BDBM50521239 CHEMBL4443026

SMILES CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCN(CC(=O)NCCOCCOCCOCCNc4cccc5c4C(=O)N(C4CCC(=O)NC4=O)C5=O)CC3)s2)o1

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50521239   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521239BDBM50521239(CPD 2 | THAL-SNS-032 | CHEMBL4587232)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521239BDBM50521239(CPD 2 | THAL-SNS-032 | CHEMBL4587232)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetMitogen-activated protein kinase 15(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521239BDBM50521239(CPD 2 | THAL-SNS-032 | CHEMBL4587232)
Affinity DataIC50: 79nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetPeripheral plasma membrane protein CASK(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521239BDBM50521239(CPD 2 | THAL-SNS-032 | CHEMBL4587232)
Affinity DataIC50: 440nMAssay Description:Activity at human PPARalpha receptor by cell based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521239BDBM50521239(CPD 2 | THAL-SNS-032 | CHEMBL4587232)
Affinity DataIC50: 2.70E+3nMAssay Description:Activity at human PPARgamma receptor by cell based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521239BDBM50521239(CPD 2 | THAL-SNS-032 | CHEMBL4587232)
Affinity DataEC50:  3.10E+3nMAssay Description:Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetNuclear receptor subfamily 1 group I member 3(Human)
St. Jude Children's Research Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50521239BDBM50521239(CPD 2 | THAL-SNS-032 | CHEMBL4587232)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed