BDBM79951 MLS002166024::N-(2-methylphenyl)-1-[2-(trifluoromethyl)phenyl]sulfonyl-2-pyrrolidinecarboxamide::N-(2-methylphenyl)-1-[2-(trifluoromethyl)phenyl]sulfonyl-pyrrolidine-2-carboxamide::N-(2-methylphenyl)-1-[2-(trifluoromethyl)phenyl]sulfonylpyrrolidine-2-carboxamide::N-(o-tolyl)-1-[2-(trifluoromethyl)phenyl]sulfonyl-pyrrolidine-2-carboxamide::SMR001248382::cid_4879906

SMILES Cn1cc(-c2cc(S(=O)(=O)CCCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O

InChI Key InChIKey=OSNAZRTWDFNNGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 79951   

TargetProgesterone receptor ligand binding domain (LBD)(Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79951BDBM79951(US20250388575, Compound I-92)
Affinity DataIC50: 55nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBromodomain-containing protein 4 [58-164](Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79951BDBM79951(US20250388575, Compound I-92)
Affinity DataKd:  5.50E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79951BDBM79951(US20250388575, Compound I-92)
Affinity DataKd:  5.50E+3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent