BDBM85592 AANAT Inhibitor, 12d

SMILES Oc1ccc2scc(CCNC(=O)CBr)c2c1

InChI Key InChIKey=RAFULIQYRQZSBR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 85592   

TargetSerotonin N-acetyltransferase(Human)
UniversitÉ

LigandChemical structure of BindingDB Monomer ID 85592BDBM85592(AANAT Inhibitor, 12d)
Affinity DataIC50: 180nMpH: 6.8 T: 2°CAssay Description:The compounds were evaluated in a human serotonin N-acetyltransferase assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2012
Entry Details Article
PubMed
TargetSerotonin N-acetyltransferase(Human)
UniversitÉ

LigandChemical structure of BindingDB Monomer ID 85592BDBM85592(AANAT Inhibitor, 12d)
Affinity DataIC50: 180nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetSerotonin N-acetyltransferase(Sheep)
University of Nebraska at Kearney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 85592BDBM85592(AANAT Inhibitor, 12d)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity (unknown origin) by cell based ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed