BDBM50614175 CHEMBL5283179

SMILES CCC(=O)Nc1cc(ccc1C)Nc2cc(n3c(n2)c(cn3)C#N)NC4CC4

InChI Key InChIKey=YKDZIFFKQUNVHH-UHFFFAOYSA-N

Data  7 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50614175   

TargetCasein kinase II subunit alpha(Human)
German University in Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614175BDBM50614175(CHEMBL5283179)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant human CK2alpha extracted from Escherichia coli C41 (DE3) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha'(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614175BDBM50614175(CHEMBL5283179)
Affinity DataIC50: 19nMAssay Description:Inhibition of C-terminal Nano-Luc fused human CK2alpha' expressed in HEK293 cells using NanoBRET NanoGlo substrate in presence of tracer K5 by NanoBR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
German University in Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614175BDBM50614175(CHEMBL5283179)
Affinity DataIC50: 36nMAssay Description:Inhibition of C-terminal Nano-Luc fused human CK2alpha expressed in HEK293 cells using NanoBRET NanoGlo substrate in presence of tracer K10 by NanoBR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
German University in Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614175BDBM50614175(CHEMBL5283179)
Affinity DataIC50: 36nMAssay Description:Inhibition of CK2alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRAC-alpha serine/threonine-protein kinase(Human)
German University in Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614175BDBM50614175(CHEMBL5283179)
Affinity DataIC50: 100nMAssay Description:Inhibition of AKT1 phosphorylation in human HCT-116 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
German University in Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614175BDBM50614175(CHEMBL5283179)
Affinity DataIC50: 440nMAssay Description:Inhibition of DRAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEukaryotic translation initiation factor 2 subunit 2(Homo sapiens)
German University in Cairo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50614175BDBM50614175(CHEMBL5283179)
Affinity DataIC50: 500nMAssay Description:Inhibition of eIF2beta phosphorylation in human HCT-116 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed