BDBM88574 US20250388593, Example 131::tert-Butyl 6-(6,8-dioxo-2,7-diazaspiro [4.6]undec-9-en-2-yl) pyridine-3-carboxylate

SMILES CC(C)(C)OC(=O)c1ccc(N2CCC3(CC=CC(=O)NC3=O)C2)nc1

InChI Key InChIKey=DJAODXYPGMGEAU-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 88574   

TargetProtein cereblon [318-426](Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 88574BDBM88574(tert-Butyl 6-(6,8-dioxo-2,7-diazaspiro [4.6]undec-...)
Affinity DataKd: >1.00E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent