50: 3.02nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530369BDBM530369(WO2022064009, Compound 150)
Affinity DataIC50: 3.16nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530337BDBM530337(WO2022064009, Compound 122b)
Affinity DataIC50: 3.16nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530356BDBM530356(WO2022064009, Compound 134)
Affinity DataIC50: 3.16nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50526797BDBM50526797(Ct-7001 | Ct7001 | ICEC-0942 | ICEC0942 | Samuraci...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 60 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530286BDBM530286(WO2022064009, Compound 156 | WO2022064009, Compoun...)
Affinity DataIC50: 3.24nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530256BDBM530256(WO2022064009, Compound 12)
Affinity DataIC50: 3.24nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530423BDBM530423(WO2022064009, Compound 209)
Affinity DataIC50: 3.31nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530424BDBM530424(WO2022064009, Compound 210)
Affinity DataIC50: 3.31nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50644018BDBM50644018(CHEMBL5573301)
Affinity DataKi:  3.40nMAssay Description:Inhibition of CDK7/cyclin H/MNAT1 (unknown origin) preincubated for 10 mins followed by substrate addition and measured after 60 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530299BDBM530299(WO2022064009, Compound 60)
Affinity DataIC50: 3.55nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

TargetCDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 530354BDBM530354(WO2022064009, Compound 132)
Affinity DataIC50: 3.63nMAssay Description:Inhibition potencies of compounds were studied using an absorbance kinetic assay as described below. Absorbance kinetic assay (5 nM CDK7/Cyclin H/MAT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
WIPO WO2022064009

Displayed 1 to 50 (of 1489 total ) | Next | Last >>
Jump to: