BDBM791975 3-(3-(7-(benzo[d][1,3]dioxole-5-yl-amino)-6-bromo-3H-imidazo[4,5-b]pyridine-2-yl)-2,5-dimethyl-1H-pyrrol-1-yl)benzenesulfonamide::US12545673, Example 44

SMILES Cc1cc(-c2nc3c(Nc4ccc5c(c4)OCO5)c(Br)cnc3[nH]2)c(C)n1-c1cccc(S(N)(=O)=O)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 791975   

TargetMitogen-activated protein kinase kinase kinase 11(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791975BDBM791975(3-(3-(7-(benzo[d][1,3]dioxole-5-yl-amino)-6-bromo-...)
Affinity DataIC50: 27nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

TargetMitogen-activated protein kinase kinase kinase 9(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791975BDBM791975(3-(3-(7-(benzo[d][1,3]dioxole-5-yl-amino)-6-bromo-...)
Affinity DataIC50: 109nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

TargetMitogen-activated protein kinase kinase kinase 10(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791975BDBM791975(3-(3-(7-(benzo[d][1,3]dioxole-5-yl-amino)-6-bromo-...)
Affinity DataIC50: 211nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent