BDBM96683 2-[2-(4-fluorophenyl)ethylcarbamoyl]cyclohexane-1-carboxylic acid::2-[2-(4-fluorophenyl)ethylcarbamoyl]cyclohexanecarboxylic acid::2-[[2-(4-fluorophenyl)ethylamino]-oxomethyl]-1-cyclohexanecarboxylic acid::MLS000714163::SMR000274143::cid_3112062

SMILES Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1CCc1cc(Nc2cnccn2)[nH]n1

InChI Key InChIKey=WSXUCWDHQOSETM-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 96683   

TargetVascular endothelial growth factor receptor 2(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96683BDBM96683(N-(4-methyl-3-(2-(5-(pyrazin-2-ylamino)-1H-pyrazol...)
Affinity DataIC50: 7nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Fyn(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96683BDBM96683(N-(4-methyl-3-(2-(5-(pyrazin-2-ylamino)-1H-pyrazol...)
Affinity DataIC50: 9nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Yes(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96683BDBM96683(N-(4-methyl-3-(2-(5-(pyrazin-2-ylamino)-1H-pyrazol...)
Affinity DataIC50: 17nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent

TargetTyrosine-protein kinase Lyn(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96683BDBM96683(N-(4-methyl-3-(2-(5-(pyrazin-2-ylamino)-1H-pyrazol...)
Affinity DataIC50: 59nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96683BDBM96683(N-(4-methyl-3-(2-(5-(pyrazin-2-ylamino)-1H-pyrazol...)
Affinity DataIC50: 370nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96683BDBM96683(N-(4-methyl-3-(2-(5-(pyrazin-2-ylamino)-1H-pyrazol...)
Affinity DataIC50: 1.76E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent

TargetFibroblast growth factor receptor 2(Human)
Rottapharm Biotech

US Patent
LigandChemical structure of BindingDB Monomer ID 96683BDBM96683(N-(4-methyl-3-(2-(5-(pyrazin-2-ylamino)-1H-pyrazol...)
Affinity DataIC50: 3.00E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2026
Entry Details
US Patent