BDBM79927 MLS000937074::N-(3-methylsulfanylphenyl)-1-thiophen-2-ylsulfonyl-piperidine-3-carboxamide::N-(3-methylsulfanylphenyl)-1-thiophen-2-ylsulfonylpiperidine-3-carboxamide::N-[3-(methylthio)phenyl]-1-(2-thienylsulfonyl)nipecotamide::N-[3-(methylthio)phenyl]-1-thiophen-2-ylsulfonyl-3-piperidinecarboxamide::SMR000621864::cid_22429402

SMILES CCS(=O)(=O)Nc1ccc(Oc2cccc(OCCOC3CCN(c4ccc(C(=O)N[C@H]5CC[C@H](Oc6ccc(C#N)c(Cl)c6)CC5)nn4)CC3)c2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1

InChI Key InChIKey=LZCBNRHAAUTAMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 79927   

TargetAndrogen receptor(Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79927BDBM79927(US20250388575, Compound I-1)
Affinity DataKd: <10nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetProgesterone receptor ligand binding domain (LBD)(Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79927BDBM79927(US20250388575, Compound I-1)
Affinity DataKi:  550nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetProgesterone receptor ligand binding domain (LBD)(Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79927BDBM79927(US20250388575, Compound I-1)
Affinity DataIC50: 550nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent