BDBM83345 (1-ethylpyrazol-4-yl)methyl-[[3-(3-fluoro-4-methoxy-phenyl)-1-(o-tolyl)pyrazol-4-yl]methyl]amine::1-(1-ethyl-1H-pyrazol-4-yl)-N-{[3-(3-fluoro-4-methoxyphenyl)-1-(2-methylphenyl)-1H-pyrazol-4-yl]methyl}methanamine::1-(1-ethyl-4-pyrazolyl)-N-[[3-(3-fluoro-4-methoxyphenyl)-1-(2-methylphenyl)-4-pyrazolyl]methyl]methanamine::1-(1-ethylpyrazol-4-yl)-N-[[3-(3-fluoranyl-4-methoxy-phenyl)-1-(2-methylphenyl)pyrazol-4-yl]methyl]methanamine::1-(1-ethylpyrazol-4-yl)-N-[[3-(3-fluoro-4-methoxyphenyl)-1-(2-methylphenyl)pyrazol-4-yl]methyl]methanamine::MLS000731922::SMR000315664::cid_16189942

SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2cc3c(nc21)CCN3

InChI Key InChIKey=QMUMNUDQNJPSSV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 83345   

TargetTyrosine-protein kinase Lck(Human)
Engine Biosciences

US Patent
LigandChemical structure of BindingDB Monomer ID 83345BDBM83345(US20250388583, Compound 604 | US20260001879, Compo...)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 83345BDBM83345(US20250388583, Compound 604 | US20260001879, Compo...)
Affinity DataIC50: 50nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Wigen Biommedicine Technology (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 83345BDBM83345(US20250388583, Compound 604 | US20260001879, Compo...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Wigen Biommedicine Technology (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 83345BDBM83345(US20250388583, Compound 604 | US20260001879, Compo...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetMyelin transcription factor 1(Human)
Wigen Biommedicine Technology (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 83345BDBM83345(US20250388583, Compound 604 | US20260001879, Compo...)
Affinity DataIC50: 200nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent