BDBM50434122 CHEMBL1232568

SMILES c1cc2c(cc1Cl)NC(=O)C2

InChI Key InChIKey=CENVPIZOTHULGJ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 3 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50434122   

TargetAryl hydrocarbon receptor(Human)
Palacky University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434122BDBM50434122(CHEMBL1232568)
Affinity DataEC50:  140nMAssay Description:Inhibition of mouse SGLT2-mediated [14C]alpha-methylglucopyranoside uptake by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAryl hydrocarbon receptor(Mouse)
Palacky University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434122BDBM50434122(CHEMBL1232568)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of HCV NS5A Y93H mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAryl hydrocarbon receptor(Mouse)
Palacky University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434122BDBM50434122(CHEMBL1232568)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of HCV NS5A L31V mutant in HCV genotype 1a assessed as reduction in viral replication by cell based replicon assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetAryl hydrocarbon receptor(Human)
Palacky University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434122BDBM50434122(CHEMBL1232568)
Affinity DataEC50:  2.51E+4nMAssay Description:Inhibition of Flt3 activity in human MV 3:11 cells by phosphotyrosine cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetChymase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434122BDBM50434122(CHEMBL1232568)
Affinity DataIC50: 4.70E+5nMAssay Description:Inhibition of recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCathepsin G(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50434122BDBM50434122(CHEMBL1232568)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human cathepsin G using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed