BDBM791957 (S)-6-bromo-2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)-N-(1-(ethylsulfonyl) pyrrolidine-3-yl)-3H-imidazo[4,5-b]pyridine-7-amine::US12545673, Example 25

SMILES CCS(=O)(=O)N1CCC(Nc2c(Br)cnc3[nH]c(-c4cc(C)n(-c5ccccc5)c4C)nc23)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 791957   

TargetMitogen-activated protein kinase kinase kinase 11(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791957BDBM791957((S)-6-bromo-2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-y...)
Affinity DataIC50: 26nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

TargetMitogen-activated protein kinase kinase kinase 9(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791957BDBM791957((S)-6-bromo-2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-y...)
Affinity DataIC50: 71nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

TargetMitogen-activated protein kinase kinase kinase 10(Human)
TSD Life Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 791957BDBM791957((S)-6-bromo-2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-y...)
Affinity DataIC50: 250nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent