BDBM791959 3-((6-bromo-2-(2,5-dimethyl-1-(4-(morpholine-4-carbonyl)phenyl)-1H-pyrrol-3-yl)-3H-imidazo[4,5-b]pyridine-7-yl)amino)benzenesulfonamide::US12545673, Example 27

SMILES Cc1cc(-c2nc3c(Nc4cccc(S(N)(=O)=O)c4)c(Br)cnc3[nH]2)c(C)n1-c1ccc(C(=O)N2CCOCC2)cc1

InChI Key InChIKey=CQYKDYHDMBORSI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 791959   

TargetMitogen-activated protein kinase kinase kinase 11(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791959BDBM791959(3-((6-bromo-2-(2,5-dimethyl-1-(4-(morpholine-4-car...)
Affinity DataIC50: 20nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 9(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791959BDBM791959(3-((6-bromo-2-(2,5-dimethyl-1-(4-(morpholine-4-car...)
Affinity DataIC50: 176nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 10(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791959BDBM791959(3-((6-bromo-2-(2,5-dimethyl-1-(4-(morpholine-4-car...)
Affinity DataIC50: 178nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details
US Patent