BDBM50656340 Minalrestat::WAY-ARI-509

SMILES O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1ccc(F)cc12

InChI Key InChIKey=BMHZAHGTGIZZCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50656340   

TargetAldo-keto reductase family 1 member B1(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656340BDBM50656340(Minalrestat | WAY-ARI-509)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal 6his-tagged wild type human recombinant AKR1B1 extracted from Escherichia coli BL21 (DE3) by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetAldo-keto reductase family 1 member B10(Human)
University of Messina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50656340BDBM50656340(Minalrestat | WAY-ARI-509)
Affinity DataIC50: 740nMAssay Description:Inhibition of AKR1B10 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed