BDBM50007906 Meldonium

SMILES C[N+](C)(C)NCCC([O-])=O

InChI Key InChIKey=PVBQYTCFVWZSJK-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50007906   

TargetGamma-butyrobetaine dioxygenase(Human)
Latvian Biomedical Research and Study Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007906BDBM50007906(Meldonium)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of BBOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetGamma-butyrobetaine dioxygenase(Human)
Latvian Biomedical Research and Study Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007906BDBM50007906(Meldonium)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full-length recombinant human BBOX using GBB/2-OG as substrate preincubated for 15 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAspartyl/asparaginyl beta-hydroxylase(Human)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007906BDBM50007906(Meldonium)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human AspH (315 to 758 residues) extracted from Escherichia coli BL21 (DE3) cells using hFX-CP/2-OG ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007906BDBM50007906(Meldonium)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant truncated human PHD2 (181 to 426 residues) extracted from Escherichia coli BL21 DE3 cells using HIF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007906BDBM50007906(Meldonium)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of His6-tagged recombinant human KDM4A (1 to 359 residues) using H3K9me3/2-OG as substrate by SPE-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBifunctional peptidase and arginyl-hydroxylase JMJD5(Homo sapiens)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007906BDBM50007906(Meldonium)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-thioredoxin-tagged full-length recombinant human JMJD5 (1 to 416 residues) extracted from Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGamma-butyrobetaine dioxygenase(Human)
Latvian Biomedical Research and Study Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007906BDBM50007906(Meldonium)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of human recombinant BBOX expressed in Saccharomyces cerevisiae AH22 assessed as formation of carnitine from gamma-butyrobetaine preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetGamma-butyrobetaine dioxygenase(Human)
Latvian Biomedical Research and Study Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50007906BDBM50007906(Meldonium)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of recombinant human BBOX extracted from Escherichia coli WK6 incubated for 120 mins by UPLC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed