BDBM79455 8-fluoranyl-5-[(4-fluorophenyl)methyl]-2-[(3-methoxyphenyl)methyl]pyrazolo[4,3-c]quinolin-3-one::8-fluoro-5-(4-fluorobenzyl)-2-m-anisyl-pyrazolo[4,3-c]quinolin-3-one::8-fluoro-5-[(4-fluorophenyl)methyl]-2-[(3-methoxyphenyl)methyl]-3-pyrazolo[4,3-c]quinolinone::8-fluoro-5-[(4-fluorophenyl)methyl]-2-[(3-methoxyphenyl)methyl]pyrazolo[4,3-c]quinolin-3-one::SR-01000805417::SR-01000805417-1::cid_20918677

SMILES FC(F)(F)c1ccc(-c2ccc3c(c2)C2CC3CCN2C2CCCC2)cc1

InChI Key InChIKey=QETRQNGMXMPCNW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79455   

TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79455BDBM79455(US20250387403, Example Table1.32)
Affinity DataKi:  61nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetSigma intracellular receptor 2(Human)
Adam Mickiewicz University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79455BDBM79455(US20250387403, Example Table1.32)
Affinity DataKi:  82.3nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent