BDBM791976 2-(1-(benzo[d][1,3]dioxole-5-yl)-2,5-dimethyl-1H-pyrrol-3-yl)-6-bromo-N-(4-(2-methoxyethoxy)phenyl)-3H-imidazo[4,5-b]pyridine-7-amine::US12545673, Example 45

SMILES COCCOc1ccc(Nc2c(Br)cnc3[nH]c(-c4cc(C)n(-c5ccc6c(c5)OCO6)c4C)nc23)cc1

InChI Key InChIKey=HJIHGTWRSJGVGM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 791976   

TargetMitogen-activated protein kinase kinase kinase 11(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791976BDBM791976(2-(1-(benzo[d][1,3]dioxole-5-yl)-2,5-dimethyl-1H-p...)
Affinity DataIC50: 32nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 9(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791976BDBM791976(2-(1-(benzo[d][1,3]dioxole-5-yl)-2,5-dimethyl-1H-p...)
Affinity DataIC50: 85nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 10(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791976BDBM791976(2-(1-(benzo[d][1,3]dioxole-5-yl)-2,5-dimethyl-1H-p...)
Affinity DataIC50: 524nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details
US Patent