BDBM95595 2-(3-isopropoxyphenyl)-N-morpholino-cinchoninamide::MLS001125185::N-(4-morpholinyl)-2-(3-propan-2-yloxyphenyl)-4-quinolinecarboxamide::N-morpholin-4-yl-2-(3-propan-2-yloxyphenyl)quinoline-4-carboxamide::SMR000668808::cid_2220729

SMILES COc1ccc(F)c(-n2ncc3c2COC[C@H]3NC(=O)c2ncn3c2CCCC3)c1Cl

InChI Key InChIKey=SXRCDCDPJRHZEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 95595   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetCytochrome P450 2B6(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetCytochrome P450 2A6(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetCytochrome P450 2C8(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

Targetcyp2d6(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetCytochrome P450 2C19(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetCytochrome P450 2E1(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Genase Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 95595BDBM95595(US20250388602, Example 9)
Affinity DataIC50: 3.00E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent