BDBM50548151 CHEMBL4747967

SMILES CC(=O)Nc1nc2cc(ccc2s1)O

InChI Key InChIKey=YOMAHEQEXVNJNF-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50548151   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Nirma University

Curated by ChEMBL

LigandBDBM50548151(CHEMBL4747967)Copy SMILESCopy InChI

Affinity DataIC50: 400nMAssay Description:Inhibition of ATR (unknown origin) assessed as reduction in CHK1 phosphorylation by cell based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
6/4/2026
Entry Details PubMedPDB3D Structure (crystal)
Copy reaction URL

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Nirma University

Curated by ChEMBL

LigandBDBM50548151(CHEMBL4747967)Copy SMILESCopy InChI

Affinity DataIC50: 800nMAssay Description:Inhibition of DYRK1A (unknown origin) by [33P]-ATP filter binding kinase assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidPDBSimilars

In Depth
Date in BDB:
3/22/2022
Entry Details Article
Copy BDB DOIPubMedPDB3D Structure (crystal)
Copy reaction URL