BDBM50450015 Bms-955176::GSK-3532795

SMILES [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC=C(c4ccc(cc4)C(O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)NCCN1CCS(=O)(=O)CC1)C(C)=C

InChI Key InChIKey=XDMUFNNPLXHNKA-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50450015   

TargetGag polyprotein(Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450015BDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataKd:  3.20nMAssay Description:Binding affinity to wild type HIV1 gag polyprotein containing viral like particleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450015BDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataKd:  4.30nMAssay Description:Binding affinity to HIV1 gag polyprotein V362I mutant containing viral like particleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450015BDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataKd:  6.5nMAssay Description:Binding affinity to HIV1 gag polyprotein V370A mutant containing viral like particleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450015BDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataKd:  34nMAssay Description:Binding affinity to HIV1 gag polyprotein delta V370 mutant containing viral like particleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450015BDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataKd:  98nMAssay Description:Binding affinity to HIV1 gag polyprotein A364V mutant containing viral like particleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
University of Rwanda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450015BDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human adenosine A1 receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Rwanda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450015BDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of KDR (unknown origin) in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetStructural capsid protein(Human immunodeficiency virus type 1)
University of Rwanda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450015BDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of KDR (unknown origin) in cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Rwanda

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50450015BDBM50450015(Bms-955176 | GSK-3532795)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at human adenosine A2A receptor assessed as cAMP level by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed