BDBM50553219 CHEMBL4742985

SMILES c1cc(cc(c1)Nc2nc3c(c(n2)OCC4CCCCC4)nc[nH]3)C(=O)N

InChI Key InChIKey=XAOVCENYRWWHPR-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50553219   

TargetCyclin-dependent kinase 2(Human)
Institute of Respiratory Healthand

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553219BDBM50553219(CHEMBL4742985)
Affinity DataIC50: 480nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553219BDBM50553219(CHEMBL4742985)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant full length His-tagged NEK2 expressed in baculovirus expression system assessed as inhibition of substrate phosphoryl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553219BDBM50553219(CHEMBL4742985)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of NEK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase Nek2(Human)
Newcastle University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553219BDBM50553219(CHEMBL4742985)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of NEK2 (unknown origin) using 5-FAM-KKLNRTLSVA-COOH as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)